[ES] Conocer las propiedades electromagnéticas de los tejidos biológicos con la mayor exactitud posible tiene una gran importancia en el diseño de un elevado número de aplicaciones biomédicas. El diseño de dispositivos médicos inalámbricos, antenas superficiales e intracorporales, evaluación de tasas de absorción electromagnética, técnicas de tratamiento y detección de cáncer como la hipertermia e imágenes médicas son ejemplos de aplicaciones que requieren esta información para su desarrollo. Debido a que el cáncer provoca modificaciones estructurales en las células que a su vez generan cambios en las propiedades electromagnéticas, es posible desarrollar aplicaciones de detección de cáncer que se basen en este hecho. Un objetivo potencial es el cáncer de colon (CRC), debido a que los tejidos de colon sospechosos son accesibles de forma más o menos sencilla durante procedimientos endoscópicos. Este tipo de cáncer es uno de los más extendidos, siendo responsable de aproximadamente el 10% de casos y muertes totales. Existe un gran número de factores de riesgo que pueden explicar la aparición de la enfermedad, aunque esencialmente la probabilidad se incrementa significativamente con el aumento de la edad de la población. Los programas de cribado sobre la población son críticos: si el cáncer se detecta en etapas tempranas, la probabilidad de sobrevivir se incrementa en gran medida, y además se reducen los costes asociados. Uno de los objetivos principales de esta tesis es proponer aplicaciones que ayuden en la detección de CRC durante la colonoscopia haciendo uso de las diferencias en las propiedades electromagnéticas. Aparte de mejoras en el diagnóstico, complementar la colonoscopia puede conllevar otros beneficios colaterales como una reducción en la carga de anatomía patológica. Para demostrar la viabilidad y el potencial desarrollo futuro de estas aplicaciones, en esta tesis se miden y se trata de encontrar diferencias entre las propiedades electromagnéticas de tejidos sanos, cancerosos y patológicos de colon humano. Las medidas han sido llevadas a cabo mediante la técnica del coaxial terminado en abierto. Con el propósito de incrementar la precisión del método, se ha evaluado el principio de funcionamiento y se ha mejorado el proceso de calibración. Dos fuentes de tejido de colon han sido analizadas en esta tesis: tejidos procedentes de colonoscopias (biopsias) y tejidos obtenidos a partir de procedimientos quirúrgicos. Aparte de tejido sano, se estudian las siguientes patologías: Adenocarcinomas (CRC), adenomas sin displasia, adenomas con bajo grado de displasia, adenomas con alto grado de displasia, hiperplasias y hamartomas. Debido a la alta variabilidad entre distintos sujetos, las propiedades electromagnéticas de los tejidos sospechosos de un paciente en concreto deben ser siempre comparadas con las propiedades de sus tejidos sanos, no evaluadas de forma independiente. El segundo gran objetivo de esta tesis es el desarrollo de una nueva base de datos de las propiedades electromagnéticas de tejidos biológicos medidas in vivo. Ahora mismo, las colecciones disponibles están limitadas en número de tejidos o frecuencias caracterizadas, obligando a los investigadores a escoger bases de datos más completas pero realizadas ex vivo. No obstante, usar este tipo de colecciones tienen fuentes de incertidumbre adicionales dado que las medidas están condicionadas por la deshidratación de los tejidos y la perdida de flujo sanguíneo. El desarrollo de esta nueva base de datos puede facilitar el diseño de aplicaciones que requieran conocer las propiedades electromagnéticas con alto grado de precisión. / [CA] Conéixer les propietats electromagnètiques dels teixits biològics amb la major exactitud possible té una gran importància en el disseny d'un gran nombre d'aplicacions biomèdiques. El disseny de dispositius metges sense fil, antenes superficials i intracorporales, l'avaluació de taxes d'absorció electromagnètica, tècniques de tractament i detecció de càncer com ara la hipertèrmia i imatges mediques són exemples d'aplicacions que requerixen esta informació. Com el càncer provoca modificacions estructurals en les cèl·lules que generen canvis en les propietats electromagnètiques, es possible desenrotllar aplicacions de detecció de càncer que es basen en este fet. Un objectiu potencial és el càncer de colon (CRC), pel fet que els teixits de colon sospitosos són accessibles de forma més o menys senzilla durant procediments endoscòpics. Este tipus de càncer és un dels més estesos, sent responsable d'aproximadament el 10% de casos i morts totals. N'hi ha un gran nombre de factors de risc que poden explicar l'aparició de la malaltia, encara que