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Microstructure and Chemistry Evaluation of Direct Metal Laser Sintered 15-5 PH Stainless SteelCoffy, Kevin 01 January 2014 (has links)
15-5PH stainless steel is an important alloy in the aerospace, chemical, and nuclear industries for its high strength and corrosion resistance at high temperature. Thus, this material is a good candidate for processing development in the direct metal laser sintering (DMLS) branch of additive manufacturing. The chemistry and microstructure of this alloy processed via DMLS was compared to its conventionally cast counterpart through various heat treatments as part of a characterization effort. The investigation utilized optical microscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-Ray diffractometry (XRD), energy dispersive X-Ray spectroscopy (EDS) and glow discharge atomic emission spectrometry (GDS) techniques. DMLS processed samples contained a layered microstructure in which the prior austenite grain sizes were relatively smaller than the cast and annealed prior austenite grain size. The largest of the quantifiable DMLS prior austenite grains had an ASTM grain size of approximately 11.5-12 (6.7?m to 5.6?m, respectively) and the cast and annealed prior austenite grain size was approximately 7-7.5 (31.8µm to 26.7µm, respectively), giving insight to the elevated mechanical properties of the DMLS processed alloy. During investigation, significant amounts of retained austenite phase were found in the DMLS processed samples and quantified by XRD analysis. Causes of this phase included high nitrogen content, absorbed during nitrogen gas atomization of the DMLS metal powder and from the DMLS build chamber nitrogen atmosphere. Nitrogen content was quantified by GDS for three samples. DMLS powder produced by nitrogen gas atomization had a nitrogen content of 0.11 wt%. A DMLS processed sample contained 0.08 wt% nitrogen, and a conventionally cast and annealed sample contained only 0.019 wt% nitrogen. In iron based alloys, nitrogen is a significant austenite promoter and reduced the martensite start and finish temperatures, rendering the standard heat treatments for the alloy ineffective in producing full transformation to martensite. Process improvements are proposed along with suggested future research.
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Impact de la préservation à froid et du réchauffement sur les mécanismes de régulation du volume cellulaire, le système de transport des acides aminés et les capacités métaboliques oxidatives hépatiquesSerrar, Halima January 1999 (has links)
Thèse numérisée par la Direction des bibliothèques de l'Université de Montréal. / L'échec de la transplantation est dû en partie aux dormnages causés par la
préservation à froid et la réperfiision à chaud lors de l'intervention. Parmi les hypothèses
retenues pour expliquer ces dommages, on retient la formation des radicaux libres et les
perturbations du pH, du calcium et du volume cellulaire. L'ajout de certaines substances
dans le milieu de préservation a permis de prolonger de 6h à 24h la survie de l'organe.
Malgré le développement de solutions de préservation qui diminuent le gonflement
cellulaire des foies à transplanter, les dommages de la reperfusion chaude ne sont pas
abolis. Il se peut donc, que l'hypothermie anoxique altère les mécanismes de régulation du
volume cellulaire et que ces perturbations contribuent aux dommages observés lors de la
reperfusion du greffon chez le receveur.
Afin de vérifier cette hypothèse, nous avons vérifié dans le premier chapitre si les
conditions de la préservation à froid suivie du réchauffement entravaient la diminution ou
l'augmentation compensatrice de volume observé respectivement après un choc
hypotonique (retrait de 50 mmol de NaC1). Notre étude démontre que les hépatocytes
préservés dans la solution de l'Université de Wisconsin (UM.) ont été moins résistants
aux stress osmotiques, ce qui peut rendre les cellules moins aptes à répondre aux
stimulations physiologiques comme l'accumulation des acides aminés, spécialement lors
des demandes métaboliques et l'alimentation parentérale riche en acides aminés. Ceci
devrait être confirmé dans les conditions in vivo. Cependant, nos résultats supportent la
notion que la perturbation du volume cellulaire homéostasique peut correspondre au dysfonctionnement primaire observé dans 15% des cas lors de la transplantation
hépatique.
