Made available in DSpace on 2015-08-19T13:52:55Z (GMT). No. of bitstreams: 2 13.pdf: 7121518 bytes, checksum: a7c8e7a7bd443ccd7df30b5090abf1e0 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2013 / Fundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos/Farmanguinhos. Rio de Janeiro, RJ, Brasil. / O presente estudo teve por objetivo investigar e avaliar a possível contribuição que a obrigatoriedade do registro de Insumos Farmacêuticos Ativos (IFAs), estabelecida pela Resolução da Diretoria Colegiada da ANVISA (RDC) n° 57/2009, a partir de 2010, teve no estabelecimento da isonomia regulatória entre o fabricante do IFA no Brasil e o fabricante internacional e que efetividade essa isonomia teve no restabelecimento da produção local de IFAs quando aliada à implementação de outras ações demandadas pela indústria farmoquímica brasileira, como a isonomia tributária, os incentivos fiscais, as parcerias para o desenvolvimento produtivo e o poder de compra do Estado. A pesquisa foi do tipo bibliográfica, documental e longitudinal. Constatou-se que, passados dois anos desde o início da exigência do registro de IFA, esta se mostrou efetiva na obtenção da isonomia regulatória. Porém, o tempo de análise não foi suficientemente longo para assegurar que a mesma, conjugada com outras ações do governo para o incentivo à produção local de IFAs, tenha sido capaz de promover o aumento, via substituição das importações desses produtos, apesar de haver sinalizações de que isso acontecerá. Como consequência espera-se que traga um aumento da produção do IFA e a redução da dependência do Brasil ao fornecimento externo, possibilitando o aumento da oferta interna desses insumos aos laboratórios farmacêuticos instalados no país, sejam eles públicos ou privados, além de melhorar a qualidade e o acesso dos medicamentos disponibilizados à sociedade brasileira. / The present study had as objectives to investigate and evaluate the possible contribution that the requirement of registration of Active Pharmaceutical Ingredients (APIs), established by the Resolução da Diretoria Colegiada of ANVISA Nr. 57/2009, as of 2010, had on the establishment of the regulatory isonomy between the producer of the API in Brazil and the international producer as well as the effectiveness this isonomy had in the reestablishment of the local production of APIs, when applied in parallel with the implementation of other actions demanded by the Brazilian pharmochemical industry, like the tax isonomy, the fiscal incentives, the partnerships for the productive development and the State buying power. The investigation involved bibliographic, documental and longitudinal analysis of the material available. It was concluded that, after two years since the beginning of the registration requirement, it turned out to be effective in bringing up the desired regulatory isonomy. However, the space of time used for the analysis was not sufficiently long to ensure that the registration, coupled with other governmental actions to promote the local production of APIs, could have been capable to promote the increase, via substitution of importations, of these products, although there are some signs that this will happen. As a consequence it is expected that it will bring an increase of the API production and the reduction of the Brazilian dependence of external supply, giving space to the internal offer of these products to the pharmaceutical laboratories located in Brazil, either public or private, besides improving the quality and the access of the medicines made available to the Brazilian society.