en resum la probabilitat s'incrementa significativament amb l'augment de l'edat de la població. Els programes de cribratge sobre la població són crítics. Si el càncer es detecta en etapes primerenques, la probabilitat de sobreviure s'incrementa en gran manera, i a més es reduïxen els costos associats. Un dels objectius principals d'esta tesi és proposar aplicacions que ajuden en la detecció de CRC durant la colonoscòpia fent ús de les diferències en les propietats electromagnètiques. A banda de millores en el diagnòstic, complementar la colonoscòpia pot comportar altres beneficis col·laterals com una reducció en la càrrega d'anatomia patològica. Per a demostrar la fiabilitat i el potencial desenrotllament d'aquestes aplicacions, en aquesta tesi es mesuren i es tracta de trobar diferències entre les propietats electromagnètiques de teixits sans, cancerosos i patològics de colon humà. Les mesures han sigut realitzades mitjançant la tècnica del coaxial acabat en obert. Amb el propòsit d'incrementar la precisió del mètode, s'ha avaluat el seu principi de funcionament i s'ha millorat el procés de calibratge. Dos fonts de teixit de colon s'han analitzat en aquesta tesi: teixits procedents de colonoscòpies (biòpsies) i teixits obtinguts a partir de procediments quirúrgics. Apart de teixit sà, s'estudien els següents teixits: Adenocarcinomes (CRC), adenomes sense displàsia, adenomes amb baix grau de displàsia, adenomes amb alt grau de displàsia, hiperplàsies y hamartomes. Degut a l'alta variabilitat entre diferents subjectes, les propietats electromagnètiques dels teixits sospitosos d'un pacient en particular han de ser comparades amb les propietats dels seus teixits sans, no avaluats independentment. El segon gran objectiu d'esta tesi és el desenrotllament d'una nova base de dades de les propietats electromagnètiques de teixits biològics mesurades in vivo. Ara mateix, les col·leccions disponibles estan limitades en nombre de teixits o freqüències caracteritzades, obligant els investigadors a triar bases de dades més completes però realitzades ex vivo. No obstant això, este tipus de col·leccions te fonts d'incertesa addicionals atés que les mesures estan condicionades per la deshidratació dels teixits i la pèrdua de flux sanguini. El desenrotllament d'esta nova base de dades pot facilitar el disseny d'aplicacions que requerisquen conéixer les propietats electromagnètiques amb alt grau de precisió. / [EN] Nowadays, a careful knowledge of the electromagnetic properties of biological tissues is required for developing a great number of applications. The development of wireless medical devices, the design of in-body and on-body antennas, specific absorption rate evaluations, cancer treatment techniques such as hyperthermia and detection techniques like medical imaging are some examples of applications that rely on these data. Since cancer causes modifications on the biological structure of cells that can lead in turn to changes in the electromagnetic properties of the tissues, it is possible to develop novel detection applications taking advantage of it. One potential target is colorectal cancer (CRC), as suspicious tissues can be accessed quite easily through colonoscopy procedures. This kind of cancer is one of the most spread kinds, being responsible of about 1 out of 10 new cancer cases and deaths. There are several risk factors currently related to the apprising of this cancer, although in essence the higher the age of the population, the higher the incidence of CRC. Screening programs are key for detecting and diagnosing cancer: if found at early stages, the probability of survival increases greatly, and the cost of the treatment can be reduced as well. One of the major objectives of this dissertation is proposing applications for detecting CRC that aid in the colonoscopy procedures by making use of the differences in electromagnetic properties. Aside from enhancement in the diagnosis of CRC, improving the colonoscopy procedure can lead to collateral benefits like a lowering of the burden of anatomical pathology unit. With the aim at demonstrating the feasibility and the potential future development of these applications, in the framework of this thesis the dielectric properties of healthy, cancerous and pathological human colon tissues are measured and compared in order to find electromagnetic differences. Measurements are carried out by means of an open-ended coaxial system. Its principle of operation has been revisited with the aim at maximizing the accuracy of the method, and the calibration procedure has been optimized serving the same purpose. Two main sources of colon tissue have been analyzed: samples from colonoscopy biopsies