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Sintese e avalia??o de atividade tripanocida de novos heterociclos da classe dos 1,2,4-OXADIAZ?IS, derivados e an?logos da amida natural piperina. / SYNTHESIS AND EVALUATION OF TRIPANOCIDAL ACTIVITY OF NEW HETEROCYCLES OF THE 1,2,4-OXADIAZIAL CLASS, DERIVATIVES AND ANALOGS OF THE NATURAL AMID PIPERINA.Soares, Breno Almeida 25 September 2009 (has links)
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Previous issue date: 2009-09-25 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior, CAPES, Brasil. / This work is part of a research project which investigates the utilization of abundant
and accessible natural products in the synthesis of new molecules with potential activity
against Chagas? disease. Recent studies carried out in our laboratory showed activity
against Trypanosoma cruzi for piperine, a major component of Piper nigrum and for a
series of its derivatives and analogues. Using bioisosterism as a strategy for molecular
modification, we describe here the design, synthesis and antiparasitic evaluation of
class of derivatives of 1,2,4-oxadiazole. The key step of the synthetic strategy used
involved the SNAC reaction of the benzamidoxima with acid chlorides followed by
cyclization, which allowed the preparation of eight new 1,2,4-oxadiazole The evaluation
of the toxic activity of these new derivatives against epimastigote form of T. cruzi
confirmed the bioisosteric relationship between the natural amide and the new products
prepared, showing the oxadiazole 55 direct derived from piperine, as the most active
compound in the series. / Este trabalho se insere numa linha de pesquisa que visa a utiliza??o de produtos
naturais abundantes e access?veis na s?ntese de novas mol?culas com potencial atividade
anti-chag?sica. Estudos recentes em nosso laborat?rio demonstraram a atividade
antiparasit?ria da piperina e de uma s?rie de derivados e an?logos sobre o Trypanosoma
cruzi, agente etiol?gico da doen?a de Chagas. Utilizando o bioisosterismo como
estrat?gia de modifica??o molecular, descrevemos aqui o planejamento, a s?ntese e a
avalia??o antiparasit?ria de derivados da classe dos 1,2,4-oxadiaz?is. A etapa-chave da
estrat?gia sint?tica utilizada envolveu a rea??o de SNAC da benzamidoxima com cloretos
de ?cidos, seguida de cicliza??o, que permitiu a prepara??o de oito novos 1,2,4-
oxadiaz?is. A avalia??o da atividade t?xica destes novos derivados contra a forma
epimastigota do T. cruzi confirmou a rela??o bioisost?rica entre a amida natural e os
novos derivados preparados, evidenciando o oxadiazol 55 derivado direto da piperina,
como o composto mais ativo da s?rie.
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Influ?ncia da densidade de semeadura do feijoeiro comum na incid?ncia de plantas espont?neas em sistema org?nico de produ??o / Influence of the sowing density of common bean on weed incidence in organic production systemSilva, Mara Alexandre da 29 August 2014 (has links)
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Previous issue date: 2014-08-29 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / Organic production is an alternative for family farmers where practices to reduce costs
and to preserve natural resources can add value to the product and improve quality of
life. The weeds can cause losses in crops, by reduction of income, increase in pests and
diseases, non uniformity in maturity and difficulties for harvesting. The objective of this
study was to evaluate the performance of common bean cultivars (Phaseolus vulgaris)
at different sowing densities regarding the incidence of weeds in organic production
system. Two field experiments were conducted in the Agroecological Production
Integrated System of 47 km in Serop?dica-RJ, in the years 2013 and 2014, in a
randomized block design with four replications. In 2013 a 4x3 factorial was used,
combining four cultivars (Ouro Negro, Manteig?o, Radiante and Apor?) and three
densities (8, 13 and 18 plants m-1 linear). In 2014 a 2x3 factorial was used, between two
cultivars (Manteig?o and Ouro Negro) and three treatments (13 plants m-1 with manual
cleaning of weeds, 13 and 18 plants m-1 without cleaning). To obtain the desired plant
population, 50% more seeds were sown in each treatment and plants were thinned 15
days after. Sampling was carried out at the flowering stage to assess biomass and
nodulation of bean and biomass of weeds, and at physiological maturity to evaluate
grain yield. In 2013, the largest shoot and root dry mass and number of nodules per
plant occurred in the density of 8 plant m-1. Increased planting density reduced the
number of pods per plant, with no effect of density on grain yield. The lower biomass of
weeds was observed at densities of 13 and 18 plant m-1, and also for cutivars Manteig?o
and Ouro Negro. In 2014, treatment with 13 plants m-1 with cleaning showed greater
dry mass of shoots and roots per plant. At flowering, treatment with 13 plants m-1
showed higher dry matter and number of weeds. The cultivar Ouro Negro showed
higher grain yield at density of 13 plants m-1 with cleaning, followed by 18 plants m-1,
with no differences between treatments for cultivar Manteig?o. The treatment with 18
plants m-1 showed lower mass of weeds at bean flowering, similar to the treatment with
13 plants m-1 with cleaning. Plots with cultivar Manteig?o had the highest dry matter of
weeds in the three density treatments. Grain yield did not differ significantly among
cultivars, ranging in 2013 from 1310 kg ha-1 for Apor? and 1409 kg ha-1 for Manteig?o,
and in 2014 of 1298 and 1419 kg ha-1 for Manteig?o and Ouro Negro. It is concluded
that increasing plant density reduced the incidence of weeds and did not affect grain
yield. It was also carried out a field trial in 2013 in family agricultural establishment in
the city of Teresopolis-RJ, in order to encourage the cultivation of special beans and to
experience economic and social strategies of reproduction. The experiment had a 4x2
factorial with four replications, using four cultivars (Apor?, Manteig?o, Radiante and
Valente) and two treatments (with and without commercial inoculant with rhizobia).
