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O polo aquático (PA) é um esporte coletivo e de invasão praticado no meio líquido. Dentre as técnicas utilizadas pelos jogadores de PA, destaca-se o eggbeater (EB), movimento propulsivo de membros inferiores que permite ao jogador a permanência na posição vertical e deslocamentos. Devido às especificidades do gesto de EB e à falta de informações a respeito das características fisiológicas de jogadores de PA, o objetivo deste estudo foi comparar e verificar a concordância de resultados obtidos de testes de esforço máximo realizados dentro (com EB) e fora da água (em cicloergômetro). Para tal, doze jogadores de PA (30,5 ± 7,7 anos de idade; 79,2 ± 7,2 kg de massa corporal; 179,1 ± 5,9 cm de estatura) foram avaliados em duas etapas: (1) em laboratório com teste máximo em ciclo-ergômetro e (2) em piscina com teste máximo em EB. Em ambas as etapas foram obtidos: consumo máximo de oxigênio (VO2max), taxa de troca gasosa (RER), frequência cardíaca máxima (FCmax) e esforço percebido (EP). Entre os dados obtidos de ambos os testes foram realizadas análises descritivas, análises de comparação, correlação intra-classe e concordância. Não foram encontradas diferenças entre os valores máximos obtidos nos dois testes (ciclo-ergômetro: VO2max = 40,2 ± 2,7 ml.kg-1.min-1, RER = 1,17 ± 0,08, FCmax = 181,4 ± 11,7 bpm; EP = 20; eggbeater: VO2max = 38,4 ± 5,7 ml.kg- 1.min-1, RER = 1,19 ± ,12, FCmax = 179 ± 11,7 bpm; EP = 20). De modo geral, os valores encontrados no teste em EB apresentaram maior variabilidade, porém análises de Bland-Altmann indicam limites de concordância aceitáveis para VO2max, RER e FCmax obtidos de diferentes métodos (dentro e fora da água) entre jogadores de PA. / Water polo (PA) is a team and invasion sport performed in water. Among the techniques used by the players, the eggbeater kick (EB) is a propulsive movement of the lower limbs, which allows the player to remain in the upright position and to displace. Due to the specifics of the EB and the lack of information about the physiological characteristics of PA players, the aim of this study was to compare and to verify the agreement of maximal exercise tests in (EB) and out (cycling) water. Twelve PA players (30.5 ± 7.7 years, 79.2 ± 7.2 kg body mass; 179.1 ± 5.9 cm height) were evaluated in two steps: (1) in laboratory with maximal test on a cycle ergometer and (2) in pool with maximum test in EB. In both phases, maximal oxygen uptake (VO2max), gas exchange ratio (RER), maximal heart rate (HRmax) and perceived exertion (EP) were obtained. The descriptive analysis, comparison analysis, intra-class correlation and level of agreement were performed. No differences were found between the maximum values obtained in the two tests (cycle ergometer: VO2max = 40.2 ± 2.7 ml.kg-1.min-1, RER = 1.17 ± 0.08, FCmax = 181.4 ± 11.7 bpm; EP = 20; eggbeater: VO2max = 38.4 ± 5.7 ml.kg-1.min-1, RER = 1.19 ± 12 water, FCmax = 179 ± 11.7 bpm; EP = 20). In general, the values in EB test showed greater variability than in cycle ergometer, but the Bland-Altmann analyzes indicate acceptable limits of agreement for VO2max, RER and HRmax obtained from different methods (in and out water) in PA players.

Use of Nano Zero Valent Iron (nZVI) for treatment of different halogenated hydrocarbons, arsenic and various other contaminants has been proved successful. However, with so much diversified use of nZVI in the field and heighted attention to engineered nanoparticles, the environmental fate and impact of the nZVI remains unknown. The goal of this project was to evaluate the effects of different types of nZVI on Typha latifolia, a common wetland plant and hybrid poplar (Populous deltoids x Populous nigra), a woody plant used in phytoremediation. Plants grown hydroponically in a green house were dosed with different concentration of bare or bimetallic nZVI (with 10% nickel coating) for one to four weeks. The results showed that bare nZVI had toxic effects to Typha in higher concentrations but enhanced growth of plants at lower concentrations. Bare nZVI did not significantly affect the growth of poplars but bimetallic nZVI did impede the growth. Bimetallic nano particles were significantly more toxic and resulted in death of Typha within a week of dosing. Scanning electron microscope (SEM) clearly showed the adsorption of the nZVI on the plant root surface, confirmed by Energy dispersive x-ray (EDX) analysis. Transmission electron microscope (TEM) and Scanning Transmission electron microscope (STEM) confirmed the uptake of nZVI by poplar plant, but such internalization was not observed in case of Typha. However, uptake of the nanoparticles was only limited to the root and the translocation of particles to the shoot was not observed.

