Dans le Supergroupe Ouest-Congolais du bassin du Niari-Nyanga (Afrique centrale), les marqueurs des Glaciations Globales Sturtienne et Marinoenne sont représentés par les formations des «Diamictite inférieure» et «Diamictite supérieure».Ce travail de thèse présente une étude à haute résolution du Cap Carbonate associé à la Diamictite supérieure (6 coupes dans le bassin et 2 coupes dans la zone externe de la Chaîne du Mayombe). Les études pétrographiques révèlent la préservation des structures sédimentaires primaires et permettent de définir six microfaciès (MF0 à MF5) caractéristiques des paléoenvironnements de types inter- à supratidaux ou subtidaux. Dans le Cap Carbonate étudié, les indices de Kübler montrent une évolution croissante depuis la diagenèse profonde dans le bassin jusqu'à l'épimétamorphisme dans la zone externe de la Chaîne du Mayombe. Le signal isotopique ([delta]13C et [delta]18O) des Cap Carbonate échantillonnés est généralement reproductible dans le synclinal comme dans la chaîne, avec les valeurs du [delta]13C montrant une excursion négative variant de -2.6 [pour mille] à -5.6 [pour mille]. Les valeurs de d18O oscillent entre -6 [pour mille] et -12 [pour mille]. Par ailleurs, la confrontation des données minéralogiques, chimiques et isotopiques indique une influence négligeable des transformations post-sédimentaires sur la signature isotopique du Cap Carbonate indiquant la préservation des valeurs du [delta]13C de l'océan néoprotérozoïque. Enfin, l'ensemble des données de cette thèse et les résultats préliminaires des « Projets GLANEC» replacés dans un contexte régional permettent de définir le Membre SCIa du synclinal du Niari-Nyanga comme un Cap Carbonate lié à la Glaciation Marinoenne. / Within West-Congolian Supergroup of Niari-Nyanga Basin (Central Africa), the markers of Sturtian and Marinoan Global Glaciations are documented by the so-called «Lower Diamictite» and «Upper Diamictite». This work is based on 6 and 2 lithological sections from the basin and the external zone of the Mayombe fold belt. It corresponds to a high-resolution study of the Cap Carbonate lying unconformably on the Upper Diamictite. Petrographic analyses show preservation of primary sedimentary structures and lead to define six microfacies (MF0 to MF5). These microfacies caracterize paleoenvironments such as inter- to supratidal or subtidal types. Kübler index values of the studied Cap Carbonate display an increasing evolution from East to West, ie from a deep diagenesis in the basin to an epimetamorphism in the Mayombe external zone. Stable isotope signature ([delta]13C, [delta]18O) of the various components of this Cap Carbonate is reproducible throughout the basin as in the Mayombe external zone, with [delta]13C values displaying a negative excursion, decreasing from -2.6 ? to -5.6 ?. [delta]18O values of these components vary between -6 ? and -12 ?. Moreover, comparison between mineralogic, chemical and isotopic data indicates that post-sedimentary transformations had a very negligible influence on the isotopic signature of the Cap Carbonate, indicating preservation of d13C values of the Neoproterozoic ocean. Finally, when they are compared with other regional studies, all data of the present work and the preliminary results of the GLANEC Projects lead to the conclusion that the SCIa Member of the Niari-Nyanga Basin must be considered as a Cap Carbonate related to the Marinoan Global Glaciation.

