In this thesis, we design novel implantable antennas for medical implant communication systems and it could operate with the metamaterial which is the artificial electromagnetic (EM) cover layer. The metamaterial based matching layer placed on the surface of the body can improve the performance of the implantable antenna. First, we propose two layers and three layers antenna design. The three layers antenna features high tolerance, high gain, low-profile and miniaturization. The antenna achieves gain −21.7 dBi and efficiency 0.2%. Compared with other literatures of implanted antenna design, the proposed three layers antenna reveals the best gain with similar dimensions. Furthermore, its frequency response is insensitive to the change of the implanted environment. The conception of impedance matching is applied to further improve the gain of the proposed antenna. The matching layers are realized by utilizing the metamaterial and it is placed between the body and the air. In this case, the gain of the three¡Vlayer antenna can be enhanced by 1.23¡V5.2 dB. Furthermore, we propose a size reduction technique to reduce the thickness of the matching layer. The miniature matching layers can increase the gain of the three¡Vlayer antenna by 1.64 dB and 2.63 dB with the dimension of 40¡Ñ40¡Ñ4mm³ and 60¡Ñ60¡Ñ4mm³ respectively. Finally, we propose a co¡Vdesign method of the antenna and metamaterial. The antenna will resonate after placing metamaterial on the surface of the body. So that we can control the antenna whether to transmit power or not by the circuit design in the biomedical device to detect the return loss of the antenna.

The objective of the proposed research is to advance the power efficiency of wireless neural stimulating systems in inductively powered implantable medical devices (IMD). Several innovative system- and circuit-level techniques are proposed towards the development of power-management circuits and wireless neural stimulating systems with inductive power transmission to improve the overall stimulation power efficiency. Neural stimulating IMDs have been proven as effective therapies to alleviate neurological diseases, while requiring high power and performance for more efficacious treatments. Therefore, power-management circuits and neural stimulators in IMDs should have high power efficiencies to operate with smaller received power from a larger distance. Neural stimulating systems are also required to have high stimulation efficacy for activating the target tissue with a minimum amount of energy, while ensuring charge-balanced stimulation. These features provide several advantages such as a long battery life in an external power transmitter, extended-range inductive power transfer, efficacious and safe stimulation, and less tissue damage from overheating. The proposed research presents several approaches to design and implement the power-efficient wireless neural stimulating IMDs: 1) optimized power-management circuits for inductively powered biomedical microsystems, 2) a power-efficient neural stimulating system with adaptive supply control, and 3) a wireless switched-capacitor stimulation (SCS) system, which is a combination structure of the power-management circuits and neural stimulator, to maximize both stimulator efficiency (before electrodes) and stimulus efficacy (after electrodes).

Le "gold-standard" du traitement chirurgical des scolioses est l'arthrodèse, qui consiste, à l'aide d'une instrumentation adaptée, à corriger et redresser les déformations scoliotiques, puis fusionner les vertèbres du segment pathologique afin de consolider la correction réalisée. Cette fusion entraine la destruction de la biomécanique physiologique du rachis, en supprimant sa mobilité et sa croissance. Les travaux réalisés dans le cadre de cette thèse portent sur le développement et la validation d'un nouveau concept d'instrumentation rachidienne ayant pour objectifs de réduire voire d'arrêter l'évolution des déformations rachidiennes, en conservant croissance et mobilité. Ce nouveau dispositif a nécessité une étude biomécanique large, partant du concept nouveau de cet implant, passant par la mise au point d'une méthodologie expérimentale, la conception et la réalisation de prototypes, puis leur validation à travers des études numériques, mécaniques, tribologiques et in vivo sur gros animal. La caractérisation in vitro du dispositif porte sur des essais mécaniques de caractérisation de matériau et des essais tribologiques de caractérisation du frottement. La caractérisation in vivo consiste en deux études menées sur gros animal, le modèle de porc Landrace, une première sur l'étude de l'arrachement de vis pédiculaires, puis une seconde, de validation de concept, avec 2 mois d'implantation du montage. Les premières conclusions tirées de ces travaux sont positives quant au bon fonctionnement du système. Des études en cours et à venir permettront de compléter ces résultats, et de valider le système dans son ensemble, afin de permettre sa future mise sur le marché. / The "gold standard" of surgical treatment of scoliosis is arthrodesis, which, with an appropriate instrumentation, corrects and straightens the deformities and fuses the vertebra of the pathologic segment to consolidate the correction. This fusion leads to the destruction of the physiological biomechanics of the spine, destroying growth and mobility. The work done in this thesis focuses on the development and validation of a new concept of spinal instrumentation which objectives are to reduce or even stop the development of spinal deformities, maintaining growth and mobility. This device is composed of materials used in new ways, leading to friction issues that do not exist in the current spinal systems. Thus, the system required a large biomechanical study, starting from the new concept of this implant, carrying on the development of an experimental methodology, designing and prototyping and then validation through numerical, mechanical, tribological and large animal in vivo studies. In vitro characterization of the device involves characterization of material through mechanical tests, and characterization of the tribological behavior of the system. In vivo characterization consists of two studies on large animal, the Landrace pig model : a first one on pedicle screws pullout, and a second one with 2 months of implantation, to validate the concept. The initial findings from this work are positive about the correct behavior of this system. Ongoing and future studies will complement those results, and validate the system as a whole, to allow future marketing.

<p>The rapid expansion of consumer Internet-of-Things (IoT) technology across various application domains has made it one of the most sought-after and swiftly evolving technologies. IoT devices offer numerous benefits, such as enhanced security, convenience, and cost reduction. However, as these devices need access to sensitive aspects of human life to function effectively, their abuse can lead to significant financial, psychological, and physical harm. While previous studies have examined the vulnerabilities of IoT devices, insufficient research has delved into the impact and mitigation of threats to users' privacy and safety. This dissertation addresses the challenge of protecting user safety and privacy against threats posed by IoT device vulnerabilities. We first introduce a novel IWMD architecture, which serves as the last line of defense against unsafe operations of Implantable and Wearable Medical Devices (IWMDs). We demonstrate the architecture's effectiveness through a prototype artificial pancreas. Subsequent chapters emphasize the safety and privacy of smart home device users. First, we propose a unique device activity-based categorization and learning approach for network traffic analysis. Utilizing this technology, we present a new smart home security framework and a device type identification mechanism to enhance transparency and access control in smart home device communication. Lastly, we propose a novel traffic shaping technique that hinders adversaries from discerning user activities through traffic analysis. Experiments conducted on commercially available IoT devices confirm that our solutions effectively address these issues with minimal overhead.</p>