Grain yield of the four cultivars did not differ between the treatments in the absence and
presence of seed inoculation with rhizobia / A produ??o org?nica constitui uma alternativa para a agricultura familiar, onde pr?ticas
para diminuir os custos de produ??o e preserva??o dos recursos naturais agregariam
valor ao produto e qualidade de vida. As plantas espont?neas podem causar perdas em
cultivos, pela redu??o do rendimento, aumento de pragas e doen?as, desuniformidade na
matura??o e dificuldades na colheita. O objetivo deste trabalho foi avaliar o
desempenho de cultivares de feijoeiro comum (Phaseolus vulgaris) em diferentes
densidades de semeadura, com rela??o ? incid?ncia de plantas espont?neas em sistema
org?nico de produ??o. Foram conduzidos dois experimentos de campo no Sistema
Integrado de Produ??o Agroecol?gica do km 47, em Serop?dica-RJ, nos anos de 2013 e
2014, em blocos ao acaso com quatro repeti??es. Em 2013 foi utilizado esquema
fatorial 4x3, combinando quatro cultivares (Ouro Negro, Manteig?o, Radiante e Apor?)
e tr?s densidades (8, 13 e 18 plantas m-1 linear) e em 2014 utilizou-se esquema fatorial
2x3, entre duas cultivares (Manteig?o e Ouro Negro) e tr?s tratamentos (densidade de
13 plantas m-1 com limpeza manual de plantas espont?neas, densidades de 13 e 18
plantas m-1 sem limpeza). Para obten??o da popula??o desejada, foram semeadas 50%
mais sementes em cada tratamento, e 15 dias ap?s realizou-se desbaste. Foram efetuadas
amostragens no est?dio de flora??o para avalia??o de biomassa e nodula??o do feijoeiro
e da biomassa de plantas espont?neas, e na matura??o fisiol?gica para avalia??o do
rendimento. Em 2013, a maior massa seca de parte a?rea e raiz e n?mero de n?dulos por
planta ocorreu na densidade de 8 plantas m-1. O aumento da densidade de plantio
reduziu o n?mero de vagens por planta, sem efeito da densidade na produtividade de
gr?os. A menor massa de plantas espont?neas foi observada nas densidades de 13 e 18
plantas m-1, e com as cultivares Manteig?o e Ouro Negro. Em 2014, o tratamento com
13 plantas m-1 com limpeza apresentou maior massa seca de parte a?rea e raiz por
planta. Na flora??o, o tratamento com 13 plantas m-1 sem limpeza apresentou maior
massa seca e n?mero de espont?neas. A cultivar Ouro Negro apresentou maior produ??o
de gr?os no tratamento de 13 plantas m-1 com limpeza, seguida por 18 plantas m-1, sem
diferen?as entre tratamentos na cultivar Manteig?o. O tratamento com 18 plantas m-1
apresentou menor massa de espont?neas na flora??o do feijoeiro, similar a 13 plantas m-
1 com limpeza. A cultivar Manteig?o apresentou maior massa de espont?neas nos tr?s
tratamentos. A produ??o de gr?os n?o diferiu significativamente entre as cultivares,
variando em 2013 entre 1310 kg ha-1 para Apor? e 1409 kg ha-1 para Manteig?o, e em
2014 com 1298 e 1419 kg ha-1 para Manteig?o e Ouro Negro. Conclui-se que o aumento
da densidade de plantio reduziu a incid?ncia de plantas espont?neas e n?o afetou a
produtividade de gr?os do feijoeiro. Foi tamb?m conduzido um experimento de campo
em 2013 em estabelecimento agr?cola familiar no munic?pio de Teres?polis-RJ, com o
objetivo de incentivar o cultivo de feij?es especiais e vivenciar estrat?gias de
reprodu??o econ?mica e social. O experimento tinha esquema fatorial 4x2 com quatro
repeti??es, entre quatro cultivares (Apor?, Manteig?o, Radiante e Valente) e dois
tratamentos (com e sem uso de inoculante comercial de riz?bio). A produ??o de gr?os
das quatro cultivares n?o diferiu entre os tratamentos na aus?ncia e na presen?a de
inocula??o de sementes com riz?bio.