Das Dorsalgefäß von Drosophila ist ein wertvolles Modellsystem für die Untersuchung der genetischen und molekularen Mechanismen der Kardiogenese. Ein Schlüsselereignis der Kardiogenese ist die Bildung eines Herzlumens, durch das die Hämolymphe gepumpt wird, um Nährstoffe und Zellen des angeborenen Immunsystems zu zirkulieren. Ein Schwerpunkt meiner Arbeit umfasste die Identifizierung neuer Gene, die im embryonalen Dorsalgefäß von Drosophila exprimiert sind. Dafür habe ich die Expression von 101 Genen, deren Orthologe spezifisch im Herzen von Zebrafisch exprimiert sind, in Drosophila untersucht. Ich identifizierte ein Gen, das für das Cbl-assoziierte Protein (CAP) kodiert. Durch Herstellung eines anti-CAP Antikörpers konnte ich erstmals eine detaillierte Lokalisation des CAP-Proteins im Dorsalgefäß beschreiben. Interessanterweise stellte sich dabei heraus, dass CAP ähnlich wie die homologen Vertebraten Proteine embryonal an den fokalen Adhäsionskontakten der Kardioblasten und im adulten Dorsalgefäß auch an den Z-Scheiben und den Zell-Zell-Kontaktstellen der Kardiomyozyten lokalisiert ist. Des Weiteren untersuchte ich, welche Auswirkungen der Verlust der CAP Funktion auf die Herzentwicklung hat. Für die Analyse der CAP-Mutanten nutzte ich neben Immunhistochemischen Methoden auch ultrastrukturelle Analysen mittels TEM-Mikroskopie. So konnte ich zeigen, dass embryonale Dorsalgefäße von CAP-Mutanten eine fehlerhafte Anzahl sowie Anordnung der Kardioblasten und Lumendefekte aufweisen. Ein genetischer Interaktionstest untermauerte meine Vermutung, dass CAP mit dem Integrinsignalweg während der embryonalen Dorsalgefäßentwicklung interagiert. Live-Aufnahmen des pumpenden Dorsalgefäßes von Drosophila L3-Larven und Injektionstests an späten Puppen zeigten zudem, dass der Verlust der CAP Funktion auch zu starken Defekten in der Funktionalität des larvalen und adulten Dorsalgefäßes führt. / The heart of Drosophila provides a valuable model system for the examination of the genetic and molecular mechanisms that guide cardiogenesis. A key event of cardiogenesis is the formation of a heart lumen through which the hemolymph is pumped to circulate nutrients and cells of the innate immune system. A main focus of my work was the identification of new genes that are expressed in the embryonic heart of Drosophila. Therefore I studied the expression of 101 genes, whose orthologues are expressed specifically in the heart of zebrafish. I identified a gene that encodes for the Cbl-associated protein (CAP). By generating an anti-CAP antibody I could describe the localization of the CAP protein in the heart for the first time in detail. Interestingly, it turned out that CAP is located similar to the homologous vertebrate proteins at the focal adhesion contacts of cardioblasts in the embryo and at the Z-discs and the cell-cell contact sites of cardiomyocytes in the adult heart. I also examined the consequences of the loss of CAP function on heart development. For the analysis of the CAP mutants I used immunohistochemical and ultrastructural analysis by TEM microscopy. So I was able to demonstrate that embryonic hearts of CAP mutants show a defective number and arrangement of cardioblasts and lumen defects. A genetic interaction test substantiated my guess that CAP interacts with the Integrin signaling pathway during embryonic heart development. Live recordings of the pumping heart of Drosophila L3 larvae and injection tests of late pupae also showed that the loss of CAP function leads to severe defects in the functionality of the larval and adult heart.

