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Wireless implantable load monitoring system for scoliosis surgeryZbinden, Daniel Unknown Date
No description available.
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Wireless implantable load monitoring system for scoliosis surgeryZbinden, Daniel 06 1900 (has links)
Surgical correction of scoliosis is a complicated mechanical process. Understanding the loads applied to the spine and providing immediate feedback to surgeons during scoliosis surgery will prevent overloading, improve surgical outcome and patient safety. Long-term development of residual forces in the spinal instrument after surgery with the continual curvature changes over time has been unknown. The goal of this research work was to develop a wireless implantable sensor platform to investigate the loads during and after surgery. This thesis describes research leading to the design of a sensor platform that uses both 403 MHz and 2.45 GHz for wireless communication, and reports the resolution and accuracy of the built-in temperature sensor, the A/D accuracy of the sensing platform, the power consumption at different operation modes, the range of the wireless communication and the discharge characteristics of a potential capacitive power module. / Biomedical Engineering
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Applications of Miniaturized Ultrasound Powered Wireless Nerve Stimulators for Pain ManagementJanuary 2014 (has links)
abstract: Peripheral Vascular Disease (PVD) is a debilitating chronic disease of the lower extremities particularly affecting older adults and diabetics. It results in reduction of the blood flow to peripheral tissue and sometimes causing tissue damage such that PVD patients suffer from pain in the lower legs, thigh and buttocks after activities. Electrical neurostimulation based on the "Gate Theory of Pain" is a known to way to reduce pain but current devices to do this are bulky and not well suited to implantation in peripheral tissues. There is also an increased risk associated with surgery which limits the use of these devices. This research has designed and constructed wireless ultrasound powered microstimulators that are much smaller and injectable and so involve less implantation trauma. These devices are small enough to fit through an 18 gauge syringe needle increasing their potential for clinical use. These piezoelectric microdevices convert mechanical energy into electrical energy that then is used to block pain. The design and performance of these miniaturized devices was modeled by computer while constructed devices were evaluated in animal experiments. The devices are capable of producing 500ms pulses with an intensity of 2 mA into a 2 kilo-ohms load. Using the rat as an animal model, a series of experiments were conducted to evaluate the in-vivo performance of the devices. / Dissertation/Thesis / Muscle Twitching Excited by the Implanted Ultrasound Powered Device / Rat Hindlimb Withdraw Reflex / Masters Thesis Bioengineering 2014
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Investigation into the Hybrid Production of a Superelastic Shape Memory Alloy with Additively Manufactured Structures for Medical ImplantsHamann, Isabell, Gebhardt, Felix, Eisenhut, Manuel, Koch, Peter, Thielsch, Juliane, Rotsch, Christin, Drossel, Welf-Guntram, Heyde, Christoph-Eckhard, Leimert, Mario 05 May 2023 (has links)
The demographic change in and the higher incidence of degenerative bone disease have resulted in an increase in the number of patients with osteoporotic bone tissue causing. amongst other issues, implant loosening. Revision surgery to treat and correct the loosenings should be avoided, because of the additional patient stress and high treatment costs. Shape memory alloys (SMA) can help to increase the anchorage stability of implants due to their superelastic behavior. The present study investigates the potential of hybridizing NiTi SMA sheets with additively manufactured Ti6Al4V anchoring structures using laser powder bed fusion (LPBF) technology to functionalize a pedicle screw. Different scanning strategies are evaluated, aiming for minimized warpage of the NiTi SMA sheet. For biomechanical tests, functional samples were manufactured. A good connection between the additively manufactured Ti6Al4V anchoring structures and NiTi SMA substrate could be observed though crack formation occurring at the transition area between the two materials. These cracks do not propagate during biomechanical testing, nor do they lead to flaking structures. In summary, the hybrid manufacturing of a NiTi SMA substrate with additively manufactured Ti6Al4V structures is suitable for medical implants.
