L’objectif de cette thèse est d’établir et comprendre le cycle biogéochimique du bore et de ses isotopes au sein d’un écosystème forestier. Dans ce contexte, beaucoup de questions subsistent à propos du cycle biogéochimique du bore dans les écosystèmes terrestres, à savoir : • Quelles sont les sources majeures de bore dans les écosystèmes forestiers ? • Quelles sont les types de transfert entre les différents compartiments de l’environnement ? • Quels mécanismes contrôlent ces échanges ? Pour établir ce cycle, nous allons quantifier les différents stocks (végétation, sol) et flux (apports atmosphériques dissous et particulaires, pluviolessivats, ruissellements de tronc, litières, profils de sol et drainage) de bore dans le site atelier de l’OPE situé dans la forêt domaniale de Montiers-Sur-Saulx (Meuse). Il est important de noter que nous utiliserons les isotopes du bore (11B et 10B) afin de comprendre la dynamique de son cycle biogéochimique ainsi que les échelles de temps des échanges ayant lieu entre les différents compartiments environnementaux. Au final, cette thèse se divise en quatre parties distinctes : 1. Une première partie de développement analytique, visant à la mise en place, l’extraction, la purification et la mesure du bore et de ses isotopes au sein des matrices végétales. 2. Une seconde partie focalisée sur les origines et mécanismes qui contrôlent les apports atmosphériques dissous et particulaires sur le site atelier de Montiers. 3. La troisième partie vise à établir les différents transferts de bore dans le système sol plante sur deux sols distincts : un rendisol, basique ainsi qu’un alocrisol, acide. Le but de cette démarche est d’évaluer dans un premier temps l’influence des composantes du cycle biogéochimique sur les transferts de bore puis, dans un second temps, d’évaluer l’influence des propriétés d’un sol sur la dynamique du cycle biogéochimique d’un écosystème. 4. La dernière partie vise à établir un modèle d'évolution du bore et de ses isotopes dans le système sol-plante. Ce modèle est principalement basé sur les observations réalisées durant l'année 2012 / This thesis aims at establishing and understanding the biogeochemical cycle of boron and its isotopes within a forest ecosystem. In that context, many questions remain concerning the dynamics of boron within terrestrial ecosystems: • What are the major sources of boron? • What type of transfer occurs between the compartments of the environment? • What mechanisms are controlling those transfers? In order to establish this biogeochemical cycle, we quantified the different stocks (vegetation, humus and soil) and fluxes (atmospheric dust and dissolved deposition, throughfalls, stemfloxs, litterfall and drainage) of boron in the study site of Montiers. The use of boron isotopes will give us insight concerning the mechanisms controlling the dynamics of boron. This thesis is divided in 4 main parts: 1. The first part aims at establishing a new method of extraction, purification and measurement of boron and its isotopes within vegetation samples. 2. The second part focuses on the sources and mechanisms controlling boron within atmospheric dust and dissolved deposition on the study site of Montiers. 3. The third part aims at establishing the stocks and fluxes of boron on two distinct soils: a rendisoil (basic pH) and an alocrisoil (acid pH). The goal is to determine the influence of different soil properties on boron dynamics within its biogeochemical cycle. 4. The last part aims at establishing a model of boron and boron isotopes dynamics in the soil plant system. This model is mainly based of the measurement made in 2012