Submitted by Sayuri Beatriz Hara Noda (sbhnoda@gmail.com) on 2018-11-05T17:47:50Z No. of bitstreams: 2 Dissertação DEFINITIVO final.pdf: 1530086 bytes, checksum: 8dadcadd3651508d8270007afac1647a (MD5) Dissertação DEFINITIVO final.docx: 2167242 bytes, checksum: 514929fb7b5ba6abd6001d8f5ca41ed6 (MD5) / Approved for entry into archive by Maria Lucia Martins Frederico null (mlucia@fca.unesp.br) on 2018-11-06T16:09:03Z (GMT) No. of bitstreams: 1 noda_sbh_me_botfca.pdf: 1530086 bytes, checksum: 8dadcadd3651508d8270007afac1647a (MD5) / Made available in DSpace on 2018-11-06T16:09:04Z (GMT). No. of bitstreams: 1 noda_sbh_me_botfca.pdf: 1530086 bytes, checksum: 8dadcadd3651508d8270007afac1647a (MD5) Previous issue date: 2018-08-07 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / As curvas de absorção de nutrientes e o acúmulo de matéria seca em função da idade da planta possibilitam conhecer os períodos de maior exigência dos nutrientes e de produção de massa de matéria seca, obtendo-se informações seguras quanto às épocas mais convenientes de aplicação de fertilizantes. Frequentemente, empresas privadas, empresas públicas e cooperativas estão desenvolvendo novos híbridos e cultivares de cebola adaptadas às variadas condições climáticas, com diferentes exigências nutricionais. Desse modo, são necessários estudos envolvendo as curvas de absorção de nutrientes dos diversos genótipos lançados, no sentido de aprimorar as recomendações de calagem e adubação. O objetivo do projeto foi obter a curva de absorção de nutrientes em híbridos de cebola em condições de campo. O projeto foi desenvolvido em parceria com a empresa Sakata Seed Sudamerica Ltda que forneceu o material utilizado para o experimento. As plantas amostradas periodicamente foram analisadas para os teores de macro e micronutrientes seguindo metodologia descrita na literatura. Os resultados dos teores de nutrientes foram multiplicados pela massa seca da parte aérea, bulbos e raízes, para gerar a quantidade de nutrientes contida nas plantas de cebola e assim, poder gerar a curva de absorção. Além disso, os bulbos colhidos foram analisados quanto às características físicas e químicas para fins de caracterização do material. De modo geral ambos os materiais se comportaram de modo semelhante quanto ao acúmulo de nutrientes. A quantidade de extração apresentaram dados relevantes para o manejo da adubação dos híbridos estudados. As quantidades exportadas demonstraram que ambos os materiais foram eficientes na conversão de nutrientes para formação de bulbos. / The absorption march of nutrients and the accumulation of dry matter through plant’s growth stages provide information about periods of highest nutrient demand and dry mass production, obtaining reliable data on the most advantageous moment of application of fertilizers. Often, private companies, public companies and co-ops develop new onion hybrids and cultivars adapted to varied climate conditions with different nutritional requirements. Thus, researches about the nutrients absorption march of different cultivars are essential, in order to improve the liming and fertilization recommendations and to increase the onion yield. The purpose of this study was to determine the growth and nutrients uptake by two different onion hybrid plants under field conditions. The project was developed in partnership with the company Sakata Seed Sudamerica Ltda that provided the material used in the experiment and location. The plants collected were analyzed for macronutrients and micronutrients contents according to methodology described in literature. The analyses were done by the University’s laboratory. The results of the analyses were multiplied by the dry matter of leaves, bulbs and roots, in order to obtain the amount of nutrients in the onion plants. Further, the harvested bulbs were analyzed for physical and chemical characteristics to characterization purposes. In general, both genotypes behaved similarly to nutrient accumulation. The amount of extraction presented relevant data for the management of the fertilization of the studied hybrids. The exported quantities showed that both materials were efficient in converting nutrients to bulb formation / Código de Financiamento 001

