• Refine Query
  • Source
  • Publication year
  • to
  • Language
  • 18
  • 13
  • 3
  • 3
  • 2
  • 1
  • 1
  • Tagged with
  • 52
  • 52
  • 12
  • 12
  • 10
  • 10
  • 8
  • 7
  • 7
  • 6
  • 6
  • 6
  • 6
  • 6
  • 5
  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
41

General Motor Function Assessment and Perceptions of Life Satisfaction during and after Geriatric Rehabilitation

Åberg, Anna Cristina January 2003 (has links)
<p>Two main goals of geriatric rehabilitation are to re-establish ability for physical function in order to facilitate independence in activities of daily living (ADL), and to promote an optimal degree of well-being, i.e. life satisfaction, in the individual. In this research a new scale, the General Motor Function assessment scale (GMF), was developed and evaluated. Subsequently, factors perceived as important for the life satisfaction of people undergoing geriatric rehabilitation were investigated. </p><p>The GMF includes both mobility and upper limb functions and comprises three subscales covering different aspects of functioning, namely performance-related Dependence, Pain and Insecurity. The clinical practicality of the GMF was evaluated by a field test. Its psychometric properties were analysed in both hospital and community-based settings of geriatric rehabilitation, using non-parametric statistical methods. The results indicated that the GMF is clinically adequate, possesses good reliability and is sensitive enough to demonstrate changes from pre- to post-intervention in different forms of geriatric rehabilitation. </p><p>For investigation of perceptions of life satisfaction, individual qualitative interviews were conducted with old (80+) care recipients and with their significant others, who had a helping relationship with them. The results revealed that habitual activity, independence and adaptation were generally considered to be important for the life satisfaction of the care recipients. Recalling of pleasant past memories in an effort to achieve current life satisfaction was a commonly used adaptive strategy among the care recipients. This strategy created a temporary sense of life satisfaction, with a potential for concealing dissatisfaction with conditions that might otherwise be correctable. From the perspective of the significant others, protection of the continuity of the care recipients’ self was seen as vital for the latter's life satisfaction, and was thus an underlying general purpose of the informal caregiving. </p>
42

General Motor Function Assessment and Perceptions of Life Satisfaction during and after Geriatric Rehabilitation

Åberg, Anna Cristina January 2003 (has links)
Two main goals of geriatric rehabilitation are to re-establish ability for physical function in order to facilitate independence in activities of daily living (ADL), and to promote an optimal degree of well-being, i.e. life satisfaction, in the individual. In this research a new scale, the General Motor Function assessment scale (GMF), was developed and evaluated. Subsequently, factors perceived as important for the life satisfaction of people undergoing geriatric rehabilitation were investigated. The GMF includes both mobility and upper limb functions and comprises three subscales covering different aspects of functioning, namely performance-related Dependence, Pain and Insecurity. The clinical practicality of the GMF was evaluated by a field test. Its psychometric properties were analysed in both hospital and community-based settings of geriatric rehabilitation, using non-parametric statistical methods. The results indicated that the GMF is clinically adequate, possesses good reliability and is sensitive enough to demonstrate changes from pre- to post-intervention in different forms of geriatric rehabilitation. For investigation of perceptions of life satisfaction, individual qualitative interviews were conducted with old (80+) care recipients and with their significant others, who had a helping relationship with them. The results revealed that habitual activity, independence and adaptation were generally considered to be important for the life satisfaction of the care recipients. Recalling of pleasant past memories in an effort to achieve current life satisfaction was a commonly used adaptive strategy among the care recipients. This strategy created a temporary sense of life satisfaction, with a potential for concealing dissatisfaction with conditions that might otherwise be correctable. From the perspective of the significant others, protection of the continuity of the care recipients’ self was seen as vital for the latter's life satisfaction, and was thus an underlying general purpose of the informal caregiving.
43

