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An exemplar-based approach to search-assisted computer-aided diagnosis of pigmented skin lesionsZhou, Zhen Hao (Howard) 15 November 2010 (has links)
Over the years, exemplar-based methods have yielded significant improvements over their model-based counterparts in image synthesis applications. Notably, texture synthesis algorithms using an exemplar-based approach have shown success where traditional stochastic methods failed. As an illustrative example, I will present an exemplar-based approach that yields substantial benefits for user-guided terrain synthesis using Digital Elevation Models (DEMs). This success is realized through exploitation of structural properties of natural terrain. In addition to their proliferation in the image synthesis domain, as annotated image datasets become increasingly available, exemplar-based methods are also gaining in popularity for image analysis applications.
This thesis addresses the intersection between exemplar-based analysis and the problem of content-based image retrieval (CBIR). A basic problem in CBIR is the process by which the search criteria are refined by the user through the manipulation of returned exemplars. Exemplar-based analysis is particularly well-suited to query refinement due to its interpretability and the ease with which it can be incorporated into an interactive system. I investigate this connection in the domain of Computer-Assisted Diagnosis (CAD) of dermatological images. I demonstrate that exemplar-based approaches in CBIR can be effective for diagnosing pigmented skin lesions (PSLs). I will present an exemplar-based algorithm for segmenting PSLs in dermatoscopic images. In addition, I will present a generalized representation of dermoscopic features for detection and matching. This representation not only leads to an exemplar-based PSL diagnosis scheme, but it also enables us to realize interactive region-of-interest retrieval, which includes a relevance feedback mechanism to facilitate more flexible query-by-example analysis. Finally, I will assess the benefit of this CBIR-CAD approach through both quantitative evaluations and user studies.
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Cervical intraepithelial lesions and integration of human papillomavirus / Intraepiteliniai gimdos kaklelio pokyčiai ir žmogaus papilomos viruso integracijaŠepetienė, Agnė 07 March 2011 (has links)
This dissertation observes the association between human papillomavirus (HPV) integration into the host cell genome and cervical intraepithelial lesions. The aim of this study is to determine how the grade of HPV16 DNA integration into the host cell genome (HPV E2 gene deletion) is related to cervical intraepithelial lesions. 253 women were screened for HPV infection and the majority was diagnosed with HPV type 16. The most frequently determined was HPV grade II integration. No statistically significant difference was defined while analyzing the relations between the status of HPV E2 gene integration and the grade of cervical intraepithelial lesions. The fact that integration of HPV type 16 was determined in low grade cervical squamous intraepithelial lesions or in cases with no intraepithelial lesions shows that virus integration occurs at the early stage of carcinogenesis. It is noteworthy that during the follow-up (secondary visit after 6 month) 50% of HPV positive women were identified with mRNR expression which probably establishes the presence of persistent active HPV infection. The research provided is highly significant for improvement of cervical cancer screening programms. Adjusting Pap smear, HPV DNA detection and determination of other HPV biomarkers (such as E2 gene deletion mRNR), it becomes possible to separate out HPV positive women with no clinical signs, although, belonging to the of high risk group for cervical carcinoma developing. / Disertacijoje nagrinėjama sąsaja tarp žmogaus papilomos viruso (ŽPV) integracijos į gimdos kaklelio epitelio ląstelių genomą ir intraepitelinių gimdos kaklelio pokyčių. Pagrindinis darbo tikslas – nustatyti, kaip 16 tipo ŽPV DNR integracijos laipsnis (ŽPV E2 geno iškrita) susijęs su intraepiteliniais gimdos kaklelio pokyčiais. Ištyrus 253 moteris nustatyta, kad dauguma moterų buvo infekuotos 16 tipo ŽPV. Dažniausiai nustatyta II laipsnio šio tipo ŽPV integracija. Statistiškai reikšmingo skirtumo analizuojant sąsajas tarp ŽPV E2 geno integracijos pobūdžio ir intraepitelinių gimdos kaklelio pokyčių laipsnio nenustatyta. Tai, kad integruotų 16 tipo ŽPV formų nustatyta esant nežymių arba net nesant intraepitelinių gimdos kaklelio pokyčių, rodo, jog viruso integracija yra ankstyvasis kancerogenezės įvykis. Pažymėtina, kad pakartotinio patikrinimo metu 50 proc. ŽPV infekuotų moterų konstatuota mRNR raiška, kas rodo besitęsiančią aktyvią ŽPV infekciją. Atliktas tyrimas yra svarbus gerinant patikros dėl gimdos kaklelio patologijos programas: derinant Pap testą ir ŽPV DNR bei kitų ŽPV žymenų nustatymą (mRNR, E2 geno iškrita) galima atrinkti infekuotas ŽPV moteris, kurioms dar nėra klinikinių požymių, tačiau jos priklauso didelės rizikos susirgti gimdos kaklelio vėžiu grupei.
