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Application of resting-state fMRI methods to acute ischemic strokeLv, Yating 14 November 2013 (has links) (PDF)
Diffusion weighted imaging (DWI) and dynamic susceptibility contrast-enhanced (DSC) perfusion-weighted imaging (PWI) are commonly employed in clinical practice and in research to give pathophysiological information for patients with acute ischemic stroke. DWI is thought to roughly reflect the severely damaged infarct core, while DSC-PWI reflects the area of hypoperfusion. The volumetric difference between DWI and DSC-PWI is termed the PWI/DWI-mismatch, and has been suggested as an MRI surrogate of the ischemic penumbra. However, due to the application of a contrast agent, which has potentially severe side-effects (e.g., nephrogenic systemic fibrosis), the DSC-PWI precludes repetitive examinations for monitoring purposes. New approaches are being sought to overcome this shortcoming.
BOLD (blood oxygen-level dependent) signal can reflect the metabolism of blood oxygen in the brain and hemodynamics can be assessed with resting-state fMRI. The aim of this thesis was to use resting-state fMRI as a new approach to give similar information as DSC-PWI. This thesis comprises two studies:
In the first study (see Chapter 2), two resting-state fMRI methods, local methods which compare low frequency amplitudes between two hemispheres and a k-means clustering approach, were applied to investigate the functional damage of patients with acute ischemic stroke both in the time domain and frequency domain. We found that the lesion areas had lower amplitudes than contralateral homotopic healthy tissues. We also differentiated the lesion areas from healthy tissues using a k-means clustering approach.
In the second study (see Chapter 3), time-shift analysis (TSA), which assesses time delays of the spontaneous low frequency fluctuations of the resting-state BOLD signal, was applied to give similar pathophysiological information as DSC-PWI in the acute phase of stroke. We found that areas which showed a pronounced time delay to the respective mean time course were very similar to the hypoperfusion area.
In summary, we suggest that the resting-state fMRI methods, especially the time-shift analysis (TSA), may provide comparable information to DSC-PWI and thus serve as a useful diagnostic tool for stroke MRI without the need for the application of a contrast agent.
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Counter-stories of First-Generation Latinx Alumnae: A Critical Race Theory AnalysisEzell, Pamela 18 May 2018 (has links)
This study includes the experiences of six first-generation Latinx alumnae who attended three private, predominantly-White universities in Southern California. It applied a critical race theory (CRT) framework and an anti-deficit ideology to their experiences. Importantly, because the participants and the researcher are of different identities, the study employed principles of culturally responsive methodologies (CRM). Most quantitative research and existent theory concerning first-generation Latinx collegiate women excludes the voices of first-generation Latinx alumnae, so this study included the telling of their counter-stories concerning their undergraduate experiences. These experiences included identity-threat, microaggressions, and the enactment of White privilege. Additionally, their counter-stories contradict majoritarian stories concerning first-generation students and their families, as well as institutional values of fairness, meritocracy, colorblindness, and diversity. The methodology of the study was CRT counter-storytelling. Concepts of narrative inquiry informed the research design. Counter-stories of the participants were shared during conversations and interviews, then interpreted using the framework of CRT and a method of thematic analysis. All members of the study have graduated with a bachelor’s degree, and their experiences provide direction for additional research concerning first-generation theory as it applies to Latinx collegiate women, as well as implications for policy and praxis regarding the future experiences of Latinx students on U.S. higher education campuses.
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Exploring Influences on Black Student Study Abroad ParticipationHartkopf, Stephanie 01 January 2020 (has links) (PDF)
The purpose of this case study was to explore the factors that influence Black students' decisions to participate in study abroad programs. This study took place at a large, public, Predominantly White Institution in the southeastern United States. Three theories formed a conceptual framework to guide this study, including Critical Race Theory, Theory of Planed Behavior, and Astin's Input-Environment-Output Model. Semi-structured interviews were conducted with 5 Black study abroad alumni, which revealed 6 themes of influential factors in making decisions to participate in study abroad: (a) familiarity, (b) finance, (c) family, (d) faculty, (e) fear, and (f) finish.
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A Fly in Milk: The Urban Black Experience at a Rural White InstitutionSanders, Stephanie L. 26 July 2012 (has links)
No description available.
