Dissertation (Ph.D.).--University of Texas Graduate School of Biomedical Sciences at San Antonio, 2005. / Vita. Includes bibliographical references.

Thesis (Ph.D.)--University of Alabama at Birmingham, 2008. / Title from first page of PDF file (viewed on June 29, 2009). Includes bibliographical references (p. 88-97).

INTRODUÇÃO: O processo saúde-doença está intrinsecamente conectado com as condições concretas de vida e com as diversas realidades sociais, acarretando o forte vínculo entre a situação de saúde e os fatores históricos, sociais, econômicos, culturais e biológicos. A formulação sobre Determinantes Sociais da Saúde (DSS) busca ampliar o enfoque sobre as condições de vida e bem-estar, salientando a distribuição de renda, as condições de vida e trabalho, as redes de suporte social, entre outros, como fatores que afetam a qualidade de vida. Os DSS buscam, assim, evitar a análise fragmentada, englobando a concepção de Determinantes Estruturais. Estes procuram compreender as condições de distribuição de riqueza, poder e prestígio na origem dos problemas de saúde. Assim, a estrutura de classes sociais, a distribuição de renda e o preconceito de gênero e raça são considerados na proposição de políticas de saúde. OBJETIVO: Sistematizar o conhecimento a respeito dos DSS e seus componentes Estruturais e Intermediários, segundo o potencial para contribuir na elaboração de políticas sociais e de saúde. MÉTODO: Trata-se de uma pesquisa de revisão de escopo (Scoping Review), metodologia que amplia e aprofunda o mapeamento e a síntese do conhecimento. As etapas foram: identificação da questão de pesquisa e dos estudos relevantes; seleção dos estudos; extração de dados; separação, sumarização, relatório e comunicação dos resultados. Foram pesquisadas as seguintes bases de dados eletrônicas: Web of Science, CINAHL, Scopus, LILACS e Pub-Med, que engloba o MEDLINE. Adicionalmente, foi realizado levantamento específico nas revistas: International Journal of Epidemiology, Journal of Epidemiology and Community Health, American Journal of Public Health e American Journal of Epidemiology. RESULTADOS: Após a retirada das duplicatas, foram localizados 752 artigos; e após a triagem, 19 artigos foram analisados em profundidade. Dentre os países nos quais as pesquisas selecionadas foram desenvolvidas, destacaram-se Estados Unidos e Inglaterra com seis e quatro publicações respectivamente (31,6% e 21%) seguidos de três publicações no Canadá (15,7%), duas no Brasil (10,5%), duas na Nova Zelândia (10,5%), duas na Austrália (10,5%) e uma no México (5,2%). As discussões sobre os Determinantes Estruturais da saúde são mais recentes. A análise permitiu tratar das diferenças entre termos comumente utilizados, como desigualdade, disparidade e iniquidade. Os marcadores sociais da diferença mais problematizados na formulação dos DSS Estruturais foram: racismo gênero, classe social e situação migratória. Por serem os marcadores sociais mutuamente construídos, a perspectiva teórica da interseccionalidade foi apresentada como recurso metodológico para entender suas inter-relações. CONCLUSÃO: Foi possível identificar neste trabalho uma agenda síntese que perpassa ações na área econômica, propondo a redistribuição da riqueza; políticas públicas intersetoriais e mudanças no arcabouço jurídico, destacando que os determinantes sociais são mais bem compreendidos quando se reconhece a dialética entre contextos específicos e os macrodeterminantes políticos e econômicos, identificando os diferentes significados e consequências para a saúde / INTRODUCTION: The health-disease process is intrinsically connected with concrete conditions of life and with the diverse social realities, which brings about the strong ties between the health situation and historical, social, economical, cultural, and biological factors. The formulation of Social Determinants of Health (SDH) seeks to broaden the focus on conditions of life and well-being, emphasizing the distribution of income, the work and life conditions, the net of social support, among other factors that affected the quality of life. SDH seek, in this way, to avoid a fragmented analysis, embodying the conception of Structural Determinants, which seek to comprehend the conditions of distribution of wealth, power, and prestige in the origins of health problems. Thus, the structure of social classes, the distribution of income, and the prejudice of gender and race are taken into account in the proposition of health policies. OBJECTIVE: systematizing knowledge about the SDH and their structural components, according to the potential to contribute in the elaboration of social and health policies. METHODOLOGY: The following research employs the Scoping Review Methodology, which enlarges and deeps the mapping and the synthesis of knowledge. The phases of our work were the following: identification of the research issue and relevant studies; selection of the studies; extraction of data; division, summarization, reports, and communication of results. The following electronic databases were researched: Web of Science, CINAHL, Scopus, LILACS, and Pub-Med, which comprehends MEDLINE. Additionally, specific journals were surveyed: International Journal of Epidemiology, Journal of Epidemiology and Community Health, American Journal of Public Health, and American Journal of Epidemiology. OUTCOMES: After removing the duplicates, 752 articles were found, and after the screening 19 articles were analyzed in depth. Among the countries in which the selected researches were conducted, the following are noteworthy: England and the USA with four and five publications respectively (21% and 26,3%), followed by three publications in Canada (15,7%), two in Brazil (10,5%), two in New Zealand (10,5%), two in Australia (10,5%) and one in México (5,2%). The discussions on Structural Determinants of Health are more recent. The analysis allowed us to treat the differences among terms commonly used, such as inequality, disparity, and inequity. The social markers of difference more problematized in the formulation of the Structural SDH were racism, gender, social class, and migration situation. For being social markers mutually built, the theoretical perspective of intersectionality was presented as a methodological resource to understand its inter-relations. CONCLUSION: This work was able to identify a synthesis-agenda, which passes through actions in the economical field, proposing the redistribution of wealth, intersectoral public policies, and changes in the juridical frame, emphasizing that the social determinants are better comprehended when the dialectics between specific contexts and the political-economical macro-determinants are acknowledged, identifying the different meanings and consequences for Health

