Neste estudo foi realizada a tradução e adaptação transcultural para o português no contexto da cultura brasileira e validada a versão do Questionário de Incapacidade decorrente de Dor Orofacial de Manchester. As diretrizes seguidas para a tradução e adaptação transcultural foram propostas por Beaton et al. (2000) e Wild et al. (2005). A versão final instituída (Brasil - MOPDS) foi aplicada em 50 pacientes com Dor Orofacial da clínica ambulatorial de ATM e Oclusão do Departamento de Prótese Dentária da Faculdade de Odontologia da Universidade de São Paulo. A Brasil MOPDS foi administrada duas vezes por um entrevistador (intervalo de 15-20 dias) e uma vez por um entrevistador independente. A versão brasileira do questionário OHIP-14 e a Escala Visual Analógica (EVA) foram realizadas em uma das entrevistas. Para análise da consistência interna foi utilizado Alpha de Cronbach e o Coeficiente de Correlação de Spearman. O Coeficiente de Correlação Intraclasse (ICC) e o Coeficiente de Correlação de Bland-Altmann (CCBA) foram computados para avaliar a validade e a confiabilidade externa e interna. A consistência interna encontrada foi alta ( = 0,9175) e as correlações interobservador (ICC = 0,924) e intraobservador (ICC = 0,982) foram excelentes. As validades comparadas ao OHIP- 14 (r = 0,857) e a EVA (r = 0,758) foram altas. A Brasil MOPDS foi validada e adaptada com sucesso para aplicação em pacientes brasileiros, com validade e confiabilidade interna e externa satisfatória. / In this study was done the translation and cross cultural adaptation of the Manchester Orofacial Pain Disability for the Portuguese language. The guidelines followed for this process was suggested by Beaton et al. (2000) and Wild et al. (2005). Therefore, the final version (Brazil - MOPDS) was established and applied in 50 patients with Orofacial Pain selected in TMJ and Occlusion clinic ambulatory of University of São Paulo University Dentistry School. The Brazil MOPDS was administered twice by one interviewer (15-20 days interval) and once by an independent interviewer. The Brazilian OHIP short version (OHIP-14) and the Visual Analogical Scale (VAS) were applied on the same day. For internal consistency analysis, the Cronbach´s Alpha test, Spearmans Correlation Coefficient, intra-class Correlation Coefficient (ICC) and Bland-Altmans Correlation Coefficient were used to evaluate the validation and internal and external reliability. Results: The internal consistency found was high (=0, 9175). Inter-observer correlations (ICC = 0.924) and intra-observer (ICC= 0.982) were excellent. Validity compared with OHIP-14 (r= 0.857) and VAS (r= 0.758) were high. Brazil MOPDS was successfully translated and adapted to be applied to Brazilian patients, with satisfactory internal and external reliability.

Orientador: Roger William Fernandes Moreira / Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba / Made available in DSpace on 2018-08-24T16:06:55Z (GMT). No. of bitstreams: 1 Marchiori_EricaCristina_D.pdf: 484604 bytes, checksum: 57495eb26b1ce8df8060445371d9671a (MD5) Previous issue date: 2014 / Resumo: Objetivos: Avaliar a prevalência, fatores de risco e curso clínico da dor neuropática (DN) após osteotomia sagital dos ramos mandibulares (OSRM) em uma grande amostra de pacientes. Materiais e Métodos: Estudo retrospectivo realizado em dois centros médicos do Hospital Kaiser Permanente da Norte da Califórnia, no período de janeiro de 2007 até setembro de 2012, nos pacientes submetidos à OSRM. Fatores demográficos, clínicos e cirúrgicos foram identificados nos prontuários dos pacientes, bem como comorbidades associadas. A prevalência, sinais e sintomas, características da dor e a resposta ao tratamento nos pacientes afetados foram analisados. Resultados: Os autores identificaram 1.778 pacientes que foram submetidos à OSRM e, destes, 107 foram excluídos de acordo com critérios pré-definidos. A média de idade dos pacientes (1.671) foi de 24 anos (intervalo interquartil de 19 a 35 anos) e 62,4% eram do gênero feminino. Sete pacientes desenvolveram DN após OSRM, cuja prevalência foi de 0,42%. Todos eles eram mulheres, cuja média de idade foi de 48 anos. Os fatores de risco para o desenvolvimento de DN após OSRM incluíram: idade superior a 40 anos (p = 0.0098), depressão (p = 0.0100), e gênero feminino (p = 0.0497). O inicio da DN ocorreu em uma média de 30 dias de pós-operatório (18 a 56 dias), com média de duração de 52 dias (30 a 69,5 dias). Todos os pacientes responderam favoravelmente à medicações anticonvulsivantes (n = 6) ou antidepressivas tricíclicas (n = 1), além de nenhum dos pacientes ter desenvolvido dor crônica pós-cirúrgica. Conclusões: A dor de origem neuropática é uma complicação infrequente após OSRM, acometendo 1 a cada 238 pacientes nesta amostra. A curta duração e a reposta favorável às medicações empregadas reforça esse achado. Os resultados dessa investigação chamam a atenção para a necessidade de futuros estudos prospectivos para melhor compreensão da DN pós-operatória / Abstract: Purpose: To estimate the prevalence of, risk factors for, and clinical course of neuropathic pain (NPP) after sagittal split ramus osteotomy (SSRO) of the mandible in a large cohort of patients. Materials and Methods: A retrospective cohort of all patients who underwent SSRO at 2 medical centers within Kaiser Permanente Northern California from January 2007 through September 2012 was assembled. Demographic, clinical, and surgical factors were collected from medical records and relevant comorbidities were identified. The prevalence of NPP in the cohort was calculated and the clinical signs, symptoms, temporal characteristics and treatment response in affected patients were noted. Results: The authors identified 1.778 patients who underwent SSRO and excluded 107 patients according to predefined criteria. The remaining 1.671 patients had a median age of 24 years (interquartile range from19 to 35 years) and 62.4% were women. Seven patients developed NPP after SSRO, which was an overall prevalence of 0.42%. All patients with NPP in this cohort were women and had a median age of 48 years. The risk factors for developing NPP after this surgery were age over 40 years (p = 0.0098), depression (p = 0.0100), and female gender (p = 0.0497). NPP developed an average of 30 days postoperatively (range, 18 to 56 days) and persisted for a median duration of 52 days (range, 30 to 69.5 days). All patients responded favorably to anticonvulsant (n = 6) or tricyclic (n = 1) medications, and no patients developed chronic postsurgical pain. Conclusions: NPP was an infrequent complication after SSRO, occurring in 1 of 238 patients in this cohort. The short duration and positive response to medication are reassuring findings. The results of this investigation highlight the need for prospective studies to further understand the spectrum of postoperative NPP / Doutorado / Cirurgia e Traumatologia Buco-Maxilo-Faciais / Doutora em Clínica Odontológica

Orientador: Fausto Bérzin / Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba / Made available in DSpace on 2018-08-24T18:09:55Z (GMT). No. of bitstreams: 1 Ruivo_MariliaAraujo_M.pdf: 2483740 bytes, checksum: afe6aba8e65a3b5d2c6df405a94c6217 (MD5) Previous issue date: 2014 / Resumo: O estudo investigou a prevalência da dor orofacial e sua associação com a auto-percepção da qualidade de vida em adultos brasileiros, residentes do município de Piracicaba, São Paulo. A amostra randomizada foi composta por 400 voluntários residentes no município de Piracicaba-SP, com faixa etária entre 20 a 50 anos de idade, sem restrição de gênero e nível econômico. Os voluntários foram avaliados em relação às características sócio-demográficas, prevalência, localização, frequência, duração e severidade da dor, e também em relação à sua auto-percepção do nível de qualidade de vida. As pessoas que compuseram a amostra foram aleatoriamente abordadas em seis diferentes pontos de passagem do município, estrategicamente selecionados como pontos de grande movimento populacional, e os dados foram obtidos por meio da aplicação de dois questionários: 1) Questionário de Dor Orofacial, que investigou a prevalência e as características da dor; 2) WHOQOL-BREF, para avaliação da qualidade de vida relativa à percepção dos domínios físico, psicológico, relações sociais e meio ambiente do indivíduo. Os dados foram analisados estatisticamente através do sistema SAS que calculou os testes qui-quadrado; Cocrham, Mantel e Haenszel; qui-quadrado de Wald; qui-quadrado de Mantel e Haenszel e Odds ratio, com nível de significância de 5%. A prevalência de dor orofacial verificada na população foi de 54,75%, com intensidade predominantemente forte (21,30%), de recorrência diária (41,10%) e presente há mais de seis meses (91,32%). As regiões mais acometidas foram a cabeça (36%), seguida dos ombros (22,25%), e a região intra-oral foi o local menos frequentemente apontado pelos voluntários (6%). Não se observou associação significativa entre a presença de dor orofacial e os fatores idade, nível econômico e