The Application of the Charlop-Atwell Scale of Motor Coordination to Children With Autism: An Objective and Subjective Measure of Gross Motor Functioning

Colton, Reny A 01 January 2013 (has links)
Recent research has investigated the prevalence of gross motor deficits in children diagnosed with Austim Spectrum Disorder (ASD), however these studies typically utilize the Bruininks-Oserestsky Test of Motor Proficiency, the Movement Assessment Battery for Children, the Peabody Developmental Motor Scales, or the Test of Gross Motor Development for assessment. These scales are expensive, require specialized equipment, are difficult to administer, and contain numerous test items that lead to long test administration times. The current research applied the Charlop-Atwell Scale of Motor Coordination to measure gross motor function deficits in children with autism and compared the data against scores from neurotypical children to determine the degree of delay of motor development. The Charlop-Atwell scale proved to be an effective measure of motor deficits and the study had high interobservor reliability. Children with ASD scored significantly lower than neurotypical children half their age on the objective subtest and total scale score. Looking at scores on separated test items, individual motor deficits were identified and results can be referred to an occupational or physical therapist for remedial treatment program development.
44

Efeitos do treino de marcha em esteira em crianças com paralisia cerebral / Effect of Treadmill Gait Training in Cerebral Palsy Children

Torre, Claudia Regina Monteiro Alcântara de 29 February 2012 (has links)
Made available in DSpace on 2016-06-02T20:19:18Z (GMT). No. of bitstreams: 1 4361.pdf: 2546261 bytes, checksum: 0ea61741466b8717008009085044d937 (MD5) Previous issue date: 2012-02-29 / The objective of this longitudinal study was to verify if the treadmill gait training improves the gross motor function in children with cerebral palsy (PC). This study evaluated 18 children with CP separated in two groups according with Gross Motor Function Classification System (GMFCS). To guarantee more homogeneity in the motor conditions two studies had been carried out: study 1 (levels I/II of the GMFCS) and 2 (levels III and IV of the GMFCS). Study 1 was composed for nine children with average of age of nine years and four months (5,7-13,2 years), level I (3 children) and II (6 children) of the GMFCS and study 2 was composed also for nine children with average of age of nine years (4 - 15 years), level III (3 children) and IV (6 children). Studies 1 and 2 had been lead in three phases: baseline, intervention and retention. The intervention phase consisted of treadmill gait training held twice a week in sessions of 25 minutes for six consecutive weeks. At each stage, the participants were evaluated using the Gross Motor Function Measure (GMFM) and 10m Walk Test (WT). In the retention phase, a Satisfaction Questionnaire for parents / caregivers was applied. Study 2 also used Functional Mobility Scale (FMS) to verify the influence of the protocol in functional mobility. In the statistics analysis, the ANOVA was applied in the two studies, separately. ANOVA with repeated measures was applied (group X evaluation) to analyze the total sample of the participants of the two studies. Study 1 showed positive changes in the scores of the GMFM in six participants and the WT-10m in five participants for normal speed and six for fast speed. The ANOVA indicated that it did not have significant difference between the evaluations. The Questionnaire showed that seven parents/caretakers had observed that the children were walking more rectified and that they were changing the steps easily less tired and needed less help. Study 2 showed positive changes in the scores of the GMFM in seven participants and the WT-10m in seven participants for the normal speed and in six for the fast. The ANOVA showed that it did not have significant difference between the evaluations. The Questionnaire showed that all the parents /caretakers had told that their children had started to walk more rectified, eight had reported that they had become less tired to walk the same distance in its daily routine and five had found that they had walked with more easiness and they had needed less help. The ANOVA with repeated measures showed that group levels I/II presented higher scores of the GMFM (p=0,001) and WT-10m in normal speed (p=0,001) and fast (p=0,001). It had