A series of investigations were conducted in order to evaluate the effect of MOS supplementation in finfish aquaculture. Fish with great potential in aquaculture industry were tested with regards to effect of dietary MOS supplementation on intestinal histology and microbiology as well as overall animal health and production. Two levels of MOS supplementation were applied 0.2% and 0.4%. Experimental fish were Atlantic salmon (Salmon salar), rainbow trout (Oncorhynchys mykiss), sole (Solea senegalensis) and gilthead sea bream (Sparus aurata). The results from the sea bream studies revealed that MOS supplementation may have a beneficial effect on growth performance of fish greater than 100 g. Additionally, there is a systemic improvement of the intestinal histology for all species investigated, especially when using 0.4% of MOS supplementation level. Both light and electron microscopy revealed increased intestinal surface and improved intestinal integrity of MOS fed fish. MOS alters the intestinal microbiota, in the case of gilthead sea bream modulation was evident even when fish were fed 0.2% dietary MOS for as little as 2 weeks. Blood immune parameters were also affected by the MOS inclusion and total leukocytes counts were increased and leukocytes relative abundance was also changed. MOS induced intestinal microbial modulation was more evident in fish are reared in outdoor conditions. Feed utilization and digestibility were improved with the addition of 0.4% MOS supplementation in the Atlantic salmon. The sole experiment revealed that MOS could reduce fish mortalities induced by pasteurelliosis. These investigations, suggest a potential role for application of MOS in aquaculture. Future research should be conducted in order to evaluate other parameters that MOS may influence and ascertain optimum dosage for each fish species and developmental stage.

DIPLOMA THESIS: Safety of selected dietary supplements with regard to the content of food additives SOCIAL AND CLINICAL PHARMACY DEPARTMENT, FACULTY OF PHARMACY IN HRADEC KRÁLOVÉ, CHARLES UNIVERSITY IN PRAGUE AUTHOR: Jana Tížková SUPERVISOR: PharmDr. Jitka Pokladníková, Ph.D. INTRODUCTION: Usage of dietary supplements is increasing each year. But with this trend there are also concerns about their possible damaging influence, mostly due to present food additives. I have decided to map safety of dietary supplements from food additives point of view, because of spare information about their potential harmfulness. OBJECTIVE: Goal of this work is to evaluate safety of bestselling immune system support according to food additives that they contain and analysis of most commonly occurring harmful additives influence on human health. METHODOLOGY: List of bestselling dietary supplements was gathered from one of pharmaceutical chain brand. Data came from diverse list of dietary supplements, from which I have chosen those with supporting effect on immune system. They contain mostly substances gathered from Echinacea plants, specifically Echinacea angustifolia, pallida, purpurea, mushroom Pleurotus ostreatus, also those containing Probiotics, Royal jelly and mixture of oligosaccharides, nucleotides and...

Effectiveness and safety of selected dietary supplements Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University in Prague Student: Kateřina Smolíková Tutor: PharmDr. Jitka Pokladníková, Ph.D. Introduction: The market for dietary supplements in recent years has seen a noticeable upswing and supplements become for some people part of their daily lives, which could mean potential risks. Objectives: To assess the effectiveness and risks of selected dietary supplements containing Vaccinium macrocarpon, Serenoa repens, Cimicifuga racemosa, Glycine max and Silybum marianum. At the same time, the aim of this work was to evaluate the safety of selected supplements from the point of view of content of additives, check undesirable effects of harmful additives and compare them with the identified undesirable effects of medicinal plants. Methods: Efficacy and safety were assessed on the basis of scientific studies. It has been rated 5 best-selling groups of food supplements in 2011. The list of 100 best-selling nutritional supplements in the Czech Republic were given to us by one pharmacy chain. From the most selling supplements was made a list of the most frequently occurring substances content which was sent to the Ministry of Health with a request to add...