and samples from surgery resections. Besides healthy tissue, the following colon tissues have been characterized: Adenocarcinomas (CRC), adenomas without dysplasia, adenomas with low-grade dysplasia, adenomas with high-grade dysplasia, hyperplastic polyps and hamartomatous polyps. Given the variability that can appear among subjects, the electromagnetic properties of suspicious tissues from a particular patient have to be always compared with those of his healthy ones, not evaluated independently. The second major objective of this thesis involves the development of a new database of electromagnetic properties of biological tissues obtained at in vivo conditions. Nowadays, the available collections are limited either in the number of tissues or the measured frequencies, and hence researchers have to make use of more complete databases but that were performed ex vivo. The drawback of using these collections is that results can be compromised by factors such as lack of blood perfusion and tissue dehydration. Developing this new database can facilitate the design of applications that needs of a careful knowledge of these properties. / Fornés Leal, A. (2019). Dielectric Characterization of Biological Tissues for Medical Applications [Tesis doctoral]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/132188

Web-based learning should move away from static transmission of instruction to dynamic pages for effective interactive learning. Furthermore, automated assessment of learning should move beyond rigid quizzes or multiple-choice questions. This study describes the design, development, implementation, testing and evaluation of two prototypes of an electronic assessment tool to enhance the effectiveness of automated assessment. The tool was developed in the context of a distance-learning organisation and was built according to a development research model entailing a cyclic design-intervention-outcomes process. The first variant, E-Grader, was developed to test an algorithm for assigning marks to open-ended textual responses. The second variant, Web-Grader, was an interactive web-based extension of E-Grader. It provided immediate interactive support to students as they responded textually to content-based questions. This multi-disciplinary study incorporates principles and techniques from software engineering, formal computer science, database development and instructional design in the quest towards electronic assessment of web-based textual inputs. / Computing / M.Sc. (Information Systems)

Includes bibliographical references / Pages not numbered / Music has formed a part of human life as far back as demonstrable. Music existed long before musical instruments made their appearance. The examination of textual evidence read in conjunction with the available archaeologic evidence from the time and area clearly demonstrates which musical instruments were available and the instances they were used at. It clearly points to the lyre as the primary proponent of the musical culture of the time with regards to melodic music. This is confirmed from what we learn from the ancient tuning tablets. There thus is a direct demonstrable connection between the instrument and the theory of the time. Work done on the musical elements of the cantillation marks of the Hebrew Bible comfortably fits into this framework and appears to be a direct influence on the manner in which the Psalms were sung and composed. A combination of literary, archaeological and musical sources can thus be used within a literary and historical approach to demonstrate the availability of musical instruments in AIP, the manner in which tonality was recorded and its influence on the development of the Psalms. / Old Testament and Ancient Near Eastern Studies / M.A. (Biblical Archaeology)

Despite widespread recognition by science educators, researchers and K-12 frameworks that scientific inquiry should be an essential part of science education, typical classrooms and assessments still emphasize rote vocabulary, facts, and formulas. One of several reasons for this is that the rigorous assessment of complex inquiry skills is still in its infancy. Though progress has been made, there are still many challenges that hinder inquiry from being assessed in a meaningful, scalable, reliable and timely manner. To address some of these challenges and to realize the possibility of formative assessment of inquiry, we describe a novel approach for evaluating, tracking, and scaffolding inquiry process skills. These skills are demonstrated as students experiment with computer-based simulations. In this work, we focus on two skills related to data collection, designing controlled experiments and