Bakgrund: Diabetes typ 2 (DT2) är ett ökande hälsoproblem och sjukdomen innebär att kroppen producerar mindre insulin än kroppens aktuella behov. Övervikt, fysisk inaktivitet, ohälsosamma kostvanor, ärftlighet och stigande ålder är riskfaktorer för att utveckla sjukdomen. För att undvika komplikationer ska ett stabilt blodsocker eftersträvas. Sjuksköterskan ska vara ett stöd och ge kunskap om egenvården, som enligt Orem innebär upprätthållande av hälsa och livskvalitet. Fettsnål kost har under många år rekommenderat. Populariteten kring lågkolhydratskost har under de senaste åren ökat och det förekommer studier som visar att kosten kan vara fördelaktigt för personer med DT2. Syfte: Att beskriva effekter av lågkolhydratkost hos personer med DT2. Metod: Litteraturöversikten har kvantitativ design och innehåller 13 vetenskapliga artiklar. Fribergs analysmodell användes för att analysera artiklarna. Resultat: Lågkolhydratskosten visade en signifikant förbättring i glukos, kroppsmassa och blodfetter. Kosten visade inga stora skillnader mellan variablerna på lång sikt jämfört med andra koster. Det stöd som förekom till deltagarna i studierna visade sig vara betydelsefullt för att uppnå ovanstående effekter och framförallt då det gällde att bevara effekterna över tid. Slutsats: Lågkolhydratskosten medförde positiva effekter på kort sikt och effekterna samvarierade med omfattningen av stöd som ingick i studierna. Trots rädslan för att kosten medför ökad risk för hjärt- och kärlsjukdom påvisade studien inga risker med kosten på kort sikt. Nyckelord: diabetes typ 2, lågkolhydratskost, egenvård, Dorothea Orem, diet. / Background: Diabetes type 2 (DT2) is an increasing health problem. The disease means that the body produces less insulin than the body need. Obesity, physical inactivity, unhealthy diet, heredity and rising age are risk factors for the disease. To avoid complications, a stable blood sugar pursued. The nurse will provide support and give knowledge for self-care, that according Orem means to provide health and quality of life. Low fat diets have for many years recommended. The popularity around low carbohydrate diet has increased in recent years. Studies shows that low carbohydrate can be beneficial for persons with DT2. Aim: To describe the effects of low carbohydrate diets in people with DT2. Method: The literature review with a quantitative design, contains 13 scientific articles. Friberg analysis model was used to analyze the articles. Results: A significant improvement was observed in glucose, body mass and lipids. The diet showed no significant differences between the variables in the long term compared to other diets. The support that occurred to the participants in the studies were found to be significant in order to achieve the above effects and especially when it came to preserve the effects over time. Conclusion: The low carbohydrate diet resulted in short- term positive effects and these effects varied whit the extent of support the studies conducted. Despite fears that the diet increases the risk of cardiovascular disease, studies showed no short-term risks. Keywors: diabetes type 2, low carbohydrate diet, self care, Dorothea Orem, diet

Background Type 2 diabetes is a common disease and the prevalence has increased in large parts of the world. In treatment of diabetes the type of diet is of great importance considering metabolic factors such as glucose level and blood lipids. Which diet that is most beneficial to avoid diabetic complications has been heavily debated in recent decades. This thesis is based on two clinical studies designed to compare the effects of different macronutrients. Methods A clinical trial was designed to compare a low-carbohydrate diet (LCD) to a low-fat diet (LFD) in treatment of patients with type 2 diabetes. Sixty-one patients at two health care centres were included and randomized to get advice to eat a LCD or a LFD. The LCD had an energy content where 50 energy percent (E%) where from fat, 20 E% from carbohydrates and 30 E% from protein. For the LFD the nutrient composition was similar to what is traditionally recommended for treatment of type 2 diabetes in Sweden. Metabolic factors, anthropometrics and questionnaires were analysed. To study postprandial effects a trial was designed to compare three different diets. Twentyone patients with type 2 diabetes were included to in randomized order test the three types of diets on separate test days. On each test day the patients were served breakfast and lunch and blood samples were taken at six times these days. Glucose, lipids and hormones were analysed. Results There were equal weight reduction in the two groups in the first trial during the two-year study period. At six month when compliance was good according to diet-records, the glucose level (HbA1c) was lowered and the HDL-cholesterol was increased in the LCD group. The inflammatory markers IL-6 and IL-1Ra were significantly lower in the LCD group than in the LFD group. At 12 months the physical function, bodily pain and general health  scores improved within the LCD group only. In the second trial the postprandial glucose and insulin levels were lower on the LCD compared to the LFD. However, the LCD resulted in a tendency to higher postprandial triglyceride levels. The Mediterranean type of diet with all energy intake at lunch resulted in a more pronounced insulin response and a glucose level at lunch similar to that of the low-fat diet. The increase-ratio of insulin correlated to the elevation of the incretin glucose-dependent insulinotropic peptide (GIP). Conclusions In the two-year study we found benefits for the LCD group regarding glucose control and insulin doses. Furthermore, only the LCD was found to improve the subclinical inflammatory state and there were some aspects of improved well-being in this group. Aiming for 20% of energy intake from carbohydrates is safe with respect to cardiovascular risk factors  compared with the traditional LFD and this approach could constitute a treatment alternative. In the postprandial state, the LCD induced lower insulin and glucose excursions than the LFD but at the same time a tendency of higher triglycerides. The long-term significance needs to be further examined. The accumulation of caloric intake from breakfast to lunch to a single large Mediterranean-style lunch-meal in type 2 diabetes might be advantageous from a metabolic perspective.

