Despite substantial healthcare costs, patient outcomes are sub-optimal in the United States and Canada compared to other countries that spend proportionally less on healthcare. This has led to recognition of the need to improve healthcare value, utilization of tools including clinical practice guidelines and development of initiatives such as the Choosing Wisely Campaign to achieve this goal. In spite of the intuitive appeal of these interventions designed to increase physician awareness of evidence and empower patients to engage in shared decision-making, they have had limited success in changing practice and physician prescribing behaviours. Using a mixed-methods approach, this thesis represents a purposeful attempt to understand the failure of existing approaches through an examination of the factors that influence clinical decision making. Specifically, the thesis integrates quantitative and qualitative methodologies to develop a deeper understanding of clinical decision-making. Consisting of a clinical vignette based survey, the quantitative study explores decision-making in four specific commonly encountered case contexts. After choosing the preferred management option, participants rated the influence of different factors on their decisions. Follow-up questions explored knowledge, attitudes and practices regarding incorporating cost considerations into decision-making. The results of the study were explored further in the qualitative component of the mixed study. The results indicate that clinical decision-making is influenced by an interrelated set of socioecological factors with evidence and clinical practice guidelines playing a secondary role. Because lack of knowledge is not a major factor in guideline discordant care, strategies to improve knowledge will have minimal effect in improving care. The qualitative study included an inquiry into the need for teaching and learning on the topic of cost and cost-effectiveness and sought input from physicians working in diverse settings on methods and topics that need to be included in medical education. The contributions of this thesis include a deeper understanding of the factors that influence clinical decision-making and suggestions for enhancing medical education. / Thesis / Doctor of Philosophy (PhD) / Despite the highest health-care expenditure in the world, patient health outcomes are suboptimal in the United States (US). Additionally, out-of-pocket patient costs are increasingly a cause of financial distress to American patients. Although Canada spends comparatively less than the US on healthcare, it is one of the top ten countries for healthcare spending as a proportion of the gross domestic product. In spite of this level of spending, patient outcomes in the US and Canada are worse when compared to many other economically developed countries that spend relatively less on healthcare. A substantial portion of healthcare spending is for services that do not improve patient outcomes while services proven to improve patient outcomes are underused. Utilizing sequential quantitative and qualitative studies this thesis is a purposeful attempt to identify and examine the factors that influence clinical decision making by physicians. The knowledge gained in this study may help inform the development and evaluation of strategies targeted at increasing adoption of evidence-based practices leading to improved health-outcomes at affordable costs.

Background: Diagnosis of acute coronary syndromes (ACS) in the Emergency Department (ED) is a topical and contentious issue. Current diagnostic techniques rely on hospital admission for troponin testing. Only a minority of those admitted prove to have ACS while unacceptable proportions of those discharged have unrecognised ACS. Aims: We aimed to evaluate the diagnostic and prognostic value of individual clinical findings and novel biomarkers in ED patients with suspected cardiac chest pain. We then aimed to derive a clinical decision rule (CDR) to potentially enable safe, immediate discharge of a proportion of patients from the ED while risk stratifying others to facilitate triage to an appropriate level of in-patient care. Methods: We recruited patients who presented to the ED with suspected cardiac chest pain. Variables that have previously been shown to predict diagnosis of acute myocardial infarction (AMI) or to predict outcome were prospectively recorded. Blood was drawn at presentation for levels of eight biomarkers. Patients underwent 12-hour troponin testing and were followed up for the composite primary outcome of AMI, death or urgent coronary revascularisation for six months. Variables that were univariate predictors (p<0.05) of outcome were entered into a multivariate analysis using recursive partitioning. Results: While many clinical findings and levels of all eight novel biomarkers were found to be significant predictors of outcome, none could be used individually to confirm or exclude ACS in the ED. We derived a nine-point CDR that combined clinical findings with biomarker levels to effectively stratify patients into four risk groups. 14.2% of patients were identified as being at ‘no risk’ and had a 0.0% outcome rate. The rule performed significantly better than two commonly used risk scores and may improve on triage decisions made in actual clinical practice. Conclusion: ACS remains a difficult diagnosis to confidently confirm or refute in the ED. Our CDR may help to avoid unnecessary hospital admissions while improving on triage decisions made for the remaining in-patients. Prospective validation of our findings is warranted.