testing stated hypotheses. Central to this approach is the use and extension of techniques developed in the Intelligent Tutoring Systems and Educational Data Mining communities to handle the variety of ways in which students can demonstrate skills. To evaluate students' skills, we iteratively developed data-mined models (detectors) that can discern when students test their articulated hypotheses and design controlled experiments. To aggregate and track students' developing latent skill across activities, we use and extend the Bayesian Knowledge-Tracing framework (Corbett & Anderson, 1995). As part of this work, we directly address the scalability and reliability of these models' predictions because we tested how well they predict for student data not used to build them. When doing so, we found that these models demonstrate the potential to scale because they can correctly evaluate and track students' inquiry skills. The ability to evaluate students' inquiry also enables the system to provide automated, individualized feedback to students as they experiment. As part of this work, we also describe an approach to provide such scaffolding to students. We also tested the efficacy of these scaffolds by conducting a study to determine how scaffolding impacts acquisition and transfer of skill across science topics. When doing so, we found that students who received scaffolding versus students who did not were better able to acquire skills in the topic in which they practiced, and also transfer skills to a second topic when was scaffolding removed. Our overall findings suggest that computer-based simulations augmented with real-time feedback can be used to reliably measure the inquiry skills of interest and can help students learn how to demonstrate these skills. As such, our assessment approach and system as a whole shows promise as a way to formatively assess students' inquiry.

Despite widespread recognition by science educators, researchers and K-12 frameworks that scientific inquiry should be an essential part of science education, typical classrooms and assessments still emphasize rote vocabulary, facts, and formulas. One of several reasons for this is that the rigorous assessment of complex inquiry skills is still in its infancy. Though progress has been made, there are still many challenges that hinder inquiry from being assessed in a meaningful, scalable, reliable and timely manner. To address some of these challenges and to realize the possibility of formative assessment of inquiry, we describe a novel approach for evaluating, tracking, and scaffolding inquiry process skills. These skills are demonstrated as students experiment with computer-based simulations. In this work, we focus on two skills related to data collection, designing controlled experiments and testing stated hypotheses. Central to this approach is the use and extension of techniques developed in the Intelligent Tutoring Systems and Educational Data Mining communities to handle the variety of ways in which students can demonstrate skills. To evaluate students' skills, we iteratively developed data-mined models (detectors) that can discern when students test their articulated hypotheses and design controlled experiments. To aggregate and track students' developing latent skill across activities, we use and extend the Bayesian Knowledge-Tracing framework (Corbett & Anderson, 1995). As part of this work, we directly address the scalability and reliability of these models' predictions because we tested how well they predict for student data not used to build them. When doing so, we found that these models demonstrate the potential to scale because they can correctly evaluate and track students' inquiry skills. The ability to evaluate students' inquiry also enables the system to provide automated, individualized feedback to students as they experiment. As part of this work, we also describe an approach to provide such scaffolding to students. We also tested the efficacy of these scaffolds by conducting a study to determine how scaffolding impacts acquisition and transfer of skill across science topics. When doing so, we found that students who received scaffolding versus students who did not were better able to acquire skills in the topic in which they practiced, and also transfer skills to a second topic when was scaffolding removed. Our overall findings suggest that computer-based simulations augmented with real-time feedback can be used to reliably measure the inquiry skills of interest and can help students learn how to demonstrate these skills. As such, our assessment approach and system as a whole shows promise as a way to formatively assess students' inquiry.

