Submitted by Ricardo Cedraz Duque Moliterno (ricardo.moliterno@uefs.br) on 2016-08-26T22:14:05Z No. of bitstreams: 1 Dissertacao_AGENILDA.pdf: 3220870 bytes, checksum: 32027f55b213f714258720168ab03b1c (MD5) / Made available in DSpace on 2016-08-26T22:14:05Z (GMT). No. of bitstreams: 1 Dissertacao_AGENILDA.pdf: 3220870 bytes, checksum: 32027f55b213f714258720168ab03b1c (MD5) Previous issue date: 2015-09-11 / Funda??o de Amparo ? Pesquisa do Estado da Bahia - FAPEB / This paper presents a study on the ways noted by the Indirect Anaphoras ( Marcuschi , 2005) in verbal- visual texts that enrich the possibilities for ( re) construction of the senses through elements of verbal and visual language . In light of this, this study will be from the theoretical perspective of Linguistics Textual, a social cognitive - interactional approach. The corpus consists of a selection of the genre strips, which has as main character a little boy named Calvin, name entitles these narratives created by American cartoonist Bill Watterson, exposed in the "Current" the New School Magazine and on the official site on the internet. About the indirect anaphoric relations, it can be said that there is a direct relationship between the antecedent (anchor) and the anaphoric term, which is introducing a new referent and the anaphoric relationship depends on an interpretation based on a calculation of inferential nature. Thus, it is considered that only the relations of lexical-semantic nature are not sufficient to explain the anaphoric relations and argues that these settings also depend on contextual and conceptual factors that allow the organized distribution of discourse objects, fulfilling a role important in textual progression. The results reinforce the relations established through the indirect anaphora and their anchors are not linked to the notion of correference and even it isn?t having this direct relationship, anchored in the textual universe, extrapolating the co-text and mobilizing a wide universe of cognitive strategies inherent in sociocultural interaction of the individual. The introduction of a new element in the text, even it not directly related to an antecedent, enables thematic continuity ensuring the textual progression. / RESUMO Neste trabalho, apresenta-se um estudo sobre os modos de referir por meio das An?foras Indiretas (MARCUSCHI, 2005) em textos verbo-visuais, que enriquecem as possibilidades de (re)constru??o dos sentidos atrav?s de elementos da linguagem verbal e da linguagem visual. Tendo isso em vista, esse estudo ser? feito sob a perspectiva te?rica da Lingu?stica Textual, numa abordagem sociocognitivo-interacional. O corpus constitui-se de uma sele??o do g?nero tirinhas, que traz como personagem principal um garotinho chamado Calvin, nome que intitula essas narrativas criadas pelo cartunista americano Bill Watterson, expostas na se??o ?Em dia? da Revista Nova Escola e na p?gina oficial da revista na internet. Sobre as rela??es anaf?ricas indiretas, pode-se dizer que n?o h? uma rela??o direta entre o antecedente (?ncora) e o termo anaf?rico, que h? introdu??o de um novo referente e que a rela??o anaf?rica depende de uma interpreta??o baseada num c?lculo de natureza inferencial. Dessa forma, considera-se que apenas as rela??es de natureza l?xico-sem?nticas n?o sejam suficientes para explicar as rela??es anaf?ricas e defende-se que essas configura??es dependem tamb?m de fatores contextuais e conceituais que permitir?o a distribui??o organizada de objetos de discurso, cumprindo um papel importante na progress?o textual. Os resultados refor?am que as rela??es estabelecidas atrav?s das an?foras indiretas e suas ?ncoras n?o est?o ligadas ? no??o de correferencialidade e, mesmo n?o tendo essa rela??o direta, ancoram-se no universo textual, extrapolando o cotexto e mobilizando um amplo universo de estrat?gias cognitivas inerentes ? intera??o sociocultural do indiv?duo. A introdu??o de um elemento novo no texto, mesmo sem rela??o direta com um antecedente, possibilita a continuidade tem?tica garantindo a progress?o textual.