Bakgrund: Diabetes typ-2 är en av Sveriges största folksjukdomar. Orsakerna till sjukdomen är både genetiska och miljörelaterade. De miljörelaterade faktorerna är främst övervikt och fetma. Diabetes typ-2 kan behandlas med kost, motion, tabletter eller insulin. Kosten har en central roll i behandlingen av diabetes typ-2 och kan ge effekter på både blodsocker och vikt. Syfte: Syftet är att belysa vad och hur sjuksköterskor kan göra för att främja en god kosthållning för patienter med diabetes typ-2. Metod: I denna litteraturstudie har tio studier analyserats och sammanställts i resultatet. Resultat: Både sjuksköterskor och patienter har en brist på kunskap om diabetes typ-2. Sjuksköterskor upplevde därför att de hade svårigheter att ge patienter adekvata kostråd. Stöd och patientundervisning från sjuksköterskor är viktigt för att främja en god kosthållning. I resultatet framkom det att en låg-kolhydratkost är en effektiv kost för att gå ned i vikt och sänka HbA1c för personer med diabetes typ-2. Resultatet delades in i två kategorier: hur sjuksköterskor kan främja god kosthållning och vilken kost sjuksköterskor kan använda för att främja en god kosthållning. Slutsats: Stöd och patientundervisning från sjuksköterskor var en viktig del för att främja egenvården av kost för personer med diabetes typ-2. Slutsatsen visar på att deltagarna i studierna som åt en lågkolhydratkost gick ner i vikt och HbA1c sänktes. Klinisk betydelse: I föreliggande studie presenteras hur och vad sjuksköterskor kan göra för att främja egenvården hos patienter med diabetes typ-2 genom stöd, patientundervisning och kost. Studien kan användas som grund för sjuksköterskor som undervisar i egenvård för patienter med diabetes typ-2. / Background: Type-2 diabetes is one of Sweden´s major national diseases. The causes of the disease are both genetically and environmentally related. The environmental factors are primarily overweight and obesity. Type-2 diabetes can be treated with diet, exercise, tablets or insulin. Diet has a key role in the treatment of type-2 diabetes and can affect both blood sugar and weight. Aim: The aim is to highlight what and how nurses can do to promote a good diet for patients with type-2 diabetes. Method: In this literature study ten scientific articles has been analyzed and put together in the results. Results: Both nurses and patients had a lack of knowledge about type-2 diabetes. Nurses felt that they had difficulties to give the patients adequate dietary advices. Support and patient education from nurses is important to promote a good diet. The results showed that a low-carbohydrate diet is an effective diet for losing weight and lower the HbA1c for people with type-2 diabetes. The results were divided into two categories: how nurses can promote a healthy diet and which diet nurses can use to promote a healthy diet. Conclusion: Support and patient education from nurses were an important part of promoting self-care of diet for people with diabetes type-2. The conclusion shows that the participants in the studies who were on a low-carbohydrate diet lost weight and lowered their HbA1c. Clinical significance: This study presents how and what nurses can do to promote self-care in patients with type 2 diabetes through support, patient education and diet. The study can be used as a basis for nurses who teach patients with type-2 diabetes about self-care.

