Nos eqüinos, as articulações sinoviais são submetidas a graus variáveis de estresse físico, de acordo com o tipo de movimento executado. Com o trabalho ou treinamento intenso, o aumento da carga imposta aos seus tecidos pode provocar sinovite mecanicamente induzida, com produção e liberação de citocinas, e conseqüentemente estimulação de metaloproteinases e de outros componentes inflamatórios. Estes eventos podem acarretar em desequilíbrio entre os processos de síntese e degradação de proteoglicanos e glicosaminoglicanos da matriz cartilagínea, levando a osteoartrite. Perante a magnitude de ocorrência de osteoartrite em eqüinos atletas, teve-se como objetivo caracterizar a população de cavalos, com diagnóstico firmado de osteoartrite, atendida junto ao Serviço de Clínica Médica de Eqüinos do Hospital Veterinário (HOVET) da Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ/USP), em um período de 10 anos. O levantamento da casuística foi executado através da análise de fichas de registro dos casos antigos. A amostragem foi composta envolvendo a totalidade de casos de eqüídeos, com diagnóstico firmado da doença articular, arrolando-se e analisando-se dados referentes a: espécie, idade, sexo, peso, raça, atividade esportiva, início e evolução da doença, tipo de manifestação clínica, e exames radiográficos. Foram analisados 152 prontuários de eqüídeos acometidos por osteoartrite. Observou-se que a maioria tratava-se de animais da espécie eqüina, com idade média de 8 anos, macho ou fêmea, das raças Quarto de Milha, Mangalarga Paulista e sem raça definida, pesando em torno de 420kg, praticantes de romaria ou provas de Quarto de Milha.O tempo médio entre o início da sintomatologia de osteoartrite e o atendimento hospitalar foi de 7,7 meses.A análise estatística não mostrou relação entre presença de claudicação, dor palpável, sensibilidade em casco, sensibilidade muscular, teste de flexão positiva e atividade exercida (p>0,05). Porém, mostrou correlação entre a presença de edema/calor e atividade exercida (p<0,05). Também não mostrou relação entre dor palpável, edema/calor, sensibilidade de casco, sensibilidade muscular, e claudicação (p>0,05). Mediante os resultados obtidos pela avaliação radiográfica dos pacientes acometidos por osteoartrite, notou-se que não houve relação direta entre o menor e maior escore em relação à presença ou não de claudicação. Concluiu-se que o perfil do paciente, acometido por osteoartrite, mais freqüentemente atendido pelo Serviço de Clínica Médica de Eqüinos ? HOVET ? USP trata-se da espécie eqüina, da raça Quarto de Milha, 8 anos de idade, 420 kg, praticante de provas de Quarto de Milha. / The equine sinovial joints are submitted do different degrees of physical stress, depending on the movement performed. With work and hard training, the increase on the loads applied to its tissues maycause mechanically induced synovitis, with production and release of cytokines, and consequently metalloproteinases stimulation and other inflammatory components. These events may lead to anunbalance between the synthesis and degradation processes, of proteoglycan and glicosaminoglycan of the cartilaginous matrix, leading to the osteoarthritis. Regarding the magnitude of the osteoarthritis incidence on athletic horses, our goal is to characterize the horse population with confirmed osteoarthritis diagnoses examined by the Equine Internal Medicine Service at the Veterinary Hospital at the College of Veterinary Medicine and Animal Science of University of São Paulo, in a 10 year period. The retrospective study was performed through the analysis of documented cases. The sampling included the totality of equide cases with confirmed joint disease diagnosis and analyzed considering: age, sex, breed, sportive activity, beginning and evolution of the disease, clinical signs observed and radiographic exam. One hundred and fifty two (152) equides hospital forms with confirmed osteoarthritis were analyzed .It was found that most cases were equines, with an average age of 8 years, either male or female, with the predominance of Quarter Horses, Mangalarga Paulista and Mixed Breds, weighing around 420Kg, used for long distance rides or western activities. The average time between the beginning of the osteoarthritis clinical signs and the referring to the hospital was 7,7 months. The statistical analysis did not show relation between lameness, palpable pain, hoof sensitivity, muscular pain, positive flexion test and use (p>0,05). Although, its howed a relation between edema /heat and use (p<0,05). No relation was found between palpable pain, edema/heat, hoof and muscular pain and lameness (p<0,05). The results found in the radiographic evaluation of the animals with osteoarthritis showed no direct relation between the radiographic score and lameness. The animals with osteoarthritis more frequently sent to the Equine Internal Medicine Service -HOVET-USP, is equine , Quarter Horse, 8 years old, 420Kg, used in western competitions.