escolaridade (p>0,05); no entanto, o estudo verificou significativa prevalência de dor entre as mulheres. Os resultados também permitem verificar que enquanto quase metade dos voluntários que não relataram dor consideram ter boa qualidade de vida (43,09%), apenas 21,92% das pessoas que referiram dor orofacial, consideram a qualidade de vida como boa (p<0,05); o estudo também apontou maior frequência de insatisfação com a qualidade do sono em pacientes que relataram dor (p<0,05). Entretanto, não foi observada associação significativa entre a frequência de sentimentos negativos, como depressão, ansiedade, mau humor e desespero, e a presença de dor orofacial. O estudo ressalta alta prevalência de dor orofacial com significante morbidade da população acometida por esta condição, e seu impacto sobre a auto-percepção da qualidade de vida / Abstract: The study assessed the prevalence of orofacial pain and its association with self-perceived quality of life in Brazilian adults, residents of Piracicaba-SP, São Paulo. A random sample of 400 volunteers living in Piracicaba, aged between 20-50 years of age, without restriction of gender and socioeconomic status, were evaluated in relation to socio-demographic characteristics, prevalence, location, frequency, duration and severity of pain, and also in relation to their self-perceived level of quality of life. People in the sample were randomly assessed in six different crossing points of the city, strategically selected as points of great population movement, and the data were obtained through the application of two questionnaires: 1) Orofacial Pain Questionnaire, which investigated the prevalence and characteristics of pain; 2) WHOQOL-BREF to evaluate quality of life on individual perception of physical, psychological, social relationships and personal environment aspects. Data were statistically analyzed using the SAS system that calculated the chi-square tests ; Cocrham , Mantel and Haenszel , Wald chi-square , chi -square and Mantel -Haenszel odds ratio and, with a significance level of 5 % . The prevalence of orofacial pain observed was 54.75 %, with predominantly intense pain (21.30%), daily recurrence (41.10%) and present for more than six months (91.32%). The most affected regions were the head (36%), followed by the shoulder (22.25%), and intra-oral region was the site less often pointed out by volunteers (6%). No significant association was observed between the presence of orofacial pain and age, economic status and educational level (p>0.05), however, the study found a significant prevalence of pain among women. Data also found that while nearly half of the volunteers reported no pain considered to have good quality of life (43.09%), only 21.92 % of people who reported orofacial pain, consider the quality of life as good (p<0.05). According to the study, also a higher frequency of patients who reported pain related sleep disturbance (p<0.05). However, no significant association was observed between the the presence of orofacial pain and frequency of negative psychological disability such as depression, anxiety, moodiness and despair. The study highlights the high prevalence of orofacial pain with significant morbidity of the population affected by this condition, and its impact on self-perception of quality of life / Mestrado / Anatomia / Mestra em Biologia Buco-Dental

The present study explored the antinociceptive effects of H3 (R-alpha-methylhistamine) and GABAB (baclofen) receptor ligands in an orofacial model of pain in rats. Orofacial pain was induced by subcutaneous injection of formalin (50 μl, 5 %) in the upper lip region, and the number of jumps and time spent face rubbing was recorded for 40 min. Formalin produced a marked biphasic pain response; first phase, 0-10 min (jumps), and second phase, 15-40 min, (rubbing). Baclofen (50 μg) injected into the rat wiskerpad 5 min before formalin administration suppressed both phases of pain whereas R-alpha-methylhistamine (12.5 μg) abolished the first phase only. Brains were taken immediately after behavioral testing was completed. HPLC/ED analysis showed that 5-hydroxytryptamine (5-HT) turnover was increased in hippocampus, thalamus, and brain stem of all formalin groups, excepting the baclofen group in which the balance of 5-HT metabolism was restored to control values. These findings demonstrate that GABAB receptors represent peripheral targets for analgesia. Consequently, locally administered baclofen may be a useful approach in treating inflammatory trigeminal pain.

