Orientador: Paulo Henrique Ferreira Caria / Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba / Made available in DSpace on 2018-08-22T04:10:47Z (GMT). No. of bitstreams: 1 PaulaJunior_FaustoAntoniode_M.pdf: 1772766 bytes, checksum: 78c522c3972255a7ea165ea489f7c456 (MD5) Previous issue date: 2013 / Resumo: O diagnóstico diferencial entre indivíduos portadores de otalgia pode ser um grande desafio clínico devido à sobreposição de sinais e sintomas e principalmente quando não há uma doença diagnosticada pela otoscopia, portanto, o objetivo desta pesquisa foi fornecer elementos diagnósticos que permitam aprimorar o diagnóstico diferencial das otalgias primárias e secundárias à disfunção temporomandibular (DTM). Foram selecionados 112 voluntários (90 mulheres e 22 homens) com idade igual ou acima de 18 anos (idade média: 45,39 ± 17,2), que compareceram entre janeiro e setembro de 2012, ao ambulatório de Otorrinolaringologia do Hospital e Maternidade Santa Casa de Limeira com queixa de otalgia. Todos os voluntários foram examinados de acordo com uma ficha clínica elaborada de acordo com 3 guidelines: 1) Academia Americana de Otorrinolaringologia, 2) Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico Facial e 3) Eixo I do Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD). Os exames possibilitaram classificar os voluntários em portadores de Otalgia Primária (OP), Otalgia Secundária à Disfunção Termporomandibular (OSDTM) e Otalgia Não Relacionada à Disfunção Temporomandibular (OSNDTM) e às DTMs em: grupo I (desordem muscular), grupo II (deslocamento de disco) e grupo III (artralgia, osteoartrite e osteoartrose). Após o diagnóstico, os voluntários foram comparados em relação às características da dor, frequência de dor à palpação muscular, ruídos articulares e presença de sintomas otológicos. Utilizou-se o teste Qui-quadrado para comparar as características da otalgia em pacientes com OSDTM e OP e o teste de Mann- Whitney para avaliar a associação dos sintomas otológicos, palpação muscular e ruídos articulares nos voluntários com otalgia secundária e primária. Estabeleceu se 5% como nível de significância para todos os testes. Os resultados mostraram que 92 (82,1%) voluntários foram diagnosticados com OSDTM, 15 (13,4%) com OP e cinco (4,5%) com OSNDTM. No tocante aos diagnósticos orientados pelo RDC/TMD obtivemos artralgia e dor miofascial com as maiores prevalências, respectivamente, 71 (77,2%) e 54 (58,7%). Os voluntários com OSDTM apresentaram otalgia prolongada (anos): 39 (42,4%), recorrente: 66 (71,7%), do tipo puntiforme: 49 (53,3%) e irradiada para duas ou mais regiões: 62 (67,4%). Em relação aos voluntários classificados como OP, prevaleceu à dor com menor tempo de duração (dias) ao diagnóstico: 10 (66,7%), constante: 13 (86,6%), do tipo pulsátil em seis (40%) dos casos e pontada em outros seis (40%), e irradiada para apenas uma região: 12 (80%). Observou-se ainda, que os voluntários com OSDTM, em relação aos pacientes com OP, apresentaram significativamente maior frequência de dor à palpação da musculatura avaliada e de ruídos articulares. No tocante aos sintomas otológicos, tontura e prurido auricular prevaleceram nos voluntários com OSDTM e nos voluntários com OP foram mais frequente os sintomas de plenitude auricular e zumbido. Concluiu-se que os voluntários com otalgia secundária à DTM e otalgia primária apresentam um perfil de dor com diferenças significativas em relação ao tempo de dor, frequência, irradiação e caráter. Além disso, os voluntários portadores de OSDTM apresentam maior prevalência de dor à palpação da musculatura indicada pelo RDC/TMD e maior frequência de ruídos articulares. Portanto, diante de um paciente com otalgia, os sintomas (características da dor) e sinais (palpação muscular e ruídos articulares) podem indicar o provável diagnóstico / Abstract: Differential diagnosis among individuals with otalgia can be a major clinical challenge due to overlapping symptoms, and especially without an elemental disease on otoscopy, therefore, the aim of this research was to provide diagnostic elements to improve the differential diagnosis of primary otalgias and secondary otalgias to temporomandibular disorder (TMD). It was selected 112 volunteers (90 women and 22 men) with aged greater than or igual to 18 years old (average age 45.39±17.2 years old), who came between January and September 2012, at the Otorhinolaryngology Department of the Santa Casa Hospital in Limeira, complaining otalgia. All volunteers were examined according to a clinical record prepared of according to 3 guidelines: 1º) American Academy of Otolaryngology, 2º) Brazilian