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Ethical, Legal and Social/Societal Implications (ELSI) of Recall-by-Genotype (RbG) approaches in the Cooperative Health Research in South Tyrol (CHRIS) study on genetic risk factors of Parkinson’s disease (PD)Tschigg, Katharina 21 December 2023 (has links)
Recall-by-genotype (RbG) strategies are bottom-up approaches to conducting targeted follow-up studies or substudies with eligible participants. They use specific genetic information derived from pre-vious genome-wide association studies or whole-genome sequenc-ing enabled by next-generation sequencing. Genetic information may be partially disclosed when certain partici-pants are recalled for RbG studies, and information on the study design and eligibility criteria is provided. These distinguishing pecu-liarities of RbG approaches have ethical, legal, and social/societal implications (ELSI). In this thesis, we present and discuss the results of research on the ELSI aspects of RbG approaches and within the Cooperative Health Research in South Tyrol (CHRIS) studies (RbG1, RbG2) on genetic risk factors of Parkinson's disease (PD). We used various qualitative and quantitative methods, including in-terviews, surveys and focus group discussions (FGD). Thereby, we sought to address the need for qualitative data from diverse stake-holders, including critical voices in the CHRIS research ecosystem, such as participants, researchers, ethics board members, and study assistants, to develop effective recall and communication strategies through a collaborative approach refining the CHRIS RbG policy. The exploration began with a literature review revealing the explicit and implicit ELSI of RbG study designs. It uncovered a consensus on the significant ethical challenges RbG poses while highlighting the diversity in consent models and Return of Research Results (RoRR) policies employed in different research and biobanking con-texts. Then, a secondary analysis of interviews and surveys from a mixed-methods study with CHRIS RbG participants from the RbG pilot study (RbG1) followed. Alongside the second follow-up RbG study (RbG2) study, we then designed a survey, informed by the results of RbG1, to gather further perspectives on their experience of an RbG study, and other fundamental considerations pertinent to en-gagement and communication in RbG studies. Then, to explore the operational and practical aspects of RbG studies, we identified the relevant stakeholders who shape and decide on RbG study designs. Consequently, we designed and conducted FGD to examine stake-holder perspectives on the RbG study design, communication, and disclosure strategies. Further, we collected feedback and views from CHRIS study personnel and coordinators who accompanied the RbG1 and 2 study process. Finally, we conducted a large-scale sur-vey with CHRIS participants to strengthen the conclusions of previ-ous empirical research. This collaborative approach aims to refine the CHRIS RbG policy, develop effective recruitment and commu-nication strategies, and promote transparency. The study's findings underscore the value of personalised engage-ment and sensitive communication through tailored disclosure and communication strategies. Stakeholder views on ELSI in RbG stud-ies reveal diversity, highlighting the need for adaptable approaches aligned with study contexts. Overall, the results suggest that partici-pants are highly interested in receiving information on carrier status on the genetic variations investigated by the RbG study, but views and motivations were heterogeneous. This adds to the complexity of integrating these insights into communication strategies and disclo-sure policies. More research is necessary to investigate the effects of various disclosure strategies, the impact of disclosure on awareness, and how framing affects participants' reception of study-specific information.
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#StandwithPP: An Analysis of Planned Parenthood's Use of FacebookKlever, Abbey L. January 2017 (has links)
No description available.
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Risk Management in Pre-Production of Film Projects : A study on key risk management factors during the pre-production phase in film projectsÖman, Isac, Murry, Isabella January 2024 (has links)
This paper explores the role of risk management during the pre-production phase of film projects. The purpose is to find the key risk management factors in film production and find which actions top management takes in the pre-production phase to mitigate these. To address this, the following research questions are used: (1) What are the key risks associated with film projects, and what actions are taken by top management to mitigate these?Followed by our sub-questions of, (2) How are risks identified in the pre-production of film projects? (3) How does communication and stakeholder engagement contribute to risk mitigation in film projects? (4) Which are the most common and recommended risk mitigation strategies? The central problem addressed in this paper is the lack of a comprehensive understanding of how risk management practices can contribute to mitigating risks in film projects. To explore this issue, we use a qualitative research methodology, including semi-structured interviews with five top management professionals in the film industry. The interviews aimed at gathering in-depth insights into their experiences and practices related to risk management during the pre-production phase. The data collected was analyzed using thematic analysis. Our research identified key risks in film projects and what methods top management uses to identify these risks in pre-production. Furthermore, we present how communication and stakeholder management contribute to risk management in pre- production. Lastly, we provide the most common risk mitigation strategies applied in the film industry. Our findings offer practical recommendations for professionals in the film industry and for up-and-coming producers and directors who want ground pillars to stand on when starting a film project. Furthermore, our findings contribute to the existing risk management literature by focusing on a not-so-well-studied subject, namely risk management, in the film's pre-production phase.
