Universiẗat, Diss, 2002--Paderborn.

Thesis (D. Ed. Min.)--New Orleans Baptist Theological Seminary, 2004. / Includes abstract and vita. Includes bibliographical references (leaves 172-176).

Ce travail de thèse s’inscrit dans le projet logistique de l’Assistance Publique Hôpitaux de Marseille. En effet l’AP-HM a ouvert une plateforme logistique en avril 2013 afin de centraliser les activités de production de repas, de stérilisation, de stockage de produits hôteliers et de blanchiment de linge. Ces produits finis sont ensuite transportés dans des contenants, grâce à une équipe de transport, vers les quatre centres hospitaliers de Marseille. Le but de cette étude de recherche est de proposer une méthode et un outil permettant d’aider l’équipe de régulation des transports pour la gestion des ressources de transport. Cette étude prend en compte la variabilité des temps de trans- port ainsi que les aléas pouvant intervenir dans le cycle de vie d’une tournée de transport.Pour cela nous commençons par réaliser un modèle de connaissance du système logistique existant grâce à la méthodologie ASCI. Nous proposons ensuite une méthode et un outil permettant la génération de planning de tournées quotidien. Cette méthode est une solution ad-hoc qui intègre la résolution d’un problème de charge- ment, la planification de véhicules et d’équipages, ainsi qu’une représentation et une mo- délisation statistique de la variabilité des temps de transports en milieu urbain. En effet, le taux de congestion quotidien peut faire varier un temps de transport du simple au double. Enfin pour la gestion des aléas, nous proposons une méthode de réparation de planning que nous modélisons grâce aux systèmes multi agents. Ce dernier point de ce travail de thèse permet, en fonction des scénarios de défaillance, de proposer la solution la plus adaptée aux équipes de transport. / This thesis work is part of the logistics project of the Assistance Publique-Hôpitaux de Marseille. Indeed the AP-HM opened a logistics platform in April 2013 in order to central- ize production activities of meals, sterilization, storage product and bleaching of linen. These products are then transported in containers, thanks to a team of transport, to the four hospitals in Marseille. After consumption of the products, by healthcare units, used containers must be re- ported to the logistics platform that they are disinfected and reinstated in the production loop. The purpose of this research study is to propose a method and a tool to help the team of regulation of transport for the management of transport resources. This study takes into account the variability of the transport time and the hazards that could inter- vene in the life cycle of a tour of transport.For this we make a knowledge model of logistics system using the ASCI methodology. This model of knowledge is then validated with a simulation model. We offer then a method and a tool allowing the generation of daily tour schedule. This method is an ad - hoc solu- tion that integrates solving a problem loading, planning for vehicle and crew, as well as representation and statistical modelling of variability in the time of transport in urban areas. Indeed, the daily congestion rate can vary a transport time of one to two. Finally, for the management of the ups and downs, we propose a method of repair of planning that we model with multi agent systems. This last point of this thesis according to failure sce- narios, makes it possible to propose the best solution to the transport staff.

The thesis is focused on the theme of mushrooms and their importance in nutrition. The theoretical part deals with the chemical composition of higher mushrooms in general and describes their significance for human health. It focuses mainly on the positive effects of mushrooms on the human body. The practical part consists of questionnaires on the subject and their evaluation. The aim of my work was to find out what knowledge about mushrooms people have and how often they consume them.

