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The Global ETD Search service is a free service for researchers
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Showing 131 to 140 of 140 (0.073 seconds)Spelling suggestions: "subject:"dealth anda disease"" "subject:"dealth ando disease""
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Klinoskop: Zeitschrift der Klinikum Chemnitz gGmbH17 October 2019 (has links)
Das Klinoskop ist die Firmenzeitschrift des Klinikums Chemnitz für Mitarbeiter, Patienten, Angehörige und für unsere Partner. Es erscheint in vier bis fünf Ausgaben pro Jahr in einem Umfang von 40 bis 92 Seiten im Vollfarbdruck.Unsere Firmenzeitschrift wurde seit 2006 von einer qualitativen Mitarbeiterinformation kontinuierlich zu einem relevanten Informationsmedium für unsere Partner wie niedergelassene Ärzte weiterentwickelt. Parallel soll das Klinoskop eine Publikation sein, mit der Patienten und Angehörige einen informativen Zugang zu Ihrem Klinkum Chemnitz erhalten. Damit möchten wir auch unseren Anspruch einer offenen Kommunikation unterlegen. / The Klinoskop is the corporate magazine of the Klinikum Chemnitz for our staff, patients and their family members as well as for our cooperating partners. It is published in full colour, with four or five issues per year, and each issue contains between 40 and 92 pages. Since 2006, our corporate magazine has been continuously refined from a high-quality publication for our staff to the relevant information medium for our partners, in particular physicians in private practice. At the same time, the Klinoskop is intended to be a publication that provides patients and their relatives with more detailed information about their Hospital in Chemnitz. This also helps us to emphasize our intentions of fostering open communication.
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| 132 |
Klinoskop: Zeitschrift der Klinikum Chemnitz gGmbH17 October 2019 (has links)
Das Klinoskop ist die Firmenzeitschrift des Klinikums Chemnitz für Mitarbeiter, Patienten, Angehörige und für unsere Partner. Es erscheint in vier bis fünf Ausgaben pro Jahr in einem Umfang von 40 bis 92 Seiten im Vollfarbdruck.Unsere Firmenzeitschrift wurde seit 2006 von einer qualitativen Mitarbeiterinformation kontinuierlich zu einem relevanten Informationsmedium für unsere Partner wie niedergelassene Ärzte weiterentwickelt. Parallel soll das Klinoskop eine Publikation sein, mit der Patienten und Angehörige einen informativen Zugang zu Ihrem Klinkum Chemnitz erhalten. Damit möchten wir auch unseren Anspruch einer offenen Kommunikation unterlegen. / The Klinoskop is the corporate magazine of the Klinikum Chemnitz for our staff, patients and their family members as well as for our cooperating partners. It is published in full colour, with four or five issues per year, and each issue contains between 40 and 92 pages. Since 2006, our corporate magazine has been continuously refined from a high-quality publication for our staff to the relevant information medium for our partners, in particular physicians in private practice. At the same time, the Klinoskop is intended to be a publication that provides patients and their relatives with more detailed information about their Hospital in Chemnitz. This also helps us to emphasize our intentions of fostering open communication.
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| 133 |
Klinoskop: Zeitschrift der Klinikum Chemnitz gGmbH17 October 2019 (has links)
Das Klinoskop ist die Firmenzeitschrift des Klinikums Chemnitz für Mitarbeiter, Patienten, Angehörige und für unsere Partner. Es erscheint in vier bis fünf Ausgaben pro Jahr in einem Umfang von 40 bis 92 Seiten im Vollfarbdruck.Unsere Firmenzeitschrift wurde seit 2006 von einer qualitativen Mitarbeiterinformation kontinuierlich zu einem relevanten Informationsmedium für unsere Partner wie niedergelassene Ärzte weiterentwickelt. Parallel soll das Klinoskop eine Publikation sein, mit der Patienten und Angehörige einen informativen Zugang zu Ihrem Klinkum Chemnitz erhalten. Damit möchten wir auch unseren Anspruch einer offenen Kommunikation unterlegen. / The Klinoskop is the corporate magazine of the Klinikum Chemnitz for our staff, patients and their family members as well as for our cooperating partners. It is published in full colour, with four or five issues per year, and each issue contains between 40 and 92 pages. Since 2006, our corporate magazine has been continuously refined from a high-quality publication for our staff to the relevant information medium for our partners, in particular physicians in private practice. At the same time, the Klinoskop is intended to be a publication that provides patients and their relatives with more detailed information about their Hospital in Chemnitz. This also helps us to emphasize our intentions of fostering open communication.