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Environmental sustainability orientation, competitive strategy and financial performanceDanso, A., Adomako, Samuel, Amankwah-Amoah, J., Owusu-Agyei, S., Konadu, R. 2019 February 1918 (has links)
Yes / Extant research has established that environmental sustainability orientation (ESO) has a positive influence on performance outcomes. Nevertheless, several contingencies tend to affect the strength of this relationship. In this study, we draw on natural resource-based theory to introduce competitive strategies as moderators in the ESO-performance nexus. Using time-lagged data obtained from 269 firms in Ghana, this study finds that firms pursuing the differentiation strategy can positively boost performance outcomes with ESO than without differentiation strategy. We also find that firms can use the low-cost or the integrated strategy to get higher impact on performance with ESO respectively. Based on the results, firms in Ghana do not need differentiation strategy in order to boost the effect of ESO on financial performance. Theoretical and practical implications are discussed.
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CEO reputation, quality management and environmental innovation: the roles of stakeholder pressure and resource commitmentKonadu, R., Owusu-Agyei, S., Lartey, T., Danso, A., Adomako, Samuel, Amankwah-Amoah, J. 29 March 2020 (has links)
Yes / In this paper, we examine how and when chief executive offers’ (CEOs’) reputation enhances environmental innovation by considering quality management as a mediating mechanism of this relationship. In addition, we introduce stakeholder pressures (primary and secondary stakeholder pressures) as important contingencies of the relationship between CEOs’ reputation and quality management. Moreover, we test the moderating role of resource commitment on the quality management-environmental innovation relationship. We test our research model using data from a manufacturing industry sample of 217 firms from Ghana. We find that quality management mediates the relationship between reputation and environmental innovation. Moreover, the relationship between CEOs’ reputation and quality management is amplified when levels of both primary and secondary stakeholder pressures are greater. Finally, our findings show that the effect of quality management on environmental innovation is enhanced when resource commitment is greater. Implications for theory and practice are discussed.
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Demystifying Corporate Inertia Towards Transition to Circular Economy: A Management Frame of ReferenceYamoah, F.A., Sivarajah, Uthayasankar, Mahroof, Kamran, González Peña, I. 14 December 2021 (has links)
Yes / We examine corporate inertia towards circularity transition using organisational case studies, observations, and qualitative interviews with business executives. The study explores how the values and beliefs of business leaders and managers promote or inhibit internal and external stakeholder engagement to enable transition to circular business models. We focus on four large UK food companies, conducting interviews with 11 senior managers. Rather than a lack of awareness of the circular economy (CE), the results demonstrate that business leaders are not persuaded by the short-to medium-term business case for a CE. There is misalignment between values and beliefs of business executives and the circularity values and goals of their organisations. The misaligned values and beliefs inhibit relevant stakeholder engagement for transitions to a CE with responsibility shifted to civil society and public institutions. Management commitment to circularity transitions are at best a sophisticated form of circularity greenwashing. The study further suggests a general lack of collective disposition to foster collaborations with sectoral and supply chain partners to engender circularity transitions due to the absence of any standard systems for CE performance indicators. Circularity education and training play a positive mediatory role in changing negative assumptions, including the promotion of managers' engagement with other relevant stakeholders to build synergies and strategies for CE systems. The findings contribute to understanding the dynamics of corporate inertia regarding transitions to CE and highlight the relevance of aligning the personal values and beliefs of top management with organisational, sectoral, and supply chain partners’ values and goals.
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Stakeholder Engagement in Public Sector Sport Facility Projects : A case study on Stadionområdet in MalmöBravinger, John January 2024 (has links)
This study aims to examine Stakeholder Engagement in the construction of a new public sector sport facility and explore the stakeholder perspective on the engagement process. The construction of sports facilities is complex and requires stakeholder insights for a better end product. Stakeholders have expertise that the project management does not have, which can improve both the end product and the stakeholders' willingness to use the area. A case study has been conducted at the Stadionområdet in Malmö where an older sports facility is to be replaced with a new one. The study is based on Stakeholder Theory and Stakeholder Engagement and applies these theories to understand the tools used in the engagement process. A qualitative mixed methods approach has been used where both semi-structured interviews and document collection have been conducted. In total, eight semi-structured interviews were conducted with respondents from the project side, internal and external stakeholders. The study shows that the engagement processes used in Stadionområdet are mainly information meetings, workshops and working groups. Information meetings have been held in an initial stage to create understanding of the redevelopment, however, a further demand for these meetings has been identified. Workshops have been held with external stakeholders where stakeholders are given the opportunity to express their views on the design of the area. While workshops are seen as the most effective, they are considered to lack feedback, which creates irritation. Internally in Malmö Stad, working groups have been used. These work well, but the processes can sometimes be time-consuming as the decision-making paths are long and need to be confirmed by many. There are also problems with administrations not striving for the same end goal, which creates irritation and lack of understanding for each other's opinions. To overcome these challenges and streamline Stakeholder Engagement, Stadionområdet can introduce a contact person for the external stakeholders who creates communication channels and provides feedback after workshops. Marketing the final goal more clearly, for both internal and external stakeholders, is also of great importance so that stakeholders know what to expect.