Dissertação (mestrado)—Universidade de Brasília, Faculdade de Medicina, Programa de Pós-Graduação em Ciências Médicas, 2017. / Submitted by Raquel Almeida (raquel.df13@gmail.com) on 2017-12-11T19:19:05Z No. of bitstreams: 1 2017_SimoneRiosFonsecaRitter.pdf: 999026 bytes, checksum: efd6e9f2165ae4457741501006972717 (MD5) / Approved for entry into archive by Raquel Viana (raquelviana@bce.unb.br) on 2018-02-15T18:44:38Z (GMT) No. of bitstreams: 1 2017_SimoneRiosFonsecaRitter.pdf: 999026 bytes, checksum: efd6e9f2165ae4457741501006972717 (MD5) / Made available in DSpace on 2018-02-15T18:44:38Z (GMT). No. of bitstreams: 1 2017_SimoneRiosFonsecaRitter.pdf: 999026 bytes, checksum: efd6e9f2165ae4457741501006972717 (MD5) Previous issue date: 2018-02-15 / Introdução: O delirium é uma das síndromes mais frequentes no idoso admitido em uma unidade de emergência, caracterizado por início súbito com flutuações durante o dia; alteração do nível de consciência; perturbação global da cognição ou anormalidades perceptuais e comportamentais e é frequentemente não diagnosticado. Objetivos: Estimar prevalência de delirium em serviço de urgência e avaliar fatores associados, a acurácia diagnóstica do médico plantonista e adaptar o Abbreviated Mental Test Score (AMT) como teste de rastreio para delirium em idosos admitidos em uma unidade de urgência. Métodos: Estudo transversal realizado em serviço de urgência do Hospital Universitário de Brasília, de abril a junho/2014. Foi utilizado como parâmetro para o critério de delirium o Confusion Assessment Method Instrument (CAM). Foi coletado em prontuário dado de suspeita diagnóstica pelo médico plantonista. Adicionalmente, foram analisadas variáveis sociodemográficas, psicocomportamentais e fatores clínicos e realizadas análises multivariadas de modelos aditivos, utilizando-se o Epi Info 7.1.3.0. Foram aplicadas questões do AMT em versão traduzida e adaptada culturalmente, com quatro modelos distintos, mais modelos reduzidos, todos comparados ao CAM a partir da curva ROC (significância < 0,05; H0: ACS = 0,5) e a reprodutibilidade inter-avaliadores a partir do Índice Kappa, utilizando-se SPSS. Resultados: Amostra final de 110 participantes com média etária de 72,2 + 8,3 anos, sendo 56,4% homens e uma prevalência de delirium de 28,2%. Fatores associados significativamente ao delirium: sexo masculino (valor-p = 0,019), percepção da saúde como ruim ou muito ruim (valor-p = 0,033), demência prévia (valor-p < 0,001), história prévia de acidente vascular cerebral (valor-p = 0,014) e infecção bacteriana aguda (valor-p = 0,008). Médicos assistentes apresentaram taxa de 64,5% de não diagnóstico, com sensibilidade de 35,5%, especificidade de 100% e acurácia de 81,8%. O melhor dos quatro modelos completos do AMT, em amostra de 90 pacientes, apresentou sensibilidade de 78,3% e especificidade de 85,1%, com boa reprodutibilidade inter-avaliador (Kappa = 0,793). O melhor modelo reduzido foi de quatro itens, com sensibilidade de 82,6% e especificidade de 82,1% com Kappa de 0,746. Conclusões: A prevalência de delirium foi concordante com a literatura, mas ainda pouco diagnosticado no serviço estudado. A adaptação do AMT (completa e reduzida) mostrou-se adequada como alternativa para o rastreio rápido de delirium em idosos admitidos em urgência, quando comparada ao padrão ouro, principalmente para pacientes desacompanhados e sem déficit cognitivo prévio. / Introduction: Delirium is one of the most frequent syndromes in the elderly admitted in emergency unit, characterized by sudden onset with fluctuations during the day; alteration of the level of consciousness; cognitive impairment or perceptual and behavioral abnormalities and is often undiagnosed. Objectives: To estimate the prevalence of delirium in the emergency department and evaluate associated factors, the diagnostic accuracy of the attending physician and to adapt the Abbreviated Mental Test Score (AMT) as a screening test for delirium in elderly admitted to an emergency unit. Methods: A cross-sectional study carried out in the emergency department of the Hospital Universitário de Brasília from April to June/2014. The Confusion Assessment Method Instrument (CAM) was used as a parameter for delirium criteria. Data of suspected diagnosis by the attending physician was collected in medical records. In addition, sociodemographic, psycho-behavioral variables and clinical factors were analyzed, and multivariate analyzes of additive models were performed using Epi Info 7.1.3.0. We applied AMT questions in a translated and culturally adapted version, with four different models, more reduced models, all compared to CAM from the ROC curve (significance <0.05; H0: AUC = 0.5) and inter-evaluators reproducibility from the Kappa Index using SPSS. Results: Final sample of 110 participants with mean age of 72.2 + 8.3 years, 56.4% of men and a prevalence of delirium of 28.2%. Factors significantly associated with delirium: male sex (p-value = 0.019), poor or very poor health perception (p-value = 0.033), previous dementia (p-value <0.001), previous history of stroke (p-value = 0.014) and acute bacterial infection (p-value = 0.008). Physicians assistants had a non-diagnostic rate of 64.5%, with sensitivity of 35.5%, specificity of 100% and accuracy of 81.8%. The best of the four complete AMT models, in a sample of 90 patients, presented sensitivity of 78.3% and specificity of 85.1%, with good inter-rater reproducibility (Kappa = 0.793). The best reduced model was of four items, with sensitivity of 82.6%, specificity of 82.1% and Kappa = 0.746. Conclusions: The prevalence of delirium was consistent with the literature, but still little diagnosed in the service studied. AMT adaptation (complete and reduced) was adequate as an alternative for the rapid screening of delirium in elderly admitted in emergency, when compared to the gold standard, mainly for unaccompanied patients and without previous cognitive deficit.

