his study discusses the benefits of Popular Participatory Theatre (PPT) as a research method with which to investigate the culture of silence around HIV/AIDS issues in Malealea Valley, Lesotho. Popular Participatory Theatre provided the means by which the community named, reflected on and initiated action with regard to their problems. This research will contribute to the growing body of research which aims to uncover effective modes of communication which could lead to behaviour change. This study employed the qualitative research methodology. This was in recognition that qualitative research involves in-depth understanding of human behaviours and the reasons that govern that behaviour, and looks at the reasons behind various aspects of behaviour, perceptions, beliefs and attitudes. Qualitative research seeks meaning rather than generality and contributes to theory development (Miller et al, 2003:192-3). In-depth interviews and focus groups were also used as instruments for data collection. The findings of the study indicate that socio-economic issues such as language, cultural practices, the way that Basotho are brought up and power dynamics around patriarchy contribute to the culture of silence. The Malealea Theatre Project helped the Malealea community to re-examine some of their beliefs and cultural practices. The findings also indicate that popular participatory theatre is an effective research method that can be used to collect data while also leading to community action. / Thesis (M.A.)-University of KwaZulu-Natal, Durban, 2008.

HIV / AIDS in the South African present context remains fraught with obstacles and challenges. The previous regime's willingness to turn a blind eye to the problem, combined with the present government's confused response has accelerated the disease and it's devastating impact to pandemic proportions. This has placed additional pressure on other sectors to respond. While civil society challenges government's delaying tactics and seeks to ease the plight of those living with HIV, the business sector is being called upon to act, in the interests of the stability of the national economy and it's own survival. Business is identified, locally and abroad, as the most relevant environment for intervention because of it's unique capacity to impact on both the workforce and the consumer market simultaneously. Business however exists for the purpose of making a profit. This is in itself an area of study that requires investigation: how does business meet the pressure to 'do the right thing' and protect its own best interests? This study will consider how some businesses have shifted the burden of AIDS, while others have prepared to meet the costs associated with implementing any interventions. The primary objective of this study is to investigate the impact of HIV / AIDS on the business sector with an assessment of the risk faced by business in the immediate and long-term. It further seeks to analyse business's current response in the context of international best practice standards. Case studies of Workplace HIV / AIDS Programmes are used to identify and analyse successful interventions that may be utilised in the South African context. While there are a few outstanding examples of workplace interventions being implemented in South Africa, there is some concern that too many companies are processing HIV / AIDS as a paper exercise without the commitment and care required for change. The impact of the disease on a physical level is compounded by stigmatization and fear. Issues of discrimination and intolerance permeate the environment in which employers are required to implement programmes that shift knowledge, attitudes and behaviour around HIV / AIDS. The secondary objective of this study is to test the emerging hypothesis that the face-to-face or one-on-one intervention is the most effective in successfully changing knowledge and attitudes about HIV / AIDS and can therefore influence a long-term change in behaviour. This study seeks to provide guidelines and recommendation for companies willing to implement HIV / AIDS workplace interventions by presenting an overview of the options available and indicating where best to invest limited resources. While the nature and scope of the study is by no means conclusive and remains open to ongoing social and medical research, it remains relevant in that it is placed in the context of timeless best practice. / Thesis (M.B.A.)-University of Natal, Durban, 2003.

This study sought to investigate the role of church leaders in the prevention and management of HIV and AIDS in the Sweetwaters community. In terms of HIV and AIDS South Africa is the most affected country in sub-Saharan Africa with KwaZulu-Natal as the epicenter of the pandemic. Therefore it is against this backdrop that the researcher articulates the management and leadership roles of church leaders in the prevention of HIV and AIDS as the center of this study. It is imperative that church pastors equip among themselves in order for them to have a significant effect in addressing HIV and AIDS issues in a context like the Sweetwaters community, for example. Church leaders are strategically positioned to play a central role in the combat against the pandemic within their churches and communities. This study has been undertaken using questionnaires and focus group studies with ten church leaders from Sweetwaters the community. The research seeks to: (a) gain a understanding of challenges confronting church leaders; (b) understand how they can tackle this challenge effectively as regards their leadership role. The above mentioned is summed up in the main research question of the study, which is formulated as follows: How do the church leaders understand and respond to their leadership role within their churches and the community in the supervision of a diversity of issues arising from the pandemic. The study pointed out that the involvement of church leaders in the prevention of HIV and AIDS is generally limited to spiritual and relief work. The only structured program available to the particular local churches, and which has been implemented, is to care for orphans. The position taken in this study is that there is a need for church leaders to develop modern realistic HIV and AIDS educational programs and to train their church members to engage in HIV and AIDS issue. / Thesis (M.Com.)-University of KwaZulu-Natal, Westville, 2010.