O polo aquático (PA) é um esporte coletivo e de invasão praticado no meio líquido. Dentre as técnicas utilizadas pelos jogadores de PA, destaca-se o eggbeater (EB), movimento propulsivo de membros inferiores que permite ao jogador a permanência na posição vertical e deslocamentos. Devido às especificidades do gesto de EB e à falta de informações a respeito das características fisiológicas de jogadores de PA, o objetivo deste estudo foi comparar e verificar a concordância de resultados obtidos de testes de esforço máximo realizados dentro (com EB) e fora da água (em cicloergômetro). Para tal, doze jogadores de PA (30,5 ± 7,7 anos de idade; 79,2 ± 7,2 kg de massa corporal; 179,1 ± 5,9 cm de estatura) foram avaliados em duas etapas: (1) em laboratório com teste máximo em ciclo-ergômetro e (2) em piscina com teste máximo em EB. Em ambas as etapas foram obtidos: consumo máximo de oxigênio (VO2max), taxa de troca gasosa (RER), frequência cardíaca máxima (FCmax) e esforço percebido (EP). Entre os dados obtidos de ambos os testes foram realizadas análises descritivas, análises de comparação, correlação intra-classe e concordância. Não foram encontradas diferenças entre os valores máximos obtidos nos dois testes (ciclo-ergômetro: VO2max = 40,2 ± 2,7 ml.kg-1.min-1, RER = 1,17 ± 0,08, FCmax = 181,4 ± 11,7 bpm; EP = 20; eggbeater: VO2max = 38,4 ± 5,7 ml.kg- 1.min-1, RER = 1,19 ± ,12, FCmax = 179 ± 11,7 bpm; EP = 20). De modo geral, os valores encontrados no teste em EB apresentaram maior variabilidade, porém análises de Bland-Altmann indicam limites de concordância aceitáveis para VO2max, RER e FCmax obtidos de diferentes métodos (dentro e fora da água) entre jogadores de PA. / Water polo (PA) is a team and invasion sport performed in water. Among the techniques used by the players, the eggbeater kick (EB) is a propulsive movement of the lower limbs, which allows the player to remain in the upright position and to displace. Due to the specifics of the EB and the lack of information about the physiological characteristics of PA players, the aim of this study was to compare and to verify the agreement of maximal exercise tests in (EB) and out (cycling) water. Twelve PA players (30.5 ± 7.7 years, 79.2 ± 7.2 kg body mass; 179.1 ± 5.9 cm height) were evaluated in two steps: (1) in laboratory with maximal test on a cycle ergometer and (2) in pool with maximum test in EB. In both phases, maximal oxygen uptake (VO2max), gas exchange ratio (RER), maximal heart rate (HRmax) and perceived exertion (EP) were obtained. The descriptive analysis, comparison analysis, intra-class correlation and level of agreement were performed. No differences were found between the maximum values obtained in the two tests (cycle ergometer: VO2max = 40.2 ± 2.7 ml.kg-1.min-1, RER = 1.17 ± 0.08, FCmax = 181.4 ± 11.7 bpm; EP = 20; eggbeater: VO2max = 38.4 ± 5.7 ml.kg-1.min-1, RER = 1.19 ± 12 water, FCmax = 179 ± 11.7 bpm; EP = 20). In general, the values in EB test showed greater variability than in cycle ergometer, but the Bland-Altmann analyzes indicate acceptable limits of agreement for VO2max, RER and HRmax obtained from different methods (in and out water) in PA players.