The present study explored the antinociceptive effects of H3 (R-alpha-methylhistamine) and GABAB (baclofen) receptor ligands in an orofacial model of pain in rats. Orofacial pain was induced by subcutaneous injection of formalin (50 μl, 5 %) in the upper lip region, and the number of jumps and time spent face rubbing was recorded for 40 min. Formalin produced a marked biphasic pain response; first phase, 0-10 min (jumps), and second phase, 15-40 min, (rubbing). Baclofen (50 μg) injected into the rat wiskerpad 5 min before formalin administration suppressed both phases of pain whereas R-alpha-methylhistamine (12.5 μg) abolished the first phase only. Brains were taken immediately after behavioral testing was completed. HPLC/ED analysis showed that 5-hydroxytryptamine (5-HT) turnover was increased in hippocampus, thalamus, and brain stem of all formalin groups, excepting the baclofen group in which the balance of 5-HT metabolism was restored to control values. These findings demonstrate that GABAB receptors represent peripheral targets for analgesia. Consequently, locally administered baclofen may be a useful approach in treating inflammatory trigeminal pain.

Abstract  Aim: The aim of this study was to evaluate the effects of the structured implementation of screening and diagnostics of orofacial pain and jaw function in the affiliated general dentistry clinics of FTV VGR. Furthermore, evaluate differences in treatment between patients with and without a dental care subscription.   Material and method: Data regarding TMD treatments (600-series treatments) performed every month were gathered from the affiliated clinics over a 24-month timespan stretching between 2019-2021. Each treatment code was divided into three categories, all patients, patients with dental care subscription and patients without a dental care subscription. Parametrical statistics were used to assess the change of each treatment code performed before compared to after the implementation of Brief DC/TMD. The student's paired t-test was used and a probability level of P&lt;0.05 was considered significant.    Results: The proportion of patients that received treatments and number of treatments performed saw a significant increase after the implementation project. Each specific treatment within the 600-series increased except for 604 (soft occlusalt splint) and 607 (occlusal adjustment) which decreased. Among the three treatments that increased, two were significant: 601, hard acrylic maxillary occlusal splint and 606, jaw exercises. Patients with a dental care subscription received TMD-treatment in a significantly higher degree.    Conclusion: The present study indicates that the implementation of Brief DC/TMD increased diagnostics and treatment of TMD within the general dentistry practice of Folktandvården Västra Götaland during the analysed time periods. Further research is needed to determine the cause behind the performance disparities among the individual clinics. / Sammanfattning Syfte: Att utvärdera effekten av en strukturerad implementation av screening och diagnostik av orofacial smärta och käkfunktion inom Folktandvården Västra Götalands tandvårdskliniker. Samt jämföra patienter med och utan Frisktandvård. Material och metod: Data gällande behandling av bettfysiologiska besvär (600-serie åtgärdskoder) samt undersökningar utförda varje månad var samlade från de 118 anslutna klinikerna under en 24-månadersperiod som varade mellan 2019–2021. Varje parameter delades upp i tre kategorier, alla patienter, patienter med Frisktandvård och patienter utan Frisktandvård. Parametrisk statistik användes för att bedöma förändringarna som utfördes före jämfört med efter implementationen av kort DC/TMD. Students parade t-test användes för att beräkna signifikansen av de observerade förändringarna där ett P-värde &lt;0,05 ansågs signifikant. Resultat: Andelen patienter som fick behandling och antalet utförda behandlingar som en helhet såg en signifikant ökning efter implementationsprojektet i jämförelse med före (procentuell skillnad på 46,8% respektive, 56,5%). Varje enskild behandling inom 600-serien såg en ökning, förutom kod 604 (mjukplastskena) och 607 (bettslipning för ocklusal stabilisering) vilket minskade. Bland de tre behandlingarna som såg en ökning, var två signifikanta: 601 (Bettskena i hård akrylat i överkäken, utförd på bettfysiologisk indikation) samt 606, (motorisk aktivering). Patienter med Frisktandvård fick behandling mot sina bettfysiologiska besvär i en signifikant högre grad. Slutsats: Denna studie indikerar att implementation av kort DC/TMD ökade diagnostik och behandling av TMD inom Folktandvården Västra Götaland under de analyserade tidsperioderna. Vidare forskning behövs för att utvärdera orsaken bakom prestationsskillnaderna mellan de individuella klinikerna.