A human safe, Alhydrogel adjuvanted whole cell Trichomonas vaginalis vaccine was tested for efficacy in a BALB/c mouse model of vaginal infection. Additionally, the systemic and local immune response were measured. Vaccination reduced incidence and increased clearance of infection, and induced both systemic and local humoral immune responses. CD4+ cells were detected in vaginal tissues following intravaginal challenge with T. vaginalis, but were not seen in uninfected mice. CD4+ cells were detected more often, earlier, and in greater numbers in vaccinated vaginal tissues compared to unvaccinated controls. Presence of CD4+ T cells following infection can have significant implications of increasing HIV susceptibility and transmission. These data suggest that the vaccine induces local and systemic immune responses, and confers significantly greater protection against vaginal challenge than unvaccinated vaginal challenge. These data support the potential for a human vaccine against T. vaginalis infection that could also impact the incidence of HIV infections.

A presente Tese, situada na linha de pesquisa dos Estudos Culturais em Educação e utilizando-se do referencial teórico de Michel Foucault, constitui-se em um estudo sobre artefatos escolares que se destinam a ensinar maneiras de ser saudável, na atualidade. Para tanto, foram analisadas as cinco publicações das Agendas de Saúde Escolar correspondentes aos anos de 2007, 2008, 2009, 2010 e 2011 e as edições de 2009, 2010 e 2011 das Gincanas Solidárias, bem como os blogs de duas escolas participantes das atividades propostas nessas Gincanas. Tanto as Agendas de Saúde Escolar como as Gincanas Solidárias são projetos divulgados e efetivados na rede municipal de ensino de Porto Alegre/RS, sendo o projeto das Agendas oriundo do Programa Nacional de Saúde Escolar e o projeto das Gincanas uma proposta da própria Secretaria Municipal de Educação de Porto Alegre. O estudo procurou evidenciar como determinados discursos sobre saúde são colocados em evidência e ensinam os sujeitos a serem saudáveis através de máximas, slogans, orientações, poesias, textos informativos bem como desenhos e fotos produzidos, em sua grande parte, por alunos/as de escolas municipais participantes dos projetos. Entende-se, nesta tese, que as relações estabelecidas entre as diferentes enunciações presentes nos artefatos conferem às Agendas e às Gincanas a função de produtoras de uma cultura da saúde escolar, pois essas se inserem através de suas enunciações, discursos e práticas no contexto curricular, estabelecendo relações de poder-saber entre os diferentes sujeitos que organizam, participam e utilizam esses artefatos. Foi problematizado o modo como o material pesquisado age como uma forma de biopolítica voltada para a saúde escolar, operando modos peculiares de gerenciamento da população em relação ao alcance de uma vida saudável. O conceito de performatividade foi abordado como um eixo de análise a partir do qual se colocaram em articulação significados atribuídos à saúde que circulam no currículo e se direcionam à produção de práticas, bem como ao posicionamento dos sujeitos escolares. Foi possível perceber que as discussões contemporâneas sobre o binômio promoção da saúde/prevenção de doenças atravessam a organização dos materiais examinados, existindo, no entanto, um acento maior no cunho preventivo. Foi possível perceber, também, que na produção dos artefatos, há um viés moral e humanizador muito próximo dos discursos da pedagogia crítica, direcionado a condutas de saúde voltadas ao cuidado de si, dos outros e do meio ambiente. É importante considerar que os discursos presentes nos artefatos examinados, bem como os que circulam no currículo através das práticas que tais artefatos produzem, convocam alunos/as, professores/as e comunidade escolar em geral a assumirem condutas e hábitos considerados saudáveis e capazes de conduzir ao bem estar individual e coletivo. / The present thesis, situated on the Cultural Studies Education area, based on Michel Foucault`s theoretical references, constitutes a study on school artifacts that intend to teach ways of being healthy, presently. For such, it has been analyzed