Background: An ageing society and rising prevalence in dementia are associated with rising demand for care home places. Monitoring technologies (e.g. bed-exit alarms; wearable location-tracking devices) are appealing because of their potential to enhance safety, increase resident freedom, and reduce staff burden. However, it is unclear how far use of such technologies can deliver potential benefits, and there are ethical challenges from their use. This study explored the implementation of monitoring technologies in care homes for people with dementia, to identify facilitators and barriers to the implementation of these technologies in practice. Methods: An embedded multiple-case study design was employed with 3 dementia-specialist care homes in North-West England. Data collection included 36 semi-structured interviews with staff, relatives and residents, informed by Normalization Process Theory to focus on individual and organisational factors within implementation; 175 hours’ non-participant observation; investigation of care records and technology manufacturer literature; and questionnaires to establish participant attitudes towards technologies. Qualitative data were analysed using Framework Analysis. Findings: 5 overarching themes emerged: (1) Reasons for using technologies; (2) How technologies were implemented; (3) What happened when using technologies; (4) Understanding of technologies; (5) Business and environmental influences. Mitigation of risk seemed to override other potential benefits (e.g. resident freedom) or ethical concerns (e.g. the remote monitoring of residents with impaired cognition), as a reason for use. This emphasis seemed to position monitoring technologies as being understood as fundamentally different to other interventions, and challenged adherence to philosophies of care emphasising resident choice. Some staff, relatives and residents did not seem to be involved in discussion and decision-making regarding technologies, and seemed to lack knowledge about technologies within the homes. Staff training appeared mainly informal, based upon assumptions of simplicity of use, which might not have been sufficient to ensure that staff fully understood the technologies. Staff understanding and awareness of the technologies appeared to be influenced in part by location, both organisationally (i.e. their role) and physically (i.e. within the building). Technical and physical properties of the technologies appeared to work in relation with the physical environments of the homes, which suggested that there may not be an ideal set of physical properties for any particular technology. Some technologies offered a range of functional and information-gathering capabilities, which at times were perceived to be useful complements to practice, but at other times less useful, particularly if they were imbued with a financial cost that was not justifiable from a business perspective. Conclusions: Care homes may need to consider greater involvement of all stakeholders in discussions and decisions regarding the use of monitoring technologies, in order to deepen understandings about the potential benefits and challenges from their use. There is also a need to consider the technical compatibility of technologies with the care home premises, and the financial implications from investing in technologies.

Made available in DSpace on 2014-06-11T19:28:30Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-07-29Bitstream added on 2014-06-13T19:16:29Z : No. of bitstreams: 1 galati_vc_me_jabo.pdf: 170793 bytes, checksum: d0fabeb3194e3b8aa6988a1e309db1f7 (MD5) / Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / O experimento foi realizado de 14 de janeiro a 14 de maio de 2009, na UNESP Câmpus de Jaboticabal, SP, com o objetivo de quantificar o crescimento da planta e o acúmulo de macro e micronutrientes do quiabeiro, no decorrer do ciclo, e obter equações que melhores os representem. A cv. Santa Cruz 47 foi semeada diretamente nos sulcos abertos no solo, colocando-se três sementes a uma profundidade de 3 cm e espaçamento de 1 x 0,2 m. O desbaste foi realizado 15 dias após semeadura (DAS). No decorrer do ciclo, realizaram-se coletas aleatórias de plantas com intervalos de quinze dias. As médias foram ajustadas às equações de regressão polinomial e de parâmetros não lineares. Aos 50 DAS houve um elevado incremento no acúmulo de matéria seca nas partes das plantas. Na colheita final, 120 DAS, as folhas, a haste e os frutos representaram 21; 71 e 8%, respectivamente, da matéria seca total da planta. Na cultura do quiabeiro o acúmulo de macro e micronutrientes foi maior na fase reprodutiva. A sequência decrescente de acúmulo de nutrientes pelo quiabeiro foi K, Ca, N, Mg, P, S, Fe, B, Mn, Zn e Cu, em quantidades equivalentes à 6.002,8; 4.733,8; 2.930,8; 1.196,3; 473,7; 436,2; 49,82; 10,4; 7,1; 7,1 e 1,52 mg planta-1. As quantidades exportadas pela cultura foram 146,5; 23,7; 300,1; 236,7; 59,8 e 21,8 kg ha-1 de N, P, K, Ca, Mg e S, respectivamente, e de 520,0; 76,0; 2.491,0; 355,0 e 355,0 g ha-1 de B, Cu, Fe, Mn e Zn, respectivamente / The experiment was carried out at Jaboticabal, SP, Brazil, from January 14th to May 14th, 2009. The objective of this project was to quantify the okra crop’s growth and macro and micronutrients accumulation during its life-cycle obtaining equations that best represent it. The cv. Santa Cruz 47 was sowed into furrows in