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Potencial de esp?cies locais na diversifica??o dos agroecossistemas, como culturas de cobertura, no manejo de plantas espont?neasFERREIRA, Liliane de Souza 09 August 2016 (has links)
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Previous issue date: 2016-08-09 / The management of weeds is complex and comprises a major component of the production cost of most cultures. Growing cover crops is one of the forms of management to reduce weeds competing. Agrobiodiversity, including the biota and the surrounding properties, constituting a cultural and natural capital able to provide ecosystem services. In this context, we developed a study to investigate the potential of wild species Crotalaria incana (rattlesnake rattle or Xique-Xique) and Diodia saponariifolia (Poaia the swamp), which occur in a nearby landscape the Atlantic Forest fragments in the River Basin region Guapi-Macacu-RJ, as part of sustainable agro-ecosystems, constituting strategy to reduce the use of herbicides and enhancing local biodiversity. This potential was assessed in C. incana through phenological studies of plant height, crown diameter, number of branches, presence of inflorescence and number of pods along the cycle and at different times, October, January, February and March. Also evaluated in its interaction with the climate and planting dates. It was found that the planting October C. incana had the longest growing season, low seed production. In the planting in February, the performance of C. incana was good in both parameters; while planting in March, C. incana demonstrated lower performance for mass production and seeds. Preliminary assessments of total biomass and macronutrients, indicate the potential of C. incana as a cover crop that needs to be better investigated. As for D. saponariifolia, a creeping species characterized as macrophyte, evaluations were made of soil coverage percentage after its introduction, compared to the most frequently dominant families in the system, Poaceae and Cyperaceae. Subsequently evaluated the seed bank behavior in this same area after being introduced (experimental area), compared to natural area, which was already established spontaneously. We observed a cooling populations of Poaceae and Cyperaceae after the introduction D. saponariifolia. The spontaneous seed bank revealed a reduction in the expression of these families, important competitors in the system. Possible allelopathic effect of D. saponariifolia in suppressing spontaneous, was evaluated by bioassay with the soil of the natural area where D. saponariifolia prevails spontaneously. In this ground sesame seeds were germinated Sesame indicu L. () in 15-cell trays 3 treatments (T1, T2, T3). T1, activated carbon was added to neutralize allelopathic effects harmful to the development of seedlings. T2, do not add anything. In T3 (control) used a soil adjacent area without the presence of individuals D. saponariifolia. There was no significant difference in the development of seedlings in 3 treatments, indicating no evidence of allelopathic effects of D. saponariifolia on Sesame germination. We can infer that the suppression of processes D. saponariifolia are only for "muffling". / O manejo de plantas espont?neas ? complexo e comp?e um dos principais componentes do custo de produ??o da maioria das culturas. O cultivo de plantas de cobertura ? uma das formas de manejo para redu??o das plantas espont?neas competidoras. Neste contexto desenvolveu-se um estudo com objetivo de investigar o potencial das esp?cies espont?neas Crotalaria incana (Xique-Xique) e Diodia Saponariifolia (Poaia do brejo), que ocorrem em uma paisagem pr?xima a fragmentos de Mata Atl?ntica, na regi?o da Bacia do Rio Guapi-Macacu-RJ, como parte integrante de agroecossistemas sustent?veis, constituindo estrat?gia para redu??o do uso de herbicidas e incremento da biodiversidade local. Este potencial foi avaliado em C. incana, atrav?s de estudos fenol?gicos de altura da planta, di?metro de copa, n?mero de ramos, presen?a de infloresc?ncia e n?mero de vagens ao longo do ciclo e em diferentes ?pocas Outubro, Janeiro, Fevereiro e Mar?o). Avaliou-se tamb?m sua intera??o com o clima e ?pocas de plantio. Constatou-se que no plantio de Outubro, C. incana teve o ciclo vegetativo mais longo, com pouca produ??o de sementes. J? no plantio em Fevereiro, o desempenho de C. incana foi bom em ambos par?metros; enquanto no plantio de Mar?o, C. incana demonstrou menor desempenho tanto para produ??o de massa como de sementes. Avalia??es preliminares de macronutrientes totais e biomassa indicam bom potencial de C. incana a ser melhor investigado. Quanto ? D. Saponariifolia, uma esp?cie rasteira caracterizada como macr?fita, foram feitas avalia??es de porcentagem de cobertura do solo ap?s sua introdu??o, comparando com as fam?lias mais frequentemente dominantes no sistema, Poaceae e Cyperaceae. Posteriormente avaliou-se o comportamento do banco de sementes nesta mesma ?rea ap?s ser introduzida (?rea experimental), comparando com ?rea natural onde j? estava estabelecida espont?neamente. Observou-se um arrefecimento das popula??es de Poaceae e Cyperaceae ap?s a introdu??o D. saponariifolia. O banco de sementes de espont?neas revelou uma redu??o na express?o destas fam?lias e de Asteraceae, importantes competidoras no sistema. Poss?vel efeito alelop?tico de D. saponariifolia na supress?o de espont?neas, foi avaliado atrav?s de biosensaio com o solo da ?rea natural, onde D. saponariifolia predomina espontaneamente. Neste solo foram germinadas sementes de Sesamo indicu L. (Gergelim) em bandejas de 15 c?lulas, com 3 tratamentos (T1,T2,T3). Em T1, adicionou-se carv?o ativado, que neutralizaria efeitos alelop?ticos prejudiciais ao desenvolvimento das pl?ntulas. Em T2, n?o se adicionou nada. Em T3 (controle) utilizou-se um solo da ?rea adjacente, sem presen?a de indiv?duos de D. saponariifolia. N?o houve diferen?a significativa no desenvolvimento das pl?ntulas nos 3 tratamentos, indicando n?o haver evid?ncias de efeitos alelop?ticos de D. saponariifolia na germina??o de Gergelim. Podemos inferir que os processos de supress?o de D. saponariifolia sejam apenas por ?abafamento?.