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Prognostische Aussagekraft von White Matter Lesions auf den kognitiven Verlauf bei Patienten mit zerebraler Mikroangiopathie / Prognostic value of white matter lesions with change in cognitive decline in patients with cerebral small vessel diseaseResech, Friderike 18 November 2014 (has links)
No description available.
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Kiaulių poskerdiminio tyrimo rezultatų analizė / Incidence Analysis of Organ and Tissue Lesions in Post-Slaughter HogsVerbickas, Tadas 05 March 2014 (has links)
Mokslinis tiriamasis darbas buvo vykdomas 2012–2014 metais Lietuvos sveikatos mokslų universiteto Veterinarijos akademijos ir X mėsos įmonės skerdykloje. Darbo apimtis 51 puslapis, darbe pateiktos 7 lentelės, 5 paveikslai, priede pateiktos 6 lentelės.
Darbo pavadinimas: Kiaulių poskerdiminio tyrimo rezultatų analizė.
Darbo tikslas: Atsižvelgiant į žaliavos tiekėją, nustatyti kiaulių poskerdiminio tyrimo metu nustatomus pakitimus.
Darbo uždaviniai:
nustatyti iš skirtingų ūkių tiekiamoms kiaulėms poskerdiminio tyrimo metu nustatomus pakitimus;
nustatyti iš skirtingų ūkių tiekiamoms kiaulėms poskerdiminio tyrimo metu 10 dažniausiai nustatomų pakitimų;
nustatyti vienu metu tos pačios kiaulės organuose ir audiniuose nustatomų pakitimų kiekį.
Tyrimo rezultatai: skerdžiamų kiaulių poskerdiminio tyrimo metu randamų pakitimų analizė reikšminga, nes bet koks gyvulio sveikatos sutrikimas ne tik sukelia tam tikrų organų pažeidimus, bet ir tiesiogiai veikia skerdžiamų gyvulių skerdenų sanitarinę būklę bei kokybę, tai yra itin svarbi maisto kontrolės grandinės dalis, užtikrinant maisto saugumą, o kartu ir visuomenės sveikatą. Tiriamuoju laikotarpiu mėsos įmonėse daugiausia kiaulių (79,9 proc.) buvo paskersta iš Lietuvos ir Estijos pramoninių fermų (kompleksų), tik 2,10 2,32 proc. kiaulių paskersta iš nedidelių žemės ūkio bendrovių ir ūkininkų fermų (p<0,001). Poskerdiminio tyrimo metu 12,75 proc. kiaulių rastas vienas pakitimas, 2,79 proc. kiaulių rasti du pakitimai, 0,87 proc... [toliau žr. visą tekstą] / The research investigation was conducted during 2012–2014 at the Lithuanian University of Health Sciences Veterinary Academy and in the meat-processing company abattoir. The investigation includes 51 pages, 7 tables and 5 graphics. 6 tables are presented in the appendix.
Title: Incidence Analysis of Organ and Tissue Lesions in Post-Slaughter Hogs
Objective: Determine the incidence of organ and tissue lesions (hereinafter – lesions) in post-slaughter hogs results in respect to producer farm.
