In longitudinal studies, the exact timing of an event often cannot be observed, and is usually detected at a subsequent visit, which is called interval censoring. Spacing of the visits is important when designing study with interval censored data. In a typical longitudinal study, the spacing of visits is usually the same across all subjects (balanced design). In this dissertation, I propose an unbalanced design: subjects at baseline are divided into a high risk group and a low risk group based on a risk factor, and the subjects in the high risk group are followed more frequently than those in the low risk group. Using a simple setting of a single binary exposure of interest (covariate) and exponentially distributed survival times, I derive the explicit formula for the asymptotic sampling variance of the estimate for the covariate effect. It shows that the asymptotic sampling variance can be simply reduced by increasing the number of examinations in the high risk group. The relative reduction tends to be greater when the baseline hazard rate in the high risk group is much higher than that in the low risk group and tends to be larger when the frequency of assessments in the low risk group is relatively sparse. Numeric simulations are also used to verify the asymptotic results in small samples and evaluate the efficiency of the unbalanced design in more complicated settings. Beyond comparing the asymptotic sampling variances, I further evaluate the power and empirical Type I error from unbalanced design and compare against the traditional balanced design. Data from a randomized clinical trial for type 1 diabetes are further used to test the performance of the proposed unbalanced design, and the parametric analyses of these data confirmed the findings from the theoretical and numerical studies.

L’essor de l’internet des objets engendre le développement et l’introduction de nouveaux capteurs dans l’industrie mais aussi dans les objets du quotidien. Bâtiments et usines mais aussi réfrigérateurs et lunettes regorgeront bientôt de capteurs sans fils connectés. L’utilisation de capteurs sans fils implique le développement d’antennes compactes à la conception complexe. Diverses technologies de capteurs sans fils et passifs (sans batterie) ont été étudiées ou sont d’ores et déjà disponibles dans le commerce. L’utilisation d’antennes miniatures dans ces technologies de capteur a été traitée dans la thèse. Plus intégrables, les antennes miniatures imposent des contraintes en termes d’efficacité et de facteur de qualité qui peuvent détériorer les performances du capteur. La conception, la modélisation ainsi que l’optimisation d’une antenne miniature particulièrement intéressante pour les capteurs sans fils et passifs sont présentées. Les résultats obtenus montrent l’intérêt de la méthode décrite pour améliorer les performances de telscapteurs / The Internet of Things is a promising research area for the next years. 50 billions of connected objects are expected in 2020. Among them, wireless sensors are required for appli- cations like body and environmental monitoring. This implies a lot of research works such as size reduction, efficiency im- provement and energy harvesting. The variety of applications and environments leads to a huge panel of constraints. In this context, chipless and passive sensors present numerous advantages such as long lifetime, low cost and robustness. This thesis has two aims : show the interest of using electrically small antenna in wireless sensors and developpe a method to improve sensors performance (range and sensibilitty)

This PhD submission constitutes a novel and accompanying critical commentary. My novel Nobody Killed Her provides an alternative history of the assassination of Pakistan's only female Prime Minister, Benazir Bhutto. The thesis questions the choices I made in order to develop the writing of this novel and the decisions I took in order for it to reach its readers. I discuss the issues of creative integrity and the role of the publisher as an enabler, and as a modern day censor. I examine the role of literary influences and publishing pressures on the multi-layered and shifting strains of the creative process and explore fiction as a powerful tool for communicating the paradoxical state of modern Pakistani women, which my novel draws upon. Accordingly, my research narrative is interspersed with personal vignettes that helped shape my writing. Reflecting upon the role of memory, history and politics, and literary influences that shape our writing, I try to interrogate the ‘flash-bulb’ moments of inspiration and argue that creative writing is actually a series of complex thought processes that shape our consciousness. I have also, during the compilation of this essay, looked critically at the role of the publisher in shaping an author’s creativity and the author’s desire for publication in influencing his or her creative choices. I have examined the role of the audience, by asking who the writer is writing for, concluding that the creative journey is more important than the destination i.e., the culmination of the writing into a published form. I conclude by contending that creative writing is above all communication, not just with the reader but also with one’s self. It is about self- expression and therefore must remain true to the self.