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| 134 |
Klinoskop: Zeitschrift der Klinikum Chemnitz gGmbH17 October 2019 (has links)
Das Klinoskop ist die Firmenzeitschrift des Klinikums Chemnitz für Mitarbeiter, Patienten, Angehörige und für unsere Partner. Es erscheint in vier bis fünf Ausgaben pro Jahr in einem Umfang von 40 bis 92 Seiten im Vollfarbdruck.Unsere Firmenzeitschrift wurde seit 2006 von einer qualitativen Mitarbeiterinformation kontinuierlich zu einem relevanten Informationsmedium für unsere Partner wie niedergelassene Ärzte weiterentwickelt. Parallel soll das Klinoskop eine Publikation sein, mit der Patienten und Angehörige einen informativen Zugang zu Ihrem Klinkum Chemnitz erhalten. Damit möchten wir auch unseren Anspruch einer offenen Kommunikation unterlegen. / The Klinoskop is the corporate magazine of the Klinikum Chemnitz for our staff, patients and their family members as well as for our cooperating partners. It is published in full colour, with four or five issues per year, and each issue contains between 40 and 92 pages. Since 2006, our corporate magazine has been continuously refined from a high-quality publication for our staff to the relevant information medium for our partners, in particular physicians in private practice. At the same time, the Klinoskop is intended to be a publication that provides patients and their relatives with more detailed information about their Hospital in Chemnitz. This also helps us to emphasize our intentions of fostering open communication.
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Klinoskop: Zeitschrift der Klinikum Chemnitz gGmbH22 March 2022 (has links)
Das Klinoskop ist die Firmenzeitschrift des Klinikums Chemnitz für Mitarbeiter, Patienten, Angehörige und für unsere Partner. Es erscheint in vier bis fünf Ausgaben pro Jahr in einem Umfang von 40 bis 92 Seiten im Vollfarbdruck.Unsere Firmenzeitschrift wurde seit 2006 von einer qualitativen Mitarbeiterinformation kontinuierlich zu einem relevanten Informationsmedium für unsere Partner wie niedergelassene Ärzte weiterentwickelt. Parallel soll das Klinoskop eine Publikation sein, mit der Patienten und Angehörige einen informativen Zugang zu Ihrem Klinkum Chemnitz erhalten. Damit möchten wir auch unseren Anspruch einer offenen Kommunikation unterlegen. / The Klinoskop is the corporate magazine of the Klinikum Chemnitz for our staff, patients and their family members as well as for our cooperating partners. It is published in full colour, with four or five issues per year, and each issue contains between 40 and 92 pages. Since 2006, our corporate magazine has been continuously refined from a high-quality publication for our staff to the relevant information medium for our partners, in particular physicians in private practice. At the same time, the Klinoskop is intended to be a publication that provides patients and their relatives with more detailed information about their Hospital in Chemnitz. This also helps us to emphasize our intentions of fostering open communication.
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| 136 |
Klinoskop: Zeitschrift der Klinikum Chemnitz gGmbH05 April 2011 (has links)
Das Klinoskop ist die Firmenzeitschrift des Klinikums Chemnitz für Mitarbeiter, Patienten, Angehörige und für unsere Partner. Es erscheint in vier bis fünf Ausgaben pro Jahr in einem Umfang von 40 bis 92 Seiten im Vollfarbdruck.
Unsere Firmenzeitschrift wurde seit 2006 von einer qualitativen Mitarbeiterinformation kontinuierlich zu einem relevanten Informationsmedium für unsere Partner wie niedergelassene Ärzte weiterentwickelt. Parallel soll das Klinoskop eine Publikation sein, mit der Patienten und Angehörige einen informativen Zugang zu Ihrem Klinkum Chemnitz erhalten. Damit möchten wir auch unseren Anspruch einer offenen Kommunikation unterlegen.
