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Le Japon, détruit par une guerre mal combattue, élevé au rang de puissance mondiale, récemment touché par des phénomènes naturels et artificiels est une nation profondément reconnue dans le monde entier bien qu’incomprise, victime de son exceptionnalisme, aujourd'hui doit se poser une vieille question. Le Japon fera-t-il partie de la communauté internationale en tant que membre actif ? La participation du Japon dans le monde a été étroitement définie et limitée à celle d'un commerçant et son image soutenue par une culture unique autoproclamée font que ces éléments sont aujourd'hui mis à l'épreuve. La dépendance fondamentale du trader/commerçant basée sur des valeurs strictement culturelles afin d’atteindre le succès escompté peut aujourd'hui s’avérer insuffisante pour s’assurer une survie dans un monde globalisé. Ainsi, autant les japonais que les étrangers questionnent la validité des outils culturels qui ont permis de réussir jusqu'ici telle que la loyauté dans l'avenir du commerce mondial / Japan, destroyed by an ill-fought war and risen to world power and yet again recently broken by natural and man-made phenomena, a nation intensely recognized the world over yet misunderstood, victim of its own exceptionalism, today needs to ask an old question. Will Japan participate in the international community as a full active member? Japan’s involvement with the world was narrowly defined and confined to that of a trader and its image sustained by a self-proclaimed unique culture and all these today are put to the test. The trader’s fundamental reliance on strictly cultural values to achieve success may today be insufficient to sustain their survival in a globalized world. Thus, the Japanese as well as foreigners question the validity of hitherto successful cultural tools such as loyalty in the context of globalized commerce

This qualitative research has been performed at Saab Dynamics with the purpose to analyze how resources are used in Saab to improve their processes and increase their market share. The theory used is founded in IMP theory with the implication that companies must move their focus from only considering internal resources into using their network. To analyze the different types resources in the network the 4R model has been used and adopted to two different cases at Saab Dynamics. The first case is about Saabs procurement of one of its suppliers, ACAB, and the second case is about a Country Xs procurement of the man-portable air-defense system RBS 70 NG. To gather data about the cases interviews has been performed with employees at Saab as well as other stakeholders. The result from these interviews were then analyzed based on the 4Rs, answering the questions: What Products are involved in the product development?  Which Production Facilities are involved in the product development? Which Business Units are involved in the product development? What Business relationships are involved in the product development? Once the resources were analyzed and compared to separately, the following question was answered: How have resources been combined to expand and strengthen the network? The result from the research showed that Saab has a great focus on its suppliers and how they should structure the network for the best potential end-result. In the first case, the procurement resulted in factors such as shorter lead-times, smoother processes and better quality products. The second case showed that Business Relationship resources such as trust played a great part in the procurement. To grow a stronger Business Relationship, Saab used a supplier in Country X which in turn also ended up being a part of the creation of a new innovative component.  The end discussion is about the benefits that the procurement of ACAB and weather this could be used as a way for Saab to expand their network while also gaining more control over the Supply Chain. This is something that goes against modern-day literature which often argue that the opposite often is to prefer. In the end there is also a short ethical section with the aim to examine why people chose to work in an industry like Saab Dynamics. To gather the data a few interviews were made with the end result that the respondents believe that the industry is necessary for the protection of Sweden and that it “is a human right to feel safe”.

Made available in DSpace on 2015-04-14T13:48:00Z (GMT). No. of bitstreams: 1 450036.pdf: 1416053 bytes, checksum: bca22f18969e9a6f832e9171f7743fae (MD5) Previous issue date: 2013-08-02 / This dissertation aims to analyze the performance of Francisco Adolfo de Varnhagen as a diplomat in the republics of Peru, Chile and Ecuador from 1863 to 1865. In this period, the brazilian diplomat had engaged in important events like the American Congress of Lima in 1864 and the Hispanic South American war, which put Spain versus Peru, Chile, Ecuador and Bolivia between 1865 and 1866. Looking after to maintain a positive image of the Empire among its neighbors, Varnhagen acted at a time of reorientation of imperial foreign policy throughout the nineteenth century: from Europe to America. His diplomatic activity was analyzed under the light of his values of truth, justice and fairness, also business of his historian craft. From the exposition of these principles dear to the historian-diplomat, the work follows his diplomatic trajectory analyzing the republics of the Pacific. / Essa disserta??o tem como objetivo analisar a atua??o de Francisco Adolfo de Varnhagen como diplomata nas rep?blicas do Peru, Chile e Equador entre 1863-1865. Neste per?odo, o diplomata brasileiro participou de importantes epis?dios como o Congresso Americano de Lima de 1864 e a guerra hispano-sulamericana, que colocou Espanha versus Peru, Chile, Equador e Bol?via entre 1865 e 1866. Obrando por manter uma imagem positiva do Imp?rio entre seus vizinhos, Varnhagen insere-se em um momento de reorienta??o da pol?tica externa imperial ao longo do s?culo XIX: da Europa ? Am?rica. Sua atua??o diplom?tica foi analisada tendo em vista seus valores de justi?a, verdade e imparcialidade, moldadores de seu of?cio historiador. A partir da exposi??o destes princ?pios do historiador-diplomata, o trabalho segue analisando sua trajet?ria diplom?tica nas rep?blicas do Pac?fico.

