In an effort to develop an optical-acoustical understanding of ultrasound contrast agent microbubble dynamics in a micro-environment that resembles blood vessels, this thesis presents experimental work on optical trapping and acoustical probing of ultrasound contrast agent microbubbles confined in regenerated cellulose capillaries. First, we showed by acoustical means that the pressure threshold of an individual microbubble shell rupture increases significantly when confined in regenerated cellulose capillaries. We report that the shell rupture threshold in regenerated cellulose capillaries increased by at least 0.3 MPa from 0.8 MPa for unconfined microbubbles. Second, we achieved optical trapping and manipulation of ultrasound contrast agent microbubbles confined in capillaries using Hermite-Gaussian laser beams. / Graduation date: 2012

A study of the effect of catalyst properties on the synthesis of carbon nanotubes (CNTs) is done in this thesis. Three different metal alloy catalysts, Fe/Ti, Ni/Ti, Co/Ti, have been studied. Various atomic concentrations and thicknesses were cosputter deposited on clean Si wafers using AJA Orion 4 RF Magnetron sputter deposition tool at 5mtorr and 17��C, and the films were characterized using a scanning electron microscope, Energy-dispersive X-ray spectroscopy. All the alloys have been annealed at 650��C and 3 torr in an argon atmosphere at 100 SCCM, followed by ammonia gas plasma etch at different powers at 3 torr and 50 SCCM NH��� flow in a modified parallel plate RF chemical vapor deposition tool for 1 minute. The influence of plasma power, thickness of catalyst and concentration of Ti the secondary metal in the alloy composition, on the surface morphology of the catalyst are investigated by characterizing them with atomic force microscopy. The study has shown that the surface roughness is affected by Ti concentration, thickness and plasma power. The 35 W power NH��� plasma produced rougher surfaces when compared to the 75 W NH��� plasma. The result is interpreted as follows: ion bombardment leads to greater etching of the catalyst surface. Thus, plasma power must be optimized for catalyst thin film and etch time. The study has provided an in depth analysis and understanding of the various factors that influence catalyst surface morphology which can be applied into further study for optimizing parameters for synthesis of single walled CNTs. Following this, a study on catalysts for CNT synthesis was performed using Plasma enhanced chemical vapor deposition and characterized by scanning electron microscope. CNTs were synthesized on Ni, Ni-Ti, Co, Co-Ti and Fe catalyst. Ni, Ni-Ti catalyst produced forest like vertically aligned CNTs whereas Co, Co-Ti produced vertically aligned free standing CNTs. The growth was dense and uniform across the substrate. Initial growth runs on Fe, Fe-Ti alloy did not produce any CNTs until catalyst was restructured with a thicker Ti under layer after an investigation using Secondary ion mass spectrometry of suspected Fe catalyst poisoning due to reaction with Si substrate. A room temperature run was carried out on annealed and plasma etched Ni catalyst and no CNTs were produced indicating the importance of substrate temperature of CNTs. A deeper understanding of factors of influence on CNTs such as catalyst types, structure/morphology, and substrate temperature has been achieved with this study. / Graduation date: 2013

Thesis (Ed. S.)--Miami University, Dept. of Educational Psychology, 2007. / Title from first page of PDF document. Includes bibliographical references (p. 30-35).

Coalbeds are an extremely complicated porous medium with characteristics of heterogeneity, dual porosity and stress sensitivity. In the past decades great achievements have been made to the simulation models of pressure depletion coalbed methane (CBM) recovery process and CO2 sequestration and enhanced coalbed methane (ECBM) recovery process. However, some important mechanisms are still not or not properly included. Among them, the influence of geomechanics is probably the most important one. Because of its influence coalbed permeability, the key parameter for the success of recovery processes, changes drastically with alterations of in situ stresses and strains during these processes. In present reservoir simulators, the change of coalbed permeability is estimated with analytical models. Due to the assumptions and over simplifications analytical models have limitations or problems in application. In this research to properly estimate the changes of permeability and porosity in the simulation of CO2 sequestration and ECBM recovery process, comprehensive permeability and porosity models have been developed with minimum assumptions and simulation methods established. Firstly, a set of continuum medium porosity and permeability coupling models is built up and a simulation procedure to apply these models in reservoir and geomechanical coupled simulations proposed. Using the models and simulation procedure a sensitivity study, mainly on the parameters related to coalbed permeability change and deformation, has been made for the CBM recovery process. Then based on the understanding, a set of discontinuum medium porosity and permeability coupling models is developed and a procedure to apply these models in reservoir and geomechanical coupled simulations presented. The new models are more comprehensive and adaptable, and can accommodate a wide range of coalbeds and in situ conditions. The proposed equivalent continuum deformation model for coal mass is validated by simulating a set of lab tests including a uniaxial compression test in vacuum and a CO2 swelling test under axial constraint in the longitudinal (vertical) direction. At last the discontinuum medium porosity and permeability coupling models and the simulation procedure are successfully applied to simulate part of a series of micro-pilot tests of ECBM and CO2 sequestration at Fenn Big Valley of Alberta, Canada. / Geotechnical Eengineering