the five publications of the School Health Agendas, corresponding to the years of 2007, 2008, 2009, 2010 and 2011, and the editions of 2009, 2010 and 2011 of the Supportive Gymkhanas, as well as the blogs of two participant schools in those gymkhanas. Both School Health Agendas and Supportive Gymkhanas are projects divulged and carried out by the municipal school administration of Porto Alegre/RS, coming from the National Program for School Health. As for the Gymkhanas Project, they are a proposal of the Municipal Education Department of Porto Alegre. The study aimed to point the ways determined discourses about health are put on evidence and teach subject how to be health though maxims, slogans, orientations, poetry, informative texts as well as drawings and photos produced, in their majority, by students from the municipal schools that take part in the project. It is understood in this research that the relationships established among the different enunciations present in the artifacts grant the Agendas and the Gymkhanas the function of producers of a culture of school health, for they introduce themselves through enunciations, discourses and practices in the curricular context curricular, establishing relationships of power-knowledge among the different subjects that organize, take part and utilize such artifacts. It is discussed the way the researched material acts as a form of biopolitics turned to school health, operating peculiar means of managing the population in what regards to a healthy life. The concept of performativity was approached as a point of analysis from which meanings attributed to health that appear in the curriculum were put together for understanding how they directed to the production of practices as well as the positioning of school subjects. It has been possible to note that the contemporary discussions on the binomial health promotion/prevention of disease permeate the examined material. Notwithstanding, it has been observed that it is given more emphasis on the prevention aspect. Besides, it was observed that in the production of the artifacts there is a moral and humanizing bias that approaches the critical pedagogy, directed to heath conducts turned to the self, the others and the environmental care. It is important to consider that the discourses present on the researched artifacts, as well as those that circulated on the curriculum through the practices which such practices produce, convene students, teachers and the school community in a general basis to take on conducts and habits considered healthy and capable of leading to individual e collective well-being.

A presente Tese, situada na linha de pesquisa dos Estudos Culturais em Educação e utilizando-se do referencial teórico de Michel Foucault, constitui-se em um estudo sobre artefatos escolares que se destinam a ensinar maneiras de ser saudável, na atualidade. Para tanto, foram analisadas as cinco publicações das Agendas de Saúde Escolar correspondentes aos anos de 2007, 2008, 2009, 2010 e 2011 e as edições de 2009, 2010 e 2011 das Gincanas Solidárias, bem como os blogs de duas escolas participantes das atividades propostas nessas Gincanas. Tanto as Agendas de Saúde Escolar como as Gincanas Solidárias são projetos divulgados e efetivados na rede municipal de ensino de Porto Alegre/RS, sendo o projeto das Agendas oriundo do Programa Nacional de Saúde Escolar e o projeto das Gincanas uma proposta da própria Secretaria Municipal de Educação de Porto Alegre. O estudo procurou evidenciar como determinados discursos sobre saúde são colocados em evidência e ensinam os sujeitos a serem saudáveis através de máximas, slogans, orientações, poesias, textos informativos bem como desenhos e fotos produzidos, em sua grande parte, por alunos/as de escolas municipais participantes dos projetos. Entende-se, nesta tese, que as relações estabelecidas entre as diferentes enunciações presentes nos artefatos conferem às Agendas e às Gincanas a função de produtoras de uma cultura da saúde escolar, pois essas se inserem através de suas enunciações, discursos e práticas no contexto curricular, estabelecendo relações de poder-saber entre os diferentes sujeitos que