Subséquemment, nous avons étudié l'impact de la préservation et la réperfusion à
chaud sur le transport hépatique d'acides aminés couplés au Na ( 1 0 mM). Nous avons
mesuré par la technique de vidéoplanimétrie les changements initiaux de volume qui
reflètent l'accumulation des acides aminés. Nous avons constaté qu'en fonction du temps
de préservation les transporteurs sont affectés différemment. Le gonflement induit par la
proline, substrat spécifique du système ASC est très sensible à la préservation à froid
dans la solution U.W. chutant de 50 % après 24h de préservation comparée avec le
contrôle sans préservation, en opposition à la glutamine ou à l'analogue de l'alanine. Ceci
nous a conduit à proposer que le gonflement induit par la proline représente un index
fonctionnel sensible de l'intégrité des cellules du foie.
Dans le second chapitre, nous avons comparé l'efficacité de la solution U.W. et la
solution Sodium-Lactobionate-Sucrose (SLS) dans leurs capacités à maintenir la viabilité
cellulaire et une fonction différenciée des cellules du foie (gonflement induit par
l'addition de 10 mM de Proline, substrat spécifique du système ASC).
Enfin, dans le troisième chapitre, nous avons comparé l'effet de ces deux
solutions (U.W./SLS) sur le métabolisme des médicaments et l'activité catalytique du
cytochrome P-450 au niveau des cellules isolées de foie de rat. Cette activité catalytique
est calculée par la mesure de la concentration totale du cytochrome P-450 et des
métabolites de la théophylline générés après 4h d'incubation. La théophylline est utilisée car elle est métabolisée par plusieurs isoformes du cytochrome P-450: cytochrome P-450 1A2,
2D6, 2E1 et 3A4 dont l'aboutissement est le 1,3-DMU qui est son métabolite majeur.
Nous avons noté que la majorité de perturbations observées dans notre modèle in
vitro est entre 10 et 24 h de préservation à froid des hépatocytes dans les deux solutions
(U.W./SLS). Ceci correspond à la période 12 h de préservation à froid des foies humains
dans la solution U.W., qui représente un facteur de risque relatif pour un mauvais
pronostic, responsable de dysfonctionnement primaire observé dans 15% des cas lors de
la transplantation hépatique.
Nos données démontrent clairement que la préservation à froid des hépatocytes
dans la solution SLS, préparée au laboratoire à coût très réduit, donne des résultats
équivalent à ceux de la solution U.W. (commercialisée par Dupont) quant à sa capacité à
maintenir la viabilité cellulaire, l'intégrité fonctionnelle des cellules du foie et le
métabolisme des médicaments.
Ceci suggère que la solution SLS, qui n'est qu'une variante de la solution U.W.,
est suffisante pour obtenir les effets bénéfiques de préservation de la solution élaborée
expérimentalement (Belzer et Southard, 1988). Donc certains composants de la solution
U.W. ne peuvent apporter aucun impact bénéfique comparé à la solution SLS à
composition beaucoup plus simple. Une approche intéressante pourrait être établie sur
une solution aussi simple que la SLS à laquelle des agents pharmacologiques et
cytoprotecteurs peuvent être ajoutés. Ceci permettra de maintenir l'efficacité des
fonctions hépatiques et d'améliorer la survie des greffes du foie, menant ainsi à un
meilleur pronostic de la transplantation du foie.
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Serviceability Behaviour of Reinforced UHPFRC Tensile ElementsKhorami, Majid 03 April 2023 (has links)
Tesis por compendio / [ES] Todas estructuras, especialmente las conformadas con hormigón armado, no solo deben cumplir con la seguridad necesaria bajo los Estados Límites Últimos (ULS), además es imprescindible que garanticen un comportamiento adecuado frente a condiciones de servicio. En general, los requisitos fundamentales de servicio que debe cumplir este tipo de estructuras son: la funcionalidad, comodidad para el usuario y la apariencia. Sin embargo, estos no se pueden verificar de forma directa; por lo tanto, ha sido necesario definir criterios de desempeño tales como control de deflexión, control de vibración y control de agrietamiento para dar cumplimiento a lo indicado anteriormente.