L'acquisition autonome de representations et de fonctionnalites en robotique pose de nombreux problemes theoriques. Aujourd'hui, les systemes robotiques autonomes sont concus autour d'un ensemble de fonctionnalites. Leurs representations du monde sont issues de l'analyse d'un probleme et d'une modelisation prealablement donnees par les concepteurs. Cette approche limite les capacites d'apprentissage. Nous proposons dans cette these un systeme ouvert de representations et de fonctionnalites. Ce systeme apprend en experimentant son environnement et est guide par l'augmentation d'une fonction de valeur. L'objectif du systeme consiste a agir sur son environnement pour reactiver les representations dont il avait appris une connotation positive. Une analyse de la capacite a generaliser la production d'actions appropriees pour ces reactivations conduit a definir un ensemble de proprietes necessaires pour un tel systeme. Le systeme de representation est constitue d'un reseau d'unites de traitement semblables et utilise un codage par position. Le sens de l'etat d'une unite depend de sa position dans le reseau. Ce systeme de representation possede des similitudes avec le principe de numeration par position. Une representation correspond a l'activation d'un ensemble d'unites. Ce systeme a ete implemente dans une suite logicielle appelee NeuSter qui permet de simuler des reseaux de plusieurs millions d'unites et milliard de connexions sur des grappes heterogenes de machines POSIX. Les premiers resultats permettent de valider les contraintes deduites de l'analyse. Un tel systeme permet d'apprendre dans un meme reseau, de facon hierarchique et non supervisee, des detecteurs de bords et de traits, de coins, de terminaisons de traits, de visages, de directions de mouvement, de rotations, d'expansions, et de phonemes. NeuSter apprend en ligne en utilisant uniquement les donnees de ses capteurs. Il a ete teste sur des robots mobiles pour l'apprentissage et le suivi d'objets.

Web-based learning should move away from static transmission of instruction to dynamic pages for effective interactive learning. Furthermore, automated assessment of learning should move beyond rigid quizzes or multiple-choice questions. This study describes the design, development, implementation, testing and evaluation of two prototypes of an electronic assessment tool to enhance the effectiveness of automated assessment. The tool was developed in the context of a distance-learning organisation and was built according to a development research model entailing a cyclic design-intervention-outcomes process. The first variant, E-Grader, was developed to test an algorithm for assigning marks to open-ended textual responses. The second variant, Web-Grader, was an interactive web-based extension of E-Grader. It provided immediate interactive support to students as they responded textually to content-based questions. This multi-disciplinary study incorporates principles and techniques from software engineering, formal computer science, database development and instructional design in the quest towards electronic assessment of web-based textual inputs. / Computing / M.Sc. (Information Systems)

Investment Company with Variable Capital (SICAV) The thesis elaborates on the Czech regulation of the investment company with variable capital ("SICAV"). It is divided into six chapters. In chapter one, the theory of collective investments and its practice in the Czech Republic is described, along with data of the use of SICAVs. Next, the legislation concerning SICAVs, and reasons for its introduction, are summarised. Chapter three includes the definition of Czech SICAV and its features as an investment fund and join-stock company. In chapter four, the variability of its capital is discussed in broader context of the Czech law system, which is based on a different conceptual approach, and also the capital requirements of SICAVs are mentioned. Chapter five concerns with the obligatory division of assets of Czech SICAVs, leading to the last chapter describing the founders' and investment shares, and rights of shareholders tied to them. The primary aim of the thesis, in context of an absence of any thorough publications on Czech SICAVs, is to provide a comprehensive description of the distinctive character of Czech SICAVs, and on this basis to point out the parts of legislation that are not set appropriately. In these cases, a specific interpretation of problematic parts of regulation is suggested, and in case...

