Choi Kup Sze. / "June 2004." / Thesis (Ph.D.)--Chinese University of Hong Kong, 2004. / Includes bibliographical references (p. 122-127). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Electronic reproduction. Ann Arbor, MI : ProQuest Information and Learning Company, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Mode of access: World Wide Web. / Abstracts in English and Chinese.

As a good and competent surgical simulator, it should provide surgeons with visual, tactile and behavioral illusion of reality. In literature, methods for object deformation range from non-physically based models to physically based models. Early works of non-physically based models focused on pure geometrical models that were originally employed in computer-aided design. These methods could be used to produce vivid deformable effects in computer animation. However, the soft tissue simulation in surgical applications requires more realistic models based on physical properties of human tissues. As a result, the mass-spring model and the finite element model have become the most popular representations for deformable organs in surgical simulation. Our research focuses on the real-time soft tissue deformable model based on the finite element method for surgical application. / Extended from the hybrid condensed finite element model, an interactive hybrid condensed model with hardware acceleration by the graphics processing unit (GPU) is proposed. Two methods are developed in order to map the data onto the GPU in accordance with the application data structure. The performance of the primary calculation task in the solver is enhanced. Furthermore, an improved scheme is presented to conduct the newly applied forces induced by dragging or poking operations in the non-operational region. / In the thesis, new approaches to establish a physically based model for soft tissue deformation and cutting in virtual-reality-based simulators are proposed. A deformable model, called the hybrid condensed finite element model, based on the volumetric finite element method is presented. By this method, three-dimensional organs can be represented as tetrahedral meshes, divided into two regions: the operational region and the non-operational one. Different methods treat the regions with different properties in order to balance the computational time and the level of the simulation realism. The condensation technique is applied to only involve the calculation of the surface nodes in the non-operational region while the fully calculation of the volumetric deformation is processed in the operational part. This model guarantees the smooth simulation of cutting operation with the exact cutting path when users manipulate a virtual scalpel. Moreover, we discuss the relevant aspects on what affect the efficiency of implementing the finite element method, as well as the issues considered for choosing the effective solving method to our problem. Three numerical methods have been examined in our model. / Surgical simulator, which benefits from virtual reality techniques, presents a realistic and feasible approach to train inexperienced surgeons within a safe environment. It plays more and more important role in medical field and also changes the world of surgical training. Especially, the minimally invasive microsurgery, which offers patients various attractive advantages over the traditional surgery, has been widely used in otolaryngology, gastroenterology, gynecology and neurology in the last two decades. / Through the combination of these approaches, a physically based model which allows users to freely perform the soft tissue cutting and detecting, such as poking or dragging operations, with soft tissue deformation is achieved in real-time. / Wu Wen. / "August 2006." / Adviser: Pheng Ann Heng. / Source: Dissertation Abstracts International, Volume: 68-03, Section: B, page: 1745. / Thesis (Ph.D.)--Chinese University of Hong Kong, 2006. / Includes bibliographical references (p. 112-127). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Electronic reproduction. [Ann Arbor, MI] : ProQuest Information and Learning, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Abstracts in English and Chinese. / School code: 1307.