Además, se dificulta el cálculo de la capacidad de servicio debido al fenómeno de agrietamiento, el efecto de rigidez por tensión, la contracción y los efectos de fluencia. Por lo tanto, el control de la fisuración en estructuras de hormigón armado generalmente se logra limitando la tensión en el refuerzo de acero y la matriz de hormigón. Siendo así que, en los diseños incluidos en códigos relevantes a hormigón, especifican la tensión máxima del refuerzo de acero después de la fisuración y el ancho máximo de fisura para los miembros estructurales de CR o FRC, no obstante los aspectos de capacidad de servicio del diseño para el hormigón reforzado con fibras de ultra alto rendimiento reforzado (R-UHPFRC), no han sido incluidos en los códigos o recomendaciones de UHPFRC.
A pesar de que se han realizado muchos esfuerzos en la investigación tanto experimental como teórica sobre el comportamiento de servicio de los elementos estructurales de CR o FRC durante las últimas décadas, para el R-UHPFRC se debe desarrollar aún más su conocimiento relacionado con los requisitos para el diseño de capacidad de servicio, incluyendo su comportamiento de tensión y agrietamiento.
En este marco, el objetivo principal de la presente tesis doctoral es evaluar el comportamiento de servicio de R-UHPFRC. Por tal razón, es fundamental realizar la evaluación del comportamiento de deformación y fisuración de los elementos de tracción R-UHPFRC. Para ello, se abordaron y cumplieron adecuadamente dos puntos principales. El primero, diseñar una metodología de prueba innovadora y adecuada para ejecutar los experimentos requeridos para este proyecto de doctorado. En segundo lugar, se llevó a cabo la evaluación de la respuesta de rigidez a la tensión y el comportamiento de agrietamiento del R-UHPFCR, que son parámetros primordiales para el diseño de capacidad de servicio. Para estudiar estos dos parámetros, se consideraron algunos parámetros importantes tales como: el efecto del volumen del contenido de fibra, el tipo de fibra, el efecto del tamaño, el efecto de la relación de refuerzo y el efecto de la contracción.
Finalmente, para evaluar los parámetros mencionados, se presentan cuatro campañas experimentales. Cada una de ellas, representa un nivel diferente de estudio. El primero corresponde a la validación de la metodología de ensayo de tracción propuesta y examinar los datos experimentales obtenidos, para emplearlos en futuros estudios de este proyecto. El segundo nivel consistió en establecer y realizar experimentos completos con dos tipos de fibra de acero, modificando además su cantidad, es así como se utilizaron diferentes proporciones de refuerzo y sección transversal para evaluar el efecto tanto del tamaño como del contenido de fibra, respectivamente. También, en un estudio experimental específico se indagó sobre el efecto de la combinación de micro y microfibras de acero en la deformación y el comportamiento de agrietamiento de los elementos R-UHPFRC de tracción. El tercer nivel corresponde a una prueba de contracción intensiva, necesaria para obtener el valor de contracción del UHPFRC utilizado en esta investigación. El último nivel comprende la modificación de la geometría de la probeta y el uso de probetas en forma de hueso de perro para evaluar el ancho medio y máximo de fisura (valor / [CA] Totes les estructures, especialment les conformades amb formigó armat, no només han de complir amb la seguretat necessària sota els Estats Límits Últims (ULS), a més és imprescindible que garanteixin un comportament adequat davant de condicions de servei. En general, els requisits fonamentals de servei que ha de complir aquest tipus d'estructures són: la funcionalitat, la comoditat per a l'usuari i l'aparença. Això no obstant, aquests no es poden verificar de forma directa; per tant, ha calgut definir criteris d'acompliment com ara control de deflexió, control de vibració i control d'esquerdament per a donar compliment al que s'ha indicat anteriorment.
