L'IRM de perfusion et de spectroscopie restent encore peu utilisées en raison de leur mise en oeuvre difficile et de leur manque de quantification. L'objectif de ces travaux a été d'optimiser et de valider des techniques IRM totalement non invasives chez l'Homme en vue d'applications cliniques permettant une exploration sur un large volume cérébral et une quantification absolue des paramètres de perfusion et du métabolisme cérébraux. Concernant la perfusion, 3 séquences de type marquage de spins,PASL PICORE, PASL FAIR et pCASL, ont été comparées en termes de sensibilité et de reproductibilité. pCASL a ensuite été intégrée dans un protocole de recherche sur des patients atteints de sclérose en plaques ou SEP. Quant au métabolisme cérébral, un protocole a été mis en place afin d'accéder à une quantification absolue et pseudo absolue des métabolites par la normalisation du signal de l'eau issue de la CSI par la densité de protons acquise en IRM. Cette technique a été validée en CSI 2D puis transposée en 3D avec la séquence EPSI sur deux orientations différentes : CACP et CACP+15°afin de constituer des valeurs normatives fiables des métabolites principaux sur tout le cerveau. L'élaboration de ces techniques en spectroscopie a abouti à une étude sur des patients souffrant de SEP démontrant la faisabilité de l'utilisation de ces techniques en clinique. Ces travaux démontrent que la quantification absolue en IRM de perfusion et en IRM de spectroscopie peut être obtenue sur un large volume cérébral de manière fiable sur un système IRM disponible en environnement clinique dans un temps d'acquisition acceptable à travers les corrections diverses spécifiques à chaque imagerie. / Conventional MRI's lack of specificity in clinical routine limits our ability to perform correct diagnoses or follow-ups of pathological diseases. Two forms of NMR imaging, perfusion weighed and spectroscopic imaging provide information about two closely related characteristics :cerebral perfusion and metabolism. However, these techniques are not widely used due to the complexity of implementation and a lack of quantification.The general aim was to optimize and validate completely non-invasive NMR techniques for further human clinical applications in the context of exploring large cerebral volumes and determining absolute or pseudo-absolute quantification of cerebral perfusion and metabolism. Concerning perfusion, three arterial spin labeling sequences, PASL PICORE, PASL FAIR and pCASL, were compared in terms of sensitivity and reproducibility. The pCASL sequence was then integrated to a protocol applied to patients suffering from multiple sclerosis. In relation to metabolism, a protocol was applied in order to access absolute and pseudo-absolute metabolite quantification by water SI normalization from MRI proton density. This technique was validated on 2D CSI and then on 3D with EPSI sequence with two orientations, AC-PC and AC-PC+15 in order to generate reliable normative values of metabolites for the whole brain. The use of those spectroscopic techniques on patients suffering from multiple sclerosis allowed demonstrating the feasibility in clinic.This work demonstrates that reliable absolute quantification in perfusion weighted and spectroscopic imaging can be obtained with extensive coverage and with an acquisition time compatible with the reality of clinical exams.

Master's thesis deals with the financial analysis of the company Residence Belgická, s.r.o. and its task is to evaluate the financial situation of the company and determine its strengths and weaknesses. The work consists of two parts, the theoretical and the practical. The theoretical part describes and explains the methods used in the practical part. The practical part deals with the presentation and analysis of the company. Work includes analysis of absolute and differential indicators - horizontal and vertical analysis of balance sheet and profit and loss, ratio analysis, including profitability ratios, activity and liquidity analysis using credible and bankruptcy models and finally compares the company with the industry as well as direct competitors regarding to achieved hotel key indicators and indicators of financial analysis.