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Relação entre o bem-estar subjetivo de pais e filhos adolescentes a partir de diferentes medidas de avaliaçãoBedin, Lívia Maria January 2013 (has links)
Esta tese tem como objetivos verificar as propriedades psicométricas dos instrumentos de bem-estar: Personal Wellbeing Index (PWI), Satisfaction With Life Scale (SWLS), Brief Multidimensional Students’ Life Satisfaction Scale (BMSLSS) e Core Affects Scale (CAS); apresentar o bem-estar nos grupos de pais e filhos adolescentes; e verificar a relação entre o bem-estar subjetivo de pais e seus filhos adolescentes a partir de diferentes medidas de avaliação. Foram realizados três estudos, com 543 adolescentes com idades entre 12 e 16 anos (68,3% meninas) e seus respectivos pais, com idade média aproximada de 44 anos. Os resultados apontam que o PWI e as escalas SWLS, BMSLSS e CAS apresentam, no geral, bons índices de ajuste quando da realização da análise fatorial (exploratória e confirmatória) para a amostra de adolescentes e para a de pais. Verificam-se diferenças significativas entre as médias de diferentes domínios de bem-estar, sendo as médias mais altas para os adolescentes do que para os pais. Com relação às diferenças por sexo, para as medidas de bem-estar globais observa-se que tanto as meninas como as mães apresentam médias mais baixas do que os meninos e os pais. Não foram encontradas diferenças significativas por idade para os adolescentes e para os pais, apesar de haver uma diminuição nas médias de diversas medidas para os adolescentes com o aumento dos 12 aos 16 anos. Houve diferenças para classe social, sendo as médias de bem-estar mais baixas para os participantes de classe média baixa. Especificamente, há diferenças entre a interação de classe social e sexo, e as participantes do sexo feminino de classe média baixa apresentam as menores médias de bem-estar. Finalmente, a relação entre o bem-estar de pais e filhos foi analisada, chegando-se a 5 itens que apresentam correlação de 0,41 entre pais e filhos: a satisfação com a família, com o lugar onde vive, com as condições onde vive, com o nível de vida e com a segurança, formando uma dimensão denominada de satisfação com o microssistema. Os resultados para os modelos de interdependência ator-parceiro (APIM) apresentam efeitos significativos entre a satisfação e a felicidade global com a vida dos pais e o bem-estar dos filhos adolescentes, apesar de pequenos. / This thesis aims to examine the psychometric properties of the well-being instruments: Personal Wellbeing Index (PWI), Satisfaction With Life Scale (SWLS), Brief Multidimensional Students’ Life Satisfaction Scale (BMSLSS) and Core Affects Scale (CAS); to present the well-being in the groups of parents and children, and to verify the relation of the subjective well-being of parents and their adolescent children using different assessment measures. Three studies were conducted with 543 adolescents aged between 12 and 16 years (68.3% girls) and their respective parents with an average age of approximately 44 years. The main results show that the scales SWLS, PWI, BMSLSS and CAS have good overall fit indices when performing factor analysis (exploratory and confirmatory) for the sample of adolescents and parents. There are significant differences between the averages of different well-being domains and the averages are higher for teenagers than for parents mostly. With respect to gender differences, for some of the measures of well-being it is observed that girls as mothers present lower average than boys and parents. Considering age, in general there were no significant differences found for adolescents and parents, despite a decrease in the mean for several measures for adolescents when increasing age. There were differences in social class, and the means of well-being are lower for participants from lower middle class. Specifically, there are differences between the interaction of social class and gender, and female participants from lower middle class have lower average well-being. Finally, the relationship between the well-being of parents and children was analyzed, reaching up to 5 items that show a correlation of 0.41 between parents and children: satisfaction with family, where you live, with the conditions of where you live, with the standard of living and security, forming a dimension called satisfaction with the microsystem. The results for the actor-partner interdependence model (APIM) show significant effects between the overall satisfaction and happiness with life of parents and the well-being of adolescent children, though small.