Orientador: Paulo Sergio de Vasconcellos / Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Estudos da Linguagem / Made available in DSpace on 2018-08-05T20:08:04Z (GMT). No. of bitstreams: 1 Trevizam_Matheus_D.pdf: 1578970 bytes, checksum: 5efb6b093537be187dbbbb5fa29ba95e (MD5) Previous issue date: 2006 / Resumo: Neste trabalho, propomos a análise conjunta de três obras da literatura agrária latina (o De agri cultura de Catão Censor, o De re rustica de Varrão e as Geórgicas de Virgílio) do ponto de vista da construção do texto (elaboração genérico-literária e da linguagem), dos significados particulares das posturas de "ensinamento" e dos temas-outros (moral, religião, filosofia, política, mito...) sempre agregados à trama instrutiva. Além disso, propõem-se traduções divulgadoras do De agri cultura catoniano e do primeiro livro do De re rustica / Abstract: In this work, we propose the common analysis of three books of Latin agrarian literature (the De agri cultura of Cato, the De re rustica of Varro and Virgil's Georgics) from the viewpoint of textual construction (generic, literary and linguistic elaboration), of the particular meanings in teaching ways followed by each writer and of the additional themes (moral, religion, philosophy, politics, myth...) always included in the instructional whole. We also propose popularization translations of the De agri cultura and of the first book of the De re rustica / Doutorado / Doutor em Linguística

abstract: In this dissertation, I translate and provide a critical analysis of the Iranian play, Tomb Dwellers (2009), by Hussein Kiyani. It was first staged after the contested presidential election in Iran in 2009 which brought Mahmoud Ahmadinejad into power for a second term. The play depicts the socioeconomic situation of Iran and its relation to other countries, the situation of women and the working class during Ahmadinejad’s two terms of presidency. Tomb Dwellers is written as a comedy, a genre more likely to make it past censors in Iran or other despotic countries. My research and translation project are sparked by questions that move in two directions simultaneously: one, toward understanding the sociopolitical context for theatre in Iran after the revolution of 1979; the other, toward the challenges of translating into English a play that stands as a social metaphor in its own historical context. Regarding the former, which forms the basis of my critical analysis, I explore the strategies artists have used to avoid the limitations imposed by the authorities. In making this play available to English-speaking readers at a time of political tension between Iran and the United States I offer to USAmerican audiences a more nuanced perspective of the way Iranian people feel about their government and its relation to other countries. This play is both timely and informative. Timely because of the tensions between the US and the Middle East. Informative because it represents the Iranian community and may serve to create a bridge between the two cultures. Translating and staging this play along with the critical analysis I am providing will help American audiences and immigrants from other countries to know more about Iran in a creative and entertaining way. / Dissertation/Thesis / Doctoral Dissertation Theatre 2019

(in English): Julio Cortázar is considered as one of the greatest literary figures of Argentina and Latin America of the last century and to him is dedicated this master's thesis, focused on translation of his work into Czech language. First part of the thesis is theoretically based, dealing with biography, creation and style of the author and then moves to figures of his Czech translators, problems arising from translation and perception and development of translations of Cortázar's works in Czech environment. The second part is practically oriented, pursuing the analysis and comparison of translations of specific works - two translations of a story The Pursuer by translators Kamil Uhlíř and Jan Machej and two versions of translation of a novel Hopscotch by Vladimír Medek.

A la déclaration de guerre en septembre 1939, la censure est rétablie sous le contrôle des militaires pour empêcher les critiques de la politique du gouvernement et encadrer les informations militaires. Les bureaux de la censure s'installent à Pau et contrôlent la presse départementale. Après l'armistice, la censure passe aux mains des civils et se structure dans le cadre d'une organisation régionale, dépendant d'une censure centrale à Vichy. En novembre 1941, la nomination à Pau d'Henri Peyre durcit le contrôle de presse. Les conflits se multiplient avec les trois quotidiens : Le Patriote, l'Indépendant et France Pyrénées. Le censeur transforme ses services en une officine de propagande et de délation. Il surveille de très près la vie publique et culturelle avec beaucoup de zèle. A la Libération, les journaux palois passent en jugement et disparaissent, le censeur est condamné à dix ans de travaux forcés. / Following the declaration of war in September 1939, censorship is reestablished under the control of military forces to prevent people from criticizing the government’s policy and to regulate the communication of military information. Censorship offices settle down in Pau and check the departmental press. After the armistice is signed, censorship falls into the hands of civilians and forms itself under a regional organization which depends on the central censorship office in Vichy. In November 1941, when Henri Peyre is nominated in Pau, measures to monitor the press are strengthened. There are increasing numbers of conflicts involving the three daily newspapers: Le Patriote, l'Indépendant and France Pyrénées. The censor transforms his services into a propaganda and informing outlet. He closely monitors the public and cultural life with great zeal. After the liberation, newspapers in Pau stand trial and disappear. The censor, in turn, is sentenced to ten years of forced labour.