Ce manuscrit décrit comment les champs de vitesses solutions de l'équation de Navier-Stokes se comportent à grande échelle pour un forçage à petite échelle. Il analyse aussi le comportement à grande échelle des champs magnétiques solutions de l'équation d'induction cinématique lorsque le champs de vitesse est de petite échelle. Les résultats présentés ont été obtenus à l'aide de simulations numériques directes utilisant des algorithmes pseudo-spectraux des équations non modifiées ou avec un développement utilisant la méthode Floquet. Dans le cadre hydrodynamique, les simulations utilisant la méthode de Floquet permettent de retrouver les résultats de l'effet AKA à bas Reynolds et de les étendre pour des Reynolds d'ordre un. Elles permettent aussi d'étudier des écoulements AKA-stable et de mettre en évidence une autre instabilité pouvant être interprétée comme un effet de viscosité négative. Dans le cadre magnétique, l'effet alpha est observé sur une gamme de séparation d'échelle dépassant par plusieurs ordres de grandeur les autres résultats connus. Il est aussi montré que le taux de croissance de l'instabilité devient indépendant de la séparation d'échelle une fois que le champs magnétique est destabilisé dans ses petites échelles. Le spectre d'énergie et le temps du corrélation d'équilibre absolu solution de l'équation d'Euler tronquée sont présentés. Un nouveau régime où le temps de corrélation est régit par l’hélicité est mis en évidence. Ces résultats sont aussi comparés à ceux des modes de grande échelle de solutions de l'équation de Navier-Stokes forcée dans les petites échelles. Ils montrent que le temps de corrélation croit avec l'hélicité. / This manuscript describes how solutions of the Navier-Stokes equations behave in the large scales when forced in the small scales. It analyzes also the large scale behavior of magnetic fields solution of the kinetic induction equation when the velocity is in the small scales. The results were acquired with direct numeric simulation (DNS) using pseudo-spectral algorithms of the equations as well as their Floquet development. In the hydrodynamical case, the Floquet DNS were able to confirm the results of the AKA effect at low Reynolds number and extend them for Reynolds number of order one. The DNS were also used to study AKA-stable flows and identified a new instability that can be interpreted as a negative viscosity effect. In the magnetic case, the alpha effect is observe for a range of scale separation exceed know results by several orders of magnitude. It is also shown that the growth rate of the instability becomes independent of the scale separation once the magnetic field is destabilized in its small scales. The energy spectrum and the correlation time of absolute equilibrium solution of the truncated Euler equation are presented. A new regime where the correlation time is governed by helicity is exhibited. These results are also compared with those coming from large scale modes of solutions of the Navier-Stokes equation forced in the small scales. They show that the correlation time increases with the helicity of the flow.

The thesis ‘Evaluation of the financial situation in the firm and proposals to its improvement’ deals with the financial analysis and evaluates the financial situation of the company. The first part defines the theoretical foundations of processing the financial analysis, its tools, methods and ways of using. The subject of the second part is the application of selected methods of financial analysis and proposed recommendations how to solve problem areas, reduce the weaknesses and improve the financial situation of the company.

The aim of this diploma thesis is to salute the financial situation of company FC Vysočina Jihlava, a.s. in the years 2009 – 2013 with use of selected methods of the financial analysis, aplication of benchmarking method. In the final part of thesis are formulated suggestions and recommendations which should lead to result in the improvement problem areas

The aim of this work is description of a device developed at Brno University of Technology, Faculty of Civil Engineering, Institute of Geodesy for the purpose of absolute calibration of geodetic GNSS antennas. Thanks to calibration it is possible to remove systematic error of antenna's phase centre. The device consists of moveable arm and processing unit. The moveable arm is able to set up calibrated antenna to required azimuth and elevation angle. This work introduces the issue of absolute calibration, describes the moveable arm and the process of its assembling. Further, it defines geometrical parameters of moveable arm, describes their determination and their independent verification by geodetic method. Finally, the model of movement of antenna's reference point is described.

La compétence du laboratoire dans le domaine du transport électronique a été étendue par un travail métrologique permettant de préciser l’échelle de thermoélectricité notamment en corrigeant l’alumel. Dans une deuxième partie nous avons utilisé l’excellente précision du dispositif expérimental pour mesurer le Pouvoir Thermoélectrique Absolu (PTA) d’échantillons d’Arcelor auparavant caractérisés à haute température par résistivité. Puis nous avons déterminé, pour la première fois, les propriétés de transport électronique de 4 pseudo-alliages en fonction de la température et avons étudié l’effet de leur vieillissement à haute température / The competence of the laboratory in the field of electronic transport has been extended by a metrological work to specify the scale of thermoelectricity correcting that of alumel. In a second part, we used the excellent precision of the experimental device to measure the Absolute Thermoelectric Power (ATP) of Arcelor samples previously characterized at high temperature by resistivity. Then we determined, for the first time, the electronic transport properties of four pseudo-alloys as function of temperature and studied the effect of their ageing at high temperatures

Automatic text summarization and keyphrase extraction are two interesting areas of research which extend along natural language processing and information retrieval. They have recently become very popular because of their wide applicability. Devising generic techniques for these tasks is challenging due to several issues. Yet we have a good number of intelligent systems performing the tasks. As different systems are designed with different perspectives, evaluating their performances with a generic strategy is crucial. It has also become immensely important to evaluate the performances with minimal human effort. In our work, we focus on designing a relativized scale for evaluating different algorithms. This is our major contribution which challenges the traditional approach of working with an absolute scale. We consider the impact of some of the environment variables (length of the document, references, and system-generated outputs) on the performance. Instead of defining some rigid lengths, we show how to adjust to their variations. We prove a mathematically sound baseline that should work for all kinds of documents. We emphasize automatically determining the syntactic well-formedness of the structures (sentences). We also propose defining an equivalence class for each unit (e.g. word) instead of the exact string matching strategy. We show an evaluation approach that considers the weighted relatedness of multiple references to adjust to the degree of disagreements between the gold standards. We publish the proposed approach as a free tool so that other systems can use it. We have also accumulated a dataset (scientific articles) with a reference summary and keyphrases for each document. Our approach is applicable not only for evaluating single-document based tasks but also for evaluating multiple-document based tasks. We have tested our evaluation method for three intrinsic tasks (taken from DUC 2004 conference), and in all three cases, it correlates positively with ROUGE. Based on our experiments for DUC 2004 Question-Answering task, it correlates with the human decision (extrinsic task) with 36.008% of accuracy. In general, we can state that the proposed relativized scale performs as well as the popular technique (ROUGE) with flexibility for the length of the output. As part of the evaluation we have also devised a new graph-based algorithm focusing on sentiment analysis. The proposed model can extract units (e.g. words or sentences) from the original text belonging either to the positive sentiment-pole or to the negative sentiment-pole. It embeds both (positive and negative) types of sentiment-flow into a single text-graph. The text-graph is composed with words or phrases as nodes, and their relations as edges. By recursively calling two mutually exclusive relations the model builds the final rank of the nodes. Based on the final rank, it splits two segments from the article: one with highly positive sentiment and the other with highly negative sentiments. The output of this model was tested with the non-polar TextRank generated output to quantify how much of the polar summaries actually covers the fact along with sentiment.

