The pandemic of HIV/AIDS has been felt by nations throughout the world. It is a well-known fact that the AIDS epidemic is catastrophic in sub Saharan Africa, which heads the list of the most affected regions. As the epidemic imposes a strain on the already limited resources, a better understanding of the disease is continuously being sought out. This understanding is enhanced with better information dissemination. The present research aims to assist the information requirements of HIV/AIDS researchers in the country through a bibliometric study. The present study comprised an investigation of the patterns of authorship and publications of academic institutions in the sciences, medical institutions and affiliated organizations in South Africa, focusing on HIV/AIDS literature for the two decade period, 1982-2002. Published literature in the sciences and medicine from three internationally recognised databases were used for the assessment. They were: AIDSearch, lSI Science Citation Index Expanded and MEDLINE (OVID). A total of 2 281 documents formed the basis for the assessment. The results of the study are presented, as are their consequences for researchers and policy makers. Some recommendations are provided for the developers and designers of databases. The results of the study demonstrate exponential growth in the literature as might be expected. Because of the multidisciplinary nature of the disease, research is scattered in a variety of discipline-based journals. Researchers publish mainly in journals and the South African Medical Journal is the most productive in the field of HIV/AIDS. Collaboration in research on the subject is evident. The results also demonstrate that South African researchers are fast becoming internationally recognized in the field of HIV/AIDS research. The Medical Research Council emerged as the leader in South Africa's research efforts on HIV/AIDS. Of the academic institutions, the University of the Witwatersrand is the most productive institution, followed by the University of Natal. / Thesis (M.I.S.)-University of KwaZulu-Natal, Pietermaritzburg, 2003.

Parks and protected areas are crucial for the health of the biosphere and long-term sustainability of the planet. However challenges these areas face include: there are simply not enough of them, the existing ones are often too small and fragmented, and there is not always public support for them. Regional parks are specific types of protected areas that can help contribute to conservation and sustainability. The effectiveness of protected areas for conservation can be enhanced through a variety of strategies such as “biosphere reserves”. This research looks at stakeholder perceptions regarding potential benefits of the Mount Arrowsmith Massif Regional Park and the importance of the Mount Arrowsmith Biosphere Reserve Operating Framework. This study has contributed to the larger Protected Areas and Poverty Reduction (PAPR) research initiative as it discusses the flow of costs and benefits from protected areas and alternate forms of protected area governance.

The anti-inflammatory properties of four medicinal plants were investigated. These plant extracts were subjected to screening for their possible effects as antioxidative, analgesic, and anti-inflammatory agents. In the antioxidant activity, the Plantago lancelota extracts resulted in an IC50 value of 0.4 mg/mL compared to the positive control quecertin with IC50 0.04 mg/mL Plantago lanceolata inhibited COX-2 activity with IC50 values of 0.41 mg/mL. However, the COX-1 inhibition indicated an IC50 of 68.99 mg/mL. The lipoxygenase assay indicated that Plantago lanceolata was the most active plant species with an IC50 value of 4.86 mg/mL compared to the positive control (quecertin) with an IC50<2mg/mL. The nitric oxide assay of the plant extracts indicates a dose-dependent activity of our plant extracts. Likewise the cell viability result indicated a good activity at dose 100 mg/mL. / Life and Consumer Sciences / M. Sc. (Life Sciences)

Government policies on subsidising higher education institutions may have a direct impact on the behaviour of researchers and managers respectively. Therefore, this thesis looks for clues on how higher education institutions respond to the government funding policies, with special reference to the New Funding Framework (NFF) introduced in South Africa in 2001. The funding framework specified that research funding would be determined only on the basis of research output. The NFF puts emphasis on the number of publications produced by higher education institutions per annum to determine their subsidy amounts. Governments use quantitative formulas to allocate research funds to higher education institutions based on their production of output. The current South African funding framework is arguably consistent with some international suggestions of the role that government funding can play in the implementation of national higher policies. This thesis uses higher education research output as a measure of knowledge production. As such, the thesis was set out to determine the effects that the research subsidy component of the NFF might have had on South African public higher education institutions‟ knowledge production between 2001 and 2006. The thesis argues that the subsidy component of the NFF has had positive effects on the knowledge production of South African public higher education institutions (HEIs). An empirical analysis of the output trends of South African HEIs for the period under review has shown a steady increase, more especially from 2003. The thesis attributes the new trend in higher education research output to the successful implementation of the NFF. It is thus concluded that considering the output trends of the period under review, the implementation of the NFF is yielding positive effects towards achieving its intended goal of increasing research output of South African public HEIs. / Public Administration / D. Admin. (Public Administration)

Government policies on subsidising higher education institutions may have a direct impact on the behaviour of researchers and managers respectively. Therefore, this thesis looks for clues on how higher education institutions respond to the government funding policies, with special reference to the New Funding Framework (NFF) introduced in South Africa in 2001. The funding framework specified that research funding would be determined only on the basis of research output. The NFF puts emphasis on the number of publications produced by higher education institutions per annum to determine their subsidy amounts. Governments use quantitative formulas to allocate research funds to higher education institutions based on their production of output. The current South African funding framework is arguably consistent with some international suggestions of the role that government funding can play in the implementation of national higher policies. This thesis uses higher education research output as a measure of knowledge production. As such, the thesis was set out to determine the effects that the research subsidy component of the NFF might have had on South African public higher education institutions‟ knowledge production between 2001 and 2006. The thesis argues that the subsidy component of the NFF has had positive effects on the knowledge production of South African public higher education institutions (HEIs). An empirical analysis of the output trends of South African HEIs for the period under review has shown a steady increase, more especially from 2003. The thesis attributes the new trend in higher education research output to the successful implementation of the NFF. It is thus concluded that considering the output trends of the period under review, the implementation of the NFF is yielding positive effects towards achieving its intended goal of increasing research output of South African public HEIs. / Public Administration and Management / D. Admin. (Public Administration)