Submitted by Biblioteca da Faculdade de Farmácia (bff@ndc.uff.br) on 2018-03-21T16:48:24Z No. of bitstreams: 1 STEFÂNIA LEIRIAS BRAGA.pdf: 3310134 bytes, checksum: 22a41b63f66c87e21d2e37e21ea7c0ac (MD5) / Made available in DSpace on 2018-03-21T16:48:24Z (GMT). No. of bitstreams: 1 STEFÂNIA LEIRIAS BRAGA.pdf: 3310134 bytes, checksum: 22a41b63f66c87e21d2e37e21ea7c0ac (MD5) Previous issue date: 2017 / Nas últimas décadas a produção nacional de medicamentos a partir de insumos fabricados nacionalmente tem sido estimulada através de vários programas de governo, por entender que os medicamentos são um produto estratégico, tratado em políticas públicas que envolvem a melhoria da saúde da população brasileira. Esse trabalho teve por objetivo, observar se após a adoção do programa de Parceria de Desenvolvimentos Produtivo, entre empresas públicas e privadas, houve alguma mudança na importação dos insumos farmacêuticos ativos: clozapina, cabergolina e lamivudina durante o período de 2010 a 2015. Foram coletados dados dos insumos importados e observados se os mesmos atendiam às normas regulatórias sanitária vigentes, assim como os dados epidemiológicos de doenças tratadas por estes medicamentos e seus hábitos de prescrição médica. Os resultados iniciais revelaram que houve uma diminuição de 50% na quantidade da importação do IFA Cabergolina, a cada ano, a partir do ano de 2013, também foi observado, uma estabilização, sem aumento do quantitativo importado, do IFA Clozapina e em estudos complementares mostrou a diminuição da importação do IFA Lamivudina. A queda no número das importações, não estava relacionada a uma possível diminuição no número de casos das doenças, ou a alguma mudança no hábito de prescrição dos medicamentos contendo os IFA importados. Durante o desenvolvimento do estudo foi observado um aumento das adequações sanitária, e do cumprimento das normas regulatórias a publicações das mesmas pela Anvisa / In the last decades, the national production of drugs from nationally manufactured inputs has been stimulated through several government programs, because they understand that medicines are a strategic product, treated in public policies that involve improving the health of the Brazilian population. The objective of this study was to observe whether there was any change in the importation of the active pharmaceutical inputs: clozapine, cabergoline and lamivudine during the period from 2010 to 2015 after the adoption of the Productive Development Partnership program between public and private companies. Data on imported inputs and observed whether they met the current sanitary regulations, as well as epidemiological data on the diseases treated by these medicines and their medical prescription habits. The initial results showed that there was a decrease in the amount of 50% of the import of IFA Cabergoline, every year, from 2013 onwards, a stabilization was also observed, with no increase in the imported quantity, of IFA Clozapine and in studies showed a decrease in the importation of IFA Lamivudine. The decrease in the number of imports was not related to a possible decrease in the number of cases of the diseases, or to some change in the prescription habits of the medicines containing the imported IFAs. During the development of the study it was observed an increase in the sanitary adequacy, and of the compliance with the regulatory norms to the publications of the same ones by Anvisa

Dissertação(mestrado) - Universidade Federal do Rio Grande, Programa de Pós-Graduação em Oceanografia Física, Química e Geológica, Instituto de Oceanografia, 2007. / Submitted by Cristiane Silva (cristiane_gomides@hotmail.com) on 2013-02-18T17:26:18Z No. of bitstreams: 1 2007_karina_attisano.pdf: 8850374 bytes, checksum: 292caec84f69bf4efc38580f79e98729 (MD5) / Approved for entry into archive by Bruna Vieira(bruninha_vieira@ibest.com.br) on 2013-06-13T18:40:54Z (GMT) No. of bitstreams: 1 2007_karina_attisano.pdf: 8850374 bytes, checksum: 292caec84f69bf4efc38580f79e98729 (MD5) / Made available in DSpace on 2013-06-13T18:40:54Z (GMT). No. of bitstreams: 1 2007_karina_attisano.pdf: 8850374 bytes, checksum: 292caec84f69bf4efc38580f79e98729 (MD5) Previous issue date: 2007 / A costa sul do Brasil, constituída pelas áreas costeiras e oceânicas do Rio Grande do Sul e Santa Catarina, é conhecida como uma das regiões de maior potencial pesqueiro de todo o litoral brasileiro. Isto se deve, sobretudo, a presença de várias massas de água que interagem formando um sistema complexo, dinâmico e altamente produtivo. Além dos intensos processos de mistura, essas regiões apresentam frentes termohalinas e ação de ventos. O presente trabalho apresenta um diagnóstico comparativo, de enfoque químico, entre a plataforma das regiões de Santa Marta (SC) e Albardão (RS). Para tanto, são utilizados parâmetros hidroquímicos, amostrados em 33 estações oceanográficas importantes para a avaliação da produção biológica, e também a interpretação dos processos oceanográficos. Ao efetuar a comparação entre as referidas regiões de plataforma, durante o inverno de 2005, observou-se claramente maiores concentrações de nutrientes dissolvidos na região do Albardão, devido a menor influência da Água Tropical, apresentando-se submetida a processos oceanográficos mais intensos resultantes da proximidade à Convergência Subtropical, da intrusão da Água Subtropical de Plataforma (através do paleocanal), da formação da Frente Subtropical de Plataforma, frentes frias e do volume de descarga continental substancial proveniente do Rio do Prata, Lagoa dos Patos e do transporte subterrâneo que potencializam a dinâmica entre as massas de água, elevando a produtividade da região. / The southern Brazilian Coast comprises of the coastal and oceanic areas of Rio Grande do Sul and Santa Catarina and is a region with the highest fishing potential along the Brazilian coast. This is due to the presence of several water masses that interact form a complex, dynamic and highly productive system. Mixing is also provided by thermohaline fronts, upwelling and wind. The present work presents a diagnosis, using hydrochemical data, between Santa Marta Shelf (SC) and Albardão (RS) (33 oceanographic stations) to determine biological production and other oceanographical processes. During the 2005 winter there were higher nutrients concentrations in Albardão zone, due to less influence of Tropical Water. There is high productivity in the region due to mixing of water masses by proximity to Subtropical Convergence, intrusion of the Subtropical Water on to the Shelf (through the paleochannel), formation of Subtropical Shelf Front, groundwater transport, cold fronts discharge from Prata River, Patos Lagoon.