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Estudo comparativo de imaturos de d?pteros muscoides de import?ncia m?dica-veterin?ria e forense com base em caracteres morfol?gicos e moleculares / Comparative studies of muscoids diptera with medical-veterinary and forensic importance using morphological and forensic charactersMENDON?A, Paloma Martins 16 October 2014 (has links)
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Previous issue date: 2014-10-16 / CNPq / The Order Diptera is composed by about 153 thousand described species, but it is believed that the number of unknown species is much bigger. Adults and immature of some muscoid dipteran groups have little morphological differences, making the identification process more difficult. Besides, the available dichotomous keys are based on adults, but in the case of myiasis and cadaver colonization, only immature are found. These insects are known pathogen vectors, their larvae parasite humans and animais and they play an important role in forensic entomology. Therefore, the correct identification of these species is very important. This study aims to characterize features of medical, veterinary and forensic important dipteran species using two new approaches. The first chapter uses scanning electron microscopy which gives detailed information on the morphological characters that can help identify the immature forms of the flies. Immatures belonging to three muscoids with forensic and sanitary importance were studied using this methodology: Peckia (Eubaettcheria) cal/usar (Diptera: Sarcophagidae) (larvae and puparia), Luc?lia cuprina (larvae and puparia) e Cachliamyia macellaria (eggs, larvae and puparia) (Diptera: Calliphoridae). The size ofthe chorionic cells as well as the absence of spines at the posterior spiracle allowed to differentiate C. mace/faria from C. haminivarax, both myiasis causing species. The maxillary palp complex composed by a group of papillae inside a cavity seem to be specific to the subgenus Eubaeucheria. The anterior spiracular openings displaced in an irregular row are found exclusively in Sarcophagidae. The filiform spines at the anal segments are found only in the genus Lucilia. In the second chapter, barcading is used to provide a gene sequence database of medical, veterinary and forensically important Calliphoridae flies. This technique is based on the sequencing of a portion of the genome of the mitochondrial cytochrome oxidase l (cal) gene. Nine species of flies were collected in four regions in Brazil, corresponding to 346 specimens. Two other gene fragments ( elongation factor 1 alpha and white) were sequenced for the first time for some species. The barcade proposal was successfully achieved for Hemilucilia segmentaria, Hemi/ucilia semidiaphana, Chlarapracla idiaidea, Cachliamyia macellaria, Chrysamya megacephala and Chrysamya albiceps, for which the intraspecific variation was less than 3%. However, for Lucilia eximia, Chrysamya putaria and Chrysamya rufifacies, this methodology brought incipient results. Intraspecific variation among Lucilia eximia samples was 4.6%, suggesting that the threshold proposed should not be used for ali dipteran species without previous analysis of the studied group. Chrysamya putaria is polyphyletic according to nuclear and mitochondrial genes. In addition, a set of samples grouped with samples of C. albiceps and C. rufifacies. Therefore, more studies need to be clone to better explain these taxonomic problems. / A ordem Diptera ? composta por aproximadamente 153 mil esp?cies descritas, mas acredita-se que o n?mero de esp?cies ainda desconhecidas ? muito grande. Alguns grupos de d?pteros musc?ides possuem imaturos e adultos com poucas varia??es morfol?gicas, dificultando muito o processo de identifica??o. Al?m disso, as chaves dicot?micas existentes s?o baseadas nos adultos, entretanto, s?o os imaturos mais encontrados causando mi?ases ou colonizando cad?veres. Estes inselos s?o conhecidos vetores de pat?genos, suas larvas s?o parasitas de humanos e animais e apresentam papel importante como auxilio a entomologia forense. Assim, a correta identifica??o das esp?cies que desempenham estas fun??es ? muito importante. O presente estudo tem como objetivo principal caracterizar esp?cies de d?ptcros mnscoidcs de import?ncia m?dica-veterin?ria e forense, atrav?s da utiliza??o de duas t?cnicas modernas de identifica??o. O primeiro cap?tulo utiliza a microscopia eletr?nica de varredura que permite a visualiza??o e a determina??o de caracteres que possam ser utilizados na identifica??o das esp?cies. Foram estudados imaturos de tr?s esp?cies de d?pteros de duas fam?lias diferentes: Peckia (Eubaettcheria) callusar (Diptera: Sarcophagidae) (larvas e pup?rios), Lucilia cuprina (larvas e pup?rios) e Cachliamyia macellaria (ovos, larvas e pup?rios) (Diptera: Calliphoridae) atrav?s desta t?cnica. O tamanho das c?lulas do exoc?rion permitiu diferenciar entre C. macellaria e C. haminivarax, duas esp?cies causadoras de mi?ases. A aus?ncia de espinhos no espir?culo posterior das larvas de C. macellaria tamb?m a diferencia de C. haminivarax. As papilas do complexo do palpo maxilar em uma cavidade parecem ser espec?ficas do subg?nero Eubaettcheria. As aberturas respirat?rias do espir?culo anterior dispostas em fileiras irregulares s?o exclusivas da fam?lia Sarcophagidae. A presen?a de espinhos filamentosos no ?ltimo segmento larval ? caracter?stica espec?fica do g?nero Lucilia. No segundo cap?tulo, a t?cnica de harcade ? utilizada para a forma??o de um banco de dados contendo sequ?ncias g?nicas de esp?cies de import?ncia m?dica-veterin?ria e forense da fam?lia Calliphoridae. Esta t?cnica baseia-se no sequenciamento de uma por??o do gene mitocondrial citocromo oxidase I (cal). Foram analisadas nove esp?cies de d?pteros, coletadas em quatro regi?es do Brasil, em um total de 346 esp?cimes utilizados. Dois segmentos do genoma nuclear (fator de elonga??o 1 alfa e white) tamb?m foram sequenciados pela primeira vez para algumas esp?cies. A proposta de barcade foi bem sucedida em Hemilucilia segmentaria, Hemilucilia semidiaphana, Chlaraprocta idiaidea, Cachliamyia macellaria, Chrysamya megacephala e Chrysamya albiceps, onde a varia??o intraespec?fica foi menor do que 3%. Entretanto, em Lucilia eximia, Chrysamya putaria e Ch1ysamya rufifacies esta metodologia trouxe resultados incipientes. A varia??o intraespec?fica em Lucilia eximia foi 4,6%, sugerindo que o limiar proposto n?o deve ser aplicado em todos os d?pteros sem an?lise pr?via do grupo estudado. Chrysamya pularia ? uma esp?cie polifi!?tica comprovada tanto pelos genes nucleares quanto mitocondrial, al?m isso, uma parte das amostras forma um agrupamento com as amostras de C. albiceps e C. nijifacies. Assim, acrcditase que mais estudos precisam ser conduzidos com o objetivo de esclarecer melhor estas quest?es taxon?micas.
