O trabalho, composto por dois artigos, tem como tema a dimensão social da integração regional, caracterizada pela relação entre direitos sociais e interesses comerciais, com foco no caso do Mercosul. O primeiro artigo realiza uma revisão bibliográfica, sistematizando-a em duas grandes linhas de estudo. Primeiramente, a relação entre comércio e direitos humanos, em particular o direito à saúde, e o potencial da integração regional para a sua efetivação. Em segundo lugar, as interpretações sobre a evolução institucional e conceitual da dimensão social do Mercosul. O segundo artigo apresenta os resultados do estudo empírico do caso das normas do Mercosul-Saúde, orientado pela hipótese de que, em consonância com uma suposta mudança de paradigma, as normas sanitárias teriam migrado da eliminação de barreiras ao livre comércio para a proposição de políticas integradas tendentes a dar efetividade ao direito à saúde dos cidadãos mercosulinos. / This work, consisting of two articles, has as its main theme the social dimension of regional integration, characterized by the relationship between social rights and commercial interests, focusing on the case of Mercosur. The first article conducts a review of the literature, systematizing two main lines of study. Firstly, the relationship between trade and human rights, especially the right to health, and the potential of regional integration for its effectiveness. Secondly, the interpretations of the institutional and conceptual evolution of the social dimension of Mercosur. The second article presents the results of a empirical study of Mercosur\'s health standards, based on the hypothesis that, in line with a supposed paradigm shift, they have migrated from the elimination of barriers to liberalize trade to the proposition of integrated policies to give effectiveness to the right to health of Mercosur\'s citizens.

The thesis describes surface topography of a-CSi:H films deposited by continuous wave plasma enhanced chemical vapor deposition (PECVD) based on tetravinylsilane monomer (TVS). Thin films are completely used in many fields of modern technologies and their physical and mechanical properties are affected by thin film preparation techniques. In this thesis the thin films were deposited by PECVD method on silicon wafers with the pure TVS monomer. Deposited samples were topographically described and analyzed using atomic force microscopy (AFM). The main characteristics which were described are RMS roughness, autocorrelation function and a size distribution of grains on the thin film surface. Analysis was realized with two sets of samples with different powers and thickness. The main results were statistically evaluated like a mixture of object on the surface prepared in different deposition conditions.

The purpose of this study is to investigate if individual differences exists between microwave sensors from the same manufacturer and to find which variables of the microwave sensors that can be the reason for those individual differences. To investigate this, an experiment environment was made to gather data from microwave sensors in a repetitive way. This experiment environment was used in three different experiments where individual differences, radiation pattern and noise were measured. As a base for the experiments a literature review was made to find variables that could affect the individual differences. The study shows that individual differences on signal strength can be found on microwave sensors of the type MDU2000 from Microwave solutions. Also, the radiation pattern at higher angles can differentiate. The frequency from the microwave sensors at lower speeds shows no significant difference individually. This study contributes to increased knowledge about individual differences on microwave sensors of the type MDU2000. Results from this study can be used as a recommendation to suitable applications. As both resources and time have been limited during this thesis, the study was limited to only perform tests on microwave sensors of the type doppler radar. Another limit to the study is to only do tests at lower speeds i.e. a maximum speed of 5km/h. / Syftet med denna studie är utreda om individuella skillnader finns mellan mikrovågssensorer från samma tillverkare samt att ta reda på vilka variabler hos mikrovågssensorerna som kan bidra till dessa individuella skillnader. För att ta reda på detta konstruerades en experimentmiljö för att samla in data från mikrovågssensorer på ett repetitivt sätt. Denna experimentmiljö användes i tre olika experiment där individuell skillnad, strålningsmönstret samt brus uppmättes. Som grund till experimenten utfördes en litteraturundersökning för att hitta variabler som kan påverka den individuella skillnaden. Studien visar att individuella skillnader på signalstyrka finns bland mikrovågssensorer av typen MDU2000 från Microwave solutions. Även antennens strålningsmönster vid större vinklar kan skilja. Frekvensen från mikrovågssensorn vid lägre hastigheter visar ingen signifikant skillnad individuellt. Denna studie bidrar till ökad kunskap kring individuella skillnader på mikrovågssensorer av typen MDU2000. Resultat från studien kan användas som rekommendation till lämpliga användningsområden. Då både resurser och tid har varit begränsade under examensarbetet sattes en begränsning till att endast utföra tester på mikrovågssensorer av typen dopplerradar. En till begränsning är att endast göra tester på låga hastigheter d.v.s. maximalt 5km/h.

