The main objective of this study was to evaluate the current situation of selected agro-tourist farms Benešovsku in terms of their structure, collaboration with local action groups (LAGs), the method and the effectiveness of their marketing. The theoretical approach was the study of literature, including Internet resources. The theoretical part were subsequently confronted with the information obtained in the empirical part - conducted interviews with the owners and operators of agro-tourist farms in the monitored region and representatives of local action groups. Based on the information and suggestions in the final part of the thesis formulated recommendations. The aim to optimize the marketing strategy of agro-tourist farms Benešovsku.

The main objective of this thesis is to evaluate the impact of Structural Funds of the European Union on social-economic espects of the Local Action Group Třeboňsko and to describe the means and rules for obtaining support from structural funds ? in particular the conditions for drawdown of subsidies from the Leader programme. I contacted representatives of municipalities with a questionnaire survey and asked about satisfaction with the implementation of structural funds, sukces in drawing, purpose for used resources, their vision for the future. Findings are summarized in the tables nad graphs. Results of the survey evaluated and processed. Custom design changes and recommendations.

L’allergie de contact est une pathologie de la peau particulièrement répandue dans les pays industrialisés. Aucune thérapie ne permet actuellement de la soigner et seule l’éviction de l’allergène permet de la prévenir. Historiquement, l’évaluation du potentiel sensibilisant des molécules mises sur le marché a toujours été réalisée au moyen de tests sur l’animal. Cependant, le champ d’action de ces tests est aujourd’hui limité en raison de la nouvelle législation européenne sur les cosmétiques. Dans ce contexte, le développement de méthodes alternatives ne reposant pas sur l’utilisation d’animaux devient capital. L’allergie de contact repose sur une étape chimique clé : la formation d’un complexe antigénique allergène-protéine capable d’activer le système immunitaire cutané. Le but de ce travail de thèse a été d’étudier le comportement in situ d’allergènes au sein d’épidermes reconstruits de type SkinEthic®. A l’aide d’une technique d’analyse non invasive, la spectroscopie RMN HRMAS, il a été possible de suivre le devenir de différents allergènes, de leur éventuelle activation par voie métabolique, jusqu’à leur fixation sur les protéines épidermiques. / Contact dermatitis is a skin pathology particularly prevalent in industrialized countries. No therapy currently exists and only complete avoidance of the particular allergen can prevent an allergic reaction. Historically, the assessment of skin sensitisation potential of molecules placed on the market was always carried out by animal testing. However, the scope of this testing method is now limited by the new European cosmetics legislation. In this way, the development of alternative methods, not based on animal experimentation, become an important issue. Contact dermatitis results of a chemical key step: the formation of an antigenic complex allergen-protein complexe able to activate the cutaneous immune system. The aim of this PhD work was to study the in situ behaviour of allergens in reconstructed human epidermis (SkinEthic® model). By using an appropriate non-invasive analysis technique, HR-MAS NMR spectroscopy, it has been possible to study the mode of action of different allergens, from their possible activation through the metabolic pathway to the binding with epidermal proteins.

Submitted by Biblioteca Central (biblioteca@unicap.br) on 2017-10-16T21:10:41Z No. of bitstreams: 1 dissertacao _roberval_rocha_ferreira_filho.pdf: 879757 bytes, checksum: 1529f041e11cc0d45b9d37d2d2f097aa (MD5) / Made available in DSpace on 2017-10-16T21:10:41Z (GMT). No. of bitstreams: 1 dissertacao _roberval_rocha_ferreira_filho.pdf: 879757 bytes, checksum: 1529f041e11cc0d45b9d37d2d2f097aa (MD5) Previous issue date: 2009-01-02 / With the advent of mass society, marked by high litigiosity and complexity of the social relations, the traditional techniques of conflict’s resolutions have revealed insufficient to protect the social peace. As a result of this, the common law old procedural institute of class actions resurged with force. In the last decades, the class action institute has been spread in all world as an effective technique to combat the litigiosity and to improve the access of justice. Absorbed by almost all the legal systems, the class actions had operated significant changes in the protection of the metaindividual rights. However, in the Brazilian legal system, although the recent legislative advances, the use of class actions has not achieved all the legal subsystems, as the tax law system, where the phenomenon of the litigiosity, of the legal relationships complexity, and the mass actions are rule. The analysis of this situation, including the necessity of the use of this type of legal action to strengthen citizenship and to mitigate the litigiosity in the relations Statetaxpayer, is the target of the present work. / Com o advento da “sociedade de massa”, marcada pela forte carga de litigiosidade e complexidade das relações sociais, as técnicas tradicionais de resolução de conflitos mostraram-se insuficientes para resguardar a paz social. Nesse ambiente, resurgiu com força o antigo instituto processual das class actions, oriundas da tradição common law, que, em décadas recentes, espalhou-se pelo mundo todo como técnica efetiva de combate à litigiosidade e de acesso à justiça. Absorvidas por quase todas as famílias do direito, as ações coletivas operaram mudanças significativas na proteção dos chamados direitos metaindividuais. Entretanto, sua utilização no Brasil, apesar dos avanços legislativos recentes, ainda não abraçou porções do direito, como o tributário, onde o fenômeno da litigiosidade, da complexidade das relações jurídicas, e da massividade são regra. A análise desse panorama, e da necessidade desse tipo de tutela para reforçar noções de cidadania e esvaziar a litigiosidade contida nas relações Estado-contribuinte é o escopo do presente trabalho.