A més, es dificulta el càlcul de la capacitat de servei a causa del fenomen d'esquerdament, l'efecte de rigidesa per tensió, la contracció i els efectes de fluència. Per tant, el control de la fissuració en estructures de formigó armat generalment s'aconsegueix limitant la tensió al reforç d'acer i la matriu de formigó. És així que en els dissenys inclosos en codis rellevants a formigó, especifiquen la tensió màxima del reforç d'acer després de la fissuració i l'amplada màxima de fissura per als membres estructurals de CR o FRC, no obstant els aspectes de capacitat de servei del disseny per al formigó reforçat amb fibres d'ultra alt rendiment reforçat (R-UHPFRC), no han estat inclosos als codis o recomanacions d'UHPFRC.
Tot i que s'han realitzat molts esforços en la investigació tant experimental com teòrica sobre el comportament de servei dels elements estructurals de CR o FRC durant les últimes dècades, per al R-UHPFRC s'ha de desenvolupar encara més el seu coneixement relacionat amb els requisits per al disseny de capacitat de servei, incloent el comportament de tensió i esquerdament.
En aquest marc, l'bjectiu principal de la present tesi doctoral és avaluar el comportament de servei de R-UHPFRC. Per aquesta raó, és fonamental fer l'avaluació del comportament de deformació i fissuració dels elements de tracció R-UHPFRC. Per això, es van abordar i van complir adequadament dos punts principals. El primer, dissenyar una metodologia de prova innovadora i adequada per executar els experiments requerits per a aquest projecte de doctorat. En segon lloc, es va fer l'avaluació de la resposta de rigidesa a la tensió i el comportament d'esquerdament del R-UHPFCR, que són paràmetres primordials per al disseny de capacitat de servei. Per estudiar aquests dos paràmetres, es van considerar alguns paràmetres importants com ara l'efecte del volum del contingut de fibra, el tipus de fibra, l'efecte de la mida, l'efecte de la relació de reforç i l'efecte de la contracció.
Finalment, per avaluar els paràmetres mencionats, es presenten quatre campanyes experimentals. Cadascuna representa un nivell diferent d'estudi. El primer correspon a la validació de la metodologia dassaig de tracció proposada i examinar les dades experimentals obtingudes, per a emprar-les en futurs estudis daquest projecte. El segon nivell va consistir a establir i realitzar experiments complets amb dos tipus de fibra d'acer, modificant-ne a més la quantitat, és així com es van utilitzar diferents proporcions de reforç i secció transversal per avaluar l'efecte tant de la mesura com del contingut de fibra, respectivament. També, en un estudi experimental específic, es va indagar sobre l'efecte de la combinació de micro i macrofibres d'acer en la deformació i el comportament d'esquerdament dels elements R-UHPFRC de tracció. El tercer nivell correspon a una prova de contracció intensiva, necessària per obtenir el valor de contracció de l'UHPFRC utilitzat en aquesta investigació. L'últim nivell comprèn la modificació de la geometria de la proveta i l'ús de provetes en forma d'os de gos per avaluar l'amplada mitjana i màxima de fissura (valor real detectat) provocat per esforços de tracció en els elements de tracció R-UHPFRC . És important esmentar que es van fer diferents anàlisis per a cada investigació experimental i es van ac / [EN] All structures, particularly reinforcement concrete structures, apart from meeting necessary security against Ultimate Limit States (ULS), must exhibit appropriate behaviour under service conditions. Generally, the fundamental serviceability requirements that concrete structures should meet are functionality, user comfort and appearance. These requirements cannot, however, be directly checked. Therefore, performance criteria, such as deflection control, vibration control and cracking control, are defined to meet these requirements.