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M?todo gen?rico para estima??o e modelagem do erro RMS em dados de profundidade de sensores para vis?o 3DFernandez, Luis Enrique Ortiz 05 July 2017 (has links)
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Previous issue date: 2017-07-05 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES) / Na vis?o artificial usam-se v?rios dispositivos como o MS Kinect v1/v2, as c?meras
est?reo PG Bumblebee XB3 e a Stereolabs ZED, entre outros. Como todos s?o dispositivos
que estimam dados de profundidade, podem conter erros. Neste trabalho, apresenta-se
o projeto e implementa??o de um m?todo gen?rico para a estima??o do erro RMS em dados
de profundidade fornecidos por qualquer dispositivo, capaz de gerar dados do tipo
RGB-D, isto ?, uma imagem e um mapa de profundidade ao mesmo tempo. Para verifica??o
do m?todo foi constru?do um sistema embarcado baseado na placa NVIDIA Jetson
TK1 e tr?s sensores, as duas vers?es do MS Kinect e a c?mera est?reo ZED. No momento
da coleta de dados foram estabelecidos os modelos matem?ticos do erro RMS para cada
dispositivo e, ao final, foi feita uma an?lise da exatid?o de cada um. / In the artificial vision are used several devices like MS Kinect v1 / v2, the stereo
cameras PG Bumblebee XB3 and Stereolabs ZED, among others. Because they are all
devices that estimate depth data, they may contain errors. In this work, we present the
design and implementation of a generic method for estimating the RMS error in depth
data provided by any device, capable of generating data of type RGB-D, that is, an image
and a depth map Same time. To verify the method was built an embedded system based
on the NVIDIA Jetson TK1 and three sensors, the two versions of MS Kinect and the
ZED stereo camera. At the moment of the data collection, the mathematical models of
the RMS error were established for each device and, at the end, an analysis was made of
the accuracy of each one.
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Influ?ncia da utiliza??o de res?duo de cer?mica vermelha nas propriedades de argamassas mistasAra?jo, R?sia Amaral 06 November 2017 (has links)
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Previous issue date: 2017-11-06 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES) / A fabrica??o dos materiais de constru??o requer elevado disp?ndio de energia e extra??o de recursos naturais, o que implica na gera??o de impactos ambientais preocupantes, em fun??o da produ??o de res?duos gasosos e s?lidos, como tamb?m mudan?as desastrosas do meio ambiente. Nesse contexto, existe um inconveniente do uso de Cimento Portland, em raz?o do alto consumo energ?tico e emiss?o de di?xido de carbono provocado pela calcina??o da mat?ria prima. Outro material poluente ? o proveniente da ind?stria de cer?mica vermelha, o qual emite res?duos gasosos e ainda origina demasiado volume de res?duos s?lidos em virtude de falhas no processo produtivo. Por outro lado, na antiguidade, as argilas termicamente tratadas, inclusive na forma de tijolos cer?micos finamente mo?dos, foram amplamente utilizadas devido ?s reconhecidas propriedades hidr?ulicas que conferiam as argamassas de cal a?rea. Dessa forma, esse estudo pretende avaliar a influ?ncia do res?duo de cer?mica vermelha (RCV) oriundo de telhas nas propriedades de argamassas mistas, a fim de que possa ser dado um destino adequado a esse res?duo. O RCV ap?s cominu?do em part?culas menores que 0,036 mm, foi adicionado em substitui??o parcial ao cimento Portland no tra?o 1:1:6 (cimento: cal: areia) de argamassas mistas empregada em revestimentos de paredes e tetos. Inicialmente o res?duo foi caracterizado e sua atividade pozol?nica investigada por de meio ensaios mec?nicos, an?lises granulom?tricas, termogravim?tricas e microestruturais. O teor de substitui??o das argamassas foi variado em 0, 10, 20 e 30% e as respectivas propriedades no estado fresco (consist?ncia, densidade, teor de vazios e reten??o de ?gua) e no estado endurecido (absor??o de ?gua, densidade, resist?ncia ? tra??o na flex?o e ? compress?o, e m?dulo de elasticidade) foram avaliadas. Constatou-se que o RCV possui significativa quantidade de silicatos e aluminatos reativos, comprovadas pela expressiva atividade pozol?nica que foi identificada nas an?lises qu?micas e f?sicas e no ?ndice de desempenho mec?nico 11% superior ao de refer?ncia. J? na produ??o das argamassas de revestimento com RCV obteve-se uma melhoria na trabalhabilidade, comprovada pela otimiza??o das propriedades no estado fresco, obtidas entre os teores de substitui??o do cimento Portland. No estado endurecido, as propriedades f?sicas e mec?nicas das argamassas com RCV apresentaram-se equivalentes ? argamassa de refer?ncia para os tra?os com 20% e 30% de substitui??o e melhorias significantes para o tra?o com 10% de substitui??o do cimento Portland por RCV. Com isso, constata-se que o RCV apresenta caracter?sticas pozol?nicas que resulta na melhoria das propriedades da argamassa no estado fresco e endurecido, sendo o teor de 10% o mais indicado em virtude da otimiza??o das propriedades. / The manufacture of construction materials requires high energy expenditure and extraction of natural resources, which implies the generation of disturbing environmental impacts, due to the production of gaseous and solid residues, as well as disastrous changes of the environment. In this context, there is a drawback of the use of Portland cement, due to the high energy consumption and emission of carbon dioxide caused by the calcination of the raw material. Other polluting material is that of the red ceramic industry, which emits gaseous waste and still gives rise to too much solid waste due to failures in the production process. On the other hand, in ancient times, thermally treated clays, even in the form of finely ground ceramic bricks, were widely used because of the recognized hydraulic properties that conferred lime mortars. Thus, this study intends to evaluate the influence of the red ceramic residue (CVR) from tiles in the properties of mixed mortars, so that a suitable destination can be given to this residue. The RCV, after being comminuted in particles smaller than 0.036 mm, was added in partial replacement to Portland cement in the 1: 1: 6 (cement: lime: sand) of mixed mortars used in laying of walls and covering of walls and ceilings. Initially the residue was characterized and its pozzolanic activity was investigated by means of mechanical tests, grain size, thermogravimetric and microstructural analyzes. The substitution content of the mortars was varied in 0, 10, 20 and 30% and their properties in the dry state (consistency, density, voids content and water retention) and in the hardened state (water absorption, density, resistance to flexure and compression tensile strength, and modulus of elasticity) were evaluated. It was verified that the RCV has a significant amount of reactive silicates and aluminates, evidenced by the significant pozzolanic activity that was identified in the chemical and physical analyzes and in the mechanical performance index 11% higher than the reference value. In the production of mortars with RCV, an improvement in the workability demonstrated by the optimization of the fresh state properties obtained in the Portland cement substitution levels was obtained. In the hardened state the physical and mechanical properties of RCV mortars were equivalent to reference mortar for the traces with 20% and 30% substitution and significant improvements for the trait with 10% replacement of the Portland cement by RCV. With this, it is verified that the pozzolana obtained from the RCV is a potential Pozolana that results in the improvement of the properties of the mortar in the fresh and hardened state, being the content of 10% the most indicated due to the optimization of all the properties.