Safety of the selected food supplements in terms of the presence of additives Additives are commonly present not only in food, but also in food supplements. Safety of these substances remains a question. The aim of the theses is to evaluate the safety of the best selling supplements in the Czech Republic in the year 2011 from the viewpoint of additives and constituents. Given the scale of researched products, I focused on products strengthening the cardiovascular system containing omega 3 fatty acids , garlic, coenzyme Q 10 and lecithin. As a source of information about the content and the presence of additives, the data from the Ministry of Health and the Information System decision of the Chief Hygienist (IS RoHy) were used. The safety evaluation of additives was carried out on the basis of the available methodology for consumers. Information about adverse effects of additives and content substances were searched using information databases Martindale , Reprotox, AltMedDex, Drugdex, National Center for Complementary and Alternative Medicine (NCCAM), IPCS INCHEM, PubMed independent commission database JECFA Joint FAO / WHO Expert committee on Food additives. Descriptive statistics was used. Of the large number of products (97), 5 products were classified as safe and 92 as products harmful to...

SAFETY OF THE SELECTED FOOD SUPPLEMENTS FROM VIEWPOINT OF THE PRESENCE ADDITIVES. Student: Renáta Jajtnerová Tutor: PharmDr. Jitka Pokladníková, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University in Prague Introduction: Nowadays the additives are absolutely common part of our life and we encounter with them almost daily. We can find them not only in food but also in drugs or various food supplements. Their safety is often discuss and the opinions of individual experts are often different. Objective: The aim of this work is to evaluate the safety of food supplements in terms of the presence of food additives and their possible interactions with substances. The evaluation concern food supplements which occurred on the Czech market in 2011. Because the number of food supplements on our market is very high, I focused only on the supplements used for the support joints and for the treatment of osteoarthritis. Methodology: One of the pharmaceutical chains provided for us the list of best- selling products and the complete list of products we received from the Ministry of health. Than the composition of these supplements was sought on the Information system decision of the chief hygienist (Is RoHy) alternatively in the pharmacy or directly from the...

Master of Science / Food Science - Animal Sciences & Industry / Fadi M. Aramouni / Food product development involves more than just creating the perfect recipe. Representatives from marketing, procurement, research and development, safety, and quality all work together to complete product development projects. This manuscript is aimed to serve food science students and professionals learning the basics of the product development process, food component functionality, basic units of food processing, regulatory considerations, food safety concepts, consumer testing, confidentiality/ intellectual property issues, and essential pieces of marketing. Many other texts concentrate on food product development, but this text looks to create a more comprehensive guide. The breadth of knowledge needed for food product development are vast. Food science students and professionals can use this text to provide basic (not exhaustive) knowledge necessary to be a valuable part of a new product development team.

Regardless of the type of diet used, the search for increased digestion of nutrients has been the target of most research worldwide. The objective of this thesis was to evaluate the effects of the inclusion of essential oils, enzymes, ionophores and combinations of additives in animal performance, ruminal health and apparent digestibility in Nellore cattle fed with high concentrate diets. The study was composed of two performance experiments and two of metabolism In Chapter 1 of this thesis 2 experiments were conducted to evaluate the performance responses of finishing feedlot cattle receiving diets containing essential oils and exogenous enzymes. The