<p> Part A Abstract </p> <p> Temperature coefficients of reactivity for an 37-element reference design of a thorium oxide fuelled, heavy water moderated and cooled reactor, are calculated. The physical processes which determine magnitude and sign of the coefficients are identified and discussed. Results are given for fresh fuel containing equilibrium concentrations of the fission product Xe-135 and with boron control in the moderator. Results are. also -given for fresh fuel with the equilibrium concentration of Xe-135 but without boron contorl for fuel with an exposue of 1.513 n/k barn and for fuel with an exposure of 3.13 n/k barn; each containing appropriate concentrations of 50 separate nuclides and one-pseudo fission product. The fuel temperature coefficient of reactivity is negative for all the cases studied, while the coolant temperature coefficient of reactivity is positive for all the cases studied. The void effect is an increase in reactivity for all cases studied. </p> ////////////////////// <p> Part B Abstract </p> <p> This work has been done with the purpose of studying the validity of Bragg Kleeman rule which states that for combinations of elements, the atomic stopping cross-sections are additive. The validity of Bragg Kleeman rule for low energy He ions has not been conclusively tested for solids. In this work, the comparison with the experimental stopping power of SiC with the additive stopping powers of Si and C has been made experimentally. </p> <p> A thick target technique in the experimental evaluation of the stopping powers is used. This method has some simplicity over the thin target techniques. </p> <p> A calibration of the McMaster University Van-de Graff accelerator was done. Experiments were conducted later using the calibration curves produced. </p> <p> The report contains a brief account on different sources of errors due to the Van-de-Graff accelerator calibration and due to stopping power experiments. </p> / Thesis / Doctor of Philosophy (PhD)

<p>Bluetooth is the de facto standard for short-range wireless communications. Besides Bluetooth Classic (BC), Bluetooth also consists of Bluetooth Low Energy (BLE) and Bluetooth Mesh (Mesh), two relatively new protocols, paving the way for its domination in the era of IoT and 5G. Meanwhile, attacks against Bluetooth, such as BlueBorne, BleedingBit, KNOB, BIAS, and BThack, have been booming in the past few years, impacting the security and privacy of billions of devices. These attacks exploit both design issues in the Bluetooth specification and vulnerabilities of its implementations, allowing for privilege escalation, remote code execution, breaking cryptography, spoofing, device tracking, etc.</p> <p><br></p> <p>To secure Bluetooth, researchers have proposed different approaches for both Bluetooth specification (e.g., formal analysis) and implementation (e.g., fuzzing). However, existing analyses of the Bluetooth specification and implementations are either done manually, or the automatic approaches only cover a small part of the targets. As a consequence, current research is far from complete in securing Bluetooth.</p> <p><br></p> <p>Therefore, in this dissertation, we propose the following research to provide missing pieces in prior research toward completing Bluetooth security research in terms of both Bluetooth specification and implementations. (i) For Bluetooth security at the specification level, we start from one protocol in Bluetooth, BLE, and focus on the previously unexplored reconnection procedure of two paired BLE devices. We conduct a formal analysis of this procedure defined in the BLE specification to provide security guarantees and identify new vulnerabilities that allow spoofing attacks. (ii) Besides BLE, we then formally verify other security-critical protocols in all Bluetooth protocols (BC, BLE, and Mesh). We provide a comprehensive formal analysis by covering the aspects that prior research fails to include (i.e., all possible combinations of protocols and protocol configurations) and considering a more realistic attacker model (i.e., semi-compromised device). With this model, we are able to rediscover five known vulnerabilities and reveal two new issues that affect BC/BLE dual-stack devices and Mesh devices, respectively. (iii) In addition to the formal analysis of specification security, we propose and build a comprehensive formal model to analyze Bluetooth