Introdução: A doença pulmonar na fibrose cística (FC) é obstrutiva e supurativa, caracterizada por exacerbações recorrentes dos sintomas respiratórios e pela deterioração progressiva da função pulmonar. A gravidade da doença pulmonar é mensurada pelo volume expiratório forçado no primeiro segundo (VEF1), obtido através da espirometria. O VEF1 é um preditor de mortalidade bem documentado na literatura, utilizado como desfecho em ensaios clínicos e como parâmetro para indicar e monitorizar respostas terapêuticas. O objetivo do estudo foi avaliar o impacto da realização da espirometria em todas as consultas médicas na frequência das intervenções clínicas e na função pulmonar dos pacientes com FC. Métodos: Pacientes com diagnóstico de FC em acompanhamento em centro de referência, com idade entre 5-18 anos, realizaram uma espirometria antes de cada consulta médica durante o período de um ano (2014). Os dados coletados durante o seguimento foram comparados com o período de 24 meses anteriores ao estudo, período no qual os pacientes realizavam rotineiramente apenas uma espirometria a cada seis meses. Os principais desfechos avaliados foram diagnóstico de exacerbação pulmonar, frequência de introdução de novas terapias de uso crônico, encaminhamento ao ambulatório de transplante pulmonar e média do VEF1 basal. A utilização da espirometria para tomada de decisão clínica foi referida pelo médico assistente através de questionário. Resultados: Participaram do estudo 80 pacientes (idade média 12,1 anos e 61,3% do sexo masculino), tendo sido realizadas 418 consultas durante o ano de seguimento (5,2 consultas por paciente/ano). Exacerbações pulmonares foram diagnosticadas em 27,5% das consultas, com taxa de 1,44 exacerbações pulmonares por paciente/ano, frequência significativamente maior quando comparada com os anos 2012 (p=0,001) e 2013 (p=0,05). A espirometria foi útil para diagnóstico de exacerbação pulmonar em 83,5% das vezes, e em 21,9% destes casos o diagnóstico de exacerbação foi feito exclusivamente pelo parâmetro do declínio agudo do VEF1. Terapias de uso crônico foram introduzidas 0,4 vezes por paciente/ano, sem diferença estatisticamente significante com os períodos anteriores. A espirometria foi útil em 83,9% das vezes em que se iniciou uma nova terapia. Foram realizados três encaminhamentos para o serviço de transplante pulmonar, sem diferença estatística com os períodos anteriores. A média do VEF1 basal da amostra foi de 80% do previsto (DP+28,2), sem diferença significativa com os valores observados nos anos anteriores 78,1% em 2013 (p=0,27); e 76,7% em 2012 (p=0,7), indicando tendência para manutenção da função pulmonar destes pacientes. Conclusão: O estudo evidencia um impacto significativo da realização da espirometria rotineira em todas as consultas médicas no aumento do reconhecimento e tratamento de exacerbações pulmonares, com potenciais benefícios na função pulmonar destes pacientes / Background: Pulmonary disease in cystic fibrosis (CF) is obstructive and suppurative, characterized by recurrent exacerbations of respiratory symptoms and progressive deterioration of lung function. The severity of lung disease is measured by forced expiratory volume in the first second (FEV1), obtained through spirometry. FEV1 is a well documented predictor of mortality in the literature, used as an endpoint in clinical trials and as a parameter for indicating and monitoring therapeutic responses. The aim of the study was to evaluate the impact of performing spirometry during routine medical visits on the frequency of clinical interventions and lung function in CF patients. Methods: Patients with a diagnosis of CF in follow-up at the reference center, aged 5-18 years, underwent spirometry before each clinical visit during a one-year period (2014). Data collected during follow-up were compared with the 24-month period prior to the study, during which patients routinely performed only one spirometry every six months. The outcomes included diagnosis of pulmonary exacerbation, frequency of introduction of new therapies for chronic use, referral for pulmonary transplantation, mean baseline FEV1. The use of spirometry for clinical decision making was reported by the attending physician by questionnaire. Results: 80 patients (mean age 12.1 years and 61.3% males) participated in the study, and 418 visits were performed during the year of follow-up (5.2 visits per patient/year). Pulmonary exacerbations were diagnosed in 27.5% of the consultations, with a rate of 1.44 pulmonary exacerbations per patient/year, significantly higher than the year of 2012 (p = 0.001) and 2013 (p = 0.05). Spirometry was useful for diagnosis of pulmonary exacerbation in 83.5% of the time, and in 21.9% of these cases the diagnosis of exacerbation was made exclusively by the parameter of the acute decline of FEV1. Chronic use therapies were introduced 0.4 times per patient/year, with no statistically significant difference with previous periods. Spirometry was useful in 83.9% of the times a new therapy was started. Three referrals were made for pulmonary transplantation, with no statistical difference with previous periods. The mean baseline FEV1 of the sample was 80% predicted (SD+28.2), compared to 78.1% in 2013 (p=0.27); and 76.7% in 2012 (p=0.7), indicating a tendency for stabilization of the pulmonary function of these patients. Conclusion: The study evidences a significant impact of routine spirometry during routine encounters of CF patients in the increase of diagnosis and treatment of pulmonary exacerbations, with potential benefits for the pulmonary function of these patients

