This Thesis is an exploration of white fathers in three post-apartheid novels: Mark Behr's The Smell of Apples, Nadine Gordimer's The House Gun, and J. M. Coetzee's Disgrace. By examining the link between private white hegemonic masculinity and the apartheid government, the Thesis analyzes the transitional process as these men try to adopt less authoritative identities.

Thesis (Msc Food Sc (Food Science))--University of Stellenbosch, 2006. / The food and beverage industry generates large volumes of wastewater annually. The disposal of factory effluent from the fruit processing industry has always been a cause of concern to both the fruit processors and controlling bodies responsible for effluent management. Traditional disposal of wastewater into sewerage works has become undesirable due to its economical and environmental impacts. Therefore, on-site anaerobic treatment of wastewater has received considerable interest due to lower capital outlays and energy recovery possibilities. Thus, the aim of this study was to establish an operational treatment profile for an anaerobic pond system treating fruit-processing wastewater. The specific activity of the microbial populations was also monitored to determine the effect of the fruit processing seasons (peak and off-peak season). The biogas production potential at various temperatures was also assessed to determine the viability of methane recovery. The influence of the processing and environmental conditions on the ponds’ performance was established by monitoring various process parameters. The results showed that the chemical oxygen demand (COD) levels decreased during the off-peak season but the pond pH remained relatively stable between 6.0 and 6.4 during the entire year. Pond alkalinity was found to be dependent on the regular lime dosing to maintain the necessary alkalinity. The volatile fatty acid (VFA) concentrations indicated that the microbial populations of the pond were functioning well. However, a decrease in microbial activity and VFA concentrations were observed at the lower temperatures during the winter months. The temperature profile of the pond showed that the pond temperature was impacted by the fluctuations in the ambient air temperature. The general trend established by the operational treatment profile clearly showed the impact of the peak and off-peak season. The sludge activity of the anaerobic pond was evaluated to determine the effect of the apple-processing peak and off-peak season on the specific activity of the acidogenic and methanogenic populations within the sludge. An activity test using four different test media was used during the activity assays. Sludge samples were taken at four different sampling positions across the pond’s sludge bed. The sludge was also subjected to a biogas formation study, which was designed to simulate pond conditions on laboratory scale in order to evaluate the biogas production potential of the anaerobic pond. The cumulative biogas volume and total CH4 composition showed little or no difference between the four sludge sampling sites. A major difference was found between the activity of the microbial populations during the peak and off-peak seasons. The overall trend regarding the biogas production rate (SB) and the methane production rate (SM) values showed an increased activity during peak-season and a decreased activity during off-peak season. For the biogas formation test the highest incubation temperature (25°C) resulted in the most biogas being produced, followed by 18°C, and with 10°C resulting in the lowest biogas volume. The biogas formation tests indicated that microbial activity and therefore biogas production was dependent on especially favourable temperature conditions. The pond and activity of the microbial populations are therefore influenced by factors like environmental changes such as decreased air temperatures and substrate changes such as decreased COD concentrations during the off-peak season. This in turn influences the rate of biogas production as well as the methane production rate. The theoretical CH4 calculations and estimates based on the results obtained during the biogas formation tests indicated that CH4 recovery from the anaerobic pond would definitely be a worthwhile consideration. If it were assumed that the estimated CH4 volumes (based on only 15% of the pond volume for practical reasons) obtained could be applied as an energy source, the minimum yearly savings in coal usage would amount to about R 665 000. This study was valuable in evaluating the factors such as pond conditions, pond activity and air temperatures and the effect on the biogas production potential as well as more importantly, CH4 production for the purpose of energy recovery.