organizam, participam e utilizam esses artefatos. Foi problematizado o modo como o material pesquisado age como uma forma de biopolítica voltada para a saúde escolar, operando modos peculiares de gerenciamento da população em relação ao alcance de uma vida saudável. O conceito de performatividade foi abordado como um eixo de análise a partir do qual se colocaram em articulação significados atribuídos à saúde que circulam no currículo e se direcionam à produção de práticas, bem como ao posicionamento dos sujeitos escolares. Foi possível perceber que as discussões contemporâneas sobre o binômio promoção da saúde/prevenção de doenças atravessam a organização dos materiais examinados, existindo, no entanto, um acento maior no cunho preventivo. Foi possível perceber, também, que na produção dos artefatos, há um viés moral e humanizador muito próximo dos discursos da pedagogia crítica, direcionado a condutas de saúde voltadas ao cuidado de si, dos outros e do meio ambiente. É importante considerar que os discursos presentes nos artefatos examinados, bem como os que circulam no currículo através das práticas que tais artefatos produzem, convocam alunos/as, professores/as e comunidade escolar em geral a assumirem condutas e hábitos considerados saudáveis e capazes de conduzir ao bem estar individual e coletivo. / The present thesis, situated on the Cultural Studies Education area, based on Michel Foucault`s theoretical references, constitutes a study on school artifacts that intend to teach ways of being healthy, presently. For such, it has been analyzed the five publications of the School Health Agendas, corresponding to the years of 2007, 2008, 2009, 2010 and 2011, and the editions of 2009, 2010 and 2011 of the Supportive Gymkhanas, as well as the blogs of two participant schools in those gymkhanas. Both School Health Agendas and Supportive Gymkhanas are projects divulged and carried out by the municipal school administration of Porto Alegre/RS, coming from the National Program for School Health. As for the Gymkhanas Project, they are a proposal of the Municipal Education Department of Porto Alegre. The study aimed to point the ways determined discourses about health are put on evidence and teach subject how to be health though maxims, slogans, orientations, poetry, informative texts as well as drawings and photos produced, in their majority, by students from the municipal schools that take part in the project. It is understood in this research that the relationships established among the different enunciations present in the artifacts grant the Agendas and the Gymkhanas the function of producers of a culture of school health, for they introduce themselves through enunciations, discourses and practices in the curricular context curricular, establishing relationships of power-knowledge among the different subjects that organize, take part and utilize such artifacts. It is discussed the way the researched material acts as a form of biopolitics turned to school health, operating peculiar means of managing the population in what regards to a healthy life. The concept of performativity was approached as a point of analysis from which meanings attributed to health that appear in the curriculum were put together for understanding how they directed to the production of practices as well as the positioning of school subjects. It has been possible to note that the contemporary discussions on the binomial health promotion/prevention of disease permeate the examined material. Notwithstanding, it has been observed that it is given more emphasis on the prevention aspect. Besides, it was observed that in the production of the artifacts there is a moral and humanizing bias that approaches the critical pedagogy, directed to heath conducts turned to the self, the others and the environmental care. It is important to consider that the discourses present on the researched artifacts, as well as those that circulated on the curriculum through the practices which such practices produce, convene students, teachers and the school community in a general basis to take on conducts and habits considered healthy and capable of leading to individual e collective well-being.