Submitted by Sandra Pereira (srpereira@ufrrj.br) on 2016-10-21T13:00:27Z No. of bitstreams: 1 2015 - Frederico Antonio Ferreira.pdf: 1988637 bytes, checksum: 619129e2ef8f27db8d320f7ed5ad0bd6 (MD5) / Made available in DSpace on 2016-10-21T13:00:27Z (GMT). No. of bitstreams: 1 2015 - Frederico Antonio Ferreira.pdf: 1988637 bytes, checksum: 619129e2ef8f27db8d320f7ed5ad0bd6 (MD5) Previous issue date: 2015-12-18 / The dissertation seeks to address the Foreign Policy II reign for Portuguese colonies in Africa, especially Angola and surrounding areas during the 1850s and 1860s, during which the traditional historiography considers to be of little or no contact. With the use of documents of Brazilian, Portuguese and British foreign ministries, as well as records written by Africans, this dissertation focuses on the indictment of participation of Brazilian General Consul, the doctor Saturnino de Sousa e Oliveira in the protests engendered by Prince Nicholas de ?gua Rosada e Sardonia, the Kingdom of Congo against the interference of the Portuguese crown in succession process in that him, which took place between 1858-1860, as well as in his murder. Showing that despite the end of the slave trade in 1850 after the Brazilian imperial state sought to maintain economic and political ties in Portuguese Africa despite the strengthening of the Portuguese Colonial State in the region and the growing presence of other European countries. / A disserta??o busca tratar da Pol?tica Externa do II Reinado para as col?nias portuguesas na ?frica, especialmente Angola e adjac?ncias, durante as d?cadas de 1850 e 1860, per?odo no qual a historiografia tradicional considera como sendo de pouco ou nenhum contato. Com a utiliza??o de documentos das chancelarias brasileira, portuguesa e brit?nica, assim como de registros escritos por africanos, esta disserta??o foca na acusa??o de participa??o do c?nsul geral brasileiro, o m?dico Saturnino de Sousa e Oliveira nos protestos engendrados pelo pr?ncipe Nicolau de ?gua Rosada e Sard?nia, do Reino do Congo, contra a interfer?ncia da coroa lusitana no processo sucess?rio no referido Reino, ocorrido entre 1858-1860, assim como em seu assassinato. Mostrando que apesar do t?rmino do tr?fico de escravos ap?s 1850 o Estado imperial brasileiro buscava manter v?nculos econ?micos e pol?ticos na ?frica Portuguesa apesar do fortalecimento do Estado Colonial portugu?s na regi?o e da presen?a crescente de outros pa?ses europeus

Submitted by Sandra Pereira (srpereira@ufrrj.br) on 2017-01-30T15:02:42Z No. of bitstreams: 1 2016 - Eduardo Belleza Abdala Miranda.pdf: 2931175 bytes, checksum: a60d654c2199468c575faab57666ab27 (MD5) / Made available in DSpace on 2017-01-30T15:02:42Z (GMT). No. of bitstreams: 1 2016 - Eduardo Belleza Abdala Miranda.pdf: 2931175 bytes, checksum: a60d654c2199468c575faab57666ab27 (MD5) Previous issue date: 2016-04-25 / This work aims to analyze the political-religious actions of the Roman Emperor Flavius Claudius Julian (361 ? 363 AD), known as ?the Apostate?. To comply with the proposal of the dissertation, will be need to understand a little about the period in which Julian ruled Rome, known as Dominato. From a periodization suggested in this paper, we seek to identify the characteristics of the political system and the importance of such research for the analysis of Julian's empire. Then we will make a brief biographical research on the sovereign comprising all his philosophical, political and religious formation, so we can understand densely their political and religious goals to become emperor. We used as the main source a hymn in devotion to the sun god, Helios, designed