treatments in each experiment consisted of (dry matter basis): MON - sodium monensin (26 mg/kg); BEO - a blend of essential oils (90 mg/kg); BEO+MON - a blend of essential oils plus monensin (90 mg/kg + 26 mg/kg, respectively); BEO+AM - a blend of essential oils plus exogenous α-amylase (90 mg/kg + 560 mg/kg, respectively); and BEO+AM+PRO - a blend of essential oils plus exogenous α-amylase and exogenous protease (90 mg/kg + 560 mg/kg + 840, mg/kg respectively). Exp. 1 consisted of a 93-d finishing period using 300 Nellore bulls in a randomized complete block design. Compared with MON, the combination of BEO+AM resulted in greater dry matter intake, greater average daily gain, 12 kg heavier hot carcass weight, although feed efficiency was not significantly different between BEO+AM and MON. BEO+MON and BEO did not improve performance when compared to MON. In Exp. 2, five ruminally cannulated Nellore steers were used to evaluate intake, apparent total tract digestibility of nutrients, and ruminal parameters in a 5 × 5 Latin Square design. Intakes of all nutrients measured, except for EE were greater in animals fed BEO+AM when compared with MON, with no differences on total tract nutrient digestibilities between these two treatments. Feeding BEO increased the total tract digestibility of CP compared to MON. In summary, diets containing the BEO used herein enhanced dry matter intake of growing-finishing feedlot cattle compared with a basal diet containing MON without impair feed efficiency. A synergism between BEO and AM was detected, resulting in increased carcass production. This study evaluated the growth performance and digestion responses of finishing feedlot beef cattle fed high-concentrate diets containing 82.5% flint corn (DM basis) ground to medium (1.66 mm; MG) or coarse particle sizes (2.12 mm; CG), added with monensin (26 mg/kg; DM basis; MON) or a blend of essential oils + exogenous α-amylase (90 mg/kg + 560 mg/kg commercial product, respectively, DM basis; BEO+AM). In Exp. 1, 256 Nellore bulls were blocked by initial body weight (360 ± 12 kg), assigned to 48 pens and pens within blocks were randomly assigned, in a 2 × 2 factorial arrangement, to treatments during 99 d. Feed additive effect was detected for DMI, which was greater for bulls fed BEO+AM vs. MON. The HCW was 11 kg heavier for bulls fed BEO+AM vs. MON in diets containing CG, but not MG particle size. In Exp. 2, four ruminally cannulated Nellore steers were offered the same treatments of Exp. 1, in a 4 × 4 Latin Square design, to evaluate intake, apparent total tract digestibility of diets and ruminal fermentation parameters. Effect of corn particle size was detected for intake of DM, CP, NDF, NFC, starch and TDN which were greater for steers fed CG than steers fed MG corn. Feed additive affected (P = 0.02) ruminal NH3-N concentration, which was less for steers fed BEO+AM compared to MON. In summary, reducing flint corn particle size from 2.12 to 1.66 mm in finishing diets failed to improve cattle growth performance, digestibility of most nutrients and ruminal fermentation characteristics. A blend of essential oils associated with exogenous α-amylase resulted in the heavier carcass weights compared to monensin supplementation when included in diets containing coarse ground corn. / Independente do tipo de dieta utilizada, a busca por aumento da digestão dos nutrientes tem sido alvo da maior parte das pesquisas realizadas no mundo. O objetivo dessa tese foi avaliar os efeitos da inclusão de óleos essenciais, enzimas, ionóforos e combinações de aditivos na performance animal, saúde ruminal e digestibilidade aparente em bovinos de corte da raça Nelore confinados alimentados com dietas de terminação com alto concentrado. O estudo foi composto por dois experimentos de desempenho e dois de metabolismo. No Capítulo 1 dessa tese 2 experimentos foram conduzidos para avaliar o desempenho de bovinos terminados em confinamento recebendo dietas que continham óleos essências e enzimas exógenas. Os tratamentos em cada experimento consistiram em: MON (monensina sódica, 26 mg/Kg); BEO (blend de óleos essenciais - 90 mg/kg); BEO+MON; BEO+AM (blend de óleos essenciais mais α-amilase - 90 mg/kg + 560 mg/kg, respectivamente) e BEO+AM+PRO (óleos