Dissertação (mestrado)—Universidade de Brasília, Faculdade de Ceilândia, Programa de Pós-Graduação em Ciências e Tecnologias em Saúde, 2017. / Texto parcialmente liberado pelo autor. Conteúdo liberado: Resumo e Abstract. / Submitted by Raquel Almeida (raquel.df13@gmail.com) on 2018-03-14T18:54:41Z No. of bitstreams: 1 LusmairMartinsdeBrito_PARCIAL.pdf: 916174 bytes, checksum: dae3c9960e6f4ba8e033c9141a8f4109 (MD5) / Approved for entry into archive by Raquel Viana (raquelviana@bce.unb.br) on 2018-04-09T20:14:31Z (GMT) No. of bitstreams: 1 LusmairMartinsdeBrito_PARCIAL.pdf: 916174 bytes, checksum: dae3c9960e6f4ba8e033c9141a8f4109 (MD5) / Made available in DSpace on 2018-04-09T20:14:31Z (GMT). No. of bitstreams: 1 LusmairMartinsdeBrito_PARCIAL.pdf: 916174 bytes, checksum: dae3c9960e6f4ba8e033c9141a8f4109 (MD5) Previous issue date: 2018-04-09 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES). / Introdução: A satisfação profissional tem sido estudada e avaliada por sua influência no comportamento organizacional das instituições, assim como pelas repercussões na vida pessoal do trabalhador, na sua saúde física e mental, nas atitudes, no comportamento profissional e social. Objetivo: Analisar a satisfação e insatisfação no trabalho de profissionais do Hospital Universitário de Brasília. Metodologia: Trata-se de um estudo descritivo com abordagem qualitativa, realizado com 52 profissionais da clínica cirúrgica e do centro de pronto atendimento do HUB, no período de fevereiro a dezembro de 2016. A coleta de dados foi através de entrevista individual semi-estruturada. Os dados foram sistematizados no software Atlas.Ti e analisados em 7 categorias (o hospital como espaço de formação e trabalho; condições do emprego; condições de trabalho; composição e divisão do trabalho; relações no trabalho; percepções sobre o modo de trabalhar e trabalho assistencial). Resultados: Quanto a caracterização do perfil dos participantes houve predominância do sexo feminino; a faixa etária que prevaleceu entre os profissionais foi de 30 a 39 anos; o nível de escolaridade que sobressaiu foi a especialização; sendo o maior número dos entrevistados técnicos de enfermagem; a carga horária da maior parte do profissionais era de 30 horas semanais; a maioria trabalhava no turno diurno; o vínculo prevalente foi da EBSERH; metade dos profissionais entrevistados só trabalhavam no HUB e possuíam até um ano de trabalho na instituição e de tempo de serviço. Os principais elementos de satisfação e insatisfação no trabalho foram trabalho em equipe e a relação entre os profissionais. Prevaleceu como motivo de satisfação dos profissionais trabalhar com o que gosta. A principal causa de insatisfação foi a demora e a burocracia no sentido de criar restrições, dificultar a entrega de material ou a prestação de algum serviço aos setores e usuários. Considerações finais: Os achados demonstraram a existência de diferentes vínculos na instituição, falta de material e profissionais, falta de planejamento e desorganização com a estrutura e o processo de trabalho, sendo necessário uma reflexão acerca da gestão dos setores e do hospital, afim de superar as dificuldades nas condições e relações de trabalho. No entanto, apesar de todos os problemas e fatores de insatisfação com o trabalho em um hospital universitário, também verificamos que a oportunidade do profissional estar em constante aprendizado e principalmente gostar do que faz ou da profissão influencia na satisfação com o trabalho. / Introduction: The professional satisfaction has been studied and evaluated due to its influence in the organizational behavior of the institutions, as well as by the repercussions in the personal life of the worker, in his physical and mental health, in his attitudes and in his professional and social behavior. Objective: It is to analyze the satisfaction and the dissatisfaction in the professionals workplace at the Hospital Universitário de Brasília. Methodology: It is a descriptive study with qualitative approach, accomplished with 52 professionals of the surgical clinic and of the emergency care center of HUB, from february to december 2016. The data collection was through a semi-structured individual interview. The data were systematized in the software Atlas.Ti and analyzed in 7 categories (the hospital as a space for training and work; employment conditions; work conditions; composition and division of labor, relashionships at work; perceptions about the way of working and care work). Results: Regarding the characterization of the participant’s profile, there was a predominance of the female gender; the age group that prevailed among professionals was 30 to 39 years; the educational level emerged was the specialization, being the largest number of the interviewed nursing technicians; the workload of most professionals was 30 hours a week; the most of them used to work day shift; the prevalent link was the EBSERH; half of the interviewed professionals only worked in HUB and had up to one year of work in the institution and time of service. The main elements of job satisfaction and dissetisfaction were teamwork and the relationships between professionals. It has prevailed as a reason for the professionals satisfaction to work with what they like. The main cause of dissetisfaction was the delay and bureaucracy in order to create restrictions, to make it difficult to deliver of materials or the provision of some service to sectors and users. Final considerations: The finding demonstrated the existence of different links in the institution, lack of material and professionals, lack of planning and disorganization of the work structure and work process, requiring a reflection on the management of the sectors and the hospital, in order to overcome the difficulties in the working conditions and relations. However, despite all the problems and factors of dissatisfaction in a university hospital, we also found that the opportunity for the professional to be in constant learning and specially to enjoy what he does or his profession, influence job satisfaction.