<p>Soft tissue sarcomas (STSs) are a heterogeneous group of mesenchymal tumors comprised of >70 subtypes. An important question is how the cell of origin and the pathways to tumor development shape the broad array of STS subtypes. By forcing identical tumor-promoting mutations to different cell types in Genetically Engineered Mouse Models (GEMMs) of STS, I have a unique model system to investigate this question. In the process of performing these experiments I observed that genetic mutations are necessary, but not sufficient for rapid sarcoma formation. However, tissue injury dramatically accelerates sarcoma formation in our GEMM of STS. For my thesis, I have worked to understand how cell of origin affects sarcoma subtype and how the microenvironment in our models promotes transformation. I have observed that cell of origin plays an important, but not the only, role in defining STS subtype. Additionally, I have concluded that the microenvironment, and specifically the HGF/c-MET signaling pathway play a crucial role in promoting sarcoma development after acute tissue injury.</p> / Dissertation

The mobility that wireless communication offers to users, added to the ease of installation have increased the demand on such communication systems. However, the main drawback of wireless communication is the degradation of the signal as it travels through the channel due to the different propagation mechanisms the signal undergoes. To minimise the effect of the channel and get the best service, the base stations must be appropriately located within the environment. This requires proper knowledge of the channel characteristics. Ray tracing software is used throughout this work to generate the channel characteristics of an indoor environment. After getting the channel characteristics, a novel cost function is defined based on the path loss values and it is then optimised. Once the optimal base stations’ positions are found, the minimal amount of power required to cover a predefined percentage of the possible receivers’ locations is calculated. On the other hand, a receiver’s position acquiring enough field strength does not necessarily enjoy the service. This depends on the time dispersion parameters values relative to the symbol rate. The time dispersion parameters have always been ignored in the literature while finding the optimal base stations’ locations. Three cost functions that take into consideration both the path loss and rms delay spread, for the first time in the literature, are therefore defined. The cost functions are optimised and their corresponding results are compared. Furthermore, indoor environments have always been considered static which is never realistic. They are subject to continuous changes such as opening doors and windows as well as the presence of people. The first detailed analysis and quantified results of the effect of a dynamic environment on the optimal base stations’ positions and minimal emitted power are presented. It is shown that the optimal base stations’ locations and minimal emitted power are sensitive to such environment changes. The environment changes can also disturb the service for active receivers. Three techniques to overcome the effect of environment changes and bring the disturbed service back to receivers are proposed. The first two techniques rely on increasing the emitted power or changing the antenna polarisation. The third technique is a novel technique that gives the base station the ability to automatically move in various directions within a limited distance. The techniques are tested and their efficiency and limitations are discussed.

The Environmental Resource Mapping System (E-RMS) is a geographic information system (GIS) that is used by the National Parks and Wildlife Service to assist in management of national parks. The package is available commercially from the Service and is used by other government departments for environmental management. E-RMS has also been present in Australian Universities and used for academic work for a number of years. This thesis demonstrates that existing procedures for product quality and performance have not been followed in the production of the package and that the package and therefore much of the work undertaken with the package is fundamentally flawed. The E-RMS software contains and produces a number of serious mistakes. Several problems are identified and discussed in this thesis. As a result of the shortcomings, the author recommends that an enquiry be conducted to investigate *1/ The technical feasibility of each project for which the E-RMS package has been used; *2/ The full extent and consequences of the failings inherent with the package; and *3/ The suitability of the E-RMS GIS package for the purposes for which it is sold. Australian Standard 3898 requires that the purpose, functions and limitations of consumer software shall be described. To comply with this standard, users of the E-RMS package would have to be informed of several factors related to it. These are discussed in the research. Failure to consider the usefulness and extractable nature of information in any GIS database will inevitably lead to problems that may endanger the phenomena that the GIS is designed to protect. / Master of Applied Science (Environmental Science)

Les rhabdomyosarcomes embryonnaires et aléolaires (RMS) appartiennent aux tumeurs des tissus mous les plus fréquentes chez les enfants dont elles représentent 2/3 des cas. Plusieurs données suggèrent que la dérégulation des cellules progénitrices du muscle squelettique pourrait jouer un rôle dans l'émergence des cellules de RMS qui ont aussi bien perdu le contrôle de la régulation de la prolifération cellulaire que la capacité à se différencier.Néanmoins les mécanismes de développement des RMS restent à caractériser. La famille des IMPs et notamment IMP-2, protéines liant les ARN, sont à la fois fortement exprimées dans le muscle en régénération in vivo mais aussi dans les cellules de RMS.Au cours de ma thèse, j'ai pu mettre en évidence le rôle d'IMP-2 dans la motilité des cellules de RMS et dans les cellules musculaires ainsi que dans le contrôle de l'intégrité du cytosquelette de microtubules (MTs) et dans le remodelage des adhésions focales. En effet, IMP-2 est impliqué à la fois dans la régulation de l'expression de MuRF-3, une protéine lié àla stabilisation des MTs et de Pinch-2, un important médiateur de l'adhésion cellulaire.