the soil, placing three seeds to a depth of about 3 cm arranged in a spacing of 1 x 0,2 m. The cleaning had been done by 15 days after sowing (DAS). During the life-cycle were colected random samples of plants at 15 days intervals. The means were adjusted to polynomial regression equations set of non-linear parameters. At 50 DAS there has been a dry matter increase in plants’ parts. At the final harvest, 120 DAS, the leaves, stems and fruits accounted for 21, 71 and 8%, respectively, from the total plant dry matter. In the okra crop the macro and micronutrients accumulation was higher in the reproductive period. The decreasing sequence of nutrient accumulation was K, Ca, N, Mg, P, Fe, B, Mn, Zn and Cu equivalent to 6,002.8; 4,733.8; 2,930.8; 1,196.3; 473.7; 436.2; 49.8; 10.4; 7.1; 7.1 e 1.5 mg plant-1. The quantity accumulated of culture were 146.5; 23.7; 300.1; 236.7; 59.8 e 21.8 kg ha-1 of N, P, K, Ca, Mg e S, respectively, and 520.0; 76.0; 2,491.0; 355.0 e 355.0 de B, Cu, Fe, Mn e Zn, respectively

Made available in DSpace on 2014-10-09T12:45:48Z (GMT). No. of bitstreams: 0 / Made available in DSpace on 2014-10-09T14:08:04Z (GMT). No. of bitstreams: 1 07180.pdf: 2177346 bytes, checksum: d1f2f53eb23c2ddfdbc3a34882163240 (MD5) / Tese (Doutoramento) / IPEN/T / Instituto de Pesquisas Energeticas e Nucleares - IPEN/CNEN-SP

Made available in DSpace on 2014-06-11T19:29:35Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-08-29Bitstream added on 2014-06-13T18:59:09Z : No. of bitstreams: 1 nogueira_cz_me_botfm.pdf: 406786 bytes, checksum: 4f06b152f2b5c1591b14b7babbb4bef6 (MD5) / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / O condicionamento aeróbio está associado à redução de níveis pressóricos e outros fatores de risco cardiovascular em hipertensos. A relação entre FC e VO2 durante o exercício progressivo é utilizada para prescrição do exercício físico. O objetivo deste ensaio clínico é investigar os efeitos de um programa de treinamento aeróbio supervisionado de 14 semanas sobre o condicionamento aeróbio e a relação FCVO2, com intuito de avaliar a prescrição inicial baseada na FC. Hipertensos não medicados sedentários, n=55, PAS/PAD(24hs)= 141±11/90±9 mmHg, idade= 49±9 anos, foram submetidos ao treinamento físico aeróbio (esteira elétrica, 50- 70%VO2máx, 3-5 sessões/sem, 45 min/sessão) e avaliados pré e pós treinamento por teste ergoespirométrico. Após 3 meses de exercício, o treinamento aeróbio promoveu um aumento de 7% no VO2máx e 10% no tempo de permanência no teste ergoespirométrico (p<0,0001). O condicionamento aeróbio obtido com o treinamento diminuiu significativamente a FC na mesma intensidade absoluta e não modificou a FC entre 50 e 70%VO2máx e a relação FC-VO2. A resposta do VO2máx ao treinamento aeróbio é variável e depende das características individuais. Assim, o grupo de hipertensos foi dividido em tercis, de acordo com o aumento no VO2máx e comparado o subgrupo do tercil inferior (n=20, ΔVO2máx= 0,2±0,6 ml/kg/min) com o subgrupo do tercil superior (n=19, ΔVO2máx= 4,0±1,1 ml/kg/min). O subgrupo “alto respondedor” apresentou redução significativa na FC para o mesmo VO2. Assim, uma vez determinada a relação FC-VO2 do indivíduo, a mesma faixa de FC pode ser utilizada como estimativa da intensidade de exercício ao longo de um programa de treinamento físico aeróbio. Realizar o teste incremental não é necessário para ajustar a prescrição do exercício em hipertensos após 14 semanas de treinamento aeróbio... / The aerobic conditioning is associated with the reduction of blood pressure levels and with other cardiovascular risk factors in hypertensive subjects. The relationship between heart rate (HR) and oxygen uptake (VO2) during the progressive exercise is used to prescribe the exercise program. The present clinical study is aimed at examining the effects of a 14-week supervised aerobic training program on the aerobic conditioning and the HR/VO2 relationship, to evaluate the initial prescription based on the HR. Sedentary hypertensive people that are not medicated, n = 55, SBP/DBP (24 hours) = 141 ± 11/90 ± 9 mmHg, age = 49 ± 9 years, were subjected to the aerobic physical training (electrical treadmill, 50-70%VO2max, 3-5 sessions/week, 45 minutes/session) and evaluated by means of ergospirometric tests before and after the training. After 3 months of exercises, the aerobic training promoted an increase of 7% in VO2max and of 10% in the permanence time in the ergospirometric test (p < 0.0001). The aerobic conditioning obtained with the training lowered the HR significantly in the same absolute intensity and did not modify the HR between 50 and 70%VO2max and the HR-VO2 relationship. The VO2max response to aerobic training is variable and it depends on individual characteristics. Therefore, the group of hypertensive subjects was divided in tertiles according to the increase in VO2max, and the low tertile (n = 20, ΔVO2max = 0.2 ± 0.6 ml/kg/min) was compared with the high tertile (n = 19, ΔVO2max = 4.0 ± 1.1 ml/kg/min). The “high responder” subgroup presented a significant reduction in the HR for the same VO2. Therefore, since the subject’s HR-VO2 relationship is linear, the same HR can be used as an estimate of the exercise intensity during an aerobic physical training program. It would be not necessary to perform a new incremental test to adjust the exercise prescription for hypertensive subjects after 14 weeks of aerobic training.