Um conjunto de reflexões teóricas sobre as incompatibilidades entre a Ordem Inter-nacional pós-Guerra Fria e as categorias estruturantes dos paradigmas analíticos dominantes, esta tese procura também apontar dados empíricos e listar questões a serem compreendidas por um novo modo de produção de conhecimentos em rela-ções internacionais. Ela critica tanto os paradigmas unidimensionais, principalmente os de corte liberal e leno-stalinistas, quanto os bidimensionais, de inspiração realista e racionalista, indicando que ambos formam redes conceituais baseadas numa dialé-tica dicotômica, que reduz a complexidade do internacional e do estrangeiro a um olhar e interesse nacionais. Sugere que o sistema internacional e os subsistemas regionais, como objetos de estudo, não se reduzem a suas unidades, constituindo uma terceira dimensão, ou zona cinzenta, cuja conformação, para ser compreendida depende da análise integrada dos fenômenos da guerra, das globalizações e do for-talecimento do Estado. Completando as sugestões para o debate e a formulação de conceitos interpretativos mais abrangentes, além de alguns neologismos, esta tese constrói algumas tipologias compreensivas. O autor adverte, contudo, que essas formulações têm o propósito de ilustrar a análise, não de fechar a discussão com um modelo acabado. / A set of theoretical reflections on the contradictions between the post-Cold War inter-national order and the structuring categories of the prevailing analytical paradigms, this thesis also tries to point to empirical data and list questions to be understood by a new way of producing knowledge in international relations. It criticizes both one-dimensional paradigms, mainly those in the liberal and Lenin-Stalinist model, and two-dimensional paradigms of realistic and rational inspiration, showing that both of them build conceptual networks based on the dialectics of dichotomy, which reduces the complexity of being international and foreign to a national vision and interest. The work also suggests that the international system and the regional subsystems, as objects of study, are not limited to their units, making up a third dimension, or grey zone, whose configuration can only be understood through an integrated analysis of the war phenomena, globalization and the strengthening of the State. By making suggestions for the debate and formulation of more comprehensive interpretation concepts, in addition to some neologisms, this thesis builds some broad typologies. However, the author warns that these formulations have the purpose of illustrating the analysis, not closing the debate on a finished model.

This thesis is dedicated to creating a new system with capabilities to create new generic, autonomous strategy computer game controlling elements based on multi-agent systems with social, intelligent decision-making and learning skills. Basic types of strategy games and problems of their playing will be introduced, along with currently used methods of intelligent game AI development. This thesis also presents design and implementation of the new system, working model for a specific game and results obtained while testing it.

The dissertation thesis deals with the design of the concept and implementation of models of electrical power system elements with regard to the potential of the use of computer programs – simulations. The solution of the thesis focuses on the compliance simulations of power-generating modules according to RfG (Requirements for Generators), as a document which setting out the requirements for the connection of power-generating facilities and also focuses on the issue of smart grids and MAS (Multi-Agent Systems) respectively. The framework of the thesis is thus defined by the area of requirements for power-generating modules according to legislative requirements (not only RfG, but also related standards incl. DSC (Distribution System Code), CSN EN 50438 and CSN EN 50549), requirements for agent functionalities and power-generating module abilities to operate in synchronous and island operation, including transitions between them, the process of synchronization (phasing) and communication between the individual elements of the power system.

Les Réseaux de Petri (RdP) sont actuellement les approches les plus prometteuses pour modéliser et vérifier les systèmes complexes tels que les Systèmes Multi Agents (SMA). De nombreuses solutions ont été proposées pour remédier aux problèmes de communication, de coordination et d’interaction entre les Agents. Cependant, il n’existe aucune en mesure de traiter, à la fois les aspects structurels et comportementaux, du moins à notre connaissance. La thèse s'intéresse à la problématique de modélisation formelle et de vérification automatique et semi-automatique de propriétés pour les Systèmes Multi Agents. Plus précisément, l'objectif consiste à proposer un nouveau modèle formel original basé sur les réseaux de Petri, les Réseaux de Petri à Agents (RdPA), qui permettent d’exprimer de manière consistante et plus précise les systèmes Multi Agents. Il s’intéresse de plus à l’extension de ce modèle aux fins de modéliser la migration des agents dans le cadre des systèmes à agents mobiles. Cette classe de modèle permet de s’intéresser à la vérification formelle de propriétés classiques comme notamment la vivacité ou l’absence d’interblocage dans le cadre des Systèmes Multi-Agent. / Petri nets (PN) are currently the most promising approaches to model and to verify complex systems such as Multi Agent Systems (MAS). Several solutions have been proposed to solve the problems of communication, coordination and interaction among Agents. However, to best of our knowledge, none of this solution has able to handle both aspects: structural and behavioral. The thesis focuses on the problem of formal modeling and automatic and semi-automatic verification of properties in Multi Agent Systems. More specifically, the objective is to propose a new original formal model based on Petri nets, Agents Petri nets (APN), which express consistently more accurate a Multi Agent Systems. There is growing interest in the extension of this model for modeling the migration of Agents within the mobile Agent systems. This class of model allows focusing on the formal verification of classical properties such as alertness or absence of deadlock in the context of Multi Agent Systems.

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