At Flight and Systems test Saab AB, a post-processing software is used to process GPS data. A new software by the name GrafNav has been purchased and the purpose of this master thesis therefore became, partly to make a judgment regarding GrafNav’s ability to estimate position, velocity and accuracy, partly to if needed improve the estimate and finally find one or several methods to estimate the position and velocity accuracy. The judgment of GrafNav was performed partly by a comparison to the former post-processing software (PNAV) and partly by a comparison to the airplane’s inertial navigation system (INS). The experiments showed that GrafNav’s ability to estimate the position is comparable with PNAV:s, but its capacity to estimate the velocity is considerably worse. The velocity estimate even showed a more noisy behavior than the original velocity from the receiver. More effort is needed to judge GrafNav’s ability to estimate the accuracy thru its quality signals. A few trials were made to improve the velocity estimate thru Kalman filtering (Rauch-Tung-Striebel smoothing). The filtering was first made using only the position data from GrafNav as measurements and afterwards both position and velocity data from GrafNav was used. The outcome of the Kalman filtering showed that the best result is obtained when solely position data is used and that the estimate in general is comparable with PNAV:s estimate, but considerable big deviations is obtained in conjunction to interruptions in position data. More over, is more effort needed using both position and velocity data when performing the smoothing and also replacing the stationary Kalman filter with an adaptive filter. Finally a method was brought out to estimate the position precision and a method to estimate the velocity accuracy. Both methods use the INS velocity to perform an estimation.

In this report we focus on the use of an economical way on how Scalar Network Analyzer (SNA) works instead of Vector Network Analyzer (VNA) to estimate the phase angle of signals in indoor channel. This is detailed in RMS delay theory and simulation section, experimental is designed in the according Experiment Design section, where we also state the required measurements known from the math part. In our work, data are recorded both from two different channel characteristics. Method of achieving amplitude is by using deconvolution theory. The condition of applying Hilbert transform are highlighted as impulse response h(t) in time domain should be causal.  The recorded data amplitude is computed by Hilbert Transform, and therefore validate the condition using Inverse Discrete Fourier Transform (IDFT) back to time domain to achieve h(t). Power delay profile P(t) is therefore presented afterwards. In paper calculations of rms delay τrms  of the channel which is the most important variable are also performed, the results calculated from different windowing truncation and the LOS and NLOS characteristics are compared in discussion and conclusion section, it also includes Opinions of window functions chosen for the phase estimation.

<p>At Flight and Systems test Saab AB, a post-processing software is used to process GPS data. A new software by the name GrafNav has been purchased and the purpose of this master thesis therefore became, partly to make a judgment regarding GrafNav’s ability to estimate position, velocity and accuracy, partly to if needed improve the estimate and finally find one or several methods to estimate the position and velocity accuracy. </p><p>The judgment of GrafNav was performed partly by a comparison to the former post-processing software (PNAV) and partly by a comparison to the airplane’s inertial navigation system (INS). The experiments showed that GrafNav’s ability to estimate the position is comparable with PNAV:s, but its capacity to estimate the velocity is considerably worse. The velocity estimate even showed a more noisy behavior than the original velocity from the receiver. More effort is needed to judge GrafNav’s ability to estimate the accuracy thru its quality signals. </p><p>A few trials were made to improve the velocity estimate thru Kalman filtering (Rauch-Tung-Striebel smoothing). The filtering was first made using only the position data from GrafNav as measurements and afterwards both position and velocity data from GrafNav was used. The outcome of the Kalman filtering showed that the best result is obtained when solely position data is used and that the estimate in general is comparable with PNAV:s estimate, but considerable big deviations is obtained in conjunction to interruptions in position data. More over, is more effort needed using both position and velocity data when performing the smoothing and also replacing the stationary Kalman filter with an adaptive filter. </p><p>Finally a method was brought out to estimate the position precision and a method to estimate the velocity accuracy. Both methods use the INS velocity to perform an estimation.</p>