[pt] Esta tese nasceu da minha inserção profissional como assistente social em uma unidade de saúde de emergência do Estado do Rio de Janeiro - Hospital Estadual Carlos Chagas - HECC, onde encontrei várias crianças que não possuíam sua certidão de nascimento. O estranhamento que me causou este fato tornou-se maior ao perceber recorrências significativas desta situação e suas reverberações. Verifiquei que essas crianças eram chamadas pelos profissionais do HECC como Filho de acrescido do nome da mãe. Aos poucos compreendi que a ausência de certidão de nascimento se constitui em um fenômeno oficialmente denominado sub-registro de nascimento, a respeito do qual há pouca produção teórica, como pude verificar ao longo do processo de investigação. Tal problemática veio a ser a minha questão de pesquisa. Meu objetivo nesta tese foi entender porque algumas crianças atendidas no HECC, no período compreendido entre os anos de 1999 a 2007, não foram registradas. Buscando uma abordagem etnográfica, procurei desvendar as razões deste fato. Para tanto investiguei os significados da certidão de nascimento com mães e pais e suas implicações nas interações com as instituições escolares. Já que algumas crianças não foram registradas porque suas mães também não o foram, incorporei no processo de investigação adultos igualmente sem certidão de nascimento. Tal problemática me sugere uma questão instigante para o debate sobre o registro civil que envolve a reprodução social dos setores pobres da sociedade. Com este estudo, pretendo contribuir para a compreensão da história da infância e da família pobre brasileira, na expectativa de que esta investigação seja um alerta para os setores responsáveis pelo sistema de registro civil no Brasil. Ademais, pretendo contribuir para a elaboração de políticas públicas educacionais. Como instrumentos de trabalho, utilizei um questionário, entrevistas abertas, conversas com mães e pais, observações, documentos e material institucional do HECC. Meu diálogo central se deu com Roberto DaMatta (1997a; 1997; 2000), Ana Liési Thurler (2004); Cynthia Sarti (1996;2004) e Cláudia Fonseca (2005;no prelo). / [en] This paper is a consequence of my professional insertion as a social assistant in an emergency room unity of Rio de Janeiro State - Hospital Estadual Carlos Chagas - HECC, where I met several children who did not have a birth certificate. This fact surprised me even more when I realized the situation was significantly recurrent, as well as its reverberations. I noticed that these children were referenced by HECC staff as Child of, plus the name of their mothers. Slowly I understood that the birth certificate absence constitutes a phenomenon officially called birth under-registration, about what there is a few theoric production, as I could verify during the investigation process. This issue is my researchs subject. My goal with this paper was to understand why some children treated in HECC during the period between 1999 and 2007 were not registered. Seeking for an ethnographic approach, my objective was to find out the reasons for that fact. In order to do that, I have investigated the meanings of birth certificates with mothers and fathers, and their implication on interactions with educational institutions. Since some children were not registered because their mothers were not registered neither, I have incorporated the adults with no birth certificate in the investigation process. This issue suggests me an intriguing question for the debate about civil register which involves a social reproduction of society poor sectors. With this paper, I intend to contribute for the understanding of childhood background and Brazilian`s poor families, expecting that this investigation is an alert for the sectors which are responsible for the civil register system in Brazil. In addition, I intend to contribute for the elaboration of educational public policies. As working tools, I used a questionnaire, open interviews, conversations with mothers and fathers, documents and institutional material from HECC. My central dialogue occurred with Roberto DaMatta (1997a; 1997; 2000), Ana Liési Thurler (2004); and Cynthia Sarti (1996;2004) e Cláudia Fonseca (2005; in edition).

Imagens da anatomia interna são essenciais para as práticas médicas. Estabelecer correlação entre elas, é um importante procedimento para diagnóstico e tratamento. Nessa dissertação, é proposta uma abordagem para correlacionar dados multidimensionais de mesma modalidade de aquisição baseando-se somente nas informações de intensidade de pixels e voxels. O trabalho foi dividido em duas fases de implementação. Na primeira, foi explorado o problema de similaridade entre imagens médicas usando a perspectiva de análise de qualidade de imagem. Isso levou ao desenvolvimento de uma técnica de dois passos que estabelece um equilíbrio entre a velocidade de processamento e precisão de duas abordagens conhecidas. Avaliou-se a qualidade e aplicabilidade do algoritmo e, na segunda fase, o método foi estendido para analisar similaridade e encontrar a localização de uma imagem arbitrária (2D) em um volume (3D). A solução minimiza o número virtualmente infinito de possíveis orientações transversais e usa otimizações para reduzir a carga de trabalho e entregar resultados precisos. Uma visualização tridimensional volumétrica funde o volume (3D) com a imagem (2D) estabelecendo uma correspondência entre os dados. Uma análise experimental demonstrou que, apesar da complexidade computacional do algoritmo, o uso de amostragem, tanto na imagem quanto no volume, permite alcançar um bom equilíbrio entre desempenho e precisão, mesmo quando realizada com conjuntos de dados de baixa intensidade de gradiente. / Images of the inner anatomy are essential for clinical practice. To establish a correlation between them is an important procedure for diagnosis and treatment. In this thesis, we propose an approach to correlate within-modality 2D and 3D data from ordinary acquisition protocols based solely on the pixel/voxel information. The work was divided into two development phases. First, we explored the similarity problem between medical images using the perspective of image quality assessment. It led to the development of a 2-step technique that settles the compromise between processing speed and precision of two known approaches. We evaluated the quality and applicability of the 2-step and, in the second phase, we extended the method to use similarity analysis to, given an arbitrary slice image (2D), find the location of this slice within the volume data (3D). The solution minimizes the virtually infinite number of possible cross section orientations and uses optimizations to reduce the computational workload and output accurate results. The matching is displayed in a volumetric three-dimensional visualization fusing the 3D with the 2D. An experimental analysis demonstrated that despite the computational complexity of the algorithm, the use of severe data sampling allows achieving a great compromise between performance and accuracy even when performed with low gradient intensity datasets.

