Motivation A close association exists between hypertension and arterial stiffness. Whether the increased arterial stiffness seen in hypertensives are due to structural or functional adaptations in the vasculature is uncertain. Hypertension is more common in blacks and they have an increased arterial stiffness and higer stroke prevalence than white populations. Arterial stiffening, or a loss of arterial distensibility, increases the risk for cardiovascular events, including stroke and heart failure, as it increases the afterload on the heart, as well as creating a higher pulsatile load on the microcirculation. The stiffness of the carotid artery is associated with cardiovascular events, like stroke, and all-cause mortality. Furthermore, carotid stiffness is independently associated with stroke, probably because stiffening of the carotid artery may lead to a higher pressure load on the brain. Inflammation, endothelial activation, dyslipidemia, hyperglycemia and health behaviours may also influence hypertension and arterial stiffness. Limited information is availiable on these associations in black South Africans. The high prevalence of hypertension and cardiovascular disease in blacks creates the need for effective prevention and intervention programs in South Africa. Aim We aimed to compare the characteristics of the carotid artery between 5-year sustained hypertensive and normotensive black participants. Furthermore, we aimed to determine whether blood pressure, conventional cardio-metabolic risk factors, markers of inflammation, endothelial activation and measures of health behaviours are related to these carotid characteristics. Methodology This sub-study forms part of the South African leg of the multi-national Prospective Urban and Rural Epidemiology (PURE) study. The participants of the PURE-SA study were from the North West Province of South Africa, and baseline data collection took place in 2005 (N=2010), while follow-up data was collected five years later, in 2010 (N=1288). HIV-free participants who were either hypertensive or normotensive (N=592) for the 5-year period, and who had complete datasets, were included in this sub-study. The study population thus consists of a group of 5-year sustained normotensive (n=241) and hypertensive (n=351) black participants. Anthropometric measurements included height, weight, waist circumference and the calculation of body mass index (BMI). We included several cardiovascular measurements, namely brachial systolic- and diastolic blood pressure, heart rate, central systolic blood pressure, central pulse pressure and the carotid dorsalis-pedis pulse wave velocity. Carotid characteristics included distensibility, intima media thickness, cross sectional wall area, maximum and minimum lumen diameter. Biochemical variables that were determined included HIV status, low-density lipoprotein-cholesterol, high-density lipoprotein-cholesterol, triglycerides, fasting glucose, glycated haemoglobin (HbA1c), creatinine clearance, interleukin-6, C-reactive protein, intracellular adhesion-molecule-1 and vascular adhesion molecule-1. Health behaviours were quantified by measuring γ-glutamyltransferase and by self-reported alcohol, tobacco and anti-hypertensive, anti-inflammatory and lipid-lowering medication use. We compared the normotensive and hypertensive groups by using independent t-tests and chi-square tests. The carotid characteristics were plotted according to quartiles of central systolic blood pressure by making use of standard analyses of variance (ANOVA) and the analyses of co-variance (ANCOVA). Pearson correlations done in the normotensive and hypertensive Africans helped to determine covariates for the multiple regression models. We used forward stepwise multiple regression analyses with the carotid characteristics as dependent variables to determine independent associations between variables. Results and Conclusion The cardiovascular measures, including pulse wave velocity, were significantly higher in the hypertensive group (all p≤0.024). The lipid profile, markers of inflammation, endothelial activation and glycaemia, as well as health behaviours, did not differ between the hypertensives and normotensives after adjustments for age, sex, waist circumference, γ-glutamyltransferase, tobacco use and anti-hypertensive medication use. After similar adjustments, all carotid characteristics, except IMT, were significantly different between the groups (all p≤0.008). However, upon additional adjustment for cSBP, significance was lost. The stiffness and functional adaptation seen in this study are not explained by the classic cardio-metabolic risk factors, markers of endothelial activation or health behaviours of the participants. The differences that exist in terms of arterial stiffness between the normotensive and hypertensive groups may be explained by the increased distending pressure in the hypertensive group. Despite their hypertensive status, it seems that there are no structural adaptations in these hypertensive Africans. / MSc (Physiology), North-West University, Potchefstroom Campus, 2015