A presente Tese, situada na linha de pesquisa dos Estudos Culturais em Educação e utilizando-se do referencial teórico de Michel Foucault, constitui-se em um estudo sobre artefatos escolares que se destinam a ensinar maneiras de ser saudável, na atualidade. Para tanto, foram analisadas as cinco publicações das Agendas de Saúde Escolar correspondentes aos anos de 2007, 2008, 2009, 2010 e 2011 e as edições de 2009, 2010 e 2011 das Gincanas Solidárias, bem como os blogs de duas escolas participantes das atividades propostas nessas Gincanas. Tanto as Agendas de Saúde Escolar como as Gincanas Solidárias são projetos divulgados e efetivados na rede municipal de ensino de Porto Alegre/RS, sendo o projeto das Agendas oriundo do Programa Nacional de Saúde Escolar e o projeto das Gincanas uma proposta da própria Secretaria Municipal de Educação de Porto Alegre. O estudo procurou evidenciar como determinados discursos sobre saúde são colocados em evidência e ensinam os sujeitos a serem saudáveis através de máximas, slogans, orientações, poesias, textos informativos bem como desenhos e fotos produzidos, em sua grande parte, por alunos/as de escolas municipais participantes dos projetos. Entende-se, nesta tese, que as relações estabelecidas entre as diferentes enunciações presentes nos artefatos conferem às Agendas e às Gincanas a função de produtoras de uma cultura da saúde escolar, pois essas se inserem através de suas enunciações, discursos e práticas no contexto curricular, estabelecendo relações de poder-saber entre os diferentes sujeitos que organizam, participam e utilizam esses artefatos. Foi problematizado o modo como o material pesquisado age como uma forma de biopolítica voltada para a saúde escolar, operando modos peculiares de gerenciamento da população em relação ao alcance de uma vida saudável. O conceito de performatividade foi abordado como um eixo de análise a partir do qual se colocaram em articulação significados atribuídos à saúde que circulam no currículo e se direcionam à produção de práticas, bem como ao posicionamento dos sujeitos escolares. Foi possível perceber que as discussões contemporâneas sobre o binômio promoção da saúde/prevenção de doenças atravessam a organização dos materiais examinados, existindo, no entanto, um acento maior no cunho preventivo. Foi possível perceber, também, que na produção dos artefatos, há um viés moral e humanizador muito próximo dos discursos da pedagogia crítica, direcionado a condutas de saúde voltadas ao cuidado de si, dos outros e do meio ambiente. É importante considerar que os discursos presentes nos artefatos examinados, bem como os que circulam no currículo através das práticas que tais artefatos produzem, convocam alunos/as, professores/as e comunidade escolar em geral a assumirem condutas e hábitos considerados saudáveis e capazes de conduzir ao bem estar individual e coletivo. / The present thesis, situated on the Cultural Studies Education area, based on Michel Foucault`s theoretical references, constitutes a study on school artifacts that intend to teach ways of being healthy, presently. For such, it has been analyzed the five publications of the School Health Agendas, corresponding to the years of 2007, 2008, 2009, 2010 and 2011, and the editions of 2009, 2010 and 2011 of the Supportive Gymkhanas, as well as the blogs of two participant schools in those gymkhanas. Both School Health Agendas and Supportive Gymkhanas are projects divulged and carried out by the municipal school administration of Porto Alegre/RS, coming from the National Program for School Health. As for the Gymkhanas Project, they are a proposal of the Municipal Education Department of Porto Alegre. The study aimed to point the ways determined discourses about health are put on evidence and teach subject how to be health though maxims, slogans, orientations, poetry, informative texts as well as drawings and photos produced, in their majority, by students from the municipal schools that take part in the project. It is understood in this research that the relationships established among the different enunciations present in the artifacts grant the Agendas and the Gymkhanas the function of producers of a culture of school health, for they introduce themselves through enunciations, discourses and practices in the curricular context curricular, establishing relationships of power-knowledge among the different subjects that organize, take part and utilize such artifacts. It is discussed the way the researched material acts as a form of biopolitics turned to school health, operating peculiar means of managing the population in what regards to a healthy life. The concept of performativity was approached as a point of analysis from which meanings attributed to health that appear in the curriculum were put together for understanding how they directed to the production of practices as well as the positioning of school subjects. It has been possible to note that the contemporary discussions on the binomial health promotion/prevention of disease permeate the examined material. Notwithstanding, it has been observed that it is given more emphasis on the prevention aspect. Besides, it was observed that in the production of the artifacts there is a moral and humanizing bias that approaches the critical pedagogy, directed to heath conducts turned to the self, the others and the environmental care. It is important to consider that the discourses present on the researched artifacts, as well as those that circulated on the curriculum through the practices which such practices produce, convene students, teachers and the school community in a general basis to take on conducts and habits considered healthy and capable of leading to individual e collective well-being.