Les patients atteints de cancer traversent des conditions d’existence extrêmes demandant un cadre spécifique de prise en charge psychothérapique. Le cancer et les soins anticancéreux indispensables, forment pourtant la situation cancéreuse envahie par les logiques processuelles du cancer, violentes. Cette situation peut être un raz de marrée dans la vie d’un sujet, emportant les convictions les plus établies et les bases narcissiques-identitaires et du caractère les plus ancrées. Le sujet présente un risque majeur d’effondrement. De plus, la puissance du traumatisme actuel puise ses racines dans la reviviscence de traumatismes primaires restés jusque là éteints. Leur retour a lieu sous la forme de sensations hallucinatoires induisant des états de corps et des états de perception du monde extérieur psychiquement irreprésentables. Le sujet se vit et s’éprouve alors passivement, sans pouvoir s’affecter véritablement. Mortifères, la pesanteur, l’inertie et la douleur dominent ou au contraire, le sujet se sent à vif, hypersensible, envahi, persécuté, au risque de l’éclatement. Le monde s’articule alors essentiellement sur cette bipolarité que vient recouvrir la défense opératoire radicale de la blancheur. Elle jette son dévolu sur le monde, les relations, les objets, les affects, le corps du sujet. Parfois, rien ne touche ce dernier dont la psyché s’est resserrée autour de son noyau archaïque aux limites psyché-soma. Le cancer éradique la subjectivité, subtilisant le principe actif des logiques de l’originaire. Cet état de mélancolie blanche parfois durable, n’est que l’une des phases d’une processualité mélancolique polymorphe. Cette dynamique domine la vie du sujet selon deux tendances à la proto-mélancolie et à la proto-manie, qui remplacent le monde affectif par une propension à l’inertie ou à la psychomotricité. Le travail de mélancolie vise la relance des capacités d’identification en impasse. Nous allons étudier les modalités spécifiques du transfert et en particulier la mobilisation essentielle d’un transfert formel de base. Il fonctionne à partir de l’activation originaire en double de signifiants formels alors partagés par le thérapeute et son patient. Des mouvements de léthargie et d’excitations psychocorporelles peuvent gagner le clinicien et plonger la relation thérapeutique dans des états crépusculaires, relatifs au cancer et au retour des traumatiques primaires. Nous verrons comment le but premier de la psychothérapie vise l’utilisation psychique – et non l’éradication – de l’objet-cancer, comme moyen de forger les conditions de viabilité du cadre : permettre la mise en représentation des états de corps, rétablir la symbolisation, l’imagination et le recours aux fantasmes inconscients. Ce sont là les bases indispensables d’une psychothérapie auprès des patients atteints de cancer. / Cancer patients experience extreme conditions of existence requiring a specific form of psychotherapy. The cancer and essential anticancer treatments together form the cancerous situation, invaded by the cancer’s violent, processual logic. This situation can constitute a sea change in the subject’s life, sweeping away their most firmly held convictions and the most deeply rooted foundations of their narcissistic identity and character. The subject is at major risk of suffering a breakdown. In addition, the ‘actual’ trauma draws strength from the revival of primary traumas up until now extinguished. Their return takes the form of hallucinatory sensations producing states of body and perception of the external world psychologically unrepresentable. The subject sees and experiences themself passively, without really being capable of feeling affected. Deadly dullness, inertia and pain dominate or, on the contrary, the subject feels vividly alive, hypersensitive, invaded and persecuted, at the risk of bursting. The world essentially revolves around this bipolarity, which the radical operational defence system covers in whiteness. It throws its mantle over the world, relationships, objects, affects and the subject’s body. Sometimes nothing can touch the subject at all, and their psyche is reduced to its archaic core, at the edge of psyche-soma. The cancer eradicates subjectivity, steeling away the active principle of primal logic. This sometimes lasting state of white melancholy is but one phase in a polymorphic melancholic processuality. This force dominates the subject’s life, with a tendency either to proto-melancholy or proto-mania, which replace the affective world by a propensity to inertia or psychomotricity. The aim of melancholy work is to revive the deadlocked capacity for identification. We will examine the specific use of transference and, in particular, the key implementation of a basic formal transference. This works based on the dual primal activation of formal signifiers shared by the therapist and their patient. The therapist may be subject to motions of lethargy and psychocorporal excitations, plunging the therapeutic relationship into crepuscular states, relative to the cancer and to the return of primary traumas. We will look at how the principle aim of psychotherapy is the psychological use, and not eradication, of the cancer object, as a means of forging the conditions rendering the therapeutic context feasible: allow the representation of states of body, restore symbolisation, imagination and recourse to unconscious fantasy. Together, these form the essential basis of psychotherapy for cancer patients.