privacy (i.e., device untraceability) at the specification level. In this model, we convert device untraceability into a reachability problem so that it can be verified using existing tools without introducing false results. We discover four new issues allowed in the specification that can lead to eight device tracking attacks. We also evaluate these attacks on 13 Bluetooth implementations and find that all of them are affected by at least two issues. (iv) At the implementation level, we improve Bluetooth security by debloating (i.e., removing code) Bluetooth stack implementations, which differs from prior automatic approaches, such as fuzzing. We keep only the code of needed functionality by a user and minimize their Bluetooth attack surface by removing unneeded Bluetooth features in both the host stack code and the firmware. Through debloating, we can remove 20 known CVEs and prevent a wide range of attacks again Bluetooth. With the research presented in this thesis, we improve Bluetooth security and privacy at both the specification and implementation levels.</p>

Alors que la nouvelle génération de détecteurs directs de matière sombre est en cours de construction, dans l’espoir de trouver de la matière sombre avec une masse inférieure au GeV, il est important de comprendre comment le rayonnement naturel peut produire un fond d’interactions à faible énergie. Cette thèse s’intéressera à la simulation de la diffusion élastique des rayons γ, une source possible de fonds pour les détecteurs de matière sombre sub-GeV. La simulation utilise le logiciel SuperSim basé sur Geant4 afin de modéliser l’expérience SuperCDMS SNOLAB. Une version modifiée du G4JAEAElasticScatteringModel appelée CDMSJAEAElasticScatteringModel a été mise en oeuvre dans SuperSim afin de simuler les mécanismes de diffusion de photon élastiques Rayleigh, nucléaire Thomson et Delbrück. Le CDMSJAEAElasticScatteringModel ajoute la possibilité pour les particules γ de déposer de l’énergie après avoir été diffusées élastiquement. La validité de ces deux modèles a été vérifiée et des erreurs dans le logicielle ont été rencontrées dans leur traitement des distributions d’angle de diffusion des photons qui déterminent les spectres d’énergie déposée. Les sections efficaces totales sont en accord avec la documentation et d’autres sources. Malgré les erreurs logicielles, la simulation définit une limite inférieure sur le taux de diffusion élastique des rayons γ de ∼ 0,01 et ∼ 0,035 photon diffusé élastiquement par kg par an pour les détecteurs SuperCDMS SNOLAB au germanium et au silicium, respectivement. Ces limites inférieures sont définies à l’aide d’une coupure d’énergie de recul de 1 eV. Cela fait de la diffusion élastique des rayons γ une source importante de bruit de fond pour détecteurs SuperCDMS proposés avec des capacités de discrimination ER/NR à des énergies de recul à l’échelle eV. / While the new generation of direct dark matter detectors are being built in the hopes of finding sub-GeV dark matter, it is important to understand how natural radiation can produce a background of low-energy interactions. This thesis will analyze simulating γ-ray elastic scattering, a possible source of background for sub-GeV dark matter detectors. The simulation uses Geant4-based SuperSim software in order to model the SuperCDMS SNOLAB experiment. A modified version of the G4JAEAElasticScatteringModel called CDMSJAEAElasticScatteringModel was implemented into SuperSim in order to simulate the Rayleigh, nuclear Thomson and Delbrück γ-ray elastic scattering mechanisms. The CDMSJAEAElasticScatteringModel adds the ability for the γ particles to deposit energy after being elastically scattered. The validity of both these models was checked, and errors were encountered in their treatment of photon scattering angle distributions which determine the deposited energy spectra. The total cross sections are consistent with the documentation and other sources. Despite the bug, the simulation does set a lower bound on the γ-ray elastic scattering rate of ∼ 0.01 and ∼ 0.035 elastically scattered photon per kg per year for germanium and silicon SuperCDMS SNOLAB detectors, respectively. These lower bounds are set using a 1 eV recoil energy cutoff. In conclusion, γ-ray elastic scattering a significant source of background for proposed SuperCDMS detectors with ER/NR discrimination capabilities at eV-scale recoil energies.