Dissertation (Ph.D.)--University of South Florida, 2007. / Title from PDF of title page. Document formatted into pages; contains 155 pages. Includes vita. Includes bibliographical references.

O objetivo do estudo foi analisar a relação dos marcadores de desigualdade em saúde, com destaque para a posição socioeconômica, com a autoavaliação da saúde bucal e da saúde geral da população adulta brasileira em 2013. Estudaram-se 59.758 indivíduos com 18 anos ou mais de idade, que participaram da Pesquisa Nacional de Saúde 2013, um inquérito domiciliar de base populacional. As variáveis dependentes do estudo foram a autoavaliação da saúde bucal (dentes e gengivas) e autoavaliação da saúde geral, sendo ambas analisadas como positiva, regular e negativa. As variáveis independentes foram os marcadores de desigualdade em saúde (cor ou raça, região de residência, nível de escolaridade completo, renda domiciliar per capita e classe social). Odds ratios (OR) brutos e ajustados e intervalos de confiança de 95% (IC 95%) foram calculados usando modelos de regressão logística multinomial. Os resultados referentes à autoavaliação da saúde geral foram estratificados segundo o sexo. A prevalência da autoavaliação de saúde bucal positiva foi 67,4%, 26,7% para regular e 5,9% para negativa, enquanto para a saúde geral foram 66,2%, 28,0% e 5,8%, respectivamente. As mulheres avaliam pior sua saúde geral do que os homens. Após ajuste pelas variáveis de controle, as chances de autoavaliar a saúde bucal como negativa foi significativamente mais elevadas entre os indivíduos com renda domiciliar per capita de até um salário mínimo (OR=4,71; IC95%: 2,84-7,83), sem escolaridade (OR=3,28; IC95%: 2,34-4,61), da classe social destituídos de ativos (OR=3,03; IC95%: 2,12-4,32) e residentes da região nordeste (OR=1,50; IC95%: 1,19-1,89). Em relação à autoavaliação da saúde geral nos homens, as chances de avaliar pior foram significativamente mais elevadas entre os indivíduos de menor renda domiciliar per capita, com pior nível de escolaridade, pessoas fora da força de trabalho, moradores das regiões Nordeste e Norte e que se declararam pardos e pretos. Enquanto nas mulheres, as chances de avaliar pior seu estado de saúde geral foram maiores entre as de pior nível de escolaridade, menor renda domiciliar per capita, que se encontravam fora da força de trabalho, que se declararam não brancas e moradoras das regiões Nordeste e Norte do país. A tipologia de classe social utilizada neste estudo foi válida para capturar desigualdades na autopercepção da saúde bucal e da saúde geral de adultos, à semelhança da renda domiciliar per capita e da escolaridade, com diferenciais apenas na força de associação, a depender do desfecho e do sexo. A compreensão da relação dos marcadores de desigualdade da autoavaliação da saúde bucal e da saúde geral pode levar ao melhor direcionamento de políticas públicas para grupos sociais mais vulneráveis, contribuindo para a redução das iniquidades em saúde que persistem no Brasil. / The objective of the study was to analyze the relationship between health inequality markers, with emphasis on the socioeconomic position, with the self-assessment of oral health and general health of the Brazilian adult population in 2013. A total of 59,758 individuals aged 18 years and older participated in the National Health Survey 2013, a