Orientador: Roberto Carlos Burini / Banca: Paulo Henrique Waib / Banca: Maria Urbana Pinto Brandão Rondon / Resumo: O condicionamento aeróbio está associado à redução de níveis pressóricos e outros fatores de risco cardiovascular em hipertensos. A relação entre FC e VO2 durante o exercício progressivo é utilizada para prescrição do exercício físico. O objetivo deste ensaio clínico é investigar os efeitos de um programa de treinamento aeróbio supervisionado de 14 semanas sobre o condicionamento aeróbio e a relação FCVO2, com intuito de avaliar a prescrição inicial baseada na FC. Hipertensos não medicados sedentários, n=55, PAS/PAD(24hs)= 141±11/90±9 mmHg, idade= 49±9 anos, foram submetidos ao treinamento físico aeróbio (esteira elétrica, 50- 70%VO2máx, 3-5 sessões/sem, 45 min/sessão) e avaliados pré e pós treinamento por teste ergoespirométrico. Após 3 meses de exercício, o treinamento aeróbio promoveu um aumento de 7% no VO2máx e 10% no tempo de permanência no teste ergoespirométrico (p<0,0001). O condicionamento aeróbio obtido com o treinamento diminuiu significativamente a FC na mesma intensidade absoluta e não modificou a FC entre 50 e 70%VO2máx e a relação FC-VO2. A resposta do VO2máx ao treinamento aeróbio é variável e depende das características individuais. Assim, o grupo de hipertensos foi dividido em tercis, de acordo com o aumento no VO2máx e comparado o subgrupo do tercil inferior (n=20, ΔVO2máx= 0,2±0,6 ml/kg/min) com o subgrupo do tercil superior (n=19, ΔVO2máx= 4,0±1,1 ml/kg/min). O subgrupo "alto respondedor" apresentou redução significativa na FC para o mesmo VO2. Assim, uma vez determinada a relação FC-VO2 do indivíduo, a mesma faixa de FC pode ser utilizada como estimativa da intensidade de exercício ao longo de um programa de treinamento físico aeróbio. Realizar o teste incremental não é necessário para ajustar a prescrição do exercício em hipertensos após 14 semanas de treinamento aeróbio... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: The aerobic conditioning is associated with the reduction of blood pressure levels and with other cardiovascular risk factors in hypertensive subjects. The relationship between heart rate (HR) and oxygen uptake (VO2) during the progressive exercise is used to prescribe the exercise program. The present clinical study is aimed at examining the effects of a 14-week supervised aerobic training program on the aerobic conditioning and the HR/VO2 relationship, to evaluate the initial prescription based on the HR. Sedentary hypertensive people that are not medicated, n = 55, SBP/DBP (24 hours) = 141 ± 11/90 ± 9 mmHg, age = 49 ± 9 years, were subjected to the aerobic physical training (electrical treadmill, 50-70%VO2max, 3-5 sessions/week, 45 minutes/session) and evaluated by means of ergospirometric tests before and after the training. After 3 months of exercises, the aerobic training promoted an increase of 7% in VO2max and of 10% in the permanence time in the ergospirometric test (p < 0.0001). The aerobic conditioning obtained with the training lowered the HR significantly in the same absolute intensity and did not modify the HR between 50 and 70%VO2max and the HR-VO2 relationship. The VO2max response to aerobic training is variable and it depends on individual characteristics. Therefore, the group of hypertensive subjects was divided in tertiles according to the increase in VO2max, and the low tertile (n = 20, ΔVO2max = 0.2 ± 0.6 ml/kg/min) was compared with the high tertile (n = 19, ΔVO2max = 4.0 ± 1.1 ml/kg/min). The "high responder" subgroup presented a significant reduction in the HR for the same VO2. Therefore, since the subject's HR-VO2 relationship is linear, the same HR can be used as an estimate of the exercise intensity during an aerobic physical training program. It would be not necessary to perform a new incremental test to adjust the exercise prescription for hypertensive subjects after 14 weeks of aerobic training. / Mestre