difference between the evaluations for the total scores of the GMFM (p=0,019), being that GMFM 2 superior to GMFM 1 (p=0,06). In relation to the WT-10m, only for the fast speed had difference between the evaluations (p=0,027), being that in the after-intervention the average was greater than in the baseline (p=0,027). The protocol showed to significant changes in the motor function of the children with CP levels I/II and III/IV of GMFCS when the two groups had been analyzed jointly for the two applied quantitative measurements. In the analysis of study 1 and 2 separately, we did not find significant statistical results, however performance improvement was evidenced for the most part of the participants of the two groups, suggesting trend the improvement. The treadmill gait training leads to improvement of the gross motor function in children with CP levels I, II, III and IV. / O objetivo deste estudo longitudinal foi verificar se o treino de marcha em esteira melhora a função motora grossa em crianças com paralisia cerebral (PC). Este estudo avaliou 18 crianças com PC sendo estas separadas em dois grupos de acordo com o nível do Gross Motor Function Classification System (GMFCS). Para garantir mais homogeneidade nas condições motoras foram realizados dois estudos: estudo 1 (níveis I e II do GMFCS) e 2 (níveis III e IV do GMFCS). O estudo 1 foi composto por nove crianças com média de idade de nove anos e quatro meses (5,7-13,2 anos), classificadas nos níveis I (3 crianças) e II (6 crianças) do GMFCS; e o estudo 2 foi composto também por nove crianças com média de idade de nove anos (4 - 15 anos), classificadas nos níveis III (3 crianças) e IV (6 crianças). Os estudos 1 e 2 foram conduzidos em três fases: linha de base, intervenção e retenção. A fase de intervenção consistiu do treino de marcha em esteira realizado duas vezes por semana em sessões de 25 minutos por seis semanas consecutivas. Em todas as fases, os participantes foram avaliados usando Gross Motor Function Measure (GMFM) e Teste de caminhada de 10- m (TC). Na fase de retenção, um Questionário de Satisfação para pais/cuidadores foi aplicado. O estudo 2 também utilizou a Functional Mobility Scale (FMS), escala de avaliação usada para verificar a influência do protocolo na mobilidade funcional. Na análise estatística, foi aplicada a ANOVA nos dois estudos, separadamente. Foi aplicada ANOVA com medidas repetidas (grupo X avaliação) para analisar a amostra total dos participantes dos dois estudos. O estudo 1 mostrou mudanças positivas nos escores do GMFM em seis participantes e no TC-10m em cinco participantes para velocidade normal e em seis para velocidade rápida. A ANOVA indicou que não houve diferença significativa entre as avaliações. O Questionário mostrou que sete pais/cuidadores observaram que as crianças estavam andando mais retificadas e que estavam trocando os passos com mais facilidade, se cansavam menos e precisavam de menos ajuda. O estudo 2 mostrou mudanças positivas nos escores do GMFM em sete participantes e no TC-10m em sete participantes para a velocidade normal e em seis para a rápida. A ANOVA mostrou que não houve diferença significativa entre as avaliações. O Questionário mostrou que todos os pais /cuidadores relataram que suas crianças começaram a andar mais retificadas, oito reportaram que elas tornaram-se menos cansadas para andar a mesma distância na sua rotina diária e cinco acharam que andaram com mais facilidade e precisaram de menos ajuda. A ANOVA com medidas repetidas mostrou que o grupo níveis I/II apresentou maiores escores do GMFM (p=0,001) e TC-10m em velocidade normal (p=0,001) e rápida (p=0,001). Houve diferença entre as avaliações para o escore total do GMFM (p=0,019), sendo que o GMFM 2 superior ao GMFM 1 (p=0,006). Em relação ao TC- 10m, somente para a velocidade rápida houve diferença entre as avaliações (p=0,027), sendo que na pós-intervenção a média foi maior que na linha de base (p=0,027). O protocolo mostrou mudanças significativas na função motora das crianças com PC de GMFCS níveis I/II e III/IV quando os dois grupos foram analisados conjuntamente para as duas mensurações quantitativas aplicadas. Na análise do estudo 1 e 2 separadamente, não encontramos resultados estatisticamente significativos, porém melhora de desempenho foi constatada na maior parte dos participantes dos dois grupos, sugerindo tendência a melhora. O treino de marcha em esteira favorece a melhora da função motora grossa em crianças com PC dos níveis I, II, III e IV.
45

