京都大学 / 0048 / 新制・課程博士 / 博士(社会健康医学) / 甲第21701号 / 社医博第92号 / 新制||社医||10(附属図書館) / 京都大学大学院医学研究科社会健康医学系専攻 / (主査)教授 平井 豊博, 教授 小西 靖彦, 教授 伊達 洋至 / 学位規則第4条第1項該当 / Doctor of Public Health / Kyoto University / DFAM

付記する学位プログラム名: デザイン学大学院連携プログラム / 京都大学 / 0048 / 新制・課程博士 / 博士(情報学) / 甲第22097号 / 情博第707号 / 新制||情||121(附属図書館) / 京都大学大学院情報学研究科社会情報学専攻 / (主査)教授 黒田 知宏, 教授 吉川 正俊, 教授 矢守 克也 / 学位規則第4条第1項該当 / Doctor of Informatics / Kyoto University / DFAM

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The author of the thesis deals with the issue of the short-term and medium-term rehabilitation plan for selected sewer netwotk. Resolved area for this work is the town of Břeclav. The Contracting Authority selected the area of interest that falls within the cadastral territory of Břeclav - Poštorná. The aim of the thesis is to elaborate a short-term and medium-term strategy of remediation of a selected part of the sewerage network for the need of a recovery plan.

INTRODUCTION: Polycystic Ovary Syndrome (PCOS) is the most common endocrinopathy causing infertility in women of reproductive age. According to the Rotterdam criteria, a PCOS diagnosis should be given if at least two of the following are met: 1) hyperandrogenism; 2) oligo-anovulation; and 3) polycystic ovarian morphology. Previous studies analyzing the prevalence of PCOS have done so in unselected and clinical populations but few studies have attempted to characterize the syndrome and its long-term outcomes within Electronic Health Records using International Classification of Disease (ICD) codes. OBJECTIVES: With a hospital-based electronic health record dataset, this thesis seeks to: (1) characterize PCOS in reproductively aged women (18-34) using the diagnostic codes (ICD-9 and ICD-10) versus the Rotterdam criteria, (2) determine the prevalence of metabolic syndrome (MetS), Type 2 Diabetes, and cardiac events in women above age 35, (3) determine age of diagnosis for MetS and time to diagnosis of MetS. METHODS: The following 3 cohorts were queried on the Research Patient Data Registry (RPDR): 1) patients aged 18-34 with classic PCOS (phenotype A and B) but without an ICD diagnosis for PCOS, 2) patients aged 18-34 with a PCOS ICD-9/10 diagnosis and 3) patients above age 35 with a history or current diagnosis of PCOS. Their electronic health records (between January 1 , 2003 and December 31 , 2020) were ascertained from 9 Mass General Brigham institutions after IRB approval and analyzed on Software for Statistics and Data Science (STATA). RESULTS: Overall, RPDR identified 12,669 patients aged 18-34 who fit the Rotterdam criteria (under multiple phenotypes), 4646 of which had classic PCOS but lacked an ICD- 9/10 code for PCOS. RPDR also identified 9341 women aged 35 and above with a past or current diagnosis of PCOS. Hispanics/Latinas (18-34) were two times more likely to be undiagnosed when compared to Non-Hispanic Whites (OR: 2.25, 95% CI: 1.98-2.56). The prevalence of MetS, specified by a diagnostic code (277.7 or E88.81), and other cardiac conditions in women above age 35 were considerably lower than those found in the current literature. CONCLUSION: Databases such as RPDR allow for a detailed analysis of patient demographics, labs, procedures and diagnoses. Additionally, it allows for larger cohorts of patients matching more specific criteria to be ascertained. Future studies should compare the prevalence of individual features of MetS by ICD codes and analyze the cardiology reports to determine if the events are being reported but not codified. / 2023-11-30

There is a need for a serial communication testing tool when software or hardware developers have to solve serial communication problems. This tool must accurately catch and record the whole communication. Some type of timestamps in the record is necessary for future analysis. This diploma thesis deals with programming a serial communication monitoring equipment software with the possibility of the insertion of timestamps. Possible timestamps types and inserting methods are also discussed. The programmed monitoring software for the FOX Board hardware platform is able to catch and record the serial communication at RS232 ports and add timestamps to the record in accordance to three independent rules. The record is saved to a standard USB flash drive.

This diploma thesis deals with design and implementation of NetFlow data manipulation tool. It contains analysis of IP Flow network monitoring, description of nfdump tool and format of Netflow v9 records saved by nfdump. The focus of this application interface lies in effective manipulation with NetFlow records.

