京都大学 / 新制・課程博士 / 博士(理学) / 甲第24406号 / 理博第4905号 / 新制||理||1701(附属図書館) / 京都大学大学院理学研究科物理学・宇宙物理学専攻 / (主査)教授 中家 剛, 准教授 WENDELL Roger, 教授 永江 知文 / 学位規則第4条第1項該当 / Doctor of Science / Kyoto University / DFAM

Techniques of beta- and gamma-ray scintillation spectroscopy have been applied to a study of the decay radiations from 92.6-min La142. Several new gamma-ray transitions have been discovered and a gamma-gamma coincidence matrix has been established. Nine beta groups have been identified and evidence is presented substantiating the assignment of a first-forbidden unique character to the ground-state beta transition. Angular correlation studies have been performed on some of the gamma cascades. A decay-scheme based on the experimental results is discussed and some spin assignments are made. Some features of the decay modes are interpreted within the context of contemporary ideas about nuclear structure. / Thesis / Doctor of Philosophy (PhD)

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Ionospheric scintillations can cause significant amplitude and/or phase fluctuations of GNSS signals. This work presents analysis results of scintillation effects on the new GPS L5 signal based on data collected using a real-time scintillation monitoring and data collection system at HAARP, Alaska. The data collection setup includes a custom narrow band front end that collects GPS L1, L2 IF samples and two reconfigurable USRP2 based RF front ends to collect wideband GPS L5 and GLONASS L1 and L2 signals. The results confirm that scintillation has a stronger impact on GPS L2 and L5 signals than on the L1 signal. Our preliminary results also show that carrier phase and amplitude scintillations on each signal are highly correlated. The amplitude and carrier phase scintillation are also correlated among the three signals. In this study, a multi-constellation multi-band GNSS software receiver has been developed based on USRP2, a general purpose radio platform. The C++ class-based software receiver were developed to process the IF data for GPS L1, L2C, and L5 and GLONASS L1 and L2 signals collected by the USRP2 front end. The front end performance is evaluated against the outputs of a high end custom front end driven by the same local oscillator and two commercial receivers, all using the same real signal sources. These results demonstrate that the USRP2 is a suitable front end for applications, such as ionosphere scintillation studies. Another major contribution of this work is the implementation of a Vector tracking loop (VTL) for robust carrier tracking. The VTL is developed based on the extended Kalman filter (EKF) with adaptive covariance matrices. Both scalar tracking loop (STL) and VTL are implemented. Once an error in the scalar loop is detected, the results from the VTL are used to assist the STL. The performance of the VTL is compared with the traditional STL with three different data sets: raw GPS RF data with short signal outages, RF data with strong scintillation impacts collected during the last solar maximum, and high dynamic data with long interval signal outages from a GPS simulator. The results confirm the performance improvement of the VTL over scintillation impacts and show that the VTL can maintain signal lock during long intervals of signal outage if the satellite ephemerides are available and the pseudorange estimation is within one code chip accuracy. The dynamic performance improvement of the VTL is verified as well. The results show the potential of robust tracking based on VTL during scintillation and interference. / Ph. D.