Effet de la buspirone sur le réflexe-H chez la souris adulte décérébrée spinale

Develle, Yann 05 1900 (has links)
No description available.
46

Memória, ansiedade e função motora na prole de ratas com hipotireoidismo gestacional / Memory, anxiety and motor function in offspring of rats with gestational hypothyroidism

Menezes, Edênia da Cunha 03 September 2014 (has links)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / Maternal thyroid hormones (THs) are crucial for fetal development, especially to the central nervous system. Changes in maternal THs levels during pregnancy can result in many organic disorders over the life of the offspring. We aimed to investigate the impact of the lack of maternal THs during the pregnancy in the memory, anxiety and motor function in the offspring. Hypothyroidism was induced by ad libitum administration of 0.02% methimazole (MMI) in drinking water, from 9th day of pregnancy until delivery day. At 75 and 120 postnatal day (75 and 120 PND), the offspring (males) from MMI-treated dams (OMTD) and water-treated dams (OWTD) were subjected to different tests: i. spontaneous alternation (SAT), object recognition (OR), hole board (HB), free exploration paradigm (FEP), catalepsy (CT) and open field (OF). To evaluate short term memory we used SAT and OR. State and trait anxiety were evaluated by HB and FEP, respectively. The motor function was accessed by CT and OF. Statiscal test for homoscedasticity (Levene) and normality (Shapiro-Wilks) were applied. Data with normal distribution and homoscedastic were analyzed by unpaired one sample t-test. Non-normal and non-homoscedastic data were analyzed by non-parametric Mann Whitney test. When required, two-way ANOVA followed by Bonferroni post-hoc was used. Both, SAT and OR showed that OMTD had lower short term memory. In SAT, OMTD presented lower percentage of complete alternations compared to OWTD, at 75 and 120 PND, (p<0.001; p<0.01, respectively). At 75 and 120 PND, OMTD were not able to discriminate new and old objects (p=0.26; p=0.70) in OR test. OMTD spent less time exploring both objects, but only at 120 PND, regardless of the session (p<0.01). A decreased anxiety state was evidenced in OMTD by the increased number of head-dip on the HB test, both at 75 (p<0.05) and 120 PND (p<0.05), as well as by the increase in time spent in head-dip, only at 120 PND (p<0.01). Moreover, no changes were observed on the anxiety profile of OMTD subjected to FEP in both studied ages. We also observed an increase on the cataleptic behavior on OMTD, by the greater time spent in the apparatus bar, both at 75 (p<0.05) and 120 PND (p<0.01). The ambulation on OF didn´t differed between the groups. Thus, this study demonstrated, for the first time, that the lack of maternal THs during the pregnancy reduces the short-term memory, motor function and state anxiety of offspring of rats. The increased catatonic behavior in OMTD suggests loss of motivation and/or anhedonia. / Os