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Avalia??o dos processos de fratura em filmes finos atrav?s da simula??o de ensaios de indenta??o com penetradores esf?ricosChaves Filho, Ozias Ferreira 31 August 2017 (has links)
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Previous issue date: 2017-08-31 / Recentes trabalhos prop?em a utiliza??o dos ensaios de indenta??o (nanoindenta??o) como uma ferramenta capaz avaliar caracter?sticas (nanoindenta??o) como uma ferramenta capaz de avaliar caracter?sticas mec?nicas filmes finos, assim poss?veis falhas em sistemas que mec?nicas de filmes finos, assim como avaliar poss?veis falhas em sistemas que conjugam alta dureza com substratos met?licos a?o servi?o, conjugam filmes de alta dureza com substratos met?licos de a?o em servi?o, em solicita??es tribol?gicas. Entretanto, implementa??o da t?cnica solicita??es tribol?gicas. Entretanto, a implementa??o da t?cnica de indenta??o para avalia??o do comportamento destes e os seus resultados, para a avalia??o do comportamento destes sistemas e os seus resultados, continuam ocasionando d?vidas no meio cient?fico. Em fun??o destas incertezas continuam ocasionando d?vidas no meio cient?fico. Em fun??o destas incertezas na an?lise ensaio indenta??o, o uso num?rica na an?lise do ensaio de indenta??o, o uso de uma ferramenta num?rica capaz campos tens?es deforma??es durante ciclo de avaliar os campos de tens?es e de deforma??es durante o ciclo de identificando ?reas cr?ticas atrav?s mec?nica indenta??o, identificando poss?veis ?reas cr?ticas atrav?s da mec?nica da fratura, pode auxiliar interpreta??o mais segura deste ensaio. Este fratura, pode auxiliar em uma interpreta??o mais segura deste ensaio. Este trabalho tem proposta utilizar M?todo Elementos Finitos MEF) trabalho tem como proposta utilizar o M?todo dos Elementos Finitos (MEF) em conjunto Modelo Delamina??o Bimodularidade conjunto com o Modelo de Delamina??o e o Modelo de Bimodularidade para simular um filme CrAlN, possui simular ensaios de indenta??o em um filme de CrAlN, que possui uma alta aplicabilidade devido suas propriedades, analisar nuclea??o crescimento aplicabilidade devido a suas propriedades, e analisar a nuclea??o e crescimento trincas, podem ocorrer esses ensaios. Por fim, padr?es de trincas, que podem ocorrer durante esses ensaios. Por fim, os padr?es de surgimento trincas observados neste foram surgimento e crescimento de trincas observados neste trabalho foram comparados obtidos por outros modelos apresentados literatura comparados com os obtidos por outros modelos apresentados na literatura especializada. Tamb?m se concluiu concomitante dois modelosse especializada. Tamb?m se concluiu que o uso concomitante dos dois modelosse mostrou boa estudo nos mostrou uma boa ferramenta para o estudo de falhas nos ensaios de indenta??o finos. em filmes finos. / Recent publications propose the use of indentation testing (nanoindentation) as a tool to evaluate thin film?s mechanical properties, and (nanoindentation) as a tool to evaluate thin film?s mechanical properties, and possible failures in systems that unite high hardness film tribological evaluate possible failures in systems that unite high hardness film (tribological coating) metallic substrates steel, solicitations. However, coating) and metallic substrates of steel, in tribological solicitations. However, the implementation technique for evaluation these implementation of the indentation technique for the evaluation of these systems its results still brings on doubts scientific environment. Due and its results still brings on doubts to the scientific environment. Due to the around tests, numerical able analyze doubts around the indentation tests, the use of a numerical tool able to analyze stress displacement field during cycle, identifying the stress and displacement field during the indentation cycle, identifying possible critical areas using fracture mechanics may help give safer interpretation critical areas using the fracture mechanics may help to give a safer interpretation this test. This work?s proposal is Finite Elements Method FEM) of this test. This work?s proposal is to use the Finite Elements Method (FEM) combined with Delamination Model Cracking Strain simulate combined with Delamination Model and Cracking Strain Model to simulate cycles CrAlN film, has big applicability due indentation cycles on a CrAlN film, a film that has a big applicability due to its crack nucleation growth, which occur properties, and analyze crack nucleation and growth, which may occur during cycles. Finally, patterns growth presented work these cycles. Finally, the patterns of nucleation and growth presented in this work were compared others models specialized literature. Also were compared with others models presented on the specialized literature. Also concluded both together was good study concluded that the use of both models together was a good tool to the study of cracks films. cracks during indentation testing in thin films.