Submitted by Mario BC (mario@bc.ufrpe.br) on 2017-04-26T12:32:52Z No. of bitstreams: 1 Thiago Arcoverde Maciel.pdf: 2765936 bytes, checksum: b2a040b8c8b92a2259f8f141af305868 (MD5) / Made available in DSpace on 2017-04-26T12:32:52Z (GMT). No. of bitstreams: 1 Thiago Arcoverde Maciel.pdf: 2765936 bytes, checksum: b2a040b8c8b92a2259f8f141af305868 (MD5) Previous issue date: 2015-02-27 / Conselho Nacional de Pesquisa e Desenvolvimento Científico e Tecnológico - CNPq / Urolithiasis is a metabolic disease of complex and multifactorial etiology, characterized by uroliths formation in the urinary system. It becomes clinically important when obstruction occurs, with little chance of reversal, and prevention is the best option for maintaining the integrity of the reproductive capacity. For this, one must know the biochemical profile of animals and fix the possible factors that may be related to the formation of uroliths. Morphometric study in turn, enables the comparative observation and description of changes and can therefore be used as a method of diagnostic. Urinary acidification is cited as an efficient alternative for the prevention, so vitamin C was used. In this study, 20 healthy sheep, male (not neutered), Santa Ines breed, aged approximately 90 days, were divided into three groups (G1 n=7 - calculogenic diet without vitamin C, G2 n=7 - calculogenic diet with vitamin C and G3 n=6 - control). To analyze the biochemical profiles groups 1 and 2 were compared and the morphometric analysis the three groups were compared. Animals were examined weekly, allowing direct observation of clinical signs, such as prostration/restlessness, penile exposure, abdomen kicking, urethral process congestion, among others. Analysis of biochemical profiles of urine and serum revealed hyperproteinemia (8.99g/dL) and proteinuria (43.82g/dL) in 57.14% aciduria (G1) and 71.43% (G2) and the presence of erythrocytes, leukocytes, bacteria and sperm to the urinary sediment. There was an important increase of phosphorus and magnesium e there was a substantial decrease of calcium which was present in 50% of uroliths samples analyzed. At the end of the experimental time animals were slaughtered and necropsy of them was followed by morphometry of the organs of the urinary system. Necrosis of urethral process and bladder with extensive bleeding area were observed during the necropsy procedure. The width of the kidneys and ureters were higher in G2, which may have contributed to lower retention of uroliths on this site. / Urolitíase é uma doença metabólica de etiologia complexa e multifatorial, caracterizada pela formação de urólitos no sistema urinário. Torna-se clinicamente importante quando ocorre obstrução, havendo poucas chances de reversão do quadro, sendo a prevenção a melhor opção para manutenção da capacidade reprodutiva. Para isso, deve-se conhecer o perfil bioquímico dos animais e corrigir os possíveis fatores que estão relacionados à formação dos urólitos. O estudo morfométrico por sua vez, possibilita a observação comparativa e descrição de alterações podendo ser empregado como método de auxílio diagnóstico. A acidificação urinária é citada como alternativa eficiente para a prevenção, por isso a vitamina C foi utilizada. Nesse estudo foram utilizados 20 ovinos hígidos, da raça Santa Inês, machos (não castrados), com idade aproximada de 90 dias, distribuídos em três grupos (G1 n=7 – dieta calculogênica sem vitamina C, G2 n=7 – dieta calculogênica com vitamina C e G3 n=6 – controle). Para análise dos perfis bioquímicos foram confrontados os grupos 1 e 2, e para a morfometria foram comparados os três grupos. Os animais foram examinados semanalmente, permitindo a imediata observação dos sinais clínicos, como prostração/inquietação, exposição peniana, escoiceamento do abdômen, congestão de processo uretral. A bioquímica sérica e urinária revelou hiperproteinemia (8,99g/dL) e proteinúria (4,38g/dL), acidúria em 57,14% (G1) e 71,43% (G2) e presença de hemácias, leucócitos, bactérias e espermatozóides ao exame do sedimento urinário. Houve elevação expressiva do fósforo e do magnésio e diminuição substancial do cálcio que esteve presente em 50% das amostras de urólitos analisadas. Ao término do experimento foi realizado o abate e necropsia dos animais seguindo-se a morfometria dos órgãos do sistema urinário. Necrose de processo uretral e bexiga repleta com extensa área de hemorragia foram observados durante necropsia. Os rins e ureteres apresentaram valores morfométricos distintos entre os grupos, sendo maiores no G2, o que pode ter contribuído para uma menor retenção de cálculos neste local.

