The primary purpose of this study was to examine the correlation between depression and the personal characteristics of Asians who are 50 years or older. The secondary objective was to determine whether Asians 50 years or older living in the United States are more likely to be depressed than other ethnicities. The information for this study was secured from the National Health Interview Survey, spanning the years 2001 to 2010. In this study, I utilized the SAS-Callable SUDAAN statistical system. Multivariate regression was used to predict and determine significant correlations. The results indicated that Asians 50 and older living in the U.S. and who experience functional limitations, poor vision, hypertension, poor health, not married, and unemployed in previous year were in general more prone to depression. Furthermore, the study indicated that Asian elderly living the U.S. showed lower rates of depression than all non- Asian ethnicities. However when controlled for personal characteristics only Whites and Hispanics had higher depression incidences than Asian elderly. Recommendations for future studies include: conducting more micro and macro studies of Asian elders, such as in-depth case studies for each ethnicity, longitudinal studies of various Asian subgroups, and studies of Asian elderly with hypertension who have committed suicide.

Parental depression can interfere with numerous aspects of parents’ lives, including parenting behaviors. Previous research has explored the relationship between past parental depression or current depressive symptoms and negative parenting behaviors. The current study investigates two models of mediation to explain the relationship between parental depression and parenting. In the first, it explores whether mindfulness mediates the relationship between past depression severity and three parenting behaviors: withdrawn/disengaged parenting, low levels of positive parenting and poor monitoring/supervision. In the second, it explores whether mindfulness mediates the relationship between current depressive symptoms and four parenting behaviors: withdrawn/disengaged parenting, low levels of positive parenting, poor monitoring/supervision and inconsistent discipline. The sample draws from two research sites, one in Burlington, Vermont and the other in Nashville, Tennessee and included previously or currently depressed parents (n=121; mean age = 42.5 years, SD = 7.40 years, range = 24-69), and their 9-15 year old children (n=167; mean age = 11.40 years, SD = 2.30 years, range = 9-15). All participating parents and children completed written measures at the time of their initial assessment. The overall findings of this study indicate that parents’ current depressive symptoms, but not past depression severity, increase the risk of low levels of positive parenting and parenting with greater inconsistent discipline, and that these associations are mediated by a parent’s level of mindfulness.

M.A. (Psychology) / Both the theories of Seligman (1975) and Beck (1976) provide an explanation of depression as a cognitive phenomenon. These theories are inadequate in the sense that no provision is made for individual differences and personality factors in the development of depression. This study postulates that perfectionism is related to learned helplessness and depression, with the intention of understanding mild depression. Forty first year students at the Rand Afrikaans University were selected on the basis of exceptionally high or exceptionally low scores on the P.Hs. (Perfectionistic Attitude Scale). The subjects were further divided into helpless and non-helpless groups. Helplessness was induced by confronting the subjects with a cognitive task which was impossible to execute. Hereafter, among other things, the subjects' attributions and level of depression (Beck Depression Inventory) were measured. The findings indicate that perfectionism is significantly related to depression, but not to learned helplessness. Furthermore, it was found that helplessness is not necessarily related to depression. It is suggested that helplessness in a laboratory situation is not aversive or important enough to cause depression. The recommendation is made that future helplessness studies Should preferably concentrate on actual life situations. Perfectionism was found to be an important factor in the development of depression, and it was found that perfectionists are essentially underachievers. The implications of these findings were briefly discussed.

M.A. (Clinical Psychology) / In contrast to the commonly accepted notion that persons with antisocial personality disorders ore characterised by a marked absence of anxiety and depression recent studies have indicated that anxiety and depression. might indeed be found amongst some antisocial personality disorders.Where resistance to psycho-therapeutic treatment was previously ascribed to the lack of anxiety and depression in the antisocial personality disorder, its presence ...

D.Litt.et Phil. / Please refer to full text to view abstract

The current study was conducted to examine the effects of telephone intervention on arthritis self-efficacy, depression, pain and fatigue in older adult patients in different clinical settings. Eighty-five subjects from two clinics were randomly assigned to either the control (n = 45) or intervention (n = 40) groups. The study was a mixed quantitative/qualitative design. Each subject completed several pre-tests including the Arthritis Self-Efficacy (ASE) scale, the Geriatric Depression scale (GDS), and numeric rating scales for both pain and fatigue. All subjects received an informational packet on self-management of arthritis and developed an action plan and personal goals for self-management of their arthritis over the next six weeks. Subjects in the intervention groups also received a brief educational session on the packet and were called once weekly for the next five weeks. The calls followed a script, addressing different sections of the informational packet. The calls were designed to be both instructional and motivational. Subjects in the control groups were not contacted until the sixth week. At that time all subjects were called and the assessment tools were re-administered. Quantitative data analysis (repeated measures ANOVA) showed a significant increase in ASE scores over time for both intervention and control groups. Qualitative data analysis revealed the emergence of several major themes that were supported by the subjects' responses. The telephone interventions helped many of the participants initiate exercise programs for the first time in their lives. Participants also indicated that they were determined to adhere to these programs, that they would make other lifestyle changes that would assist their arthritis self-management, and that the telephone interventions were helpful in facilitating medical care for arthritis exacerbations and other medical problems. Telephone intervention was helpful in promoting adherence to exercise programs and other lifestyle changes that may assist older patients in the self-management of their arthritis, and was helpful in facilitating medical care. Arthritis education classes have been developed which have been shown to enhance the self-management of arthritis in older patients. Telephone intervention may be an alternative means of enhancing self-management for these individuals.