(Erscheinen eingestellt) / The Klinoskop is the corporate magazine of the Klinikum Chemnitz for our staff, patients and their family members as well as for our cooperating partners. It is published in full colour, with four or five issues per year, and each issue contains between 40 and 92 pages.
Since 2006, our corporate magazine has been continuously refined from a high-quality publication for our staff to the relevant information medium for our partners, in particular physicians in private practice.
At the same time, the Klinoskop is intended to be a publication that provides patients and their relatives with more detailed information about their Hospital in Chemnitz. This also helps us to emphasize our intentions of fostering open communication.
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Chronopsychobiologische Pilotstudie zur objektiven Bestimmung funktioneller GesundheitszuständeAnske, Ute 15 September 2003 (has links)
1. Unterschiedliche Definitionen der Gesundheit mit verschiedenen Betrachtungsweisen (WHO: Der Mensch eine biopsychosoziale Einheit. Schulmedizin: ohne klinischen und paraklinischen Befund mit Orientierung an kritikbedürftigen Referenzmittelwerten) führt bei Fachleuten, Behörden und Laien zu Verwirrungen, wenn es um die Beurteilung gesundheitlicher Schäden geht. 2. Es wurde die Aufgabe gestellt zu prüfen, welche der beiden Definitionen der Realität näher kommt. 3. Mittels der chronopsychobiologischen Regulationsdiagnostik, des Dreiphasenentspannungstests (Hecht und Balzer 2001), wurden unter dem Aspekt der beiden Gesundheitsdefinitionen drei Gruppen untersucht (je 40 Probanden). - klinisch Gesunde (klinisch Gesunde nach Schulmedizin ) - Gesunde nach Definition der WHO - Probanden mit nichtorganische Insomnie (ohne pathologische klinische und paraklinische Befunde) 4. Die mit den verwendeten Methoden gewonnenen Daten wiesen aus, dass zwischen den klinisch Gesunden und den Probanden mit nichtorganischer Insomnie weitgehend größere Ähnlichkeiten bestehen. Beide Gruppen zeigten aber zu der Gruppe der Gesunden nach WHO-Definition, welche die biopsychosoziale Einheit des Menschen berücksichtigt, noch hochsignifikante Unterschiede. Die Gruppe der klinisch Gesunden kann daher auf Grund unserer Ergebnisse nicht den Anspruch erheben, real gesund zu sein. 5. Mit der Bezugnahme auf die Internationale Klassifikation der Krankheiten (ICD 10F) haben die von uns untersuchten klinisch Gesunden und die nichtorganischen Insomniker eine mehr oder weniger stark ausgeprägte Symptomatik von psychischen Störungen. Dies müsste bei der Beurteilung von Schadstoff-, Lärm-, und EMF-Wirkungen auf den Menschen, wie auch bei den klinisch-pharmakoloischen Untersuchungen beachtet werden. Die in der Arbeit erzielten Ergebnisse bedürfen durch weitere Untersuchungen eine Fundierung. Sie signalisieren aber sowohl unter praktischen als auch unter theoretischen Aspekten einen dringenden Forschungsbedarf. / 1. Differing definitions of health using different criterea (WHO: The human being as a bio- psycho-social unit versus classical medicine: without clinical and paraclinical results based on suspect reference values) bring confusion to experts, authorities and laymen when assessing health damages. 2. The given task was to check which of the two definitions is closer to reality. 3. Using the chrono-psycho-biological diagnostic of regulation, the three-phase-relaxation test (Hecht and Balzer 2001), three groups were examined considering the aspects of the two health definitions (40 test subjects in the study group). - clinically healthy (clinically healthy per classical medicine definition) - healthy per definition of the WHO - test persons with non organic insomnia (i.e. no pathological or paraclinical findings) 4. The data gained from the employed methods revealed bigger similarities between clinically healthy persons and those with non organic insomnia. Both groups still showed highly significant differences to the group which fulfils the definition of the WHO regarding a human as a bio-psycho-social unit. As a result of this study, persons, though classified as "clinically healthy" might nevertheless not absolutely be healthy in reality. 5. In reference to the international classification of illnesses (ICD 10 F) the groups examined, both of clinically healthy and those with non organic insomnia, have more or less severe psychological symptoms. This should be taken into account when assessing the effects of pollution, noise, and EMF as well as clinical pharmacological studies. These present findings still need broader confirmation by further investigations. However, they clearly indicate, for practical and theoretical considerations, an urgent need for further research.