The propagation of radiowaves through ionospheric irregularities can lead to random amplitude and phase fluctuations of the signal, otherwise known as scintillation, which can severely impact the performance of Global Navigation Satellite System (GNSS) and communication systems. Research into high latitude scintillation, through statistical analysis and inverse modeling, was completed to provide insight into the temporal and spatial distribution, and irregularity parameters, which can ultimately support the development of impact mitigation techniques, and deepen our understanding of the underlying physics. The work in this dissertation focused on the statistical analysis of Global Positioning System (GPS) scintillation data, data inversion, two-dimensional (2D) and three-dimensional (3D) scintillation modeling. The statistical analysis revealed distinct trends in the distribution of scintillation, while demonstrating that for GPS signals, phase scintillation occurs most frequently and can be treated as stochastic Total Electron Content (TEC); findings which have significant implications for impact mitigation. For the first of two inversion studies, scintillation data associated with a series of Polar Cap Patches (PCPs), which are common large-scale high latitude structures, was inverted to gain insight into the composition of the underlying irregularities. The results of this study suggest that the irregularities can be modeled as rods interbedded with sheets, which is knowledge that is crucial for the anchoring of models used to develop system mitigation techniques. The final study presents the results of modeling and inversion work to identify the conditions under which a 2D analytic version of the 3D numerical Satellite-beacon Ionospheric-scintillation global model of the upper atmosphere (SIGMA) model can be used to perform modeling in high latitude regions. During the study, it was found that the analytic model tends to diverge for electron density variance times irregularity layer thickness values exceeding 2, matched reasonably well for correlation length to thickness ratios up to 0.2, and was incompatible when ratios approached 0.35. An elevation angle limitation was also identified for the 2D model, and inflated values for the electron density variance were observed overall, which are thought to result from the weak scatter limits of the analytic model. These inflated values were particularly acute in the auroral zone during elevated conditions and suggest that the analytic model used in the study is not well suited for modeling the highly elongated irregularities associated with auroral precipitation. / Doctor of Philosophy / The ionosphere is a region of the earth's atmosphere extending from approximately 90 to 1000 km in altitude. Radio wave signals which travel through irregularities in the ionosphere can be distorted in a way that can lead to random amplitude and phase fluctuations of the signal, otherwise known as scintillation, which can severely degrade the performance of navigation and communication systems. Research into high latitude scintillation, through statistical analysis, and data and model matching, was completed to provide insight into the time and space distribution, and irregularity parameters, in order to ultimately deepen our understanding of the physics and to help develop better models. The work in this dissertation focused on the statistical analysis of GPS scintillation data, data and model matching, and 2D and 3D irregularity modeling. The statistical analysis revealed distinct trends in the distribution of scintillation, while demonstrating that for GPS signals, phase scintillation occurs most frequently but the impacts can be corrected if measured; findings which have significant implications for impact mitigation. For the first of two model and data matching studies, scintillation data associated with a series of common large-scale high latitude structures called PCPs, was matched to a model to gain insight into the composition of the underlying irregularities. The results of this study suggest that the irregularities can be modeled as vertical rods oriented along the magnetic field interbedded within flat sheets, which is knowledge that is crucial for having confidence in the models used to develop system mitigation techniques. The final study presents the results of modeling and data matching work to identify the conditions under which a 2D or 3D model can be used to perform irregularity modeling in the high latitude regions. During the study, it was found that the 2D model tends to diverge from the 3D model for significant variations in the ionosphere, and when irregularity rods are highly elongated. A signal propagation path elevation angle limitation was also identified for the 2D model, and inflated values for the predicted ionospheric variations were observed overall, which are thought to result from limits of the 2D model compared to the more general 3D version. These inflated values were particularly acute in the auroral region during elevated conditions and suggest that the 2D model used in the study is not well suited for modeling the highly elongated irregularities associated with aurora effects.

A full solar eclipse is going to be visible from a range of states in the contiguous United States on August 21, 2017. Since the atmosphere of the Earth is charged by the sun, the blocking of the sunlight by the moon may cause short term changes to the atmosphere, such as density and temperature alterations. There are many ways to measure these changes, one of these being ionospheric scintillation. Ionospheric scintillation is rapid amplitude and phase fluctuations of signals passing through the ionosphere caused by electron density irregularities in the ionosphere. At mid-latitudes, scintillation is not as common of an occurrence as it is in equatorial or high-altitude regions. One of the theories that this paper looks into is the possibility of the solar eclipse producing an instability in the ionosphere that will cause the mid-latitude region to experience scintillations that would not normally be present. Instabilities that could produce scintillation are reviewed and altered further to model similar conditions to those that might occur during the solar eclipse. From this, the satellites that are being used are discuses, as is hardware and software tools were developed to record the scintillation measurements. Although this work was accomplished before the eclipse occurred, measurement tools were developed and verified along with generating a model that predicted if the solar eclipse will produce an instability large enough to cause scintillation for high frequency satellite downlinks. / Master of Science / A full solar eclipse is going to be visible from a range of states in the contiguous United States on August 21, 2017. Since the atmosphere of the Earth is charged by the sun, the blocking of the sunlight by the moon may cause short term changes to the atmosphere, such as density and temperature alterations. There are many ways to measure these changes, one of these being ionospheric scintillation. Ionospheric scintillation is rapid amplitude and phase fluctuations of signals passing through the ionosphere caused by electron density irregularities in the ionosphere. At mid-latitudes, scintillation is not as common of an occurrence as it is in equatorial or high-altitude regions. One of the theories that this paper looks into is the possibility of the solar eclipse producing an instability in the ionosphere that will cause the mid-latitude region to experience scintillations that would not normally be present. Instabilities that could produce scintillation are reviewed and altered further to model similar conditions to those that might occur during the solar eclipse. From this, the satellites that are being used are discuses, as is hardware and software tools were developed to record the scintillation measurements. Although this work was accomplished before the eclipse occurred, measurement tools were developed and verified along with generating a model that predicted if the solar eclipse will produce an instability large enough to cause scintillation for high frequency satellite downlinks.

