Diplomatic summits serve as critical opportunities for national leaders to interact and mobilize the political will needed to address the world’s greatest challenges. Yet, summits have a checkered past with both successes and failures. Consequently, summit diplomacy has been equated with highly publicized photo opportunities for heads of government and grandiose communiqués with vague commitments that are never fully realized. Due to concerns about their effectiveness, legitimacy, and representation, summits are in a period of transition. These trends and challenges are especially evident in the G8, and scholars have recognized that the G8 summit has evolved to include more actors than the past. Although acknowledged as a potential site of networked governance, empirical evidence of such activity is limited. Research has yet to identify the actors involved, the structures of the relationships, and the impact of networked approaches on the preparatory process. This research specifically explores the question of how a global level network affects the priorities adopted by the G8. Using the 2010 G8 Summit as a case to examine the increased prevalence of networked activity, this study focuses on the Summit’s signature initiative: maternal, newborn and child health (MNCH). MNCH is a longstanding global problem and despite efforts such as the Millennium Development Goals, poor health outcomes persist in regions throughout the world. But to understand the selection and shaping of MNCH as the signature initiative of the 2010 G8 Summit, a mixed method approach is used. Social network analysis provides a detailed description of the actors involved in networked governance in summit diplomacy for the G8, and the structure of their relationships with one another. Qualitative data analysis of 63 in depth interviews of network members illuminates the rich and varied perspectives of the participants, which yields insight about why and how actors engage each other in order to achieve individual and collective goals. The study demonstrated that networked governance contributed to the political prioritization and substantive policy content of summit agenda items, determined during the 2010 G8 Summit preparatory process. In the case of MNCH, while the network was found to include of a diverse range of state and non-state actors, a core group of bureaucratic, political, and NGO actors played a prominent role in the selection and shaping of the MNCH initiative. Yet, the role, values and contributions of actors within the network were contested by network members during the preparatory process, demonstrating that shared goals and norms were not a dominant feature of the network. Moreover, the networked governance process has not entirely escaped the confines of geographical boundaries, given the most central actors in the network met face-to-face on a regular basis and were located in close geographical proximity. Actors from regions where MNCH problems persist most severely remained marginalized in the networked approach. While financial capital is an essential ingredient for the MNCH programs and interventions proposed for the G8 initiative, social capital was a neglected factor that is critical for building the capacity to generate new ideas and solutions. Actors within the 2010 G8 preparatory network for MNCH adopted various strategies to build and mobilize social capital. Specifically, a group of Canadian-based NGOs and an international organization formed a coalition in order to strategically advance the MNCH issue on the summit agenda. Conversely, government actors did not invest in developing and mobilizing social capital. Ultimately, informal strategies proved more valuable for breaking down hierarchical barriers and exerting influence than formal processes designed by government. Networked governance was a key factor that contributed to the political prioritization and shaping of the MNCH signature initiative for the 2010 G8 Summit and increased the inclusiveness of the summit’s preparatory process. However, while important, networked governance was not sufficient to fully explain the final outcomes – other factors such as domestic and global political contexts and the characteristics of the MNCH issue influenced the process and outcomes. Moreover, G8 summit diplomacy moved beyond being solely a state-based process in the case of MNCH, but the presence of a network of interconnected actors did not equate to better problem-solving. Although scholars and practitioners agree that integrated horizontal and vertical approaches are required for addressing the complexity of MNCH challenges, the networked approach failed to enable a move beyond conventional solutions to address the systemic nature of MNCH challenges. The findings of the study have important implications for policy and governance processes, where widespread cooperation among a network of state and non-state actors will be required for resolving intractable global problems.