Background: With increasing clinical use of NK-92 cells and their CAR-modified derivatives in cancer immunotherapy, there is a growing demand for efficient production processes of these “off-the-shelf” therapeutics. In order to ensure safety and prevent the occurrence of secondary tumors, (CAR-)NK-92 cell proliferation has to be inactivated before transfusion. This is commonly achieved by gamma irradiation. Recently, we showed proof of concept that low energy electron irradiation (LEEI) is a new method for NK-92 inactivation. LEEI has several advantages over gamma irradiation, including a faster reaction time, a more reproducible dose rate and much less requirements on radiation shielding. Here, LEEI was further evaluated as a promising alternative to gamma irradiation yielding cells with highly maintained cytotoxic effector function. Methods: Effectiveness and efficiency of LEEI and gamma irradiation were analyzed using NK-92 and CD123-directed CAR-NK-92 cells. LEE-irradiated cells were extensively characterized and compared to gamma-irradiated cells via flow cytometry, cytotoxicity assays, and comet assays, amongst others. Results: Our results show that both irradiation methods caused a progressive decrease in cell viability and are, therefore, suitable for inhibition of cell proliferation. Notably, the NKmediated specific lysis of tumor cells was maintained at stable levels for three days postirradiation, with a trend towards higher activities after LEEI treatment as compared to gamma irradiation. Both gamma irradiation as well as LEEI led to substantial DNA damage and an accumulation of irradiated cells in the G2/M cell cycle phases. In addition, transcriptomic analysis of irradiated cells revealed approximately 12-fold more differentially expressed genes two hours after gamma irradiation, compared to LEEI. Analysis of surface molecules revealed an irradiation-induced decrease in surface expression of CD56, but no changes in the levels of the activating receptors NKp46, NKG2D, or NKp30. Conclusions: The presented data show that LEEI inactivates (CAR-)NK-92 cells as efficiently as gamma irradiation, but with less impact on the overall gene expression. Due to logistic advantages, LEEI might provide a superior alternative for the manufacture of (CAR-)NK-92 cells for clinical application.

Nuclear electromagnetic breakup processes at low energy are particularly relevant in the astrophysical context. In this Thesis we analyse the Beryllium-9 photodisintegration reaction, whose inverse process, under certain astrophysical conditions, is related to the Carbon-12 formation. A preliminary study of the Carbon-12 photodisintegration is also carried out. The interaction of these nuclei with a low-energy photon induces a transition to a state consisting of cluster sub-units, the alpha-particles, and possibly a neutron, n. The theoretical study of the cross section in the low-energy regime is conducted by using a three-body ab initio approach. Beryllium-9 exhibits a clear separation of energy scales, since its alpha-alpha-n three-body binding energy is shallow compared to the binding of the alpha-particle. Within this framework a halo/cluster Effective Field Theory (EFT) can be developed. The alpha-alpha and alpha-n effective interactions are defined in momentum space as a series of contact terms, regularized by a momentum-regulator function. The Low Energy Constants are expressed in terms of scattering observables, i.e. scattering length and effective range. A three-body potential is also introduced in the model. Carbon-12 is studied on the same footing. By means of an integral transform approach, the problem of the transition to a state in the continuum can be advantageously reformulated in terms of a bound-state problem: in the calculations we use the Lorentz Integral Transform method, in conjunction with the Non-Symmetrized Hyperspherical Harmonics method. In determining the low-energy photodisintegration cross section, the nuclear current matrix element is evaluated through the electric dipole, or quadrupole, transition operator (Siegert theorem). Since the continuity equation is used explicitly, the contribution of the one-body and the many-body current operators is implicitly included in the calculation. By comparing the results with those obtained by using a one-body convection current, the effect of the many-body terms can be quantified. The dependence of the results on different EFT parameters is discussed, always in connection with the experimental data available in the literature. By following the power counting dictated by the EFT approach for Beryllium-9, the inclusion of different partial waves in the potential model is explored. In addition to a alpha-alpha S-wave, a alpha-n P-wave and a three-body effective interaction, a alpha-n S-wave term is also required to obtain results more consistent with the experimental data. The contribution of the many-body currents to the cross section is found to be non-negligible. Although at an early stage, Carbon-12 results show interesting features. The formalism presented in this Thesis can be extended to study the photodisintegration of Oxygen-16 within a fully four-body ab initio approach.