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Transforming Trash to Treasure: Uncovering the Social Benefits of Industrial Symbiosis in ScandinaviaVitale, Valeria, Ziegler, Marie January 2024 (has links)
Background: The United Nation's Agenda 2030, which includes 17 Sustainable Development Goals (SDGs), emphasizes the importance of partnerships across different sectors to address global challenges. In particular, SDG 17 encourages multi-stakeholder collaborations to mobilize resources for sustainability. Despite their importance, there is limited research on the mechanisms of these partnerships, especially in terms of generating social value. Industrial Symbiosis (IS) is a prime example of such collaborations, focusing on resource exchange and shared services. However, the social aspects of IS have not been thoroughly explored, highlighting the need for further research to achieve comprehensive sustainability.Purpose: The purpose of this study is to contribute to the understanding of the contribution of Industrial Symbiosis initiatives in the Scandinavian Region on the existence of Social Benefits in the local community.Method: This study, grounded in the interpretivistic paradigm, follows a qualitative approach. Experts and practitioners within Industrial Symbiosis were interviewed and the data collected were analysed with an inductive-open coding process to then evolve in a thematic analysis.Conclusion: Our findings emphasize that Industrial Symbiosis is not merely an environmental strategy but a robust framework that actively contributes to local community development through job creation, industry retention, and infrastructure improvement, among others. By embracing a circular economy and engaging diverse stakeholders, IS demonstrates a sustainable model of industrial interaction that benefits both the environment and society. Overall, we conclude that the successful implementation of Industrial Symbiosis leads to substantial Social Benefits, reinforcing its role as a pivotal element in achieving Sustainable Development Goals.
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Hållbarhetsrapporteringen inom svensk dagligvaruhandel : hur engageras intressenter / Sustainability reporting within Swedish grocery retailers : how stakeholders are engagedKristensson, Lovisa, Carlsson, Cajsa January 2019 (has links)
Hållbarhet bygger på att företag tar ett socialt, miljömässigt och ekonomiskt ansvar. Med hjälp av hållbarhetsrapporten kommunicerar företag sitt hållbarhetsarbete och resultaten av det. Användarna av hållbarhetsrapporterna är företagets intressenter, vilka påverkar och påverkas av företagets verksamhet. För att företaget ska veta vilka frågor som intressenterna anser väsentliga behöver företaget engagera sina intressenter. Intressentengagemang är processen som används av företag för att engagera relevanta intressenter i hållbarhetsarbetet och för att välja ut vilka frågor som är väsentliga att ta med i hållbarhetsrapporten. Denna studie fokuserar på dagligvaruhandelsföretag och deras intressentengagemang. Syftet med denna studie är att undersöka hur dagligvaruhandelsföretag i Sverige engagerar sina intressenter i hållbarhetsrapporterna genom att utgå ifrån de tre principerna inkluderbarhet, väsentlighet och respons samt att jämföra hur engagemanget har förändrats under de senaste åren. För att uppfylla syftet har en kvantitativ ansats valts i form av innehållsanalys av hållbarhetsrapporter. Resultatet från studien visar att dagligvaruhandelsföretagen generellt är tydliga med vilka intressenter som inkluderas samt vilka frågor som anses väsentliga av intressenterna. De är dock inte lika transparenta med hur själva intressentengagemanget ser ut. Studien visar även att de metoder som främst används är one-way och two-way. / Sustainability is based on companies taking social, environmental and financial responsibility. With the help of a sustainability report, companies communicate their sustainability work and the results of it. The users of the sustainability reports are the company's stakeholders, which affect and are affected by the company's operations. In order for the company to know which issues stakeholders consider important, the company needs to engage its stakeholders. Stakeholder engagement is the process used by companies to engage relevant stakeholders in the sustainability work and to select which issues are essential to include in the sustainability report. This study focuses on grocery retailers and their stakeholder engagement. The purpose of this study is to investigate how grocery retailers in Sweden engage their stakeholders in the sustainability reports by using the three principles inclusivity, materiality and responsiveness and comparing how the engagement has changed during the recent years. To fulfil the purpose a quantitative approach has been chosen in the form of content analysis of sustainability reports. The results of the study show that the grocery retailers are generally clear about which stakeholders are included and which issues are considered essential by the stakeholders. However, they are not as transparent about how the stakeholder engagement itself looks. The study also shows that the methods that are mainly used are one-way and two-way.
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Internal governance, structures, board ethnicity, and external audit fees of Malaysian listed firmsYatim, Puan. Unknown Date (has links)
No description available.
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