Serviceability calculation is complicated because of the cracking phenomenon, the tension stiffening effect, shrinkage, and creep effects. Cracking control in reinforced concrete (RC) structures is generally achieved by limiting stress in steel reinforcement and the concrete matrix. Many concrete code designs specify a maximum steel reinforcement stress after cracking and a maximum crack width for RC or fibre-RC (FRC) structural members, while the design serviceability aspects for Reinforced Ultra-High Performance Fibre-Reinforced Concrete (R-UHPFRC) are poorly considered in UHPFRC codes or recommendations.
Many efforts have been made in experimental and theoretical research into the serviceability behaviour of RC or FRC structural elements in the last few decades. However, for R-UHPFRC, knowledge about tension and cracking behaviour must improve and serviceability design requirements have to be further studied.
Within this framework, the main purpose of the present PhD thesis is to evaluate the serviceability behaviour of R-UHPFRC. For this purpose, the evaluation of the deformation and cracking behaviour of R-UHPFRC tensile elements is essential. To that end, two main items were addressed and adequately met. The first one was to design an innovative and adequate test methodology to carry out the experiments required for this PhD project. The second involved evaluating the tension stiffening response and cracking behaviour of R-UHPFRC, which are fundamental parameters for R-UHPFRC structures' serviceability design. To study these two parameters, important parameters were considered, such as fibre content, fibre type, size effect, reinforcement ratio and shrinkage effect.
In order to evaluate the aforementioned parameters, four experimental campaigns are presented. Each campaign represents a different study level. The first corresponds to the validation of the proposed tensile test methodology and to the examination of the obtained experimental data for future studies required for this PhD project. The second experimental study level corresponds to establishing and undertaking comprehensive experimental programmes with two different steel fibre types and fibre contents. Different cross-section and reinforcement ratios were used to evaluate the size effect and fibre content effect, respectively. The effect of the micro- and macro-steel fibres combination on the deformation and cracking behaviour of tensile R-UHPFRC elements was investigated in a specific experimental study. The third level corresponds to an intensive shrinkage test, which was conducted to obtain the shrinkage value of the UHPFRC used in this PhD study. The final level corresponds to a specific experimental study, done by modifying the specimen's geometry and using the dog bone-shaped specimens to evaluate the average and maximum crack width (real detected value) caused by tensile stresses in R-UHPFRC tensile elements. It is worth mentioning that different analyses were performed for each experimental research and appropriate results were achieved to fulfil the thesis aims.
Keywords: cracking behaviour, design criteria, durability, fragility curve, post-cracking tensile stiffness, serviceability behaviour, shrinkage, SLS requirements, structural design, tensile elements, tension stiffening, test method, tie, UHPFRC. / This work is part of Project “BIA2016-78460-C3-1-R” supported by the State Research Agency of Spain / Khorami, M. (2023). Serviceability Behaviour of Reinforced UHPFRC Tensile Elements [Tesis doctoral]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/192683 / Compendio
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A FRAMEWORK FOR OPTIMIZING PROCESS PARAMETERS IN POWDER BED FUSION (PBF) PROCESS USING ARTIFICIAL NEURAL NETWORK (ANN)Mallikharjun Marrey (7037645) 15 August 2019 (has links)
<p>Powder bed fusion (PBF)
process is a metal additive manufacturing process, which can build parts with
any complexity from a wide range of metallic materials. Research in the PBF
process predominantly focuses on the impact of a few parameters on the ultimate
properties of the printed part. The lack of a systematic approach to optimizing
the process parameters for a better performance of given material results in a
sub-optimal process limiting the potentialof the application. This process
needs a comprehensive study of all the influential parameters and their impact
on the mechanical and microstructural properties of a fabricated part.