Assignments:
1. Determine lesions in post-slaughter hogs from different producer farms.
2. Determine the primary 10 lesions found in post-slaughter hogs.
3. Determine the amount of lesions found simultaneously in one hog.
Investigation results: The analysis of lesions in post-slaughtered hogs is significant. Any health disorder of an animal not only causes various organ or tissue lesions but it also directly affects the hygiene and quality of meat which is notably important within the food chain and in protecting public health. During the investigation period at the meat-processing plant, the origin of most hogs (79.9%) were from Lithuanian and Estonian industrial farms (complexes) and 2.10 – 2.32% were produced at smaller agricultural companies or farms (p<0.001). The post-slaughter investigation results showed one lesion in 12.75% of hogs, two lesions in 2.79%, three lesions in 0.87%, four lesions in 0.18%, five lesions in 0.03% and more than five lesions in 0.01% of hogs. One lesion was... [to full text]
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Optical coherence tomography : technology enhancements and novel applicationsSilva, K.K.M. Buddhika Dilusha January 2004 (has links)
In the last fifteen years, a great deal of effort has been put forth, worldwide, for investigating and enhancing various aspects of optical coherence tomography (OCT). This thesis begins with a description of the technique of OCT, and an analysis of its underlying theory. The design and construction of an OCT system is described, with particular emphasis on a novel delay scanning method, and novel signal processing. Application of OCT to non-destructive characterisation of seeds, examination of skin lesions, measurement of fluid flow, and refractive index determination, are then demonstrated. Two technological enhancements to OCT are presented in this thesis. The first, an extended-range Fourier domain optical delay line (FDODL), extends the scan range of the traditional FDODL by a factor of almost 9, by scanning the galvanometer mirror around the region of zero tilt-angle. Polarisation optics are used to prevent light coupling back into the interferometer after only a single pass through the FDODL. A non-coplanar version of the FDODL is also presented, which overcomes the losses associated with the polarisation-based design, but trades off scan range to do so. Both versions of FDODL demonstrated excellent linearity and scan uniformity. The second technology presented here, bifocal optical coherence refractometry (BOCR), affords OCT the ability to measure refractive indices within turbid media. It achieves this by generating two confocal gates within the sample. From knowledge of the system parameters, and measurements of the confocal gate separation, the refractive index within the medium is evaluated to within ±0.01. Refractive index mapping is then demonstrated in a number of turbid samples. Three other applications of OCT are also demonstrated in this thesis. The first is the use of OCT to measure full thickness in lupin seeds. Although OCT could not penetrate the entire thickness of the hull, it is demonstrated that the variation in thickness of the two layers observed with OCT, explained 81% of the variation in thickness of the entire hull measured under a SEM. OCT was then applied, for what is believed to be the first time, in a large scale seed screening program. The second application is a preliminary investigation of the suitability of OCT to aid in the diagnosis of skin lesions. Although our system did not possess sufficient positioning accuracy to enable a direct one-to-one comparison between OCT and histology, a number of correspondences between OCT and histology images were demonstrated. The final application of OCT demonstrated here is a novel phase-locked-loop based demodulation scheme, to perform Doppler OCT. This demodulation scheme demonstrated a dynamic range of 98dB, a velocity range of ±20mm/s, and velocity resolution of 0.5mm/s. Using this system, laminar flow was demonstrated in milk flowing through a capillary tube.
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Leptospira infection among pigs in southern Vietnam : aspects on epidemiology, clinical affection and bacteriology /Boqvist, Sofia, January 2002 (has links) (PDF)
Diss. (sammanfattning) Uppsala : Sveriges lantbruksuniv., 2002. / Härtill 4 uppsatser.
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LESÕES DO SISTEMA URINÁRIO EM CÃES / LESIONS OF THE URINARY SYSTEM IN DOGSInkelmann, Maria Andréia 16 March 2012 (has links)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / This thesis was composed of three scientific papers. The first paper was the more
comprehensive. All lesions of the urinary system of dogs necropsied between 1999 and 2010 were
analyzed. In this time frame, 3,189 dogs were necropsied at the Laboratório de Patologia Veterinária
of the Universidade Federal de Santa Maria (LPV-UFSM) and 1,063 had lesions in the urinary system.
