INTRODUÇÃO: A globalização da pesquisa clínica no mundo está fortemente ligada ao processo de internacionalização e terceirização de Pesquisa e Desenvolvimento (P&D) da indústria farmacêutica. A escolha do local de sua execução envolve considerações sobre custo, recrutamento de pacientes, infraestrutura e ambiente ético-regulatório em pesquisa científica. O Brasil tem cenário favorável para condução da pesquisa clínica por apresentar grande massa populacional, com população heterogênea, além de alta incidência de doenças, condições climáticas distintas, médicos capacitados, adequada estrutura de centros de pesquisas e, principalmente, observância dos princípios de boas práticas clínicas. Entretanto são escassos os dados de modelos de gerenciamento aplicados aos centros de pesquisa no país.Influenciada por esse contexto, esta dissertação propõe desenvolver um modelo para o gerenciamento de projetos de pesquisa no cenário público-privado e privado. MÉTODOS: Estudo transversal prospectivo com aplicação de um questionário específico para centros de pesquisa no país. Este instrumento avaliou a aplicação prática das dez áreas de conhecimento (gerenciamento da integração, do escopo, do tempo, de custos, de qualidade, de recursos humanos, de comunicações, de riscos, de aquisições e partes interessadas) do Project Management Body of Knowledge (PMBOK®) com relação à prática diária da pesquisa clínica nos centros de pesquisa do país. RESULTADOS: 55 centros responderam ao questionário completo. Em 37 deles (67,3%) o profissional com o cargo de gerente de projetos é inexistente; não há escritório de gerenciamento de projetos (EGP) em 41 centros (74,5%). O controle de despesas e receitas é realizado por 50 centros (90,9%), porém 28(50,9%) realizam avaliação da rentabilidade. Quanto ao gerenciamento da qualidade, 28 centros (50,9%) não têm parâmetros de qualidade implantados e 11 (40,7%) não realizam auditoria interna. Falhas de comunicação estão presentes em 48 centros (87,2%). A partir da avaliação da aplicação prática das dez áreas de conhecimento do Guia PMBOK® foi desenvolvido o modelo de gerenciamento de projetos com aplicabilidade dos conceitos, ferramentas e técnicas aos centros de pesquisa clínica.CONCLUSÕES: Com a aplicação deste modelo, é possível que os centros tenham uma melhor definição do escopo de cada projeto, que os custos e prazos possuam baixa margem de variabilidade, que se estabeleça uma boa comunicação entre as partes envolvidas e que o impacto econômico do gerenciamento possa ser reconhecido. / INTRODUCTION: The globalization of clinical research in the world is strongly linked to the internationalization and outsourcing process of research and development (R&D) of the pharmaceutical industry and the place of implementation choice involves considerations about cost, patient recruitment, infrastructure and ethical- regulatory framework in scientific research. Brazil has a favorable scenario for conducting clinical research because it has a large population, with a heterogeneous population, high incidence of diseases, different climatic conditions, trained physicians, adequate structure of research centers and mainly compliance with the principles of good clinical practice. However, data on management models applied to research centers in Brazil are scarce. Influenced by this context, this dissertation proposes to develop a model for the management of research projects, in the public-private and private scenarios. METHODS: This was a prospective cross - sectional study with the application of a specific questionnaire for research centers in the country. This instrument evaluated the practical application of the 10 areas of knowledge (management of integration, scope, time, costs, quality, human resources, communications, risks, acquisitions and stakeholders) of Project Management Body of Knowledge (PMBOK®) in relation to the daily practice of clinical research in the country's research centers. RESULTS: 55 centers answered the complete questionnaire. The professional with the position of project manager does not exist in more than half of the active centers in the country 37 (67.3%); there is no project management office (EGP) in 41 (74.5%) centers. The control of expenses and revenues is carried out by 50 (90.9%) centers; however, 28 (50.9%) carry out an evaluation of the profitability. Regarding quality management, 28 (50.9%) did not have quality parameters implanted and 11 (40.7%) did not perform internal audit. Communication failures are present in 48 (87.2%) centers. Based on the evaluation of the practical application of the 10 knowledge areas of the PMBOK® Guide, the project management model was developed with applicability of concepts, tools and techniques to clinical research centers. CONCLUSIONS: With the application of this model, it is possible that the centers have a better definition of the scope of each project, the costs and deadlines have a low margin of variability, a good communication between the parties is established and the economic impact of the management can be recognized.