Doctor of Philosophy / The aim of the research presented in this thesis was to come to a deeper understanding of clinical decision making from within the interpretive paradigm. The project draws on ideas from a number of schools of thought which have the common emphasis that the interpretive use of language is at the core of all human activity. This research project studied settings where health professionals and medical students engage in clinical decision making in groups. Settings included medical students participating in problem-based learning tutorials and a team of health professionals working in a multidisciplinary clinic. An underlying assumption of this project was that in such group settings, where health professionals are required to articulate their clinical reasoning for each other, the individuals involved are likely to have insights that could reveal the nature of clinical decision making. Another important assumption of this research is that human activities, such as clinical reasoning, take place in cultural contexts, are mediated by language and other symbol systems, and can be best understood when investigated in their historical development. Data were gathered by interviews of medical students and health professionals working in the two settings, and by non-participant observation. Data analysis and interpretation revealed that clinical decision making is primarily a social and linguistic skill, acquired by participating in communities of practice called health professions. These communities of practice have their own subculture including the language game called clinical decision making which includes an interpretive repertoire of specific language tools and skills. New participants to the profession must come to embody these skills under the guidance of more capable members of the profession, and do so by working through many cases. The interpretive repertoire that health professionals need to master includes skills with words, categories, metaphors, heuristics, narratives, rituals, rhetoric, and hermeneutics. All these skills need to be coordinated, both in constructing a diagnosis and management plan and in communicating clinical decisions to other people, in a manner that can be judged as intelligible, legitimate, persuasive, and carrying the moral authority for subsequent action.

<p>Physicians are supposed to act as sick-listing experts and they possess a role as gate-keepers to the social insurance system. Earlier studies have demonstrated variation between physicians and physician categories regarding sick-listing practice. In addition to the patient's disease and its severity, a number of other factors may be expected to influence sick-listing practice. Most earlier studies have focused on the patient's disease and his or her work place as cause for sickness absence.</p><p>The aims of this study were to analyse variation of sick-listing practice between physician categories and the influence of physician characteristics on sick-listing practice, the influence of structure, organisation and remuneration of health care on physician sick-listing practice, the influence of local structural factors in the community, and the influence of a legislative change on physician sick-listing practice.</p><p>The study was conducted as a cross-sectional epidemiological study of 57563 doctors’ certificates for sickness absence, received by 28 local social insurance offices in eight Swedish counties, during four months in 1995 and two months in 1996.</p><p>Patient age, sex, and diagnostic group, issuing physician category, presence of a hospital in the municipality, municipality population size and county were all significantly and independently correlated to number of net days of sick-listing. Physician characteristics, such as age, sex and degree of specialisation were all associated with number of net days of sick-listing. Physicians working in general practice issued significantly shorter periods of sick-listing than the other physician categories. Reimbursement of general practice and participation in financial co-operation with social insurance were significantly correlated to length of sickness episode issued by general practitioners. A legislative change performed during the study period was associated with small effects in sick-listing practice.</p><p>In conclusion, a number of factors other than disease and disease severity and other patient and physician linked factors were found to influence the variation of sick-listing practice. It appears that the closer the influencing factor was to the place were the decision was taken, i.e., the patient-physician consultation, the higher the impact on the decision appeared to be.</p>