essenciais mais α-amilase mais protease (90 mg/kg + 560 mg/kg + 840 mg/kg, respectivamente). No Exp. 1 foram utilizados 300 animais Nelore distribuídos aleatoriamente em 60 baias. Comparado com MON, a combinação BEO+AM resultou em maior CMS, maior GPD e proporcionou 12 kg a mais de carcaça, sem alterar a eficiência alimentar. BEO+MON e BEO não proporcionaram melhora no desempenho, quando comparada com MON. No Exp. 2, 5 animais canulados no rúmen foram usados para avaliar, CMS, digestibilidade aparente dos nutrientes e parâmetros ruminais em um quadrado latino 5 x 5. BEO aumentou a digestibilidade no trato total da PB comparada com MON. Os consumos de todos nutrientes, com exceção de EE foram maiores para animais alimentados com BEO+AM, quando comparados com MON, sem diferenças na digestibilidade no trato total. Em resumo, BEO aumenta o CMS de animais confinados em relação a MON, sem alterar a eficiência alimentar. Um sinergismo entre BEO e AM foi observado, resultando em aumento da produção de carcaça. No Capítulo 2, avaliou-se o desempenho e respostas metabólicas de animais confinados recebendo dietas com alto teor de milho (82.5% da MS), processado em moído (1,66 mm; MG) e moído grosso (2,12 mm; CG), combinado com monensina (monensina sódica, 26 mg/Kg; MON) ou com blend de óleos essenciais mais α-amilase (90 mg/kg + 560 mg/kg, respectivamente; BEO+MON). No Exp. 1, 256 animais Nelore foram blocados em 48 baias, as quais foram distribuídas aleatoriamente a um arranjo fatorial 2 x 2 nos tratamentos por 99 dias. Animais alimentados com BEO+MON apresentaram maior CMS do que animais alimentados com MON. Foi observada interação entre processamento e aditivo para PCQ, na qual animal alimentados com BEO+MON e CG obtiveram 11 kg a mais. No Exp. 2, quatro animais canulados no rúmen foram assimilados as mesmos tratamentos do Exp. 1, em um quadrado latino 4 x 4. Efeito de processamento foi detectado no consumo de MS, PB, FDN, CNF, amido e NDT, os quais foram maiores para animais alimentados com milho CG do que MG. Efeito de aditivo foi observado na concentração de NH3-N ruminal, a qual foi menor para animais alimentados com BEO+AM comparado a animais que receberam MON. Em suma, reduzir o tamanho de partícula de 2,12 mm para 1,66 mm não melhorou o desempenho e os parâmetros de fermentação ruminal. A suplementação com BEO+AM resulta em maior produção de carcaça comparada com monensina, quando incluída em dietas com milho moído grosseiramente.

Orientador: Dirlei Antonio Berto / Resumo: O objetivo deste trabalho foi avaliar combinações dos prebióticos mananoligossacarídeo, β-glucano, frutoligossacarídeo e galactoligossacarídeo, em substituição ao antimicrobiano halquinol, em dietas de leitões recém-desmamados, sobre o desempenho, incidência de diarreia, saúde intestinal, parâmetros hematológicos e imunológicos. Foram realizados três experimentos, utilizando o total de 200 leitões recémdesmamados com idade média de 21 dias, distribuídos em delineamento em blocos inteiramente casualizados, com cinco tratamentos e oito repetições. Os tratamentos foram constituídos: CON = dieta basal (DB) + 120 ppm de halquinol; Mβ = DB + MOS e β-glucano (3,0 kg/t); F9G1 = DB + MOS e β-glucano (2,0 kg/t) + FOS e GOS (1,0 kg/t) (relação FOS:GOS 9:1); F7G3 = DB + MOS e β-glucano (2,0 kg/t) + FOS e GOS (1,0 kg/t) (relação FOS:GOS 7:3); F5G5 = DB + MOS e β-glucano (2,0 kg/t) + FOS e GOS (1,0 kg/t) (relação FOS:GOS 5:5). No período de 0-15d, os animais dos tratamentos CON e F9G1, apresentaram melhor (P<0,05) conversão alimentar (CA) que os animais do tratamento Mβ. No período de 0-28d, os animas do tratamento F9G1 apresentaram tendência de melhor (P<0,10) CA. No período de 0-41d, os animais do tratamento CON apresentaram melhor (P<0,05) CA em comparação aos animais do F7G3, não diferindo dos demais tratamentos. Ao 14º dia experimental, 40 leitões foram abatidos para coleta de amostras, e outros 40 leitões receberam injeção via intramuscular de lipopolissacarídeo (LPS) de Escherichia ... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: The aim of this work was to evaluate prebiotic combinations of mannanigosaccharide, β-glucan, fructoligosaccharide and galactoligosaccharide, in substituin to antimicrobial halquinol, in diets of weanling pigs, on the performance, diarrhea incidence, intestinal health, hematological and immunological parameters. It were carried out three experiments, using a total of 200 weanling pigs, 21 d-old in average, distributed in a completely randomized block design with five treatments and eight replicates. The treatments were: CON = basal diet (BD) + 120 ppm of halquinol; Mβ = BD + MOS and β-glucan (3.0 kg/t); F9G1 = BD + MOS and β-glucan (2.0 kg/t) + FOS and GOS (1.0 kg/t) (FOS: GOS ratio 9:1); F7G3 = BD + MOS and β-glucan (2.0 kg/t) + FOS and GOS (1.0 kg/t) (FOS: GOS ratio 7:3); F5G5 = BD + MOS and β-glucan (2.0 kg/t) + FOS and GOS (1.0 kg/t) (FOS:GOS ratio 5:5). In the period of 0-15d, the animals of CON and F9G1 treatments presented better (P<0.05) feed conversion ratio (FCR) compared to the animals of Mβ treatment. In the period of 0-28d, the animals from F9G1 treatment tended to improve (P<0.10) FCR. In the period of 0-41d, animals fed CON treatment showed better (P<0.05) FCR compared to the animals fed F7G3, not differing from the other treatments. On the 14th experimental day, 40 piglets were slaughtered to collect samples, and others 40 piglets received intramuscular injection of Escherichia coli LPS (O55:B5). For morphometric variables, in the duodenum, there was higher (P... (Complete abstract click electronic access below) / Doutor

Foram conduzidos dois experimentos com o intuito de se avaliar o desempenho, características de carcaça e parâmetros ruminais de bovinos Nelore recebendo dietas contendo grãos de milho flint processados de diferentes formas em associação a diferentes aditivos e níveis de FDN de silagem de milho (FDNf). No Experimento 1, 239 tourinhos (PCI=350±26,79kg) foram alojados em 40 baias de acordo com o peso corporal inicial e receberam dietas contendo dois tipos de processamento dos grãos de milho (moagem fina e floculação) e diferentes aditivos (monensina sódica; 25 ppm e formulação A062 a base de virginiamicina; produto teste, não comercial, fornecido pela Ourofino Saúde Animal; nas dosagens de 17 e 25 ppm), totalizando 8 tratamentos. Os dados foram analisados pelo PROC MIXED do SAS. A floculação aumentou o peso final, o ganho de peso diário, a eficiência alimentar, o peso da carcaça quente e tendeu a aumentar o rendimento de carcaça em comparação a moagem fina. Houve tendência de interação entre processamento e fornecimento de aditivos para a ingestão de matéria seca e ganho de peso diário. A floculação reduziu o teor de amido fecal, aumentou a digestibilidade do amido no trato total, aumentou os valores de energia liquida para manutenção e ganho da dieta e o numero médio de papilas ruminais. Os aditivos aumentaram a altura, largura e área das papilas e reduziram a espessura de faixa de queratina em relação ao tratamento controle. Houve tendência das formulações a base de virginiamicina aumentarem o peso da carcaça quente dos animais em comparação com a monensina sódica, mas não em relação ao tratamento controle sem aditivo. A floculação foi mais efetiva para aumentar a digestiblidade do amido no trato total, o valor energético do milho e o desempenho dos bovinos enquanto que os aditivos não foram efetivos para aumentar o valor energético das dietas e a eficiência alimentar dos animais. No Experimento 2, 237 tourinhos (PCI=350±28,49kg) foram alojados em 32 baias de acordo com o peso corporal inicial e receberam dietas contendo dois tipos de processamento (moagem grosseira e floculação) e diferentes níveis de FDNf (4; 7; 10 e 13% MS), totalizando 8 tratamentos. Os dados foram analisados pelo PROC MIXED do SAS. A floculação tendeu a aumentar a eficiência alimentar, o peso da carcaça quente e a espessura de gordura subcutânea, reduziu o teor de amido fecal, aumentou a digestibilidade do amido no trato total como também aumentou os valores de energia liquida para manutenção e para ganho das dietas. Os níveis de FDNf afetaram ingestão de matéria seca e o peso da carcaça quente independente do método de processamento. Houve tendência de aumento linear no GPD e tendência de redução quadrática na eficiência alimentar com inclusão crescente de FDNf. A inclusão de silagem de milho em dietas com alto teor de milho flint reduziu a eficiência alimentar dos