by Julian in Greek and translated into English by Wilmer Wright. Within the dynamics of research, the work seeks to avoid its hypothesis that the emperor followed the god Mithras, solar deity Indo-Iranian. The dissertation presents an analysis of the two deities separately, so you can identify which Julian followed suit. Made these studies, will we can reach the main hypothesis of this study was to identify the political transformation that Julian sought to achieve from a religious perspective based on the solar-worship / O presente trabalho tem por objetivo analisar as a??es pol?tico-religiosas do imperador romano Fl?vio Cl?udio Juliano (361 ? 363 d. C.), conhecido como ?o ap?stata?. Para cumprir com a proposta da disserta??o, ser? preciso compreender um pouco sobre o per?odo no qual Juliano governou Roma, conhecido como Dominato. A partir de uma periodiza??o sugerida neste texto, buscamos identificar quais as caracter?sticas desse sistema pol?tico e qual a import?ncia dessa investiga??o para a an?lise do imp?rio de Juliano. Faremos, ent?o, uma breve pesquisa biogr?fica sobre o soberano, compreendendo toda sua forma??o filos?fica, pol?tica e religiosa, para que, assim, possamos compreender densamente seus objetivos pol?tico-religiosos ao se tornar imperador. Utilizamos como fonte principal um hino em devo??o ao deus do Sol, H?lios, elaborado em grego por Juliano e traduzido para o ingl?s por Wilmer Wright. Dentro da din?mica da pesquisa, o trabalho busca se desvincular da hip?tese de que o imperador seguia o deus Mitra, divindade solar indo-iraniana. A disserta??o prop?e uma an?lise das duas divindades separadamente, para que seja poss?vel identificar qual delas Juliano seguia de fato. Feito estes estudos, poderemos chegar a principal hip?tese deste trabalho: identificar a transforma??o pol?tica que Juliano procurava realizar a partir de uma perspectiva religiosa com base no culto solar

Female veterans' combat exposure to trauma places them at risk for developing posttraumatic stress disorder (PTSD), which has consequences for healthful reintegration to family and civilian life. Previous research found that wives who provide continuous care to male veterans with PTSD experience symptoms of psychological distress; however, little research has been conducted on the influence of female veterans' PTSD on their intimate male partners' (IMPs) psychological well-being. A multivariate correlational design was used to examine the influence of female veteran PTSD on psychological distress and relationship quality in IMPs. The couples' adaption to traumatic stress model was used as the theoretical framework. The research questions examined (a) the difference between female veterans with and without PTSD on the length of time in the relationship, combat experience, the total number of deployments, and IMP psychological distress and (b) the influence of female veterans' combat experience, PTSD, and IMP psychological distress on relationship quality. A sample of 71 IMPs between the ages of 18 and 65 provided survey research data on the variables of interest. Psychological distress, number of partner deployments, and length of time in relationship discriminated significantly between IMPS whose partners were diagnosed with PTSD, not diagnosed, or did not know about the PTSD diagnosis. The regression results revealed that the psychological distress of IMPs and the number of partner deployments positively predicted relationship quality. Attention to female veterans and their families can contribute to increased retention of female service members in the Army and successful integration into family and civilian life.