Syfte. Studiens syfte var att retrospektivt undersöka vilka kliniska variabler, bedömda under specialistundersökning av orofacial smärta, som kan förutsäga närvaro av en störd central smärtmodulering (DCPM). Material och metod. DC/TMD-data hämtades ur patientjournaler från 86 patienter som undersökts på Orofaciala smärtenheten på Malmö Universitet under perioden september 2012 till och med december 2013. Undersökta variabler omfattade smärtintensitet, smärtutbredning, smärtrelaterad nedsatthet, psykosociala variabler, refererad smärta samt kliniska fynd under somatosensoriska undersökningar. Baserat på denna data delades patienterna upp i en DCPM-grupp och en grupp utan DCPM. Allodyni, hyperalgesi, dysestesi, wind-up, regional/generell smärtutbredning samt eftersensation ansågs vara markörer för DCPM. Icke-parametriska statistiska analyser användes och en sannolikhetsnivå på P<0,05 ansågs vara signifikant. Resultat. Graden av ospecifika fysiska symptom och antalet refererande smärtor var signifikant högre i DCPM-gruppen. Den multivariata logistiska regressionen visade att ospecifika fysiska symptom, stress, smärtduration, smärtintensitet, smärtrelaterad nedsatthet, antalet refererande smärtpunkter, maximal gapning med och utan smärta, ångest samt antalet smärtinducerande käkrörelser var signifikanta marörer för DCPM (LR Chi2 = 26.89, p = 0.003, Pseudo R2 = 0.29). Slutsats. Denna studie indikerar att stress, ångest, smärtduration, smärtintensitet, smärtrelaterad nedsatthet, antalet refererande smärtpunkter, maximal gapning med och utan smärta samt antalet smärtinducerande käkrörelser är associerat med DCPM hos patienter med orofacial smärta. / Objective. To retrospectively investigate clinical variables that can predict the presence of disturbed central pain modulation (DCPM). Material and methods Medical records of 86 patients examined at the Orofacial Pain Unit at Malmö University from September 2012 to December 2013 were examined regarding pain intensity, pain distribution, pain-related disability, psychosocial variables, referred pain as well as somatosensory changes. Based on these variables, the patients were divided into a disturbed central pain modulation (DCPM) group and a non-DCPM group. Allodynia, hyperalgesia, dysesthesia, increased wind-up, regional/general pain distribution and aftersensation were considered as markers for DCPM. Non-parametric statistics were used and a probability level of P<0.05 was considered as significant. Results. The degree of unspecific physical symptoms and the number of sites eliciting pain referral were significantly higher in the DCPM group. In the multivariate regression model, the independent variables physical symptoms, stress, pain duration, characteristic pain intensity, pain-related disability, number of sites with referred pain, maximum mouth opening with and without pain, anxiety, and number of pain eliciting jaw movements significantly predicted DCPM (LR Chi2 = 26.89, p = 0.003, Pseudo R2 = 0.29). Conclusion. This study indicates that stress, anxiety, orofacial pain and its consequences, unspecific physical symptoms and jaw dysfunction are clinical signs of DCPM in patients with orofacial pain. Also, high number of palpations sites with referred pain over the masseter and temporal muscles and the TMJ indicate presence of DCPM.