population-based household survey. The dependent variables on the study were selfassessment of oral health (teeth and gums) and self-assessment of general health, both of which were analyzed as positive, regular and negative. The independent variables were the markers of health inequality (color or race, residence area, education, per capita household income and social class). Crude and adjusted odds ratios (OR) and 95% confidence intervals (95% CI) were computed using multinomial logistic regression models. Results regarding general self-rated health were stratified by gender. The prevalence of self-assessment of positive oral health was 67.4%, 26.7% for regular and 5.9% for negative, while for general health were 66.2%, 28.0% and 5.8%, respectively. Women evaluate their overall health worse than men. After adjustment, the probability of rating their oral health as negative was significantly higher among individuals with a per capita household income up to a minimum wage (OR=4.71, 95%CI: 2.84-7.83), no schooling (OR=3.28, 95%CI: 2.34-4.61), of the social class devoid of assets (OR=3.03, 95%CI: 2.12-4.32) and living in the northeast region (OR=1.50, 95%CI: 1.19-1.89). Regarding the self-assessment of general health in men, the odds of evaluating worse were significantly higher among individuals with lower per capita household income, with lower educational level, people outside the work force, residents of the Northeast and North regions, and declared themselves brown and black. While in women, the chances of a worse evaluation of their general health status were higher among those with the lowest level of schooling, lower per capita household income, who were outside the work force, who declared themselves as nonwhites and residents of the Northeast and North regions of the country. The social class typology used in this study was valid to capture inequalities in self-perception of oral health and general health of adults, similar to per capita household income and education, with differentials only in strength of association, depending on the outcome and gender. Understanding the relationship between the inequality markers of oral health selfassessment and general health can lead to improvement of public policies to vulnerable social groups, contributing to the reduction of health inequities that persist in Brazil.

Objective: To determine whether continuity of care (COC) reduces emergency department (ED) visits and/or readmission in adolescents with psychiatric disorders. Methods: A retrospective cohort of adolescents discharged with psychiatric disorder between April 1, 2002 and March 1, 2004 was identified using hospital administrative databases. Good COC was defined as at least one aftercare contact in 30 days. Confounding by patient characteristics was adjusted for by propensity-score-matching of good and poor COC adolescents. Cox PH was used to analyze time to outcome. Results: 48.77% of adolescents had good COC. 38.39% of adolescents had ED visit or readmission in the year post-discharge. Good COC increased risk of readmission (HR = 1.38 (1.14 – 1.66)), but not of ED visits (HR = 1.14 (0.95 – 1.37)). Conclusions: COC increased risk of readmission by 38% but did not increase risk of ED visits. These findings are contextualized. Implications to adolescent mental health service delivery are discussed.