The subjects of this thesis are low-energy and passive houses. The main objective is to compare the acquisition costs and operating cost of the low energy and passive houses with conventional construction of houses offering the real estate market, respectively evaluating of investments in energy-efficient buildings. Furthermore, the work focuses on the history, properties and basic problems of designing energy efficient buildings with subsequent by an assessment of the advantages and disadvantages of their implementation. Klíčová slova

Thin metallic films with magnetic properties like magnetite are an interesting material in current technological applications. In the presented work the iron oxide films are grown by molecular beam epitaxy on MgO(001) substrates at temperatures between room temperature and 600K. The film and surface structure are investigated by x-ray reflectometry (XRR), x-ray diffraction (XRD) and low energy electron diffraction (LEED). The chemical properties are investigated by x-ray photoelectron spectroscopy (XPS). Furthermore, charge transfer multiplet (CTM) calculations are performed as a means to gain additional information from photoemission spectra. It is shown that only for temperatures higher than 500K the oxide film forms a spinel structure. A previously unobserved (2x1) surface reconstruction in two orthogonal domains is found for various preparation conditions. The application of CTMs results in good quantitative and qualitative agreement to other methods for the determination of the film stoichiometry. In addition CTMs can well describe the segregation of Mg atoms into the oxide film either during film growth or during film annealing. It is found that initially Mg substitutes Fe on all possible lattice sites, only for prolonged treatment at high temperature do Mg atoms favour the octahedral lattice sites of divalent Fe.

Ce travail porte sur l’étude et le développement d’un système innovant de ventilation et de chauffage au bois dans les habitations à basse consommation d’énergie, qui sont appelées à devenir la référence constructive en France dès 2015. Dans ces habitations fortement isolées et particulièrement étanches à l’air, les besoins de chauffage sont très faibles et peuvent être couverts par une source de chaleur d’origine renouvelable, telle que le bois énergie. En outre, l’utilisation d’une ventilation performante s’impose comme étant un critère essentiel pour assurer la bonne qualité de l’air intérieur et peut même devenir l’unique vecteur de chauffage en apportant l’appoint de chaleur sur l’air insufflé dans les différentes pièces de l’habitation. Le système présenté dans cette étude propose ainsi de combiner les avantages d’un appareil de chauffage au bois de petite puissance, ici un poêle à granulés de bois, et ceux d’une ventilation à récupération de chaleur sur l’air extrait, grâce à un conduit échangeur intégré à la cheminée du poêle et relié au réseau de soufflage de la ventilation. Développé en partenariat avec l’industriel POUJOULAT, spécialisé dans la fabrication de conduits de cheminée métalliques, ce conduit échangeur permet de récupérer sur l’air neuf une partie de la chaleur initialement perdue par les fumées et de la distribuer dans toutes des zones de vie de l’habitation, même les plus éloignées de l’appareil au bois. Après avoir défini la configuration de couplage à adopter pour assurer le bon fonctionnement de l’ensemble et garantir à la fois la sécurité et le confort des occupants, les performances de plusieurs prototypes de conduit échangeur sont caractérisées expérimentalement. Les résultats obtenus lors des essais en laboratoire permettent alors d’orienter l’évolution des prochains prototypes et de souligner la nécessité de travailler avec un poêle à granulés de bois dont le cycle de combustion est étanche. Un modèle mathématique est également développé pour prédire les performances du dernier prototype de conduit échangeur à triple paroi non isolé sur sa surface extérieure et sa validation est obtenue suite au bon accord entre les résultats calculés et ceux mesurés lors des essais. L’ensemble du système combiné est ensuite installé dans deux habitations à basse consommation d’énergie situées près de Poitiers. L’exploitation des températures et des consommations recueillies pendant la première saison de chauffe montre la bonne tenue du système