SyfteUndersöka påverkan av kronisk orofacial smärta och psykologiska faktorer på sömnkvalitet vid käkmuskelmyalgi.Material och metoderDenna retrospektiva studie omfattade 37 patienter (6 män, 31 kvinnor, medelålder: 49 år) med käkmuskelmyalgi. Sömnkvalitet (Pittsburgh Sleep Quality Index), smärtintensitet och smärtrelaterad funktionsnedsättning (Graded Chronic Pain Scale), depression (Patient Health Questionnaire-9), ångest (General Anxiety Disorder-7), stress (Perceived Stress Scale-10) och katastrofiering (Patient Catastrophizing Scale) undersöktes med varierade formulär. Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) användes för att identifiera patienter med myalgi i käkmuskulatur.Resultat75% av patienterna rapporterade dålig sömnkvalitet, 73% rapporterade minst mild depressionsgrad, 54% rapporterade minst mild ångest, 59% rapporterade måttlig stressnivå och 38% rapporterade kliniskt relevant katastrofiering. Försämrad sömnkvalitet var relaterad till depression (rs = 0.45, n = 37, p = 0.008) ångest (rs = 0.46, n = 37, p = 0.007), stress (rs = 0.43, n = 37, p = 0.014) och katastrofiering (rs = 0.37, n = 37, p = 0.034). Multivariat logistisk regression visade att smärtintensitet, smartrelaterad funktionsnedsättning, depression, ångest, stress, katastrofiering och antal käkmuskler med refererad palpationssmärta förklarade dålig sömnkvalitet signifikant (p = 0.031).KonklusionSömnkvaliteten hos patienter med käkmuskelmyalgi påverkas i hög grad av kronisk smärtintensitet, smärtrelaterad funktionsnedsättning, antal käkmuskler med refererad palpationssmärta och depression samt ångest, stress och katastrofiering. / AimInvestigate the influence of chronic orofacial pain and psychological factors on sleep quality in patients with myalgia of the masticatory muscles.Material and methodsThis retrospective study included 37 patients (6 men, 31 women, mean age: 49 years) with masticatory muscle myalgia. Sleep quality (Pittsburgh Sleep Quality Index), pain intensity and pain-related disability (Graded Chronic Pain Scale), depression (Patient Health Questionnaire-9), anxiety (General Anxiety Disorder-7), stress (Perceived Stress Scale-10) and catastrophizing (Patient Catastrophizing Scale) were assessed by questionnaires. The Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) were used to identify patients with myalgia.Results75% of the patients reported poor sleep quality, 73% reported at least mild depression degree, 54% reported at least mild degree of anxiety, 59% reported at least a moderate stress level and 38% reported a clinically relevant degree of catastrophizing. Impaired sleep quality was related to degree of depression (rs = 0.45, n = 37, p = 0.008), anxiety (rs = 0.46, n = 37, p = 0.007), stress (rs = 0.43, n = 37, p = 0.014) and catastrophizing (rs = 0.37, n = 37, p = 0.034). Multivariate logistic regression showed that characteristic pain intensity, degree of pain-related disability, depression, anxiety, stress, catastrophizing and number of masticatory muscle sites with referred pain significantly explained poor sleep quality (p = 0.031).ConclusionSleep quality in patients with masticatory myalgia is influenced by chronic pain intensity and related disability, number of masticatory muscle sites with referred pain as well as depression, anxiety, stress and catastrophizing.