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BIRTHWEIGHT AND SUSCEPTIBILITY TO CHRONIC DISEASEIssa Al Salmi Unknown Date (has links)
The thesis examines the relationship of birthweight to risk factors and markers, such as proteinuria and glomerular filtration rate, for chronic disease in postnatal life. It made use of the Australian Diabetes, Obesity and Lifestyle Study (AusDiab). The AusDiab study is a cross sectional study where baseline data on 11,247 participants were collected in 1999-2000. Participants were recruited from a stratified sample of Australians aged ≥ 25 years, residing in 42 randomly selected urban and non-urban areas (Census Collector Districts) of the six states of Australia and the Northern Territory. The AusDiab study collected an enormous amount of clinical and laboratory data. During the 2004-05 follow-up AusDiab survey, questions about birthweight were included. Participants were asked to state their birthweight, the likely accuracy of the stated birthweight and the source of their stated birthweight. Four hundred and twelve chronic kidney disease (CKD) patients were approached, and 339 agreed to participate in the study. The patients completed the same questionnaire. Medical records were reviewed to check the diagnoses, causes of kidney trouble and SCr levels. Two control subjects, matched for gender and age, were selected for each CKD patient from participants in the AusDiab study who reported their birthweight. Among 7,157 AusDiab participants who responded to the questionnaire, 4,502 reported their birthweights, with a mean (standard deviation) of 3.4 (0.7) kg. The benefit and disadvantages of these data are discussed in chapter three. The data were analysed for the relationship between birthweight and adult body size and composition, disorders of glucose regulation, blood pressure, lipid abnormalities, cardiovascular diseases and glomerular filtration rate. Low birthweight was associated with smaller body build and lower lean mass and total body water in both females and males. In addition low birthweight was associated with central obesity and higher body fat percentage in females, even after taking into account current physical activity and socioeconomic status. Fasting plasma glucose, post load glucose and glycosylated haemoglobin were strongly and inversely correlated with birthweight. In those with low birthweight (< 2.5 kg), the risks for having impaired fasting glucose, impaired glucose tolerance, diabetes and all abnormalities combined were increased by 1.75, 2.22, 2.76 and 2.28 for females and by 1.40, 1.32, 1.98 and 1.49 for males compared to those with normal birthweight (≥ 2.5 kg), respectively. Low birthweight individuals were at higher risk for having high blood pressure ≥ 140/90 mmHg and ≥ 130/85 mmHg compared to those with normal birthweight. People with low birthweight showed a trend towards increased risk for high cholesterol (≥ 5.5 mmol/l) compared to those of normal birthweight. Females with low birthweight had increased risk for high low density lipoprotein cholesterol (≥ 3.5 mmol/l) and triglyceride levels (≥ 1.7 mmol/l) when compared to those with normal birthweight. Males with low birthweight exhibited increased risk for low levels of high density lipoprotein cholesterol (<0.9 mmol/l) than those with normal birthweight. Females with low birthweight were at least 1.39, 1.40, 2.30 and 1.47 times more likely to have angina, coronary artery disease, stroke and overall cardiovascular diseases respectively, compared to those ≥ 2.5 kg. Similarly, males with low birthweight were 1.76, 1.48, 3.34 and 1.70 times more likely to have angina, coronary artery disease, stroke and overall cardiovascular diseases compared to those ≥ 2.5 kg, respectively. The estimated glomerular