by Lau Wan Yee, Joseph. / Thesis (M.D.)--Chinese University of Hong Kong, 1995. / Includes bibliographical references (leaves 145-189). / Title Page --- p.1 / Dedication --- p.2 / Table of Contents --- p.3 / Hypotheses --- p.7 / Precis to the thesis --- p.8 / List of Publications of my research work used in this thesis --- p.19 / List of Figures --- p.25 / List of Tables --- p.26 / Acknowledgments --- p.27 / Statement of Originality --- p.28 / Chapter PART I --- HISTORICAL REVIEW --- p.30 / Chapter Chapter 1 --- History of Endoscopic and Laparoscopic Surgery --- p.31 / Chapter 1.1 --- History of Endoscopic Surgery --- p.31 / Chapter 1.2 --- History of Documentation of Endoscopic and Laparoscopic Surgery --- p.38 / Chapter 1.3 --- History of Laparoscopic Surgery --- p.39 / Chapter 1.4 --- The future of Endoscopic and Laparoscopic Surgery --- p.52 / Chapter Chapter 2 --- History of Perforated Peptic Ulcer --- p.53 / Chapter PART II --- SIZE OF THE PROBLEM --- p.57 / Chapter Chapter 1 --- Incidence of Feptic Ulcer in Different Parts of The World --- p.58 / Chapter Chapter 2 --- Incidence of Peptic Ulcer in Hong Kong 1970 -1993 --- p.60 / Chapter Chapter 3 --- Incidence of Perforated Peptic Ulcer --- p.70 / Chapter 3.1 --- Incidence of Perforated Peptic Ulcer in Different Parts of The World --- p.70 / Chapter 3.2 --- Incidence of Perforated Peptic Ulcer in Hong Kong --- p.71 / Chapter 3.3 --- "Incidence of Perforated Peptic Ulcer in Prince of Wales Hospital, Hong Kong" --- p.71 / Chapter PART III --- CURRENT TREATMENT OF PERFORATED PEPTIC ULCER --- p.74 / Chapter Chapter 1 --- Recent Developments in Treatment of Uncomplicated Peptic Ulcer --- p.75 / Chapter Chapter 2 --- My Contributions to the Medical Treatment of Uncomplicated Peptic Ulcer --- p.78 / Chapter Chapter 3 --- Review on Current Treatment of Perforated Peptic Ulcer --- p.79 / Chapter 3.1 --- Introduction --- p.79 / Chapter 3.2 --- Currently Available Treatment Options --- p.80 / Chapter 3.2.1 --- Perforated Duodenal Ulcer --- p.81 / Chapter [A] --- Nonoperative Treatment --- p.81 / Chapter [B] --- Laparotomy and patch repair --- p.83 / Chapter [C] --- Definitive Ulcer Surgery --- p.84 / Chapter [D] --- Laparoscopic Treatment --- p.87 / Chapter 3.2.2 --- Perforated Gastric Ulcer --- p.89 / Chapter PART IV --- DEVELOPMENT OF LAPAROSCOPIC REPAIR OF PERFORATED PEPTIC ULCER IN OUR CENTRE --- p.91 / Chapter Chapter 1 --- Development of the Technique of Laparoscopic Suture Repair of Perforated Peptic Ulcer --- p.92 / Chapter 1.1 --- Surgical Technique --- p.93 / Chapter 1.2 --- Initial Results of Laparoscopic Suture Repair --- p.95 / Chapter Chapter 2 --- Development of the Technique of Laparoscopic Sutureless Repair of Perforated Peptic Ulcer --- p.98 / Chapter 2.1 --- Animal Studies --- p.98 / Chapter [A] --- Pilot Animal Study --- p.99 / Chapter [B] --- Mortality Rate on Different Methods of Repair of the Perforations --- p.100 / Chapter [C] --- Strength of the Repair Site by Studying the Bursting Pressure --- p.103 / Chapter [D] --- Detailed Histological Study --- p.108 / Chapter 2.2 --- Clinical Studies --- p.111 / Chapter [A] --- Surgical technique of Laparoscopic Sutureless Repair --- p.113 / Chapter [B] --- Initial Results of Laparoscopic Sutureless Repair --- p.114 / Chapter PART V --- TESTING THE HYPOTHESES OF THIS THESIS --- p.117 / Chapter Chapter 1 --- A Non-randomised Clinical Study --- p.119 / Chapter Chapter 2 --- A Randomised Clinical Study --- p.126 / Chapter PART VI --- CONCLUSIONS --- p.140 / Chapter PART VII --- THE FUTURE OF LAPAROSCOPIC REPAIR OF PERFORATED PEPTIC ULCER --- p.142 / Chapter PART VIII --- REFERENCES --- p.145 / References to the Precis --- p.146 / References to Part I Chapter 1 --- p.147 / References to Part I Chapter2 --- p.157 / References to Part II --- p.162 / References to Part III --- p.168 / References to Part IV --- p.183 / References to Part V --- p.186 / References to Part VII --- p.189 / APPENDIX I BRIEF SUMMARY OF MY CONTRIBUTIONS TO THE MEDICAL TREATMENT OF UNCOMPLICATED PEPTIC ULCER --- p.190