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Implantable Antennas For Wireless Data Telemetry: Design, Simulation, And Measurement TechniquesKaracolak, Tutku 11 December 2009 (has links)
Recent advances in electrical engineering have let the realization of small size electrical systems for in-body applications. Today’s hybrid implantable systems combine radio frequency and biosensor technologies. The biosensors are intended for wireless medical monitoring of the physiological parameters such as glucose, pressure, temperature etc. Enabling wireless communication with these biosensors is vital to allow continuous monitoring of the patients over a distance via radio frequency (RF) technology. Because the implantable antennas provide communication between the implanted device and the external environment, their efficient design is vital for overall system reliability. However, antenna design for implantable RF systems is a quite challenging problem due to antenna miniaturization, biocompatibility with the body’s physiology, high losses in the tissue, impedance matching, and low-power requirements. This dissertation presents design and measurement techniques of implantable antennas for medical wireless telemetry. A robust stochastic evolutionary optimization method, particle swarm optimization (PSO), is combined with an in-house finite-element boundary-integral (FE-BI) electromagnetic simulation code to design optimum implantable antennas using topology optimization. The antenna geometric parameters are optimized by PSO, and a fitness function is computed by FE-BI simulations to evaluate the performance of each candidate solution. For validating the robustness of the algorithm, in-vitro and in-vivo measurement techniques are also introduced. To illustrate this design methodology, two implantable antennas for wireless telemetry applications are considered. First, a small-size dual medical implant communications service (MICS) (402 MHz – 405 MHz) and industrial, scientific, and medical (ISM) (2.4 GHz – 2.48 GHz) band implantable antenna for human body is designed, followed by a dual band implantable antenna operating also in MICS and ISM bands for animal studies. In order to test the designed antennas in-vitro, materials mimicking the electrical properties of human and rat skins are developed. The optimized antennas are fabricated and measured in the materials. Moreover, the second antenna is in-vivo tested to observe the effects of the live tissue on the antenna performance. Simulation and measurement results regarding antenna parameters of the designed antennas such as return loss and radiation pattern are given and discussed in detail. The development details of the tissue-mimicking materials are also presented.
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Low-Power RF Front-End Design for Wireless Body Area NetworksKim, Jeong Ki 01 July 2011 (has links)
Wireless body area networks (WBANs) have tremendous potential to benefit from wireless communication technology and are expected to make sweeping changes in the future human health care and medical fields. While the prospects for WBAN products are high, meeting required device performance with a meager amount of power consumption poses significant design challenges. In order to address these issues, IEEE has recently developed a draft of IEEE 802.15.6 standard dedicated to low bit-rate short-range wireless communications on, in, or around the human body. Commercially available SoC (System-on-Chip) devices targeted for WBAN applications typically embed proprietary wireless transceivers. However, those devices usually do not meet the quality of service (QoS), low power, and/or noninterference necessary for WBAN applications, nor meet the IEEE standard specifications. This dissertation presents a design of low-power RF front-end conforming to the IEEE standard in Medical Communication Service (MICS) band of 402-405 MHz.
First, we investigated IEEE 802.15.6 PHY specifications for narrow band WBAN applications. System performance analysis and simulation for an AWGN (additive white Gaussian noise) channel was conducted to obtain the BER (bit error rate) and the PER (packet error rate) as the figure of merit. Based on the system performance study, the link budget was derived as a groundwork for our RF front-end design. Next, we examined candidate RF front-end architectures suitable for MICS applications. Based on our study, we proposed to adopt a direct conversion transmitter and a low-IF receiver architecture for the RF front-end. An asynchronous wake-up receiver was also proposed, which is composed of a carrier sensing circuit and a serial code detector. Third, we proposed and implemented low-power building blocks of the proposed RF front-end. Two quadrature signal generation techniques were proposed and implemented for generation of quadrature frequency sources. The two quadrature voltage controlled oscillators (QVCOs) were designed using our proposed current-reuse VCO with two damping resistors. A stacked LNA and a down-conversion mixer were proposed for low supply and low power operation for the receiver front-end. A driver amplifier and an up-conversion mixer for the transmitter front-end were implemented. The proposed driver amplifier uses cascaded PMOS transistors to minimize the Miller effect and enhance the input/output isolation. The up-conversion mixer is based on a Gilbert cell with resistive loads. Simulation results and performance comparisons for each designed building block are presented. Finally, we present a case study on a direct VCO modulation transmitter and a super-regenerative receiver, which can also be suitable for an MICS transceiver. Several crucial building blocks including a digitally-controlled oscillator (DCO) and quench signal generators are proposed and implemented with a small number of external components. / Ph. D.
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Low Power Merged LNA and Mixer Design for Medical Implant Communication ServicesJeong, Jihoon 02 April 2012 (has links)
The FCC allocated the spectrum of 402-405 MHz for MICS (Medical Implant Communication Services) applications in 1999. The regulations for MICS band apply to devices that support the diagnostic and/or therapeutic functions associated with implanted medical electronics. The implanted devices aid organs and control body functions of patients to support specific treatments, and monitor patients continuously so that necessary action can be taken in advance to avoid serious conditions. To enable to use MICS applications, several requirements must be satisfied. An implanted wireless device should have a small size, consume ultra-low power, and achieve the date rate of at least 200 kbps within 2 m distance. The major challenge is to realize ultra-low power devices. Thus the low-power design of the RF circuit is crucial for MICS applications as the power consumption of the wireless devices is mostly contributed by RF circuits.