filtration rate was strongly and positively associated with birthweight, with a predicted increase of 2.6 ml/min (CI 2.1, 3.2) and 3.8 (3.0, 4.5) for each kg of birthweight for females and males, respectively. The odd ratio (95% confidence interval) for low glomerular filtration rate (<61.0 ml/min for female and < 87.4 male) in people of low birthweight compared with those of normal birthweight was 2.04 (1.45, 2.88) for female and 3.4 (2.11, 5.36) for male. One hundred and eighty-nineCKD patients reported their birthweight; 106 were male. Their age was 60.3(15) years. Their birthweight was 3.27 (0.62) kg, vs 3.46 (0.6) kg for their AusDiab controls, p<0.001 and the proportions with birthweight<2.5 kg were 12.17% and 4.44%, p<0.001. Among CKD patients, 22.8%, 21.7%, 18% and 37.6% were in CKD stages 2, 3, 4 and 5 respectively. Birthweights by CKD stage and their AusDiab controls were as follows: 3.38 (0.52) vs 3.49 (0.52), p=0.251 for CKD2; 3.28 (0.54) vs 3.44 (0.54), p=0.121 for CKD3; 3.19 (0.72) vs 3.43 (0.56), p= 0.112 for CKD4 and 3.09 (0.65) vs 3.47 (0.67), p<0.001 for CKD5. The results demonstrate that in an affluent Western country with a good adult health profile, low birthweight people were predisposed to higher rates of glycaemic dysregulation, high blood pressure, dyslipidaemia, cardiovascular diseases and lower glomerular filtration rate in adult life. In all instances it would be prudent to adopt policies of intensified whole of life surveillance of lower birthweight people, anticipating this risk. The general public awareness of the effect of low birthweight on development of chronic diseases in later life is of vital importance. The general public, in addition to the awareness of people in medical practice of the role of low birthweight, will lead to a better management of this group of our population that is increasingly surviving into adulthood.
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BIRTHWEIGHT AND SUSCEPTIBILITY TO CHRONIC DISEASEIssa Al Salmi Unknown Date (has links)
The thesis examines the relationship of birthweight to risk factors and markers, such as proteinuria and glomerular filtration rate, for chronic disease in postnatal life. It made use of the Australian Diabetes, Obesity and Lifestyle Study (AusDiab). The AusDiab study is a cross sectional study where baseline data on 11,247 participants were collected in 1999-2000. Participants were recruited from a stratified sample of Australians aged ≥ 25 years, residing in 42 randomly selected urban and non-urban areas (Census Collector Districts) of the six states of Australia and the Northern Territory. The AusDiab study collected an enormous amount of clinical and laboratory data. During the 2004-05 follow-up AusDiab survey, questions about birthweight were included. Participants were asked to state their birthweight, the likely accuracy of the stated birthweight and the source of their stated birthweight. Four hundred and twelve chronic kidney disease (CKD) patients were approached, and 339 agreed to participate in the study. The patients completed the same questionnaire. Medical records were reviewed to check the diagnoses, causes of kidney trouble and SCr levels. Two control subjects, matched for gender and age, were selected for each CKD patient from participants in the AusDiab study who reported their birthweight. Among 7,157 AusDiab participants who responded to the questionnaire, 4,502 reported their birthweights, with a mean (standard deviation) of 3.4 (0.7) kg. The benefit and disadvantages of these data are discussed in chapter three. The data were analysed for the relationship between birthweight and adult body size and composition, disorders of glucose regulation, blood pressure, lipid abnormalities, cardiovascular diseases