No description available.

Actualmente, la alimentación no balanceada es uno de los mayores problemas de nuestro país. La mayoría de las personas no cuenta con educación alimenticia para el cuidado de su dieta diaria. Por ello, el consumo desordenado de alimentos con altos índices de azúcar, sodio, preservantes, entre otros influye constantemente en el desarrollo de enfermedades como diabetes, anemia y demás. Asimismo, se puede evidenciar que el mercado no cuenta con alternativas saludables, que satisfagan a clientes que demandan productos golosinaros que no perjudiquen su salud (snacks). Por ello, se ha realizado un plan de negocios que evalúa, desarrolla y genera gomitas saludables a base de insumo naturales, denominado GOMIFRUT. Cabe resaltar que cuenta con 2 presentaciones: Frutos Tropicales y Frutos silvestres, los cuales son elaborados salubremente. Asimismo, el objetivo del proyecto es que las personas puedan integrar el producto a su dieta diaria teniendo la seguridad de que no serán perjudicados por su ingesta. En un plazo de 2 años y 6 meses aproximadamente, se demuestra una generación de valor por S/14,437 incluyendo la inversión realizada y todos los recursos necesarios para su óptimo funcionamiento. / Nowadays, unbalanced food is one of the biggest problems in our country. Most people do not have food education to take care of their daily diet. Therefore, the disordered consumption of foods with high levels of sugar, sodium, preservatives, among others, constantly influences the development of diseases such as diabetes, anemia and others. Likewise, it can be seen that the market does not have healthy alternatives that satisfy customers who demand sweet products that do not harm their health (snacks). For this reason, a business plan has been developed that evaluates, develops and generates healthy gummies based on natural ingredients, called GOMIFRUT. It is worth mentioning that it has 2 presentations: Tropical fruits and wild fruits, which are produced in a healthy way. Likewise, the objective of the project is that people can integrate the product to their daily diet having the security that they will not be harmed by its ingestion. In a period of 2 years and 6 months approximately, it is demonstrated a generation of value for S/14,437 including the investment made and all the necessary resources for its optimal operation. / Trabajo de investigación

En esta investigación se examina la creación de la idea de negocio llamada Doña Hermelinda. Esta idea surgió debido a la coyuntura actual en la que se encuentra el país, adaptando el producto a las necesidades actuales. La investigación nos ha permitido confirmar la viabilidad de nuestro proyecto incursionando nuestra marca en el mercado de Lima. Para ello hemos utilizado un canal de ventas principal es cual fue las redes sociales del proyecto, lo cual nos permitió obtener resultados satisfactorios expresados en las ventas realizadas. Luego de pasar por un proceso de validación de problema, de idea de negocio y concierge, se procedió a realizar los planes a futuro respectivos lo cual se concluyó en la realización del plan financiero. Los resultados de nuestra investigación se pueden resumir en que nuestro VAN es de 139,073 con un retorno en el año 3 y nuestro TIR es de 37.21% lo cual demuestra la viabilidad del proyecto. / This research examines the creation of the business idea called Doña Hermelinda. This idea arose due to the current situation in which the country finds itself, adapting the product to current needs. The research has allowed us to confirm the viability of our project by entering our brand in the Lima market. For this we have used a main sales channel which was the project's social networks, which obtained satisfactory results expressed in the sales made. After going through a process of validation of the problem, the business idea and the concierge, the selected future plans were carried out, which was concluded in the realization of the financial plan. The results of our research can be summarized in that our NPV is 139,073 with a return in year 3 and our IRR is 37.21% which shows the viability of the project. / Trabajo de investigación