Physicians are supposed to act as sick-listing experts and they possess a role as gate-keepers to the social insurance system. Earlier studies have demonstrated variation between physicians and physician categories regarding sick-listing practice. In addition to the patient's disease and its severity, a number of other factors may be expected to influence sick-listing practice. Most earlier studies have focused on the patient's disease and his or her work place as cause for sickness absence. The aims of this study were to analyse variation of sick-listing practice between physician categories and the influence of physician characteristics on sick-listing practice, the influence of structure, organisation and remuneration of health care on physician sick-listing practice, the influence of local structural factors in the community, and the influence of a legislative change on physician sick-listing practice. The study was conducted as a cross-sectional epidemiological study of 57563 doctors’ certificates for sickness absence, received by 28 local social insurance offices in eight Swedish counties, during four months in 1995 and two months in 1996. Patient age, sex, and diagnostic group, issuing physician category, presence of a hospital in the municipality, municipality population size and county were all significantly and independently correlated to number of net days of sick-listing. Physician characteristics, such as age, sex and degree of specialisation were all associated with number of net days of sick-listing. Physicians working in general practice issued significantly shorter periods of sick-listing than the other physician categories. Reimbursement of general practice and participation in financial co-operation with social insurance were significantly correlated to length of sickness episode issued by general practitioners. A legislative change performed during the study period was associated with small effects in sick-listing practice. In conclusion, a number of factors other than disease and disease severity and other patient and physician linked factors were found to influence the variation of sick-listing practice. It appears that the closer the influencing factor was to the place were the decision was taken, i.e., the patient-physician consultation, the higher the impact on the decision appeared to be.

Doctor of Philosophy / The aim of the research presented in this thesis was to come to a deeper understanding of clinical decision making from within the interpretive paradigm. The project draws on ideas from a number of schools of thought which have the common emphasis that the interpretive use of language is at the core of all human activity. This research project studied settings where health professionals and medical students engage in clinical decision making in groups. Settings included medical students participating in problem-based learning tutorials and a team of health professionals working in a multidisciplinary clinic. An underlying assumption of this project was that in such group settings, where health professionals are required to articulate their clinical reasoning for each other, the individuals involved are likely to have insights that could reveal the nature of clinical decision making. Another important assumption of this research is that human activities, such as clinical reasoning, take place in cultural contexts, are mediated by language and other symbol systems, and can be best understood when investigated in their historical development. Data were gathered by interviews of medical students and health professionals working in the two settings, and by non-participant observation. Data analysis and interpretation revealed that clinical decision making is primarily a social and linguistic skill, acquired by participating in communities of practice called health professions. These communities of practice have their own subculture including the language game called clinical decision making which includes an interpretive repertoire of specific language tools and skills. New participants to the profession must come to embody these skills under the guidance of more capable members of the profession, and do so by working through many cases. The interpretive repertoire that health professionals need to master includes skills with words, categories, metaphors, heuristics, narratives, rituals, rhetoric, and hermeneutics. All these skills need to be coordinated, both in constructing a diagnosis and management plan and in communicating clinical decisions to other people, in a manner that can be judged as intelligible, legitimate, persuasive, and carrying the moral authority for subsequent action.