In South Africa, as in most jurisdictions which profess to be based on an open and democratic society based on human dignity, equality and freedom, the right against compelled self-incrimination is a guaranteed Constitutional right. This study is prompted by the realization that the right against self-incrimination is being undermined and eroded by an aspect of South Africa’s bail laws. The current study addresses the constitutional validity of section 60(11B)(c) of the Criminal Procedure Act 51 of 1977 in so far as it allows for the admission of incriminating evidence at trial, in contravention of the accused’s right against self-incrimination, which incriminatory evidence was tendered by the applicant during a bail application in circumstances where the applicant was compelled to prove that he would be acquitted at trial where reliance is placed on a weak State’s case in proving exceptional circumstances in compliance with section 60(11)(a) of the Criminal Procedure Act 51 of 1977. Whilst section 60(11B)(c) of the Criminal Procedure Act 51 of 1977 is undoubtedly aimed at combatting crime, the pre-occupation with crime control measures threatens to undermine individual liberty and poses a threat to our Constitutional project of building a human rights culture. I advance an argument which supports the view that section 60(11B)(c) of the Criminal Procedure Act 51 of 1977 is unconstitutional, in the above context, in that it infringes upon the accused’s right against compelled self-incrimination at trial and does not amount to a justifiable limitation on the rights of an accused in an open and democratic society based on human dignity, equality and freedom. I also advance an alternative legal remedy aimed at fulfilling the initial mischief which Section 60(11B)(c) of the Criminal Procedure Act 51 of 1977 was designed to prevent in order to bring the section in line with the Constitution and a rights-based society. / Mini Dissertation (LLM)--University of Pretoria, 2017. / Procedural Law / LLM / Unrestricted

PhD (African Studies / Centre for African Studies / This study explored the implications of Act 12 of 2012 on the establishment of indigenous languages within the ambit of the Constitution of the Republic of South Africa’s Act 108 of 1996 on the use of English and Afrikaans Languages only in the Vhembe District criminal court proceedings. The establishment of the Indigenous Language Courts for the purpose of using indigenous languages, namely Tshivenda, Xitsonga and Sepedi as languages of court was the main objective of this study. This study investigated (a) whether present legally-recognised methods on the use of English and Afrikaans only in criminal court proceedings give effect to the right to a fair trial and (b) what are the implications of the Use of Official Languages Act on the use of English and Afrikaans only in the Vhembe District multilingual criminal courtrooms. This was accomplished through qualitative methods of data collection and analysis, namely in-depth personal interviews and textual analysis of the literature and case law review on the phenomenon under investigation. The interviews were conducted with samples of seven categories of participants, namely, the accused persons, the convicted persons, the court officials, court interpreters, the DJ & COND Directors, the PanSALB and one University Centre for African Languages i.e. UCT. Through both methods, it was revealed that the legally enforceable methods that prefer the use of English and Afrikaans as languages of the courts and court records over the accused’s indigenous language or their mother-tongue in the entire trial thereby negating their right to a fair trial, are the provisions of the legislation and the Constitution and their application thereof, as well as legal instructions and culture. It was further revealed that this Act implied the elimination of the use of English and Afrikaans and creates opportunity to the accused’s right to use his or her mother-tongue as one of the indigenous languages in the entire trial thereby affording the accused the right to a fair trial. The study found that the two theories as designed and implemented revealed problems on the ground and helped this research to conclude that these legally enforceable methods created the feeling of unfair treatment amongst the users of the indigenous languages in court. It suggested that the three identified indigenous languages be used as languages of court and of court record.

1 Abstract Charles University in Prague, Faculty of Pharmacy in Hradci Králové Department of: Departmanet of Pharmaceutical technology Consultant: doc. PharmDr. Zdeňka Šklubalová Ph.D. Student: Hana Machutková Title of Thesis: Influence of different types and ratios of microcrystalline cellulose and lactose on physical properties of tablet blends and tablets. In this study, the properties of tablet blends prepared from five different kinds of microcrystalline cellulose (Avicel ® A-101, 102, 105, 112, 200) and three types of lactose in different proportions were evaluated. Moisture content, the bulk and tapped density and the angle of repose were compared for tablet blends. The addition of lactose to the mixtures caused the decrease in the moisture content in the tablet blends. After evaluating the flow properties, the mixtures with suitable characteristics were compacted at compression forces of 8 and 12 kN. The force required to eject the tablet, the table strength, the disintegration time and the friability of the resulting tablets were estimated. The worst compressibility was identified for mixtures with higher concentration of Avicel 105. Due to its very small and fine particles (approximately 20μm) the filling of matrix was not uniform making tablet compression unsuccessful and thus the of uniform...