Submitted by Marcelo Rodella Bettanim null (marcelobettanim@hotmail.com) on 2017-02-01T23:02:17Z No. of bitstreams: 2 Dissertação Mestrado.pdf: 1589844 bytes, checksum: e77f0b869b86e9b1cd2f8e01ee7a695b (MD5) Dissertação Mestrado.pdf: 1589844 bytes, checksum: e77f0b869b86e9b1cd2f8e01ee7a695b (MD5) / Rejected by LUIZA DE MENEZES ROMANETTO (luizamenezes@reitoria.unesp.br), reason: Solicitamos que realize uma nova submissão seguindo as orientações abaixo: Foram submetidos 2 arquivos PDF’s, apenas 1 arquivo deve ser submetido. O arquivo PDF não deve estar protegido e a dissertação/tese deve estar em um único arquivo, inclusive os apêndices e anexos, se houver. Corrija estas informações e realize uma nova submissão contendo o arquivo correto. Agradecemos a compreensão. on 2017-02-06T13:01:12Z (GMT) / Submitted by Marcelo Rodella Bettanim null (marcelobettanim@hotmail.com) on 2017-02-07T00:32:44Z No. of bitstreams: 1 Dissertação Mestrado.pdf: 1589844 bytes, checksum: e77f0b869b86e9b1cd2f8e01ee7a695b (MD5) / Approved for entry into archive by LUIZA DE MENEZES ROMANETTO (luizamenezes@reitoria.unesp.br) on 2017-02-09T15:32:42Z (GMT) No. of bitstreams: 1 bettanim_mr_me_rcla.pdf: 1589844 bytes, checksum: e77f0b869b86e9b1cd2f8e01ee7a695b (MD5) / Made available in DSpace on 2017-02-09T15:32:42Z (GMT). No. of bitstreams: 1 bettanim_mr_me_rcla.pdf: 1589844 bytes, checksum: e77f0b869b86e9b1cd2f8e01ee7a695b (MD5) Previous issue date: 2016-12-13 / Este estudo objetivou analisar os procedimentos de trabalho de treinadores de futebol de categorias sub-15 de clubes esportivos paulistas através da identificação do processo de formação dos treinadores e análise de quais procedimentos de trabalho os treinadores utilizam para atingir os objetivos de formação esportiva e humana de seus atletas. A metodologia caracteriza-se como uma pesquisa descritiva de abordagem qualitativa, sendo utilizada como fonte de dados a revisão de literatura acerca do assunto pesquisado, leis que regulamentam o atual exercício da atividade de treinador de futebol no Brasil e a interpretação das informações advindas de um questionário semiestruturado e posterior aprofundamento das informações coletadas através de uma entrevista semiestruturada, sob a técnica de análise do conteúdo. Os resultados revelaram que o perfil dos treinadores é constituído pela prevalência da formação acadêmica de licenciado e bacharel em Educação Física de forma concomitante, sendo que as competências que fundamentam os procedimentos de trabalho são adquiridas através do conhecimento científico, socioeducativo, disciplinar e artesanal. Como procedimentos de trabalho na seleção esportiva de seus atletas destacam-se a avaliação técnica, comportamental, tática, física e indicação externa (com base no saber fazer, método de tentativa e erro). Como procedimentos de rendimento esportivo destacam-se a preparação tática, preparação técnica, preparação física, conduta disciplinar, estímulo cognitivo e abordagem psicológica, sendo que para os procedimentos de formação humana, destacam-se a socialização através do diálogo, a orientação disciplinar, a orientação educacional, a formação cidadã ética-moral e a valorização dos valores esportivos universais. O estudo concluiu que os treinadores não utilizam procedimentos de trabalho pautados em critérios objetivos e científicos aparentes em suas ações procedimentais, indicando apenas que tais ações baseiam-se pela observação subjetiva. Apesar dos treinadores compreenderem a relevância do conhecimento científico em suas ações procedimentais, as informações também indicam a importância do conhecimento prático para exercer a atividade de treinador de futebol. Sugere-se que mais estudos acerca dessa temática sejam desenvolvidos para aprofundar as práticas utilizadas pelos treinadores no sentido de revelar a construção de procedimentos de trabalho baseados em parâmetros científicos / This study aimed to analyze the working procedures soccer coaches categories sub-15 São Paulo sports clubs by identifying the training of trainers process and analysis which work procedures trainers use to achieve the sporting and human development objectives of their athletes. The methodology is characterized as a descriptive qualitative approach, being used as a data source literature review on the subject researched, laws governing the current year the football coach of activity in Brazil and the interpretation of the information coming from a semi-structured questionnaire and further development of the information collected