Made available in DSpace on 2015-05-14T13:00:02Z (GMT). No. of bitstreams: 1 arquivototal.pdf: 1170808 bytes, checksum: 7b299ea2ca71a584be9ecd4dbd10364c (MD5) Previous issue date: 2014-02-14 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES / The irritable bowel syndrome (IBS) is defined as the presence of continuing or recurrent abdominal pain or discomfort and it is associated with altered bowel habit. Its pathophysiology involves the following aspects: genetic variables, changes in gut motility and visceral sensitivity, psychosocial factors, in addition to inflammatory and infectious processes. The treatment is based on dietary guidance and change in lifestyle. The use of drugs is indicated in symptomatic stages of IBS. The growing interest of patients for complementary and alternative medicine has been observed in recent years. Panax ginseng C.A. Meyer has been used for centuries in oriental medicine. Experimental studies have demonstrated the antinociceptive action of this herbal medicine on calcium and sodium channels, as well as on primary sensory neurons. The study aimed to: conduct phase II clinical trial with Panax ginseng CA Meyer in patients with IBS; contribute to the study of the pharmacological effects of Panax ginseng C.A. Meyer; evaluate the therapeutic efficacy of Panax ginseng C.A. Meyer in abdominal pain control in patients with IBS; and observe the adverse effects. Twenty-six patients were selected by means of the inclusion criteria for the study and they were divided into two groups. A clinical double-blind, randomized, prospective and experimental trial was conducted for eight weeks, comparing the action of dry extract of Panax ginseng (300 mg / day) with trimebutine (600 mg / day). Abdominal pain was assessed using the Likert scale. Patients were assessed at four visits and the results were analyzed using the Mann-Whitney and Friedman tests, with a significance level of p < 0.05. Twenty- four patients completed the study, being 87.50% female and mean age of 47.41 years. There was a relative homogeneity among patients with regard to sex, age and duration of symptoms. All patients, before beginning treatment with Panax ginseng and trimebutine, had negative scores for the Likert scale values. There was improvement in abdominal pain, through this scale, in patients who used Panax ginseng. This group started from a median basal of -5 to 2.5, 3 and 5 in the 1st, 4th and 8th weeks of treatment, respectively, with a statistically significant difference. Similar results were achieved in the group that used the trimebutine. The only adverse effect observed was the occurrence of headache in two patients (16.66%) in the group that used the herbal. Panax ginseng C.A. Meyer was effective in the control of abdominal pain in IBS patients, analogous to trimebutine, and may be used in future studies, with the prospect of a phase III clinical trial. / A síndrome do intestino irritável (SII) é definida pela presença de dor ou desconforto abdominal contínuo ou recorrente, estando associada com alterações do hábito intestinal. Sua fisiopatologia envolve os seguintes aspectos: variáveis genéticas, alterações da motilidade intestinal e da sensibilidade visceral, fatores psicossociais, além de processos inflamatórios e infecciosos. O tratamento é baseado em orientação dietética e na mudança do estilo de vida. O uso de fármacos é indicado nas fases sintomáticas da SII. Tem sido observado o crescente interesse dos pacientes pela medicina alternativa e complementar, nos últimos anos. O Panax ginseng C.A. Meyer é utilizado há séculos pela medicina oriental. Estudos experimentais demonstraram a ação antinociceptiva desse fitoterápico sobre os canais de cálcio e de sódio, assim como sobre os neurônios sensoriais primários. O estudo teve como objetivos: realizar ensaio clínico de fase II com o Panax ginseng C.A. Meyer em pacientes com SII; contribuir para o estudo dos efeitos farmacológicos do Panax ginseng C.A. Meyer; avaliar a eficácia terapêutica do Panax ginseng C.A. Meyer no controle da dor abdominal em pacientes com SII; observar os efeitos adversos. Foram selecionados vinte e seis pacientes, através de critérios de inclusão para a pesquisa, sendo divididos em dois grupos. Foi realizado um estudo clínico, duplo cego, randômico, prospectivo e experimental por oito semanas, comparando a ação do extrato seco do Panax ginseng (300 mg/dia) com a trimebutina (600 mg/dia). A dor abdominal foi avaliada através da escala de Likert. Os pacientes foram avaliados em quatro consultas e os resultados foram analisados através dos testes de Mann-Whitney e Friedman, com nível de significância quando p<0,05. Vinte e quatro pacientes concluíram o estudo, sendo 87,50% do sexo feminino e média de idade de 47,41 anos. Ocorreu uma relativa homogeneidade nos grupos de estudo no que se refere ao sexo, idade e duração dos sintomas. Todos os pacientes, antes do início dos tratamentos com Panax ginseng e trimebutina, apresentavam os valores negativos para os escores na escala de Likert. Houve melhora da dor abdominal, nos pacientes que utilizaram o Panax ginseng. Esse grupo partiu de uma mediana basal de -5 para 2,5, 3 e 5, na 1ª., 4ª. e 8ª. semanas de tratamento, respectivamente, com diferença estatisticamente significativa. O efeito adverso observado foi a ocorrência de cefaleia em dois pacientes (16,66%), no grupo que usou o fitoterápico. O Panax ginseng C.A. Meyer foi eficaz no controle da dor abdominal em pacientes com SII, de modo análogo à trimebutina, podendo ser utilizado em novos estudos, com a perspectiva de um ensaio clínico de fase III.

