L’expérience JEM-EUSO (traduction de Observatoire spatial de l’univers extrême à bord du module de l'expérience japonaise) est conçu pour observer les UHECR en détectant la lumière fluorescente UV émise par la gerbe qui se développe lorsque les UHECR interagissent avec l'atmosphère terrestre. Les gerbes atmosphériques sont constituées de dizaines de milliards de particules secondaires ou plus traversant l'atmosphère quasiment à la vitesse de la lumière, excitant les molécules d'azote qui émettent ensuite de la lumière dans la gamme UV. Alors que cette « technique de fluorescence » est habituellement utilisée au sol, en opérant ainsi à partir de l'espace, JEM-EUSO, pour la première fois, fournira des statistiques élevées sur ces événements. Avec un large champ de vue de ± 30 °, JEM-EUSO pourra observer depuis l’espace un volume d'atmosphère beaucoup plus grand que ce qui est possible du sol, en collectant un nombre sans précédent d'événements UHECR aux plus hautes énergies.Pour les quatre prototypes d’expériences construites par la collaboration, nous avons développé un ensemble commun d'électronique, en particulier le système central d'acquisition de données capable de fonctionner au sol, sur des ballons à haute altitude et dans l'espace.Ces expériences utilisent toutes un détecteur composé d'un module de détection de photo (PDM) identique aux 137 qui seront présents sur la surface focale JEM-EUSO. La lumière UV générée par les gerbes atmosphériques à haute énergie passe le filtre UV et frappe les tubes à photomultiplicateurs multi-anodes (MAPMT). Les photons UV sont alors transformés en électrons, qui sont multipliés par les MAPMT et le courant qu’ils créent est amplifié par des cartes ASIC de circuit intégré (EC-ASIC), qui effectuent également le comptage des photons et l'estimation de charge. Une carte FPGA nommé PDM board s'interface avec ces cartes ASIC, fournissant des paramètres d'alimentation et de configuration à ces cartes ASIC, collecte alors les données et exécute le déclenchement d’acquisition de niveau 1.Dans le cadre de ces travaux, je me suis occupée de la conception, du développement, de l'intégration et du test la carte FPGA PDM board pour les missions EUSO-TA et EUSO-Balloon ainsi que des tests d'algorithme de déclenchement autonomes d’acquisitions et j'ai également analysé les données de vol d’EUSO-Balloon et de la campagne sol EUSO-TA d’octobre 2015.Dans cette thèse, je donnerai un bref aperçu des rayons cosmiques à haute énergie, y compris de leur technique de détection et des principales expériences pour les détecter (chapitre 1), je décrirai JEM-EUSO et ses pathfinders (chapitre 2), je présenterai les détails de la conception et de la fabrication du PDM (chapitre 3) et de la carte FPGA PDM board (chapitre 4), ainsi que des tests d'intégration d’EUSO-TA et d’EUSO-Balloon (chapitre 5). Je ferai un rapport sur la campagne EUSO-Balloon de 2014 (chapitre 6) et sur ses résultats (chapitre 7), y compris une analyse spécifique développée pour rechercher des variations globales de l'émissivité UV au sol et j’appliquerai une analyse similaire aux données collectées sur le site de Telescope Array (Chapitre 8). Enfin, je présenterai la mise en œuvre et le test du déclencheur de premier niveau (L1) dans la carte de contrôle FPGA (chapitre 9). Un bref résumé de la thèse sera donné au chapitre 10. / The JEM-EUSO (Extreme Universe Space Observatory on-board the Japanese Experiment Module) international space mission is designed to observe UHECRs by detecting the UV fluorescence light emitted by the so-called Extensive Air Shower (EAS) which develop when UHECRs interact with the Earth’s atmosphere. The showers consist of tens of billions or more secondary particles crossing the atmosphere at nearly the speed of light, which excite nitrogen molecules which then emit light in the UV range. While this so-called “fluorescence technique'” is routinely used from the ground, by operating from space, JEM-EUSO will, for the first time, provide high-statistics on these events. Operating from space, with a large Field-of-View of ±30 °, allows JEM-EUSO to observe a much larger volume of atmosphere, than possible from the ground, collecting an unprecedented number of UHECR events at the highest energies.For the four pathfinder experiments built within the collaboration, we have been developing a common set of electronics, in particular the central data acquisition system, capable of operating from the ground, high altitude balloons, and space.These