Análise dos dez Estudos para violão de Radamés Gnattali com ênfase no aspecto harmônico, utilizando as ferramentas analíticas desenvolvidas no século XX para tratar de procedimentos harmônicos não-tradicionais. Tem como objetivo compreender as estruturas sonoras, salientando questões como movimento harmônico, prolongamento harmônico e melódico, sonoridades octatônicas e de tons inteiros e forma. / Analysis of the ten Studies for guitar by Radamés Gnattali, emphasizing the harmonic aspect, using the analytical tools developed in the 20th century to treat non-traditional harmonic procedures. The objective is to understand the sound structures, highlighting issues such as harmonic movement, harmonic and melodic prolongation, octatonic and whole tone sonorities, and form.

Czech Republic, like other European developed countries, has to deal with impacts of population ageing. The number of older people in society grows therefore the drain on workers in productive age is rising. Population ageing causes problems within current setting of the Czech pension system, especially in long-term sustainability of public finance. Hence added involvement of elderly people into working process becomes necessary. The goal of this Masters thesis is to analyse the situation of older workers on Czech labour market between 2005 and 2015 and to find some possible solutions that would increase the employment rate of people before and in retirement age. There are four chapters in the theoretical part that are dealing with population ageing, labour market, specificities of employing older workers and tools used to increase the employment rate. The practical part is focused on demographic situation in the Czech Republic and especially on analysis of the situation of older workers on the Czech labour market in comparison to countries of the European Union. Analysis that was carried out confirms that the overall employment rate of older workers in the Czech Republic is on a good level however there are some areas that need to be improved. For example, option of using part time working contracts is underused as well as the motivation of elderly people to stay economically active. In the last chapter there are possible solutions suggested. These recommendations could strengthen motivation of older workers to stay on labour market and in the same time should motivate employers to employ these workers.

Introduction: Congenital short femur, or proximal femoral focal deficiency (PFFD), is a rare complex deformity of the lower extremity with femoral dominance. The clinical findings cover wide range of variety, from femoral absence till inconspicuous shortening of the femur. Aim of the study: 1. Molecular analysis of pseudoarthrosis tissue in congenital short femur with focusing on osteogenic and angiogenic gene expression in comparison with physiological bone. The differences in gene expression were expected. 2. Retrospective analysis of femoral healing after prolongation calculating the severity of affection, age, distance of elongation and complication. The extended healing according to severity type and age was expected compared to control group. Material and methods: The RNA from piece of one was isolated and transcription profile of possible 113 genes of osteogenesis and angiogenesis was detected by biochip technology (SuperArray Bioscience Corporation). 10 samples analyses were performed (7 of PFFD, 3 controls). The data of 57 PFFD patients indicated for elongation of the femur with the types Pappas III, IV, VII, VIII and IX and 12 patients in control group were evaluated retrospectively and statistically by GLS method. Results: The expected differences in gene expression in PFFD tissue...