Association of Otolaryngology and Facial Surgery and 3º) Axis 1 of the Research Diagnostic Criteria for Temporomandibular Disorders. The tests allowed to classify volunteers with primary otalgia (PO), secondary otalgia to termporomandibular disorder (SOTMD) and otalgia not related to temporomandibular disorder (SONTMD) and the TMDs in: group I (muscle disorder) group II (disc displacement) and group III (arthralgia, osteoarthritis and osteoarthoroses). After diagnosis, the volunteers were compared to the characteristics of pain, frequency of pain on muscle palpation, joint sounds and otologic symptoms. The chi-square test was used to compare the characteristics of otalgia in volunteers with SOTMD and PO. It was used the Mann-Whitney test to evaluate the association of otologic symptoms, muscle palpation and joint souds in volunteers with primary and secondary otalgia. It was established as 5% the significance level for all tests. The results showed that 92 (82.1%) volunteers were diagnosed with SOTMD, 15 (13.4%) with PO and five (4.5%) with SONTMD. Regarding to the diagnoses guided by RDC/TMD the arthralgia and miofascial pain showed the highest prevalence's, respectively, 71 (77.2%) e 54 (58.7%). The volunteers with SOTMD presented with a longer duration of otalgia: 39 (42.4%), reoccurring: 66 (71,7%), having a sensation like an input spear 49(53.3%) and spreading over more than a single region: 62 (67,4%). The individuals classified as PO had greater frequency of acute pain, lasting for days: 10 (66.7%), constant: 13 (86.6%) and pulsating in 40% of the cases, stabbing in another 40%, and radiating over one region: 12 (80%). It was also observed that the volunteers with SOTMD, compared to volunteers with PO, have significantly higher frequency of pain on palpation in most muscles examined and joint sounds. Regarding to otologic symptoms, dizziness and ear pruritus were more common in volunteers classified as having SOTMD, while in the PO volunteers the symptoms of stuffy sensation and tinnitus were more frequent. It was concluded that subjects with secondary otalgia to TMD and primary otalgia reveals a profile of pain with significant differences in relation to duration, frequency, irradiation and character. Moreover, the SOTMD volunteers present a higher prevalence of pain upon muscle palpation and joint sounds. Therefore, facing a patient with otalgia, the symptoms (pain characteristics) and signs (muscle palpation and joint sounds) may indicate a likely diagnosis / Mestrado / Anatomia / Mestre em Biologia Buco-Dental

The general purpose of this study was to both evaluate the effectiveness of filial therapy and describe the filial treatment process with parents court-referred for maltreatment. In filial therapy, parents learn basic play therapy skills in a group format that they implement in weekly home play sessions. They then generalize these skills into their parenting. Three research questions guided the quantitative portion of this investigation: (1) Is filial therapy effective at reducing the child abuse potential of parents court-referred for maltreatment? (2) Is filial therapy effective at reducing parenting stress for parents court-referred for maltreatment? (3) Is filial therapy effective at strengthening the parent-child relationship for parents court-referred for maltreatment? Qualitative data about parents' experience in the filial group was also collected and addressed the following questions: (1) How does the filial therapy process affect participants? (2) How does the filial therapy process affect treatment outcome? (3) What changes, in addition to those measured quantitatively, are reported by parents. The experimental group participants (n=7) received 8 weeks of filial therapy (modified from Landreth's (1991) 10-week model) in 1-1/2 hour weekly sessions. The control group (n=5) received a local agency's standard treatment. Parents completed two instruments, the Parenting Stress Index (PSI) and the Child Abuse Potential Inventory (CAP). Analyses of covariance indicated that parents significantly reduced there parenting stress and strengthened the parent-child relationship. Although parents did not significantly reduce their child abuse potential in this study, those results were based on an incomplete analysis. Most of the pre-test CAP scores for parents in the experimental group (6 of 7) were invalid as a result of excessive "faking good responses." As a result, only post-test scores could be compared between the experimental and control groups. The qualitative data revealed that parents made important changes during the filial therapy process. / Ph. D.