L’eau est vitale dans toutes les économies. C’est à cause de son rôle prépondérant pour la survie que les tensions politiques autour des basins et des fleuves internationaux tendent à être particulièrement très épineuses. Actuellement, la mauvaise répartition de cette ressource pose un sérieux problème du fait qu’elle est gérée en fonction de stratégies politiques et non en fonction des réalités hydrologiques régionales. Nous expliquons à l’aide de la « Enhanced Power Matrix Model » (La Matrice de FREY et NAFF améliorée) que les tensions autour des bassins et des fleuves au Moyen – Orient n’aboutiront pas à des conflits armés mais à une situation de non guerre et de non paix, très peu propice à la coopération. Pour sortir de cette situation de blocage, nous proposons aux décideurs politiques et aux négociateurs, sur base de l’article 6 de la Convention de New York de 1997 sur « les cours d’eau internationaux à d’autres usages que la navigation », un modèle de répartition de la ressource hydrique entre les différents riverains d’un cours d’eau international. Face à cette situation, beaucoup de pays de la région tentent de mettre de façon unilatérale des modèles de gestion macroéconomique : réduction de la demande ou l’augmentation de l’offre de l’eau. Ces modèles se heurtent à des obstacles de nature économique, politique, sociologique et culturelle. Dans un objectif de conception de nouveaux modèles de gestion de l’eau, nous proposons un modèle coopératif, les projets de transfert inter – bassin, pour faire face à la mauvaise répartition de cette ressource au Moyen – Orient. Nous appuyons sur la méthodologie multicritère d’aide à la décision pour opérationnaliser l’article 6 de la Convention de New York et pouvoir comparer les différents projets de transfert inter - bassin. Cette méthodologie fait appel à un logiciel d’aide à la décision « Décision Lab 2000 ». Le commentaire des résultats fournis par ce logiciel nous a permit de tirer l’enseignement suivant : seuls les projets qui présentent une faisabilité politique élevée arrivent en tête de classement. Ce qui nous fait dire que la question de l’eau au Moyen – Orient est, avant tout, une question politique.

Skattemyndigheter världen över arbetar med att hantera den skatteinbetalning som behövs för att finansiera och driva samhället. Fullständig skatt betalas inte in och de uteblivna skatteintäkterna utgör det så kallade skattefelet, vilket definieras som skillnaden mellan den teoretiskt korrekta skatten som borde betalats in och den faktiskt fastställda skatten. Alla skattemyndigheter arbetar med olika medel och i olika omfattning för att minska skattefelet. De utför delvis kontroller och granskningar samt informerar och uppmuntrar skattebetalarna till att göra rätt. Kontroller kan utföras dels genom olika typer av stickprov, eller genom att identifiera riskområden och primärt inrikta resurserna till dessa områden. Globaliseringen har medfört att företag ofta både opererar och handlar i ett flertal länder. Detta bidrar till en allt mer komplicerad skattemiljö vilken har gett upphov till ett behov av en förändring. Främst påverkas de stora företagen som också står för en betydande del av skatteintäkterna. Skattemyndigheter i vissa länder har med olika metoder börjat arbeta för en ökad relation tillsammans med de stora företagen. Genom att erhålla utökad information om företagen blir det lättare att identifiera risker för fel och kontrollera dessa. Företagen tjänar på att behovet för kostsamma revisioner minskar och att de erhåller en ökad säkerhet i sin skatteposition, då avklarade ärenden inte kommer att granskas i framtiden. Skatteverket i Sverige driver idag ett riksprojekt mot skatteplaneringsaktiva som bland annat syftar till att skapa en ökad effektivitet genom en förbättrad riskhantering. Det nya arbetssättet kan, enligt indikationer, komma att ha liknelser med en del utländska arbetssätt. I och med detta fann vi det aktuellt att utföra en komparativ fallstudie av ett urval av länder för att se hur de arbetar med riskhantering och hur det visat sig fungera. Vår undersökning visar att dessa typer av arbetssätt överlag har fått positiv respons av både företag och skattemyndigheter i samtliga av de undersökta länderna. Det har bland annat bidragit till en ökad effektivitet i granskningsprocesser, en förbättrad relation mellan parterna samt en ökad säkerhet hos företagen gällande deras skatteposition. Dock finner vi att det har visat sig svårt att frambringa ett ändrat beteende hos företagen gällande deras skatteplanering.