pathfinder experiments all use a detector consisting of one Photo-detection Modules (PDMs) identical to the 137 that will be present on the JEM-EUSO focal surface. UV light generated by high-energy particle air showers passes the UV filter and impacts the Multi-anode Photomultiplier Tubes (MAPMT). Here UV photons are converted into electrons, which are multiplied by the MAPMTs and fed into Elementary Cell Application-Specific Integrated Circuit (EC-ASIC) boards, which perform the photon counting and charge estimation. The PDM control board interfaces with these ASIC boards, providing power and configuration parameters, collecting data and performing the level 1 trigger. I was in charge of designing, developing, integrating, and testing the PDM control board for the EUSO-TA and EUSO-Balloon missions as well as the autonomous trigger algorithm testing and I also performed some analysis of the EUSO-Balloon flight data and data from the EUSO-TA October 2015 run.In this thesis, I will give a short overview of high-energy cosmic rays, including their detection technique and the leading experiments (Chapter 1), describe JEM-EUSO and its pathfinders including a description of each instrument (Chapter 2), present the details of the design and the fabrication of the PDM (Chapter 3) and PDM control board (Chapter 4), as well as the EUSO-TA and EUSO-Balloon integration tests (Chapter 5). I will report on the EUSO-Balloon campaign (Chapter 6) and results (Chapter 7), including a specific analysis developed to search for global variations of the ground UV emissivity, and apply a similar analysis to data collected at the site of Telescope Array (Chapter 8). Finally, I will present the implementation and testing of the first-level trigger (L1) within the FPGA of the PDM control board (Chapter 9). A short summary of the thesis will be given in Chapter 10.

No description available.

International Telemetering Conference Proceedings / October 18-21, 2004 / Town & Country Resort, San Diego, California / This paper describes a high altitude experimental flight test platform developed by the University of Kansas (KU) and the National Nuclear Security Administration’s Kansas City Plant (NNSA’s Kansas City Plant) for high altitude payload flight testing. This platform is called the Kansas University Balloon Experiment Satellite (KUBESat). The paper describes the flight test platform and experimental flight test results captured at Fort Riley, KS from characterization of the KCP developed Distributed Transmitter (DTX).

Neste trabalho, buscou-se avaliar se o uso do balão intragástrico (BI) durante um período de seis meses por pacientes obesos ou com sobrepeso e com síndrome metabólica (SM) traz melhora nos parâmetros de função pulmonar, distribuição da gordura corporal e SM. Trata-se de um estudo longitudinal e intervencionista com indivíduos adultos que foram submetidos à avaliação antropométrica, da bioquímica sérica, dos parâmetros de função pulmonar e do padrão de distribuição da gordura corporal, antes da instalação do BI, durante o acompanhamento de seis meses e após a sua retirada. Nos dados obtidos três meses após a colocação do BI, os pacientes apresentaram aumento da capacidade de difusão ao monóxido de carbono com correlação positiva entre esta e o percentual total de gordura corporal (rs=0,39; p=0,05), o padrão ginoide (rs=0,41; p=0,05) e o padrão torácico (rs=0,42; p=0,01). Também foi observado que, após três meses da colocação do BI, houve redução significativa do índice de massa corpórea (IMC) (p=0,0001) e da força muscular inspiratória (p=0,009). Também houve aumento significativo da capacidade vital forçada (CVF) (p=0,0001), da capacidade pulmonar total (CPT) (p=0,001) e do volume de reserva expiratório (VRE) (p=0,0001). Ao fim do estudo, foi observada elevação estatisticamente significante da CPT (p=0,0001), capacidade residual funcional (p=0,0001), volume residual (VR) (p=0,0005) e VRE (p=0,0001). Também foi observada redução significativa do IMC, cuja mediana passou de 39,1 kg/m2 no início da avaliação para 34,5 kg/m2 no final dos seis meses (p=0,0001). Ao fim do estudo, 31 pacientes (77,5%) não apresentavam mais critérios diagnósticos para SM. Em relação aos parâmetros de distribuição da gordura corporal, também houve mudanças importantes com redução significante (p=0,0001) do percentual de gordura nos quatro padrões analisados (tronco, androide, ginoide e total). Houve correlação significante entre o delta da CPT e o delta da circunferência abdominal (ρ=-0,34; p=0,03), entre o delta da CRF e o delta do IMC (ρ=-0,39; p=0,01) e entre o delta do VRE e os deltas do IMC (ρ=-0,44; p=0,005) e do colesterol HDL (ρ=-0,37; p=0,02). Também houve correlação significante entre o delta do VRE com os deltas das gorduras de tronco (ρ=-0,51; p=0,004), androide (ρ=-0,46; p=0,01), ginoide (ρ=-0,55; p=0,001) e total (ρ=-0,59; p=0,0005). / This work aimed to evaluate if the use of intragastric balloon (IB) for a period of six months in obese patients or overweight and metabolic syndrome (MS) brings improvement in the parameters of pulmonary function, body fat distribution and MS. This is a longitudinal and interventional study with adults who underwent anthropometric measurements, serum biochemistry, pulmonary function parameters and the pattern of distribution of body fat before the IB installation, during follow-up of six months and after their withdrawal. In data obtained three months after the placing of BI we observed a statistically significant positive correlation between the capacity of diffusion and the percentage of whole-body fat mass (rs=0.39; p=0.05), gynoid fat mass (rs=0.41; p=0.05), and trunk fat mass (rs=0.42; p=0.01). It was also noted that, after three months of placement of BI, there was a significant reduction in the body mass index (BMI) (p=0.0001) and the maximal inspiratory pressure (p=0.009). We also observed a significant increase in the forced vital capacity (FVC) (p=0.0001), total lung capacity (TLC) (p=0.001), and expiratory reserve volume (ERV) (p=0.0001). At the end of the study it was observed that the TLC (p=0.0001), functional residual capacity (FRC) (p=0.0001), residual volume (p=0.0005), and ERV (p=0.0001) were significantly increased by IB. The BMI significantly decreased from a median of 39.1 kg/m2 at the beginning of the study to 34.5 kg/m2 at the end of the six-month period (p=0.0001). At this time, 31 participants (77.5%) no longer met the diagnostic criteria of MS. The parameters of body fat distribution also exhibited remarkable changes. The percentage of fat in all four investigated patterns of distribution (truncal, android, gynoid, and total) exhibited significant reductions (p=0.0001). Significant correlations were found between delta TLC and delta abdominal circumference (ρ=-0.34; p=0.03), delta FRC and delta BMI (ρ=-0.39; p=0.01), delta ERV and delta BMI (ρ=-0.44; p=0.005), and delta ERV and delta high-density lipoprotein (HDL) (ρ=-0.37; p=0.02). Significant correlations were also found between delta ERV and delta truncal (ρ=-0.51; p=0.004), android (ρ=-0.46; p=0.01), gynoid (ρ=-0.55; p=0.001), and total fat (ρ=-0.59; p=0.0005).

Extenderes: vídeo-ações são ações registradas e apresentadas em vídeo, nas quais meu corpo estabelece relações com vestíveis e com balões no espaço de um quarto. Essas vídeo-ações foram desenvolvidas entre os anos de 2011 e 2013. Assim criei situações que levavam meu corpo a explorar outras formas de movimentação e percepção do espaço a minha volta. Ao longo desta dissertação são esmiuçados alguns conceitos que se referem à relação do meu corpo com o objeto no momento da ação, são eles o conceito de jogo tratado por Hans-Georg Gadamer, o conceito de secundidade desenvolvido por Charles Peirce e o conceito de tarefa introduzido na dança por Ana Halprin. Também são pensadas algumas questões presentes nessas ações do grupo Extenderes como a repetição, a vulnerabilidade do corpo e a exaustão. O processo de criação é abordado segundo a função do fantasma na psicanálise, e também, segundo a experimentação, e a ludicidade como forma de construção. / Extenderes: video-actions are actions recorded on video, in which my body establishes relationships with wearable pieces and balloons in the space of a room. This video-actions were developed between 2011 and 2013. So I created situations that led my body to explore others forms of movement and perception of the space around me. Throughout this dissertation are scrutinized some concepts that refer to the relationship of my body with the object at the time of action. They are the play concept by Hans Georg Gadamer, the concept of secondness developed by Charles Peirce and the concept of the task introduced in dance by Ana Halprin. Also are thought some questions present in those actions Extenderes group as repetition, body vulnerability and exhaustion. The creation process is discussed according to the function of the fantasy in psychoanalysis, and also according playfulness as a way of building.