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Magistro darbe analizuojamas UAB ,,Mažeikių šilumos tinklai’’ (toliau tekste – įmonė) veiklos efektyvumas 2003 – 2007 metais, pateikiamas 2008 – 2010 metų perspektyvų vertinimas, įgalinantis priimti praktinį sprendimą gerinant įmonės finansinę padėtį (gamtinių dujų panaudojimas) bei užtikrinant veiklos stabilumą (įskaitant vartotojų nepertraukiamą aprūpinimą šilumos energija) – kogeneracinės jėgainės įdiegimą. Darbe pateikiamos įmonės ekonominių rodiklių (finansinio stabilumo, likvidumo, komercinės veiklos aktyvumo, rentabilumo ir kt.) reikšmės 2003 – 2007 metais ir laukiami rodikliai 2008 – 2010 metais. Patvirtinama autorių suformuluota mokslinio tyrimo hipotezė, kad kuro kainų didėjimo įtaka gali būti kompensuojama organizacinėmis – techninėmis priemonėmis, įgalinančiomis stabilizuoti sąnaudų ir tuo pačiu – šilumos energijos pardavimo kainos augimą. Pateikiami konkretūs pasiūlymai ir ekonominiai skaičiavimai. Metodika, kuria galės naudotis visos šilumos energiją gaminančios įmonės savo veiklos efektyvumo ekonominiam vertinimui, pateikta lentelės forma (MS Excel programos pagrindu), sudarys prielaidas formuoti finansinius koeficientus bei kitą informaciją apie įmonės veiklos efektyvumą. Lentelė pridedama CD laikmenoje. / Master thesis analyzes UAB (PLLC) “Mažeikių šilumos tinklai” (further referred to as company) performance efficiency during the period of 2003 – 2007 year, presents an outlook assessment for the 2008 – 2010 period, enabling to make practical decisions in improving financial status of the company (utilization of natural rare gas) as well as ensuring performance stability (including continuous provision of heat energy to consumers) – instillation of cogeneration plants. The Paper presents the values of economic indicators (financial stability, liquidity, business activity, profitability, etc.) for the period of 2003 – 2007 year and the expected indicators for the 2008 – 2010 period. The research hypothesis, formulated by the authors - that the impact of the increasing fuel costs may be compensated by organizational – technical means, enabling to stabilize the increase of expenditure and, concurrently, selling price of heat energy - has been verified. Specific propositions as well as economic calculations are presented. The methodology, that could be used by all companies, producing heat energy, for the economic assessment of their performance efficiency, is presented in the form of a table (on the grounds of MS Excel program), into which a company should enter financial statement data and other information and the program shall deliver the financial ratios and other information concerning performance efficiency of the company. The table is enclosed in the form of a CD medium... [to full text]

This dissertation examines the mental health presentations of clinic-referred children in state ordered out-of-home care and compares these to the presentations of clinic-referred children from the general population. The results of this study will inform the design of a more comprehensive research project assessing the differences between the psychopathology of clinic-referred children in out-of-home care and children from the general population. The overall goal is for researchers and clinicians to be able to better understand the underlying determinisms of the psychopathology of children in out-of-home care. Three samples were used for the between-group comparisons. The Children in Care Study (CICS) sample consists of 213 clinic-referred children in out-of-home care between the ages of four and eleven years. Firstly, this group was compared to 800 clinic-referred children, between six and eleven years, from the general population. For this analysis, the CICS sample was adjusted to match this group’s age range. Secondly, the entire CICS sample was compared to 1201 clinic-referred children, between the ages of four and eleven, from the general population. Mental health presentations were measured using the Child Behaviour Checklist (CBCL). A within-subject comparison was conducted comparing the CICS sample’s CBCL DSM-oriented scores to the children’s caregiver-reported diagnosis. Results indicated that clinic-referred children in care presented with significantly fewer internalising symptoms than clinic-referred children from the general population. Clinic-referred children in care displayed greater correlations among their CBCL subscale scores than other clinic-referred children, which may suggest greater symptom complexity. Additionally, there appeared to be poor concordance between caregiver-reported psychiatric diagnoses and CBCL DSM-oriented scores for clinic-referred children in out-of-home care. Overall, the mental health presentations measured by the CBCL indicated that the differences between the two populations were relatively small in terms of their severity. However, clinic-referred children in care presented with less severe internalising problems than other clinic-referred children. Further research is needed to explore the issues underlying diagnostic dis-concordance and the complexity of the mental health presentations of children in state ordered care.