A lack of information is identified on the ability of professional nurses working in a neonatal intensive care unit to make competent clinical decisions pertaining to the employment of bedside blood product filters during neonatal transfusion. In addition, a lack of complete guidelines existed to aid professional nurses in instances where they are faced with such a decision. A descriptive survey was conducted to determine and describe the knowledge professional nurses working in neonatal intensive care unit have regarding the employment of bedside blood product filters during the transfusion of a neonate with blood or blood products, as well as their ability to make competent clinical decisions in the regard. A questionnaire was designed, which was validated by experts in neonatal intensive care nursing and blood transfusion. The questionnaires were distributed to 10 nominated public and private hospitals with neonatal intensive care units in Gauteng, South Africa, for completion. Participants were self-nominated; they participated in the study of their own free will. Neither the participants’ nor the hospitals’ names were revealed at any stage. Numbers were used to identify the questionnaires. 120 questionnaires were completed and were analysed using descriptive statistics. In the following step, the results obtained from the questionnaires together with literature were used to recommend guidelines for neonatal transfusion utilisation by professional nurses working in neonatal intensive care units. The recommended guidelines were divided into two categories: General guidelines and Specific blood products guidelines. Validity and reliability was enhanced by using staff from ten neonatal intensive care units from the private and public health care sector in Gauteng, South Africa; obtaining a sufficient sample size (n=120); involvement of experts in the field of neonatal nursing science and blood transfusion, as well as a statistician from the University of Pretoria; and verification of results with literature. Ethical principles were adhered to: confidentiality was maintained as no names of any of the hospitals or the participants were disclosed. All information regarding the study was provided to the relevant parties and the participants voluntarily signed an informed consent form. Permission to conduct the study was obtained from the selected hospitals’ management. Approval to conduct the study was obtained from the Ethics Committee of the Faculty of Health Science, University of Pretoria. There were no known risks involved in the study. Recommendations were made for more research on the same topic to be conducted and their outcomes be compared to the results yielded by this study and research to be conducted to related topics. The findings of this study were meant to improve the clinical practice of nursing in neonatal intensive care units. It was therefore recommended that these guidelines be implemented by neonatal intensive care units, training institutions and the South African Blood Transfusion Services. AFRIKAANS : Die navorser het ’n intensiewe oorsig van die bestaande literatuur rakende die kliniese besluitneming van professionele verpleegkundiges in neonatale intensiewe sorgeenhede gedoen. Dit het duidelik uit dié navorsingsoorsig geblyk dat daar baie min gedoen is om die vermoëns vas te stel van professionele verpleegkundiges wat in die neonatale intensiewe sorgeenheid werk met betrekking tot kliniese besluitneming wat die aanwending van bloedprodukfilters tydens neonatale transfusie betref. Aanvullend het die oorsig onthul dat daar geen volledige riglyne bestaan, of voorsien word, vir professionele verpleegkundiges in gevalle waar hul met so ’n besluit gekonfronteer word. Die studie is in twee fases gedoen. In Fase een is ’n vraelys ontwerp gebaseer op konsepte en temas uit die literatuur geїdentifiseer, waarna dit gevalideer is deur kundiges. Die vraelyste is uitgegee aan 10 genomineerde privaat- en publieke hospitale met neonatale inesiewe sorgeenhede in Gauteng vir voltooiing. Die voltooide vraelyste is gesorteer en geanaliseer. Deelnemers is self-genomineerd; die navorser het hulle toegelaat om self te besluit of hulle wou deelneem aan die studie of nie. Deelnemers en hospitale se name is op geen stadium bekend gemaak nie. Nommers is gebruik om die vraelyste te identifiseer. In Fase twee is die uitslae van die vraelyste gebruik om riglyne te ontwerp om gebruik te word in neonatale intensiewe sorgeenhede deur professionele verpleegkundiges vir neonatale transfusie. Riglyne vir neonatale transfusie is geformuleer volgens die uitkoms van die vraelyste in kombinasie sowel as die oorsig van die reeds bestaande literatuur deur middel van induktiewe en deduktiewe beredenering. Aangesien professionele verpleegkundiges kennis moet dra van algemene riglyne om spesifieke riglyne te