Diplomatic summits serve as critical opportunities for national leaders to interact and mobilize the political will needed to address the world’s greatest challenges. Yet, summits have a checkered past with both successes and failures. Consequently, summit diplomacy has been equated with highly publicized photo opportunities for heads of government and grandiose communiqués with vague commitments that are never fully realized. Due to concerns about their effectiveness, legitimacy, and representation, summits are in a period of transition. These trends and challenges are especially evident in the G8, and scholars have recognized that the G8 summit has evolved to include more actors than the past. Although acknowledged as a potential site of networked governance, empirical evidence of such activity is limited. Research has yet to identify the actors involved, the structures of the relationships, and the impact of networked approaches on the preparatory process. This research specifically explores the question of how a global level network affects the priorities adopted by the G8. Using the 2010 G8 Summit as a case to examine the increased prevalence of networked activity, this study focuses on the Summit’s signature initiative: maternal, newborn and child health (MNCH). MNCH is a longstanding global problem and despite efforts such as the Millennium Development Goals, poor health outcomes persist in regions throughout the world. But to understand the selection and shaping of MNCH as the signature initiative of the 2010 G8 Summit, a mixed method approach is used. Social network analysis provides a detailed description of the actors involved in networked governance in summit diplomacy for the G8, and the structure of their relationships with one another. Qualitative data analysis of 63 in depth interviews of network members illuminates the rich and varied perspectives of the participants, which yields insight about why and how actors engage each other in order to achieve individual and collective goals. The study demonstrated that networked governance contributed to the political prioritization and substantive policy content of summit agenda items, determined during the 2010 G8 Summit preparatory process. In the case of MNCH, while the network was found to include of a diverse range of state and non-state actors, a core group of bureaucratic, political, and NGO actors played a prominent role in the selection and shaping of the MNCH initiative. Yet, the role, values and contributions of actors within the network were contested by network members during the preparatory process, demonstrating that shared goals and norms were not a dominant feature of the network. Moreover, the networked governance process has not entirely escaped the confines of geographical boundaries, given the most central actors in the network met face-to-face on a regular basis and were located in close geographical proximity. Actors from regions where MNCH problems persist most severely remained marginalized in the networked approach. While financial capital is an essential ingredient for the MNCH programs and interventions proposed for the G8 initiative, social capital was a neglected factor that is critical for building the capacity to generate new ideas and solutions. Actors within the 2010 G8 preparatory network for MNCH adopted various strategies to build and mobilize social capital. Specifically, a group of Canadian-based NGOs and an international organization formed a coalition in order to strategically advance the MNCH issue on the summit agenda. Conversely, government actors did not invest in developing and mobilizing social capital. Ultimately, informal strategies proved more valuable for breaking down hierarchical barriers and exerting influence than formal processes designed by government. Networked governance was a key factor that contributed to the political prioritization and shaping of the MNCH signature initiative for the 2010 G8 Summit and increased the inclusiveness of the summit’s preparatory process. However, while important, networked governance was not sufficient to fully explain the final outcomes – other factors such as domestic and global political contexts and the characteristics of the MNCH issue influenced the process and outcomes. Moreover, G8 summit diplomacy moved beyond being solely a state-based process in the case of MNCH, but the presence of a network of interconnected actors did not equate to better problem-solving. Although scholars and practitioners agree that integrated horizontal and vertical approaches are required for addressing the complexity of MNCH challenges, the networked approach failed to enable a move beyond conventional solutions to address the systemic nature of MNCH challenges. The findings of the study have important implications for policy and governance processes, where widespread cooperation among a network of state and non-state actors will be required for resolving intractable global problems.

Global demand for peacekeeping is growing, especially in Africa. The United Nations has traditionally been at the forefront of developing peacekeeping theory and practice, and remains the primary operational agency for peacekeeping in Africa. But increasing emphasis is being placed on the African Union to assume greater responsibility for peacekeeping on the continent. The AU is still comparatively new and is in the process of developing its peace and security architecture. Over the past decade, the international community has been supporting African peacekeeping, both to build AU capacity and to provide direct operational support. In 2005 the international community agreed a collective 'responsibility to protect' vulnerable civilians threatened by gross violations of their human rights. And civilian protection is increasingly included in the mandates of peacekeeping missions. Within the context of contemporary complex, multidimensional peacekeeping ('peace support'), civilian protection is not an exclusive operational objective, but is rather one of a number of mandated tasks aimed at establishing more sustainable security as part of a broader peacebuilding goal. The AU has embraced the responsibility to protect principle, adopting a constitutional commitment to protect the rights of vulnerable civilians, including through peacekeeping interventions if necessary. But how capable is the AU in practice to deliver effective peacekeeping to protect civilians? And how appropriate is international support to help realise this ambition?

