In the vast majority of cases, appropriate identification and mitigation of risk factors can prevent or minimize pressure ulcer (PU) formation. However, some PUs are unavoidable. Based on the importance of this topic and the lack of literature focused on PU unavoidability, the National Pressure Ulcer Advisory Panel hosted a multidisciplinary conference in 2014 to explore the issue of PU unavoidability within an organ system framework, which considered the complexities of nonmodifiable intrinsic and extrinsic risk factors. Prior to the conference, an extensive literature review was conducted to analyze and summarize the state of the science in the area of unavoidable PU development and items were developed. An interactive process was used to gain consensus based on these items among stakeholders of various organizations and audience members. Consensus was reached when 80% agreement was obtained. The group reached consensus that unavoidable PUs do occur. Consensus was also obtained in areas related to cardiopulmonary status, hemodynamic stability, impact of head-of-bed elevation, septic shock, body edema, burns, immobility, medical devices, spinal cord injury, terminal illness, and nutrition.

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This dissertation examines the robust regression methods. The primary purpose of this work is to propose an extension, derivation and summary (including computational algorithm) for Theil-Sen's regression estimates (or in some literature also referred to as Passing-Bablok's regression method) for multi-dimensional space and compare this method to other robust regression methods. The combination of these two objectives is the primary and the original contribution of the dissertation. Based on the available literature it is unknown if anyone has discussed this problem in greater depth and solved it in total. Therefore this work provides a summary overview of the issue and offers a new alternative of this multidimensional, nonparametric, robust regression method. Secondary goals include a clear summary of other robust methods, a summary of findings related to these robust regression methods, robust methods compared with each other placing emphasis on the comparison with the proposed Theil-Sen's regression estimates method and with the least squares method. The summary also includes individual mathematical context and interchangeability of the proposed methods. These secondary objectives are also another benefit of this dissertation in the field of robust regression problems; this is especially important to gain a unified view of the problems of robust regression methods and estimates in general.

This thesis presents a research effort aimed at developing using construction methods and techniques in army tactical shelter. The beginning step focuses on developing and identifying different activities and work breakdown structure applicable in shelter prototype. The next step focuses on identifying resource allocation. This include allocate resources based on the delivered project as per alternative one and for the second alternative as optimization, resource allocation modified and tried to level and minimize resource peak. In addition, the cost calculated for the whole project as well as for each WBS and activities which consider as alternative one and in the second alternative, cost mitigation applied according to available resources and adjusting predecessors and successors of each activity. In conclusion, two alternatives compared, available outcome presents, and future work suggested for the project team to continue this effort.

Cancrinite specimens from Ontario were studied. Chemical and thermogravimetric analyses were made. Non-Bragg reflections were observed in x-ray photographs. These reflections have the same symmetry as the main lattice reflections, but the intensities, abundance and the relative positions of them with respect to the main lattice reflections are different from one specimen to another. In the heated specimens, the superstructure reflections decrease in intensities, shift in position and are streaked in a direction parallel to the a*-axis on the a* c* reciprocal lattice plane. Phase changes in the heated cancrinites show that the sodalite group of minerals occur as transitional phases in the cancrinite break down reactions. It is shown that the non-Bragg reflections are very similar to the main lattice reflections. There is a probable relation between the non-Bragg reflections in cancrinite and the sodalite group of minerals. / Thesis / Master of Science (MSc)

Median in some statistical methods Abstract: This work is focused on utilization of robust properties of median. We propose variety of algorithms with respect to their breakdown point. In addition, other properties are studied such as consistency (strong or weak), equivariance and computational complexity. From practical point of view we are looking for methods balancing good robust properties and computational complexity, be- cause these two properties do not usually correspond to each other. The disser- tation is divided to two parts. In the first part, robust methods similar to the exponential smoothing are suggested. Firstly, the previous results for the exponential smoothing with ab- solute norm are generalized using the regression quantiles. Further, the method based on the classical sign test is introduced, which deals not only with outliers but also detects change points. In the second part we propose new estimators of location. These estimators select a robust set around the geometric median, enlarge it and compute the (iterative) weighted mean from it. In this way we obtain a robust estimator in the sense of the breakdown point which exploits more information from observations than standard estimators. We apply our approach on the concepts of boxplot and bagplot. We work in a general normed vector...