Thesis (MscAgric (Horticulture))--University of Stellenbosch, 2008. / ‘Brookfield Gala’ apple trees were planted out in July 2003 in a Dundee soil form, consisting of well-aerated sandy loam soil. During the first 12 months trees received young tree solutions high in nitrogen. The nutrient solution of the 2nd leaf trees was based on a yield estimation of 10 ton. ha-1 plus 30%. Nutrient solutions for the 3rd leaf trees were based on 25 ton. ha-1 yield estimations and adapted upwards. Seasonal uptake and distributions were determined for macro and micro elements, using twoand three-year-old apple trees during the seasons 2004/2005 and 2005/2006. In the bearing apple trees the macro nutrient accumulated rapidly from late winter to late autumn. Prior to leaf drop most of the N, P, S, Mg and a small portion of K were redistributed back into the permanent parts of the tree. On the other hand, all Ca in the leaves was lost through leaf drop. Apple fruit contains comparatively large quantities (±60.2%) of K, which are removed during harvest. Guidelines for minimum and maximum nutritional requirements based on the amount necessary to produce 1 kg fruit were determined. For the 3rd leaf trees the minimum macro nutrient requirements (g. kg-1 yield) of N, P, K, Ca, Mg and S were ±1.7, ±0.3, ±2.3, ±0.5, ±0.2 and ±0.2, respectively. The maximum nutrient requirements (g. kg-1 yield) for N, P, K, Ca, Mg and S were ±2.6, ±0.4, ±3.3, ±1.9, ±0.4 and ±0.2, respectively. For the 3rd leaf trees the minimum micro nutrient requirements (mg. kg-1 yield) of Na, Mn, Fe, Cu, Zn, B and Mo were ±75.1, ±1.3, ±28.7, ±0.9, ±3.0, ±5.7 and ±0.3, respectively. The maximum nutrient requirements (mg. kg-1 yield) of Na, Mn, Fe, Cu, Zn, B and Mo were ±102.9, ±7.8, ±32.6, ±1.1, ±6.5, ±7.6 and ±0.3, respectively. Labelled N uptake and distribution for two- and three-year-old apple trees were also determined during the same seasons. The labelled N uptake and distribution results indicated that there was a low labelled N uptake in the initial growth stages, suggesting the importance of internal N reserves for plant development at the beginning of the season. In the active growing period more than 60% of the labelled N was found in the new growth. Uptake efficiency improved as the trees grew older. The effect of different nutrient levels on tree growth, yield and fruit quality was assessed: lower (80%) than the standard (100%) and three higher (120%, 140% and 160%). Results indicated that different nutrient levels had no effect on yield, blush or TSS during the 18 months of application over two bearing seasons. The application of biological products (humic acid, and compost plus compost extract) over a period of 18 months had a significant influence on the TSS, malic acid and citric acid concentrations. A tendency towards an increase in total fine root number and length occured with the addition of biological ameliorant.

A realidade das organizações atualmente faz com que os desafios apresentados sejam enfrentados procurando-se a maior eficácia para suas soluções e com isso surjam as adaptações necessárias as constantes mudanças de maneira que os entraves sejam solucionados levando em consideração toda a amplitude que apresentarem. A Teoria da Complexidade por sua essência pode propiciar uma visão mais próxima da realidade, auxiliando na busca pelo entendimento de processos relacionados a gestão dos sistemas. Essa abordagem pode proporcionar uma maior efetividade nas ações das organizações, podendo servir de suporte para o melhor entendimento dos relacionamentos e das necessidades dos atores tanto internos como dos atores externos envolvidos nas organizações. Este trabalho foi construído a partir da necessidade do entendimento de como acontecem os relacionamentos entre os integrantes da cadeia produtiva da maçã para a partir disso propor mecanismos que possam auxiliar na melhoria das inter-relações. Assim, utilizou-se a abordagem do anel tetralógico para auxiliar na identificação das ações decorrentes da implementação da PIM na cadeia produtiva da maçã nos estados do Rio Grande do Sul e Santa Catarina. Trata-se de uma pesquisa qualitativa, operacionalizada através de um estudo de caso. Para que os objetivos fossem atingidos foi realizada uma revisão teórica a cerca dos pilares que sustentam o estudo, cadeia produtiva, relacionamento e teoria da Complexidade. Baseando-se na revisão teórica foram construídos os procedimentos metodológicos para a coleta e análise dos dados. A realização do estudo de caso realizou-se a partir de entrevistas com especialistas integrantes da cadeia produtiva da maçã brasileira. A análise dos dados proporcionou a evidencia de resultados como: identificação dos conceitos do anel tetralógico na implementação da Produção Integrada de Maçã; verificação das estratégias que a cadeia produtiva da maçã utiliza como norteadores do sistema; presença nos relacionamentos de ações e atitudes que trazem ao sistema a necessidade de trabalho voltado para o comportamento de cooperação e trabalho em equipe; além da necessidade de uma reorganização voltada para o cumprimento dos processos de certificação por parte do elo compradores atacadistas e varejistas, assim como a conscientização dos consumidores finais