Ausstellung kuratiert von Johannes Schmidt / Die Ausstellungsbroschüren des „Projektraum am Weißen Hirsch. Galerie Grafikladen“ dokumentieren die Ausstellungstätigkeit eines nicht institutionellen Ausstellungsraumes in Dresden zwischen 2010 und 2016. Die Galerie widmete sich dem Werk zeitgenössischer junger Künstler, vorwiegend Meisterschüler und Absolventen, die in der Regel einen biografischen Bezug zu Dresden haben. Das Ausstellungskonzept war offen für die verschiedensten künstlerischen Ausdrucksformen – von Malerei über Fotografie bis zu performativen Ansätzen. Jährlich fanden vier bis fünf, von wechselnden Kuratoren entwickelte Ausstellungen statt. Im August 2016 eröffnete die vorerst letzte Ausstellung. / © bei den Rechteinhabern, Lizenz: Zugang frei – Rechte vorbehalten. Bitte beachten Sie unsere Hinweise zum Urheberrecht.

Denna uppsats ämnar att analysera genderswap tekniken i Stephenie Meyers bok Life and Death: Twilight Reimagined ur ett genusperspektiv. Uppsatsen förhåller sig till Lena Gemzöes bok Feminism där genusproblematiker diskuteras. Uppsatsen avser att jämföra Life and Death: Twilight Reimagined med original boken Twilight för att undersöka om det finns könsskillnader mellan huvudkaraktärerna Bella och Beau och hur genderswap påverkar detta. Analysen visar att via genderswap lyckas man framhäva skillnaderna mellan Bella och Beau i förhållande till våld, familjesfären och manliga privilegier. Via ett genderswap visar Meyer på hur den kvinnliga stereotypen fortfarande präglar Bella som kvinnlig karaktär och hur Beau som Bellas respektive manliga version framhäver existerande problematiker inom berättelsen. Jag argumenterar att analysen om genderswap driver till diskussion om hur könsroller gestaltas i Meyers två böcker och skapar utrymme för vidare diskussion inom ämnet.

This essay discusses the differences in depiction of vampires between Stephenie Meyer’s Twilight (2005) and Bram Stoker’s Dracula (1897). By using examples from the novels, the essay exemplifies how genre, narration, and readership affect the description of vampires within the two novels. The essay bases its discussion on genre on the premise that the vampire genre is in fact a genre to itself, but one with a broad variation. Furthermore, the essay briefly discusses the shift within the vampire genre, where vampires during the last centuries have gone from dangerous and scary to appealing and romantic. A connection is made between the shift within the vampire genre and Anne Rice’s vampire fiction. The discussion on genre shows how the romance, fantasy, and horror genres affect the depiction of vampires. / Denna uppsats diskuterar hur vampyrer i verken Twilight (Meyer, 2005) och Dracula (Stoker, 1897) skildras på olika sätt. Skillnader i beskrivningarna illustreras med hjälp av exempel från de båda böckerna och berör genre, berättarperspektiv och läsarkrets. Diskussionen i uppsatsen baseras på att vampyrgenren är en egen genre med många olika beskrivningar av vampyren. Uppsatsen berör även förändringen i genren och lyfter kort hur vampyren från början tolkas som farlig och skrämmande för att sedan framstå som attraktiv och romantisk. En koppling görs också mellan förändringen i vampyrgenren och Anne Rices vampyrnoveller. Vidare i diskussionen kring genre berörs även hur genrerna romantik, fantasy och skräck påverkar skildringen av vampyrerna i de nämnda verken.