Bakgrund: Redovisnings- och företagsskandaler som ägde rum på 2000-talet i USA och flera europeiska länder satte fart på bolagsstyrningsdebatten. Många länder började införa regler med syfte att förbättra bolagsstyrningen och öka förtroendet för näringslivet. Sverige drabbades liksom andra länder av redovisningsskandaler, och som följd till detta infördes den svenska koden för bolagsstyrning för att återuppbygga marknadens förtroende för de svenska bolagen. Första juli 2005 tillämpades koden i Stockholmsbörsen för alla bolag på A-listan och O-listan med börsvärde över 3 miljarder kronor det vill säga de bolag som ingick i kategorin Large Cap.Syfte: Syftet med denna uppsats är att undersöka och analysera hur bolag på OMX Stockholmsbörsen, Large Cap, avviker från koden och om de avviker från samma punkter i koden samt hur utförligt förklarar dessa bolag avvikelserna. Med hjälp av vetenskapliga artiklar som teoretiskt perspektiv vill jag få förståelse för varför koden finns och varför bolag avviker från den samt undersöka om koden fungerar som det var tänkt.Metod: För att undersöka i vilken omfattning bolag avviker från koden och vilka punkter det som bolagen avviker från har jag läst igenom och granskat bolagens årsredovisningar och bolagsstyrningsrapporter.Teoretisk referensram: I detta kapitel har jag tagit upp tidigare forskning som handlar om andra länders bolagskoder och principen följa eller förklara, samt orsaker till varför bolag väljer att följa eller avvika från koden. Dessa studier är gjorda i Tyskland och Storbritannien.5Empiri: Det empiriska materialet består av årsredovisningar och bolagsstyrningsrapporter för de undersökta 28 bolagen inom kategorin Large Cap. Jag har undersökt de senaste åren när jag gjorde undersökningen, dvs. 2010 och 2011.Slutsatser: Det jag kom fram till i min studie är att ägarstrukturen är en bidragande faktor till varför bolag väljer att avvika från koden. Bolag med ett koncentrerat ägande tenderar att avvika från koden. Dessutom har jag märkt att dessa bolag ägs av Industrivärden, Investor. De bolagen kännetecknas även av att de har starka familjeägare som äger mer än 30 % av aktierna, dessa ägare vill oftast ha kontroll över bolaget och därför avviker de från den svenska koden. / Background: Accounting and corporate scandals that took place in the 2000s in the United States and several European countries took off in the corporate governance debate. Many countries began to adopt rules designed to develop corporate governance and increase confidence in the business world. Sweden suffered like other countries of accounting scandals, and as a result of this came the Swedish Code of Corporate Governance to rebuild market confidence to the Swedish companies. The first of July 2005 the code was applied in the Stockholm Stock Exchange for all companies on the A-list and the O-list with market capitalization exceeding 3 billion i.e. companies included in the Large Cap. Purpose: The purpose of this study is to examine and analyze how companies on the OMX Stockholm Stock Exchange, Large Cap, deviates from the Swedish code and if they deviate from the same points in the code and how thoroughly these companies explains their deviations. I want to get an understanding of why the code exists and why the companies deviate from it and whether the code works as expected. Methodology: To examine the extent to which companies deviate from the code and which points that the companies differ from, I have studied and observed the companies' annual reports and corporate governance reports. Theoretical Framework: In this chapter, I have raised earlier research that deals with other codes and the principle comply or explain, and the reasons why companies choose to follow or deviate from the code. These studies took place in Germany and the UK.7Empirical foundation: The empirical data consists of annual reports and corporate governance reports of the surveyed 28 companies in the Large Cap from both 2010 and 2011. Conclusions: The conclusion of this study is that the ownership structure is a contributing factor to why companies choose to deviate from the code. Companies with a concentrated ownership tend to deviate from the code. I have also noticed that these companies are owned by Industrivärden and Investor. The companies are also characterized by having strong family owners who own more than 30% of the shares, the owners usually want to have control over the company and that are why they differ from the Swedish Code.

Made available in DSpace on 2010-04-20T21:00:05Z (GMT). No. of bitstreams: 4 Alex Futoshi Tanaka.pdf.jpg: 14145 bytes, checksum: 37f8902a745fb7b661585650891b6319 (MD5) Alex Futoshi Tanaka.pdf.txt: 118382 bytes, checksum: fe5ed7aa85965a165f2df875ae29311f (MD5) license.txt: 4886 bytes, checksum: d32d1a33c83956bd8f0eb87d283d398a (MD5) Alex Futoshi Tanaka.pdf: 385478 bytes, checksum: 8203b76ba07c71da04dd04b6bc617a35 (MD5) Previous issue date: 2009-02-04T00:00:00Z / Esse estudo tem como objetivo construir diversas carteiras com estratégias de investimento (investment styles) em ações baseadas em diferentes critérios quantitativos com o intuito de descobrir quais estratégias prevalecem sobre as outras em termos de retorno e risco da carteira no período de 1996 a 2007 no mercado brasileiro. A construção das carteiras é realizada para todas as empresas listadas na Bovespa no período citado. Há evidências de que a estratégia de valor preço/lucro (value PE) apresentou a melhor consistência nos resultados estatísticos, análise do índice Sharpe e na análise de rendimento entre as carteiras estudadas.