combiné, ses limites, ainsi que ses conditions d’appropriation par les occupants, dont le comportement apparaît jouer un rôle prédominant dans la réduction des consommations énergétiques. / This work is devoted to the study and development of an innovative wood-based air-heating system for energy-efficient dwellings, which are expected to become the building reference in France from 2015 onwards. As these kinds of homes are highly insulated and particularly airtight, heating requirements are very low and may be covered by a renewable energy source, such as wood energy. In addition, efficient ventilation is absolutely required to ensure indoor air quality and may even sometimes be use as the only way to provide heat into the various rooms of the house. In this context, the system presented in this study aims to combine advantages of a low power wood-burning appliance, as a wood-pellet stove, and those of a mechanical ventilation heat-recovery unit, thanks to a heat exchanger integrated into the chimney of the pellet stove and connected to the ventilation air supply network. Developed in partnership with POUJOULAT, a metallic chimneys manufacturer, this new heat exchanger recovers a part of the heat from flue gases and enables to warm up the fresh air distributed in each living zone of the house, even the most remote of the wood heating device. After defining the best coupling configuration to ensure the proper behaviour of the system, as well as both safety and comfort of the occupants, performances of several heat exchanger prototypes are characterized experimentally. The results from tests in laboratory are then used to guide prototypes development and they highlight the need to work with a room-sealed wood-pellet stove. Moreover, a mathematical model is developed to predict the performances of the latest prototype of triple concentric tube heat exchanger with no insulation at the outer surface. Then, the model validation is obtained following the good agreement between calculated results and those measured during the laboratory tests. The combined system is then installed in two energy-efficient dwellings near Poitiers. Operating temperatures and energy consumptions collected during the first heating season show the good reliability of the combined system, its limitations and its conditions of acceptance by the occupants, whose behaviour is pointed out as a major factor in reducing energy consumptions.

Dans cette thèse, nous nous intéressons à certains aspects concernant les phénomènes hadroniques à basse énergie sous 1 GeV, en dessous de laquelle la symétrie chirale de la Chromodynamique Quantique (QCD) est spontanément brisée. En dessous de cette échelle d'énergie, le spectre de QCD se réduit à un octet de mésons légers pseudo-scalaires (π, K and η). Mais à cause du confinement, QCD sous 1 GeV devient hautement non perturbative – il n'est donc plus possible de décrire à basse énergie la dynamique de ces mésons en termes de gluons et de quarks (ici seuls les quarks légers u, d et s sont concernés). Deux alternatives principales à cet obstacle majeur existent néanmoins: la QCD sur réseau ainsi que les Théories Effectives des Champs. La QCD sur réseau consiste à calculer de manière numériques les diverses observables hadroniques, alors que les théories effectives permettent de nouveau une approche analytique (et perturbative) adaptée à une échelle d'énergie donnée. Dans le cas de QCD à basse énergie, c'est la Théorie Chirale des Perturbations (ChiPT) qui joue le rôle de théorie effective. Cette théorie peut être construite à partir de deux saveurs de quarks légers (u et s) ou trois (u,d, et s). Il est alors possible d'utiliser certains résultats de calculs sur réseau (ainsi que certains résultats expérimentaux) afin d'extraire des valeurs numériques pour les divers paramètres libres que contient la théorie chirale. Il fut néanmoins observé que le développement en séries chirales de quelques observables hadroniques sont numériquement “malades” dans le cadre de la théorie à trois saveurs. En effet, des travaux antérieurs montrent qu'il pourrait exister une possible compétition numérique entre l'Ordre Dominant (LO) et l'Ordre Sous-Dominant (NLO): en place de la hiérarchie usuelle LO>>NLO, l'équivalence LO~NLO prévalerait. La partie principale de la thèse consiste ainsi à la description et l'utilisation d'une