and glomerular filtration rate. Low birthweight was associated with smaller body build and lower lean mass and total body water in both females and males. In addition low birthweight was associated with central obesity and higher body fat percentage in females, even after taking into account current physical activity and socioeconomic status. Fasting plasma glucose, post load glucose and glycosylated haemoglobin were strongly and inversely correlated with birthweight. In those with low birthweight (< 2.5 kg), the risks for having impaired fasting glucose, impaired glucose tolerance, diabetes and all abnormalities combined were increased by 1.75, 2.22, 2.76 and 2.28 for females and by 1.40, 1.32, 1.98 and 1.49 for males compared to those with normal birthweight (≥ 2.5 kg), respectively. Low birthweight individuals were at higher risk for having high blood pressure ≥ 140/90 mmHg and ≥ 130/85 mmHg compared to those with normal birthweight. People with low birthweight showed a trend towards increased risk for high cholesterol (≥ 5.5 mmol/l) compared to those of normal birthweight. Females with low birthweight had increased risk for high low density lipoprotein cholesterol (≥ 3.5 mmol/l) and triglyceride levels (≥ 1.7 mmol/l) when compared to those with normal birthweight. Males with low birthweight exhibited increased risk for low levels of high density lipoprotein cholesterol (<0.9 mmol/l) than those with normal birthweight. Females with low birthweight were at least 1.39, 1.40, 2.30 and 1.47 times more likely to have angina, coronary artery disease, stroke and overall cardiovascular diseases respectively, compared to those ≥ 2.5 kg. Similarly, males with low birthweight were 1.76, 1.48, 3.34 and 1.70 times more likely to have angina, coronary artery disease, stroke and overall cardiovascular diseases compared to those ≥ 2.5 kg, respectively. The estimated glomerular filtration rate was strongly and positively associated with birthweight, with a predicted increase of 2.6 ml/min (CI 2.1, 3.2) and 3.8 (3.0, 4.5) for each kg of birthweight for females and males, respectively. The odd ratio (95% confidence interval) for low glomerular filtration rate (<61.0 ml/min for female and < 87.4 male) in people of low birthweight compared with those of normal birthweight was 2.04 (1.45, 2.88) for female and 3.4 (2.11, 5.36) for male. One hundred and eighty-nineCKD patients reported their birthweight; 106 were male. Their age was 60.3(15) years. Their birthweight was 3.27 (0.62) kg, vs 3.46 (0.6) kg for their AusDiab controls, p<0.001 and the proportions with birthweight<2.5 kg were 12.17% and 4.44%, p<0.001. Among CKD patients, 22.8%, 21.7%, 18% and 37.6% were in CKD stages 2, 3, 4 and 5 respectively. Birthweights by CKD stage and their AusDiab controls were as follows: 3.38 (0.52) vs 3.49 (0.52), p=0.251 for CKD2; 3.28 (0.54) vs 3.44 (0.54), p=0.121 for CKD3; 3.19 (0.72) vs 3.43 (0.56), p= 0.112 for CKD4 and 3.09 (0.65) vs 3.47 (0.67), p<0.001 for CKD5. The results demonstrate that in an affluent Western country with a good adult health profile, low birthweight people were predisposed to higher rates of glycaemic dysregulation, high blood pressure, dyslipidaemia, cardiovascular diseases and lower glomerular filtration rate in adult life. In all instances it would be prudent to adopt policies of intensified whole of life surveillance of lower birthweight people, anticipating this risk. The general public awareness of the effect of low birthweight on development of chronic diseases in later life is of vital importance. The general public, in addition to the awareness of people in medical practice of the role of low birthweight, will lead to a better management of this group of our population that is increasingly surviving into adulthood.