Motivation: The different coping styles used to respond to psychosocial stress have been linked to the development of cardiovascular disease (CVD). However, the manner in which the cardiovascular system is influenced differs between the coping styles. Of the different coping styles, defensive active coping (AC) has been shown to be the most detrimental to cardiovascular health. This is worsened by augmented α-adrenergic cardiac responses found in Africans. Furthermore, many studies have found that the prevalence of hypertension and other CVDs is much higher in urban Africans when compared to their Caucasian counterparts. This can be attributed to certain lifestyle changes implemented by Africans in the transition that occurs with urbanization, where they are forced to cope with an urban-dwelling lifestyle. One of these lifestyle factors, which also poses as a cardiovascular risk factor, is increased usage and in some cases abuse of alcohol. Certain discrepancies exist between ethnicities with regard to the metabolism of alcohol, which influences the effect of alcohol on the individual. Alcohol usage as a possible manner of coping has been supported in many instances, but the interdependent effects of alcohol usage and AC as cardiovascular risk factors has only been found in African men. Further investigation is needed to determine if coping and alcohol abuse act in tandem only in African men, or also in other ethnic or sex groups. What also needs to be discussed is whether the inconsistencies between ethnicities regarding alcohol metabolism, plays a part in the development of CVD in a bi-ethnic gender cohort. Objectives: The main aims of this study were to determine 1) receiver operated characteristic (ROC) ethnic specific cut points of alcohol usage in the prediction of ambulatory hypertension, and 2) to assess if these cut points in defensive active groups revealed increased cardiometabolic risk in a bi-ethnic sex cohort, and if so, whether the increased risk will be associated with a specific race or sex group? Methodology: This sub-study forms part of the SABPA (Sympathetic activity and Ambulatory Blood Pressure in Africans) study, conducted from 2008 to 2009. After exclusion criteria were applied, our bi-ethnic sex cohort consisted of 390 individuals. These participants were all from the Kenneth Kaunda Education District of the North-West province in South Africa, and they all signed informed consent prior to participation. The SABPA study was approved by the Ethics Review Board of the North-West University, with additional ethical approval for this sub-study. All procedures in this study complied with the guidelines of the Declaration of Helsinki. Each participant completed a psychosocial battery supervised by registered clinical psychologists, and information regarding their medication use and medical history was obtained. They also completed the Coping Style Indicator questionnaire which was developed by Amirkhan, to identify the coping style habitually used. Ambulatory blood pressure and ECG measurements were recorded for a 24h period with the Cardiotens CE120®. Anthropometric measurements were performed by ISAK (International Society for the Advancement of Kinanthropometry) level 2 accredited anthropometrists using calibrated instruments. Out of this, the body surface area were calculated. The physical activity of each participant was determined by use of the Actical® omnidirectional accelerometer. Resting blood samples were collected by a registered nurse. The following blood serum levels were determined: gamma-glutamyl transferase (γ-GT) as a marker for alcohol usage, C-reactive protein, cholesterol, high density lipoprotein, triglycerides, cotinine, reactive oxygen species and glycated haemoglobin levels. All statistical analyses were done using Statistica version 12.0. Descriptive statistics were conducted to state the baseline characteristics of the entire group, while Chi-square (X2) tests were used to determine prevalence for medications and pathology. ROC analyses were computed to establish a cut point for γ-GT predicting ambulatory hypertension in each ethnicity as well as in the entire group. Independent t-tests identified confounders, after which two-way analysis of covariance (ANCOVA) tests were computed to test a 2 x 2 main effects interaction (race x γ-GT cut points) for all cardiometabolic risk markers and to compare the different ethnic groups. ANCOVAs were then performed in the ethnic groups with high γ-GT as well as in above mean AC for the graphs that followed. Lastly, odds ratios (OR‟s) with 95% confidence intervals (CI‟s) were calculated in several models to highlight the odds of high alcohol intake to predict ambulatory hypertension in the ethnic-sex groups as well as in AC ethnic-sex groups. Significant values were noted as p ≤ 0.05. Results: The Africans revealed higher cardiometabolic risk markers, above mean defensive active coping, seeking social support with less avoidance coping scores. ROC analyses revealed that ambulatory hypertension commences at a much higher level of γ-GT in the Africans [55.7U/l (AUC=0.69; 95% CI: 0.61; 0.76)] with sensitivity /specificity of 47%/83% compared to the Caucasians [19.5U/l (AUC=0.747; 95% CI: 0.68; 0.82)] with sensitivity/specificity of 70%/73%. The Caucasians thus reveal an increased sensitivity for alcohol ingestion at a much lower γ-GT cut point compared to the Africans. When comparing ethnic specific ROC cut point groups, we found that certain levels of cardiometabolic risk factors such as C-reactive protein, systolic blood pressure, waist circumference and silent ischemic events, were significantly higher in the African group, especially in above mean AC groups. Out of the Africans with high γ-GT levels, 73% used the AC style, suggesting hypervigilant AC coping and increased CVD risk in Africans. Clinical significance was determined by OR‟s, which demonstrated that high γ-GT levels in AC African men predicted ambulatory hypertension with an OR of 7.37 (95% CI: 6.71 – 8.05). Higher alcohol intake predicted ambulatory hypertension in AC Caucasians with an OR of 2.77 (95% CI: 2.31 – 3.23) in men and 6.42 (95% CI: 5.85 – 7.0) in women respectively. Conclusion: γ-GT cut-points in defensive active groups revealed increased cardiometabolic risk markers in a bi-ethnic sex cohort. A possible hypermetabolic state in African men may initially protect them against CVD morbidity but if chronically challenged with no forthcoming social support, CVD risk is imminent. / MSc (Physiology), North-West University, Potchefstroom Campus, 2015