Objective: To determine whether continuity of care (COC) reduces emergency department (ED) visits and/or readmission in adolescents with psychiatric disorders. Methods: A retrospective cohort of adolescents discharged with psychiatric disorder between April 1, 2002 and March 1, 2004 was identified using hospital administrative databases. Good COC was defined as at least one aftercare contact in 30 days. Confounding by patient characteristics was adjusted for by propensity-score-matching of good and poor COC adolescents. Cox PH was used to analyze time to outcome. Results: 48.77% of adolescents had good COC. 38.39% of adolescents had ED visit or readmission in the year post-discharge. Good COC increased risk of readmission (HR = 1.38 (1.14 – 1.66)), but not of ED visits (HR = 1.14 (0.95 – 1.37)). Conclusions: COC increased risk of readmission by 38% but did not increase risk of ED visits. These findings are contextualized. Implications to adolescent mental health service delivery are discussed.

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro / Esta dissertação buscou uma apreciação crítica e pragmática da relação entre desigualdade socioeconômica e obesidade abdominal, em resposta a proposição internacional de monitoramento das desigualdades em saúde e a escassez de estudos desta natureza relativos à obesidade abdominal. Dois artigos foram elaborados a fim de estimar o grau de desigualdade educacional na ocorrência de obesidade abdominal e revisar os estudos de associação entre posição socioeconômica e obesidade abdominal. O primeiro artigo utilizou o índice angular de desigualdade e o índice relativo de desigualdade em dados seccionais de 3.117 participantes da linha de base do Estudo Pró-Saúde, 1999-2001, e o segundo artigo abarcou os resultados de estudos conduzidos em população adulta no Brasil. Os índices de desigualdade resumiram a tendência monotônica e inversa observada entre escolaridade e obesidade abdominal na população feminina, proporcionando estimativas quantitativas desta desigualdade (artigo 1). Em concordância, observou-se que a associação entre indicadores de posição socioeconômica e obesidade abdominal foi majoritariamente inversa entre as mulheres, principalmente com relação à escolaridade, e estatisticamente não significativa entre os homens (artigo 2). Tal cenário epidemiológico evidencia que a obesidade abdominal tem afetado desproporcionalmente as mulheres de posição socioeconômica mais baixa e que a desigualdade de gênero na prevalência de obesidade abdominal tende a aumentar com menor posição socioeconômica. Em suma, a presente dissertação visou à produção de conhecimento epidemiológico relevante ao enfrentamento das desigualdades em saúde, com o objetivo premente de subsidiar políticas públicas de fato realizáveis e individualmente aceitáveis. / This dissertation sought to a critical and pragmatic assessment of the relationship between socioeconomic inequality and abdominal obesity in response to international proposition of health inequalities monitoring and to lack of studies of this nature relating to abdominal obesity. Two articles were prepared to -estimate the level of educational inequality in the occurrence of abdominal obesity, and review the association studies between socioeconomic position and abdominal obesity. The first article used the slope index of inequality and the relative index of inequality in the sectional data of 3.117 participants in the baseline of the Pró-Saúde Study, 1999-2001; and the second article encompassed the results of the studies conducted in the adult population in Brazil. The inequality indexes summarized strictly monotonic and inverse trend between educational achievement and abdominal obesity in the female population, providing quantitative estimates of this inequality (Article 1). Accordingly, we found that the association between socioeconomic position indicators and abdominal obesity was mostly reversed among women, especially regarding education, and statistically not significant among men (Article 2). This epidemiological scenario shows that abdominal obesity has disproportionately affected women of the lower socioeconomic position, and gender inequality in the prevalence of abdominal obesity tends to increase with lower socioeconomic position. In short, this dissertation aimed at the production of relevant epidemiological knowledge to addressing health inequalities, with the targeted of subsidize public policies feasible and individually acceptable.