Este estudo avaliou in situ a ação do gel contendo euclea natalensis na redução da erosão associada ou não abrasão em esmalte e dentina humanos. O estudo foi realizado em duas fases cruzadas de cinco dias cada (SG - sem gel e CG - com gel) nas quais 10 voluntários utilizaram placas palatinas com 4 blocos de esmalte e 4 blocos de dentina, distribuídos em duas fileiras horizontais contendo 4 blocos, correspondendo aos subgrupos: erosão (Eros); erosão + abrasão (30min) (Eros + Abras). Em fases alternadas metade dos voluntários teve a aplicação do gel em todos espécimes do aparelho e na outra metade os espécimes não sofreram tratamento nenhum. O gel foi aplicado durante 5 minutos, sendo o mesmo removido após este tempo. Na etapa experimental os aparelhos foram imersos em refrigerante 4x ao dia, por 5 minutos. A seguir o aparelho foi colocado na boca por 30 minutos. Após este período os voluntários escovaram 4 espécimes da fileira Eros + Abras e recolocaram o aparelho. A outra fileira (Eros) não foi escovada. A análise da perda de estrutura dentária foi realizada por meio de teste de perfilometria e microdureza. Foi utilizada a análise de variância (ANOVA) a 2 critérios (presença ou ausência da aplicação do gel) de acordo com cada substrato e o teste TUCKEY (p<0,05). Não houve associação entre perda de dureza e condições ou grupos testados (p>0,05). O desgaste dentário médio nos blocos de esmalte para o grupo CG foi de 12,86µm eros e 12,13µm eros+abras e para os blocos de dentina foi de 5,95µm eros e 6,16µm eros+abras. A média de desgaste dentário para o grupo SG, em blocos de esmalte foi de 14,08µm eros e 16,29µm eros+abras e, nos blocos de dentina foi de 13,64µm eros e 12,63µm eros+abras. Houve diferença significativa entre os grupos (p<0,05). Concluiu-se que o gel contendo euclea natalensis é capaz de reduzir o desgaste associado ou não a abrasão, independente do tipo de substrato, esmalte ou dentina. / This study investigated the action of in situ gel containing euclea natalensis on reducing erosion associated or not with abrasion in the human enamel and dentin. The study was performed into two phases crossed in five days each (WOG-without gel and WG- with gel) in which ten volunteers used acrylic palatal appliances with four blocks of enamel and four dentin, distributed in two horizontal rows containing four blocks, corresponding to the subgroups: erosion (Eros); erosion + abrasion (30min) (Eros + Abras). In alternating phases half the volunteers had the applying the gel at all specimens. And the other half of the volunteers have not suffered any treatment. The gel was applied during 5 minutes, being removed after this time. In stage experimental, the blocks were subjected to erosion by immersion of the appliances into soft drink for five minutes, 4 times a day. The appliance was then replaced into the mouth for 30 minutes. After this period the volunteers brushed row (eros+abrasion) and replaced into the mouth. The row (eros) was not brushed. The analysis of the dental structure were determined using profilometry and microhardness tests. ANOVA by two criteria (presence or absence of application of gel) in agreement with each the substrate and Tukey test were applied (p <0.05). Microhardness and conditions or groups tested were not found association (p> 0.05). The mean wear in enamel blocks was 12.86µm eros and 12.13µm eros + abras in the WG group and in dentin blocks was 5.95 µm eros and 6.16µm eros+ abras. The mean wear in enamel blocks was 14.08µm eros and 16.29µm eros+abras for the WOG group and in dentin blocks was 13.64µm eros and 12.63µm eros + abras. There was significant difference between groups (p <0.05). It concluded that the gel containing Euclea Natalensis can reduce erosion with or without abrasion, independently of the substrate type, enamel or dentin.

D.Phil. (Biokinetics) / Please refer to full text to view abstract