para a exigência de controle de qualidade no momento da compra. / Submitted by Marcelo Teixeira (mvteixeira@ucs.br) on 2014-05-28T19:54:25Z No. of bitstreams: 1 Dissertacao Marcia Rohr da Cuz.pdf: 556190 bytes, checksum: a8d9e8fb44293b0763108a51bc83715c (MD5) / Made available in DSpace on 2014-05-28T19:54:25Z (GMT). No. of bitstreams: 1 Dissertacao Marcia Rohr da Cuz.pdf: 556190 bytes, checksum: a8d9e8fb44293b0763108a51bc83715c (MD5) / The reality of the organizations at present does so that the presented challenges are faced looking for the biggest efficiency for his solutions and the necessary adaptations appear for the constant changes so that the hamper are solved taking into account the whole breadth what to present. The Theory of the Complexity for his essence can give a vision more near the reality, helping in the search for the understanding of processes related of the systems of management. This approach can provide a bigger effectiveness in the actions of the organizations, being able to serve of support for the best understanding of the relationships and of the necessities of the actors so the internal as the external actors wrapped in the organizations. This work was fulfilled from the necessity of the understanding of how the relationships happen between the integrants of the productive chain of the apple for from that to propose mechanisms that could help in the improvement of the inter-relations. So, there was suggested the use of the approach of the tetralogic ring for help in the identification of the actions resulting from the implementation of the PIM in the productive chain of the apple in the states of Rio Grande do Sul and Santa Catarina. So that the objectives being reached it was carried out a theoretical revision around the pillars that support the study, productive chain, relationship and theory of the Complexity. Being based on the theoretical revision there was built proceedings for the collection and analysis of the data. The realization of the study case happened from interviews with specialists, integrant of the productive chain of the Brazilian apple. The analysis of the data provided shows up of results like: identification of the concepts of the tetralógic ring in the implementation of the Integrated Production of Apple; checking of the strategies that the productive chain of the apple uses how direction of the system; presence in the relationships of actions and attitudes that bring to the system the necessity of work turned to the behavior of cooperation and work in team; besides the necessity of a reorganization turned to the fulfillment of the processes of certification for part of the link wholesale and retail buyers, as well as the conscience of the final consumers for the demand of quality control at the moment of the purchase.

As crescentes exigências por qualidade e demanda a alimentos seguros pressionam as cadeias agroalimentares, para que adotem sistemas produtivos alternativos, e que estes gerem produtos saudáveis e inócuos ao consumo humano, por meio de práticas rastreáveis, visando à proteção do meio ambiente, dos trabalhadores e dos consumidores. A Produção Integrada de Maçã (PIM) surgiu como uma resposta a essas exigências, atuando como uma ferramenta de padronização da produção dessa fruta. A partir disso, o trabalho verificou se a adoção da PIM, na cadeia produtiva de maçã, é suficiente para que esse produto não esteja sujeito a barreiras técnicas e não tarifárias do mercado externo. Para isso, foram pesquisadas quais certificações para maçã são mais relevantes aos mercados consumidores, buscando identificar e classificar os requisitos e qual o posicionamento da PIM perante essas regulamentações. Para tanto, foi desenvolvido um estudo exploratório, por meio de pesquisa bibliográfica, documental e de levantamento dentro da PIM, pelo qual foi possível identificar que necessidade de ajustes para que esse programa mantenha sua relevância como certificação na cadeia produtiva da maçã, pois não possui a equiparação aos selos internacionais, necessária para sua aceitação no Exterior e nem conhecimento no mercado nacional. / Submitted by Marcelo Teixeira (mvteixeira@ucs.br) on 2014-06-02T18:57:08Z No. of bitstreams: 1 Dissertacao Silvio Denicol Junior.pdf: 1100744 bytes, checksum: ffcadba9984f99401a9e1e8a0906c94e (MD5) / Made available in DSpace on 2014-06-02T18:57:08Z (GMT). No. of bitstreams: 1 Dissertacao Silvio Denicol Junior.pdf: 1100744 bytes, checksum: ffcadba9984f99401a9e1e8a0906c94e (MD5) / The increasing demand for quality and safe food is been pushing the agri-food chains to adopt alternative production systems, with the purpose of generate healthy and innocuous products for human consumption through traceable practices, in order to protect the environment, workers and consumer. The integrated apple production (PIM) has emerged as a response to these requirements, serving as a tool to standardize the production of this fruit. From this, the study examined whether the adoption of pim in apple production chain, it is enough to avoid that this product being a subject for technical and non-tariff barriers in the foreign market. Considering this, it was researched which apple certifications are more relevant to the consumer markets, looking for identifying and classifying the requirements and also which is the positioning of the pim considering this kind of regulations. Therefore, was developted an exploratory study, through a bibliografic, documental and survey research inside the PIM, from which it was possible identify that the PIM requires adjustments to maintain its relevance as a certification in the apple productive chain, because it still does not have the equalization to the international labels, that is required to its acceptance on abroad, or even the recognition in the domestic market