Communication seems to play a pivotal role in any high school classroom. But it was found those classes or certain individual students shy away from engaging in effective communication during natural science lessons in Swaziland. One of the directives in the Swaziland National Education Policy states that syllabuses for studies in Form 4 and 5 should enable learners to develop essential skills which include communication and language skills. This study then, on realising that there was a gap between what was stated in the Education Policy and what was actually the case in the natural science classrooms, sought for a solution that would encourage effective communication in natural sciences. Therefore, the main purpose of the study was to encourage active participation of high school students in natural science lessons. The main research question posed for this purpose was: Can student motivation enhance classroom discourse for the negotiation of science understanding? Five sub-questions emanated from the main research question: (a) How does classroom discourse relate to natural science understanding? (b) What effect does external motivation have on discourse during natural science lessons? (c) What is the effect of feedback during natural science learning? (d) How can feedback be enhanced in the natural science class? (e) Which teaching strategies improve interactions during natural science learning? The study is organised into five chapters. The first chapter summarises the whole study by giving the problem statement, research aim and objectives, definition of terms, as well as chapter divisions. Chapter two provides the background to the study through the discussion of education theories based on classroom discourse and motivation. The third chapter presents detailed information about the research design, methods of data collection and analysis, as well as a proposed method for motivating students. The fourth chapter presents the research results, analysis and discussion. The fifth and the final chapter presents research findings, concluding remarks drawn from the research findings, as well as recommendations for similar future research. The case study style uses a qualitative, descriptive and exploratory approach. The study concentrated on theories explaining learning and motivation. The sample comprised six purposefully selected students and their two physical science teachers. Data were collected using the standardised open-ended interview and non-participant lesson observation methods, and from documents. The data were collected in two phases, the pre-motivation phase and the motivation phase. The collected data was further categorised into two segments, with each segment being a unit of analysis. One of the segments was composed of oral interchanges, while the other was composed of students’ written work. The data was then transcribed, coded, analysed and discussed using the thematic discourse analysis approach. The principles of triangulation, reliability and validity ensured the credibility of the study remained intact. Research ethics were also observed by the researcher and there was trust, respect and autonomy during data collection. The ethics observed included informed consent, confidentiality, beneficence, anonymity and non-malificence. Permission to collect data was sought and obtained from all concerned. The motivation method helped the physics group improve more (55%) than the chemistry group (7%) in tests. In the overall performance the two groups improved more or less the same: the chemistry group improved by 4% while the physics group improved by 5%. There were three main findings for the study and they revolved around the purpose and the research question. The first major finding was that the motivation method used with the students instilled self-discipline in the students, resulting in self-regulated behaviour and better understanding of science concepts. The finding suggested that motivated students are self-disciplined and take ownership of their learning. The second major finding was that during the motivation phase of data collection interactions improved between the students and their science teachers. These interactions were in the form of classroom talk, submission of school work and feedback. It was inferred that motivated students communicate more effectively and with better understanding of the concepts taught. The third major revelation was that the students were motivated by learner-centred teaching strategies and the use of teaching aids in a science laboratory. A main finding for the first sub-question was that the more students interacted with each other, with their natural science teachers, and with their books the more they appreciated and understood science concepts. For the second sub-question the main finding was, the motivation method used with the students improved discourse during natural science lessons. The marks the students were awarded gave them the energy to engage more in science activities and to behave well. The main finding for the third sub-question was that prompt feedback and positive comments motivated students to engage more in science discourse and to understand science concepts better. An important finding from the fourth sub-question was that prompt and positive feedback enhanced feedback, as well as giving students tasks that were not too far above their abilities, enhanced feedback in the natural science class. For the fifth sub-question it was found that student-centred teaching methods as well as teaching aids and learning in science laboratories improved interactions during natural science learning. / Curriculum and Instructional Studies / D. Ed. (Curriculum Studies)

The facilitator model for dual credit offers a way for student to earn directly transcripted credit to colleges and universities, overcoming many barriers faced by other dual credit models. Successful implementation of this model requires high degree of involvement from the cooperating institution. This IRB approved qualitative case study explored the needs of five teacher facilitators in both summer professional development and on-going support throughout the school year when implementing a facilitator model for dual credit with open-ended design coursework. Code-recode and axial coding techniques were applied to over 90 hours of transcribed data, artifacts, and observations from a seven month period to find emerging themes and offer recommendations for implementation.<p></p>