This Bachelor thesis is an interpretive study, where the material has mainly been gathered through ethnographic methods, with thematically opened interviews and observations providing the primary data. A field study was conducted in Bolivia during the months of November and December of 2009; in La Paz in the Western highlands, including some interviews in the fast growing suburb El Alto, as well as in Santa Cruz de la Sierra in the Eastern lowlands. Bolivia is one of the poorest and most unequal countries in Latin America and the world, and the purpose of the study is to re-contextualise and re-interpret how inequality is created and maintained in the Bolivian society by doing a case study on gender inequality. In addition, an intersectional analysis is used that takes into account the diversity of the Bolivian society in terms of ethnicity and class. The study aims at exploring the mechanisms that create and maintain inequality in a Bolivian context as well as looking at the prospects for potential change in the unequal relations between groups of people within the new context of indigenous president Evo Morales and a new inclusive constitution. Using an abductive method, the empirical material has been re-interpreted with the help of American sociologist Charles Tilly’s framework of durable inequality. He identifies two mechanisms that create inequality, exploitation and opportunity hoarding, and two mechanisms that reinforce inequality; emulation and adaptation. Together with the concept of intersectionality, recognising women’s different experiences depending on, for instance, ethnic background or social class, these two frameworks are framing the study. Jointly they generate a new analytical tool that can deepen the understanding inequality mechanisms: the Intersecting Inequality Framework. The content of the interviews when analysed show that inequalities in Bolivia have long historical roots, and that the processes of exploitation, opportunity hoarding, emulation and adaptation that Tilly describes all take place in creating and maintaining an unequal position for Bolivian women. The Intersecting Inequality Framework reveals that the inequality mechanisms in the three dimensions of gender, ethnicity and class sometimes work autonomously and other times intersectionally. Changing durable inequality is a slow process; nevertheless there are signs of changed relations between categorical bounded groups in the Bolivian society. Although, in the context of Morales the main political focus at the time lays not on attaining gender equality, but rather to continue the empowerment of the indigenous populations.

The purpose of this thesis is to investigate Sweden’s ability to adopt positive actions based on gender and ethnicity into national legislation, in regard to EU regulations. The possibility to use positive actions is established at an EU level by both treaties and directives. EU-case law narrows the practical use of the measure. Sweden has chosen to implement positive action based on gender but not ethnicity in their national legislation, despite the fact that the allowed extent to use it would have been the same. The purpose is further to gain a deeper understanding of the problems, as well as the beneficiary effects, that positive actions based on ethnicity could lead to. The thesis applies a combination of both legal method and sociology of law perspectives. Intersectional perspectives have been applied in the thesis to obtain further knowledge about the structural discrimination of ethnic minorities in Sweden. The thesis includes an investigation of the legal grounds of positive actions based on gender to enable comparisons but the main focus will be on positive actions based on ethnicity. The Swedish discussion on positive action based on ethnicity is mainly focusing on the problem of compiling statistics on people’s ethnicity, which may be a necessary consequence of the measure to achieve explicitness. The most obvious benefit with positive action based on ethnicity is that it aims to improve the situation on the labor market of disadvantaged groups. People with foreign ethnical backgrounds are systematically discriminated in the Swedish society and since Sweden currently is facing a great migratory movement, the need for measures against systematic discrimination grows. Dividing the population into different categories can lead to segregation rather than integration on the labor market. The problem arises when the will to create opportunities for foreigners contradicts the Swedish fear of categorizing people. Possible solutions with perhaps more long-term outcomes could be to increase employers awareness of the positive economic effects of diversity in the workforce and also to increase awareness among the Swedish population about the systematic discrimination of foreigners to change social norms.