This thesis investigates low-power design of an LNA and a down-conversion mixer of a receiver for MICS applications. The key idea is to stack an LNA and a mixer, while the LNA operates in the normal super-threshold region and the mixer in the sub-threshold region. In addition, a gm-boosting technique with a capacitor cross-coupled at the LNA input stage is also adopted to achieve a low noise figure (NF) and high linearity, which is critical to the overall performance of the receiver. The mixer operating in the sub-threshold region significantly reduces power dissipation and relaxes the voltage headroom without sacrificing the LNA performance. The relaxed voltage headroom enables stack of the LNA and the mixer with a low supply voltage of 1.2 V. The proposed circuit is designed in 0.18 μm RF CMOS technology. The merged LNA and mixer consumes only 1.83 mW, and achieves 21.6 dB power gain. The NF of the block is 3.55 dB at 1 MHz IF, and the IIP3 is -6.08 dBm. / Master of Science
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Design of Ultra-Low-Power Analog-to-Digital ConvertersZhang, Dai January 2012 (has links)
Power consumption is one of the main design constraints in today’s integrated circuits. For systems powered by small non-rechargeable batteries over their entire lifetime, such as medical implant devices, ultra-low power consumption is paramount. In these systems, analog-to-digital converters (ADCs) are key components as the interface between the analog world and the digital domain. This thesis addresses the design challenges, strategies, as well as circuit techniques of ultra-low-power ADCs for medical implant devices. Medical implant devices, such as pacemakers and cardiac defibrillators, typically requirelow-speed, medium-resolution ADCs. The successive approximation register (SAR) ADC exhibits significantly high energy efficiency compared to other prevalent ADC architectures due to its good tradeoffs among power consumption, conversion accuracy, and design complexity. To design an energy-efficient SAR ADC, an understanding of its error sources as well as its power consumption bounds is essential. This thesis analyzes the power consumption bounds of SAR ADC: 1) at low resolution, the power consumption is bounded by digital switching power; 2) at medium-to-high resolution, the power consumption is bounded by thermal noise if digital assisted techniques are used to alleviate mismatch issues; otherwise it is bounded by capacitor mismatch. Conversion of the low frequency bioelectric signals does not require high speed, but ultra-low-power operation. This combined with the required conversion accuracy makes the design of such ADCs a major challenge. It is not straightforward to effectively reduce the unnecessary speed for lower power consumption using inherently fast components in advanced CMOS technologies. Moreover, the leakage current degrades the sampling accuracy during the long conversion time, and the leakage power consumption contributes to a significant portion of the total power consumption. Two SAR ADCs have been implemented in this thesis. The first ADC, implemented in a 0.13-µm CMOS process, achieves 9.1 ENOB with 53-nW power consumption at 1 kS/s. The second ADC, implemented in a 65-nm CMOS process, achieves the same resolution at 1 kS/s with a substantial (94%) improvement in power consumption, resulting in 3-nW total power consumption. Our work demonstrates that the ultra-low-power operation necessitates maximum simplicity in the ADC architecture.
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Antenna Implants and Feasibility of Performance Limitations : AStudy of Radiation Efficiency on Electrically Small Antenna Implants with Finite Conductivity and Size / Antennimplantat och rimlighetsbedömning av dess prestandabegränsningar : En studie gällande effektivitet för elektriskt små antennimplant av realistisk konduktivitet och storlekAlgarp, Erik January 2022 (has links)
Antenna implants are used to establish a telemetry link to enable wireless data transfer, suitable for telemedicine and other medical applications. Inbody environments with water-based tissues lead to severe power absorption, making signal strength and radiation efficiency challenging yet central performance aspects of antenna implants. Fundamental performance limits exist regarding radiation efficiency; however, these limits consider theoretically ideal Hertzian dipoles. A semi-analytical model is used to evaluate the feasibility of previously determined fundamental bounds and the optimal dipole solution, both with respect to physical necessities of finite material conductivity and antenna size. This study uses a spherical model to represent a simplified in-body environment with various phantom compositions. Furthermore, the study focuses on implants operating within the Medical Implant Communication System (MICS) frequency band, but models and methods are not restricted to the considered frequency. The work contributes to the field of implantable antennas in several aspects; evaluating the feasibility of fundamental bounds, establishing more realistic performance limits, and determining the optimal dipole solution with respect to radiation efficiency. Other findings are presented in related areas, particularly concerning conductor loss and evaluation of the impedance for antennas inside a high-loss phantom. Moreover, the work presents a suggested method to measure electrically small magnetic dipole antennas. Methods and models