Plusieurs études ont montré que certaines kinases situées dans le foie, « mammalian target of rapamycin » (mTOR), « adenosine monophosphate-activated protein kinase » (AMPK) et « general control non-depressible kinase 2 » (GCN2) répondent à la disponibilité en acides aminés.L’objectif de nos études a été de préciser le rôle de deux de ces voies, l’AMPK et GCN2, dans les adaptations du métabolisme énergétique et de la synthèse protéique en réponse aux variations en protéines du régime. Pour cela, des souris de type sauvage et des souris KO n’exprimant plus la voie AMPK ou GCN2 dans le foie ont été nourries pendant trois semaines avec un régime faible, normal ou fort en protéines. Les analyses ont montré que les souris KO-AMPK foie spécifique et nourries sous régime normoprotéique adaptent leur métabolisme hépatique notamment en sécrétant le facteur fibroblastique FGF21 ce qui leur permet de compenser l’absence d’AMPK et de présenter des profils d’oxydation normaux.Au contraire, les souris KO-AMPK foie spécifique nourries avec des régimes faibles ou forts en protéines présentent des altérations des profils d’oxydation des lipides et des glucides liées à une absence de modification du métabolisme hépatique.La délétion de GCN2 dans le foie, quant à elle, n’a d’effet que sous régime faible en protéines : les souris KO-GCN2 foie spécifique présentent une plus faible oxydation lipidique et une plus forte oxydation glucidique que les souris sauvages en période postprandiale dû à l’absence d’induction de la sécrétion de FGF21.Concernant le métabolisme des protéines, les kinases GCN2 et AMPK ne semblent pas impliquées dans l’intensité du flux de synthèse protéique dans le foie et en périphérie dans le muscle en période postprandiale.En conclusion, ces travaux montrent que les délétions de l’AMPK et de GCN2 hépatiques affectent le métabolisme énergétique mais pas le métabolisme protéique et que les conséquences dépendent de la composition du régime. / Several studies have reported that some kinases located in the liver respond to the availability of amino acids. These kinases are mammalian target of rapamycin '(mTOR), "adenosine monophosphate-activated protein kinase" (AMPK) and "general control non-depressible kinase 2" (GCN2).The aim of our study was to clarify the role of two of these signaling pathways, AMPK and GCN2 in the adaptations of energy and protein metabolism in response to the modulation of dietary protein content. Wild-type and liver AMPK-deficient or liver GCN2-deficient mice were fed either a low, a normal or high protein diet during three weeks. Analyzes showed that liver AMPK-deficient mice fed under a normo-protein diet exhibit an adapatation of liver metabolism and secret FGF21 which enables them to have normal postprandial oxidation profiles.In contrast, liver AMPK-deficient mice fed a low or a high protein diet exhibit an alteration in postprandial oxidation profiles. The deletion of GCN2 in the liver only has an effect under low protein diet as liver GCN2 deficient mice have a lower lipid oxidation and a higher carbohydrate oxidation linked to the absence of FGF21 secretion. Concerning protein metabolism, AMPK and GCN2 do not seem to be involved in protein synthesis rate in the posrprandial period in the liver and periphery in the postprandial muscle. In conclusion, these studies show that hepatic AMPK and GCN2 deletions affect energy metabolism, but not protein metabolism and that the consequences depend on diet composition.

Primäres Ziel von ICAP (internationaler Konsens für antinukleäre Antikörpermuster) ist es, einen Konsens zu finden zur Beschreibung der Fluoreszenzmuster, die mit indirekter Immunfluoreszenztechnik auf HEp-2-Zellen erkannt werden können. 28 Muster (14 Kern-, 9 zytoplasmatische und 5 mitotische Muster) wurden bisher definiert. Neben der Musterbeschreibung wurden alle Muster auch mit AC-Nummern gekennzeichnet, um eine von der Sprache unabhängige Vergleichbarkeit zu gewährleisten. Alle ICAP-Ergebnisse können von der ICAP-Internetseite (www.anapatterns.org) abgerufen werden. ICAP ist ein fortlaufender Prozess. Das nächste und 4. ICAP-Treffen wird im September 2017 im Rahmen des 13. Autoantikörpersymposiums in Dresden stattfinden (www.gfid-ev.de). Anstehende ICAP-Aufgaben sind die Ergänzung der Fluoreszenzmuster, die Erweiterung der Bildersammlung und die genauere Beschreibung der klinischen Bedeutung einzelner Muster.