Submitted by Tatiana Lima (tatianasl@ufba.br) on 2016-04-26T18:26:29Z No. of bitstreams: 1 Rebouças, Osório Sampaio Rocha.pdf: 6286886 bytes, checksum: 73a1601447c7470e1b8e40d63718d8d6 (MD5) / Approved for entry into archive by Tatiana Lima (tatianasl@ufba.br) on 2016-04-26T18:30:07Z (GMT) No. of bitstreams: 1 Rebouças, Osório Sampaio Rocha.pdf: 6286886 bytes, checksum: 73a1601447c7470e1b8e40d63718d8d6 (MD5) / Made available in DSpace on 2016-04-26T18:30:07Z (GMT). No. of bitstreams: 1 Rebouças, Osório Sampaio Rocha.pdf: 6286886 bytes, checksum: 73a1601447c7470e1b8e40d63718d8d6 (MD5) / A categoria empresarial conhecida como Microemprendedor iniciou com a sanção da Lei Geral da Micro e Pequena Empresa. Esta lei oportuniza ao pequeno empreendedor a obtenção de tratamento diferenciado no que diz respeito a tributos, benefícios e direitos até então nunca disponibilizados aos micro e pequenos negócios. Nesta categoria empresarial, o empreendedor tem direito aos benefícios do INSS, emissão de nota fiscal, acesso a crédito, vantagens na participação de licitações e contratos públicos, dentre outras possibilidades. Nesse sentido, para que ele desfrute e usufrua desses benefícios é necessário estar em dias com suas obrigações. Para que o Microempreendedor Individual obtenha esses benefícios é preciso ter foco na criação de uma gestão eficiente e eficaz para que os resultados sejam satisfatórios. Com o objetivo de analisar os desafios da formalização enfrentados pelos Microempreendedores, foi realizada uma pesquisa de campo com um grupo de empresárias do setor de serviços (Cabeleireiras) enquadradas como Microempreendedoras. O intuito principal da pesquisa é compreender o cenário mundial, nacional e local onde estão inseridos estes empreendimentos, suas práticas diárias, suas táticas operacionais e as estratégias de gestão utilizadas em seus negócios para posteriormente sugerir uma Tecnologia de Gestão Social (TGS) capaz de contribuir com a redução da inadimplência e consequentemente proporcionar uma gestão “madura” condizente com as necessidades do negócio e do mercado. A avaliação desses fatores foi realizadas através dos resultados das entrevistas com essas empresárias e também por meio de visitas a órgãos como INSS, Receita Federal, Secretaria da Micro e Pequena Empresa e SEBRAE/NA realizadas no DF durante a Residência Social. Com os resultados dessa pesquisa foi possível entender, compreender e sugerir mudanças que contribuam para obtenção de resultados econômicos e sociais benéficos não só ao empresário, mas também a sociedade como um todo. The business category known as Microemprendedor was initiated with the sanction of the General Law of Micro and Small Enterprise. This law gives opportunity to small entrepreneurs to obtain differential treatment with regard to taxes, benefits and rights hitherto available to micro and small businesses. In this business category, the entrepreneur is entitled to benefits from social security, issue invoices, access to credit, benefits of participation in tenders and procurement, among other possibilities. However, to enjoy it and enjoy these benefits you must be on days with their obligations. For the Individual Microentrepreneur get these benefits you need to be focused on creating an efficient and effective management so that the results are satisfactory. In order to analyze the challenges faced by the formalization Micro-entrepreneurs was conducted field research with a group of entrepreneurs in the service sector (Hairdressers) classified in this business category. The main research goal is to understand the world stage, national and local where they live these developments, their daily practices, its operating tactics and management strategies used in their business to later suggest a TGS able to contribute to the reduction of default and consequently for a management "mature" consistent with business and market needs. The evaluation of these factors were performed using the results of interviews with these entrepreneurs and also through visits to organizations such as Social Security, IRS, Department of Micro and Small Enterprise and SEBRAE / NA held in Mexico City during the Social Housing. With the results of this research it was possible to understand, comprehend and suggest changes that contribute to achieving economic and social outcomes beneficial not only to the entrepreneur, but also for society as a whole.