are documented in a substantial theoretical derivation, and findings are verified using independent methods. Neglecting necessary antenna aspects like finite size and conductivity can lead to faulty conclusions on implant performance. Providing a more realistic performance target helps predict the performance of realistic antenna designs. Ultimately, increased knowledge of implanted antennas simplifies the design process to achieve high-performance implants. / Antennimplant används för att etablera en telemetrilänk som möjliggör trådlös dataöverföring, exempelvis användbart inom telemedicin och andra medicinska tillämpningar. Vattenbaserade kroppsmiljöer resulterar i kraftig absorption, vilket implicerar att signalstyrka samt strålningseffektivit blir utmanande men även centrala prestanda egenskaper för antennimplnatat. Det existerar fundamentala prestandabegränsningar för strålningseffektivitet, men dessa gränser är etablerade med hänsyn till teoretiskt ideala elementära dipoler. En semi-analytisk modell används för att utvärdera rimligheten av tidigare begränsningar samt den optimala dipolen, bägge med hänsyn till nödvändiga aspekter som ändlig konduktivitet och antennstorlek. Denna studie använder en sfärisk modell för att representera en simplifierad kroppslig miljö med olika vävnadskompositioner. Studien fokuserar på antennimplantat inom frekvensbandet dedikerat för Medical Implant Communication System (MICS) enheter, men modeller och metoder är typiskt inte begränsade inom omnämnt band. Arbetet bidrar till området för implanterbara antenner i flera aspekter; att utvärdera rimligheten av fundamentala gränser, fastställa mer realistiska prestandagränser samt bestämma den optimala dipolen med avseende på strålningseffektivitet. Andra resultat presenteras inom relaterade aspekter som metallförlust och utvärdering av en antenns last eller ingångs impedans inuti sfäriska och kroppsliga miljöer. Dessutom presenteras en metod för att mäta elektriskt små magnetiska dipoler. Metoder och modeller är dokumenterade eller demonstrerade via härledning, och centrala resultat har verifieras med oberoende metoder. Att förbise nödvändiga aspekter som ändlig storlek och konduktivitet kan leda till felaktiga slutsatser gällande prestanda. Däremot, att fastställa en mer realistisk gräns bidrar till att förutsäga prestandan i realistiska tillämpningar. I slutändan så resulterar ökad kunskap i en simplifierad designprocess som underlättar i strävan till att uppnå högpresterande antennimplantat.
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Méthode de discrétisation adaptée à une logique événementielle pour l'utra-faible consommation : application à la reconnaissance de signaux physiologiques / Discretization method adapted to an event-logic architecture for ultra-low power consumption : a physiological pattern recognition applicationLe Pelleter, Tugdual 13 May 2015 (has links)
Les systèmes embarqués mobiles font partis intégrante de notre quotidien. Afin de les rendre plus adaptésaux usages, ils ont été miniaturisés et leur autonomie a été augmentée, parfois de façon très considérable.Toutefois, les propositions d’amélioration butent désormais sur les possibilités de la technologie des circuitsintégrés. Pour aller plus loin, il faut donc envisager de repenser la chaîne de traitement du signal afin deréduire la consommation de ces dispositifs. Cette thèse développe une approche originale pour exploiterefficacement l’échantillonnage par traversée de niveaux d’une part et, d’autre part, associe cet échantillonnageà une logique évènementielle afin de réduire drastiquement la consommation d’énergie des systèmesintégrés autonomes. Une méthode de discrétisation adaptée à une application de reconnaissance de signauxphysiologiques, utilisée comme exemple dans cette thèse, y est présentée. Un premier prototype en logiqueévènementielle (asynchrone) sur circuit FPGA a permis de valider cette stratégie et de démontrer les bénéficesde cet échantillonnage dédié en termes de réduction de l’activité par rapport à un échantillonnage uniforme.Un second prototype en logique asynchrone et conçu en technologie CMOS AMS 0.35 μm a permis de validerpar simulation électrique un gain extrêmement important sur la consommation électrique du dispositif. / Our everyday life is highly dependent on mobile embedded systems. In order to make them suitable to differentapplications, they have underwent size reduction and lifetime extension. However, these improvementsare currently limited by the possibilities of the integrated circuits technologies. In order to push back theboundaries, it is necessary to reconsider the whole digital signal processing chain from scratch to sustain thepower consumption reduction in this kind of system. This work develops on the first hand a strategy thatsmartly uses the level-crossing sampling scheme and on the other combines this sampling method with eventlogicto highly reduce the power consumption in mobile embedded systems. A discretisation method adaptedto the recognition of physiological patterns application is described. A first event-logic (asynchronous) prototypeimplemented on FPGA proved the potential benefits that an adapted sampling scheme could offersto reduce activity compared to a uniform sampling scheme. Electrical simulations performed on a secondprototype, also designed in asynchronous logic, with CMOS AMS 0.35 μm technology, validated a high gainin power consumption.
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