through a semi-structured interview, in the analysis of technical content. The results showed that the profile of coaches consists of the prevalence of licensed academic background and degree in Physical Education concomitantly, and the skills that underlie the working procedures are acquired through scientific, socio-educational, disciplinary and traditional knowledge. As working procedures in sports selection of their athletes stand out the technical, behavioral, tactical, physical and external indication (based on know-how, trial and error). As a sports performance procedures include the tactical preparation, technical preparation, physical preparation, discipline, behavior, cognitive stimulation and psychological approach, and for the procedures of human, socialization stand out through dialogue, disciplinary orientation, educational, ethical-moral civic education and appreciation of universal sporting values. The study concluded that the coaches do not use working procedures guided by objective criteria and apparent scientific in its procedural actions, indicating only that such actions are based on the observation subjective. Despite the coaches understand the importance of scientific knowledge in its procedural actions, the information also indicates the importance of practical knowledge to practice football coach activity. It is suggested that more studies on this subject are developed to deepen the practices used by coaches in order to reveal the construction work procedures based on scientific parameters.

Orientador: Alessandro Lia Mondelli / Resumo: A infecção de sítio cirúrgico é a complicação mais frequente em pacientes cirúrgicos e sua incidência pode ser diminuída com a profilaxia antimicrobiana realizada adequadamente. Sua importância na prevenção dessa infecção tem se tornado um tema relevante e emergencial para uma assistência adequada e segura. Este estudo objetivou avaliar o uso adequado da profilaxia antimicrobiana e a ocorrência de infecção de sítio cirúrgico de acordo com protocolo da Comissão de Controle de Infecção Relacionada à Assistência à Saúde (CCIRAS). Trata-se de um estudo de coorte, prospectivo, com seguimento de trinta dias em hospital de ensino do interior de São Paulo, Brasil. Para elegibilidade da amostra foram selecionados pacientes acima de 18 anos submetidos a cirurgias de todas as especialidades cirúrgicas, sejam eletivas e de urgência/emergência, que receberam profilaxia antimicrobiana. A coleta de dados foi através de software desenvolvido para este fim que comparou a profilaxia antimicrobiana realizada com a preconização do protocolo instituicional, identificando os acertos e inadequações para cada item avaliado. A infecção de sítio cirúrgico foi avaliada pela CCIRAS do hospital, a qual realiza a vigilância dos pacientes pós-alta através de ligações telefônicas. A amostra constituiu de 415 pacientes com cirurgias principalmente eletivas. A conformidade com todos os quesitos avaliados da profilaxia antimicrobiana foi de 1,7%. Verificamos que a cada inadequação da profilaxia antimicrobiana ... (Resumo completo, clicar acesso eletrônico abaixo) / Mestre

This Diploma work is supposed to bring important information concerning the principles of outsourcing of taxable, accountant and wage services. The theoretical - methodical part is specialized on the explanation of the word "outsourcing", its principal, form and historical development. The problematic of advantages and disadvantages is being solved as well as the risks connected. The reasons for realization of outsourcing are being described and also the phases of development of outsourcing project and the mistakes during the implementation are being explained. A definition of outsourcing contract and its main belongings is also a part of this work. There was a concrete outsourcing agency - Auditmax,s.r.o., handling accounting, taxes and wages of external companies, chosen in the practical part. There is an analysis of present state of the agency, an identification of insufficiency and a suggestion of their removal using newly created procedures that would contribute to more efficient provision outsourcing services. The result is a complex of advises and measures that might be used by and outsourcing agency for further development.

CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior / RecÃm-nascidos (RNs) que apresentam funÃÃo pulmonar prejudicada, seja pela prematuridade ou por algum diagnÃstico que interfira no sistema respiratÃrio, necessitam, geralmente, de algum tipo de oxigenoterapia. Objetivou-se avaliar os parÃmetros fisiolÃgicos (FR, FC, pulso e SpO2) na execuÃÃo de alguns procedimentos dolorosos (aspiraÃÃo do TOT/VAS, coleta de gasometria, passagem de cateter central de inserÃÃo perifÃrica-PICC e retirada de curativo) realizados pelos(as) enfermeiros(as) em RNs submetidos à oxigenoterapia em uma Unidade de Terapia Intensiva Neonatal (UTIN). Para tanto, realizou-se um estudo longitudinal do tipo antes e depois, de carÃter quantitativo, em uma UTIN de uma instituiÃÃo pÃblica de referÃncia na cidade de Fortaleza-CearÃ, durante o perÃodo de dezembro de 2008 a junho de 2009. Fizeram parte da amostra 125 RNs com, no mÃnimo, seis horas de vida e internados em leitos de alto risco, que utilizavam alguma forma de oxigenoterapia por um perÃodo mÃnimo de seis horas e que se encontravam clinicamente estÃveis. A coleta de dados efetivou-se por meio da observaÃÃo sistemÃtica e os dados foram registrados em formulÃrios, contemplando algumas variÃveis independentes, tais como os procedimentos dolorosos realizados pelos enfermeiros(as) e algumas variÃveis dependentes, como os parÃmetros fisiolÃgicos de FR, FC, juntos aos visualizados no monitor durante os procedimentos (pulso, SpO2). AlÃm destas variÃveis, estudou-se tambÃm as caracterÃsticas de base dos RNs quanto Ãs condiÃÃes de nascimento (peso ao nascer, sexo, tipo de parto, Apgar, Capurro) e durante a internaÃÃo na UTIN (data e horÃrio da internaÃÃo, data do inÃcio da utilizaÃÃo e modalidade de oxigenoterapia instalada ao ser admitido na UTIN, modalidade de oxigenoterapia e peso no momento da coleta, acomodaÃÃo, dieta, medicaÃÃo). Tais dados foram adquiridos por meio do prontuÃrio, com o propÃsito de correlacionÃ-los com as referidas variÃveis. Os resultados mostraram que 92,8% dos RNs eram prÃ-termo e 7,3%, a termo, sendo que 56,8% nasceram de parto cesÃrea e 43,2%, de parto vaginal. Quanto ao peso dos bebÃs estudados, 92,0% pesaram abaixo de 2500g e apenas 7,2%, acima de 2500g. As hipÃteses diagnÃsticas mais presentes foram prematuridade (93,6%) e SÃndrome do Desconforto RespiratÃrio-SDR, (52,8%). Ao avaliar o conjunto de parÃmetros fisiolÃgicos para os quatro procedimentos pesquisados, houve alteraÃÃes (p<0,05) de FR e FC para os RNs em Oxi-Hood e CPAP e de pulso (p<0,05) para os RNs em Oxi-Hood, CPAP e VM, sendo a SpO2 o Ãnico parÃmetro que nÃo sofreu variaÃÃo significativa (p>0,05) na prÃtica de aspiraÃÃo do TOT/VAS. Na gasometria, houve variaÃÃes (p<0,05) de todos os parÃmetros fisiolÃgicos, porÃm, para tal procedimento, as alteraÃÃes foram diferentes em cada modalidade de oxigenoterapia, ocorrendo variaÃÃes de FC, pulso e SpO2 nos RN em Oxi-Hood e alteraÃÃes de FR e pulso nos RNs em VM. Entretanto, na passagem de cateter percutÃneo e na retirada de curativo, nÃo houve alteraÃÃes estatisticamente significantes (p>0,05). PropÃe-se aos enfermeiros(as) desenvolverem intervenÃÃes que possam manter as variaÃÃes dos parÃmetros de FR, FC, pulso e SpO2 dentro da faixa de normalidade na execuÃÃo destes procedimentos. / Newborn infants that have impaired lung function because of prematurity or any other diagnosis that interferes in the respiratory system, usually need some type of oxigenotherapy. The objectives of this study were to evaluate physiological parameters (RR, HR, Pulse, SpO2) in neonates submitted to oxigenotherapy in a Neonatal Intensive Care Unit (NICU) during the execution of some painful procedures carried out by nurses (orotracheal suction, upper airway suction, blood collectium to gasometry, insertion of a Peripherally Inserted Central Catheter â PICC - and withdrawing of curative). For this purpose, it was developed a before and after longitudinal and quantitative study in a Neonatal Intensive Care Unit of a public institution of reference in the city of Fortaleza-Ceara, in the period of December 2008 to June 2009. The sample was composed of 125 