kan toepas, is die riglyne in twee kategorieë verdeel: Algemene riglyne en Spesifieke bloedprodukte riglyne. Deur hierdie studie in twee verskillende omgewings, naamlik privaat- en publieke instansies te doen, en 10 eenhede van een area (Gauteng) in Suid- Afrika daarby te betrek, sowel as om ’n relatief groot steekproef te gebruik, is die oordraagbaarheid van die uitkoms van die studie na ander streke verhoog. Die navorser het aanbeveel dat verdere studies oor dieselfde onderwerp gedoen word, en die uitkomste daarvan vergelyk word met die resultaat van hierdie studie. Die uitkoms die studie sal dan meer oordraagbaar wees na ander streke in Suid-Afrika. Die uitgebreide literatuuroorsig, die betrokkenheid van kundiges en die navorser se eie ondervinding en kennis in die neonatale intensiewe sorgverpleegkunde, het bygedra tot die vertrouenswaardigheid van die studie. Kundiges op die gebied van neonatale verpleegkunde en bloedtransfusie was betrokke, sowel as ’n biostatistikus verbonde aan die Universiteit van Pretoria. Etiese beginsels is gevolg. Die navorser was nie bewus van, en is ook nie gekonfronteer met enige etiese dilemmas of probleme tydens die studie nie. Konfidensialiteit is deurgaans gehandhaaf in die studie deurdat geen name van die deelnemers of hospitale genoem is nie. Alle inligting met betrekking tot die studie is aan die relevante partye verstrek en die deelnemers het almal uit eie vrye wil ’n ingeligte toestemmingsvorm onderteken. Toestemming om die studie te doen is ook verkry van die genomineerde hospitale se bestuur. Toestemming om die studie te doen is verkry van die Etiese Komittee van die Fakulteit van Gesondheidswetenskappe, Universiteit van Pretoria. Daar was geen risiko’s betrokke aan die studie nie, slegs voordele, aangesien die doel van die studie was om die professionele verpleegkundiges in die neonatale intensiewe sorgeenhede behulpsaam te wees met besluitneming rakende die gebruik van bloedprodukfilters tydens transfusie van bloed of bloedprodukte aan ’n neonaat. Die bevindings van die studie is bedoel om die kliniese praktyk van verpleging in neonatale intensiewe sorgeenhede te verbeter. Gevolglik word ’n aanbeveling gemaak dat hierdie riglyne geïmplimenteer word in neonatale intensiewe sorgeenhede, opleidingsinstansies sowel as die Suid-Afrikaanse Bloedoortappingsdiens. / Dissertation (MCur)--University of Pretoria, 2011. / Nursing Science / unrestricted

The present study starts from the premise that the academic formation has a strong influence in the development of critical thinking, clinical reasoning and in the decision making of the student of pharmacy. The objective of the study was to highlight what has been used for the development of critical thinking, clinical reasoning and decision making in pharmacy student training. Therefore, a systematic review was carried out. The studies were extracted from the databases: LILACS, PubMed / MEDLINE, Scopus, Web of Science. The words "Thinking", "Education pharmacy", "Students, Pharmacy", "Clinical decision-making" along with their terms of entry were used as descriptors. Two reviewers independently conducted the evaluation of titles, abstracts and articles in their entirety. The evaluation of methodological quality followed the quality checklist of a BEME (Best Evidence in Medical Education) research group. Of the 11 studies included, nine reached an expected quality index. The results of these studies indicated that pharmacy students when enrolled in pre-pharmacy, PharmD and undergraduate programs in four years in the North American context, or PharmD programs based on active methodologies in the Mexican and Saudi context can significantly improve some aspects / Scores of critical thinking of pharmacy students. Although positive results have been observed, further studies are needed, as the role of academic training in the development of critical thinking, and especially in the clinical thinking and decision-making of the pharmacy student, is not yet clear. However, the literature points to the need for curricular reformulation of undergraduate courses in pharmacy, geared to its multidimensional context, since curricular were identified primarily during performance improvement in critical thinking. / O presente estudo parte da premissa de que a formação acadêmica tem uma forte influência no desenvolvimento do pensamento crítico, raciocínio clínico e na tomada de decisões do estudante de farmácia. O objetivo do estudo foi diagnosticar o que vem sendo utilizado para o desenvolvimento do pensamento crítico, raciocínio clínico e tomado de decisão na formação do estudante de farmácia. Para tanto, foi realizada uma revisão sistemática. Os estudos foram extraídos das bases de dados: LILACS, PubMed/MEDLINE, Scopus, Web of Science. Como descritores foram utilizadas as palavras: “Thinking”, “Education