O contexto da globalização é um processo evolutivo da sociedade, aliado a outros fatores que impõem às empresas a formação de diferentes arranjos, na busca de se manterem no mercado competitivo. As mudanças, nesse cenário mundial, dificultam as condições de sobrevivência das empresas, obrigando as mesmas a estabelecerem relações cooperativas, com vistas a obter os fatores de produção necessários à sua manutenção nos mercados. No que se refere à cadeia produtiva da maçã, objeto deste estudo, a área cultivada no mundo vem decrescendo desde 1996. Entretanto, na América do Sul, observa-se uma tendência crescente de incremento de área cultivada. A pesquisa teve como objetivo avaliar o desempenho competitivo da cadeia produtiva de maçã na Região Sul do Brasil, tendo como referência os maiores produtores dos Estados de Santa Catarina (SC), Rio Grande do Sul (RS) e Paraná (PR). O estudo utilizou como embasamento teórico a Teoria dos Sistemas, Cadeia Produtiva, Diagnóstico da Cadeia Produtiva, Desempenho da Cadeia Produtiva e, por fim, Indicadores de Desempenho de qualidade, eficiência, equidade, sustentabilidade e competitividade da cadeia. Para atingir os objetivos, a pesquisa foi do tipo qualitativa, com caráter exploratório e operacionalizado mediante um de estudo de caso. A coleta de dados foi realizada por meio de entrevistas em profundidade, semiestruturadas aos elos da cadeia produtiva da maçã, ou seja, os fornecedores de insumos, o produtor, o packing house e o distribuidor, bem como os especialistas, totalizando 26 agentes da CPM, escolhidos por conveniência. Mediante análise dos dados, ficou evidenciado que há vários fatores negativos e positivos que impactam a cadeia. Os pontos negativos foram: falta de organização, falta divulgação, mão de obra não qualificada e com custo alto, excesso de burocracia dos agentes financeiros, deficiência de capital, pulverização excessiva da oferta, não há relacionamento entre os elos da CPM. Entre outros, dos pontos positivos, destaca-se a utilização de tecnologia avançada no packing house, no porta-enxerto; a utilização da certificação como a Globalgap. Também detectou-se preocupação com a questão ambiental e social. / Submitted by Marcelo Teixeira (mvteixeira@ucs.br) on 2014-06-02T19:36:58Z No. of bitstreams: 1 Dissertacao Marta Elisete Ventura da Motta.pdf: 919297 bytes, checksum: 514ea3d6d0dabce19494b405b2486d27 (MD5) / Made available in DSpace on 2014-06-02T19:36:58Z (GMT). No. of bitstreams: 1 Dissertacao Marta Elisete Ventura da Motta.pdf: 919297 bytes, checksum: 514ea3d6d0dabce19494b405b2486d27 (MD5) / The context of globalization is an evolutionary process of society, together with other factors that require the companies to form different arrangements, seeking to remain competitive in the market. The changes in this global scenario, difficult conditions for the survival of companies, forcing them to establish cooperative relationships in order to obtain the factors of production necessary to maintain the markets. With regard to the productive chain of the apple, the object of this study, the cultivated area in the world has been falling since 1996. However, in South America, there is a growing tendency for increases in area cultivated. The research aimed to assess the competitive performance of the productive chain of the apple in the South of Brazil, with reference to the major producers of the States of Santa Catarina (SC), Rio Grande do Sul (RS) and Paraná (PR). The study used as the theoretical foundation of systems theory, productive chain, productive chain diagnostics, performance of the productive chain, performance Iidicators order to base the assessment of quality, efficiency, equity, sustainability and competitiveness of the chain. To achieve the objectives the methodology was a qualitative study, exploratory and operationalized through a case study. As a tool for data collection were conducted through interviews in depth semi-structured to the productive chain of the apple and the suppliers of inputs, producer, packing house and distributors, as well as specialists, totaling 26 agents CPM, chosen by convenience. By analyzing the data it was evident that there are several factors that impact both positive and negative chain. The negative points were lack of organization, poor disclosure, unskilled labor and high cost, excessive bureaucracy of financial agents, the deficiency of capital, spraying too much supply, there is no relationship between the links of the CPM. Among the positive highlights the use of advanced technology in the packing house, the rootstock, using certified as Globalgap. Also detected the concern about the environmental and social.