clinically stable newborns hospitalized in high-risk beds with at least six hours of life, and submitted to some type of oxigenotherapy for at least six hours. The data collecting was accomplished by systematic observation and the data were recorded in research forms that contained some independent variables, such as painful procedures carried out by nurses and some dependent variables such as the physiological parameters, like RR, HR and others that were visualized in the cardiac monitor during the procedures (pulse, SpO2). Additionally to these variables, it was studied both characteristics of the newborns regarding the birth conditions (birth weight, gender, type of labour, Apgar score, capurro) and regarding the period of hospitalization in the NICU (date and time of hospitalization, date and type of oxigenotherapy when the baby was admitted in the NICU, oxigenotheray modality and newborn weight at the time of the data collection, accommodation, diet and medication). These data were obtained through the medical charts, with the purpose of correlating them to those variables. The results showed that 92,8% of the neonates were preterm infants and 7,3% were term infants. Regarding the type of labor, 56,8% of the babies were delivered by caesarean section and 43,2% of them born by vaginal labor. According to the weight of the babies under the study, 92,0% weighted below 2500g while only 7,2% were above 2500g. The most common diagnostic hypotheses founded were prematurity (93,6%) and Respiratory Distress Syndrome - RDS (52,8%). The evaluation of the physiological parameters of the four procedures accessed in this study showed some variations (p<0,05) of RR and HR in the newborns using hood and CPAP, and variation of pulse (p<0,05) for the newborns in hood, CPAP and MV; however, the SpO2 was the only parameter that did not suffer any significant variation (p>0,05) regarding the suction of either orotracheal tube or upper airway. Concerning the gasometry, variations were found (p<0,05) in all physiological parameters; nevertheless, the alterations related to this procedure were different for each oxigenotherapy modality, occurring changes in HR, pulse and SpO2 in newborn using hood, and alterations in RR and pulse in neonates under MV; however, regarding the insertion of a PICC and the withdrawing of curative, no statistically significance alterations were found (p>0,05). It is proposed to the nurses to develop interventions that can keep the variations of the parameters of RR, HR, pulse and SpO2 in normal levels during the execution of these procedures.

nÃo hà / The present study tries to expose a statistical analysis of the data collected from the Comptroller General of Discipline relating to disciplinary procedures applied to military police. In this sense, aims to qualitatively evaluate the statistical results obtained. The work developed correiÃÃo is critical to the performance of military police, considering, discouraging illicit acts by security agents and ensure a welcoming society and security against misconduct of security agents. In our study object the best option was a regression model censored tobit model that was the best fit to the study of variables collected. In the end it describes a qualitative analysis of the results for the variables found. / O presente estudo procura expor uma anÃlise estatÃstica dos dados coletados da Controladoria Geral de Disciplina, referente aos procedimentos disciplinares aplicados aos policiais militares. Neste sentido, visa avaliar qualitativamente os resultados estatÃsticos obtidos. O trabalho de correiÃÃo desenvolvido à de fundamental importÃncia para o desempenho dos policiais militares, haja vista, desencorajar a prÃtica de atos ilÃcitos por agentes de seguranÃa e garantir a sociedade um acolhimento e seguranÃa contra desvios de conduta dos agentes de seguranÃa. Na busca por alcanÃar o objetivo deste estudo, a melhor opÃÃo foi um modelo de regressÃo censurada, o modelo tobit, que foi o que melhor se adequou ao estudo das variÃveis colhidas. No final buscou-se descrever uma anÃlise qualitativa dos resultados referentes Ãs variÃveis encontradas.