hormônios tireoidianos (HTs) maternos são essenciais para o desenvolvimento orgânico do feto, sobretudo na maturação do sistema nervoso central. Alterações na concentração dos HTs maternos durante a gestação podem implicar no aparecimento de distúrbios orgânicos diversos ao longo da vida da prole. O objetivo do estudo foi investigar as repercussões da carência dos hormônios tireoidianos maternos durante a gestação na memória, ansiedade e função motora na prole de ratas. O hipotireoidismo foi induzido pela administração ad libitum de metimazol 0,02% na água de beber, do 9º dia de gestação até o dia do parto. Aos 75 e 120 dias pós-natal (75 e 120 DPN), machos das proles de mães hipotireoidianas (PMH) e eutireoidianas (PME) foram submetidos aos testes de alternação espontânea (TAE), reconhecimento de objetos (RO), placa perfurada (PP), paradigma da exploração livre (PEL), teste de catalepsia (TC) e campo aberto (CA). Para avaliar memória de curto prazo foram utilizados TAE e RO. Ansiedade estado e traço foram avaliadas respectivamente pelo teste de PP e pelo PEL. A função motora foi acessada pelo TC e CA. Os dados obtidos foram analisados por meio dos testes de homocedasticidade (Levene) e de normalidade (Shapiro-Wilks). Para dados com distribuição normal e homocedásticos foram realizados os testes t de Student não pareado e de uma amostra. Dados não normais ou não homocedásticos foram analisados pelo teste não paramétrico de Mann Whitney. Quando sob influência de dois fatores de variação, os dados foram analisados por ANOVA de duas vias, seguido do pós-teste de Bonferroni. O TAE e o RO mostraram que PMH têm comprometimento da memória de curto prazo. O TAE revelou que a PMH apresentou menor porcentagem de alternações completas quando comparada a PME, tanto aos 75 quanto aos 120 dias pós-natal (DPN), (p<0,001; p<0,01, respectivamente). Aos 75 e 120 DPN, a PMH não foi capaz de discriminar o objeto novo do antigo (p=0,26; p=0,70, respectivamente) no RO. Somente aos 120 DPN se observou menor tempo total de exploração de objetos na PMH, independente da sessão (p<0,01). Menor estado ansioso foi evidenciado na PMH pelo maior número de head-dip na PP, tanto aos 75 DPN (p < 0,05) como aos 120 DPN (p< 0,05), bem como pelo maior tempo de permanência no head-dip, somente aos 120 DPN (p< 0,01). Por outro lado, não foram identificadas mudanças no perfil ansioso da PMH submetidas ao PEL em nenhuma das idades estudadas. Aumento do comportamento de catalepsia foi observado na PMH, que apresentou maior o tempo de permanência na barra do aparato, tanto aos 75 DPN (p < 0,05) quanto aos 120 DPN (p< 0,01). A ambulação no CA não diferiu entre os grupos. Assim, este trabalho demonstrou, pela primeira vez, que a carência de HTs maternos durante gestação reduz a memória de curto prazo, a função motora e a ansiedade estado da prole de ratas. O aumento do comportamento de catatonia na PMH aventa ainda a possibilidade de perda de motivação e/ou anedonia.
47