Syftet med denna studie var att undersöka familjers upplevelser av att minimera intaget av socker/snabba kolhydrater. Detta genomfördes med kvalitativa ostrukturerade intervjuer där föräldrarna i familjen fritt fick berätta utifrån olika teman. Dessa teman täckte områden som anledning, tillvägagångssätt, reaktioner, svårigheter, beteenden och eventuella hälsovinster relaterade till kostomläggningen. Utöver dessa familjer valdes tre bloggar ut inom området lågkolhydratkost. Dessa följdes och analyserades som komplement till intervjuerna. Resultaten tolkades utifrån socialkonstruktivistiskt synsätt och teorin om symbolisk interaktionism. De mest framträdande resultaten var att samtliga som ingått i studien har upplevt förbättringar i sin hälsa, i de flesta fall förbättrades även barnens kognitiva förmåga. Vidare upplevde de att traditionen med sötsaker som både belöning och tröst, är djupt rotad vilket innebar att kostomläggningen inte var så enkel att genomföra utan att få höra epitet som "fanatisk" och "extrem". Ingen av intervjupersonerna uppger att de kan tänka sig att återgå till kolhydratrik kost. / The aim of this study was to examine families' experiences of minimizing the intake of sugar/highcarbs. This has been studied with a qualitative unstructured method with the parents in three families from different free to tell based themes. These themes covered areas like reason, procedures, reactions, problems, behaviors and potential health benefits related to their dietary change. In addition to these families, three blogs were selected in the field of low carbohydrate diets. These were followed and analyzed as a supplement to the interviews. The results were interpreted on the basis of social constructivist approach and the theory of symbolic interactionism. The most prominent findings was that all who entered the study have experienced improvements in their health, in most cases also improved children's cognitive ability . Furthermore , they felt that the tradition of sweets as both reward and comfort, made their dietary change implement difficult without hearing the epithet as " fanatical " and " extreme" . None of the interviewees stated that they would be willing to return to the high-carbohydrate diet.

Cancer is the second leading cause of death in the United States. Evidence shows that a conventional western diet may contribute to the proliferation of cancer cells, affecting their prognosis. The aim of this review is to examine the efficacy and safety of using the ketogenic diet as an adjuvant to traditional cancer therapy. The systematic literature search was performed in October 2018 on two search engines: EBSCOhost (Medline, CINHAL, Cochrane Central Register of Controlled Trials) and Web of Science using the following key terms: ketogenic diet, high fat & low-carbohydrate diet, Atkins diet, cancer or neoplasms+. The search limitations included clinical studies among adult cancer patients. A total of 544 publications were initially identified. After the first title/abstract screening, 22 articles were eligible for full-text screening; finally, 3 were eligible for data extraction. We synthesized the effects of the ketogenic diet on cancer progression and safety by extracting and summarizing data on 4 items: 1) study characteristics, 2) characteristics of study participants, 3) diet composition and duration, and 4) key findings for efficacy and safety. Although only 3 studies were included, it was observed that more patients who adhered to the ketogenic diet than patients who did not experienced stability of disease and response to treatment. Patients who received the ketogenic diet also experienced a decrease in tumor size, cholesterol, fasting glucose, and triglyceride levels at 90 days. No statistically significant anthropometric changes were experienced; patients weight was maintained. However, more clinical evidence is necessary before applying the ketogenic diet in an oncological setting.

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Bakgrund: I den systematiska litteratur studien Mat vid diabetes (SBU 2010) framgår det att lågkolhydratkost har likartade metabola effekter hos personer med diabetes i jämförelse med en traditionell lågfettskost. Trotts dessa råd visar en undersökning ifrån samma studie att endast 18 % av de tillfrågade sjuksköterskorna kliniskt tillämpade denna typ av kostintervention. Detta tycks vara problematiskt vilket nyligen uttryckts i en rad olika mediala sammanhang. Utöver denna debatt har vi idag också en epidemiskt stor utbredning av patienter med typ 2 diabetes mellitus vilket ställer krav på de allt mer begränsade resurser som finns inom vård och omsorg.  Syfte: Syftet var att beskriva lågkolhydratkostens metabola påverkan hos patienter med Diabetes Mellitus typ 2. Metod: Den elektroniska sökningen av artiklar utfördes i PubMed, CINAHL, Academic Search Elite, Scopus, Web of Science, PsycINFO (2009-2014) samt PMC (2011-2014). 