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| 140 |
BIRTHWEIGHT AND SUSCEPTIBILITY TO CHRONIC DISEASEIssa Al Salmi Unknown Date (has links)
The thesis examines the relationship of birthweight to risk factors and markers, such as proteinuria and glomerular filtration rate, for chronic disease in postnatal life. It made use of the Australian Diabetes, Obesity and Lifestyle Study (AusDiab). The AusDiab study is a cross sectional study where baseline data on 11,247 participants were collected in 1999-2000. Participants were recruited from a stratified sample of Australians aged ≥ 25 years, residing in 42 randomly selected urban and non-urban areas (Census Collector Districts) of the six states of Australia and the Northern Territory. The AusDiab study collected an enormous amount of clinical and laboratory data. During the 2004-05 follow-up AusDiab survey, questions about birthweight were included. Participants were asked to state their birthweight, the likely accuracy of the stated birthweight and the source of their stated birthweight. Four hundred and twelve chronic kidney disease (CKD) patients were approached, and 339 agreed to participate in the study. The patients completed the same questionnaire. Medical records were reviewed to check the diagnoses, causes of kidney trouble and SCr levels. Two control subjects, matched for gender and age, were selected for each CKD patient from participants in the AusDiab study who reported their birthweight. Among 7,157 AusDiab participants who responded to the questionnaire, 4,502 reported their birthweights, with a mean (standard deviation) of 3.4 (0.7) kg. The benefit and disadvantages of these data are discussed in chapter three. The data were analysed for the relationship between birthweight and adult body size and composition, disorders of glucose regulation, blood pressure, lipid abnormalities, cardiovascular diseases and glomerular filtration rate. Low birthweight was associated with smaller body build and lower lean mass and total body water in both females and males. In addition low birthweight was associated with central obesity and higher body fat percentage in females, even after taking into account current physical activity and socioeconomic status. Fasting plasma glucose, post load glucose and glycosylated haemoglobin were strongly and inversely correlated with birthweight. In those with low birthweight (< 2.5 kg), the risks for having impaired fasting glucose, impaired glucose tolerance, diabetes and all abnormalities combined were increased by 1.75, 2.22, 2.76 and 2.28 for females and by 1.40, 1.32, 1.98 and 1.49 for males compared to those with normal birthweight (≥ 2.5 kg), respectively. Low birthweight individuals were at higher risk for having high blood pressure ≥ 140/90 mmHg and ≥ 130/85 mmHg compared to those with normal birthweight. People with low birthweight showed a trend towards increased risk for high cholesterol (≥ 5.5 mmol/l) compared to those of normal birthweight. Females with low birthweight had increased risk for high low density lipoprotein cholesterol (≥ 3.5 mmol/l) and triglyceride levels (≥ 1.7 mmol/l) when compared to those with normal birthweight. Males with low birthweight exhibited increased risk for low levels of high density lipoprotein cholesterol (<0.9 mmol/l) than those with normal birthweight. Females with low birthweight were at least 1.39, 1.40, 2.30 and 1.47 times more likely to have angina, coronary artery disease, stroke and overall cardiovascular diseases respectively, compared to those ≥ 2.5 kg. Similarly, males with low birthweight were 1.76, 1.48, 3.34 and 1.70 times more likely to have angina, coronary artery disease, stroke and overall cardiovascular diseases compared to those ≥ 2.5 kg, respectively. The estimated glomerular filtration rate was strongly and positively associated with birthweight, with a predicted increase of 2.6 ml/min (CI 2.1, 3.2) and 3.8 (3.0, 4.5) for each kg of birthweight for females and males, respectively. The odd ratio (95% confidence interval) for low glomerular filtration rate (<61.0 ml/min for female and < 87.4 male) in people of low birthweight compared with those of normal birthweight was 2.04 (1.45, 2.88) for female and 3.4 (2.11, 5.36) for male. One hundred and eighty-nineCKD patients reported their birthweight; 106 were male. Their age was 60.3(15) years. Their birthweight was 3.27 (0.62) kg, vs 3.46 (0.6) kg for their AusDiab controls, p<0.001 and the proportions with birthweight<2.5 kg were 12.17% and 4.44%, p<0.001. Among CKD patients, 22.8%, 21.7%, 18% and 37.6% were in CKD stages 2, 3, 4 and 5 respectively. Birthweights by CKD stage and their AusDiab controls were as follows: 3.38 (0.52) vs 3.49 (0.52), p=0.251 for CKD2; 3.28 (0.54) vs 3.44 (0.54), p=0.121 for CKD3; 3.19 (0.72) vs 3.43 (0.56), p= 0.112 for CKD4 and 3.09 (0.65) vs 3.47 (0.67), p<0.001 for CKD5. The results demonstrate that in an affluent Western country with a good adult health profile, low birthweight people were predisposed to higher rates of glycaemic dysregulation, high blood pressure, dyslipidaemia, cardiovascular diseases and lower glomerular filtration rate in adult life. In all instances it would be prudent to adopt policies of intensified whole of life surveillance of lower birthweight people, anticipating this risk. The general public awareness of the effect of low birthweight on development of chronic diseases in later life is of vital importance. The general public, in addition to the awareness of people in medical practice of the role of low birthweight, will lead to a better management of this group of our population that is increasingly surviving into adulthood.
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