The synthesis of pure tris(6-hydroxymethyl-2-pyridylmethyl)amine (H₃L₁₁) is reported for the first time. New complexes of H₃L₁₁ with copper(II), manganese(II) and iron(III) have been characterised by X-ray crystallography. Linear [Fe₃(L₁₁)₂](ClO₄)₃ reveals the tightest Fe-O-Fe angle (87.6°) and shortest Fe...Fe distance (2.834 Å) presently found for a weakly antiferromagnetically-coupled high spin alkoxide-bridged polyiron(III) system. H₃L₁₁ provides a route to various hydrophobic peralkylated TPA ligand derivatives for creating a hydrophobic pocket for the assembly of iron catalysts for the novel 1-hydroxylation of n-alkanes. New 6-py substituted TPA ligands containing methyl (L₁₅) and n-octyl (L₁₆) ether linkages were synthesised via alkylation. Two further novel 6-py substituted ligands were synthesized incorporating n-hexyl substituents on one (L₂₁) and two (L₂₂) of the py moieties. Here a urea spacer group was used to promote hydrogen–bond assisted heterolytic O-O cleavage (generation of the potent FeV=O oxidant) within the hydroxoperoxoiron(III) precursor. High spin [FeII(L)(CH₃CN)[subscript(x)]](CF₃SO₃)₂ complexes (x = 0–2, L = L₁₅,₁₆,₂₁,₂₂) were characterised in solution by ¹H NMR. The structure of [Fe(L₂₂)](CF₃SO₃)₂ reveals a distorted iron(II) centre bound to four N atoms and two urea carbonyls. Iron(II) complexes of H₃L₁₁, L₁₅,₁₆,₂₁,₂₂ and tris(6-Br)-TPA (L₂₄), were investigated for catalysis of the oxygenation of cyclohexane by H₂O₂. Reaction of the iron(II) complexes with H₂O₂ and [superscript(t)]BuOOH was followed by time-resolved EPR and UV-VIS spectrophotometry. A correlation between the observed catalytic activity and the nature of the FeIII(L)-OOR intermediates generated is apparent. A convenient ‘one-pot’ synthesis of benzene-1,3,5-triamido-tris(l-histidine methyl ester) is reported along with attempts at preparing N,N’-bis(pyridylmethyl)-1,3- diaminopropane-2-carboxylic acid (L₂₅), a new water soluble pyridine-amine ligand. The final demetallation step resulted in ligand hydrolysis to the novel amino acid; 1,3-diaminopropane- 2-carboxylic acid which was characterised as its HCl salt by X-ray crystallography.

This thesis investigates the use of binocular information for motion-in-depth (MID) perception. There are at least two different types of binocular information available to the visual system from which to derive a perception of MID: changing disparity (CD) and inter-ocular velocity differences (IOVD). In the following experiments, we manipulate the availability of CD and IOVD information in order to assess the relative influence of each on MID judgements. In the first experiment, we assessed the relative effectiveness of CD and IOVD information for MID detection, and whether the two types of binocular information are processed by separate mechanisms with differing characteristics. Our results suggest that, both CD and IOVD information can be utilised for MID detection, yet, the relative dependence on either of these types of MID information varies between observers. We then went on to explore the contribution of CD and IOVD information to time-to-contact (TTC) perception, whereby an observer judges the time at which an approaching stimulus will contact them. We confirmed that the addition of congruent binocular information to looming stimuli can influence TTC judgements, but that there is no influence from binocular information indicating no motion. Further to this, we found that observers could utilise both CD and IOVD for TTC judgements, although once again, individual receptiveness to CD and/or IOVD information varied. Thus, we demonstrate that the human visual system is able to process both CD and IOVD information, but the influence of either (or both) of these cues on an individual’s perception has been shown to be mutually independent.

Dimethylsulphoniopropionate (DMSP) and dimethylsulphoxide (DMSO) (collectively DMSP/O) are produced by marine algae, including symbiotic algae within corals. These sulphur compounds are important not only in sulphur cycle dynamics but also in potentially mediating atmospheric conditions, alleviating the effects of climate change and contributing to reef health. Most research has focused on the production of DMSP and its major degradation product, the climatically active gas, dimethylsulphide (DMS) by Acropora corals in the Great Barrier Reef. However, mechanisms for the production and release of DMSP/O by different reef taxa is poorly understood. Recently the importance of mesophotic reefs as refugia for shallow water corals has been postulated, however their role in the marine sulphur cycle is unknown. This research aimed to improve our understanding of the contemporary and climate change induced seawater and tissue production of DMSP/O in a range of reef environments and taxa. This was achieved through a combination of laboratory and field - based studies, using modern and established techniques. An effect of both elevated temperature and OA on increased tissue and seawater concentrations of DMSP/O production is reported in field and laboratory studies. Contrasting effects of benthic cover on tissue DMSP/O distributions and seawater DMSP are also noted. The importance of the physical and hydrodynamic environment on biogeochemical connectivity both within a reef and between neighbouring reefs is also focussed on. Crucially, however, the novel tissue and seawater data from mesophotic sites suggests that deeper reefs could affect the biogeochemistry of their shallow water counterparts. The key finding from this work is that climate change will result in increased seawater DMSP concentrations via two mechanisms; through the increase of cellular production of DMSP/O in all reef taxa, and by increasing the biomass of prolific DMSP producers as reefs transition to a fleshy/macroalgal assemblage. Whilst this could potentially mediate the effects of climate change, it will probably also worsen overall reef health, lead to a restructuring of reef communities from the microbial level upwards and will have possibly permanent and deleterious effects on overall ecosystem function.

No description available.