Referred pain is frequently associated with misdiagnosis and unnecessary therapy directed to the pain location instead of its origin. When craniofacial pain is the sole symptom of myocardial ischemia, failure to recognize its cardiac source can endanger the patient. In particular, patients with acute myocardial infarction (AMI) who do not experience chest pain run a very high risk of misdiagnosis and death. Pain that is limited to the craniofacial region during myocardial ischemia has so far been described only in case reports and its overall prevalence is unknown. Experimental research in animals suggests a vagal involvement in the pathological mechanisms of cardiac pain referred to the face. The aim of this study was to gain knowledge about the prevalence, clinical characteristics and possible mechanisms of craniofacial pain of cardiac origin, in order to improve the clinician’s ability to make a correct diagnosis. It was hypothesized that the quality of craniofacial pain from cardiac versus dental origin would differ, implying a high diagnostic validity. It was also hypothesized that craniofacial pain can be the sole symptom of a prodromal (pre-infarction) angina episode and that this pain location would be especially associated with cardiac ischemia in the areas more densely innervated by vagal afferent fibres. The study group was comprised of consecutive patients who experienced craniofacial pain of a verified cardiac (n=326) or dental (n=359) origin. Demographic details on age, gender and pain characteristics (location, quality and intensity) were assessed in both groups. Cardiovascular risk factors, cardiac diagnosis and ECG signs of ischemia were also assessed in the cardiac pain group. Ethics approval and informed consent for each patient was obtained. Craniofacial pain was found to be the sole symptom of myocardial ischemia in 6% of patients and was the sole symptom of an AMI in 4% of patients; this craniofacial pain was more prevalent in women (p=0.031). In those patients without chest pain, it was the most frequent pain location and was the only symptom of prodromal angina in 5% of AMI patients. The craniofacial pain included the throat, the jaws, the temporomandibular joints/ears and the teeth, mainly bilaterally. The pain quality descriptors “pressure” and “burning” were statistically associated with pain of cardiac origin, while “throbbing” and “aching” were associated with an odontogenic cause (p<0.001). In myocardial ischemia patients, the occurrence of craniofacial pain was associated with an inferior localization of ischemia in the heart (p<0.001). In conclusion, this study showed that pain in the craniofacial region could be the sole symptom of cardiac ischemia and AMI, particularly in women. Craniofacial pain of cardiac origin was commonly bilateral, with the quality pain descriptors “pressure” and “burning”, and pain provocation with physical activity and pain relief at rest. The association between the presence of craniofacial pain and inferior wall ischemia suggests a vagal involvement in the mechanisms of cardiac pain referred to the craniofacial region. Since the possibility of misdiagnosis and death in this group of patients is high, awareness of this clinical presentation needs to be brought to the attention of researchers, clinicians and the general public.

Mental illness is common, and usually starts early in life. However, the majority of those affected never seek mental health care. The overall aim of this thesis was to increase knowledge about help-seeking young adults with mental illness in order to improve diagnostic procedures in clinical psychiatry. A group of young adult psychiatric out-patients (n=217) were consecutively invited to participate in the study between October 2002 and September 2003. Altogether 200 (92%) agreed to participate. Among them, there were 161 (80%) women and 39 (20%) men. Participants’ mean age was 22.4±1.9 years. All participants were carefully and comprehensively assessed with respect to axes I, II, IV and V in the DSM-IV. Psychiatric disorders and personality disorders were assessed using the Structured Clinical Interview for DSM-IV for axis I disorders and the Structured Clinical Interview for DSM-IV for axis II disorders. Psychosocial and environmental problems (axis IV) were evaluated through structured interviewing by a social worker and by self-assessment with a questionnaire. Professional and patient ratings on the Global Assessment of Functioning scale were compared before and after treatment. Patients also reported on the Swedish universities Scales of Personality, the Child and Adolescent Psychiatric Screening Inventory-Retrospect and the Coddington’s life event scale. Taken together, the young adult, psychiatric outpatients were characterized by an early onset of their mental disorders, by co-morbidity, by being female and by having mood or anxiety disorders. There were no significant differences between self-referred and those referred by medical professionals according to either number of current or lifetime diagnoses. Childhood onset of depression was associated with more severe symptoms, more psychosocial risk factors, and more childhood developmental delays. Axis IV psychosocial stress categories were related to the presence of axis I disorders, personality disorders, co-morbidity, and impaired functioning. Agreement between patients’ and professionals’ ratings on the GAF scale was good before treatment and excellent after treatment. In summary, the findings suggest that direct self-referral to specialized psychiatric care does not seem to be associated with overutilization of such care. Childhood onset of depression is associated with a more complex illness. The revised axis IV according to DSM-IV seems to have concurrent validity, but is still hampered by limited reliability. And finally, the results support the usefulness of the self-report GAF instrument for measuring outcome in psychiatric care.