Network Calculus views a network system as a queuing framework and provides a series of mathematical functions for finding an upper bound of an end-to-end delay. It is crucial for the design of networks and applications with a hard delay guarantee, such as the emerging Time Sensitive Network. Even though several approaches in Network Calculus can be used directly to find bounds on the worst-case delay, these bounds are usually not tight, and making them tight is a hard problem due to the extremely intensive computing requirements. This problem has also been proven as NP-Hard. One newly introduced solution to tighten the delay bound is the so-called Flow Prolongation. It extends the paths of cross flows to new sink servers, which naturally increases the worst-case delay, but might at the same time decrease the delay bound. The most straightforward and the most rigorous solution to find the optimal Flow Prolongation combinations is by doing exhaustive searches. However, this approach is not scalable with the network size. Thus, a machine learning model, Graph Neural Network (GNN), has been introduced for the prediction of the optimal Flow Prolongation combinations, mitigating the scalability issue. However, early research also found out that machine learning models consistently misclassify adversarial examples. In this thesis, Fast Gradient Sign Method (FGSM) is used to benchmark how adversarial attacks will influence the delay bound achieved by the Flow Prolongation method. It is performed by slightly modifying the input network features based on their gradients. To achieve this, we first learned the usage of NetCal DNC, an Free and Open Source Software, to calculate the Pay Multiplexing Only Once (PMOO), one of the Network Calculus methods for the delay bound calculation. Then we reproduced the GNN model based on PMOO, and achieved an accuracy of 65%. Finally, the FGSM is implemented on a newly created dataset with a large number of servers and flows inside. Our results demonstrate that with at most 14% changes on the network features input, the accuracy of GNN drastically decreases to an average 9.45%, and some prominent examples are found whose delay bounds are largely loosened by the GNN Flow Prolongation prediction after the FGSM attack. / Nätverkskalkylen behandlar ett nätverkssystem som ett system av köer och tillhandahåller ett antal matematiska funktioner som används för att hitta en övre gräns för end-to-end förseningar. Det är mycket viktigt för designen av nätverk och applikationer med strikta begränsningar för förseningar, så som det framväxande Time Sensitive Network. Även om ett flertal tillvägagångssätt i nätverkskalkylen kan användas direkt för att finna gränsen för förseningar i det värsta fallet så är dessa vanligtvis inte snäva. Att göra gränserna snäva är svårt då det är ett NP-svårt problem som kräver extremt mycket beräkningar. En lösning för att strama åt förseningsgränserna som nyligen introducerats kallas Flow Prolongation. Den utökar vägarna av korsflöden till nya sink servrar, vilket naturligt ökar förseningen i värsta fallet, men kan eventuellt också sänka förseningsgränsen. Den enklaste och mest rigorösa lösningen för att hitta de optimala Flow Prolongation kombinationerna är att göra uttömmande sökningar. Detta tillvägagångssätt är dock inte skalbart för stora nätverk. Därför har en maskininlärningsmodell, ett Graph Neural Network (GNN), introducerats för att förutspå de optimala Flow Prolongation kombinationerna och samtidigt mildra problemen med skalbarhet. Dock så visar de tidiga fynden att maskininlärningsmodeller ofta felaktigt klassificerar motstridiga exempel. I detta projekt används Fast Gradient Sign Method (FGSM) för att undersöka hur motståndarattacker kan påverka förseningsgränsen som hittas med hjälp av Flow Prolongation metoden. Detta görs genom att modifiera indata-nätverksfunktionerna en aning baserat på dess gradienter. För att uppnå detta lärde vi oss först att använda NetCal DNC, en mjukvara som är gratis och Open Source, för att kunna beräkna Pay Multiplexinng Only Once (PMOO), en metod inom nätverkskalkylen för att beräkna förseningsgränser. Sedan reproducerade GNN modellen baserat på PMOO, och uppnådde en träffsäkerhet på 65%. Slutligen implementerades FGSM på ett nytt dataset med ett stort antal servrar och flöden. Våra resultat visar att förändringar på upp till 14% på indata-nätverksfunktionerna resulterar i att träffsäkerheten hos GNN minskar drastiskt till ett genomsnitt på 9.45%. Vissa exempel identifierades där förseningsgränsen utvidgas kraftfullt i GNN Flow Prolongation förutsägelsen efter FGSM attacken.

Les médicaments qui provoquent un allongement de la repolarisation cardiaque, mesuré sur l’électrocardiogramme (ECG) par la prolongation de l’intervalle QT, ont été associés à une augmentation du risque pro-arythmique, et plus particulièrement à la survenue de Torsades de pointes, une tachycardie ventriculaire polymorphe potentiellement mortelle. Les méthodes d'analyse du QT conventionnelles se restreignent à l’extraction de quelques complexes ECG. Cette pratique se traduit par de nombreuses limitations. L’inclusion de tous les battements enregistrés sur 24h et mesurés par des méthodes automatiques de mesure ECG a le potentiel de résoudre ces inconvénients. Ce travail de thèse a démontré que les méthodes de mesure ECG automatisées et les analyses continues peuvent supplanter les méthodes conventionnelles pour l'analyse de la prolongation du QT lors des essais cliniques. Des recommandations ont été établis afin de permettre une utilisation optimale des méthodes d'analyse ECG continues. / Drugs which induce a delay in cardiac repolarization measured as QT interval prolongation on the electrocardiogram (ECG) have been associated with a potential to increase the risk of arrhythmias, especially Torsades de pointes (TdP), a potentially lethal polymorphic ventricular tachycardia. The analyses performed using conventional methods are restricted to the extraction of a few ECG complexes. This practice is associated with several limitations. In contrast, the inclusion of all beats measured by computerized methods from continuous 24 h recordings could resolve all of these deficiencies. The current work demonstrated that automated ECG measurement methods employing continuous analysis can supplant conventional methods for the evaluation of QT prolongation in clinical studies. Recommendations have been established to provide an optimal use of continuous ECG analysis.