In most of the dogs (79.1%), lesions were single and in about 21% they were multiple, totalizing 1,373
lesions. Kidneys were 2.8 times more affected than the lower urinary tract (LUT). One third of the
lesions in the urinary system were cause of spontaneous death or reason for euthanasia (SD/EUTH) of
the affected dogs. The other lesions were considered incidental findings. The main renal lesions
diagnosed were: tubulointerstitial nephritis, infarct, granulomatous nephritis, glomerulonephritis,
metastatic/multicentric neoplasms, pyelonephritis/pyelitis, and hydronephrosis. The main LUT lesions
were: cystitis, presence of viral inclusions bodies, urolithiasis, urinary bladder dilatation, urinary
bladder rupture, and metastatic/multicentric neoplasms. Epidemiological aspects such as gender,
breed, and age of affected dogs had significant variations according to the type of lesion diagnosed.
Uremia was observed in a significant number of cases of SD/EUTH and was mostly due to renal
lesions. The second paper was focused on urolithiasis. From 1990 to 2010, 4,872 dogs were
necropsied at LPV-UFSM. Out of these, 1.5% had uroliths along the urinary tract. The
epidemiological profile of the affected dogs showed predominance of males; adults; and pure breeds.
Clinical signs suggestive of urolithiasis were informed in 30.3% of the dogs and consisted mainly of
hematuria, anuria, dysuria and urinary incontinency. The uroliths were found in one or more
anatomical sites, and the main affected ones, in descending order, were urinary bladder, kidney, and
urethra. Secondary lesions to urolithiasis were observed in about 40% of the cases. The most prevalent
were cystitis, urethral obstruction, hydroureter, hydronephrosis, urinary bladder rupture, and
pyelonephritis. In 25% of the affected dogs, SD/EUTH occurred due to the secondary lesions of
urolithiasis. Extra-renal lesions of uremia were observed in 9 out of the 76 cases. The third article was
focused on urinary system neoplasms of dogs. The main purposes of this study were to establish the
prevalence and types of primary and metastatic/multicentric neoplasms of the urinary system in dogs
submitted to necropsy in about 21 years at the LPV-UFSM. Neoplasms of the urinary system were
present in 113 (2.4%) dogs. Twenty seven were primary neoplasms and 86 were metastatic or part of a
multicentric tumor. The majority of the primary neoplasms were of epithelial origin. Thirteen dogs had
primary renal neoplasms (prevalence of 0.27% over all dogs necropsied).
Cystadenocarcinoma/cystadenoma and renal cell carcinoma were the most prevalent primary renal
neoplasms and transitional cell carcinoma was the most prevalent urinary bladder neoplasm.
Metastatic or multicentric tumors affecting the urinary system were the most prevalent (76.1%);
mesenchymal tumors were more common than epithelial tumors; most of them were localized in the
kidney. Metastases of mammary tumors and multicentric lymphoma were the most prevalent
histologic types. / Esta tese foi constituída de três partes que resultaram em três artigos científicos. O primeiro
artigo foi o mais abrangente, onde todas as lesões do sistema urinário em cães necropsiados entre 1999
e 2010 foram analisadas. No período estudado foram necropsiados 3.189 cães no Laboratório de
Patologia Veterinária da Universidade Federal de Santa Maria (LPV-UFSM) e destes, um terço
(1.063) apresentou lesões no sistema urinário. Na maioria (79,1%) dos cães foram observadas lesões
únicas e em aproximadamente 21% havia lesões múltiplas, totalizando 1.373 lesões. Os rins foram 2,8
vezes mais afetados que o trato urinário inferior (TUI). Um terço das lesões no sistema urinário foram
causa de morte espontânea/eutanásia (ME/EUT). As demais foram consideradas achados incidentais.