Världens kuster och stränder har en viktig roll i samhället, både för ekonomin, gröna områden för rekreation och naturliga aspekter. Viktiga aspekter som även kan medför negativa konsekvenser för världens stränder. I Sverige skyddas stränderna genom strandskyddslagstiftning, som har till syfte att trygga allmänna och enskilda intressen samt trygga goda förhållanden för djur- och växtlivet. Strandskyddslagstiftningen är en from av naturvårdföreskrifter som alltid ska beaktas vid fastighetsbildning. Strandskyddet är generellt vilket medför att alla stränder och vattendrag i Sverige berörs. Strandskyddet utgår från strandlinjen och 100 meter upp på land och 100 meter ut i vattnet. Vid fastighetsbildning tillämpar Lantmätare den berörd lagstiftning samt samråd med berörda myndigheter för att inte motverka strandskyddets syfte. Examensarbetets syfte är att analysera tillämpningen av strandskyddet i fastighetsbildning, utifrån lässtyrelens och Lantmäteriets beslut. Målet är att finna skillnaden mellan hur länsstyrelsen och Lantmäteriet tillämpar strandskyddslagstiftningen i fastighetsbildning. Metoden till studien består av en kvalitativ analys, en juridisk analys och en litteraturstudie. Studiens utgångspunkt låg i att granska strandskyddslagstiftningen utifrån lantmäteriförrättningar och länsstyrelsens yrkanden till överklagandena. Vilket genomfördes av den juridiska analysen samt delar av litteraturstudien. Den kvalitativa studien bestod av ett frågeformulär som skickades till alla medverkande länsstyrelser i Sverige samt intervjuer med lantmätare. Studien skulle ha genomförts i hela Sverige men genomfördes enbart i Hälsingland. Resultatet av studien visade att skillnader finns i tillämpningen av strandskyddslagslagstiftningen i Hälsingland. Skillnaden kan bero på att strandskyddslagstiftningen är svårtolkad och ger utrymme för olika tillämpningar vid olika fastighetsbildningsåtgärder. / The coasts and shoreline of the world have an important role in society, both for the economy, green areas for recreation and natural aspects. Important aspects that can also adversely affect the world's shoreline. In Sweden, the shoreline is protected by shore protection laws, which aims to protect public and private interests and ensure good conditions for animal and plant life. Shore protection laws is a form of conservation regulations that must always be taken into account when registration of property. The shore protection is generally, which means that all shore and waters in Sweden are affected. The shore protection starts from the shoreline and 100 meters up to land and 100 meters into the water. When registration of property, the surveyors apply the applicable legislation and consult with the relevant authorities in order not to counteract the purpose of shore protection. The purpose of the thesis is to analyze the application of the shore protection laws in registration of property, on the decision of the country administrative board and the Swedish Mapping, Cadastral and Land Registration Authority, Lantmäteriet. The goal is to find the difference between how the county administrative board and the Lantmäteriet applies the shore protection in registration of property. The method of the study is based on a qualitative analysis, a legal analysis and a literature study. The purpose of the study was to review the shore protection laws regulations from Lantmäteriet and the county administrative board's claims to the appeals, which was carried out by the legal analysis and parts of the literature study. The qualitative study consisted of a questionnaire sent to all participating county administrative boards in Sweden and interviews with surveyors. The study would have been carried out throughout Sweden but implemented only in Hälsingland. The result of the study showed that there are differences in the application of the shore protection laws regulations in Hälsingland. The difference may be due to the fact that the shore protection of the is difficult to interpret, which allows for different applications for different registration of property.

In this thesis report, an approach to use Microsoft Kinect to scan an object and providea 3D model for further processing has been proposed. The additional requiredhardware to rotate the object and fully expose it to the sensor, the drivers and SDKsused and the implemented software are discussed. It is explained how the acquireddata is stored and an efficient storage and mapping method requiring no specialhardware and memory is introduced. The solution proposed circumvents the PointCloud registration task based on the fact that the transformation from one frame tothe next is known with extremely high precision. Next, a method to merge theacquired 3D data from all over the object into a single noise-free model is proposedusing Spherical Transformation and a few experiments and their results aredemonstrated and discussed.