Debido a los sucesos que contrajo la pandemia del Covid-19 en nuestro país, se incrementó la demanda de productos de limpieza de higiene como jabones y gel antibacteriales para generar protección ante un posible contagio de este virus. Según datos reportados el sector que tuvo un mayor incremento en ventas fue el de limpieza. Dentro de este sector se encuentra Paper Clean, el cual, es un proyecto de negocio que tiene como propósito brindar un producto de limpieza de manos, tal como son las láminas de jabón que tiene como características ser antibacterial, con insumos naturales, variedad de aromas, innovador, con calidad e higiénico. Asimismo, nuestros jabones en láminas estarán enfocados a Mujeres del sector A y B dentro de Lima moderna.  Este proyecto surge con la finalidad de poder brindar a nuestro público un producto de calidad, diferente y que tenga un valor agregado para poder diferenciarnos del resto del mercado y que a la vez le genere bienestar y seguridad a nuestro público al usar nuestro producto. Este proyecto expone un análisis de los retos que conlleva participar en un mercado altamente competitivo y que nos obliga a diferenciarnos de la competencia, como también cómo emplearemos nuestras estrategias de operación, publicidad y se mostrará que el proyecto es viable lo que debe ser avalado por nuestros análisis financieros. / Due to the events of the Covid-19 pandemic in our country, the demand for hygiene cleaning products such as antibacterial soaps and gel was increased to generate protection against possible contagion of this virus. According to reported data the sector that had the greatest increase in sales was the cleaning. Within this sector is Paper Clean, which is a business project that aims to provide a hand cleaning product, such as soap sheets, which has the characteristics of being antibacterial, with natural inputs, a variety of aromas, innovative, with quality and hygienic. In addition, our foil soaps will be focused on Women from sector B within modern Lima. This project arises in order to be able to provide our audience with a quality product, different and that has added value to be able to differentiate us from the rest of the market and that at the same time generates well-being and safety to our public when using our product. This project sets out an analysis of the challenges of participating in a highly competitive market that forces us to differentiate ourselves from competition, as well as how we will use our trading strategies, advertising and show that the project is viable which should be endorsed by our financial analyses. / Trabajo de investigación

Budget cuts at a California community college prompted stakeholders to consider dropping the college's general education information literacy (IL) requirement. Broad institutional outcomes data showed learning gains, but no targeted assessment existed regarding the IL requirement's impact on those gains. This quantitative study used Astin and Antonio's Inputs-Environment-Outcomes (I-E-O) assessment model to address relationships among student characteristics of demographic and prior preparation (Inputs), the IL requirement (Environment), and student reports of information critical analysis behavior and confidence (Outcomes). Study participants were 525 students aged 18 years and older who had completed the IL course with a grade of 2.0 or better and volunteered to complete an anonymous survey. The majority of participants reported the IL requirement had a positive impact upon subsequent coursework, with 87% stating that taking it in the first or second term would be most helpful. Less preparedness for information critical analysis prior to the IL course was significantly correlated (r = -.35, r = -.38, p < .001) with higher reported frequency of 2 measures of information evaluation changes following completion of the course. The 3 hierarchical multiple regression analyses revealed that the predictors of student demographic characteristics, prior student preparation, and IL course format contributed significantly to reported information critical analysis and confidence. The study's outcome was a white paper with recommendations to support completion of the IL course requirement early, continue the IL requirement, and repeat the study's survey in the future. Effective IL education promotes information evaluation behaviors essential to informed members of society.

Despite 25 years of concerted efforts by African governments to adopt consistent policies for increasing food production, hunger and poverty are still prevalent in the continent. Using Bernanke's conceptualization of the credit channel theory of monetary policy, the purpose of this correlational study was to investigate whether a subsidy program, the National Accelerated Agricultural Inputs Access Program (NAAIAP), affected the rates of fertilizer usage and food production in Kakamega County, Western Kenya. Purposive stratified sampling was used to select 114 participants consisting of 72 farmers in each of the 2 groups: NAAIAP beneficiaries and nonbeneficiaries. Participants completed a survey on fertilizer usage rates, income earned, and surplus maize yield. Data were analyzed using multiple regression to test whether there was a difference between the beneficiary and nonbeneficiary groups regarding income, surplus product, and the dependent variable of fertilizer usage. Results indicated that beneficiaries of NAAIAP credit program bought and prepared to use fertilizers significantly earlier than did their counterparts. Further, the results of multiple regression indicated significant positive correlation (p <.05) between income earned from sale of surplus maize yield and quantity of fertilizer used by farmers in Kakamega County. These findings suggest that NAAIAP improved food security and farmers' income in Kakamega Count. This study contributes to social change by recommending to subsidy program administrators in Kakamega County to consider policy changes. Such policy changes may improve program outreach to resource-poor farmers and improve income and product yield in the agricultural sector of Kenya.

No description available.