As principais lesões renais diagnosticadas foram: nefrite túbulo-intersticial, infarto, nefrite
granulomatosa, glomerulonefrite, neoplasmas metastáticos/multicêntricos, pielonefrite/pielite e
hidronefrose. As principais lesões do TUI diagnosticadas foram: cistite, presença de inclusões virais,
urolitíase, dilatação da bexiga, ruptura de bexiga e neoplasmas metastáticos/multicêntricos. As
características epidemiológicas como sexo, raça e idade dos cães afetados tiveram variações
significativas de acordo com o tipo de lesão diagnosticada. Uremia foi observada em um número
significativo de casos de ME/EUT e foi, principalmente, secundária a lesões renais. O segundo artigo
enfocou a urolitíase. No período analisado (1990 2010) foram necropsiados 4.872 cães. Destes, 1,5%
apresentaram urólitos ao longo do sistema urinário. O perfil epidemiológico mostrou o predomínio de
cães machos; adultos; e com raça definida. Sinais clínicos indicativos de urolitíase foram computados
em cerca de um terço dos casos e consistiram principalmente de hematúria, anúria, disúria e
incontinência urinária. Os urólitos tiveram localização única ou múltipla e os locais anatômicos mais
frequentemente acometimentos, em ordem decrescente de prevalência, foram bexiga, rim e uretra.
Lesões secundárias à urolitíase foram observadas em aproximadamente 40% dos cães afetados. As
mais prevalentes foram cistite, obstrução uretral, hidroureter, hidronefrose, ruptura vesical e
pielonefrite. Em 25% do total de cães afetados ocorreu ME/EUT decorrentes das lesões secundárias à
urolitíase. Uremia foi observada em 9 dos 76 casos. O terceiro artigo enfocou os neoplasmas que
acometem o sistema urinário de cães. Nesse estudo foram determinados a prevalência e os tipos de
neoplasmas primários e metastáticos/multicêntricos que ocorreram no sistema urinário de cães
recebidos para necropsia no LPV-UFSM num período de aproximadamente 21 anos (janeiro de 1990
julho de 2010). Em 113 (2,4%) dos cães necropsiados no período estudado, foram diagnosticados 27
neoplasmas primários e 86 metastáticos ou como parte de tumores multicêntricos no sistema urinário.
Dos neoplasmas primários, a grande maioria teve origem epitelial. Treze casos eram neoplasmas
renais primários (0,27% do total de cães necropsiados). Cistadenocarcinoma/cistadenoma e o
carcinoma de células renais foram os neoplasmas primários mais prevalentes no rim e o carcinoma de
células de transição foi o mais prevalente na bexiga. Os neoplasmas metastáticos e multicêntricos que
afetaram o sistema urinário foram os mais prevalentes (76,1%), com predomínio mesenquimal. Destes,
a grande maioria estava localizada no rim e, quanto ao tipo histológico, as metástases de neoplasmas
mamários e o linfoma multicêntrico predominaram.
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Avaliação clínica longitudinal de restaurações de resina composta em lesôes cervicais não cariosas utilizando as técnicas direta e semidireta: estudo randomizado. / Clinical longitudinal evaluation of composite resin restorations in non-carious cervical lesions using direct and direct-indirect techniques: a randomized study.Elia, Laura Célia Fernandes Meirelles 08 December 2018 (has links)
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Previous issue date: 2018-12-08 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / O objetivo desse estudo clínico randomizado boca dividida foi avaliar longitudinalmente a efetividade de restaurações de resina composta de lesões cervicais não cariosas realizadas pelas técnicas direta e semidireta. Foram selecionados 30 pacientes voluntários com necessidade de restaurações cervicais do tipo classe V. Cada paciente recebeu duas restaurações, uma realizada pela técnica direta e outra através da técnica semidireta, totalizando 60 restaurações. Após a realização das restaurações, foi feita uma avaliação inicial imediata (baseline), após 7 dias, 6, 12 e 24 meses, por meio dos critérios USPHS modificado. Cada paciente foi avaliado a cada retorno por dois examinadores calibrados. A análise dos dados foi realizada através de estatística descritiva por meio de porcentagem de sucesso das restaurações de acordo com os critérios estudados e os escores obtidos. Para análise inferencial foi realizado o teste T Student para avaliar as diferenças entre extensão, profundidade e tempo. Os testes Qui-Quadrado/Fisher foram utilizados para