為有效了解地表資訊，可視研究目的而利用各種遙測方法獲取地面影像，但不論目前常用之飛機、或是以衛星為載具之空中攝影測量等相關研究，在影像獲取方面，常面臨成本費用、機動性、比例尺需求、後續影像處理等問題。因此，本研究選定一小流域面積之河川作為實驗區，並設計以氣球為載具之數值航空攝影方式，裝載CCD攝影機以及數位攝影機，透過CCD攝影機，即時無線傳輸地面影像至監視螢幕，調整氣球至預定之位置後，遙控啟動數位攝影機之快門裝置。 　　研究設計之攝影方式曾實際應用於偵測河道之變遷，由成果影像中檢核點之精度結果，以及套疊正射糾正並鑲嵌後之河道影像與地形圖之成果，證明氣球載具之數值航空攝影方式，確能有效應用於大比例尺製圖之研究。 / Using a flexible and efficient way to obtain aerial images has been the primary purpose of this study. The balloon platform was used to take aerial images. A video camera and a digital camera were fixed together in a durable plastic box, and hung on the balloon. The video camera was used to monitor the ground view, and its image could be telemetered remotely and displayed on a LCD monitor arranged on the ground. Once monitoring the area of interest shown on the LCD, the shutter button of the digital camera was then pushed remotely and the interested image was taken. 　　The resultant images were ortho-rectified for analysis and comparison. The accuracy of aerial images was examined by check points. The results showed that the images achieved sub-pixel accuracy and were well-matched with the 1/1000 digital topographic maps. This expressed that it was really a useful and efficient method of taking large-scale images for a small research area. 　　At last, post-classification comparison method was introduced to detect change of the ortho-rectified images which were taken in three different periods. The classification maps and the from-to change class information clearly indicated the change of river way among various periods.

L’étude des aérosols stratosphériques est importante pour comprendre le bilan radiatif terrestre. A l’heure actuelle, notre représentation des différents types de particules stratosphériques et leurs répartitions spatiale et temporelle n’est pas complète. Au cours de cette thèse, nous tentons de montrer que la mesure de la concentration en particules sous ballon météorologique au moyen d’un nouveau mini compteur de particules, le LOAC, pourrait permettre de rendre compte de la possible variabilité locale du contenu en aérosols stratosphériques dans la gamme de taille 0,2 à 100 μm en diamètre. La première partie de ce travail consiste à caractériser plus précisément les performances du LOAC sous ballon météorologique appliqué à la mesure en stratosphère. La seconde partie propose une analyse comparée du contenu en aérosols stratosphériques obtenu par LOAC, à partir de lâchers de ballons en France régulièrement depuis 3 ans et plus ponctuellement à l’étranger dans des situations particulières (volcan, mousson), et par d’autres types de données (Observations spatiales, lidar sol et simulation globale). Nous montrons alors que l’instrument possède une limite de détection rendant difficile la mesure des particules submicroniques lors de période de fond en moyenne stratosphère pour des concentrations de l’ordre d’une particule par cm3. Dans sa version actuelle, le LOAC permet de documenter les panaches volcaniques en troposphère ainsi qu’en basse stratosphère. En perspective, nous proposons des directions pour la calibration et l’analyse des futures données d’une nouvelle génération de l’instrument en développement. / The study of the stratospheric aerosols is important to our understanding of the terrestrial radiative budget. Our current comprehension of the different types of stratospheric particles and their spatial and temporal distribution is incomplete. In the present study, we try to show that measuring particle concentrations by the means of a new balloon-borne miniature particle counter, the LOAC, may allow us to determine the local variability in stratospheric aerosols in the size range 0.2 – 100 μm in diameter. In that respect, the PhD thesis consists of a first phase of a more accurate characterisation of the LOAC’s performances under balloon-borne measurement. A second phase consists of comparative analysis of stratospheric aerosol content based on a LOAC dataset obtained during a continuous campaign of balloon launches in France, along with some occasional flights abroad under particular circumstances (volcanic eruption, monsoon). Thus we show that the LOAC has a detection limit that restricts the measurement of submicronic particles in volcanic quiescent periods for concentrations lower than typically 1 particle per cm3. In its current version, the LOAC allows us to characterise aerosols in volcanic plumes in the troposphere and lower stratosphere. And, further, we propose directions concerning possible calibration and analysis strategies for the future data from the next generation of the LOAC currently in development.

