Thesis (PH. D.)--University of Pennsylvania, 1933. / Published also without thesis note. Bibliography: p. 115-117.

Thesis (Ph. D.)--University of Washington, 1997. / Vita. Includes bibliographical references (leaves [105]-117).

La recherche proposée mène une analyse des processus de mondialisation qui intéressent la ville de Tanger et des conséquentes luttes de femmes des quartiers populaires contre les effets du développement néo-libéral sur le territoire. À partir d'une dimension internationale, liée spécifiquement aux discours sur la constitution de la macro-région méditerranéenne, j’insiste sur la manière dont les politiques de privatisation et d'accaparement des IDE Investissements Directs Étrangers ont produit des conséquences importantes surtout dans la région du Nord. Au nom de la politique de régionalisation et à la lumière du rôle central reconnu désormais à la géographie méditerranéenne, la région nord est le territoire où les plans méditerranéens se mettent en place: des nombreuses zones franches et industrielles ont vu le jour et par conséquent une forte migration des campagnes vers les villes a créé une urbanisation toujours croissante. La recherche ethnographique a été développée à Tanja, le principal centre urbain de la région nord, où une série de luttes populaires à grande participation féminine a eu lieu. Je les analyse en les contextualisant avec les projets de développement qui intéressent la zone. A l’aide d’une observation participante et d’une série d’interviews individuelles et de groupes, j’indique des parcours de réflexion autour de certains axes thématiques, tels que l'autorité, la protestation, la façon de traverser l’espace. La dernière partie consiste dans l’application de la méthode déconstructionniste sur un signifiant spécifique qui ressort, même si situé différemment, des récits des femmes interviewées: la maison. / Here proposed un analysis of the development projects concerning the city of Tangier and the struggles of the women living in the popular zones.Starting from an international dimension, which is particularly related to the construction of the Mediterranean region, I underline how the privatization processes and the FDI Foreign Direct Investments grabbing, produced deep consequences especially in the Northern region of Morocco. Connecting to the regionalization process and the central role of the Mediterranean geography, the region is the territory for the implementation of Mediterranean projects: installation of industrial and free zones that produces the increase of the internal migration (from countryside to city) with the consequent progressive urbanization of the region.The ethnographic research took place in Tanja, the main urban centre of the North where different popular fights, with a predominant women’s participation, occur. The narration of these struggles is in a constant dialogue with insights on some specific development projects Some lines of thought around thematic aces like authority, protest and space crossing are identified through a methodology of participant observation and several semi-structured interviews with the women implicated in the struggles.The last part of the work consist in applying the deconstructionist method to a specific signifier: the home.

In 1982, the International Monetary Fund (IMF) led structural adjustment of the Moroccan state; the culmination of prolonged war in the Western Sahara, unstable agricultural productivity and unstable debt inflation. Since then, deep political economic reorganization has transformed the institutional, practical and physical articulation of urban management in the state. This study situates managerial shifts within an urban globalization context, with specific reference to Tangier. While Tangier?s urban development parallels many studies from the developing and less-developed world, its place-specific formation diverges because globalizing urban management is undertaken within the context of historically and geographically specific socio-economic development initiatives and constraints. My work provides a conceptual overview of globalizing management since Moroccan independence in 1956. Then, a spatially sensitive political economic lens is employed to analyze new urban managerial transformations emerging since 1983 adjustments. Finally, I take an in-depth case study of Tangier City Center project to question how Tangier?s current globalization effectively responds to both state and local urban social and economic development.