Made available in DSpace on 2014-06-11T19:29:33Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-05-26Bitstream added on 2014-06-13T19:38:43Z : No. of bitstreams: 1 baptista_ccwd_me_botfm.pdf: 436274 bytes, checksum: 9718ab06761a44f8ce86a377e88d3850 (MD5) / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / Estudos sobre a utilização de serviços de saúde podem contribuir com a racionalização dos gastos, o planejamento, a reorganização das ações e programas buscando melhorar a qualidade dos serviços prestados. Os inquéritos de saúde de base populacional coletam simultaneamente informações sobre a situação de saúde, as condições de vida, a utilização dos serviços, incorporando informações sobre a população atendida e não atendida, caracterizando a demanda segundo variáveis biológicas, socioeconômicas e geográficas. O estudo da utilização dos serviços de saúde permite conhecer sua acessibilidade para os diversos grupos sócio-econômicos e avaliar a equidade do sistema de saúde. Conhecer o perfil de utilização dos serviços de saúde de Botucatu-SP, em relação à morbidade referida de 15 dias e outros motivos de utilização, segundo características dos usuários e dos serviços procurados. Foram analisados dados, coletados em inquérito de base populacional, relativos à procura de serviços de saúde em amostra populacional urbana de Botucatu, a partir das morbidades referidas e outros motivos, não mórbidos, de procura de serviços de saúde nos últimos 15 dias anteriores a data da entrevista. Os problemas de saúde foram classificados segundo os capítulos da CID 10, sua freqüência e prevalência foram analisadas segundo as variáveis de idade e sexo. Foram estudados a procura de serviços e os motivos da não-procura, o grau de satisfação com o atendimento recebido e a resolubilidade dos problemas de saúde entre os que procuraram e não procuraram os serviços de saúde. Foram caracterizados os serviços procurados, se públicos ou privados, as formas e fontes de pagamento dos atendimentos, de exames solicitados e de medicamentos prescritos. Foram estudadas as variáveis sexo e idade, grau de instrução... / Studies on the use of health services may contribute to reasonable spending, planning, reorganization of actions and programs aiming to improve the quality of delivered services. Populational-based health surveys simultaneously collect information about health condition, life conditions, and the use of services, incorporating information about serviced and non-serviced population, characterizing the demand according to biological, social, economic and geographical variables. The study of the use of health services allows knowing its accessibility to various social and economical groups and evaluating health system equity. To know the profile of the use of health service in Botucatu-SP, related to 15 days referred morbidity and other reasons of use, according to characteristics of users and pursued services. Collected data from a populational-based survey were analyzed and they were related to the pursuit of health services in an urban population sample in Botucatu, from the referred morbidity and other non-morbid reasons of pursuing health services on the last 15 days prior to the day of interview. Health problems were classified according to the chapters of CID 10, its frequency and prevalence were analyzed according to age and sex. The pursued and non-pursued of services, the degree of satisfaction of delivered service and the solution of problems among those who pursued and the ones who did not pursue the services were studied. Pursued services were characterized according to public or private, the ways and sources of service payment, asked examinations and prescribed medications. Variables like sex and age, education degree of the head of the family, and per capita income related to the use of the service were studied. Results: From 1558 interviewed people, 413 (26, 0%) referred one or more health problems... (Complete abstract click electronic access below)