Furthermore, there is a need to develop a quantitative system for mapping the
material properties and process parameters with the ultimate quality of the
fabricated part to achieve improvement in the manufacturing cycle as well as
the quality of the final part produced by the PBF process. To address the
aforementioned challenges, this research proposes a framework to optimize the process
for 316L stainless steel material. This framework characterizes the influence
of process parameters on the microstructure and mechanical properties of the
fabricated part using a series of experiments. These experiments study the
significance of process parameters and their variance as well as study the microstructure
and mechanical properties of fabricated parts by conducting tensile, impact,
hardness, surface roughness, and densification tests, and ultimately obtain the
optimum range of parameters. This would result in a more complete understanding
of the correlation between process parameters and part quality. Furthermore,
the data acquired from the experimentsare employed to develop an intelligent
parameter suggestion multi-layer feedforward (FF) backpropagation (BP)
artificial neural network (ANN). This network estimates the fabrication time
and suggests the parameter setting accordingly to the user/manufacturers
desired characteristics of the end-product. Further, research is in progress to
evaluate the framework for assemblies and complex part designs and incorporate
the results in the network for achieving process repeatability and consistency.</p><br>
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Numerical modeling and simulation of selective laser sintering in polymer powder bed / Modélisation numérique et simulation du frittage par laser dans les poudre polymèreLiu, Xin 28 February 2017 (has links)
La fabrication additive est l’un des secteurs industriels les plus en développent ces dernières années. L’une de ces technologies de fabrication les plus prometteuses est la fusion laser sélective (SLS), et relève d’un intérêt croissant aussi bien industriel qu’académique. Néanmoins, beaucoup de phénomène mis en jeu par ce procédé demeure non encore bien compris, entravant ainsi son développement pour la production de pièces de bonne qualité pour des applications industrielles. L’objectif de cette thèse est de développer un cadre de simulation numérique permettant la simulation du procédé SLS pour des poudres de polymère afin de comprendre les multiples et complexes phénomènes physiques qui se produise lors du frittage laser et d’étudier l’influence des paramètres du procédé sur la qualité du produit final. Contrairement aux approches classiques de modélisation numérique, basées sur la définition de matériaux homogène équivalents pour la résolution des équations de bilan, nous proposons une simulation globale du procédé du frittage laser de poudres, en utilisant la méthode des Eléments Discrets (DEM). Cela consiste en un couplage entre quatre sous-modèles : transferts radiatif dans le milieu granulaire semi-transparent, conduction thermique dans les milieux discrets, coalescence puis densification. Le modèle de transferts par rayonnement concerne l’interaction du faisceau laser avec le lit de poudre. Plusieurs phénomènes sont ainsi pris en compte, notamment la réflexion, la transmission, l’absorption et la réfraction. De plus, une méthode de Monte-Carlo couplée à la méthode du Lancer de rayons est développée afin d’étudier l’influence de la réfraction sur la distribution de l’énergie du laser dans le lit de poudre. Le modèle de conduction dans des milieux discrets décrit la diffusion thermique inter-particules. Finalement, le modèle de frittage décrit les cinétiques de coalescence et de diffusion de l’air dans le polymère et densification du milieu. Cela permet de décrire les cinétiques de fusion des grains, dont l’énergie de surface et la diffusons de l’air sont les deux moteurs principaux. Le couplage entre les différents modèles nous a permis de proposer un modèle numérique global, validé grâce à des comparaisons à des résultats de simulations théoriques et expérimentales, trouvés dans la littérature. Une analyse paramétrique est alors proposée pour la validation du modèle et l’étude du procédé. L’influence de différents paramètres aussi bien du procédé que du matériau sur le champ de température, la densité relative du matériau sa structure, etc , est ainsi investiguée. Les résultats montrent une bonne précision dans la modélisation des différents phénomènes complexes inhérents à ce procédé, et ce travail constitue un potentiel réel pour la modélisation et l’optimisation des procédés de fabrication additive par matériaux granulaires. / Many industrial and academic interests concerning the additive manufacturing processes are developed in the last decades. As one of the most promising technique of additive manufacturing, the Selective Laser Sintering (SLS) has been valued by both industry and academic. However, it remains that several phenomena are still not well understood in order to properly model the process and propose quality improvement of parts made. The goal of this Ph.D. project is to develop a framework of numerical simulation in order to model the SLS process in polymer powder bed, meanwhile understanding multiple physical phenomena occurring during the process and studying the influence of process parameters on the quality of final product. In contrast to traditional approach, based on the equivalent homogeneous material in numerical modeling of partial differential equations derived from conservation laws, we propose a global model to simulate powder-based additive manufacturing by using the Discrete Element method (DEM). It consists in a coupling between four different