Dissertação (mestrado)—Universidade de Brasília, Núcleo de Medicina Tropical, Pós-Graduação em Medicina Tropical, 2014. / Submitted by Ana Cristina Barbosa da Silva (annabds@hotmail.com) on 2015-03-02T19:22:47Z No. of bitstreams: 1 2014_LeandroCorreaMachado_Parcial.pdf: 467097 bytes, checksum: 023f25aec34a8da04331f9948e40450a (MD5) / Approved for entry into archive by Raquel Viana(raquelviana@bce.unb.br) on 2015-03-20T17:31:39Z (GMT) No. of bitstreams: 1 2014_LeandroCorreaMachado_Parcial.pdf: 467097 bytes, checksum: 023f25aec34a8da04331f9948e40450a (MD5) / Made available in DSpace on 2015-03-20T17:31:39Z (GMT). No. of bitstreams: 1 2014_LeandroCorreaMachado_Parcial.pdf: 467097 bytes, checksum: 023f25aec34a8da04331f9948e40450a (MD5) / A transmissão da leishmaniose visceral (LV) tem sido descrita em várias regiões do Brasil. Progressivamente, tem sido observada a urbanização da doença, associada ao processo migratório para as cidades de médio e grande porte, sendo evidente a concentração dos casos nesses centros urbanos. A letalidade pela LV nos últimos anos vem aumentando gradativamente, principalmente em pessoas vivendo com HIV/AIDS. . Nesses pacientes, a LV apresenta pior prognóstico caracterizado por recidivas frequentes e maior letalidade. Ao mesmo tempo, o número de relatos de reativação de LV em pessoas submetidas à imunossupressão para fins terapêuticos tem aumentado. O presente estudo descritivo transversal foi desenvolvido em amostra de conveniência com o objetivo principal de estimar a prevalência da infecção assintomática por Leishmania spp. e pacientes imunodeficientes do Hospital Universitário de Brasília. Foram avaliados 146 pacientes divididos em três grupos: pessoas vivendo com HIV/AIDS (48 participantes); imunossuprimidospelo tratamento de doenças reumáticas (47 participantes) e; pacientes submetidos a transplante renal (51 participantes). Amostras de sangue obtidas dos participantes foram submetidas à detecção de DNA do parasito por meio da PCR- ITS1 e detecção de anticorpos específicos anti- Leishmania por meio dos testes de aglutinação direta DAT, imunofluorescência indireta IFAT e o teste imunocromatográfico rápido baseado no antígeno recombinante rK39. Foi encontrada uma positividade empelo menos um dos testes em 23 dos 146 pacientes, sendo estimada uma prevalência de 17,2% (IC95% 11,6 a 24,4). Vinte e dois participantes apresentaram positividade no teste ELISA-rK39 (15,0%); cinco (3,4%) participantes apresentaram positividade no DAT; um participante apresentou positividade no teste rápido ICT-rK39 (0,6%) e um participante (0,6%) teve resultado positivo no teste de imunofluorescência indireta. Nenhuma amostra teve resultado positivo na PCRITS1 e em todas as amostras foi possível amplificar o gene de actina humana. A concordância bruta entre os testes foi baixa e os resultados sugerem a necessidade de uso combinado de múltiplos testes para melhorar a capacidade de detecção da infecção assintomática por Leishmania spp. Na população com déficit de imunidade. / The propagation of visceral leishmaniasis (VL) has been described in many regions of Brazil. Gradually, the urbanization of the disease has been observed, associated to the migration process of people to cities of medium and large size, the concentration of many cases being evident in those urban centers. The lethality of VL in recent years has increased gradually, mostly in people with HIV/AIDS. In these patients, VL has a worse prognosis which is characterized by frequent relapses and increased mortality. At the same time, the number of reports of reactivation of VL in people submitted to immunosuppression for therapeutic purposes has increased. This cross-sectional study was conducted in a sample of convenience with the main objective of estimating the prevalence of asymptomatic infection with Leishmania spp. and immunodeficient patients treated at the University Hospital of Brasília. This study evaluated 146 patients divided into three groups: people living with HIV/AIDS (48 participants), those immunosuppressed by treatment of rheumatic diseases (47 participants), and patients undergoing kidney transplant (51 participants). Blood samples taken from the participants were subjected to the detection of parasite DNA by PCRITS1 and detection of specific anti-Leishmania antibodies through direct agglutination test (DAT), indirect immunofluorescence (IFAT), the rapid test based on rK39 antigen (ICT-rK39 test) and the immunoassay based on recombinant antigen rK39 (ELISA-rK39). Positivity was found in at least one of those tests in 23 of 146 patients, an estimated prevalence of 17.2% (IC 95% 11.6 a 24.4). Twenty-two participants tested positive on ELISA-rK39 (15,0%); five (3.4%) participants tested positive on DAT; one participant was positive on ICT-rK39 (0.6%) and one participant (0.6%) was positive on IFAT. No sample tested positive on PCR-ITS1 and in all samples it was possible to amplify the gene of human actin. The crude agreement between tests was low and the results suggest the need for combined use of multiple tests to improve the capacity to detect asymptomatic infection by Leishmania spp. in the immunodeficientpopulation.