comparação das taxas entre os grupos após cada período (p<0,05). Os resultados obtidos foram avaliados por testes de sobrevida e taxa anual de falha (Kaplan-Meier). Em relação ao tempo, foi observada diferença estatisticamente significante, sendo a técnica direta 21,8 min (± 14,50) mais rápida que a técnica semi direta 35,3 min (± 19,89). Das 60 restaurações realizadas, 1 restauração direta foi perdida por falha de retenção e nenhum paciente faltou ao retorno em 7 dias. Com 6 meses, 4 restaurações foram perdidas por falta de retenção na técnica direta e 5 restaurações foram perdidas pelo mesmo motivo na técnica semi-direta. Somente 1 paciente se ausentou. No retorno de 12 meses, 2 restaurações foram perdidas e 2 pacientes ausentaram-se em ambas as técnicas. E com 24 meses, 2 pacientes não compareceram ao retorno e nenhuma restauração falhou pelo critério retenção pela técnica direta. Na técnica semi-direta, 1 paciente ausentou-se e 1 restauração foi perdida por falta de retenção. O sucesso cumulativo da técnica direta foi de 99%, 93,1%, 88,5% e 88,5% nos períodos de 7 dias, 6, 12 e 24 meses respectivamente. Na técnica semi-direta o sucesso cumulativo foi de 100%, 92,8%, 88,4% e 83,7% nos períodos de 7 dias, 6, 12 e 24 meses respectivamente. Conclui-se que, independente da técnica empregada, ambas são boas opções restauradoras e possuem altas taxas de sucesso cumulativo nos períodos estudados. O tempo de trabalho foi superior na técnica semidireta que na técnica direta. Com o passar do tempo houve redução da sensibilidade dental em ambas as técnicas. Houve trauma gengival imediatamente após os procedimentos restauradores realizados com as duas técnicas, porém houve redução do mesmo no decorrer dos períodos avaliados. / The purpose of this randomized split-mouth clinical study was to longitudinally evaluate the effectiveness of composite resin restorations of non-carious cervical lesions performed by direct and semi-direct techniques. A total of 30 volunteers with a need for class V cervical restorations were selected. Each patient received two restorations, one performed by the direct technique and the other by the directindirect technique, totaling 60 restorations. Assessment at baseline, 7 days, 6, 12 and 24 months, we performed using the modified USPHS criteria. Each patient was evaluated at return by two calibrated examiners. Data analysis was performed through descriptive statistics analysis using percentage of success of the restorations according to the criteria studied and scores obtained. For inferential analysis, the Student T test was used to evaluate the differences between extension, depth and time. Chi-Square/Fisher tests were used to compare rates between groups after each period (p <0.05). The results were evaluated by survival and annual failure rates (Kaplan-Meier). Differences were detected regarding to time, in which direct and direct-indirect procedures last 21.8(± 14.50) and 35.3 (± 19.89) minutes, respectively. Of the 60 restorations performed, 1 direct restoration was lost due to retention failure and no patient was missing the return in 7 days. At 6 months, 4 restorations were lost due to lack of retention in the direct technique and 5 restorations were lost for the same reason in the direct-indirect technique. Only 1 patient was absent. At 12 months return, 2 restorations were lost and 2 patients were absent in both techniques. And at 24 months, 2 patients did not attend the return and no restoration failed by the retention criterion by the direct technique. In the direct-indirect technique, 1 patient was absent and 1 restoration was lost due to lack of retention. The cumulative success of the direct technique was 99%, 93.1%, 88.5% and 88.5% in the 7-day, 6th, 12th and 24thmonths periods respectively. In the direct-indirect technique, cumulative success was 100%, 92.8%, 88.4% and 83.7% in the 7-day, 6, 12 and 24-month periods, respectively. It is concluded that, regardless of the technique employed, both are good restorative options and have high cumulative success rates in the studied periods. Working time was longer in the direct-indirect technique than in the direct technique. There was reduction of dental sensitivity in both techniques. There was gingival trauma immediately after the restorative procedures performed by the two techniques, with trauma reduction with the along the evaluated periods.