År 2007-2008 inträffade finanskrisen vilket skapade oro på den finansiella marknaden. Oron återspeglades i antalet svenska aktieägare som minskade successivt fram till år 2014. Därefter fram till idag visar statistiken att svenska aktieägare blir fler för varje år som går. En förklaring är för att digitaliseringen har skapat enklare lösningar för privatpersoner att börja spara i aktier vilket ökar tillgängligheten och inflödet. Ett ökat intresse och en ökad tillgänglighet behöver dock inte innebära en ökad kunskap hos investerarna, vilket talar för att det är relevant att dels förmedla kunskap kring aktier men framförallt identifiera den bästa investeringsstrategin som kan vägleda investerare. Syftet med uppsatsen är att undersöka om värde- eller tillväxtinvestering ger högst avkastning på Stockholmsbörsen och Micro-cap under 2012-2016. Studien tillämpar en deduktiv ansats tillsammans med en kvantitativ forskningsmetod. För att kunna ta reda på den bästa investeringsstrategin på Stockholmsbörsen och Micro-cap har sekundärdata i form av nyckeltal samt kurshistorik samlats in, bearbetats och analyserats. Med hjälp av nyckeltalen P/E och P/B har aktier kunnat kategoriseras som värde- respektive tillväxtaktier. Vidare kunde portföljer skapas av respektive kategori för att sedan vara jämförbara med varandra. Resultatet visar på att investeringsstrategin värdeinvestering tenderar att prestera bäst. Värdeinvestering presterade bäst oavsett om portföljerna bestod av aktier enbart från Stockholmsbörsen eller både Stockholmsbörsen och Micro-cap. Resultatet som erhölls visade att tillväxtinvestering presterar betydligt högre avkastning än värdeinvestering oavsett börs/handelsplattform dock utsätts en investerares kapital för så pass hög risk med tillväxtinvestering att när studien riskjusterar avkastningen är det värdeinvestering som presterar bäst. / The financial crisis during 2007-2008 concerned investors internationally. The Swedish investors’ concern was reflected in the number of shareholders which decreased until 2014. From 2014 and until today the statistics shows that Swedish shareholders are increasing. One explanation could be the digitization that created solutions for investors to buy stocks more easily. But an increased availability does not necessarily mean that the knowledge also has increased. This is one of the reasons for the importance of spreading knowledge to investors and identify the best investment strategy for guidance. The purpose is to investigate the investment strategies value investing and growth investing. To find out the best investment strategy the thesis has used the two ratios P/E and P/B and historical share prices. The stocks that are included in this thesis is both from Stockholm Stock Exchange but also from Micro-cap. The thesis has used a quantitative research method when gathering all the necessary information and a deductive approach in relation to the theories. By using the presented ratios, the thesis could categories the stocks in the respective strategy. The superior investment strategy is value investing which tends to perform the best risk-adjusted return during the time 2012-2016. Value investing tends to perform the best return regardless if the portfolio contains only stocks from Stockholm Stock Exchange or both Stockholm Stock Exchange and Micro-cap. The result showed that growth investing had the most extreme returns and would have won if the result did not adjust for the risk taken.