Technology evolution throughout history has initiated many changes in different aspects of human activities. Learning, as one of the most representative human activities has also been subject to these changes. Nowadays, the use of information and communication technologies has considerably changed the way people learn and collaborate. These changes have been accompanied by new approaches to support learning using a wide range of mobile devices, software applications and different communication platforms. In these technology rich landscapes, the notion of context emerges as a crucial component to be considered for the design and technical implementation of technology-enhanced learning environments. The main research question investigated in this thesis relates to the use of different context instantiations for the design and development of innovative technology-enhanced learning environments.This thesis is a collection of eight papers that describe the results of the research efforts conducted in four different experimental cases during a period of four years. These experiments have been designed and developed as part of two research projects. The theoretical foundations that guided this research were based on the view of context and interaction from a learning theory, human-computer-interaction perspective, as well as dimensional data modelling techniques. Different methodological approaches, (such as action-oriented, design-based research and case study) have been used while investigating the main research question. The main contribution that this thesis offers to the research community is a conceptual context model accompanied by a dimensional data model that can be used as a design tool for embedding learning activities in context. In the four trials that encompass my empirical work, the conceptual model proposed in the thesis guided the design and technical development of the different novel technology-enhanced learning activities. The outcomes of these efforts provided various insights regarding the use of different context instantiations that have implications for the design and development of these environments. This thesis advocates that computational context attributes should be used as metadata descriptors that would potentially promote personalization and interoperability of digital learning content. Content personalization offers opportunities for personalized learning that increases learners’ engagement and eventually could lead to better learning results. Furthermore, the research and industrial community could use the context model developed in this thesis as a guiding tool to promote the creation of new ways to personalize services and technologies.

The main theme of this thesis is to study effects of different environments on geometric and electronic structures, as well as optical responses, of molecules using time-(in)dependent density functional theory. Theoretical calculations have been carried out for properties that can be measured by conventional and advanced experimental techniques, including one-photon absorption (OPA), two-photon absorption (TPA), surface-enhanced Raman scattering (SERS) and second order nonlinear optical (NLO) response. The obtained good agreement between the theory and the experiment allows to further extract useful information about inter- and intra-molecular interactions that are not accessible experimentally. By comparing calculated one-photon absorption spectra of aluminum phthalocyanine chloride (AlPcCl) and AlPcCl -water complexes with the corresponding experiments, detailed information about the interaction between water molecules and AlPcCl, and geometric changes of AlPcCl molecule has been obtained. Effects of aggregation on two-photon absorption spectra of octupolar molecules have been examined. It is shown that the formation of clusters through inter-molecular hydrogen bonding can drastically change profiles of TPA spectra. It has also demonstrated that a well designed molecular aggregate/cluster, dendrimer, can enhance the second order nonlinear optical response of the molecules. In collaboration with experimentalists, a series of end-capped triply branched dendritic chromophores have been characterized, which can lead to large enhancement of the second order NLO property when the dipoles of the three branches in the dendrimers are highly parallelized. Surface-enhanced Raman scattering has made the detection of single molecules on metal surface become possible. Chemically bonded molecule-metal systems have been extensively studied. We have shown in a joint experimental and theoretical work that stable Raman spectra of a non-bonding molecule, perylene, physically adsorbed on Ag nano-particles can also be observed at low temperature. It is found that the local enhanced field has a tendency to drive molecule toward a gap of two closely lying nano-particles. The trapped molecule can thus provide a stable Raman spectrum with high resolution when its thermal motion is reduced at low temperature. For the ever growing size of molecular complexes, there is always the need to develop new computational methods. A conceptually simple but computationally efficient method, named as central insertion scheme (CIS), is proposed that allows to calculate electronic structure of quasi-periodic system containing more than 100,000 electrons at density functional theory levels. It enables to monitor the evolution of electronic structure with respect to the size of the system. / QC 20100823