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Estudo das características e dos fatores de risco de lesões cervicais não cariosas em serviços de oclusão na ParaíbaFigueiredo, Viviane Maria Gonçalves de 01 December 2011 (has links)
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Previous issue date: 2011-12-01 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / The objective of this study to verify the characteristics and risk factors related to the development of non-carious cervical lesions on Services of Occlusion in Paraiba. Through a quantitative, cross-sectional, observational and prospective study evaluated 88 patients of both sexes, females (63.6%) and male (36.4%) between 18 and 71 years with a mean age of 31 years, in services of occlusion of the cities of João Pessoa and Campina Grande. Clinical evaluations were performed to observe the characteristics and diagnose risk factors (abrasive, erosive and occlusal) of non-carious cervical lesions. Through descriptive analysis and non-parametric, 5% significance level and 95% confidence interval. There was a prevalence of 65.90% of patients with lesions, and 461 teeth affected by the same. The group of premolars was the hardest hit by lesions, which are frequently presented in the study on the facial surface, rounded, supragengival and index of tooth wear with degree 1. Gender was not associated with the presence of lesions, whereas age was statistically significant (p <0.001) for the presence of these. Consumption of fruits, unilateral mastication, occlusal interferences in maximum intercuspation and hand no-work were considered risk factors for the development of these lesions. The non-carious cervical lesions have a multifactorial etiology, exposure to risk factors, over time, promotes their development. / Objetivou-se verificar neste estudo as características e os fatores risco relacionados ao desenvolvimento de lesões cervicais não cariosas em Serviços de Oclusão na Paraíba. Por meio de um estudo quantitativo, transversal, observacional e prospectivo, foram avaliados 88 pacientes, de ambos os sexos, feminino (63,6%) e masculino (36,4%); entre 18 e 71 anos, com média de idade de 31 anos, nos Serviços de Oclusão das cidades de João Pessoa e Campina Grande. Realizaram-se avaliações clínicas para observar as características e diagnosticar os fatores risco (abrasivos, erosivos e oclusais) das lesões cervicais não cariosas. Através de análises descritivas e não paramétricas, com 5% de nível significância e 95% de intervalo de confiança. Verificou-se a prevalência de 65,90% dos pacientes com lesões, e 461 dentes acometidos pela pelas mesmas. O grupo dos pré-molares foi o mais atingido pelas lesões, as quais se apresentaram no estudo freqüentes na face vestibular, de forma arredondada, supragengivais e com índice de desgaste dental de grau 1. O gênero não apresentou associação com a presença das lesões, enquanto que a idade foi estatisticamente significante (p<0,001) para a presença destas. O Consumo de frutas, a mastigação unilateral, interferências oclusais em máxima intercuspidação habitual e lado de não trabalho foram considerados fatores de risco para o desenvolvimento destas lesões. As lesões cervicais não cariosas apresentam etiologia multifatorial, a exposição aos fatores de risco, ao longo do tempo, promove o desenvolvimento das mesmas.