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Relação entre o bem-estar subjetivo de pais e filhos adolescentes a partir de diferentes medidas de avaliaçãoBedin, Lívia Maria January 2013 (has links)
Esta tese tem como objetivos verificar as propriedades psicométricas dos instrumentos de bem-estar: Personal Wellbeing Index (PWI), Satisfaction With Life Scale (SWLS), Brief Multidimensional Students’ Life Satisfaction Scale (BMSLSS) e Core Affects Scale (CAS); apresentar o bem-estar nos grupos de pais e filhos adolescentes; e verificar a relação entre o bem-estar subjetivo de pais e seus filhos adolescentes a partir de diferentes medidas de avaliação. Foram realizados três estudos, com 543 adolescentes com idades entre 12 e 16 anos (68,3% meninas) e seus respectivos pais, com idade média aproximada de 44 anos. Os resultados apontam que o PWI e as escalas SWLS, BMSLSS e CAS apresentam, no geral, bons índices de ajuste quando da realização da análise fatorial (exploratória e confirmatória) para a amostra de adolescentes e para a de pais. Verificam-se diferenças significativas entre as médias de diferentes domínios de bem-estar, sendo as médias mais altas para os adolescentes do que para os pais. Com relação às diferenças por sexo, para as medidas de bem-estar globais observa-se que tanto as meninas como as mães apresentam médias mais baixas do que os meninos e os pais. Não foram encontradas diferenças significativas por idade para os adolescentes e para os pais, apesar de haver uma diminuição nas médias de diversas medidas para os adolescentes com o aumento dos 12 aos 16 anos. Houve diferenças para classe social, sendo as médias de bem-estar mais baixas para os participantes de classe média baixa. Especificamente, há diferenças entre a interação de classe social e sexo, e as participantes do sexo feminino de classe média baixa apresentam as menores médias de bem-estar. Finalmente, a relação entre o bem-estar de pais e filhos foi analisada, chegando-se a 5 itens que apresentam correlação de 0,41 entre pais e filhos: a satisfação com a família, com o lugar onde vive, com as condições onde vive, com o nível de vida e com a segurança, formando uma dimensão denominada de satisfação com o microssistema. Os resultados para os modelos de interdependência ator-parceiro (APIM) apresentam efeitos significativos entre a satisfação e a felicidade global com a vida dos pais e o bem-estar dos filhos adolescentes, apesar de pequenos. / This thesis aims to examine the psychometric properties of the well-being instruments: Personal Wellbeing Index (PWI), Satisfaction With Life Scale (SWLS), Brief Multidimensional Students’ Life Satisfaction Scale (BMSLSS) and Core Affects Scale (CAS); to present the well-being in the groups of parents and children, and to verify the relation of the subjective well-being of parents and their adolescent children using different assessment measures. Three studies were conducted with 543 adolescents aged between 12 and 16 years (68.3% girls) and their respective parents with an average age of approximately 44 years. The main results show that the scales SWLS, PWI, BMSLSS and CAS have good overall fit indices when performing factor analysis (exploratory and confirmatory) for the sample of adolescents and parents. There are significant differences between the averages of different well-being domains and the averages are higher for teenagers than for parents mostly. With respect to gender differences, for some of the measures of well-being it is observed that girls as mothers present lower average than boys and parents. Considering age, in general there were no significant differences found for adolescents and parents, despite a decrease in the mean for several measures for adolescents when increasing age. There were differences in social class, and the means of well-being are lower for participants from lower middle class. Specifically, there are differences between the interaction of social class and gender, and female participants from lower middle class have lower average well-being. Finally, the relationship between the well-being of parents and children was analyzed, reaching up to 5 items that show a correlation of 0.41 between parents and children: satisfaction with family, where you live, with the conditions of where you live, with the standard of living and security, forming a dimension called satisfaction with the microsystem. The results for the actor-partner interdependence model (APIM) show significant effects between the overall satisfaction and happiness with life of parents and the well-being of adolescent children, though small.
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Relação entre o bem-estar subjetivo de pais e filhos adolescentes a partir de diferentes medidas de avaliaçãoBedin, Lívia Maria January 2013 (has links)
Esta tese tem como objetivos verificar as propriedades psicométricas dos instrumentos de bem-estar: Personal Wellbeing Index (PWI), Satisfaction With Life Scale (SWLS), Brief Multidimensional Students’ Life Satisfaction Scale (BMSLSS) e Core Affects Scale (CAS); apresentar o bem-estar nos grupos de pais e filhos adolescentes; e verificar a relação entre o bem-estar subjetivo de pais e seus filhos adolescentes a partir de diferentes medidas de avaliação. Foram realizados três estudos, com 543 adolescentes com idades entre 12 e 16 anos (68,3% meninas) e seus respectivos pais, com idade média aproximada de 44 anos. Os resultados apontam que o PWI e as escalas SWLS, BMSLSS e CAS apresentam, no geral, bons índices de ajuste quando da realização da análise fatorial (exploratória e confirmatória) para a amostra de adolescentes e para a de pais. Verificam-se diferenças significativas entre as médias de diferentes domínios de bem-estar, sendo as médias mais altas para os adolescentes do que para os pais. Com relação às diferenças por sexo, para as medidas de bem-estar globais observa-se que tanto as meninas como as mães apresentam médias mais baixas do que os meninos e os pais. Não foram encontradas diferenças significativas por idade para os adolescentes e para os pais, apesar de haver uma diminuição nas médias de diversas medidas para os adolescentes com o aumento dos 12 aos 16 anos. Houve diferenças para classe social, sendo as médias de bem-estar mais baixas para