Meltwater reaching the base of the snowpack may either infiltrate the underlying stratum, run off, or refreeze, forming a basal ice layer. Frozen ground underneath a melting snowpack constrains infiltration promoting runoff and refreezing. Compositional changes in chemistry take place for each of these flowpaths as a result of phase change, contact between meltwater and soil, and mixing between meltwater and soil water. Meltwater ion concentrations and infiltration rate into frozen soils both decline rapidly as snowmelt progresses. Their temporal association is highly non-linear and the covariance must be compensated for in order to use time-averaged values to calculate chemical infiltration over a melt event. This temporal covariance is termed �enhanced infiltration� and represents the additional ion load that infiltrates due to the timing of high meltwater ion concentration and infiltration rate. Both theoretical and experimental assessments of the impact of enhanced infiltration showed that it causes a greater ion load to infiltrate leading to relative dilute runoff water. Sensitivity analysis showed that the magnitude of enhanced infiltration is governed by initial snow water equivalent, average melt rate, and meltwater ion concentration factor. Based on alterations in water chemistry due to various effects, including enhanced infiltration, three major flowpaths could be distinguished: overland flow, organic interflow, and mineral interflow. Laboratory experiments were carried out in a temperature-controlled environment to identify compositional changes in water from these flowpaths. Samples of meltwater, runoff, and interflow were filtered and analyzed for major anions and cations. Chemical signatures for each flowpath were determined by normalizing runoff and interflow concentrations using meltwater concentrations. Results showed that changes in ion concentrations were most significant for H⁺, NO₃^�, NH₄⁺, Mg²⁺, and Ca²⁺. Repeated flushes of meltwater through each interflowpath caused a washout of ions. In the field, samples of soil water and ponding water were collected daily from a Rocky Mountain hillslope during snowmelt. Their normalized chemical compositions were compared to the laboratory-identified signatures to evaluate the flowpath. The majority of the flowpaths sampled had chemical signatures, which indicated mineral interflow, only 10% showed unmixed organic interflow.

The development of a non-invasive method of visualizing gene expression in larger animals could revolutionize some aspects of gene research by opening up a wider variety of animal systems to explore; some of which may be better models of human systems. Presently, most gene expression studies employ Green Fluorescent Protein (GFP) transfected into the genome of the animal system. For larger animals, an x-ray equivalent of GFP would be desirable due to the high penetrating power of x-rays. A model gene modification system is to use the Sodium (Na) Iodide Symporter (NIS) which will cause the accumulation of iodine in cells which express the NIS. To non-invasively observe the dilute iodine accumulated by the cancer cells transfected with NIS in the head of small animals, such as a rat, two synchrotron-based imaging methods were studied: K-Edge Subtraction (KES) imaging and Fluorescence Subtraction Imaging (FSI).<p> KES needs wide monochromatic x-ray beams at two energies bracketing the K-edge of the contrast agent existing or injected in the tissues. The monochromatic beam in the synchrotron facility normally is prepared by a double crystal monochromator. The appearance of the azimuthal angle (tilt error) in the double crystal monochromator creates intensity variations across the imaging field. This misalignment was studied through another two synchrotron-based imaging methods, Diffraction Enhanced Imaging (DEI) and Multi-Image Radiography (MIR), which show this problem clearly in their processed images. The detailed analysis of the effect of the tilt error, how it affects the resulting images, and how to quantify such an error were presented in the thesis. A post processing method was implemented and the artifacts caused by the improper experimental settings were discussed.<p> With the wide monochromatic beam prepared by the double crystal monochromator, a sequence of KES experiments were done and the detection limit of KES was quantified at a projected amount of 17.5mM-cm iodine in a physical model of a rat head with a radiation dose of 2.65mGy. With the raster scan of the object relative to the monochromatic pencil beam, FSI was studied to obtain higher Signal to Noise Ratio (SNR) for local area and better detection limit compared to KES. The detection limit of FSI was measured as a projected amount of 2.5mM-cm iodine in the same physical rat head with a tolerable radiation dose of 24mGy. According to the comparison of these two imaging techniques with references to imaging time and area, radiation dose, spatial resolution, and SNR, it was concluded that these two imaging techniques can be used complementarily in imaging dilute contrast material. Due to the short imaging time and large imaging area, KES is used first to provide a global view of the object, locate the area of interest, do the preliminary diagnosis, and decide whether the further FSI is necessary. Due to its high SNR for the dilute sample, FSI can be used when the area of interest is known. The combination of these two imaging techniques will be very promising and powerful. To facilitate the comparison of KES and FSI, a quality factor was developed to evaluate the performance of the imaging system.<p> The measured detection limits in our experiments are far beyond the thyroidal iodine concentration of a rat (around 1mM). To further improve the performance of KES, a bent Laue crystal monochromator was designed to do the simultaneous iodine KES imaging which overcomes the artifacts in the iodine image caused by the temporal difference for a single set of images. The designed monochromator can provide two separated x-ray beams bracketing the K-edge of iodine at the same time with a very high spatial resolution which is only depends on the source size, a very high energy resolution which can almost compete with that of the double crystal monochromator, and an acceptable photon flux.