Caracterização da gravidade motora e respiratória de pacientes com Distrofia Muscular de Duchenne / Motor and respiratory severity characterization of Duchenne Muscular Dystrophy patients

Luiz, Lívia Cocato, 1986- 05 September 2014 (has links)
Orientadores: José Dirceu Ribeiro, Anamarli Nucci / Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas / Made available in DSpace on 2018-08-25T06:16:29Z (GMT). No. of bitstreams: 1 Luiz_LiviaCocato_M.pdf: 3785934 bytes, checksum: 1710c66693a6b2ad73359d8f3b987905 (MD5) Previous issue date: 2014 / Resumo: Contextualização: A distrofia muscular de Duchenne (DMD) é a miopatia infantil mais comum, e sua progressão é causada pela perda de massa e força muscular. Os cuidados paliativos são extremamente influenciados pelas disfunções motoras e respiratórias. O objetivo do presente estudo foi caracterizar simultaneamente as disfunções motora e respiratória em pacientes com DMD. Métodos: Estudo transversal realizado em um hospital universitário terciário em uma população de 34 pacientes com DMD: 19 foram avaliados simultaneamente para disfunção motora [Medida da Função Motora (MFM) e Teste de Caminhada de 6 Minutos (TC6¿)] e respiratória [força muscular respiratória, pico de fluxo da tosse (PFT), espirometria e capnografia volumétrica (CapV)]. Resultados: Foi encontrada diferença estatística (p<0,05) na MFM para DMD deambuladores e não- deambuladores; no TC6¿ [DMD mostrou menor distância percorrida; maior frequência respiratória no repouso, frequência cardíaca (FC) no repouso e FC após 9 minutos em relação aos controles]; na espirometria [DMD mostrou menor capacidade vital forçada (CVF), volume expiratório forçado no primeiro segundo, fluxo expiratório forçado entre 25-75% da CVF, fluxo expiratório forçado máximo e maior índice de Tiffeneau que os controles]; e na CapV [DMD mostrou menor volume minuto alveolar, volume minuto, volume corrente alveolar, volume corrente total, volume espaço morto, volume de dióxido de carbono e volume expiratório que controles menores de 11 anos e também DMD mostrou maior FC que controles maiores de 11 anos]. Conclusões: Pacientes com DMD mostraram deterioração motora e respiratória independentemente da progressão da doença ou da condição da marcha. A MFM e o TC6¿ puderam demonstrar a variabilidade da disfunção motora. Entre as ferramentas para avaliação respiratória, a espirometria mostrou o comprometimento mais evidente, seguida do PFT. No entanto, não houve correlação entre a gravidade motora e respiratória nesta série / Abstract: Background: Duchenne muscular dystrophy (DMD) is the most common child myopathy, and its progression is caused by loss of muscle mass and strength. The palliative management is greatly influenced by motor and respiratory dysfunctions. The aim of the present study was to simultaneously characterize motor and respiratory dysfunctions in DMD. Methods: A cross-sectional study was performed in a tertiary university hospital in a cohort of 34 DMD patients¿; 19 were simultaneously evaluated for motor [Motor Function Measure (MFM) and 6-minute walk test (6MWT)] and respiratory evaluation [respiratory muscle strength, cough peak flow (CPF), spirometry and volumetric capnography (VCap)]. Results: Statistical difference (p<0.05) was found in MFM for ambulatory and non- ambulatory DMD; in 6MWT [DMD showed lower walked distance, higher rest respiratory rate, rest heart rate (HR) and HR after 9minutes than controls]; in spirometry [DMD showed lower vital forced capacity (VFC), forced expiratory volume in one second, forced expiratory flow between 25-75%VFC, maximum forced expiratory flow and higher Tiffeneau index than controls]; and in VCap [DMD showed lower alveolar ventilation per minute, ventilation per minute, tidal alveolar volume, tidal volume, airway dead space, carbon dioxide production and expiratory volume than controls younger than 11 years; and also DMD showed higher HR when compared to controls older than 11 years]. Conclusions: Patients with DMD showed motor and respiratory deterioration regardless disease progression or ambulatory status. The MFM and 6MWT could demonstrate the motor impairment variability. Among the respiratory tools used, the spirometry showed more evident compromise, followed by the CPF. Nevertheless, motor and respiratory severity did not correlate in this series / Mestrado / Saude da Criança e do Adolescente / Mestra em Ciências
48

Caractérisation clinique et par la tomographie d’émission par positrons quantitative du trouble de l’acquisition de la coordination / Clinical and quantitative positron emission tomography characterization of lower case