This project is a Progam Manual for the International Business Academy of La Sierra High School for at-risk students to show how to successfully run an academy and graduate students in compliance with the California High School Exit Exam.

Solicitud de embargo por publicación en revista indexada. / El estudio buscó determinar la relación entre la autoeficacia y la felicidad en estudiantes de academias preuniversitarias de Lima Metropolitana que aspiran a ingresar a la universidad. Participaron 303 estudiantes preuniversitarios, cuyas edades oscilaron entre los 16 a 23 años (M= 18.05; DE= 1.252), quienes resolvieron la Escala de Autoeficacia General y la Escala de Felicidad de Lima. Los resultados evidencian una alta correlación positiva y estadísticamente significativa entre la autoeficacia y las dimensiones sentido positivo de la vida, satisfacción con la vida y alegría de vivir. A su vez, se halló una relación positiva, moderada y estadísticamente significativa entre la autoeficacia y la dimensión realización personal. Por otra parte, no se encontraron diferencias en la autoeficacia y felicidad considerando el sexo, área de la carrera elegida, tipo y ubicación del colegio de procedencia. Sobre la base de los resultados, se resalta la importancia de desarrollar competencias emocionales en los estudiantes preuniversitarios. / The study goal is to determine the relationship between self-efficacy and happiness in students from pre university academies in Lima Metropolitan. A sample of 303 pre-university students, whose ages ranged from 16 to 23 years (M = 18.05; SD = 1,252), they answered General Self-efficacy Scale and Lima Happiness Scale. The results show a high positive and statistically significant correlation between self-efficacy and the dimensions positive meaning of life, satisfaction with life and joy of living. In turn, a positive, moderate and statistically significant relationship was found between self-efficacy and the dimension of personal fulfillment. Also, no differences were found in self-efficacy and happiness considering sex, area of ​​the chosen career, type and location of the high school. Based on the results, the importance of developing emotional competencies in pre-university academies students is highlighted. / Tesis

Minority students are lagging behind their non-minority peers in academic achievement. Compounding this problem is the lack of research on minority students' perceptions on their connections to school, their feelings of autonomy, and their relationship with their parents. These variables are important considerations in this problem, as Ryan and Deci's self-determination theory suggests a strong relationship between student performance in school and students' perceptions of their intrinsic and extrinsic motivators. To address that gap, this cross-sectional, quantitative research study examined the relationship between minority high school students' perceived self-efficacy, locus of control, and parents' educational involvement on their self-reported academic achievement at a suburban charter high school. Differences in these variables by grade level and gender were also assessed. A convenience sample of 158 male and female students in the 10th, 11th, and 12th grades completed the Self-in-School instrument, Levenson Multidimensional Locus of Control Inventory, Importance of Parent Involvement Scale, and a demographic survey that included self-reported academic achievement. Regression analyses and multivariate analysis of variance revealed that school self-efficacy and students' perception of parental involvement of minority students were statistically significant predictors of self-reported academic achievement. No statistically significant differences were found on the 3 scales by grade, but statistically significant differences were obtained between male and female minority students' perception of parental involvement on their academic achievement. These findings may contribute to social change by helping mental health professionals and educators understand the importance of psychosocial variables in charter students' academic performance.

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ABSTRACT EFFECT OF INITIAL SUPPORT OF EXCAVATION ON SEISMIC PERFORMANCE OF CUT AND COVER STRUCTURES Rezaei, Hamidreza M.Sc., Department of Civil Engineering Supervisor: Asst. Prof. Dr. Alp Caner MAY 2011, 66 pages The effect of the initial support and its embedment depth, on the seismic performance of cut and cover tunnels is investigated. Cut and cover construction is one of the fastest and cheapest methods for constructing rectangular shallow tunnels. Construction of cut and cover structure in soil usually starts with installation of the initial support of excavation system, which may consists of rigid type of initial supports such as tangent piles or secant piles. These systems usually remain in place after completion of the final structure. However, to simplify the design, it is a common practice to ignore the contribution of initial support. In this study the effect of initial support of excavation on the seismic performance of cut and cover tunnels is investigated by means of a detailed dynamic finite element analysis. Three different tunnel geometries, three soil types and three acceleration histories were considered Results of the study show that depending on the soil stiffness (soft, medium, or stiff soil), the dynamic response of the tunnel deformations are affected significantly by the initial support of excavation. The effect of the initial support diminishes as the quality of the soil improves. Therefore, dynamic analyses are recommended for the final design of this type of structures especially in soft soils.