Titel: Hållbarhetsinformation i VD-ordet- En kvantitativ studie av företag på OMX Stockholm Large CapFörfattare: Magnus Olsson och Karl AmbrosiussonBakgrund: VD-ordet är ett frivilligt avsnitt i årsredovisningen där företagsledningen och den verkställande direktören har möjlighet att uttrycka sig om det gångna året och framtiden. VD-ordet är en av de mest lästa delarna i årsredovisningen. Denna uppsats fokuserar på i vilken utsträckning hållbarhetsinformation framhävs i VD-ordet. Hållbarhetsredovisning är sedan 2016 ett krav för större företag och 2017 års årsredovisningar är de första som måste innehålla en hållbarhetsrapport.Syfte: Syftet med uppsatsen är att utforska om lagändringen med krav på hållbarhetsrapportering har påverkat i vilken utsträckning hållbarhetsinformation presenteras i VD-ordet. Syftet är vidare att förklara om företagets storlek är en faktor som påverkar mängden hållbarhetsinformation som presenteras i VD-ordet.Metod: Kvantitativ innehållsanalys har tillämpats för att mäta i vilken utsträckning hållbarhetsinformation används i VD-ordet genom att räkna hur ofta begrepp som förknippas med hållbarhet förekommer.Slutsats: Mängden hållbarhetsinformation i VD-ordet har ökat mellan 2016 och 2017, men lagändringen har inte medfört någon extra påverkan. Resultatet visar också att ett företags storlek inte påverkar mängden hållbarhetsinformation i VD-ordet hos de undersökta företagen. / Title: Sustainability information in the CEO letter- A quantitative study of companies at OMX Stockholm Large CapAuthors: Magnus Olsson and Karl AmbrosiussonBackground: The CEO letter is a voluntary section in the annual report where the management together with the CEO have the opportunity to express themselves about the past year and future expectations. The CEO letter is one of the most read parts in the annual report. This essay focuses on to what extent the CEO letter presents sustainability information. A Sustainability report has been a requirement for bigger companies since 2016 and the annual reports of 2017 are the first reports that have to contain a sustainability report.Purpose: The purpose of this essay is to find out if the new sustainability reporting requirements has affected the extent of sustainability information presented in the CEO letter. The purpose is further to explain whether the size of the company is a factor that affects the amount of sustainability information presented in the CEO letter.Method: Quantitative content analysis has been applied to measure the extent to which sustainability information is used in the CEO letter. It’s used by counting the frequency of concepts associated with sustainability.Conclusion: The result shows that the amount of sustainability information in the CEO letter has increased between 2016 and 2017, but that the change in the law did not have any additional impact on the amount of sustainability information. The result also shows that size of the companies doesn’t affect the amount of sustainability information in the CEO letter for the investigated companies.

Dans cette thèse, nous décrivons explicitement la structure multiplicative et la structure d’algèbre de Lie graduée sur la cohomologie de l’algèbre enveloppante d’une algèbre de Lie de dimension finie. Dans un premier temps, nous introduisons une structure multiplicative de la cohomologie de l’algèbre de Lie. Ensuite, nous montrons explicitement qu’il existe un isomorphisme d’algèbres graduées commutatives entre l’algèbre de cohomologie de Hochschild de l’algèbre enveloppante munie du produit cup et l’algèbre de cohomologie de l’algèbre de Lie. Dans un deuxième temps, nous introduisons une structure d’algèbre de Lie graduée sur la cohomologie de l’algèbre de Lie. Ensuite, nous montrons qu’il existe un isomorphisme d’algèbres de Lie graduées entre l’algèbre de Lie de cohomologie de Hochschild de l’algèbre enveloppante munie du crochet de Gerstenhaber et l’algèbre de cohomologie de l’algèbre de Lie. Enfin, nous décrivons complètement le crochet de Gerstenhaber sur la cohomologie de Hochschild de l’algèbre enveloppante d’une algèbre de Lie de dimension _ 3. / In this thesis, we explicitly describe the multiplicative structure and the graded Lie algebra structure of the cohomology of finite-dimensional Lie algebras. In a first step, we introduce a multiplicative structure for the cohomology of Lie algebra. Then, we explicitly show that there exists an isomorphism of commutative graded algebras between the Hochschild cohomology algebra of the enveloping algebra provided with the cup product and the cohomology algebra of the Lie algebra. In a second step, we introduce a graded Lie algebra structure for the cohomology of Lie algebra. Then, we show that there exists an isomorphism of graded Lie algebras between the Hochschild cohomology Lie algebra of the enveloping algebra provided with the Gerstenhaber bracket and the cohomology algebra of the Lie algebra. Finally, we describe completely the Gerstenhaber bracket on the Hochschild cohomology of the enveloping algebra of a Lie algebra for dimension _ 3.