The Internet of Things (IoT) is rapidly gaining ground in our daily life. There is a trend that the number of devices and data increases rapidly in the future. Meanwhile, IoT platforms are emerging to enable people conveniently deal with the IoT and these huge amount of data and devices. Therefore, the goal in this paper is to perform a quantitative evaluation on Microsoft Azure, one of the IoT platform, about its advantages and disadvantages under press to determine if Azure IoT is fit for future IoT. In order to reach this goal, Azure IoT Hub is used as a bridge to connect and manage lots of IoT devices which send and receive huge amount of data. .NET is used to simulate devices and connect them to the IoT Hub. The two-way communication from sensor to cloud and from cloud to actuator is implemented through MQTT protocol. This paper makes measurements on three metrics including response time from sensor sending messages to actuator receiving messages, scalability and cost and analyzes them in detail. Besides, the analysis is also made in a specific scenario which has high demand on sensor update to see how Azure IoT performs. Finally, conclusion is made on Microsoft Azure IoT's advantages and disadvantages under stress.

The concept of innovation hubs are increasingly being adopted by different sectors as a means to accelerate innovation. Previous research on innovation hubs have focused on large-scale and trans-regional hubs on its managerial practices instead of its geographical situation. This paper studies an innovation hub in the Northern Swedish city of Skellefteå, in a region historically relying on heavy industry trying to transform into a high technology economy. The study aims to answer the research question: “what are the challenges and opportunities in building and managing an innovation hub to foster innovation in a geographically isolated region with a relatively small population?” To answer this question, interviews with stakeholders in the innovation hub has been conducted as part of a qualitative case study. The results indicate that the region’s large heavy industry companies provide a fertile ecosystem for startups in the digital industry by enabling the necessary supporting industries and infrastructure. Meanwhile, the lack of certain important elements needed in the startup process, most prominently private funding in the form of angel investors and venture capital, pose challenges to the development of the digital startup community in the region.

Dissertation thesis Air Cargo HUBs and Corridors deals with air cargo transport and HUB and Spoke technology and it is focused on Václav Havel Airport Prague. The purpose of this disseration thesis is to present air cargo transport with all its specifics, to explain application of HUB and Spoke technology in air cargo transport and location of the most important air cargo HUBs. This thesis searches for an answer to a question whether Václav Havel Airport Prague can be considered an air cargo HUB. To meet the target methods of research, analysis, description and comparasion were used. On the basis of assessment of current situation, nowadyas it is not possible to consider Václav Havel Airport Prague an air cargo HUB. An entrance of a new air cargo carrier, a reinforcement of current connections and the construction of parallel runway indicate an increase in transported air cargo, depending on positive economic development.