Farmer, Marie January 2016 (has links)
Résumé : Le trouble de l’acquisition de la coordination (TAC), d’étiologie encore indéterminée, est une anomalie neurologique affectant environ 6% des enfants de l'âge scolaire. Le TAC se manifeste essentiellement par un déficit au niveau des exécutions motrices. Le présent travail de recherche comporte deux volets portant sur le TAC. Premièrement, une étude clinique sur 129 sujets âgés de 4 à 18 ans a permis de classifier les caractéristiques du TAC en sous-groupes cliniques. Trente-trois caractéristiques du TAC, les plus fréquemment rapportées dans la littérature, ont été recensées chez nos sujets. L'application d'évaluations statistiques a permis de faire ressortir trois classes essentielles. Le deuxième volet consistait à identifier les régions cérébrales impliquées dans une tâche motrice à l'aide de l'imagerie par la tomographie d'émission par positrons (TEP). Deux sujets avec TAC et deux sujets normaux ont été étudiés en deux séances d'imagerie TEP dont l'une au repos et l'autre en tapotant du pouce sur les doigts de la main gauche non-dominante. Les analyses du premier volet ont montré, entre autres, que le TAC touchait 3.17 garçons pour une fille, que tous les sujets étaient lents, que 47% des sujets étaient gauchers ou ambidextres alors que seulement 10% sont gauchers dans la population générale, que 26% avaient une dyspraxie verbale, et que 83% avaient été diagnostiqués anxieux. Les sujets ont été classés en trois sous-groupes: 1- maladroits et autres caractéristiques, sans problème de langage; 2- trouble de l’estime de soi et relation avec les pairs; 3- difficulté de langage. En imagerie, les structures cérébrales ont été classées selon leur captation du 18F-fluorodesoxyglucose (FDG) dans les hémisphères droit et gauche, avant et après l'activation, et en comparaison avec les sujets normaux. Trois types de structures cérébrales sont ressortis avec les statistiques: des structures activées, celles relativement non sollicitées et des structures désactivées. Il y avait plus de variations dans la captation du FDG chez les sujets avec TAC que chez les normaux. En conclusion, la caractérisation des sujets avec TAC par le diagnostic clinique et par l'imagerie peut procurer un plan de thérapie adéquat et ciblé étant donné que le TAC a un large spectre et pourrait coexister avec d'autres déficits cérébraux. / Abstract : Developmental Coordination Disorder (DCD) is a neurological abnormality affecting approximately 6% of children of school age. DCD is essentially manifested by deficit in motor executions. The present research aims two parts of DCD. First, a clinical study on 129 subjects aged 4 to 18 years old allowed to classify DCD characteristics (subtyping) in three classes. Thirty-three features of DCD, the most frequently reported in literature, have been identified in our subjects. The application of statistical clustering produced three essential classes. The second part was to identify the brain regions involved in a motor task using positron emission tomography (PET) imaging. Subjects with DCD and control subjects were studied in two PET imaging sessions at rest and then by tapping the thumb on each finger of the left non-dominant hand. The results showed, that DCD concerned 3.17 boys for one girl, all subjects were slow, 47% of the subjects were left-handed or ambidextrous while only 10% are left-handed in general population, 26% had a verbal dyspraxia, and 83% had been diagnosed with anxiety. Subjects were classified into three groups: 1- clumsy and other features without language problem; 2- self-esteem and peer relationships concern; 3- difficulty of spoken language. With PET imaging, the brain structures were classified according to their uptake of 18F-fluorodeoxyglucose (FDG) in the right and left hemispheres before and after activation, and compared with normal subjects. Three types of brain structures statistically emerged: activated structures, those relatively unsolicited and those disabled. There was more variation in uptake of FDG in patients with DCD than in control subjects. In conclusion, the characterization of subjects with DCD for clinical diagnostic and imaging can provide adequate and focused treatment plan since DCD has a broad spectrum and could coexist with other brain deficits.
49

Análise comparativa entre as escalas funcionais do membro superior WMFT e ARAT utilizadas na avaliação da terapia por contensão induzida em pacientes com AVC isquêmico / Comparative analysis between the upper extremity functional scales WMFT and ARAT user in evaluation of constraint-induced movement therapy in ischemic stroke patients