This study explores the ways in which objects are used in the organization of daily life, by specifically focusing on the use of prayer beads and their mechanical and digital variations. For this purpose, a framework based on material culture and practice theory is employed to understand how Islam informs and guides the organization and the conduct of daily life around the pervasive prayer practices, the ways objects are used for these purposes and how practices and products co-evolve by influencing each other. Fieldwork with devout Muslims, who are using prayer beads together with mechanical and digital counters for their daily praying practices, is conducted by employing ethnomethodology. Findings on the ways in which objects are used, utilized, appropriated and adopted within the socio-cultural and political dynamics of Islam in Turkey are analysed regarding the social and practical aspects of daily life such as the organization of daily life and daily practices, the core issues shaping these practices, thus objects, how identity discourse reflected on/by the use of objects and the ensemble of products that is orchestrated for a meaningful organization of daily life around prayer practices.

Philip Doddridge (1702-51) was pastor of the Independent congregation meeting at Castle Hill, Northampton, and tutor of the Northampton academy from 1729 to his death in 1751. He is regarded as a leader of moderate Dissent during that period and the heir, theologically and pastorally, of Richard Baxter. He has been seen as forming a bridge between the more rational Dissenters, on the one hand, and the more conservative and orthodox wing of Dissent on the other. His thought has not, however, been the subject of a detailed analysis in the context of his time. This thesis sets out to conduct such an analysis in order to examine more closely his position within early eighteenth-century Dissent. Doddridge’s philosophical and theological views are considered in chapters two to five. Chapter two assesses the extent of his indebtedness to the philosophy of John Locke, examining also the views of Isaac Watts and showing how Doddridge and Watts modified Locke’s thought in some areas in order to accommodate Christian beliefs. In chapter three, Doddridge’s views on natural theology, natural law and reason are considered and the influence on him of Samuel Clarke, in particular, is examined. Turning to theology, chapter four looks at the use in early eighteenth-century Dissent of terms such as ‘Baxterian’ and ‘moderate Calvinist’ and then considers Doddridge’s doctrinal positions on a range of subjects which are generally considered to represent Baxterian theology. Chapter five examines Doddridge’s views on the key interconnected areas of confessional subscription, scripture and the doctrine of the Trinity. Practical subjects are then considered in chapters six to eight. Doddridge’s views on Christian piety are examined in chapter six. Chapter seven considers ways in which Doddridge sought to communicate, examining the audiences whom he aimed to reach, the ways in which he attempted to reach them and the content of what he wanted to say. The eighth chapter looks at the subject of identity and argues that Doddridge is to be viewed, not so much as a bridge between different wings of Dissent, but as a leader amongst moderate Calvinists. In conclusion, this thesis argues that Philip Doddridge sought to expound a Calvinist theology in the context of the philosophical and theological debates of his day and to promote an ordered Dissent focused on central evangelical truths and united around the language of scripture.