A dor orofacial compreende todas as dores que envolvem os tecidos moles e mineralizados da cavidade oral e da face, pode ser referida na região da cabeça e/ou pescoço. A etiologia da disfunção temporomandibular (DTM) é multifatorial, são distúrbios musculoesqueléticos que afetam o sistema estomatognático, os músculos mastigatórios e/ou estruturas associadas. Uma disfunção muito prevalente é a dor miofascial. O front-plateau é um dispositivo de resina acrílica instalado nos dentes superiores anteriores, que desoclui os dentes posteriores, proporcionando desprogramação neuromuscular. O objetivo deste estudo foi avaliar a atividade eletromiográfica, o limiar de dor à pressão (LDP) dos músculos temporal e masseter, e a força de mordida molar máxima de participantes com dor miofascial, antes e após a instalação da placa anterior \"front-plateau\". As participantes foram recrutadas e atendidas na Clínica de Dor Orofacial do DAPE da FORP-USP. Para tanto, foram avaliadas 22 mulheres entre 20 e 60 anos. As participantes foram submetidas inicialmente aos exames de eletromiografia (EMG), eletromiógrafo MyoSystem-Br1, limiar de dor a pressão (LDP) algômetro Kratos® e foi aferida força de mordida molar máxima (FMM) por meio do dinamômetro Kratos® IDDK. Foram formados dois grupos, no grupo 1 (G1) 11 participantes usaram o front-plateau por sete dias, 16 horas nos três primeiros dias e por oito horas nos próximos quatro dias, sendo que o tratamento foi interrompido após este período. O grupo 2 (G2), com 11 participantes, iniciou o tratamento idem ao G1 e após sete dias continuaram usando o front-plateau por oito horas diárias por mais três semanas, totalizando 1 mês de uso. Após o tratamento, as participantes dos dois grupos foram novamente avaliadas quatro semanas após a primeira avaliação. Os dados foram analisados com auxílio do software R (R® Foundation for Statistical Computing, Áustria). Os valores reais ou transformados das variáveis foram comparados entre os tratamentos, dias de avaliação e sua interação pela Analise de Variância (ANOVA) em um delineamento interamente casualizado com medidas repetidas no tempo. Para as variáveis que apresentaram diferença estatística, as médias foram comparadas pelo pós-teste de Tukey (p<0,05) e os dados apresentados como a média ± o erro padrão (EP). Foi encontrado relevância estatística em todas as variáveis das análises feitas pelo algômetro durante a utilização do front-plateau, havendo diminuição da sensibilidade dolorosa e aumento do LDP em todos os músculos analisados. Não houve qualquer alteração estatisticamente significativa na FMM no período de utilização do front plateau. Na eletromiografia foi encontrados valores significativos nos padrões posturais de lateralidade direita (LD) e lateralidade esquerda (LE) e mastigação de uva-passa (MU) entre os grupos. Podemos concluir que durante o período de uso do front-plateau houve elevação do LDP (reduzindo a sensibilidade à dor) sendo que após a interrupção do tratamento essa variável retornou às condições iniciais; Na EMG foi observado diminuição do estímulo elétrico para padrões posturais de LD, LE e MU. Porém a FMM não foi modificada durante a utilização do dispositivo. / Orofacial pain comprises all pains involving the soft and mineralized tissues of the oral cavity and face, it can be felt in the region of the head and/or neck. The etiology of temporomandibular dysfunction (TMD) is multifactorial. Its defined as musculoskeletal disorders that affect the stomatognathic system, the masticatory muscles and/or associated structures. A very prevalent dysfunction is myofascial pain. Front-plateau is an acrylic resin device installed in the anterior superior teeth, which separates the posterior teeth, providing neuromuscular deprogramming. The purpose of this study was to assess the electromyographic activity, the pain threshold at the temporal and masseter muscles, and the maximum molar bite strength of participants with myofascial pain, before and after the installation of the front-plateau. Participants were recruited and cared at the FORP-USP DAPE Orofacial Pain Clinic. Twenty two women between 20 and 60 years old were evaluated. The participants were initially submitted to electromyography (EMG) tests, MyoSystem-Br1 electromyograph, pressure pain threshold (PPT), Kratos® algometer, and maximal molar bite force (MMB), Kratos® IDDK dynamometer. Two groups were formed, in group 1 (G1) 11 participants used the front-plateau for seven days, 16 hours on the first