The diploma thesis focuses on voluntary tools that the business entities by using them can try to reduce the negative impact on the environment which may arise in connection with their activities. Attention is paid on the Eco Management and Audit Scheme (EMAS) on the basis of which environmental review and identification of indirect environmental aspects of the selected company is carried out. The result is proposed measures on indirect environmental aspects and an assessment of the appropriateness of the introduction of EMAS into the practice of the company Technické služby Jeseník.

The diploma thesis deals with the state of the real estate market with the residential units in new buildings of the apartment buildings in Chrudim. The target of the thesis is to determine the influence on the price of residential units of the given locality and how the influence of prices on the other factors and to evaluate the influence of the location on a larger scale, by comparing the prices of residential units in new buildings in different cities. The theoretical part of the diploma thesis is focused on the topic of valuation. Practical then by describing localities and their differences and comparing the prices of the residential units.

The objective of this study was the calculation and optimalization methods of the indirect spectrophotometric determination of fluoride based on the zirconium complex. Three organic reagent eriochromcyanin R chromazurl S and xylenol orange were tested. As the most sensitive system was shown the complex of zirconium with xylenol orange. Linear standard curve was ranged from 1,5.10-6 to 7,5.10-5 mol.dm-3. H2PO4-, Fe3+ and the highest concentrations of Fe2+, SO42- were tested for interferent. The Fe2+ and SO4- interfere only above the concentration which cannot be found in natural water. The optimized method was applied for the determination of fluoride in the model and real drinking, mineral and surface water.

In the introductory chapter of this work is caught organizational structure of the national metrology system in the Czech Republic and its links to international organizations. There is indicated the basic terminology of metrology, particularly in the area of classification instruments. The following sections approaching the issue of measurement uncertainties, their classification, sources of uncertainty determined by the type A and B, their specifics and calculation. The above linked area already dealing with themselves calibrations, first of all calibration weights, classification of weights according accuracy classes, established procedures, and finally determining uncertainty in calibration weights. Then, immediately followed by a chapter dealing with calibration balances, performed tests and measurement uncertainties. The main part is of course directed towards the application of acquired knowledge to practical examples, thus performing the calibration weight class F2 using a high-precision weights, both in the premises of the Technical University in Brno, both in the laboratory weighing the Czech Metrological Institute. Further calibration was performed school balances Ohaus Explorer EX224.

The diploma thesis „Indirect Tax Harmonization in the European Union“ deals with the indirect tax harmonization issues, which are related to accession the Czech Republic to the EU. It analyzes changes in harmonization with the focus on value added tax and its impact on businesses. The aim of this thesis is on a sample of respondents using a questionnaire to find out how the businesses look at this problem, which the harmonization of indirect taxes directly concerned.

The thesis is focused on issues of effective cost control. It, in detail, discusses the structure and dividing of costs and introduces the main instrument of cost control - calculations. The first part of the thesis covers theoretical findings concerning the given issue. The second part is comprised of cost control analysis in a particular manufacturing company. In conclusion, the present method of cost calculation in use is evaluated and the new method is proposed.

The interior light with the changable color temperature, which can react to various daytime and also react to requirements of the customer. This feature is possible by LED technology. The shape of the light comes from undersea inspiration. The light wants to remain to the man his natural environment. And also respect his lighting needs. The light would be made from the segments which are possible to adapt in any interior by size. And also with more segments we can get more light intensity.