animais, mas aumentou o peso da carcaça quente. A floculação aumentou o valor energético do cereal para tourinhos Nelore em dietas com alto teor de energia. / Two experiments were conducted to evaluate animal performace, carcass characteristics and ruminal parameters of Nellore bulls fed with diets containing flint corn processed by different methods in association with additives and FDN levels of corn silage (FDNf).In the first experiment, two hundred and trhirty nine Nellore bulls (IBW=350±26.79kg) were blocked based on their initial body weight and randomly divided into 40 pens. The objective was to evaluate two different corn processing methods (fine ground and steam-flaked corn) and additives (monensin; 25 ppm and A062 formulation based on virginiamycin; test product, non-commercial, provided by Ourofino Saude Animal; 17 or 25 ppm), a total of 8 treatments. Data were analyzed using PROC MIXED of SAS. Steam-flaking increased the final body weight, average daily gain, feed efficiency, hot carcass weight and tended to increase the carcass yield. There was a tendency of interaction between corn processing and feed additives for dry matter intake and daily weight gain. Steam-flaking decreased fecal starch, increased total tract starch digestibility and increased net energy for maintenance and net energy for gain values of the diet and increased average number of papillae. Additives increased papillae leight, width, and area and decreased keratin strip thickness in comparison to the control diet. There was a tendency of A062 formulations based on virginiamycin to increase hot carcass weight in comparison to monensin, but not in relation to the control treatment, without additive. Steam-flaking was more effective to increase total tract starch digestibility, corn energy values and animal performace while the feed additives were not effective to increase the net energy value of the diets and animal feed efficiency. In the second experiment, two hundred and thirty seven Nellore bulls (IBW=350±28.49kg) were blocked based on their initial body weight and randomly divided into 32 pens. The objective was to evaluate two different corn processing methods (ground and steam-flaked corn) and four FDNf levels (4; 7; 10; 13 %DM), a total of 8 treatments. Data were analyzed using PROC MIXED of SAS. Steam flaking tended to increase feed efficiency, hot carcass weight and fat thickness, decreased fecal starch, increased total tract starch digestibility and net energy for maintenance and net energy for gain diet values. Independent of corn processing, FDNf levels affected dry matter intake and hot carcass weight. There was a tendency of linear increase in daily weight gain and tendency of quadractic reduction on feed efficiency increasing FDNf levels. Corn silage in high grain diets decreased animal feed efficiency, but increased hot carcass weight. Steam-flaking increased the cereal energy value for Nellore bulls fed grain concentrate diets.

Dois experimentos foram conduzidos com o objetivo de avaliar os efeitos da inclusão de óleos essenciais (OE) extraídos das folhas e dos frutos da aroeira em dietas de alto concentrado sobre o desempenho e características de carcaça de cordeiros confinados. Experimento I: Foram utilizados 44 cordeiros, 16 machos e 28 fêmeas, sendo o delineamento experimental de blocos completos casualizados, com 4 tratamentos e 11 repetições. O experimento teve a duração de 56 dias, divididos em 2 períodos de 28 dias cada. Os animais foram alimentados com as dietas experimentais compostas por 10% de volumoso (feno de coastcross) e 90% de concentrado. Os tratamentos foram definidos pela inclusão de: 8 ppm de monensina sódica (MON) e as doses 0,140% (140 OE), 0,280% (280 OE), 0,420% (420 OE) do OE das folhas de aroeira (em % na matéria seca (MS). Ao final dos 56 dias, 31 animais foram abatidos para a mensuração dos parâmetros de carcaça. Os tratamentos não afetaram (P &gt; 0,05) o ganho de peso médio diário, consumo de matéria seca e eficiência alimentar. A infestação por coccidiose foi menor (P &lt;0,05) no tratamento com monensina. O rendimento de carcaça fria foi maior (P &lt; 0,05) nos animais alimentados com maiores doses de OE. Os demais parâmetros de carcaça avaliados não foram