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Qualidade do sono e estado nutricional de pacientes reais cr?nicos no pr? e p?s-transplante renalSantos, Thais Teixeira dos 30 March 2016 (has links)
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Previous issue date: 2016-03-30 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES) / A doen?a renal cr?nica se caracteriza pela perda progressiva e irrevers?vel das fun??es renais a partir de uma doen?a ou ap?s uma insufici?ncia renal aguda, podendo causar problemas do sono e dist?rbios no metabolismo, absor??o e excre??o de nutrientes, prejudicando o estado nutricional. A m? qualidade do sono est? presente entre 80% dos pacientes renais e pode afetar diversos mecanismos relacionados ao funcionamento do nosso organismo, tais como a imunidade, as fun??es cognitivas e as manifesta??es afetivas. J? as altera??es nutricionais tamb?m s?o muito frequentes em pacientes com DRC e, entre as m?ltiplas causas dessa doen?a, destacam-se: a ingest?o deficiente de nutrientes, catabolismo, uremia, dist?rbios endocrinol?gicos e do equil?brio eletrol?tico. Devido ?s complica??es relacionadas com uremia, metabolismo, imunidade, maior susceptibilidade a doen?as inflamat?rias e cardiovasculares e ao risco aumentado de morte associados a uma qualidade de sono ruim e a um status nutricional inadequado, avaliaram-se as vari?veis qualidade do sono e qualidade nutricional de pacientes com doen?a renal cr?nica no pr? e p?s-transplante renal em um hospital universit?rio do munic?pio de Natal, Rio Grande do Norte. O estudo contou com 10 pacientes. No pr?-transplante renal houve associa??o dos sintomas de ansiedade com ins?nia, narcolepsia e s?ndrome das pernas inquietas (SPI); do uso de medicamentos para dormir com narcolepsia e SPI. No p?s-transplante renal, apneia esteve relacionada com a ansiedade e com o uso de medicamentos para dormir; a ins?nia e a narcolepsia com diabetes e hipoteiroidismo. O peso esteve relacionado com lat?ncia do sono, cochilos e qualidade de sono; o IMC e a circunfer?ncia da cintura com a lat?ncia do sono. Foi poss?vel concluir que, ap?s o transplante renal, houve melhora significativa na qualidade de sono, al?m de redu??o dos sintomas indicativos de dist?rbios do sono. O estado nutricional de modo geral tamb?m foi elevado assim como o aporte energ?tico-prot?ico. / Chronic kidney disease is characterized by progressive and irreversible loss of kidney function from an illness or after an acute renal failure, may cause sleep problems and impairing the nutritional status. The quality of bad sleep is present among 80% of renal patients and can affect immunity, cognitive functions and emotional manifestations. Already nutritional changes are related to poor nutrient intake, catabolism, uremia, endocrinological disorders and electrolyte balance. Because of the complications mentioned, we evaluated the variables sleep quality and nutritional status of patients with chronic kidney disease before and after renal transplantation in a university hospital of Natal, Rio Grande do Norte. The study included 10 patients and applied the sociodemographic questionnaire and for control over the variables, the Hospital Anxiety and Depression Scale. To evaluate the quality of sleep was used Sleep Quality Index of Pittsburgh, the Journal Sleep, Sleepiness Scale Epworth and H?biots Sleep Questionnaire; for sleep disorders Sleep Disorder Screening Questionnaire and the assessment of nutritional status Nutritional Subjective Global Assessment Modified, food surveys and laboratory tests. In pre-renal transplantation was associated symptoms of anxiety with insomnia, narcolepsy and restless legs syndrome (RLS); the use of sleep medications with narcolepsy and SPI. In post-renal transplant, apnea was associated with anxiety and the use of medications to sleep; insomnia and narcolepsy with diabetes and hipoteiroidismo. The weight was related to sleep latency, quality of sleep and naps; BMI and waist circumference with sleep latency. It was concluded that, after renal transplantation, there was significant improvement in quality of sleep, and reduction of the target symptoms of sleep disorders. The general nutritional status has also improved, as well as protein-energy contribution.
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Metaliza??o mec?nica com Ti de placas de Al2O3 utilizando m?quina ferramenta computadorizada para brasagem metal/cer?micaVieira, Jo?o Dantas Paiva 22 August 2015 (has links)
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Previous issue date: 2015-08-22 / Neste trabalho empregou-se a t?cnica de metaliza??o mec?nica para produzir um revestimento de metal ativo, no caso o tit?nio (Ti), no substrato cer?mico de alumina (Al2O3), a fim de favorecer o molhamento com ligas de adi??o convencionais. Utilizou-se um processo autom?tico com o emprego de uma m?quina ferramenta de controle num?rico computadorizado (CNC) sem a interven??o do operador. Posteriormente, a cer?mica metalizada foi brasada, com tubo met?lico de inox 304, por t?cnica indireta em forno de alto v?cuo, utilizando liga de adi??o convencional Ag-28Cu. A interface resultante foi caracterizada por t?cnica de an?lise micro estrutural em microsc?pio eletr?nico de varredura (MEV) acoplado com sistema de microan?lise qu?mica por energia dispersiva (EDS) e o desempenho mec?nico, por ensaio de cisalhamento, realizado em uma m?quina universal de ensaios mec?nicos, que apresentou baixos valores da tens?o de cisalhamento. A metaliza??o com tit?nio mostrou resultado satisfat?rio com pode ser observado pelas an?lises microsc?picas, enquanto a brasagem apresentou diferen?as significativas, a menor, nos resultados de resist?ncia das amostras analisadas, quando comparadas a outros trabalhos, na mesma ?rea. / In this work employed the mechanical metallization technique to produce a thin film of
titanium in the ceramic substrate of alumina (Al2O3), in order to favor wetting with
conventional adding alloys. Was used an automated process with employment a
machine tool computer numerical control (CNC) without operator intervention.
Subsequently, the metallized ceramic was brazed with metallic stainless steel tube 304,
by indirect technique in high-vacuum oven, using conventional alloying addition Ag-
28Cu. The resulting interface was characterized by technique of micro structural
analysis using scanning electron microscopy (SEM) coupled with energy dispersive
spectroscopy (EDS) for chemical microanalysis and mechanical performance, shear test,
carried out on a universal testing machine. The titanium metallization film was observed
by electron microscopy showing an interface with good interaction between the
elements of the materials involved, and the thickness of the layer of titanium fairly
regular, consistent with results in the same work area. While brazing interface presented
some defects, mainly due to the furnace atmosphere and vacuum pressure, which has
not reached the specified value, identified in other studies, which influenced, to some
extent, the mechanical results.
