Dissertação (mestrado)—Universidade de Brasília, Instituto de Letras, Departamento de Teoria Literária e Literaturas, Programa de Pós-Graduação em Literatura, 2012 / Submitted by Albânia Cézar de Melo (albania@bce.unb.br) on 2013-01-23T15:21:29Z No. of bitstreams: 1 2012_MariaClaraDunckSantos.pdf: 1250114 bytes, checksum: c70afeb1a3da1650be18661c835f0eb8 (MD5) / Approved for entry into archive by Guimaraes Jacqueline(jacqueline.guimaraes@bce.unb.br) on 2013-01-24T11:42:46Z (GMT) No. of bitstreams: 1 2012_MariaClaraDunckSantos.pdf: 1250114 bytes, checksum: c70afeb1a3da1650be18661c835f0eb8 (MD5) / Made available in DSpace on 2013-01-24T11:42:46Z (GMT). No. of bitstreams: 1 2012_MariaClaraDunckSantos.pdf: 1250114 bytes, checksum: c70afeb1a3da1650be18661c835f0eb8 (MD5) / O advento da Segunda Guerra Mundial trouxe consigo grandes mudanças no cenário artístico global. Para a compreensão da literatura produzida nesse período, é necessário tratar da Contracultura, um movimento contestador que faz oposição à cultura dominante. Esta, de caráter conservador e elitista, serve à indústria cultural, como um importante veículo de propagação e manutenção do establishment. Apesar de apoiada por uma minoria, a Contracultura é fundamental para a compreensão da literatura contemporânea, visto que, ao se popularizar, contribuiu para a formação da dominante cultural do século XXI: a pós-modernidade. Este estudo compara duas literaturas contraculturais: uma norte-americana da década de 1950, conhecida como geração beat, e outra brasileira da década de 1970, chamada de geração mimeógrafo. Afirma-se que a brasileira é epígona da norte-americana. E para contrapor tal assertiva, esta pesquisa vale-se da Teoria dos Polissistemas, aliada à análise semiótica da poética de Jack Kerouac, no caso da geração beat, e da poética de Nicolas Behr, da geração mimeógrafo. ______________________________________________________________________________ ABSTRACT / The advent of Second World War brought relevant changes in the global art scene. For understanding the literature produced during this period, it is necessary to study the Counterculture, a movement that opposes to the dominant culture, which serves the Culture Industry as an important vehicle for the propagation and maintenance of the conservative and elitist establishment. Although the Counterculture is supported by a minority, it is fundamental to the understanding of contemporary literature because its posterior popularity contributed to the formation of the dominant culture of the twenty-first century: the postmodernity. This study compares two countercultural literatures: an American in the 1950s, known as the Beat Generation, and another, Brazilian, in the 1970s, called geração mimeógrafo. It is said that the Brazilian counterculture literature is an epigone to the U.S. To prove this assertion, this research uses the Theory Polysystem allied to a semiotic analysis of the poetry of Jack Kerouac, in the case of the Beat Generation, and the poetry of Nicolas Behr, of the geração mimeógrafo.

This thesis uses Jack Gilbert's Refusing Heaven to look critically at the evolution of American poetry.