afetados pelos tratamentos (P &gt; 0,05). As maiores doses de OE das folhas de aroeira aumentaram (P &lt; 0,05) a porcentagem de proteína bruta e matéria mineral na composição química da carne dos cordeiros. Apesar de não alterar o desempenho dos cordeiros, a inclusão das doses mais elevadas de OE das folhas de aroeira apresentaram respostas positivas para o rendimento de carcaça fria, demonstrando o potencial de utilização desse aditivo em dietas para cordeiros confinados. Experimento II: Foram utilizados 48 cordeiros, 24 machos e 24 fêmeas, sendo o delineamento experimental de blocos completos casualizados, com 4 tratamentos e 12 repetições. O experimento teve duração de 56 dias, divididos em 2 períodos de 28 dias cada. Os animais foram alimentados com as dietas experimentais compostas por 10% de volumoso (feno de coastcross) e 90% de concentrado. Os tratamentos foram definidos pela inclusão de: 8 ppm de monensina sódica (MON) e as 11 doses 0,140% (140 OE), 0,280% (280 OE), 0,420% (420 OE) do OE dos frutos de aroeira (em % na MS). Ao final dos 56 dias, 32 animais foram abatidos para a mensuração dos parâmetros de carcaça. Não houve efeito (P &gt; 0,05) dos tratamentos no ganho de peso médio diário, consumo de matéria seca, eficiência alimentar, coccidiose e parâmetros de carcaça. A infestação por coccidiose não interferiu (P &lt; 0,05) no ganho médio diário e consumo de matéria seca. Os tratamentos com as maiores doses de OE dos frutos de aroeira reduziram o teor de matéria mineral da carne dos cordeiros em relação à monensina. O desempenho e os parâmetros de carcaça dos cordeiros alimentados com as dietas contendo OE dos frutos de aroeira foram semelhantes aos que receberam monensina sódica. / Two experiments were carried out to evaluate the effects of the inclusion of essential oils (EO) extracted from leaves and fruits of aroeira on performance and carcass characteristics of feedlot sheep fed high concentrate diets. Experiment I: Fourty-four lambs (16 males and 28 females) were assingned in a randomized complete block design to receive one of treatments: 8 ppm of sodium monensin (MON) and doses of 0.140% (140 EO), 0.280% (280 EO) and 0.420% (420 EO) of aroeira leaves EO (% in a DM basis). The experiment lasted 56 days, divided in 2 periods of 28 days each. The animals were fed a diet containing 10% roughage (coastsross hay) and 90% concentrate. At the end of experiment, 31 lambs were slaughtered to access the carcasses characteristics. The treatments did not affect (P &gt; 0.05) the average daily gain, the dry matter intake and the feed efficiency. Infestation by coccidiosis was lower (P &lt; 0.05) in the monensin treatment. Cold carcass dressing was higher (P &lt; 0.05) for the animals fed higher doses of EO. The other carcass parameters were not affected by the treatments (P &gt; 0.05). The higher doses of aroeira leaves EO increased (P &lt; 0.05) the percentage of crude protein and mineral matter in the meat. Despite did not affect the lambs performance, the inclusion of aroeira leaves EO at the higher doses did present positive results for the cold carcass dressing, showing a potential of this additive in feedlot sheep diets. Experiment II: fourty-eight lambs (24 males and 24 females) were assingned in a randomized complete block design to recive one of treatments: 8 ppm of sodium monensin (MON) and doses of 0.140% (140 EO), 0.280% (280 EO) and 0.420% (420 EO) of aroeira fruits EO (% in a DM basis). The experiment lasted 56 days, divided in 2 periods of 28 days each. The animals were fed a diet containing 10% roughage (coastsross hay) and 90% concentrate. At the end of the experiment, 32 lambs were slaughtered to access the carcasses characteristics. The treatments did not affect (P &gt; 0.05) the average daily gain, dry matter intake, feed efficiency, the coccidiosis infestation and the carcasses parameters. In addition, the infestation by coccidiosis did not interfere (P &lt; 0.05) on average daily gain and dry matter intake. The treatments with 13 higher doses of the EO from aroeira fruits reduced the percentage of mineral matter of meat compared to monensin. The performance and carcass parameters of the lambs fed diets containing essential oils were similar to those fed monensina.