Neste trabalho, buscou-se avaliar se o uso do balão intragástrico (BI) durante um período de seis meses por pacientes obesos ou com sobrepeso e com síndrome metabólica (SM) traz melhora nos parâmetros de função pulmonar, distribuição da gordura corporal e SM. Trata-se de um estudo longitudinal e intervencionista com indivíduos adultos que foram submetidos à avaliação antropométrica, da bioquímica sérica, dos parâmetros de função pulmonar e do padrão de distribuição da gordura corporal, antes da instalação do BI, durante o acompanhamento de seis meses e após a sua retirada. Nos dados obtidos três meses após a colocação do BI, os pacientes apresentaram aumento da capacidade de difusão ao monóxido de carbono com correlação positiva entre esta e o percentual total de gordura corporal (rs=0,39; p=0,05), o padrão ginoide (rs=0,41; p=0,05) e o padrão torácico (rs=0,42; p=0,01). Também foi observado que, após três meses da colocação do BI, houve redução significativa do índice de massa corpórea (IMC) (p=0,0001) e da força muscular inspiratória (p=0,009). Também houve aumento significativo da capacidade vital forçada (CVF) (p=0,0001), da capacidade pulmonar total (CPT) (p=0,001) e do volume de reserva expiratório (VRE) (p=0,0001). Ao fim do estudo, foi observada elevação estatisticamente significante da CPT (p=0,0001), capacidade residual funcional (p=0,0001), volume residual (VR) (p=0,0005) e VRE (p=0,0001). Também foi observada redução significativa do IMC, cuja mediana passou de 39,1 kg/m2 no início da avaliação para 34,5 kg/m2 no final dos seis meses (p=0,0001). Ao fim do estudo, 31 pacientes (77,5%) não apresentavam mais critérios diagnósticos para SM. Em relação aos parâmetros de distribuição da gordura corporal, também houve mudanças importantes com redução significante (p=0,0001) do percentual de gordura nos quatro padrões analisados (tronco, androide, ginoide e total). Houve correlação significante entre o delta da CPT e o delta da circunferência abdominal (ρ=-0,34; p=0,03), entre o delta da CRF e o delta do IMC (ρ=-0,39; p=0,01) e entre o delta do VRE e os deltas do IMC (ρ=-0,44; p=0,005) e do colesterol HDL (ρ=-0,37; p=0,02). Também houve correlação significante entre o delta do VRE com os deltas das gorduras de tronco (ρ=-0,51; p=0,004), androide (ρ=-0,46; p=0,01), ginoide (ρ=-0,55; p=0,001) e total (ρ=-0,59; p=0,0005). / This work aimed to evaluate if the use of intragastric balloon (IB) for a period of six months in obese patients or overweight and metabolic syndrome (MS) brings improvement in the parameters of pulmonary function, body fat distribution and MS. This is a longitudinal and interventional study with adults who underwent anthropometric measurements, serum biochemistry, pulmonary function parameters and the pattern of distribution of body fat before the IB installation, during follow-up of six months and after their withdrawal. In data obtained three months after the placing of BI we observed a statistically significant positive correlation between the capacity of diffusion and the percentage of whole-body fat mass (rs=0.39; p=0.05), gynoid fat mass (rs=0.41; p=0.05), and trunk fat mass (rs=0.42; p=0.01). It was also noted that, after three months of placement of BI, there was a significant reduction in the body mass index (BMI) (p=0.0001) and the maximal inspiratory pressure (p=0.009). We also observed a significant increase in the forced vital capacity (FVC) (p=0.0001), total lung capacity (TLC) (p=0.001), and expiratory reserve volume (ERV) (p=0.0001). At the end of the study it was observed that the TLC (p=0.0001), functional residual capacity (FRC) (p=0.0001), residual volume (p=0.0005), and ERV (p=0.0001) were significantly increased by IB. The BMI significantly decreased from a median of 39.1 kg/m2 at the beginning of the study to 34.5 kg/m2 at the end of the six-month period (p=0.0001). At this time, 31 participants (77.5%) no longer met the diagnostic criteria of MS. The parameters of body fat distribution also exhibited remarkable changes. The percentage of fat in all four investigated patterns of distribution (truncal, android, gynoid, and total) exhibited significant reductions (p=0.0001). Significant correlations were found between delta TLC and delta abdominal circumference (ρ=-0.34; p=0.03), delta FRC and delta BMI (ρ=-0.39; p=0.01), delta ERV and delta BMI (ρ=-0.44; p=0.005), and delta ERV and delta high-density lipoprotein (HDL) (ρ=-0.37; p=0.02). Significant correlations were also found between delta ERV and delta truncal (ρ=-0.51; p=0.004), android (ρ=-0.46; p=0.01), gynoid (ρ=-0.55; p=0.001), and total fat (ρ=-0.59; p=0.0005).