The high composition of fruits and vegetables in the daily diet is associated with cognitive well-being, especially in the elderly population. The phytonutrients are shown to have effects as antioxidants that neutralize oxidative stressors and can interact with molecular pathways to signal neuron survival. Adult hippocampal neurogenesis is a dynamic lifelong process of generating functional newborn neurons in the granular layer of the dentate gyrus from adult precursor cells. This process contributes to brain plasticity and plays a role in learning and memory. External stimuli such as environmental enrichment and physical activity are known to positively regulate this process. However, the role of nutrition and whether nutritional compounds have pro-neurogenic effects on adult hippocampal precursor cells are still elusive. In this study, I investigated the impact of dietary compounds in apples, a significant source of phytonutrients in our food, on adult hippocampal neurogenesis. I demonstrated that quercetin, the most abundant polyphenol in apple, induces cell cycle exit and differentiation of adult hippocampal precursor cells in monolayer culture. Furthermore, this compound also increases the number of surviving cells upon differentiation in vitro, through the activation of endogenous antioxidants in the Nrf2-Keap1 pathway and the prosurvival Akt pathway. Quercetin supplementation in vivo is also shown to significantly increase the number of surviving cells and new neurons in the dentate gyrus. To search for other potential active compounds in apple, I performed bioassay-guided fractionation whereby the flesh extract from apples of the Pinova cultivar was subjected to liquid- and solid phase separation and the active fraction was determined using primary neurosphere assays using cells derived from adult mouse dentate gyrus. Using mass spectometry, we revealed that the active compounds in the apple flesh extract are dihydroxybenzoate glycosides, which are non-flavonoid benzoic acid derivatives. I also confirmed that the isomers of these compounds; 2,3- and 3,5 dihydroxybenzoic acids significantly increase the number of neurospheres. Interestingly, 3,5 dihdroxybenzoic acid is an agonist of lactate receptor hydroxycarboxylic acid receptor 1 (HCAR1), with an even higher affinity than lactate. This receptor is suggested to mediate neurotrophic actions such as increasing production and release of BDNF. I also demonstrated for the first time that this receptor is presence in adult hippocampal precursor cells. To observe whether customary fruits or fruit-related products consumption affects adult hippocampal neurogenesis, I performed an experiment giving apple juice supplementation ad libitum to mice. I did not find a significant increase in net neurogenesis or the performance in the Morris water maze after apple juice supplementation. This is likely due to the low concentration of active compounds in apple juice failing to reach an effective concentration in the body. I conclude that apples provide potential proneurogenic compounds that can influence adult hippocampal neurogenesis through the activation of endogenous antioxidant mechanisms and molecular pathways for cell survival. Further studies are necessary to investigate the role of HCAR1 activation on adult hippocampal neurogenesis, which is a potential new mechanism to explain the health benefits of fruit and vegetable consumption. / Eine Ernährung die täglich reich an Obst und Gemüse ist, hat insbesondere bei älteren Menschen einen positiven Einfluss auf kognitive Fähigkeiten. Pflanzeninhaltsstoffe wirken als natürliche Antioxidantien, indem sie oxidative Stressoren neutralisieren. Weiterhin beeinflussen pflanzliche Nährstoffe molekulare Signalwege welche beim Überleben von Neuronen eine Rolle spielen. Die adulte hippocampale