A sífilis é uma doença infecciosa, cujo agente etiológico é o Treponema pallidum. Pode ser transmitida sexualmente ou verticalmente, via placenta. Seus estágios variam entre sífilis primária, sífilis secundária, sífilis latente e sífilis congênita. Dentre os diagnósticos mais eficazes, encontram-se os testes sorológicos, porém os falsos positivos e falsos negativos no estágio primário levam à procura de uma forma mais eficaz de se determinar, precocemente, a doença. Além disso, por várias razões, nem sempre o profissional clínico suspeita das lesões presentes na mucosa oral, cogitando de outras hipóteses diagnósticas. O objetivo deste trabalho foi avaliar imuno-histoquimicamente e histoquimicamente lesões bucais biopsiadas cujo aspecto histológico levou à suspeita de sífilis, buscando identificar os microorganismos, bem como correlacionar o quadro sorológico quando positivo. Para o estudo foram incluídas 34 lesões suspeitas de sífilis, que foram submetidas à reação imuno-histoquímica com o anticorpo anti-treponema e técnica histoquímica de coloração pela prata. Dos 34 casos avaliados 13 foram positivos para o anticorpo anti-treponema, todos posteriormente diagnosticados como sífilis secundária, com positividade sorológica, exceto por um caso em que a sorologia não foi realizada. Quando se comparou os métodos de diagnóstico, a técnica de coloração por prata obteve sensibilidade de 46,15% e a de imuno-histoquímica foi de 92,3%. Os aspectos histológicos variaram em um grande número de achados, dentre eles: intensa exocitose, infiltrado inflamatório predominantemente plasmocitário (justaepitelial e perivascular), áreas de ulceração, epitélio paraqueratinizado, edema, espongiose e hiperplasia epitelial. A marcação imuno-histoquímica dos treponemas foi, principalmente, epitelial (61,5%) e esse método se mostrou um meio de diagnóstico rápido, simples e eficiente no diagnóstico de lesões orais de Sífilis. / Syphilis is an infectious disease, whose etiologic agent is Treponema pallidum. It can be transmitted sexually or vertically via the placenta. Its stages include primary syphilis, secondary syphilis, latent syphilis and congenital syphilis. Among the diagnoses most effective are the serological tests, but false positives and false negatives in the primary stage lead to demand for a more effective way to determine the disease earlier. In addition, for various reasons, not always the professional clinical suspicion of lesions present in the oral mucosa, thinking in other possible diagnoses. The objective of this study was to identify microorganisms and set the best way forward to a diagnostic framework confirmed positive serology. The results for syphilis lesions in the oral mucosa corresponded to 13 cases, all of secondary iinjuries,with positive serology for syphilis and in only one of them serology had not been held. In a comparison of diagnostic methods, the technique of silver staining achieved sensitivity of 46.15% and immunohistochemistry was 92.3%. The histological features varied in a large number of findings, including: intense exocytosis, inflammatory infiltrate, predominantly plasmacytic (banda-like and infiltrate perivascular), areas of ulceration, parakeratinized epithelium, edema, spongiosis and epithelial hyperplasia. The immunohistochemical staining of treponemes was mainly epithelial (61.5%) and this method was a rapid, simple and efficient means in the diagnosis of oral lesions of syphilis.

Neste trabalho foram estudados os efeitos da radiação ionizante (gama) em mangas para exportação, simulando a etapa de acondicionamento da fruta durante o seu transporte, através da refrigeração em câmara fria. Em uma primeira etapa foram analisadas perda de peso, pH, acidez titulável, teor de sólidos solúveis, textura e decomposição. Posteriormente, realizaram-se análises sensoriais (alterações de cor, odor, sabor, textura). Os ensaios foram realizados em dois estádios de maturação das frutas, ou seja, 2 e 3, com o propósito de se estudar o melhor ponto de colheita para a melhor dosagem de irradiação. Os resultados revelam que o tratamento da manga Tommy Atkins na dose de 0,75 kGy foi significativo, juntamente com a fruta no estádio 2, para o retardo do amadurecimento e consequente ganho de tempo para a exportação. / It had been studied the effect of the ionizing radiation (gamma) in mangoes for exportation, simulating the stage of preservation of the fruit during its transport, through the refrigeration in cold chamber. In a first stage they had been analyzed through loss of weight, pH, treatable acidity, soluble solid, texture and decomposition. Later, sensorial analyses had been become fulfilled (alterations of color, odor, flavor, texture). The assays had been carried through in two stadiums of maturation of the fruits, that is, 2 and 3, with the intention of studying optimum point of harvest for the best dosage of irradiation. The results disclose together that the treatment of the mangoes Tommy Atkins in the dose of 0,75 kGy was significant, with the fruit in stadium 2, for the retardation of the matureness and consequent profit of time for the exportation.