--- / Doctorat en Sciences politiques et sociales / info:eu-repo/semantics/nonPublished

Public administration literature lacks richness and context regarding the moral history of the founding of the field in the early 1900s. As a result, current calls for "recapturing the soul" of public administration have failed to stimulate a theory-or even a working understanding-of how to "rehydrate" the observed desiccation of public life and revivify the concept of the public interest. In correcting the historical record, this dissertation shows that the "soul" of public administration stemmed from the field's deep roots in the social gospel movement of the early 20th century. For that short period, the nascent field was not viewed as a bastardization of constitutional order, but as a noble endeavor in which beloved sons and daughters participated in their nation's governance. As a representative character of that era, Charles M. Sheldon serves as an exemplar of a citizen administrator whose sojourn into the public square was characterized by deep faith, empathy for the common person and commitment to action-regardless of the personal cost. His optimism, innovation and creativity stand in sharp relief to today's dispirited and over-regulated public work force. Sheldon's best-selling book, In His Steps (1896), stands as a pre-modern parable for moral decision-making in a dynamic and uncertain postmodern environment. In allowing for uncertainty, discourse and experimentation, the book's operative question, "What would Jesus do?" enriches our understanding of normative theory as process. It also offers back the field's lost "soul" in the way of submission, empathy, covenant, grace and hope. / Ph. D.

The ATP-binding cassette (ABC) transporter, ABCA1, plays a pivotal role in reverse cholesterol transport, which is the elimination of excess sterols from peripheral cells and their transport to the liver for elimination. Early studies failed to detect significant ATPase activity, prompting the suggestion that ABCA1 was an ATP-regulated receptor, rather than an active transporter. We have provided evidence that ABCA1 can bind ATP and trap its hydrolysis product, ADP, in the presence of either ortho-vanadate or beryllium fluoride and Mg2+ or Mn2+. We have also shown that both nucleotide-binding domains (NBDs) trap nucleotide comparably, suggesting that ABCA1 is a functional ATPase. In addition, we have shown that ABCA1 can directly transport 25-hydroxycholesterol (25-OHC) in an ATP-dependent manner using a membrane vesicle uptake assay, and can do so when the physiological substrate acceptor apoA-I is replaced with BSA as a non-specific binding protein. Although more than 50 naturally occurring missense mutations and polymorphisms in ABCA1 have been identified in individuals with HDL-C levels within the lowest 5th percentile of the general population, the extent to which many of these mutations affect ABCA1 function is not known and cannot be predicted. Naturally occurring extracellular loop (ECL) mutations W590S and C1477R have both been shown to effectively eliminate the ability to mediate lipid efflux, despite the fact that the W590S mutant protein retains the ability to bind apoA-I. We show that neither mutant can transport nor efflux 25-OHC, whether in the presence of apoA-I or BSA, despite apparently full retention of the ability to bind and trap nucleotide. This suggests that these two ECL mutations inhibit transport by a mechanism that is independent of their effect on apoA-I binding. By introduction of naturally occurring mutations in the NBDs, we show that although some mutations associated with Tangier Disease, such as N935S, essentially eliminate nucleotide trapping and substrate translocation, other polymorphisms such as L1026P and T2073A associated with low HDL-C, appear to be fully functional. Lastly, we observed differences in the behaviour of both wild-type and mutant forms of ABCA1-GFP depending on whether they were expressed in insect or mammalian cell lines. / Thesis (Ph.D, Pathology & Molecular Medicine) -- Queen's University, 2010-02-12 11:14:11.381