Les médicaments thiopuriniques que sont l'azathioprine, la 6-mercaptopurine et la 6-thioguanine sont utilisés depuis des décennies pour leurs propriétés cytotoxiques et immunosuppressives dans le traitement de certaines leucémies, de maladies inflammatoires chroniques ou auto-immunes ainsi que dans la prévention du rejet de greffe. Certains patients, traités par des doses conventionnelles de ces molécules, développent cependant des effets indésirables parfois très sévères. Le déficit d'activité, d'origine génétique, de la thiopurine S-méthyltransférase (TPMT), enzyme impliquée dans le métabolisme des thiopurines, constitue l'un des facteurs majeurs de la myélotoxicité de ces médicaments. La détermination du phénotype TPMT par génotypage, qui est une mesure préventive avant l'introduction d'un traitement thiopurinique, repose sur l'identification des mutations inactivatrices les plus fréquentes du gène TPMT. Une partie de ce travail a consisté en l'analyse fonctionnelle de quatre variants alléliques rares du gène TPMT dans un système d'expression hétérologue, la levure S. cerevisiae. Le caractère non-fonctionnel de deux d'entre eux a ainsi été démontré. Cependant, le déficit d'activité de la TPMT ne permet d'expliquer qu'environ 30 % des cas de myélotoxicité sous thiopurines, ce qui laisse supposer l'existence d'autres anomalies génétiques affectant d'autres gènes impliqués dans la réponse de l'organisme à ces molécules. Ainsi, nous avons étudié le polymorphisme génétique de deux autres protéines candidates, celui de l'inosine monophosphate déshydrogénase de type 2 (IMPDH2), enzyme-clé de la formation des métabolites actifs des thiopurines, et celui de la RhoGTPase RAC1, qui est l'une des cibles pharmacologiques de ces molécules. Certains des polymorphismes que nous avons identifiés dans ces deux gènes semblent affecter in vitro l'expression et/ou l'activité de ces protéines et pourraient, par conséquent, contribuer aux variations inter-individuelles de réponse aux thiopurines

L?????tude de l???iconoclasme byzantin, cette crise th??ologique ayant pour cause l???essor du culte associ?? aux images religieuses, a ??t?? un exercice ardu pour les historiens. En effet, les maigres sources disponibles pour cette p??riode sont toutes favorables au culte des images. Bien qu?????crite par un iconodoule convaincu et hostile aux empereurs iconoclastes, la Chronographie de Th??ophane le Confesseur ne m??rite pourtant pas ses ??tiquettes contemporaines de pro-iconophile et d???anti-iconoclaste. Le pr??sent m??moire propose donc de revoir et de nuancer les ??crits de Th??ophane en ce qui a trait au pouvoir imp??rial. Il s???agira de d??montrer que la place des empereurs sur l?????chiquier th??ologique n???a aucune influence sur la repr??sentation du pouvoir, voire et de ceux qui l???exercent, dans la Chronographie. En effet, une analyse rigoureuse des empereurs de la p??riode iconoclaste (717-780) et de la p??riode iconodoule (780-815) prouvera que pour Th??ophane, rien n???est absolu : les iconoclastes ne sont pas d??pourvus de vertu et les iconodoules peuvent agir de fa??on tyrannique. La Chronographie propose ainsi une image complexe du pouvoir imp??rial, qui oblige ?? reconsid??rer les fronti??res entre l??gitimit?? imp??riale et tyrannie. -- The study of Byzantine iconoclasm, a theological crisis caused by the emergence of religious practices centered on divine images, has proven to be a difficult endeavor for historians. Indeed, the few available sources which discuss this period are clearly favorable to this cult of images. Despite having been written by a convinced iconodule who was also hostile to iconoclastic emperors, the Chronicle by Theophanes the Confessor should not be labelled as purely pro-iconophile and anti-iconoclastic. As such, the present thesis will seek to review and relativize the writings of Theophanes with regards to imperial power. This will attempt to demonstrate that in the Chronicle, the place of emperors on the theological playing field has no impact on the representations of power or those who exert it. In fact, a rigorous analysis of emperors from the iconoclastic period (717-780) as well as the iconodule period (780-815) will show that inTheophanes??? mind nothing is absolute: iconoclasts are not devoid of virtue and iconodules can be tyrannical. Hence, the Chronicle presents a complex image of imperial power, one which demands a reconsideration of the boundaries between imperial legitimacy and tyranny.