Thesis discusses distributed database systems and its advantages and disadvantages. Further, text informs about document database CouchDB, storage of documents, synchronization and CAP theorem. The aim of the thesis is to implement distributed document management system and workflow management system based on CouchDB. The system contains a cluster with three CouchDB nodes with HAProxy in front, which does load balancing. The system allows creation of any document based on the template, manages its life cycle and workflow. It is also possible to create a custom workflow using BRMS rules. The implemented solution simplifies document management and workflow and allows a high degree of customization for the organizations needs.

Gli scenari agricoli europei rivelano un crescente interesse per le filiere corte come strumento di promozione dei sistemi alimentari locali. Nonostante i piccoli agricoltori siano la spina dorsale dell'agricoltura europea, gli interventi politici e legislativi che si sono susseguiti nei decenni non hanno sufficientemente tutelato ne promosso la loro attuale posizione in ambito socio-economico. Il presente lavoro mira a fornire un'approfondita analisi del ruolo delle filiere corte all'interno del quadro normativo europeo per comprendere se l’attuale legislazione sostiene o piuttosto inibisce questi sistemi alternativi di produzione e distribuzione alimentare. Muovendo dall'esame della pletora di definizioni attribuite alla filiera corta e soffermandosi su una revisione critica delle più significative riforme della PAC, in particolare alla luce della strategia 'Farm to Fork', vengono identificate nuove priorità che appaiono più favorevoli ai piccoli agricoltori. Lo studio è arrichito da un confronto tra l'approccio adottoato dell'UE - caratterizzato principalmente da strumenti di hard law e misure top-down -, e quello della California ‘socialmente auto-regolato’, in cui gli 'Alternative Food Movements' e le strategie bottom-up sono attori principali nella regolamentazione della filiere corte e del loro impatto sulla comunità. Lo scopo finale é quello di identificare potenziali elementi utili che, se adottati, potrebbero migliorare il modello europeo. / European agricultural landscapes are undergoing fundamental changes, revealing an increasing interest in Short Food Supply Chains as a tool to promote local food systems and products. Despite small farmers are the backbone of agriculture in the EU, both policy leadership and legal interventions have been not sufficiently fostering their position in the socio and economic today’s narrative. The study aims at providing an extensive analysis of the role of SFSCs within the EU legal framework to understand whether EU legislation supports or rather inhibits these alternative systems of production and supply. Moving from the examination of the plethora of SFSC definitions to a critical revision of the most significant CAP reforms, especially in the light of the ‘Farm to Fork’ strategy, new priorities that seem more favorable to small farmers are identified. The study is enriched by a comparison between the EU legal approach - mainly characterized by hard law instruments and top-down measures -, and the Californian ‘socially self-regulated’ approach, where Alternative Food Movements and bottom-up strategies act as the main player in regulating SFSCs and their impact on the community with the aim of identifying potential insights that could improve the EU model.

Mammalian oocyte is a highly differentiated cell which gives rise to an embryo after fertilization. Importantly, fully-grown oocytes become transcriptionally inactive at the end of the growth phase. During following stages of development, i. e. meiotic maturation of the oocyte and early embryonic development, only transcripts previously synthesized and stored are used. The tight correlation between mRNA distribution and subsequent protein localization and function provides a mechanism of spatial and temporal regulation of gene expression used by various cell types. However, not much is known about mRNA localization and translation in the mammalian oocyte and early embryo. The aim of my thesis was to determine the localization of transcripts and components of translational machinery in the mammalian oocyte and embryo and to uncover the mechanisms of spatiotemporal regulation of translation as a prerequisite for correct oocyte and embryo development. We have shown that nuclei of both mouse and human oocytes contain RNA molecules and RNA binding proteins. Following the nuclear envelope breakdown (NEBD), translational hot-spots occur in the area surrounding the nuclear region. We suppose that mRNAs previously retained in the nucleus are released to the cytoplasm during NEBD and their subsequent...