three days and for eight hours on the next four days, and treatment was stopped after this period. Group 2 (G2), with 11 participants, started the treatment identical to G1 and after seven days they continued using the front-plateau for eight hours daily for another three weeks, totaling one month of use. After treatment, participants from both groups were reassessed four weeks after the first evaluation. The data were analyzed using R software (R® Foundation for Statistical Computing, Austria). The real or transformed values of the variables were compared between the treatments, evaluation days and their interaction by the Analysis of Variance (ANOVA) in an inter randomized design with repeated measures in time. For the variables that presented statistical difference, the means were compared by Tukey\'s post-test (p <0.05) and the data presented as the mean ± standard error (SE). A statistically significant value was found in all the variables analyzed by the algometer. There was a decrease in pain sensitivity and an increase in the pressure pain threshold (PPT) in all muscles analyzed. There was no statistically significant change in the maximum bite force during the period of use of the front-plateau. In electromyography, significant values were found in the postural patterns of right laterality (RL) and left laterality (LL) and chewing of raisins (CR). We can conclude that during the period of use of the front-plateau there was elevation of the PPT (reducing the sensitivity to pain) returning to the initial conditions after removal of the device; It was observed a decrease in the electrical stimulus for postural patterns of RL, LL and CR. However, the MMB was not modified during the use of the device.

O Diabetes mellitus (DM) é o transtorno endócrino mais comum e afeta 6% da população mundial. A neuropatia diabética é uma das complicações do DM e acomete até 60% dos doentes diabéticos. Este é um estudo descritivo que teve como objetivo avaliar as condições odontológicas e a prevalência da ardência bucal nos doentes diabéticos tipo 2 com neuropatia diabética. Foram utilizados os seguintes instrumentos de avaliação: exame sensitivo padronizado da face (algiometria), questionário RDC/TMD eixos 1 e 2, (critérios de diagnóstico em pesquisa) para o diagnóstico de disfunção temporomandibular (DTM), protocolo de avaliação de dor orofacial (EDOF-HC), questionário McGill para avaliação de dor e exame periodontal (IS índice de sangramento, PCS profundidade clínica de sondagem, PCI profundidade clínica de inserção). A prevalência de dor orofacial foi 55,2% e de ardor bucal foi 17,2%. Os valores de glicemia em jejum e HbA1c apresentaram-se acima dos valores normais. Dos doentes avaliados, 44,8% eram totalmente desdentados, 41,2% dos doentes apresentaram doença periodontal avançada, prevalência de dor miofascial mastigatória foi 31%. Traços de depressão moderada e grave e de sintomas físicos inespecíficos moderados e graves foram encontrados em 51,7% dos doentes, de incapacidade baixa e moderada em 37,9%. Observou-se comprometimento da sensibilidade dolorosa em V2 lado D (p=0,007), correlacionada com os valores de HbA1c. / Diabetes mellitus (DM) is one of the most common metabolic diseases affecting 6% of the world population. Diabetic neuropathy is one of DM complications and it affects up to 60% of diabetic patients. This descriptive study aimed to evaluate the dental characteristics and burning mouth prevalence of type 2 DM patients. The following instruments were used: pain sensory test, RDC/TMD questionnaire axis 1 and 2 (research diagnostic criteria for temporomandibular disorders), EDOF-HC protocol (for orofacial pain), Mcgills pain questionnaire and periodontal evaluation (bleeding index, clinical probing depth, clinical probing insertion). Orofacial pain was found in 55,2% of the patients, burning mouth was found in 17,2%. Fasting blood glucose and HbA1c levels were found to be higher than the recommended. 44,8% of the patients were totally edentulous, severe periodontal disease prevalence was 41,2%. Masticatory myofascial pain was found in 31% of the evaluated patients. Traces of severe and moderate depression and severe and moderate nonspecific physical symptoms were found in 51,7% of the patients; moderate and low disability in 37,9%. There was significative difference in the algometry values of the V2 right side compared to the left side and to the study group (p=0,007), with positive correlation with the increased values of the HbA1c.