No presente trabalho, o peptídeo inseticida recombinante Jaburetox-2Ec, derivado da urease de Canavalia ensiformis (Jack bean) foi estudado, principalmente através de técnicas de espectroscopia de espalhamento de luz e raios-X. Foi analisada a tendência do peptídeo a se agregar em diferentes condições físico-químicas quando em solução aquosa, e a sua interação com membranas de lipossomas miméticos de plaquetas humanas. A partir dos dados de raio hidrodinâmico, raio de giro, e massa molar ponderal média obtidos do peptídeo em solução, foi possível observar uma tendência para maior agregação numa faixa em torno de pH 5,5, bem como ausência de agregação em pH inferior a 4,0 e superior a 7,0. Não se verificou nenhum efeito visível no nível de agregação com a adição de agente redutor ou íons, sendo que a exposição ao oxigênio do ar levou a um aumento da mesma. Os estudos de interação do Jaburetox-2Ec com lipossomas revelaram uma significante mudança estrutural na membrana, que se mostrou mais intensa com uma maior concentração do peptídeo. Foram, através de software, feitos ajustes teóricos das curvas de espalhamento de raios-X à baixos ângulos dos lipossomas, a fim de quantificar as mudanças nos parâmetros físicos das membranas causados pela ação do peptídeo. A formação de poros na membrana pelo peptídeo foi proposta como explicação para os resultados encontrados. / In the present work, the insecticide recombinant peptide Jaburetox-2Ec, derived from Canavalia ensiformis (Jack bean) urease, was studied, primarily by light and X-ray scattering techniques. Its tendency to aggregate in aqueous solution under different physical-chemical conditions, and its interaction with human platelet mimetic liposome membranes were analyzed. From the data relative to hydrodynamic radii, radii of gyration and mean molecular weight obtained from the peptide in aqueous solution, it was possible to observe a tendency for greater aggregation around pH 5.5, as well as an absence of aggregation at values of pH below 4.0 and above 7.0. No visible effect on the level of aggregation was verified with the addition of reducing agent or ions, whereas the exposure to oxygen in the air resulted in an increase in this level. The studies of Jaburetox-2Ec interaction with liposomes revealed a significant structural change in the membrane, which was shown to be more intense in higher peptide concentrations. Software-assisted theoretical fits were made for the experimental small-angle X-ray scattering curves aiming to quantify the changes in the physical parameters of the membranes caused by peptide action. The formation of pores in the membrane was proposed as an explanation to the results found.

Made available in DSpace on 2014-06-12T18:04:23Z (GMT). No. of bitstreams: 2 arquivo7752_1.pdf: 2968182 bytes, checksum: b99b78d01729ac83718a680337a6d7f1 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2006 / Faculdade de Amparo à Ciência e Tecnologia do Estado de Pernambuco / Os resultados apresentados nesta tese podem ser divididos em duas partes. Na primeira estudamos uma classe de ensembles de movimento browniano (EMB) da teoria de matrizes aleatórias, gerados a partir da teoria matricial de processos estocásticos markovianos. Os ensembles são caracterizados por uma equação de Fokker-Planck e estão intimamente relacionados a hamiltonianos de sistemas quânticos do tipo Calogero-Sutherland. Esta conexão leva a um esquema geral de classificação baseada numa recente generalização multidimensional dos polinômios ortogonais clássicos. Mostramos que, sob certas condições, os EMB englobam os ensembles de matrizes de transferência. Desta forma, desenvolvemos um tratamento unificado dos ensembles de polinômios e de matrizes de transferência que, além de servir como um esquema de classificação das diversas classes de simetria, fornece técnicas eficientes de cálculo. Desenvolvemos métodos de Fokker-Planck para o cálculo de médias de observáveis representados por estatísticas lineares, assim como para o cálculo de funções de correlação. Neste contexto, desenvolvemos um método de transformada integral e uma generalização do método das funções biortogonais para o cálculo da função de correlação de n-pontos. Os resultados deduzidos neste contexto geral são aplicados a pontos e fios quânticos. Em particular, apresentamos um estudo numérico de propriedades de transporte em pontos quânticos com simetria quiral. Na segunda parte, estudamos uma cavidade caótica balística acoplada, via barreiras de transparência arbitrária, a dois guias semi-infinitos usando as duas abordagens de teoria de circuito disponíveis na literatura: a escalar e a matricial. Mostramos a equivalência destas teorias através do cálculo dos cumulantes da estatística de contagem. Para isso, determinamos as funções geratrizes fornecidas pelas duas teorias e verificamos a concordância dos 18 primeiros cumulantes usando um programa de computação algébrica. Também estudamos distribuições exatas de corrente de alguns sistemas simples de dois terminais, como um ponto quântico com barreiras simétricas. Estes resultados são importantes, pois fornecem uma grandeza diretamente mensurável em experimentos