The concept of identity and identities have a long history, especially regarding societal and behaviour studies. Many of them are analyzed trough class-schemes or family-situations, others are based on more direct approaches, such as income and education. This paper are examining a fraction of these different theories, and then applying it to the main purpose of the study, which is to examine different kinds of identities in context to subjective social status. Furthermore will the analysis concern different kinds of capital, which also will be presented in context to identities and subjective social status. This kind of analysis where possible by using already existing quantitative data from ISSP (International social survey programme) and their 2003 draft about National identity. My debentent variable, self-concept (subjective social status), was extracted through the existing material. The study was concentrated to the Scandinavian countries of Sweden, Denmark, Norway and Finland.        By presenting these results through frequency and mean-tables, and multiple-regressions, but also with the theoretical framework, then it stands clear that their is no direct relation between identities and subjective social status, expect for religious identification. It is presented as that the capital itself are more influencial.

National prevalence surveys indicate that lifetime and recreational drug use among all social classes have increased steadily over the last decade in Ireland (Moran et al., 2001a, Mayock, 2002, National Advisory Committee on Drugs, 2008a). Drugs research has been traditionally based on the identification, weighting and interrelatedness of risk and protective factors within a "risk prevention paradigm". This paradigm has been criticised for its lack of inclusion of individual, group and wider structural aspects, and occurs within a greater awareness of greater social discourse and societal shifts. The research papers in this portfolio of work are thematically analysed and conceptualised within the theoretical framework of cognitive and structural social capital. The descriptive research and later, more conceptual papers investigating drug use among rural youth, Travellers and cocaine use, are thereby explored in terms of the potential ‘normalisation of rural youth drug use’ within contemporary risk discourse, the assimilatory threat of increasing drug use among the ‘Traveller community’., and the emergence of the ‘recreational cocaine user’ in Irish society. The social processes of individualisation, reciprocity and trust which constitute social capital are deemed to provide potent collective frameworks for the navigation of risk in day to day ‘localised’ settings. The ‘interrelated normative frameworks’ and ‘processes of risk neutralisation’ are underpinned within a wider social capital understanding of the meaning of drug activity in associational life based on ‘interpersonal and institutional trust’ and ‘mutual resource acquisition’. Contemporary drug policies must consider the contextual constraints of the ‘risk society’, which impact on inherent individual ‘power resources’, whereby individual agency and drug taking is better understood within situational agency of ‘localised’ social, gender, ethnic and cultural capital.

Research has long established that racial/ethnic minority residential segregation is related to a variety of social problems, including poor health and health care outcomes. Yet, little research in this area has attempted to tease out the mechanisms underlying this association. Furthermore, within this work, few studies address this relationship for racial/ethnic minority groups outside of the Black/White differences. In this dissertation, I argue that community organizations and service providers in neighborhoods provide important local sites which can improve residents' access to key health-related resources. I put this forward as a mechanism which can link segregation to health and health care outcomes, in that racial/ethnic minority neighborhoods are less likely to have a variety of such establishments compared to their White counterparts. I test this mechanism through a series of three empirical studies. In the first, using a nation-wide health data set combined with metropolitan area measures, I examine the association between racial residential segregation and poor self-rated health. I include the three largest racial/ethnic minority groups in the U.S. - Blacks, Latinos, and Asians. I find that the segregation of each group is related to a greater likelihood of poor self-rated health. However, for Black respondents, this is partially accounted for by economic variables at the metropolitan level, and for Asian respondents, is fully accounted for by recent immigration. In the second study, I analyze the distribution of health-related facilities by segregation status using a nation-wide Census data source. I find that racial residential segregation for Blacks, and to a lesser extent Latinos and Asians, is related to a decrease in the density of such facilities, including food sources, fitness facilities, pharmacies, a number of health care organizations, civic society, and social services. The inclusion of socio-economic indicators removes this effect for most of the health care organization outcomes, across all three groups. In the third and final study, I examine this full pathway using the case of the Phoenix urbanized area. Using a 2013-2014 survey of families about their children's health care utilization combined with area-level Census measures, I test where families are able to obtain care for their children, if any location, in light of what is physically proximate to them in space, and how this may be patterned or constrained by the segregation status of their local neighborhood. I find that Latino and Native American segregation is related to a decreased number of health care facilities. Further, the lack of such facilities is related to a decreased likelihood of families being able to utilize a physician's office as their regular source of care, versus a clinic or health care center. However, for those who do not have a regular source of care, or who utilize an emergency room, this seems to be patterned more by economic considerations, chiefly whether or not the child has health insurance. Further, the distribution of health care organizations also accounts for a sizable portion of the effect of segregation on health care utilization choices. As a whole, this dissertation demonstrates that segregation, for a number of racial/ethnic minority groups, is related to a lower density of a number of health-related organizations, both in a nationwide analysis, as well as through an extended case study of the Phoenix area. Moreover, using the Phoenix case, I find that the lack of such facilities is consequential, and that at least for certain health care providers, patterns where families are able to go for their children's health care needs. This suggests that the distribution of health-related organizations and service providers across communities may serve as an important explanatory mechanism to understand the association between segregation and a variety of health and health care outcomes.