13 artiklar bedömdes utifrån studiedesign, metabola markörer, intervention/kontrollgrupp, inklusions och exklusionskriterer vara lämpliga för studien. Resultat: En övergripande majoritet studierna visade på att lågkolhydratkosten gav signifikant förbättrade metabola markörer och framförallt gällande HbA1c och HDL-kolesterol. Endast en studie visade på ett negativt icke-signifikant resultat. Konklusion: Lågkolhydratkost förefaller utifrån studiens syfte och resultat som ett fullgott alternativ till den traditionella diabeteskost som utgör stora delar av den kostbehandling som patienter med T2DM får idag. Men kan innebära ett stort ansvar i det arbetsätt som sjuksköterskan tillämpar för att stödja och hjälpa en patient med T2DM att nå en god egenvård, hälsa och metabolkontroll  Nyckelord: Typ 2 diabetes mellitus. Lågkolhydratkost. Traditionell diabeteskost. Chronic Care Model. Egenvård. Empowerment. / Background: The systematic literature review Mat vid diabetes (SBU 2010) indicates that a low carbohydrate diet possesses similar metabolic effects in people with diabetes compared to a traditional low-fat diet. Contrary to this advice, a review from the same study portrayed that only 18% of the surveyed nurses clinically applied this type of diet intervention. This seems to be problematic, as was recently expressed in a variety of media. In addition to this debate, health care now also face a widespread epidemic of patients with type 2 diabetes mellitus which in turn puts the increasingly diminished and limited resources in health care under additional pressure.  Aim: The aim of this study was to describe a low-carbohydrate diet and its metabolic effects in patients with Diabetes Mellitus type 2. Method: Included articles in this review was found by searching PubMed, CINAHL, Academic Search Elite, Scopus, Web of Science, PsycINFO (2009-2014) and PMC (2011-2014). 13 articles were assessed to be eligible for this review by assessing study-design, metabolic markers, intervention / control group, inclusion and exclusions criteria.  Results: An overall majority of studies proved that a low carbohydrate diet could result in significantly improved metabolic markers, and in particular the HbA1c and HDL cholesterol. Only one study showed a negative non-significant result. Conclusion: A low-carbohydrate diet seems based on our findings as a viable alternative to the traditional diabetic diet which constitute a large part of the diet treatment that patients with T2DM receives from current healthcare. But this in turn implies that a greater responsibility is taken by the nurse in order to support and help a patient with T2DM to achieve a good self-care, health and metabolic control. Keywords: Type 2 diabetes mellitus. Low carbohydrate diets. Traditional diabetic diet. Chronic Care Model. Self-care. Empowerment.

Bakgrund Diabetes typ II är ett globalt och nationellt växande hälsoproblem. Lågkolhydratkost har väckt debatt i samhället, men har enligt studier resulterat i gynnsamma effekter för patientgruppen. Socialstyrelsen rekommenderar måttlig lågkolhydratkost som en av flera primära alternativ till kosthållning för patienter med diabetes typ II. Syfte Att undersöka diabetessjuksköterskors attityd och kunskap gällande lågkolhydratkost vid diabetes typ II. Metod Kvalitativa semi-strukturerade intervjuer med sju diabetessjuksköterskor inom Uppsalas primärvård. Resultat Diabetessjuksköterskorna hade observerat positiva effekter i sitt kliniska arbete av kolhydratreduktion, men ingen sjuksköterska gav måttlig lågkolhydratkost som rekommendation i första hand till patienterna. Farhågor för att lågkolhydratkost, främst orsakat av ett ökat fettintag, skulle kunna resultera i en ökning av risken för hjärt-kärlsjukdom eller andra negativa hälsoeffekter skildrades. Medvetenheten gällande kostrekommendationer och uppdateringen kring aktuell forskning varierade. Slutsats Medvetenhet och kunskap gällande lågkolhydratkost som kosthållning vid diabetes typ II varierade hos diabetessjuksköterskor inom Uppsalas primärvård. Generellt kunde en negativ attityd till lågkolhydratkost urskiljas. För att upprätthålla en evidensbaserad hälso- och sjukvård är det av största vikt att diabetessjuksköterskor får möjlighet att inom arbetsplatsen hålla sig uppdaterade om aktuella forskningsresultat samt att skapa reflektion kring vilken extern och intern påverkan sjuksköterskor kan exponeras för. / Background Diabetes type II is an increasing problem on a national and global scale. Low carbohydrate diets have created debate in today society, all though it has come to show positive effects in studies made on this patient group. In the national guidelines by The National Board of Health and Welfare moderate low-carbohydrate diet is described as a primary diet recommendation for patients with diabetes type II. Aim To investigate the attitude and knowledge of nursing staff towards low-carbohydrate diets as a method for patients with diabetes type II to achieve positive health benefits. Method Qualitative semi-structured interviews with seven nurses in district health centers in Uppsala, Sweden. Result The nursing staff had observed health benefits as a result from low-carbohydrate diets in their daily clinical work with patient suffering from diabetes type II, yet none of the nurses did suggest patients to eat according to this diet. Apprehensions that low-carbohydrate diets, and specifically the increased intake of fat, would contribute to an increased risk of heart disease or cause other harmful bodily effects over a long period of time were described. The awareness of national guidelines and recommendation did vary widely among the nurses. Conclusion Awareness and knowledge regarding a low carbohydrate diet when it comes to patients with diabetes type II ranged with the diabetic nurses in Uppsala Primary Care. Generally, a negative attitude towards low carbohydrate diet could be distinguished. To maintain an evidence-based health care, it is important that diabetes nurses have the opportunity to be updated of current research and to make reflections on what kind of external and internal influences nurses may be exposed to.