os participantes de classe média baixa. Especificamente, há diferenças entre a interação de classe social e sexo, e as participantes do sexo feminino de classe média baixa apresentam as menores médias de bem-estar. Finalmente, a relação entre o bem-estar de pais e filhos foi analisada, chegando-se a 5 itens que apresentam correlação de 0,41 entre pais e filhos: a satisfação com a família, com o lugar onde vive, com as condições onde vive, com o nível de vida e com a segurança, formando uma dimensão denominada de satisfação com o microssistema. Os resultados para os modelos de interdependência ator-parceiro (APIM) apresentam efeitos significativos entre a satisfação e a felicidade global com a vida dos pais e o bem-estar dos filhos adolescentes, apesar de pequenos. / This thesis aims to examine the psychometric properties of the well-being instruments: Personal Wellbeing Index (PWI), Satisfaction With Life Scale (SWLS), Brief Multidimensional Students’ Life Satisfaction Scale (BMSLSS) and Core Affects Scale (CAS); to present the well-being in the groups of parents and children, and to verify the relation of the subjective well-being of parents and their adolescent children using different assessment measures. Three studies were conducted with 543 adolescents aged between 12 and 16 years (68.3% girls) and their respective parents with an average age of approximately 44 years. The main results show that the scales SWLS, PWI, BMSLSS and CAS have good overall fit indices when performing factor analysis (exploratory and confirmatory) for the sample of adolescents and parents. There are significant differences between the averages of different well-being domains and the averages are higher for teenagers than for parents mostly. With respect to gender differences, for some of the measures of well-being it is observed that girls as mothers present lower average than boys and parents. Considering age, in general there were no significant differences found for adolescents and parents, despite a decrease in the mean for several measures for adolescents when increasing age. There were differences in social class, and the means of well-being are lower for participants from lower middle class. Specifically, there are differences between the interaction of social class and gender, and female participants from lower middle class have lower average well-being. Finally, the relationship between the well-being of parents and children was analyzed, reaching up to 5 items that show a correlation of 0.41 between parents and children: satisfaction with family, where you live, with the conditions of where you live, with the standard of living and security, forming a dimension called satisfaction with the microsystem. The results for the actor-partner interdependence model (APIM) show significant effects between the overall satisfaction and happiness with life of parents and the well-being of adolescent children, though small.
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Application of resting-state fMRI methods to acute ischemic strokeLv, Yating 26 September 2013 (has links)
Diffusion weighted imaging (DWI) and dynamic susceptibility contrast-enhanced (DSC) perfusion-weighted imaging (PWI) are commonly employed in clinical practice and in research to give pathophysiological information for patients with acute ischemic stroke. DWI is thought to roughly reflect the severely damaged infarct core, while DSC-PWI reflects the area of hypoperfusion. The volumetric difference between DWI and DSC-PWI is termed the PWI/DWI-mismatch, and has been suggested as an MRI surrogate of the ischemic penumbra. However, due to the application of a contrast agent, which has potentially severe side-effects (e.g., nephrogenic systemic fibrosis), the DSC-PWI precludes repetitive examinations for monitoring purposes. New approaches are being sought to overcome this shortcoming.
BOLD (blood oxygen-level dependent) signal can reflect the metabolism of blood oxygen in the brain and hemodynamics can be assessed with resting-state fMRI. The aim of this thesis was to use resting-state fMRI as a new approach to give similar information as DSC-PWI. This thesis comprises two studies:
In the first study (see Chapter 2), two resting-state fMRI methods, local methods which compare low frequency amplitudes between two hemispheres and a k-means clustering approach, were applied to investigate the functional damage of patients with acute ischemic stroke both in the time domain and frequency domain. We found that the lesion areas had lower amplitudes than contralateral homotopic healthy tissues. We also differentiated the lesion areas from healthy tissues using a k-means clustering approach.
In the second study (see Chapter 3), time-shift analysis (TSA), which assesses time delays of the spontaneous low frequency fluctuations of the resting-state BOLD signal, was applied to give similar pathophysiological information as DSC-PWI in the acute phase of stroke. We found that areas which showed a pronounced time delay to the respective mean time course were very similar to the hypoperfusion area.
In summary, we suggest that the resting-state fMRI methods, especially the time-shift analysis (TSA), may provide comparable information to DSC-PWI and thus serve as a useful diagnostic tool for stroke MRI without the need for the application of a contrast agent.
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Opravy DPS s BGA a FC pouzdry / PCBs Repairs with BGA and FC PackagesBuřival, Tomáš January 2009 (has links)
Graduation thesis is specialized on dilemma of the integrated circuits with ball grid array. Chapter two describes several types of packages and confrontation of their characteristics. Chapter three considers possibilities of corrections these boards bedded with packages, mounting and demounting of these packages, method of camera control and also inspection of the soldering process. Chapter four attend to practical measuring of thermal profiles and their optimalization.
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Skinfolk & Kinfolk: Social Capital, Fictive Kin, and Persistence Among Black Students at a Predominately White InstitutionCarson, Kerra Selekah January 2022 (has links)
No description available.
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