Neurogenese ist ein dynamischer, lebenslanger Prozess, bei dem aus Vorläuferzellen funktionelle neue Neuronen in der Körnerzellschicht des Gyrus dentatus gebildet werden. Dieser Prozess trägt zur Plastizität des Gehirns bei und spielt eine bedeutende Rolle beim Lernen und für das Gedächtnis. Externe Stimuli wie zum Beispiel eine reizreiche Umgebung und körperliche Aktivität wirken als positive Regulatoren und begünstigen die adulte hippocampale Neurogenese. Welche Rolle die Ernährung dabei spielt und ob Nahrungsbestandteile einen proneurogenen Effekt auf adulte hippocampale Vorläuferzellen haben ist kaum bekannt. In diesem Projekt habe ich den Effekt von Nahrungsbestandteilen aus Äpfeln, welche eine bedeutende Quelle von pflanzlichen Nährstoffen in unserer Ernährung darstellen, auf die adulte hippocampale Neurogenese untersucht. Ich habe gezeigt, dass Querzetin, das am reichlichsten in Äpfeln enthaltende Polyphenol, in der Monolayer-Zellkultur den Austritt aus dem Zellzyklus induziert und die Differenzierung von adulten hippocampalen Vorläuferzellen fördert. Des Weiteren steigert Querzetin nach der Differenzierung in vitro die Anzahl an überlebenden Zellen. Dies geschieht durch die Aktivierung von endogenen Antioxidantien des Nrf2-Keap1-Signalweges und des für das Überleben von Zellen förderlichen Akt-Signalweges. Die Verabreichung von Querzetin in vivo als Nahrungsergänzungsmittel führte ebenfalls zu einem signifikanten Anstieg der Anzahl an überlebenden Zellen und neu gebildeten Nervenzellen im Gyrus dentatus. Um weitere potentiell aktive Wirkstoffe von Äpfeln zu bestimmen, habe ich eine Bioassay-ausgerichtete Fraktionierung durchgeführt, wobei der Fruchtfleischextrakt von Äpfeln der Sorte Pinova einer Fest-/ Flüssig-Separation unterzogen wurde. Die aktive Fraktion wurde anhand der primären Neurosphäre-Assay-Methode mit Zellen aus dem Gyrus dentatus adulter Mäuse ermittelt. Mittels spektrometrischer Analyse habe ich gezeigt, dass die aktiven Wirkstoffe im Fruchtfleischextrakt von Äpfeln zur Gruppe der Dihydroxybenzol-Glykosiden gehören, welche den nicht-flavonoiden Benzoesäure-Derivaten zuzuordnen sind. Im in vitro Neurosphäre-Assay habe ich zudem gezeigt, dass die Isomere dieser Wirkstoffe, die 2,3- und die 3,5-Dihydroxybenzoesäuren, die Anzahl der Neurosphären signifikant erhöhen. Interessanterweise ist die 3,5-Dihydroxybenzoesäure ein Agonist des Laktatrezeptors Hydroxycarboxylic acid receptor 1 (HCAR1) und weist sogar eine noch höhere Affinität als Laktat auf. Es wird suggeriert, dass dieser Rezeptor neurotrophische Wirkungen vermittelt, wie zum Beispiel eine erhöhte Produktion von BDNF und dessen Ausschüttung. Zudem habe ich das Vorkommen dieses Reporters erstmalig bei adulten hippocampalen Vorläuferzellen nachgewiesen. Um zu untersuchen, ob der Konsum handelsüblicher Obstprodukte die adulte hippocampale Neurogenese beeinflusst, habe ich Mäusen Apfelsaft ad libitum verabreicht. Nach der Gabe von Apfelsaft sah ich keinen signifikanten Anstieg der Gesamtneurogenese und keine Verbesserung der Leistungsfähigkeit im Morris-Wasserlabyrinth-Test. Dies ist bedingt durch eine zu geringe Konzentration der aktiven Wirkstoffe im Apfelsaft wodurch die wirksame Konzentration im Körper nicht erreicht wird. Ich schlussfolgere, dass in Äpfeln potentielle pro-neurogene Inhaltsstoffe enthalten sind, welche die adulte hippocampale Neurogenese beeinflussen. Dies wird insbesondere durch die Aktivierung endogener antioxidativer Mechanismen und molekularer Signalwege vermittelt, die für das Überleben von Zellen von Bedeutung sind. Weitere Studien sind nötig, um zu bestimmen wie sich die Aktivierung von HCAR1 auf die adulte hippocampale Neurogenese auswirkt. Dies stellt einen potentiellen neuen Wirkmechanismus dar, welcher die gesundheitlichen Vorteile von Obst- und Gemüsekonsum belegt.