This thesis examines if developers of software can be considered aware of the usage of the product. The study was made to reveal the developers perception about the usage, and comparing their perception with the actual usage. The scope of the study was to investigate a software system used in a contact center, specifically the part of the software where the administration is performed. The first part of the study consisted of interviews with the developers of the software to obtain their perception of the usage. Further, a second study was performed to determine the most important functionalities in the software for the end users, and evaluate the usability of the software. This was achieved by performing a contextual inquiry with end users. The results of the study concluded that the developers could be considered to have a moderate awareness of the usage. Although, the study revealed that the developers had limited understanding of the functionalities that are the most important for the end users. One of the essential functionalities according to the contextual inquiry, was left unmentioned by a majority of the developers. On the basis of Nielsen’s theoretical usability concepts, the usability of the client was evaluated as low, something the developers also were considered aware of. Finally, the study concludes a lack of a profound understanding amongst the developers regarding the difficulties and limitations that the end users face.

The estimated bias and variance of commonly applied and jackknife variance estimators and observed significance level and power of standardised generalized Wilcoxon linear rank sum test statistics and tests, respectively, of Gehan and Prentice are compared in a Monte Carlo simulation study. The variance estimators are the permutational-, the conditional permutational- and the jackknife variance estimators of the test statistic of Gehan, and the asymptotic- and the jackknife variance estimators of the test statistic of Prentice. In unbalanced small sample size problems with right censoring, the commonly applied variance estimators for the generalized Wilcoxon rank test statistics of Gehan and Prentice may be biased. In the simulation study it appears that variance properties and observed level and power may be improved by using the jackknife variance estimator. To establish the sensitivity to gross errors and misclassifications for standardised generalized Wilcoxon linear rank sum statistics in small samples with right censoring, the sensitivity curves of Tukey are used. For a certain combined sample, which might contain gross errors, a relatively simple method is needed to establish the applicability of the inference drawn from the selected rank test. One way is to use the change of decision point, which in this thesis is defined as the smallest proportion of altered positions resulting in an opposite decision. When little is known about the shape of a distribution function, non-parametric estimates for the location parameter are found by making use of censored one-sample- and two-sample rank statistics. Methods for constructing censored small sample confidence intervals and asymptotic confidence intervals for a location parameter are also considered. Generalisations of the solutions from uncensored one-sample and two-sample rank tests are utilised. A Monte-Carlo simulation study indicates that rank estimators may have smaller absolute estimated bias and smaller estimated mean squared error than a location estimator derived from the Product-Limit estimator of the survival distribution function. The ideas described and discussed are illustrated with data from a clinical trial of Head and Neck cancer. / digitalisering@umu

Technische Systeme nutzen sich ab. Dadurch bedingt kommt es zu Ausfällen. Um die Funktionstüchtigkeit von abgenutzten technischen Systemen wiederherzustellen, werden Instandsetzungsmaßnahmen durchgeführt. Da die Folgen eines unerwartet eintretenden Ausfalls drastisch sein können, ist es sinnvoll, das Abnutzungsverhalten eines technischen Systems vorherzusagen und so den Zeitpunkt von Instandsetzungsmaßnahmen zielgerichtet zu planen. Die Erstellung von Abnutzungsprognosen wird dadurch erschwert, dass sich technische Systeme oft variabel, in Abhängigkeit von auf sie einwirkenden Beanspruchungen, abnutzen. Außerdem wird diese Abnutzungsvariabilität von betriebsbedingten Einflüssen überlagert, was deren Modellierung erschwert. Im Rahmen dieser Arbeit wurden deshalb Lösungsansätze entwickelt, die es ermöglichen, die Abnutzungsvariabilität eines technischen Systems in Abnutzungsprognosen zu integrieren und dabei betriebsbedingte Einflüsse zu berücksichtigen. Somit können Instandsetzungsmaßnahmen präziser geplant, Ressourcen geschont sowie Kosten reduziert werden. / Technical systems are prone to deterioration. This leads to negative consequences like break-downs. Maintenance actions are executed in order to transfer technical systems back into healthy states. If break downs occur suddenly, the consequences can be dramatic. Therefore, it is reasonable to schedule maintenance actions based on health-state predictions. Thereby, health state predictions are impeded by the fact that technical systems often deteriorate variably, depending on certain stress factors. Furthermore, the effects of variable deterioration behavior can be hidden by system specific behavior. Thus, approaches are shown which integrate variable deterioration behavior into healthstate predictions while influences caused by the system specific behavior are considered. Consequently, maintenance actions can be scheduled more efficiently which spares resources and reduces costs.