physical models: radiative heat transfer, discrete heat conduction, sintering and granular dynamics models. Firstly, the submodel of radiative heat transfer concerns the interaction between the laser beam and powder bed. Several phenomena are considered, including the reflection, transmission, absorption and scattering. Besides, a modified Monte Carlo ray-tracing method is developed in order to study the influence of scattering on the distribution of the deposited laser energy inside the powder bed Furthermore, the submodel of discrete heat conduction describes the inter-particles heat diffusion. Moreover, the sintering submodel concerns the phenomena of coalescence and air diffusion. It describes the melting kinetics of grains, driven by surface tension and the release of entrapped gases inside powder bed. Finally, the granular dynamics submodel concerns the motions and contacts between particles when depositing a new layer of powders. The coupling between these submodels leads to propose a global numerical framework, validated by comparing the results to both simulated and experimental ones from literatures. A parametric study is then proposed for model validation and process analysis. The Influence of different material and process parameters on the evolution of temperature, relative density and materials structure and characteristics are investigated. The results exhibit accurate modeling of the complex phenomena occurring during the SLS process, and the work constitute a great potential in modeling and optimization of additive processes.
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Most na silnici I/11 / Bridge on the I/11 roadJedlička, Martin January 2016 (has links)
Aim of this thesis is to design a concrete road bridge over a Neborůvka stream and surrounding valley. This bridge is a part of I/11 road. Three preliminary designs with focus on girder bridge solution were made. As a most suitable variant was chosen two gilder beams variant. For this variant was made a static calculation concerning TDA. This design was made according EC. As a construction method was chosen classic construction with falsework. Design was made in Midas Civil and Dlubal RFEM calculation software. As a next step a drawing documentation was made as well as construction time plan and bridge visualization.
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Stabilita systémů pro řízené uvolňování léčiv na bázi plastifikovaného škrobu / Stability of controlled drug release systems based on plasticized starchZhukouskaya, Hanna January 2022 (has links)
The thesis is focused on the research of stability of controlled drug release systems based on a blend of plasticized starch/polycaprolactone (TPS/PCL) that served as a carrier. Antibiotic vancomycin was used as a model drug, and its release from TPS/PCL pellets into aqueous environment was followed by UV-spectroscopy and the obtained time dependences were treated by a simple kinetic model. Moreover, the simultaneous release of starch particles to the surrounding liquid phase was studied by static and dynamic light scattering as well as transmission electron microscopy (TEM) in order to obtain information on the stability of biodegradable matrix and on the structure of the products of the pellet decomposition on a nanoscale level. Key words: vancomycin, starch, drug delivery system, polycaprolactone (PCL), particle release, dynamic light scattering (DLS), static light scattering (SLS)
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The Design And Development Of An Additive Fabrication Process And Material Selection ToolPalmer, Andrew 01 January 2009 (has links)
In the Manufacturing Industry there is a subset of technologies referred to as Rapid Technologies which are those technologies that create the ability to compress the time to market for new products under development . Of this subset, Additive Fabrication (AF), or more commonly known as Rapid Prototyping (RP), acquires much attention due to its unique and futuristic approach to the production of physical parts directly from 3D CAD data, CT or MRI scans, or data from laser scanning systems by utilizing various techniques to consecutively generate cross-sectional layers of a given thickness upon the previous layer to form 3D objects. While Rapid Prototyping is the most common name for the production technology it is also referred to as Additive Manufacturing, Layer Based Manufacturing, Direct Digital Manufacturing, Free-Form Fabrication, and 3-Dimensional Printing. With over 35 manufacturers of Additive Fabrication equipment in 2006 , the selection of an AF process and material for a specific application can become a significant task, especially for those with little or no technical experience with the technology and to add to this challenge, many of the various processes have multiple material options to select from . This research was carried out in order to design and construct a system that would allow a person, regardless of their level of technical knowledge, to quickly and easily filter through the large number of Additive Fabrication processes and their associated materials in order to find the most appropriate processes and material options to create physical reproductions of any part. The selection methodology used in this paper is a collection of assumptions and rules taken from the author's viewpoint of how, in real world terms, the selection process generally takes place between a consumer and a service provider. The methodology uses those assumptions in conjunction with a set of expert based rules to direct the user to a best set of qualifying processes and materials suited for their application based on as many or as few input fields the user may be able to complete.