ABSTRACT This dissertation argues that Bella Swan is a representation of Barbara Creed's monstrous-feminine which serves to reinforce ideologies that insist women are abject, inherently dangerous to men, and threatening to a patriarchal status quo. Through close-textual analysis of The Twilight Saga, I demonstrate how the monstrous-feminine frames the hysterical teenage body, hypersexuality, and eternal motherhood as simultaneously unacceptable and unavoidable. These negative women's stereotypes continue to persist in dominant popular culture, and this doublebind is overcome only by the impossible perfection of vampirism. The monstrous-feminine invites constructions of teenage bodies as unstable and unreliable, women's sexuality as dangerous and impure, and motherhood as a requirement for a complete identity. These constructions are particularly dangerous in Young Adult literature and particularly inspirational in fanfiction.

<p>This essay analyzes the difference between feminine and masculine narration in Stephanie Meyer's final novel in The Twilight Saga: Breaking Dawn. The methods used are Narratology, Reader-Response Criticism and Gender Theory. Breaking Dawn is divided into three different books and one of the main characters, Bella, is the narrator in the first and the last book, and the other main character, Jacob, is the narrator in the second book. Bella's and Jacob's narration styles are manifested in the title names and inside the text, and the analysis shows why Bella is a stereotypically female narrator and why Jacob is a stereotypically masculine narrator.</p>

<p>The project aim is to determine if good quality DNA can be extracted from barley, malt and hop, ingredients used in beer brewing. Good quality DNA is important in DNA fingerprinting techniques which can be used for identification of ingredients. The 3 methods tested are the cetyltrimethylammonium bromide (CTAB) method, QIAGEN DNeasy Plant Mini Kit and Meyer’s method as published in 1996 with QIAGEN DNeasy Plant Mini Kit in combination. To evaluate the DNA quality after extraction we used 3 different techniques:</p><p>(i) spectrophotometry to estimate purity by using the ratio A260/A280; (ii) agarose gel electrophoresis after DNA extraction to determine the success of the extraction and evaluate the amount of high molecular weight DNA and degradation; and (iii) the polymerase chain reaction with 4 different primer pairs, together with agarose gel electrophoresis, to determine if the extracted DNA could be used in downstream applications, see the effect of inhibitors and estimate the fragmentisation of the DNA. The results achieved using the above mentioned methods were then used to evaluate the success of each of the extraction methods in their function of extracting high quality DNA from barley, malt and hop as well as determining whether the treatment of the ingredients has an effect on the DNA quality.</p>

The project aim is to determine if good quality DNA can be extracted from barley, malt and hop, ingredients used in beer brewing. Good quality DNA is important in DNA fingerprinting techniques which can be used for identification of ingredients. The 3 methods tested are the cetyltrimethylammonium bromide (CTAB) method, QIAGEN DNeasy Plant Mini Kit and Meyer’s method as published in 1996 with QIAGEN DNeasy Plant Mini Kit in combination. To evaluate the DNA quality after extraction we used 3 different techniques: (i) spectrophotometry to estimate purity by using the ratio A260/A280; (ii) agarose gel electrophoresis after DNA extraction to determine the success of the extraction and evaluate the amount of high molecular weight DNA and degradation; and (iii) the polymerase chain reaction with 4 different primer pairs, together with agarose gel electrophoresis, to determine if the extracted DNA could be used in downstream applications, see the effect of inhibitors and estimate the fragmentisation of the DNA. The results achieved using the above mentioned methods were then used to evaluate the success of each of the extraction methods in their function of extracting high quality DNA from barley, malt and hop as well as determining whether the treatment of the ingredients has an effect on the DNA quality.

Diss. : Zürich : 1993. / Bibliogr. p. 159-169.

The focus of this thesis is how fanfiction, an underground subculture of web literature written about popular books, films, television shows, and comics, treats the original works it derives from. In this study I will examine the ways in which fans reshape the original stories of the works they write about, and the ways in which they do not, and speculate the reasons they have chosen to do so. This project examines fanfiction surrounding three young adult novels: Twilight, The Hunger Games, and Harry Potter. I examine each of these works and their respective fanfiction in order to highlight important themes in each work and problems inherent in each story to account for the changes fanfiction writers make in their literature. I have chosen one overarching theme in the fanfiction in each fandom and will explore why fanfiction authors have overwhelmingly chosen to change the source material to suit that theme.