Global demand for peacekeeping is growing, especially in Africa. The United Nations has traditionally been at the forefront of developing peacekeeping theory and practice, and remains the primary operational agency for peacekeeping in Africa. But increasing emphasis is being placed on the African Union to assume greater responsibility for peacekeeping on the continent. The AU is still comparatively new and is in the process of developing its peace and security architecture. Over the past decade, the international community has been supporting African peacekeeping, both to build AU capacity and to provide direct operational support. In 2005 the international community agreed a collective ¿responsibility to protect¿ vulnerable civilians threatened by gross violations of their human rights. And civilian protection is increasingly included in the mandates of peacekeeping missions. Within the context of contemporary complex, multidimensional peacekeeping (¿peace support¿), civilian protection is not an exclusive operational objective, but is rather one of a number of mandated tasks aimed at establishing more sustainable 4 security as part of a broader peacebuilding goal. The AU has embraced the responsibility to protect principle, adopting a constitutional commitment to protect the rights of vulnerable civilians, including through peacekeeping interventions if necessary. But how capable is the AU in practice to deliver effective peacekeeping to protect civilians? And how appropriate is international support to help realise this ambition?

Introduction: Frailty represents a complex geriatric syndrome associated with elevated rates of postoperative complications as shown for several malignant entities, including head and neck cancer. A specific screening instrument to assess frailty in head and neck patients does not exist. Both the FRAIL Scale and the G8 questionnaire are well-established and easy to use as screening tools. The present study’s aim was to assess the potential of frailty screening to predict postoperative complications in head and neck patients prior to surgery. Patients and methods: We recorded demographic data, pre-existing medical conditions and clinical characteristics in a prospective cohort of 104 head and neck cancer patients undergoing major head and neck surgery and assessed frailty prospectively on the day of admission utilizing the G8 questionnaire and the FRAIL Scale. We analyzed the link between occurrence of postoperative complications up to the twenty-first postoperative day and age, frailty and other covariates using χ 2 tests and receiver operating characteristic (ROC) curves. Results: There was no significant correlation between patients’ pre-existing medical conditions and postoperative complications. Whereas chronological age alone did not predict the occurrence of postoperative complications, frailty posed the highest risk for complications. Frailty according to either the G8 questionnaire or the FRAIL Scale predicted occurrence of complications with an area under the curve (AUC) of 0.64 (p = 0.018) and 0.62 (p = 0.039) and severe complications with an AUC of 0.72 (p = 0.014) and 0.69 (p=0.031), respectively. Neither frailty score correlated with age or with each other. Conclusion: Prospective screening using the FRAIL Scale or the G8 questionnaire reliably detected frailty in our sample group. Frailty is linked to increased risk of postoperative complications. The correct prediction of severe postoperative complications as shown identifies vulnerable cases and triggers awareness of potential complications. Anticipating risk allows for a more comprehensive view of the patient and triggers decision making towards risk adjustment, and therefore a selective view of alternative treatment modalities.

Tax authorities are increasingly relying on mutual cooperation with their foreign peers to enforce more effectively their internal tax laws. After the banking scandals of 2008 and the subsequent global financial crisis, the Global Forum on Transparency and Exchange of Information for TaxPurposes has proposed the exchange of information upon request as the fiscal transparency standard. However, some measures adopted by the European Union, previous initiatives from the Organization for Economic Cooperation and Development (OECD) and, above all, the introduction of the Foreign Account Tax Compliance Act (Fatca) by the United States in 2010 have promoted the need to adopt the automatic exchange of information as the new fiscal transparency standard. Automatic exchange of information allows home countries to verify whether their taxpayers have correctly included foreign income, allowing tax authorities to have early warning of possible noncompliance cases. In February 2014, the OECD published its proposal for a new global model of automatic exchange of financial account information. The new global model contains the necessary legal instruments and due diligence and reporting procedures, mainly for financial institutions. / Las autoridades tributarias dependen cada vez más de la cooperación con sus contrapartes extranjeras para administrar más eficazmente sus leyes tributarias nacionales. Luego de los escándalos bancarios de 2008y la crisis financiera global posterior, el Foro Global sobre Transparencia e Intercambio de Información Tributaria ha impulsado el intercambio de información a requerimiento como el estándar internacional en materia de transparencia fiscal. Sin embargo, algunas medidas adoptadas por la UniónEuropea, iniciativas previas de la Organización para la Cooperación y Desarrollo Económicos (OCDE) y, sobre todo, la introducción en 2010 del«Foreign Account Tax Compliance Act» (Fatca) de los Estados Unidos han promovido la necesidad de adoptar el intercambio automático de informacióncomo nuevo estándar de transparencia fiscal internacional. El intercambio automático de información le permite a las jurisdicciones de la residencia verificar si sus contribuyentes han incluido correctamente las rentas obtenidas en el exterior, permitiéndole a las autoridades tributarias contar con alertas tempranas de posibles casos de incumplimiento. En febrero de 2014, la OCDE publicó su propuesta para un nuevo modelo global de intercambio automático de información aplicable a las cuentas mantenidas en entidades financieras. El nuevo modelo global contiene los instrumentos legales necesarios y los procedimientos de debida diligencia y reporte principalmente para las instituciones financieras.