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Innovative Tessellation Algorithm for Generating More Uniform Temperature Distribution in the Powder-bed Fusion ProcessEhsan Maleki Pour (5931092) 16 January 2019 (has links)
<div>Powder Bed Fusion Additive Manufacturing enables the fabrication of metal parts with complex geometry and elaborates internal features, the simplication of the assembly process, and the reduction of development time. However, the lack of consis-tent quality hinders its tremendous potential for widespread application in industry. This limits its ability as a viable manufacturing process particularly in the aerospace and medical industries where high quality and repeatability are critical. A variety of defects, which may be initiated during the powder-bed fusion additive manufacturing process, compromise the repeatability, precision, and resulting mechanical properties of the final part. The literature review shows that a non-uniform temperature distribution throughout fabricated layers is a signicant source of the majority of thermal defects. Therefore, the work introduces an online thermography methodology to study temperature distribution, thermal evolution, and thermal specications of the fabricated layers in powder-bed fusion process or any other thermal inherent AM process. This methodology utilizes infrared technique and segmentation image processing to extract the required data about temperature distribution and HAZs of the layer under fabrication. We conducted some primary experiments in the FDM process to leverage the thermography technique and achieve a certain insight to be able to propose a technique to generate a more uniform temperature distribution. These experiments lead to proposing an innovative chessboard scanning strategy called tessellation algorithm, which can generate more uniform temperature distribution and diminish the layer warpage consequently especially throughout the layers with either geometry that is more complex or poses relatively longer dimensions. In the next step, this work develops a new technique in ABAQUS to verify the proposed scanning strategy. This technique simulates temperature distribution throughout a layer printed by chessboard printing patterns in powder-bed fusion process in a fraction of the time taken by current methods in the literature. This technique compares the temperature distribution throughout a designed layer printed by three presented chessboard-scanning patterns, namely, rastering pattern, helical pattern, and tessellation pattern. The results conrm that the tessellation pattern generates more uniform temperature distribution compared with the other two patterns. Further research is in progress to leverage the thermography methodology to verify the simulation technique. It is also pursuing a hybrid closed-loop online monitoring (OM) and control methodology, which bases on the introduced tessellation algorithm and online thermography in this work and Articial Neural Networking (ANN) to generate the most possible uniform temperature distribution within a safe temperature range layer-by-layer.</div>
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Návrh předpjatého komorového mostu / Design of prestressed box gireder bridgeHofírek, Radovan January 2013 (has links)
This thesis deals with bridging of a lowland valley and the creek Dolanský in the section Jánovce – Jablonov on the Slovak motorway D1. Four variants of the bridge have been developed. Subsequently prestressed single box gilder with large overhangs that are supported by precast struts was selected as the most suitable variant. The construction of the bridge will take place in a formwork suspended on overhead launching scaffolding. The static assessment according to the Europan standard has been drawn up for this variant. The load of the bridge is projected according to the ČSN EN 1991-2 - Traffic loads on bridges and the dimensoin of concrete structures according to the ČSN EN 1992-2 - Concrete bridges - Design and detailing rules. The calculation of load is done using computer software SCIA Engineer 10.1 and Midas Civil.
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