version alternative de ChiPT, nommée Théorie Chirale des Perturbations Ressommée (ReChiPT ). Quelques observables hadroniques de basse energie sont calculées puis étudiées dans ce cadre “ressommé”, puis nous procédons à l'ajustement de certaines données de QCD sur réseau obtenues par des simulations à 2+1 quarks dynamiques sur ces observables exprimées en ReChiPT: les constantes de désintégrations et les masses de l'octet (π, K, η), ainsi que les facteurs de forme Kl3. Nous testons ensuite la validité de notre assertion concernant la possible compétition numérique observée dans les séries chirales. Enfin, dans la dernière partie, nous discutons plusieurs aspects analytiques et numériques concernant certaines quantités topologiques liées de manière intrinsèque à la très complexe structure du vide de QCD, dans le cadre de ChiPT (ressommé), et nous confrontons de nouveau cette étude à des données réseau 2+1. / In this thesis, we focus on some aspects concerning hadronic phenomena at low energy, below 1 GeV, under which the spontaneous breaking of chiral symmetry takes place. Under this scale, the spectrum of Quantum Chromodynamics reduces to an octet of light pseudo-scalar mesons (π, K and η). But because of the confinement property, QCD under 1 GeV is highly non-perturbative, it is thus not possible to describe at low energy the dynamics of these mesons in terms of gluons and quarks (in that case the three light quarks u,d, and s). Two main alternatives exist to circumvent this major obstacle: Lattice QCD and Effective Field Theories. Lattice QCD is concerned with the numerical computations of various hadronic observables, while Effective Field Theories correspond to analytical frameworks adapted to a particular energy scale. In the case of QCD at low energy, this role is devoted to Chiral Perturbation Theory (ChiPT). This theory can be built either from two quark flavours (u and d), or three (u,d, and s). Using the numerical results from Lattice QCD, it is possible to obtain numerical values for the unknown parameters that ChPT contains. It was however observed that the series expansions of hadronic observables stemming from ChiPT calculations do not “behave well” numerically in the three-flavour case. Indeed, previous works shown that there could exists at the numerical level a competition between the Leading and the Next-to- Leading order (LO and NLO); i.e., instead of the usually expected hierarchy LO>>NLO, one would have LO~NLO. The main part of the thesis work consists in the description and the use of a modified version of ChiPT allowing this numerical competition in the chiral series that was called “Resummed ChiPT”. Within this “Resummed” framework, we proceed to fitting data from 2+1 lattice calculations to hadronic observables computed in ChiPT: decay constants and masses of π, K and η, and Kl3 form factors, and check the consistency of our claim about the numerical competition in ChiPT expansions. In the last part, we discuss topological quantities that are intrinsically tied to the very complex structure of the QCD vacuum, in the (resummed) ChiPT framework and in the light of 2+1 lattice data, in their analytical and numerical aspects.

The project documentation, processed in the framework of the diploma thesis, solves the new building of the administrative building of the building company in the village Lukov u Moravských Budějovic. The building is made of traditional brick technology therm tl. 50 cm, without insulation, ceilings are reinforced concrete, flat roof, vegetation. Vegetation is also part of the facade of the building, which at the same time serves as a root cleaner. The philosophy of the whole design is to create a high-quality working environment for building company employees, a pleasant environment for customers and to best solve the environmental footprint of the building. The building is designed as a modern office building, with space for leisure activities of staff and their visits, taking into account the responsible approach to the development industrial site and the surrounding nature. The building efficiently manages potable, rain and wastewater, the envelope of the building, and the individual structures are designed to make the entire building as energy-consuming as possible, and do not pump irreparably by nature its natural resources in a larger quantity than necessary.