A realidade das organizações atualmente faz com que os desafios apresentados sejam enfrentados procurando-se a maior eficácia para suas soluções e com isso surjam as adaptações necessárias as constantes mudanças de maneira que os entraves sejam solucionados levando em consideração toda a amplitude que apresentarem. A Teoria da Complexidade por sua essência pode propiciar uma visão mais próxima da realidade, auxiliando na busca pelo entendimento de processos relacionados a gestão dos sistemas. Essa abordagem pode proporcionar uma maior efetividade nas ações das organizações, podendo servir de suporte para o melhor entendimento dos relacionamentos e das necessidades dos atores tanto internos como dos atores externos envolvidos nas organizações. Este trabalho foi construído a partir da necessidade do entendimento de como acontecem os relacionamentos entre os integrantes da cadeia produtiva da maçã para a partir disso propor mecanismos que possam auxiliar na melhoria das inter-relações. Assim, utilizou-se a abordagem do anel tetralógico para auxiliar na identificação das ações decorrentes da implementação da PIM na cadeia produtiva da maçã nos estados do Rio Grande do Sul e Santa Catarina. Trata-se de uma pesquisa qualitativa, operacionalizada através de um estudo de caso. Para que os objetivos fossem atingidos foi realizada uma revisão teórica a cerca dos pilares que sustentam o estudo, cadeia produtiva, relacionamento e teoria da Complexidade. Baseando-se na revisão teórica foram construídos os procedimentos metodológicos para a coleta e análise dos dados. A realização do estudo de caso realizou-se a partir de entrevistas com especialistas integrantes da cadeia produtiva da maçã brasileira. A análise dos dados proporcionou a evidencia de resultados como: identificação dos conceitos do anel tetralógico na implementação da Produção Integrada de Maçã; verificação das estratégias que a cadeia produtiva da maçã utiliza como norteadores do sistema; presença nos relacionamentos de ações e atitudes que trazem ao sistema a necessidade de trabalho voltado para o comportamento de cooperação e trabalho em equipe; além da necessidade de uma reorganização voltada para o cumprimento dos processos de certificação por parte do elo compradores atacadistas e varejistas, assim como a conscientização dos consumidores finais para a exigência de controle de qualidade no momento da compra. / The reality of the organizations at present does so that the presented challenges are faced looking for the biggest efficiency for his solutions and the necessary adaptations appear for the constant changes so that the hamper are solved taking into account the whole breadth what to present. The Theory of the Complexity for his essence can give a vision more near the reality, helping in the search for the understanding of processes related of the systems of management. This approach can provide a bigger effectiveness in the actions of the organizations, being able to serve of support for the best understanding of the relationships and of the necessities of the actors so the internal as the external actors wrapped in the organizations. This work was fulfilled from the necessity of the understanding of how the relationships happen between the integrants of the productive chain of the apple for from that to propose mechanisms that could help in the improvement of the inter-relations. So, there was suggested the use of the approach of the tetralogic ring for help in the identification of the actions resulting from the implementation of the PIM in the productive chain of the apple in the states of Rio Grande do Sul and Santa Catarina. So that the objectives being reached it was carried out a theoretical revision around the pillars that support the study, productive chain, relationship and theory of the Complexity. Being based on the theoretical revision there was built proceedings for the collection and analysis of the data. The realization of the study case happened from interviews with specialists, integrant of the productive chain of the Brazilian apple. The analysis of the data provided shows up of results like: identification of the concepts of the tetralógic ring in the implementation of the Integrated Production of Apple; checking of the strategies that the productive chain of the apple uses how direction of the system; presence in the relationships of actions and attitudes that bring to the system the necessity of work turned to the behavior of cooperation and work in team; besides the necessity of a reorganization turned to the fulfillment of the processes of certification for part of the link wholesale and retail buyers, as well as the conscience of the final consumers for the demand of quality control at the moment of the purchase.

O contexto da globalização é um processo evolutivo da sociedade, aliado a outros fatores que impõem às empresas a formação de diferentes arranjos, na busca de se manterem no mercado competitivo. As mudanças, nesse cenário mundial, dificultam as condições de sobrevivência das empresas, obrigando as mesmas a estabelecerem relações cooperativas, com vistas a obter os fatores de produção necessários à sua manutenção nos mercados. No que se refere à cadeia produtiva da maçã, objeto deste estudo, a área cultivada no mundo vem decrescendo desde 1996. Entretanto, na América do Sul, observa-se uma tendência crescente de incremento de área cultivada. A pesquisa teve como objetivo avaliar o desempenho competitivo da cadeia produtiva de maçã na Região Sul do Brasil, tendo como referência os maiores produtores dos Estados de Santa Catarina (SC), Rio Grande do Sul (RS) e Paraná (PR). O estudo utilizou como embasamento teórico a Teoria dos Sistemas, Cadeia Produtiva, Diagnóstico da Cadeia Produtiva, Desempenho da Cadeia Produtiva e, por fim, Indicadores de Desempenho de