Assis, Rodrigo Deamo [UNIFESP] 30 July 2008 (has links) (PDF)
Made available in DSpace on 2015-07-22T20:49:20Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-07-30 / Introdução: A Terapia por Contensão Induzida (TCI) ou Constraint-induced Movement Therapy é uma intervenção que tem como objetivo a recuperação do membro superior afetado de pacientes hemiparéticos devido à lesão encefálica. É aplicada através de um tratamento intensivo durante duas semanas consecutivas, com seis horas diárias de exercícios e uso de uma tipóia, durante 90% do dia, no membro superior não-afetado. O ganho motor da TCI é validado através das escalas funcionais de avaliação do membro superior (EFAMS) Wolf Motor Function Test (WMFT) e Action Research Arm Test (ARAT). Objetivo: Realizar uma análise comparativa entre ambas as EFAMS. Métodos: As EFAMS foram aplicadas em quatro períodos distintos em 17 pacientes com o diagnóstico de acidente vascular cerebral isquêmico, que realizaram individualmente a TCI durante duas semanas com seis horas diárias de exercícios e após foi feito uma análise comparativa entre as EFAMS em relação ao tempo de aplicação, tempo de preparação da mesa, reprodutibilidade e análise fatorial. Resultados: Diminuição no escore da EFAMS WMFT e aumento no escore da EFAMS ARAT pós TCI, não houve variação significativa dos escores entre os períodos pré e pós TCI das EFAMS, diminuição do tempo de preparação da mesa e aplicação de ambas as EFAMS pós TCI e a análise fatorial detectou dois e três componentes qualitativos na EFAMS ARAT e WMFT, respectivamente. Conclusões: Ambas as EFAMS conseguem mensurar o ganho motor da TCI, com alta reprodutibilidade, sendo que o tempo de aplicação e preparação da mesa é menor na EFAMS ARAT e somente a EFAMS WMFT apresenta o componente qualitativo “lateralidade”. / The Constraint-induced Movement therapy (CIMT) is an intervention which main goal is the recuperation of affected upper extremity in hemiparetic patients with acquired encephalic lesion. Its protocol consists by an intensive treatment of two consecutive weeks with six hours of exercises and the wear of arm sling in non affected upper arm during 90% of daily activities. The motor improvement of CIMT is validity by the functional evaluation scales of upper extremity (FESUE) Wolf Motor Function Test (WMFT) and Action Research Arm Test (ARAT). Objective: Realize a comparative analysis between both scales. Methodology: The FESUE had been applied during four different times in 17 patients with diagnosis of ischemic stroke, who made individually the CIMT during two weeks and six hours of exercises and after made a comparative analysis between the FESUE by time for application, time for preparation of the table, reproducibility and factorial analysis. Results: Decreased in score of FESUE WMFT and increased in score of FESUE ARAT after CIMT, no significant variation in the score between before and after CIMT of the FESUE, decreased in time to preparation the table and application of FESUE in both scales and the factorial analysis showed two and three qualitative components in FESUE ARAT and WMFT, respectively. Conclusions: Both FESUE can measure the therapeutics gains of CIMT, with high reproducibility, but the time for application and preparation of the table are minor in FESUE ARAT and only the FESUE WMFT shows the qualitative component “laterality”. / TEDE / BV UNIFESP: Teses e dissertações
50

Neuromuscular Changes in Older Adults during the Lateral Step Task

Bejarano, Tatiana 12 November 2014 (has links)
Older adults may have trouble when performing activities of daily living due to decrease in physical strength and degradation of neuromotor and musculoskeletal function. Motor activation patterns during Lateral Step Down and Step Up from 4-inch and 8-inch step heights was assessed in younger (n=8, 24.4 years) and older adults (n=8, 58.9 years) using joint angle kinematics and electromyography of lower extremity muscles. Ground reaction forces were used to ascertain the loading, stabilization and unloading phases of the tasks. Older adults had an altered muscle activation sequence and significantly longer muscle bursts during loading for the tibialis anterior, gastrocnemius, vastus medialis, bicep femoris, gluteus medius and gluteus maximus muscles of the stationary leg. They also demonstrated a significantly larger swing time (579.1 ms vs. 444.8 ms) during the step down task for the moving leg. The novel data suggests presence of age-related differences in motor coordination during lateral stepping.

Page generated in 0.1309 seconds