Magister Scientiae (Medical Bioscience) - MSc(MBS) / Eurycoma Longfolia Jack, also known as Tongkat Ali (TA) is a tropical plant belonging to the family of Simaroubaceae is widely distributed in South East Asian countries. The extracts of TA have been proven to have cytotoxicity, anti-proliferative and aphrodisiac properties. In vitro assays revealed cytotoxicity toward human breast cancer cell lines MCF-7, KB, CaOV-3, RD, DU-145and HepG2 human liver cancer cells and appear promising as a new chemotherapeutic agent against human cervical carcinoma (HeLa) cells. Although, there are extensive studies reported on its cytotoxicity benefits there are none pertaining to LNCaP human prostate cell line. Therefore, this study aimed at testing the effects of TA on LNCaP cells and prostate specific antigen (PSA) production. Materials and Methods This study investigated the effect of different concentrations of TA (0.0025, 0.025, 2.5, 25 and 250 g/ml) TA on LNCaP human prostate cancer cell line for 24 and 96 hours. The following parameters were investigated: morphology, cell viability (MTT), testosterone modulation, Annexin V-CY3 binding (Apoptosis), DNA fragmentation (TUNEL), caspase 3/7 activity (apoptosis), and PSA production. Results When observing the morphological changes of LNCaP cells exposed to TA, a clear increase in detachment and cell death via apoptosis as the concentrations of TA increased. The viability decreased significantly in both 24 and 96 hour treatment of TA at higher dosages (25 and 250 g/ml). The significant inhibitory effects on testosterone stimulated cell proliferation were seen at TA concentrations as low as 0.0025 μg/ml TA. At higher concentrations of TA (25 and 250 μg/ml), for all testosterone dosages a decreasing trend in proliferation was found. vii Testosterone concentrations of 10 nM showed maximum stimulation of cell proliferation for TA dosages up to 2.5 μg/ml. All concentrations of TA showed significant increase in apoptosis of the cells as dosages increased. A higher amount of DNA damage found at the highest dosage (250 μg/ml) of TA. The relative caspase 3/7 activation showed significant (P=0.0043) activation at the highest concentration (250 μg/ml) of TA. Relative PSA production resulted only a 5% increase with no significant difference at all doses indicting that TA does not change the cell PSA production and the decline in PSA concentration is due to LNCaP cells dying as a result of this exposure to TA. Conclusion In summary, the major finding of this study is that Tongkat Ali inhibits the viability of prostate cancer cell lines (LNCaP) through caspase-mediated pathway, as well as increased the level of apoptotic such as DNA fragmentation. In addition, Tongkat Alin also inhibited PSA production. In LNCaP cells, testosterone with the addition of TA does not increase the growth of the cells. However, more in-vitro and in-vivo studies are needed to establish the exact constituents of the extracts and their mechanism of action. Thus, this study opens perspectives on the use of Tongkat Ali preparations in the treatment of aging male symptoms, prostate cancer prevention or as additional treatment to standard prostate cancer therapy.

Eddy-covariance (EC) CO₂ flux data were analysed and annual carbon (C) balances estimated for a four-year period (2004-2007) following clearcut harvesting of a boreal jack pine stand in northern Saskatchewan. The site was a source of C to the atmosphere for all years, with annual net ecosystem productivity (NEP) increasing from -153 g C m⁻² yr⁻¹ in 2004 to -63 g C m⁻² yr⁻¹ in 2007. This increase was mainly due to gross primary productivity (GPP) increasing significantly from 78 to 200 g C m⁻² yr⁻¹ , while ecosystem respiration (R) increased only slightly from 231 to 263 g C m⁻² yr⁻¹ over the same period. In the 2006 growing season (GS), a field campaign was conducted to investigate the relationships between monthly destructive measurements of leaf area index (LAI) and daily measurements of the normalized difference vegetation index (NDVI) and photosynthetic capacity (Amax). The latter was derived from 5-day, 16-day, 30-day and annual Michaelis-Menten light response analyses using daytime measurements of NEP and incident photosynthetically active radiation. Digital-camera data were used to evaluate the potential of using the rectilinear-lens vegetation index (RLVI) as a surrogate for NDVI of a young forest stand. Results showed that LAI was linearly related to NDVI and RLVI, which was largely the result of changes in the deciduous vegetation component across the GS. These results indicate that RLVI could be used as a surrogate for NDVI up to a GS maximum LAI of 0.91 m2 m⁻² observed in 2006. Measured mean (± 1 S.D.) GS LAI was 0.67 (± 0.24) m² m⁻² in 2006. LAI accounted for the majority of the variability in Amax at the 30-day time scale, while at shorter time scales air temperature was the dominant control. For 2004 to 2007, mean spring estimates of LAI were 0.25, 0.29, 0.38 (compared to 0.40 m² m⁻² from measurements) and 0.41 m² m⁻², respectively. Results suggest that a steady increase in the jack pine LAI component accounted for the annual increases in GPP and hence NEP over the four years. / Land and Food Systems, Faculty of / Graduate

The aim of this thesis is to design a mechanical position securing of hydraulic elevating systems for stage technology. The first part includes an overview of present state of elevating systems and their securing solutions. The second part determines technical parameters and design of a chosen solution together with control and design calculations. Final part analyses suggested solution in terms of security.