Extenderes: vídeo-ações são ações registradas e apresentadas em vídeo, nas quais meu corpo estabelece relações com vestíveis e com balões no espaço de um quarto. Essas vídeo-ações foram desenvolvidas entre os anos de 2011 e 2013. Assim criei situações que levavam meu corpo a explorar outras formas de movimentação e percepção do espaço a minha volta. Ao longo desta dissertação são esmiuçados alguns conceitos que se referem à relação do meu corpo com o objeto no momento da ação, são eles o conceito de jogo tratado por Hans-Georg Gadamer, o conceito de secundidade desenvolvido por Charles Peirce e o conceito de tarefa introduzido na dança por Ana Halprin. Também são pensadas algumas questões presentes nessas ações do grupo Extenderes como a repetição, a vulnerabilidade do corpo e a exaustão. O processo de criação é abordado segundo a função do fantasma na psicanálise, e também, segundo a experimentação, e a ludicidade como forma de construção. / Extenderes: video-actions are actions recorded on video, in which my body establishes relationships with wearable pieces and balloons in the space of a room. This video-actions were developed between 2011 and 2013. So I created situations that led my body to explore others forms of movement and perception of the space around me. Throughout this dissertation are scrutinized some concepts that refer to the relationship of my body with the object at the time of action. They are the play concept by Hans Georg Gadamer, the concept of secondness developed by Charles Peirce and the concept of the task introduced in dance by Ana Halprin. Also are thought some questions present in those actions Extenderes group as repetition, body vulnerability and exhaustion. The creation process is discussed according to the function of the fantasy in psychoanalysis, and also according playfulness as a way of building.

Introducción: La intervención coronaria percutánea primaria durante las 24 primeras horas de inicio del dolor torácico reduce la mortalidad por infarto de miocardio con ST elevado (IMA STE). El objetivo del estudio fue evaluar la mortalidad intrahospitalaria a 30 días según el tiempo puerta-balón y el tiempo total de isquemia en pacientes con IAM STE sometidos a intervención coronaria percutánea (ICP) primaria en un hospital de referencia. Métodos: Estudio retrospectivo de cohorte de pacientes con IMA STE sometidos a ICP primaria en un hospital de referencia de Lima, Perú. Analizamos la asociación entre el tiempo total de isquemia menor a 12 horas y tiempo puerta balón menor a 90 minutos con mortalidad a 30 días, mediante Regresión de Cox, ajustado por otros factores. Resultados: Durante el periodo 2010-2014, 296 sujetos con IMA STE fueron sometidos a ICP primaria. El 82,4% fueron varones y la media de edad fue 66,5 años ±11,8. La mortalidad intrahospitalaria a 30 días fue 8,11%. El 82,43% tuvo un tiempo total de isquemia menor a 12 horas y el 33,11% un tiempo puerta-balón menor a 90 minutos. No se encontró asociación entre ambos tiempos y mortalidad intrahospitalaria. El paro cardiaco (HR: 2,9 IC 95% 1,09-7,72), shock cardiogénico al ingreso (HR: 7,06 IC 95% 2,84-17,59) y un flujo TIMI menor a 3 post ICP (HR: 4,21 IC 95% 1,73-10,19) se asociaban a mayor mortalidad. Conclusión: No hubo asociación entre los tiempos estudiados con la mortalidad intrahospitalaria. Se sugieren intervenciones para disminuir los tiempos en esta población. / Introduction: Primary percutaneous coronary intervention reduces mortality in patients with ST elevated myocardial infarction (STE MI). The objective was to evaluate the 30 days in-hospital mortality according to door-to-balloon time and total ischemic time in patients treated with primary PCI. Methods: A retrospective cohort study was performed including patients with STE MI who underwent primary PCI at a national reference hospital in Lima, Peru. A Cox Regression analysis was performed for door-to-balloon time less than 90 minutes and total ischemic time less than 12 hours as predictors and in-hospital mortality as outcome. Results: During 2010’2014, 296 STE MI patients underewent PCI. From them, 82,4% were male. The mean age was 66,5 ±11,8 years. The 30-day mortality was 8,11%. The proportion of patients with total ischemic time less than 12 hours and door-to-balloon time was 82,43% and 33,11% respectively. No association between these intervals and 30-day mortality was found. Cardiac arrest (HR: 2,9 95%CI 1,09-7,72), cardiogenic shock at the admission (HR: 7,06; 95%CI: 2,84- 17,59) and TIMI flow less than 3 after primary PCI (HR: 4,21; 95%CI: 1,73-10,19) were associated with higher 30-day mortality.. Conclusion: No association between mortality and lower total ischemia time or door to ballon time mortality was found. A significant delay was observed in hospital arrival and performing revascularization.