Gegeben sei ein lineares Gleichungssystem $Au = f$ mit Koeffizientenmatrix $A$, welche eine spezielle block-tridiagonale Struktur besitzt. Solche lineare Gleichungssysteme entstehen bei der Diskretisierung dreidimensionaler elliptischer Randwertprobleme mit 7- oder 27-Punkte-Stern. In geophysikalischen Anwedungen, insbesondere bei Aufgaben aus der Geoelektrik, haben die Randwertprobleme unstetige Koeffizienten und sind meistens auf nicht-uniformen Gittern diskretisiert. Klassische geometrische Mehrgitterverfahren konvergieren um so langsamer, je stärker die Koeffizientensprünge ausfallen. Außerdem kann die Konvergenz durch die Variation der Gitterabstände beeinträchtigt werden. Zur Lösung wird ein matrix-abhängiges Mehrgitterverfahren vorgestellt. Als Glätter wird eine unvollständige Block LU-Zerlegung verwendet. Die Gittertransferoperationen werden anhand der Einträge der Matrix $A$ ermittelt. Das resultierende Verfahren erweist sich als sehr robust, insbesondere wenn es als Vorkonditionierung für das Verfahren der konjugierten Gradienten eingesetzt wird.

Les médicaments qui provoquent un allongement de la repolarisation cardiaque, mesuré sur l'électrocardiogramme (ECG) par la prolongation de l'intervalle QT, ont été associés à une augmentation du risque pro-arythmique, et plus particulièrement à la survenue de Torsades de pointes, une tachycardie ventriculaire polymorphe potentiellement mortelle. Les méthodes d'analyse du QT conventionnelles se restreignent à l'extraction de quelques complexes ECG. Cette pratique se traduit par de nombreuses limitations. L'inclusion de tous les battements enregistrés sur 24h et mesurés par des méthodes automatiques de mesure ECG a le potentiel de résoudre ces inconvénients. Ce travail de thèse a démontré que les méthodes de mesure ECG automatisées et les analyses continues peuvent supplanter les méthodes conventionnelles pour l'analyse de la prolongation du QT lors des essais cliniques. Des recommandations ont été établis afin de permettre une utilisation optimale des méthodes d'analyse ECG continues.

This thesis deals with the theory of geometric control of the trident robot. The thesis describes the basic concepts of differential geometry and control theory, which are subsequently used for describing various mechanisms. Finally, the thesis proposes the management using inferred results.

The thesis evaluates the work and the meaning of the Czech-German Future Fund as one of the key players in the role of deepening and hardening the Czech-German relations. The institution is characterized by the concepts of the soft power and of the reconciliation. The sources of the soft power are directly connected with the concept of the reconciliation. Namely it works with the sources of the foreign policy, the culture and the political values. These are connected with the prolongation of the Fund, Czech-German Journalist Prices and the announcement of the Topic of the Year. The Czech-German Fund was established on the basis of the Czech-German Declaration and its time of existence was initially restricted to 10 years. However, since its establishment in the year 1997 its existence has been extended twice already. The main aim of the work is to characterize the Czech- German Future Fund as a unique organisation of its kind on the background of the evolution of the Czech-German relationship. Besides the main concept of the soft power the work uses the concept of the reconciliation. Especially the four phases of the institution evaluation after the model of Lily Gardner Feldman: circumscription, growth, consolidation, revaluation. In the work, the both concepts are connected and examined closely...

Gegeben sei ein lineares Gleichungssystem $Au = f$ mit Koeffizientenmatrix $A$, welche eine spezielle block-tridiagonale Struktur besitzt. Solche lineare Gleichungssysteme entstehen bei der Diskretisierung dreidimensionaler elliptischer Randwertprobleme mit 7- oder 27-Punkte-Stern. In geophysikalischen Anwedungen, insbesondere bei Aufgaben aus der Geoelektrik, haben die Randwertprobleme unstetige Koeffizienten und sind meistens auf nicht-uniformen Gittern diskretisiert. Klassische geometrische Mehrgitterverfahren konvergieren um so langsamer, je stärker die Koeffizientensprünge ausfallen. Außerdem kann die Konvergenz durch die Variation der Gitterabstände beeinträchtigt werden. Zur Lösung wird ein matrix-abhängiges Mehrgitterverfahren vorgestellt. Als Glätter wird eine unvollständige Block LU-Zerlegung verwendet. Die Gittertransferoperationen werden anhand der Einträge der Matrix $A$ ermittelt. Das resultierende Verfahren erweist sich als sehr robust, insbesondere wenn es als Vorkonditionierung für das Verfahren der konjugierten Gradienten eingesetzt wird.