Thesis (MTech (Quality))--Cape Peninsula University of Technology, 2008. / When prospective students decide to register at a university, their first encounter with university life will be the Registration Department. Should the process be inefficient without much regard for the personal wellbeing of the prospective student, it will leave a lasting impression on the student, and more often than not serve as an indication of the manner in which he or she would be treated in the future at the university. With the need for the Cape Peninsula University of Technology to attract top grade students, the institution needs to improve their registration process. This study attempts to measure students and staff attitudes and perception of the registration process, explore the different processes involved during registration and application, and investigate the different technologies available to improve these processes. This research attempts furthermore to determine what processes could be put into place to assure that Academics and the Administration Department works together to achieve a mutually beneficial database that could be used to the benefit of the students and the institution alike. This database should be accessed from any computer on the different campuses and be user friendly, to maximise the efficiency and throughput.

In this diploma thesis I have characterized the Registration into Real Estate Cadastre, which government agents has a competence about Real Estate Cadastre and own proceeding of registration. Shortly I have characterized register of real estate in Germany, as another member state of European Union.

The services for handicapped people and their transformation after 2007 The present graduation thesis deals with screening the situation in the area of social services for persons with different handicap, especially regarding the transformation of social services after 2007. In the theoretical part, I am describing particularly the characteristics of the previous and the current systems of social services. When characterising the previous system of social services, I concentrate on the legislation, governing this system. Further I am presenting the characteristics and status of the consulting services, and socially activating service, as in the further chapters I am dealing with the latter when presenting the services of the KONÍČEK, o. s. association. When presenting the new system of social services, I am describing in particular the basic principles of this system, changes it brings to the users, legislation and quality standards of the social services. A big chapter is devoted to the Social Services Act. Further chapters describe the financing of social services, education of workers in social services, and work of volunteers in social services. The practical part presents my hypothesis and the aims of the present work. Further chapters present the target group and describe the data collection. Data was collected in the form a guided interview, the questions were answered by the representatives of the given non-profit organization. This chapter includes also a presentation of the activities of the KONÍČEK, o. s. association before 2007, when the services were not registered. Further I am presenting the activities of the association in 2008, when the association was already a registered provider of social services. I am presenting, in the Discussion chapter, the screening of the transformation of social services after 2007, the obtained data, and I am offering their comparison with the outputs found out in the KONÍČEK, o. s. association, or with literature data.

Imagens da anatomia interna são essenciais para as práticas médicas. Estabelecer correlação entre elas, é um importante procedimento para diagnóstico e tratamento. Nessa dissertação, é proposta uma abordagem para correlacionar dados multidimensionais de mesma modalidade de aquisição baseando-se somente nas informações de intensidade de pixels e voxels. O trabalho foi dividido em duas fases de implementação. Na primeira, foi explorado o problema de similaridade entre imagens médicas usando a perspectiva de análise de qualidade de imagem. Isso levou ao desenvolvimento de uma técnica de dois passos que estabelece um equilíbrio entre a velocidade de processamento e precisão de duas abordagens conhecidas. Avaliou-se a qualidade e aplicabilidade do algoritmo e, na segunda fase, o método foi estendido para analisar similaridade e encontrar a localização de uma imagem arbitrária (2D) em um volume (3D). A solução minimiza o número virtualmente infinito de possíveis orientações transversais e usa otimizações para reduzir a carga de trabalho e entregar resultados precisos. Uma visualização tridimensional volumétrica funde o volume (3D) com a imagem (2D) estabelecendo uma correspondência entre os dados. Uma análise experimental demonstrou que, apesar da complexidade computacional do algoritmo, o uso de amostragem, tanto na imagem quanto no volume, permite alcançar um bom equilíbrio entre desempenho e precisão, mesmo quando realizada com conjuntos de dados de baixa intensidade de gradiente. / Images of the inner anatomy are essential for clinical practice. To establish a correlation between them is an important procedure for diagnosis and treatment. In this thesis, we propose an approach to correlate within-modality 2D and 3D data from ordinary acquisition protocols based solely on the pixel/voxel information. The work was divided into two development phases. First, we explored the similarity problem between medical images using the perspective of image quality assessment. It led to the development of a 2-step technique that settles the compromise between processing speed and precision of two known approaches. We evaluated the quality and applicability of the 2-step and, in the second phase, we extended the method to use similarity analysis to, given an arbitrary slice image (2D), find the location of this slice within the volume data (3D). The solution minimizes the virtually infinite number of possible cross section orientations and uses optimizations to reduce the computational workload and output accurate results. The matching is displayed in a volumetric three-dimensional visualization fusing the 3D with the 2D. An experimental analysis demonstrated that despite the computational complexity of the algorithm, the use of severe data sampling allows achieving a great compromise between performance and accuracy even when performed with low gradient intensity datasets.