Depuis une vingtaine d'années, la recherche dans le domaine des nanoobjets pour de l'imagerie et de la thérapie devient de plus en plus importante. En effet, les nanoparticules présentent de nombreux avantages par rapport aux composés moléculaires : leur temps de résidence dans le système sanguin est plus long ; la nanoparticule peut contenir une grande quantité de molécules actives ; les nanoparticules peuvent contenir plusieurs fonctionnalités grâce à leur multimodalité ; et elles peuvent s'accumuler dans les zones cibles grâce à un ciblage passif ou actif. Dans ce cadre, nous proposons une nouvelle structure hybride AGuIX® de taille inférieure à 5 nm, constituée d'une matrice de polysiloxane à la surface de laquelle sont greffés des complexes de gadolinium et des ligands libres. Ces nanoparticules ont été développées pour des applications en imagerie (IRM, scintigraphie, fluorescence) ainsi que des applications en thérapie (radiothérapie). Le but de la thèse consiste d'une part à maîtriser le mécanisme de synthèse, caractériser les nanoparticules par le développement de techniques originales et enfin à exploiter les propriétés multimodales de la nanoparticule afin de proposer plusieurs solutions en imagerie et en thérapie. Les tests biologiques montrent un fort potentiel des nanoparticules pour des applications biologiques. Dans un premier temps, les nanoparticules ont été couplées à des photosensibilisateurs afin d'induire un autre mode de thérapie : la PDT. Ce couplage a permis de travailler sur les mécanismes physiques opérant dans ce modèle. Afin de proposer une dualité en imagerie, les particules AGuIX® ont été marquées par différents isotopes radioactifs. Pour cela, la nanoparticule a été modifiée par l'ajout de ligands spécifiques complexant certains isotopes. Cette étude a abouti également sur le recherche d'un autre mode de thérapie possible avec les AGuIX® : la curie thérapie / Nanoparticles research has become one of the most promising way for biological applications. They present alternative solutions to the traditional diagnostic and therapeutic methods thanks to (i) their appropriate size and surface which can enhance circulation time in the blood, (ii) their large compartments able to contain considerable amounts of imaging or drugs agents, (iii) their multimodality which makes them potential multifunctional nanoplatforms for both diagnosis and therapy (theranostic), (iv) their capacity to target disease by their appropriate size and surface of by specific targeting moieties grafted on their surface. We propose a new sub-5 nanometer nanoparticles multimodal nanoparticle (called AGuIX®), composed of a polysiloxane network surrounded by gadolinium chelates and free chelates. They have previously demonstrated their efficiency for multimodal imaging and theranostic applications, especially MRI, scintigraphy and fluorescence imaging and radiotherapy. The aim of the thesis was to characterize the synthesis and the nanoparticles in order then to explore the multi-possibilities of therapy and imaging of these nanoparticles AGuIX®. Original characterizations technics were developed. The intrinsic measured properties of AGuIX® solutions fulfill the conditions for potential clinical applications, a wide series of biological tests have been performed. Then first, the coupling of the AGuIX® with another therapy method was explored: PDT effect with photosensitizers grafting on the surface of the nanoparticles. A good understanding of the mechanism was studied. The multimodality of imaging was tested by the labeling with radioactive elements on the surface of the nanoparticles. It was necessary to use a specific ligand in order to obtain high labeling yield. The coupling MRI/scintigraphy is one of the major field in order to have an imaging agent with high resolution and high sensitivity. This study was the opportunities to try to couple another therapy technic: brachytherapy