Diploma thesis deals with the design of transfer table for steel sheets with stroke using screw jacks. The thesis contains a technical balance sheet construction of electromechanical and hydraulic transfer table. The main work is a description of the conceptual solutions and description of selected components. The thesis includes calculations wheel drive and stroke, design and control wheel blocks and traversing chain. End of thesis includes strength finite element analysis with the determination of the maximum stress and strain. The work accompanying drawings.

Several available free software audio solutions were analyzed, and Jackdmp—a C++ reimplementation of the renowned JACK Audio Connection Kit—was selected as the most appropriate solution for a real-time audio architecture on DROPS. The JACK sound architecture provides the lowest processing latency possible on a desktop computer for a given set of sound card parameters. It reduces the latency jitter caused by software to zero and synchronizes streams at sample accuracy. A real-time admission scheme for JACK clients is proposed. The execution time of different typical JACK clients was analyzed with measurements to validate the assumptions the proposal is based on, but also to gain further knowledge about their timing behavior. The measurements showed that the condition set by Paul Davis—the time to process a client must be a linear function of the buffer size—holds for all tested clients. Jackdmp was ported to DROPS. The developed design of the port and its implementation is documented here. Measurements showed that—although the real-time performance of the Linux kernel is continuously being improved in the mainline and on special external branches—DROPS can provide a signaling latency that is two times lower on average than the values that can be achieved on the same machine running with a low latency patched Linux kernel. Thus, it can be stated that DROPS is well-suited for real-time audio processing and that the pursued path to use it as the foundation of a truly real-time capable audio workstation should be followed. / Wenn man heute digitale Audiotechnik zum Aufnehmen oder Abmischen von Musik oder anderen Audiodaten verwenden möchte, steht man vor der Wahl, entweder auf eine sehr spezialisierte Hardwarelösung zurückzugreifen oder aber sich eines gewöhnlichen Desktopsystems mit entsprechender Audiosoftware zu bedienen. Der Vorteil eines Desktopsystems ist neben seinem deutlich niedrigeren Preis vor allem die Flexibilität. Bezüglich seines Echtzeitverhaltens bietet ein Computer mit einem Standard-Desktop-Betriebssystem aber bei weitem nicht dieselbe Verlässlichkeit einer spezialisierten Hardwarelösung oder analoger Technik. Die Architektur von DROPS --- mit dem echtzeitfähigen Fiasco- Mikrokern auf der einen Seite sowie der Unterstützung von Legacy-Anwendungen durch L4Linux auf der anderen Seite --- birgt die Hoffnung, die Vorteile von den beiden eben beschriebenen Welten auf einem System mit DROPS kombinieren zu können. Die Motivation meiner Arbeit war es, für dieses langfristige Ziel einen ersten Grundstein zu legen. Dazu war es meine Aufgabe, verschiedene Open-Source- Lösungen hinsichtlich ihrer Eignung als Echtzeit-Audioarchitektur für DROPS zu analysieren und die am besten geeignete auf L4Env zu portieren. Meine Wahl fiel dabei auf das in der Linux-Audio-Szene wohlbekannte Jack Audio Connection Kit (JACK). Desweiteren konnte ich in der Arbeit untersuchen, wie sich die JACK Audioarchitektur in ein globales Echtzeit-Scheduling --- z.B. eines von DROPS --- einbetten ließe, und schlage eine generische Methode dafür vor.

Ulf Lundell is one of the most famous songwriters and authors in Sweden. He has written fifteen works of fiction and they’ve all same theme – a lonely man trying to look into his own past life. They are all built on a character, writing from an I-perspective, having a bit of Lundells own biography in there’s personality.  The aim of his thesis is to find out how Ulf Lundell presents him self in his fictive characters, and will trace the authors development from a psychological point of view. The theoretic starting points are Lacans Freudian concepts “idealego”, “egoideal” and “the superego”, describing the psychological alteration at the author.                    The examination contains an analysis of Lundells novels Jack, En varg söker sin flock and Värmen, and throws light on the relationship between the author and his characters, and how it developes and changes with Lundells literary development. In this consideration are narrative theories a basic factor.   This work will also try to illustrate what has inspired Lundell in creating his fiction figures, and finally how he creates his own lived life on these literary characters.