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2016-02-29T22:55:50Z No. of bitstreams: 1 AdrianaCostaDeSouzaMartinsCamara_TESE.pdf: 3396087 bytes, checksum: b8e35eee4bb9ca8e4392251f05ab7935 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2016-03-02T19:21:41Z (GMT) No. of bitstreams: 1 AdrianaCostaDeSouzaMartinsCamara_TESE.pdf: 3396087 bytes, checksum: b8e35eee4bb9ca8e4392251f05ab7935 (MD5) / Made available in DSpace on 2016-03-02T19:21:41Z (GMT). No. of bitstreams: 1 AdrianaCostaDeSouzaMartinsCamara_TESE.pdf: 3396087 bytes, checksum: b8e35eee4bb9ca8e4392251f05ab7935 (MD5) Previous issue date: 2015-02-26 / Altera??es epiteliais observadas em queilites act?nicas (QA) e carcinomas epiderm?ides de l?bio inferior (CELI) s?o causadas principalmente pela exposi??o cr?nica aos raios ultra-violetas (UV) e s?o estudadas usando diferentes marcadores imuno-histoqu?micos procurando avaliar o processo da carcinog?nese. O objetivo deste estudo foi avaliar comparativamente a express?o das prote?nas Ki-67 e IMP-3 em QA e CELI a fim de contribuir com informa??es adicionais sobre a carcinog?nese em l?bio inferior. Foram estudados 33 casos de QA e 33 casos de CELI, sendo analisadas as caracter?sticas cl?nico-patol?gicas e a imunoexpress?o do Ki-67 e IMP-3. A an?lise imuno-histoqu?mica do Ki-67 se deu atrav?s da determina??o do ?ndice de prolifera??o (IP) e subsequente classifica??o dos casos de acordo com os escores : 0 (0% de c?lulas positivas), +1(?30%), +2 (>30% a ?60%) e +3 (>60%). Para aplica??o dos testes estat?sticos os casos foram classificados em: sem marca??o (escore 0), baixa express?o (escore +1) e alta express?o (escores +2 e +3). Para a express?o do IMP-3, foi estabelecido o percentual de c?lulas epiteliais imunomarcadas, sendo atribu?dos os escores: 0 (correspondeu a 0%), +1 (at? 30% das c?lulas positivas); +2 (entre 30% a 60% de c?lulas imunomarcadas) e +3 (acima de 60% das c?lulas positivas). Foram utilizados os testes estat?sticos Qui-quadrado de Pearson, Mann-Whitney e Wilcoxon. O n?vel de signific?ncia adotado foi de 5%. A maioria dos caos de QA foi do sexo masculino (78,8%), com m?dia de idade de 50 anos e dos casos de CELI tamb?m predominou o sexo masculino (69,89%) com m?dia de 62 anos. O Ki-67 se expressou em todos os casos de QAs bem como nos casos de CELI, predominando nas duas les?es o escore 2, correspondendo a 81,8% dos casos nas QAs e 54,5% nos CELI. A express?o do IMP-3 nas QAs ocorreu em 72,7% dos casos, com predomin?ncia em 36,3% dos casos do escore 1. J? nos CELI o IMP-3 se expressou em 60,6% dos casos, com predomin?ncia em 27,3% dos casos do escore 3. Estes resultados nos permite concluir que a express?o do IMP3 e da atividade proliferativa s?o eventos precoces na carcinog?nese de l?bio inferior independente do estado da altera??o. / Epithelial changes observed in actinic cheilitis (AC) and squamous cell carcinoma of the lower lip (LLSCC) are mainly caused by chronic exposure to ultraviolet rays (UV) and are studied using different immunohistochemical markers trying to evaluate the process of carcinogenesis. The objective of this study was to comparatively evaluate the expression of Ki-67 proteins and IMP-3 in AC and LLSCC to contribute with additional information on carcinogenesis in lower lip. A total of 33 cases of AC and 33 cases of LLSCC were studied, analyzed the clinical and pathological features and immunostaining of Ki-67 and IMP-3. Immunohistochemical analysis of Ki-67 was made through the determination of the proliferation index (PI) and subsequent classification of the cases according to the scores: 0 (0% positive cells) +1 (?30%) + 2 (> 30% and ?60%) and +3 (> 60%). For statistical tests cases were classified as unmarked (score 0), low expression (score +1) and high expression (scores +2 and +3). For the expression of IMP-3, the percentage of immunostained epithelial cells was established, and assigned scores: 0 (corresponding to 0%), +1 (up to 30% of positive cells); +2 (From 30% to 60% of immunostained cells) and +3 (over 60% of positive cells). Statistical tests chi-square test, Mann-Whitney and Wilcoxon were used. The significance level was 5%. Most AC chaos was male (78.8%) with mean age of 50 years and cases of LLSCC also were male (69.89%) with an average of 62 years. The Ki-67 was expressed in all cases of AC and in cases of LLSCC, predominantly in the two injuries the score 2, corresponding to 81.8% of cases in ACs and 54.5% in the CELI. The expression of IMP-3 in ACs occurred in 72.7% of cases, predominantly in 36.3% of LLSCC cases score 1. Already in the IMP-3 was expressed in 60.6% of cases, especially in 27.3% of the score of the cases 3. These results allow us to conclude that the expression of IMP3 and proliferative activity are early events in carcinogenesis independently lower lip state of change.