Depuis plusieurs années, toutes les études le montrent : la conscience des citoyens face au développement durable et ses enjeux grandit, mais parallèlement ils peinent à l’intégrer concrètement dans leur vie quotidienne. Au centre de cette dichotomie : un socle culturel, des schémas acquis et des repères doivent être profondément modifiés. L’éducation au développement durable va bien au-delà d’une transmission des connaissances sur le concept. Elle porte cette ambition derefonder nos modes de pensée et d’agir en accord avec un moindre impact environnemental et plus de solidarité.Aujourd’hui, le Maroc entreprend un chantier de mise en harmonie de ses structures économiques, politiques et juridiques de manière à s’inscrire dans l’esprit du développement durable imposé par la constitution de 2011. Dans une société en perpétuelle mutation et confrontée à de nombreux défis environnementaux, l’éducation joue un rôle de pilier dans les tendances en matière de « verdissement » de l’éducation. La mise en place de réseaux éducatifs informels est une des clés de collaborations intersectorielles (enseignants, communes, associations, ONG, entreprises) pour élever le taux deréussite des actions de verdissement de l’éducation en dehors de l’école et ce, en apportant la connaissance scientifique, l’expertise en matière d’éducation à l’environnement et en mettant à disposition des outils adéquats testés et validés.Dans les écoles primaires tangéroises, de nombreuses initiatives voient le jour et permettent de façonner une interface favorable entre connaissances et pratiques. Le territoire local, à travers ses ressources, sert aussi d’appui à cette mise en application de l’EEDD.Cependant de nombreux obstacles (formation, programmes, manuels scolaires, représentations, décalage entre l’école et les familles, etc…) sont identifiés dans la mise en oeuvre de l’EEDD au Maroc. Il semble ainsi nécessaire de continuer à améliorer la sensibilisation, l’information et l’éducation des jeunes marocains à la préservation et à la conservation de leurenvironnement et patrimoine. / For several years, all the studies have shown that the citizens’ awareness regarding sustainable development and its issues is increasing. But simultaneously, they have been trouble to integrate it into their daily life. At the heart of thisdichotomy: cultural base, acknowledged patterns and references need to be deeply changed. Environmental education goes beyond a simple transmission of knowledge about the concept of sustainable development. It has the ambition of reconstructing our way of thinking and acting in way to produce lesser environmental impacts and more solidarity.Nowadays, Morocco undertakes a major project to reorganized its economic, political, and legal structures in such a way to reach the sustainable environmental spirit imposed by the 2011 constitution. In a society in constant changes and confronted to a number of environmental challenges, education is a cornerstone of the leanings in terms of greening education. The setting up of educational and informal networks is one of the keys to the cross-sectoral collaborations (teachers, municipalities, associations, non-profit organizations, companies) to raise the success rate of educationalgreening actions outside of school by providing scientific knowledge, expertise regarding environmental education,and by providing available and suitable tested and validated tools.In the primary schools of Tangier, numerous initiatives are set up in the purpose to implement a favourable interfacebetween knowledge and practice. The local territory, through its resources, serves also as a support to the enforcement of the EEDD.Yet, a lot of obstacles (training, programs, textbooks, representations, gap between the school and families, etc...) are listed for an effective implementation of the EEDD in Morocco. It will be necessary to keep improving the awareness, information, and education of young Moroccans regarding the preservation and protection of their environment and assets.

In my thesis, I argue that Barbara Adair's In Tangier We Killed the Blue Parrot can be viewed as a palimpsest. In this sense her re-inscription of the lives and fictions of lane and Paul Bowles in the International Zone of Tangier, Morocco, in the 1940s reflects on and is implicated in the contemporary South African Zeitgeist. Through illuminating the spatial and temporal connections between the literary text and the social text, I suggest that Adair's novel creates a space for the expression of new patterns of intimacy. The Bowleses' open marriage and their same-sex relationships with local Moroccans are complicated by hegemonies of race, class and gender. To illustrate the nature of these vexed intimacies I explore Paul's sadomasochistic relationship with the young hustler, Belquassim, revealing the emancipatory nature of the expatriate's erotic and violent encounter with the Other. Conversely, I suggest the shades of Orientalism and exoticism in this relationship. While Adair is innovative in her representation of the male characters, I argue that she perpetuates racial and gendered stereotypes in her representation of the female characters in the novel. lane is re-inscribed in myths of madness and selfdestruction, while her lover, Cherifa, vilified and unknowable, is depicted as a wicked witch. This study interrogates the process of selection and representation chosen by Adair, which proceeds from her own intentionality and positionality, as a South African, as a human rights law lecturer, as a (white) woman and as a woman writer. These explorations reveal the liberatory re-imagining of new patterns of intimacy, as well as the limitations of being bound by the implicit racial and gendered divisions of contemporary South African society. / http://hdl.handle.net/10413/1286 / Thesis (M.A.)-University of KwaZulu-Natal, Pietermaritzburg, 2006.