Of the millions of American workers who suffered economically during the Great Depression of the 1930s, musicians in particular fell on hard times. The live music profession had begun to decline even before the onset of the Depression due to the introduction of new acoustic technologies. In 1935, President Franklin Delano Roosevelt established the Works Progress Administration (WPA) in an attempt to put the nation back to work through governmentsponsored work projects. One division of the WPA was Federal Music Project (FMP). A great deal has been written about the WPA, but the Music Project has received little scholarly attention, leaving the stories of musicians in New Orleans and other cities largely untold. This study argues that the Federal Music Project in New Orleans was an unusually successful program due to the special talents of its administrators, the rich pre-existing musical heritage of the city, and the generally positive interaction between the people of New Orleans and the FMP.

This thesis is not intended for those who regard practical problems as something to be talked about. It is not for those who believe that every question has an objective, absolute, or interpretable answer. It is not intended for the individual who knows what happiness is, in that the very definition of happiness is not to be found; at best only suggested. It is not intended solely for Eastern thought. It is not intended solely for Western thought - it is intended for both. Most importantly, this thesis attempts to exclude the esoteric language common in the philosophical discipline. Arthur Schopenhauer once said that one should use common words to say uncommon things. This thesis is intended for both the common and the uncommon reader, as is the subject - Happiness. Simply stated, this thesis is an exploration into why the contemporary notion of how one should best pursue happiness is flawed. This exploration shall encompass a vast array of subjects, many now far departed from the philosophical tradition. In by neglecting these deeper, sometimes more intimate forms of inquiry, is to waste a central resource for the study of philosophy; let alone a study on happiness. From this, I take a particular interest in culture. And, regarding America's contemporary culture, I hold, that we make a distinction between behaviors that bring true happiness and behaviors that only make you feel happy. For this reason, my thesis is as followed: The 21st century’s primary conflict is not the poverty in plenty but the unhappiness brought in the pursuit of pleasure by most. I hold that the current American model of what brings happiness is in direct contradiction to what it takes for actually being happy. In short, there is ongoing contradiction between restraint and freedom, between adversity and fulfillment, and between the individual and the whole. We pursued freedom but we now live in a world that is more monitored, and more subjected to a network of small complicated rules that strangle freedom. We pursued happiness and it leads to resentment, it leads to pathological disease, and it leads to even more unhappiness. We pursed happiness within, and forget that happiness is only real when shared. In sum, my attempt is to elucidate the themes, problems, and contradictions within today’s pursuit disclosed on the - Horizon of Happiness.

Recovery from the Great Depression began in March 1933, simultaneous to Franklin Roosevelt's inauguration. However, the pace of that recovery between that date and the Second World War was extremely uneven with some dramatic starts and stops. Between March and July 1933, manufacturing production rose 78%, production of durable goods was up 199%, total industrial production rose 57%, and the Dow Jones Industrial Average rose 71%.Then the economy contracted sharply again beginning in August 1933-the July 1933 level of industrial production was not reached again until August 1935. This paper addresses two questions. What factors were responsible for bringing about the sharp recovery in the spring of 1933 and what factors brought this short-lived economic surge to an end? (C) 2016 Elsevier Inc. All rights reserved.

Galanin is a 29/30 amino acid long bioactive peptide discovered over 30 years ago when C-terminally amidated peptides were isolated from porcine intestines. The name galanin originates from a combination of the first and last amino acids - G from glycine and the rest from alanine. The first 15 amino acids are highly conserved throughout species, which indicates that the N-terminus is important for receptor recognition and binding. Galanin exerts its effects by binding to three different G protein-coupled receptors, which all differ according to regional distribution, the affinity for shortened galanin fragments, as well as the intracellular G-protein signaling cascade used. When first discovered, galanin was found to cause muscle contraction as well as hyperglycemia.  Over the years, galanin has been reported to be involved in a wide variety of biological functions, for example food intake and neurogenesis, and pathological functions, for example epilepsy and depression. Determining the specific involvement of the three different galanin receptors in biological and pathological processes is limited by the small amount of galanin receptor selective/specific ligands available as research tools. Furthermore, the fast degradation of peptides limits the administration routes in animal studies. This thesis aims at developing new galanin receptor-selective ligands to help delineate the involvement of the three different galanin receptors. Paper 1 presents the shortest galanin fragment with a galanin receptor 2 specific binding preference where only a single amino acid substitution was made, Ala5Ser in galanin (2-11). In addition, G-protein coupled receptor signaling were evaluated through both a classical second messenger assay and a real-time label-free technique in cells overexpressing the receptor as well as low receptor expression. Paper 2 demonstrates that the neuroprotective effects of galanin in a kainic acid-induced excitotoxic animal model were mediated through galanin receptor 1. Furthermore, a new robust protocol for evaluating G-protein signaling using a label-free real time impedance technique was presented and compared to two different classical second-messenger assays. Paper 3 presents a series of systemically active galanin receptor 2 selective ligands subsequently evaluated in two different depression-like animal models. Paper 4 investigates a mutated form of human galanin which was found in epilepsy patients and binding and signaling properties of the mutated associated ligand p.(A39E) was examined. In conclusion, this thesis presents the discovery of eight new galanin ligands, which can be used to evaluate the galaninergic system as well as to help investigate the possible use of peptides as pharmaceuticals in different diseases.