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Lesões ulcerativas cutâneas em frangos de corte: estudo histopatológico e epidemiológicoSesterhenn, Renata January 2013 (has links)
Em função de modificações no processo de criação em escala industrial, associado à expansão do setor avícola nas áreas de genética, nutrição e sanidade, as lesões cutâneas em frangos de corte vêm tornando-se cada vez mais importantes. Na atualidade, as principais doenças que afetam a pele de frangos são a celulite, a varíola aviária, o querato-acantoma (QA) ou carcinoma dérmico de células escamosas (CDCE) e as dermatites inespecíficas, estas últimas geralmente associadas a traumatismos. A classificação das doenças cutâneas é imprecisa, uma vez que os critérios de inspeção tendem a agrupar essas lesões cutâneas nas carcaças de frangos de corte em uma única categoria denominada de “dermatose”. As lesões ulcerativas na pele de frangos de corte são causas comuns de condenação total ou parcial de carcaças em matadouros-frigoríficos. O querato-acantoma é uma das causas mais frequentes dessas lesões, sendo de etiologia desconhecida. Por outro lado, lesões ulcerativas macroscopicamente semelhantes às do querato-acantoma e causadas por granulomas do tipo corpo estranho, possivelmente de origem vegetal, vêm sendo observadas em aves abatidas em alguns matadouros-frigoríficos no estado do Rio Grande do Sul (Brasil). Com base nessas premissas, o objetivo desse trabalho foi avaliar histologicamente e analisar os fatores epidemiológicos envolvidos no aparecimento das lesões ulcerativas cutâneas: querato-acantoma e dermatite granulomatosa por corpo estranho (DGCE) em frangos de corte abatidos em matadouros-frigoríficos sob inspeção federal e estadual. Foram analisadas 363 amostras com lesões ulcerativas, de um total de 1.373.989 aves visualizadas. Destas, 169 carcaças foram diagnosticadas como querato-acantoma, representando uma prevalência de 0,012% e 210 carcaças foram diagnosticadas como dermatite granulomatosa por corpo estranho, representando 0,015%, A prevalência encontrada no presente trabalho para QA é similar aos valores encontrados por autores, já a prevalência encontrada para DGCE foi superior à relatada em 2004. Se verificou uma maior prevalência de QA em frangos abatidos em matadouros-frigoríficos sob inspeção federal e mais casos de DGCE nos abatidos em matadouros-frigoríficos sob inspeção estadual. A localização mais frequente das úlceras foi o dorso para o querato-acantoma e o peito para a DGCE. As lesões ulcerativas disseminadas na carcaça foram 100 % diagnosticadas como querato-acantoma. Macroscopicamente as lesões únicas podem ser tanto diagnósticas para querato-acantoma como dermatite granulomatosa por corpo estranho, sendo necessário o exame histopatológico para o diagnóstico definitivo. Houve grande variabilidade dos fatores epidemiológicos envolvidos no aparecimento de lesões ulcerativas de pele, indicando necessidade de novas análises para aumentar a amostragem das amostras. / Due to changes in the husbandry process on an industrial scale, associated with the expansion of the poultry sector in the areas of genetics, nutrition and health, the skin lesions have become increasingly important. At present, the major diseases that affect the skin in broilers are cellulite, fowl pox, the keratoacantoma (KA) or dermal squamous cell carcinoma (DSCC) and nonspecific dermatitis, the latter generally associated with trauma. The classification of skin diseases is inaccurate, since the inspection tend to group these skin lesions in carcasses of broilers in a single category called "dermatosis". The ulcerative skin lesions of broilers are common causes of total or partial condemnation of carcasses in slaughterhouses. The keratoacantoma is one of the most frequent causes of these injuries, and of unknown etiology. On the other hand, ulcerative lesions macroscopically similar to the keratoacantoma and granulomas caused by foreign body, possibly of plant origin, has been observed in some birds slaughtered in slaughterhouse in Rio Grande do Sul (Brazil). Based on these premises, the aim of this study was to histologically evaluate and analyze the epidemiological factors involved in the appearance of ulcerative skin: keratoacantoma and foreign body granulomatous dermatitis (FBGD) in broilers slaughtered in slaughterhouses under federal and state inspection. 363 samples were analyzed with ulcerative lesions, a total of 1,373,989 poultry displayed. Of these, 169 carcasses were diagnosed as keratoacantoma, representing a prevalence of 0.012% and 210 carcasses were diagnosed as granulomatous dermatitis foreign body, representing 0.015%. The prevalence founded in the present work to KA is within the range found by authors in previous works, since the prevalence DSCC was higher than that reported in 2004. There was a higher prevalence of KA in slaughter plants under federal inspection and more cases of DSCC in slaughter plants under state inspection. The most frequent location of ulcers was the back and chest for keratoacantoma for DSCC. Ulcerative lesions disseminated in the housing 100% were diagnosed as keratoacanthoma. Grossly, the lesions can be both unique diagnostic for keratoacanthoma as granulomatous dermatitis, requiring histopathology for definitive diagnosis. With this work, it was concluded that new skin lesions should be analyzed, to increase the sampling of specimens, decreasing the variability among the predisposing skin lesions.
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