This intersectional study explores how the social constructed categories gender and ethnicity interact with each other in photos picturing Swedish athletes. The studies empirical material is collected from the sport section of the biggest Swedish tabloid newspaper Aftonbladet, and was published during the period 23rd of November, 2012 to 23rd of November, 2015. The photos has been analyzed with a semiotic analysis which establishes that there are discriminating differences in how the athletes are being portraited. The most comprehensive differences are found between the groups ethnical Swedish men and ethnical non-Swedish women.

The main purpose of this quantitative and qualitative study A study in crime: about sexuality, ethnicity and mental illness has been to reveal the relation between how the evening newspaper Aftonbladet and the Internet forum Flashback forum represent two men who has been convicted for the murder of two underaged girls. Hence more than one sixth of the swedish population has a lot of confidence in this newspaper it has been important to see how mental illness, sexuality, masculinity and ethnicity is produced and therefore reproduced through its descriptions of these men. The central theories which have been used to visualize the representation of masculinity, sexuality, ethnicity and mental illness is R.W. Conell´s theory of hegemonic masculinity, Judith Butler´s hetereosexual matrix, semiotics, media commodification and framing. In addition, previous studies in the media reporting of the convicted rapist ”Hagamannen” and the terrorist Anders Behring Breivik as well as theory of the ideal vicitim and therefore the ideal perpretator has been relevant. The material consists of a number of articles about the resolution of the homicide of Lisa Holm in 2015 and Helén Nilsson in 2004 in which Nerijus Bilevicus and Ulf Olsson were condemned. Furthermore, comments on Flashback forum where the abovementioned cases have been discussed were analyzed. Denotation and connotation, the heterosexual matrix and the pressethical rules applied as methodological tools. In the current media landscape of 2016 newpapers´ foremost competitors of the readers’ attention are the complimentary websites and Internet forums. The comparison indicated that the users of Flashback forum discussed similar subjects as Aftonbladet regarding the previous mentioned attributes. Also, we identified that the journal more frequentely violated the pressethical rules in the describtions of the perpetrator who suffered from mental illness and was both bisexual, transsexual and also a pedofile. However, the ethnicity of the second perpetrator appeared early in the reporting of the homicide. The results of the study have shown that the mechanisms of the commodification of media were more substantial in 2004/2005, concerning the descriptions of the perpetrator. The journal in 2015/2016 does not seem to have delievered such information to satisfy the crowd in comparison to the comments on Flashback forum. This is in contrary to the admitted opinion by media scholars.

Anti-racist legislation and education reforms for the past two decades in Brazil have required that curriculum in all basic education combat prejudice and racism and promote critical thinking of the nation's past and current ethnic-racial relations in an effort to construct a society that is more democratic, equal, and just. In response to the reforms, textbooks have been rewritten. This study analyzes one high school history textbook series that was approved by Brazil in 2012, and asks: How, and to what extent, do these new high school history textbooks address critical reflection on race and racism in Brazil? Using qualitative content analysis, I coded the above series for its attention in these matters. My findings reflect that though there are a number of cases where racism in Brazil was admitted, more explanation on the content on racism is needed, the content was too vague, or it lacked necessary details to make its analysis more informed for student reflection.