qualidade, eficiência, equidade, sustentabilidade e competitividade da cadeia. Para atingir os objetivos, a pesquisa foi do tipo qualitativa, com caráter exploratório e operacionalizado mediante um de estudo de caso. A coleta de dados foi realizada por meio de entrevistas em profundidade, semiestruturadas aos elos da cadeia produtiva da maçã, ou seja, os fornecedores de insumos, o produtor, o packing house e o distribuidor, bem como os especialistas, totalizando 26 agentes da CPM, escolhidos por conveniência. Mediante análise dos dados, ficou evidenciado que há vários fatores negativos e positivos que impactam a cadeia. Os pontos negativos foram: falta de organização, falta divulgação, mão de obra não qualificada e com custo alto, excesso de burocracia dos agentes financeiros, deficiência de capital, pulverização excessiva da oferta, não há relacionamento entre os elos da CPM. Entre outros, dos pontos positivos, destaca-se a utilização de tecnologia avançada no packing house, no porta-enxerto; a utilização da certificação como a Globalgap. Também detectou-se preocupação com a questão ambiental e social. / The context of globalization is an evolutionary process of society, together with other factors that require the companies to form different arrangements, seeking to remain competitive in the market. The changes in this global scenario, difficult conditions for the survival of companies, forcing them to establish cooperative relationships in order to obtain the factors of production necessary to maintain the markets. With regard to the productive chain of the apple, the object of this study, the cultivated area in the world has been falling since 1996. However, in South America, there is a growing tendency for increases in area cultivated. The research aimed to assess the competitive performance of the productive chain of the apple in the South of Brazil, with reference to the major producers of the States of Santa Catarina (SC), Rio Grande do Sul (RS) and Paraná (PR). The study used as the theoretical foundation of systems theory, productive chain, productive chain diagnostics, performance of the productive chain, performance Iidicators order to base the assessment of quality, efficiency, equity, sustainability and competitiveness of the chain. To achieve the objectives the methodology was a qualitative study, exploratory and operationalized through a case study. As a tool for data collection were conducted through interviews in depth semi-structured to the productive chain of the apple and the suppliers of inputs, producer, packing house and distributors, as well as specialists, totaling 26 agents CPM, chosen by convenience. By analyzing the data it was evident that there are several factors that impact both positive and negative chain. The negative points were lack of organization, poor disclosure, unskilled labor and high cost, excessive bureaucracy of financial agents, the deficiency of capital, spraying too much supply, there is no relationship between the links of the CPM. Among the positive highlights the use of advanced technology in the packing house, the rootstock, using certified as Globalgap. Also detected the concern about the environmental and social.

As crescentes exigências por qualidade e demanda a alimentos seguros pressionam as cadeias agroalimentares, para que adotem sistemas produtivos alternativos, e que estes gerem produtos saudáveis e inócuos ao consumo humano, por meio de práticas rastreáveis, visando à proteção do meio ambiente, dos trabalhadores e dos consumidores. A Produção Integrada de Maçã (PIM) surgiu como uma resposta a essas exigências, atuando como uma ferramenta de padronização da produção dessa fruta. A partir disso, o trabalho verificou se a adoção da PIM, na cadeia produtiva de maçã, é suficiente para que esse produto não esteja sujeito a barreiras técnicas e não tarifárias do mercado externo. Para isso, foram pesquisadas quais certificações para maçã são mais relevantes aos mercados consumidores, buscando identificar e classificar os requisitos e qual o posicionamento da PIM perante essas regulamentações. Para tanto, foi desenvolvido um estudo exploratório, por meio de pesquisa bibliográfica, documental e de levantamento dentro da PIM, pelo qual foi possível identificar que necessidade de ajustes para que esse programa mantenha sua relevância como certificação na cadeia produtiva da maçã, pois não possui a equiparação aos selos internacionais, necessária para sua aceitação no Exterior e nem conhecimento no mercado nacional. / The increasing demand for quality and safe food is been pushing the agri-food chains to adopt alternative production systems, with the purpose of generate healthy and innocuous products for human consumption through traceable practices, in order to protect the environment, workers and consumer. The integrated apple production (PIM) has emerged as a response to these requirements, serving as a tool to standardize the production of this fruit. From this, the study examined whether the adoption of pim in apple production chain, it is enough to avoid that this product being a subject for technical and non-tariff barriers in the foreign market. Considering this, it was researched which apple certifications are more relevant to the consumer markets, looking for identifying and classifying the requirements and also which is the positioning of the pim considering this kind of regulations. Therefore, was developted an exploratory study, through a bibliografic, documental and survey research inside the PIM, from which it was possible identify that the PIM requires adjustments to maintain its relevance as a certification in the apple productive chain, because it still does not have the equalization to the international labels, that is required to its acceptance on abroad, or even the recognition in the domestic market