pharmacy”, “Students, Pharmacy”, "Clinical decision-making" juntamente com seus termos de entrada. Dois revisores de forma independente conduziram a avaliação dos títulos, resumos e artigos na íntegra. A avaliação da qualidade metodológica seguiu o cheklist de qualidade de um grupo de pesquisa BEME (Best Evidence in Medical Education). Dos 11 estudos incluídos, nove atingiram um índice de qualidade esperado. Os resultados destes estudos apontaram que os estudantes de farmácia quando inseridos em programas de pre-pharmacy, PharmD de graduação em quatro anos no contexto norte-americano, ou em programas PharmD baseados em metodologias ativa no contexto mexicano e saudita pode melhorar significativamente alguns aspectos/escores do pensamento crítico de estudantes de farmácia. Embora tenham sido observados resultados positivos outros estudos são necessários, uma vez que ainda não está claro o papel da formação acadêmica no desenvolvimento do pensamento crítico, e principalmente do raciocínio clínico e na tomada de decisões do estudante de farmácia. Entretanto, a literatura aponta para a necessidade de reformulação curricular dos cursos de graduação em farmácia, voltados a seu contexto multidimensional, uma vez que foram identificados primordialmente aspectos curriculares, durante a melhoria de desempenho no pensamento crítico. / São Cristóvão, SE

Cette recherche qualitative identifie le rôle de l’expérience face à l’intuition et à l’émotion dans la décision clinique de l’infirmière d’accueil et d’orientation des urgences hospitalières. La problématique du rôle triple de l’expérience sur le raisonnement, sur la nature et le contrôle du « ressenti » éprouvé dans le feu de l’action est étudiée au travers de l’influence de la posture de connaissance face à l’expérience induisant l’acquisition et l’usage de savoirs explicites et implicites (Dewey, 2004) agissant sur le modèle opératif de pensée d’un professionnel (Pastré, 2011). La méthodologie, orientée par une posture théorique multi référentielle (Ardoino,1986), articule les approches de la décision en économie (Simon, 1983), en neurosciences (Berthoz, 2003 ; Damasio, 1995) avec les travaux sur l’intuition dans la pensée bi-systémique (Kahneman, 2016) et les approches du rôle cognitif des émotions (Livet, 2002 ; Rimé, 2009, Thievenaz, 2017). Des entretiens semi-directifs et d’explicitation (Vermersch, 1994) sont conduits auprès de vingt infirmiers-ères, de deux hôpitaux.Six propositions théoriques émanent des résultats. L’existence d’une posture « cognitivo-émotionnelle » face à l’expérience vécue dans l’action est découverte. Elle génère un mode et des modalités de raisonnement et d’élaboration d’indicateurs cliniques ou de savoirs d’action mais aussi un mode décisionnel à partir du vécu de l’expérience. Elle influence la nature « ressenti » qui est intuition ou émotion ou étonnement. Selon sa posture, l’infirmière cherche à confirmer son intuition. Elle cherche des preuves à son étonnement, régule son émotion ou renonce à prendre une décision, ou se protège de tout « ressenti ». / This doctoral thesis’ research identifies the roles of experience in the effects of intuition or emotion and clinical reasoning and characterizes the nature of the “feeling” rising; The “multiréférentiel” (Ardoino, 1986)theoretical and methodological framework links a pragmatist understanding of implicit or explicit experiential learning’s through an active or passive knowing posture (Dewey, 2004) with theoretical works concerning the decision processing in economics (Simon, 1983), in neurosciences (Berthoz, 2003; Damasio, 1995) and with the cognitive function of emotion (Livet, 2002;Rimé, 2009). Intuition is replaced in dual process theories of cognition (Kahneman, 2016). Data were collected from two French Parisian emergency’s departments through twenty emergency nurses differently experienced in triage, volunteered to take part in the study,. Semistructured interview collected the nurses’posture of knowing. “Elicitation interviews’” (Vermersch, 1994)recalled nurses’ thinking procedures in the heat of the moment and shows how nurses’ control their “feeling” and the set of the contextual determinants. Six theoretical propositions derived from the findings. During the patient’s examination and the clinical reasoning process, nurses adopt a particular “cognitive – emotional”posture of knowing and reflective thinking. This posture has an impact on the control of the nurse’s feeling andof the nature of what she felt and on the decision type. Depending of her posture, nurses will take into account her “feeling” or not. A negative emotion stops the decision making process. Intuition involves the search of additional fact or clues or clinical signs. The cognitive uncertainty induces a specific inquiry. The nurses’ “feeling’’ empirically characterize is an intuition, an emotion, an uncertainty.