This thesis aims to investigate the eect context could have to interaction between a user and a spoken dialogue system. It was assumed that using context-dependent voice commands instead of absolute semantic voice commands would make the dialogue more natural and also increase the usability. This thesis also investigate if introducing context could aect the user's privacy and if it could expose a threat for the user from a user perspective. Based on an extended literature review of spoken dialogue system, voice recognition, ambient intelligence, human-computer interaction and privacy, a spoken dialogue system was designed and implemented to test the assumption. The test study included two steps: experiment and interview. The participants conducted the dierent scenarios where a spoken dialogue system could be used with both context-dependent commands and absolute semantic commands. Based on these studies, qualitative results regarding natural, usability and privacy validated the authors hypothesis to some extent. The results indicated that the interaction between users and spoken dialogue systems was more natural and increased the usability when using context. The participants did not feel more monitored by the spoken dialogue system when using context. Some participants stated that there could be a theoretical privacy issues, but only if the security measurements were not met. The paper concludes with suggestions for future work in the scientic area. / Denna uppsats har som mal att undersoka vilken eekt kontext kan ha pa interaktion mellan en anvandare och ett spoken dialogue system. Det antogs att anvandbarheten skulle oka genom att anvanda kontextberoende rostkommandon istallet for absolut semantiska rostkommandon. Denna uppsats granskar aven om kontext kan paverka anvandarens integritet och om den, ur ett anvandarperspektiv, kan utgora ett hot. Baserat pa den utokade litteraturstudien av spoken dialogue system, rostigenkanning, ambient intelligence, manniska-datorinteraktion och integritet, designades och implementerades ett spoken dialogue system for att testa detta antagande. Teststudien bestod av tva steg: experiment och intervju. Deltagarna utforde olika scenarier dar ett spoken dialogue system kunde anvands med kontextberoende rostkommandon och absolut semantiska rostkommandon. Kvalitativa resultat angaende naturlighet, anvandbarhet och integritet validerade forfattarens hypotes till en viss grad. Resultatet indikerade att interaktionen mellan anvandare och ett spoken dialogue system var mer naturlig och mer anvandbar vid anvandning av kontextberoende rostkommandon istallet for absolut semantiska rostkommandon. Deltagarna kande sig inte mer overvakade av ett spoken dialogue system vid anvandning av kontextberoende rostkommandon. Somliga deltagare angav att det, i teorin, fanns integritetsproblem, men endast om inte alla sakerhetsatgarder var uppnadda. Uppsatsen avslutas med forslag pa framtida studier inom detta vetenskapliga omrade.

Previous studies highlighted the importance of parental support for development of mastery of control and depressive symptoms. These studies tended to examine one time wave and outcomes related to that period, forwarding an assumption parenting behaviours do not change as children age. Using the National Longitudinal Survey of Youth 1979-Children and Young Adults, this study filled the gap by examining children's supportive environment at three time points and determining how levels of support across these points impacted children's depression and mastery at 18 years of age. Relative stability of mothers' supportive parenting (i.e., encouragement of social maturity, warmth and affection, and physical punishment) at early childhood, middle childhood, and early adolescence was examined by Kendall's tau correlations. Encouragement of social maturity showed relative stability between early and middle childhood and middle childhood and early adolescence; warmth and affection showed relative stability between early and middle childhood, and physical punishment showed relative stability across all time points. Absolute stability was examined using hierarchical linear modelling and Wilcoxon signed-rank test. No instances were found. Latent class growth analysis identified different trajectories of supportive environment among participants and three groups were identified. Multiple regressions conducted to examine how different trajectories affect late adolescents' depression and mastery found children of mothers from the least supportive group had statistically significant higher level of depression and lower level of mastery of control at 18 years of age; children of mothers from the progressively and continuously supportive group had similarly positive results of depression and mastery.