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Caracteriza??o qualiquantitativa dos recursos h?dricos e da din?mica do carbono de turfeiras das cabeceiras do Rio Ara?ua?Bispo, Di?go Faustolo Alves 23 August 2013 (has links)
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Previous issue date: 2013 / As turfeiras s?o importantes reguladores dos fluxos de ?gua e de elementos, principalmente do carbono, entre os compartimentos terrestres e aqu?ticos. O objetivo deste trabalho foi caracterizar qualiquantitativamente os Organossolos e os recursos h?dricos das turfeiras das cabeceiras do Rio Ara?ua? quanto ? disponibilidade h?drica e a din?mica do carbono no sistema solo-?gua. Coletou-se oito testemunhos representantes de quatro perfis de solo do Campo Limpo ?mido e Floresta Estacional Semidecidual de duas turfeiras nas cabeceiras de afluentes do Rio Ara?ua? (C?rrego Cachoeira dos Borges e Rio Preto), descritos e caracterizados f?sica, qu?mica, elementar e morfologicamente. Em tr?s pontos do curso d??gua de cada afluente e duas ?pocas (chuvosa e seca) foram coletadas amostras de ?gua e analisados os seus atributos f?sicos e qu?micos. Procedeu-se o mapeamento das turfeiras e o c?lculo dos volumes e fluxos de ?gua e de carbono. Empregou-se an?lise de vari?ncia para atestar o efeito das fitofisionomias, profundidades de amostragem e das intera??es destes fatores sobre as vari?veis do solo. Para os atributos da ?gua atestaram-se efeitos dos locais (afluentes), ?pocas de amostragem e das intera??es entre estes fatores. Boa parte dos atributos caracterizadores da mat?ria org?nica e a composi??o elementar do solo apresentaram diferen?as significativas entre os locais, fitofisionomias e profundidades de amostragem e variaram em fun??o da composi??o e grau de evolu??o do material org?nico. A maioria dos atributos f?sico-qu?micos das ?guas n?o diferenciou entre os locais e nem entre as ?pocas, mas foram influenciados pelos atributos dos Organossolos de onde se originam. A turfeira do Rio Preto estoca 4.299,39 t de C (206,70 t ha-1) e 227.258,15 m3 de ?gua (10.925,87 m3 ha-1) e a turfeira do C?rrego Cachoeira dos Borges estoca 14.781,09 t de C (184,10 t ha-1) e 745.950,30 m3 de ?gua (9.290,70 m3 ha-1). A vaz?o do Rio Preto foi de 0,023 m3 s-1 e do C?rrego Cachoeira dos Borges foi de 0,067 m3 s-1 no per?odo chuvoso. No per?odo seco estes cursos d??gua apresentaram vaz?o m?nima constante, demonstrando a capacidade das turfeiras de suas cabeceiras de perenizar a vaz?o. Estimou-se o lan?amento de uma carga m?dia de 360,84 t ano-1 de N e 6.812,73 t ano-1 de C e de 917,32 t ano-1 de N e 33.516,16 t ano-1 de C, respectivamente para o Rio Preto e C?rrego Cachoeira dos Borges. As turfeiras das cabeceiras dos afluentes do Rio Ara?ua? influenciam significativamente na vaz?o e na qualidade de suas ?guas, sendo urgente a necessidade de preserva??o destes pedoambientes. / Disserta??o (Mestrado) ? Programa de P?s-Gradua??o em Produ??o Vegetal, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2013. / ABSTRACT The peatlands are important regulators of water flows and elements between terrestrial and aquatic compartments, especially of the carbon. The objective of this study was to characterize qualitatively and quantitatively the Histosols and water resources of headwater from peatlands of the Rio Ara?ua? as to hydric availability and carbon dynamics in the soil-water system. Been collected eight testimonies representatives from four soil profiles of moist meadow and semi-deciduous seasonal forest in two peatlands in the headwaters of affluents of the Rio Ara?ua? (C?rrego Cachoeira dos Borges e Rio Preto), described and characterized physics, chemistry, elementary and morphologically. In three points of each watercourse affluent and two seasons (wet and dry) water samples were collected and analyzed their physical and chemical attributes. Been done the mapping of peatlands and the calculation of volumes and flows of water and carbon. It was used analysis of variance to attested effect of vegetation types, sampling depths and the interactions of these factors over soil variables. For the attributes of water attested effects of local (affluents), sampling periods and the interactions between these factors. Much of the attributes that characterize the organic matter and elemental composition of the soil, showed significant differences between the sites, vegetation types and depths of sampling and varied according to the composition and degree of evolution of the organic material. Most physical and chemical attributes of the water did not differ between the sites and between sampling periods, but were influenced by the attributes of the Histosols of where they originate. The peatland from Rio Preto stocks 4,299.39 tons of C (206.70 tons ha-1) and 227,258.15 m3 (10,925.87 m3 ha-1) of water and peatland from the C?rrego Cachoeira dos Borges stocks 14,781.09 tons of C (184.10 tons ha-1) and 745.950,30 m3 (9.290,70 m3 ha-1) of water. The flow of water of the Rio Preto was 0.023 m3 s-1 and of the C?rrego Cachoeira dos Borges was 0.067 m3 s-1 in the rainy season. These watercourses showed constant minimum flow in the dry season, demonstrating the capacity of peatlands its headwaters to maintain water flow. It has been estimated the launch of a load average of 360.84 tons year-1 of N and 6812.73 tons year-1 of C and of 917.32 tons year-1 of N and 33516.16 tons year-1 of C respectively for the Rio Preto and C?rrego Cachoeira dos Borges. The peatlands from the headwaters of the affluents of the Rio Ara?ua? have a significant influence the flow and quality of its waters, and the urgent need to preservation these pedological environments.
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