Orientador: Mara Regina Martins Jacomeli / Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Educação / Made available in DSpace on 2018-08-14T20:17:48Z (GMT). No. of bitstreams: 1 Almeida_EnioAntoniode_M.pdf: 2909042 bytes, checksum: 22a9b5136762906c97b2651f97e788c9 (MD5) Previous issue date: 2009 / Resumo: A presente dissertação elucida a história da instituição de ensino militar paulista, Academia do Barro Branco, localizada na zona norte da capital, notadamente quanto ao momento da criação dessa escola de formação de oficiais da então Força Pública, fato ocorrido em 1913 com a publicação da Lei Estadual que criava o Curso Especial Militar, com a colaboração de uma missão estrangeira de instrução militar. Esse grupo foi contratado pelo governo estadual paulista junto ao exército francês, e seus trabalhos se iniciaram em 1906. Como verificamos na pesquisa, a criação da Academia visou à manutenção da hegemonia política da oligarquia cafeeira do oeste paulista em todo país. A atual Academia do Barro Branco é o local onde são formados os profissionais da área de segurança pública, responsáveis pelo comando dos policiais militares que atuam em todas as cidades do Estado de São Paulo no atendimento emergencial da população em casos de crimes e outras demandas públicas, bem como no policiamento ostensivo para preservar aquilo que o capitalismo define como ordem pública. Essa escola militar, portanto, resulta de um processo histórico iniciado a partir da profissionalização da então Força Pública durante a República Velha, empreendimento eivado do ideário republicano e demais ideologias que permeavam o discurso educacional da época. Metodologicamente, para a elaboração do trabalho, foi procedido amplo levantamento bibliográfico sobre o período e a temática; recorrendo-se também às fontes primárias relativas à criação e implementação da Academia. Em seus capítulos, verificam-se a contextualização histórica na transição Império-República, o histórico da força policial paulista até o período de interesse da pesquisa e a inserção do objeto de estudo na legislação da época; descreve-se a invernada do Barro Branco - local escolhido para a instalação da escola pesquisada - e analisa-se a evolução curricular do Curso de Formação de Oficiais. / Abstract: This dissertation elucidates the history of the Military Training School named "Barro Branco" Academy, located in the north of the capital city, São Paulo, mainly regarding the particular occasion of the creation of this training school for officers of the then Public Force, what took place in 1913 when the State Law was promulgated and the Special Military Course was created with the cooperation of a foreign mission for military training. The Sao Paulo State Government made an agreement with the French Army and the work of the foreign group started in 1906. As it can be observed in the research, the purpose of creating the Academy was to keep on the political hegemony of the coffee oligarchy from the west of São Paulo throughout the country. The "Barro Branco" Academy is now the place where professionals of the public safety area are trained to be responsible for the command of military officers who work in all the towns and cities of São Paulo State providing the population with emergency care concerning crimes and other public demands as well as ostensible policing in order to preserve what the capitalism calls public order. This military school, therefore, is the result of a historical process, which began with the professionalization of the then Public Force during the Old Republic, and reflects the Republican Thinking together with other ideologies that permeated the educational speech of the time. Methodologically, to elaborate this dissertation, an extensive bibliography survey was performed on the period of the facts and on the main theme, making use of the primary sources related to the creation and implementation of the Academy. In its chapters, it is possible to observe the historical context during the transition period from the Empire to the Republic System as well as a detailed report on the police force in São Paulo up to the research period of interest and the insertion of the object of study in the legislation of the time. It is also described the development of the "Barro Branco Academy", the place where the researched training school was installed. In the end, an analysis is made on the curricular evolution of the Officers Training Course. / Mestrado / Filosofia e História da Educação / Mestre em Educação

This study contributes to the current literature on time, gender, migration, culture and identity by bringing insights into how time is perceived and experienced by Syrian women who are settled and working in the UK. It is a topic that is little known in the extant literature, and that differs in its dynamics form the western literature. The notion of time has been widely debated but with little reference to its impact on the perceptions and individual experiences of migrant women, who engage with culturally different time structures and different time schedules. The spatial experiences of those women represented by their mobility across cultural boundaries seem to be affecting how migrant women perceive and organise time. Throughout the study, the Heideggerian interpretive phenomenological perspective has been adopted to make sense of and interpret the meanings and experiences provided by the participants of this study. This has been selected to allow space for considering and acknowledging the impact of the personal experience and prior knowledge of both the researcher and the researched subjects. Perceptions of time and time experiences have been found to be much diversified across personal, social and cultural contexts which are marked by spatial or geographical boundaries. Also, time structures and time schedules have been institutionally gendered across the cultures of both countries: Syria and the UK, but with varying degrees. Empirically, this study can help work organisations and agencies interested in working with migrant people to understand the diversity of perceptions and experiences of migrant female workers in the UK to enable them offering the care and services tailored to the needs of those migrants. In doing so, this research is hoped to improve the quality of work and social contributions of migrant women in the UK. Methodologically, this phenomenological inquiry contributes to the field of empirical and socio-political knowledge as well as the understanding of moral, aesthetic, and personal welfare debated in the migration literature. It contributes to the understanding of human experiences in relation to the notion of time, in isolation of any concern to predicting or prescribing any theory.