Resumo: Estudos sobre a utilização de serviços de saúde podem contribuir com a racionalização dos gastos, o planejamento, a reorganização das ações e programas buscando melhorar a qualidade dos serviços prestados. Os inquéritos de saúde de base populacional coletam simultaneamente informações sobre a situação de saúde, as condições de vida, a utilização dos serviços, incorporando informações sobre a população atendida e não atendida, caracterizando a demanda segundo variáveis biológicas, socioeconômicas e geográficas. O estudo da utilização dos serviços de saúde permite conhecer sua acessibilidade para os diversos grupos sócio-econômicos e avaliar a equidade do sistema de saúde. Conhecer o perfil de utilização dos serviços de saúde de Botucatu-SP, em relação à morbidade referida de 15 dias e outros motivos de utilização, segundo características dos usuários e dos serviços procurados. Foram analisados dados, coletados em inquérito de base populacional, relativos à procura de serviços de saúde em amostra populacional urbana de Botucatu, a partir das morbidades referidas e outros motivos, não mórbidos, de procura de serviços de saúde nos últimos 15 dias anteriores a data da entrevista. Os problemas de saúde foram classificados segundo os capítulos da CID 10, sua freqüência e prevalência foram analisadas segundo as variáveis de idade e sexo. Foram estudados a procura de serviços e os motivos da não-procura, o grau de satisfação com o atendimento recebido e a resolubilidade dos problemas de saúde entre os que procuraram e não procuraram os serviços de saúde. Foram caracterizados os serviços procurados, se públicos ou privados, as formas e fontes de pagamento dos atendimentos, de exames solicitados e de medicamentos prescritos. Foram estudadas as variáveis sexo e idade, grau de instrução... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: Studies on the use of health services may contribute to reasonable spending, planning, reorganization of actions and programs aiming to improve the quality of delivered services. Populational-based health surveys simultaneously collect information about health condition, life conditions, and the use of services, incorporating information about serviced and non-serviced population, characterizing the demand according to biological, social, economic and geographical variables. The study of the use of health services allows knowing its accessibility to various social and economical groups and evaluating health system equity. To know the profile of the use of health service in Botucatu-SP, related to 15 days referred morbidity and other reasons of use, according to characteristics of users and pursued services. Collected data from a populational-based survey were analyzed and they were related to the pursuit of health services in an urban population sample in Botucatu, from the referred morbidity and other non-morbid reasons of pursuing health services on the last 15 days prior to the day of interview. Health problems were classified according to the chapters of CID 10, its frequency and prevalence were analyzed according to age and sex. The pursued and non-pursued of services, the degree of satisfaction of delivered service and the solution of problems among those who pursued and the ones who did not pursue the services were studied. Pursued services were characterized according to public or private, the ways and sources of service payment, asked examinations and prescribed medications. Variables like sex and age, education degree of the head of the family, and per capita income related to the use of the service were studied. Results: From 1558 interviewed people, 413 (26, 0%) referred one or more health problems... (Complete abstract click electronic access below) / Orientador: Luana Carandina / Coorientador: Antonio Luiz Caldas Junior / Banca: Marilisa Berti de Azevedo Barros / Banca: Carmen Maria C. Monti Julian / Mestre

The StrongARM comparator is utilized in many analog-to-digital converters (ADCs) because of its high power efficiency and rail-to-rail outputs. The performance of the comparator directly affects the speed, power, and accuracy of an ADC. However, the StrongARM comparator performance parameters such as delay, noise, and offset measured directly from silicon prototypes are rare in literature and often consist of small sample sets. In addition, existing techniques to measure the comparator require large chip areas, making it impractical to characterize a large number of comparators to obtain stochastic parameters such as offset and noise. This work presents novel circuit techniques to measure a large number of comparators (4,000) in a compact chip area to directly obtain silicon data including delay, noise, offset, and power. The proposed techniques also relax the requirement on the test instruments to measure the small time values. Four comparators with different transistor size ratios have been designed and measured to study the performance tradeoffs. In addition, this work presents a method utilizing supercomputing resources to simulate the large design space of the StrongARM comparator to observe the performance trends. Measurements are compared to simulations showing their accuracy and, for the first time, detailed study on the performance trends with different transistor size ratios.