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro / Esta dissertação buscou uma apreciação crítica e pragmática da relação entre desigualdade socioeconômica e obesidade abdominal, em resposta a proposição internacional de monitoramento das desigualdades em saúde e a escassez de estudos desta natureza relativos à obesidade abdominal. Dois artigos foram elaborados a fim de estimar o grau de desigualdade educacional na ocorrência de obesidade abdominal e revisar os estudos de associação entre posição socioeconômica e obesidade abdominal. O primeiro artigo utilizou o índice angular de desigualdade e o índice relativo de desigualdade em dados seccionais de 3.117 participantes da linha de base do Estudo Pró-Saúde, 1999-2001, e o segundo artigo abarcou os resultados de estudos conduzidos em população adulta no Brasil. Os índices de desigualdade resumiram a tendência monotônica e inversa observada entre escolaridade e obesidade abdominal na população feminina, proporcionando estimativas quantitativas desta desigualdade (artigo 1). Em concordância, observou-se que a associação entre indicadores de posição socioeconômica e obesidade abdominal foi majoritariamente inversa entre as mulheres, principalmente com relação à escolaridade, e estatisticamente não significativa entre os homens (artigo 2). Tal cenário epidemiológico evidencia que a obesidade abdominal tem afetado desproporcionalmente as mulheres de posição socioeconômica mais baixa e que a desigualdade de gênero na prevalência de obesidade abdominal tende a aumentar com menor posição socioeconômica. Em suma, a presente dissertação visou à produção de conhecimento epidemiológico relevante ao enfrentamento das desigualdades em saúde, com o objetivo premente de subsidiar políticas públicas de fato realizáveis e individualmente aceitáveis. / This dissertation sought to a critical and pragmatic assessment of the relationship between socioeconomic inequality and abdominal obesity in response to international proposition of health inequalities monitoring and to lack of studies of this nature relating to abdominal obesity. Two articles were prepared to -estimate the level of educational inequality in the occurrence of abdominal obesity, and review the association studies between socioeconomic position and abdominal obesity. The first article used the slope index of inequality and the relative index of inequality in the sectional data of 3.117 participants in the baseline of the Pró-Saúde Study, 1999-2001; and the second article encompassed the results of the studies conducted in the adult population in Brazil. The inequality indexes summarized strictly monotonic and inverse trend between educational achievement and abdominal obesity in the female population, providing quantitative estimates of this inequality (Article 1). Accordingly, we found that the association between socioeconomic position indicators and abdominal obesity was mostly reversed among women, especially regarding education, and statistically not significant among men (Article 2). This epidemiological scenario shows that abdominal obesity has disproportionately affected women of the lower socioeconomic position, and gender inequality in the prevalence of abdominal obesity tends to increase with lower socioeconomic position. In short, this dissertation aimed at the production of relevant epidemiological knowledge to addressing health inequalities, with the targeted of subsidize public policies feasible and individually acceptable.

Yes / Bradford, one of the most deprived cities in the United Kingdom, has a wide range of public health problems associated with socioeconomic deprivation, including an infant mortality rate almost double that for England and Wales. Infant mortality is highest for babies of Pakistani origin, who comprise almost half the babies born in Bradford. The Born in Bradford cohort study aims to examine environmental, psychological and genetic factors that impact on health and development perinatally, during childhood and subsequent adult life, and those that influence their parents' health and wellbeing. This protocol outlines methods for the recruitment phase of the study. METHODS: Most Bradford women attend for antenatal care and give birth at the Bradford Royal Infirmary, which has approximately 5,800 births per year. Women are eligible for recruitment if they plan to give birth here. Babies born from March 2007 are eligible to participate, recruitment is planned to continue until 2010. Fathers of babies recruited are invited to participate. Women are usually recruited when they attend for a routine oral glucose tolerance test at 26-28 weeks gestation. Recruitment of babies is at birth. Fathers are recruited whenever possible during the antenatal period, or soon after the birth. The aim is to recruit 10,000 women, their babies, and the babies' fathers. At recruitment women have blood samples taken, are interviewed to complete a semi-structured questionnaire, weighed, and have height, arm circumference and triceps skinfold measured. Umbilical cord blood is collected at birth. Within two weeks of birth babies have their head, arm and abdominal circumference measured, along with subscapular and triceps skinfold thickness. Fathers self-complete a questionnaire at recruitment, have height and weight measured, and provide a saliva sample. Participants are allocated a unique study number. NHS numbers will be used to facilitate record linkage and access to routine data. A wide range of hospital and community sources is being accessed to provide data for the women and children. Data are checked for accuracy and consistency. CONCLUSION: Born in Bradford will increase understanding of the factors that contribute to health and wellbeing, and identify factors that influence differences in them between people of Pakistani and European origin.