Submitted by Erika Demachki (erikademachki@gmail.com) on 2015-02-03T18:48:53Z No. of bitstreams: 2 Dissertação - Yoná Serpa Mascarenhas - 2014.pdf: 2274347 bytes, checksum: 77b157715fb3e4c58f0ad28e8e15e9b2 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) / Approved for entry into archive by Erika Demachki (erikademachki@gmail.com) on 2015-02-03T18:49:13Z (GMT) No. of bitstreams: 2 Dissertação - Yoná Serpa Mascarenhas - 2014.pdf: 2274347 bytes, checksum: 77b157715fb3e4c58f0ad28e8e15e9b2 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) / Made available in DSpace on 2015-02-03T18:49:13Z (GMT). No. of bitstreams: 2 Dissertação - Yoná Serpa Mascarenhas - 2014.pdf: 2274347 bytes, checksum: 77b157715fb3e4c58f0ad28e8e15e9b2 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) Previous issue date: 2014-02-26 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES / The objective of the study was to identify and describe the visual symptoms in seedlings of tomato processing, stemming from lack of macro and micronutrients and determine biometric attributes that stage. For this, using two hybrid (N901 and H9553) conducted an experiment in a agricultural greenhouse, in randomized complete block and in factorial arrangement with four replications. The treatments are composed of fourteen nutrient solutions as follows : full/control and the solutions with omitting isolated nutrients (-N, -P, -K, -Ca, -Mg, -S, -B, -Cu, -Fe, -Mn, -Mo, -Zn) and only deionized water. Held sowing in trays with substrates for later transplanting for phenolic foam. Daily treatments to be applied and/or deionized water solutions. For 30 days of experiment was realized the analysis and records the evolution of nutritional deficiency symptoms. The results showed that the omission of isolated nutrient committed to quality seedlings, leading to morphological changes. The first symptoms developed on seedlings grown under omission, N and deionized water, Fe and Ca, respectively. The dry mass decreased in all treatments, except in the absence of B, with the following order of reduction: deionized water = N > Ca > K = P = S = Fe > Mg = Mn = Mo > Complete = Cu = Zn > B. These results are different from those found in the literature of adult plants. There was not interaction between the solutions and the hybrids, however the H9553 was more sensitive to nutritional deficiencies. / O objetivo do estudo foi identificar e descrever os sintomas visuais em mudas de tomate para processamento industrial, decorrentes da carência de macro e micronutrientes e determinar atributos biométricos nessa fase. Para isso, utilizando dois híbridos (N901 e H9553) foi conduzido um experimento em estufa agrícola, em blocos casualizados e arranjo fatorial com quatro repetições e quatorze soluções nutritivas configurando os tratamentos: completa/controle e as soluções com omissão isolada dos nutrientes (-N, -P, -K, -Ca, -Mg, -S, -B, -Cu, -Fe, -Mn, -Mo, -Zn) e somente água deionizada. Realizou-se o semeio em bandejas com substratos para posterior transplantio para espuma fenólica. Diariamente aplicavam-se soluções tratamentos e/ou água deionizada. Durante 30 dias foram realizadas analises descritivas e registros da evolução dos sintomas de deficiência nutricional. Os resultados mostraram que a omissão isolada dos nutrientes comprometeu a qualidade das mudas, levando a alterações morfológicas. Os primeiros sintomas se manifestaram em plântulas cultivadas com omissão de N e água deionizada, Fe e Ca, nessa ordem. A fitomassa seca mostrou uma redução em todos os tratamentos, exceto sob ausência de B, apresentando a seguinte ordem de redução: água deionizada=N > Ca > P = K = S = Fe > Mg = Mn = Mo > Completa = Cu = Zn > B. Estes resultados diferem dos encontrados na literatura para plantas adultas. Não houve interação entre soluções e híbridos, porem o H9553, mostrou-se mais sensível às deficiências nutricionais.

A pesquisa visou avaliar a metodologia do projeto Tree Vis para determinar a nutrição de ferro, boro, zinco e cobre em plantas de milho submetidas a doses desses nutrientes. Foram utilizados tratamentos constituídos pela omissão, 1/5, 2/5 e a dose completa dos elementos com quatro repetições em cada fase de coleta, sendo essas V4, V7 e R1. Os experimentos foram realizados em casa de vegetação, em cultivo hidropônico, conduzidos em vasos com solução nutritiva. Foi determinada a produção de massa seca da parte aérea e do sistema radicular, além da determinação dos teores dos nutrientes nas folhas indicativas dos estádios fenológicos de cada época de coleta. Em cada estádio foram coletadas imagens das folhas indicativas e novas através de um scanner para as análises de visão artificial. As doses crescentes dos nutrientes promoveram maior produção de massa seca na parte aérea e nas raízes e reduziram a produção quando utilizada a dose máxima do nutriente. O sistema de visão artificial mostrou-se promissor na identificação de deficiência de ferro com 77,5% de acerto, boro com 81,7% de acerto, zinco com 81,0% e cobre com 57,2 % de acerto, tendo identificado as com boa confiabilidade. / The research aimed to evaluate the methodology of the Pr oject Tree Vis for determining nutrition iron, boron, zinc and copper in maize plants subjected to doses of these nutrients. Treatments used were made by omission, 1/5, 2/5 and the full dose of the elements with four replicates at each stage of collection, these are V4, V7 and R1. The experiments ware conducted in a greenhouse in hydroponics, conducted in pots with nutrient solution. Was determined the dry mass production of the aerial part and roots, besides the determ ination of nutritional content in the leaves indicative of phenological stages of each harvest time. At each stage were collected images of indicative and new leaves through with a scanner for the analyzes of artificial vision. The increasing doses of nutr ients promoted higher dry mass production in the aerial part and roots and reduced the production when using the highest dose of the nutrient. The artificial vision system showed promise in identifying of deficiency of iron with 77.5% accuracy, of boron with 81.7% of correct, of zinc with 81.0% accuracy and copper with 57.2% accuracy, with a good reliability in the identifi.

O Zucchini lethal chlorosis virus (ZLCV) é uma espécie do gênero Tospovirus, transmitido por tripes, que infecta diversas espécies da família Cucurbitaceae. Já foi constatado em diversos estados brasileiros e sua incidência tem aumentado significativamente nos últimos anos em algumas regiões. Por se tratar de uma virose em potencial para as cucurbitáceas, pouco se conhece sobre os danos causados e a reação das diferentes espécies de cucurbitáceas à infecção em campo. Esse trabalho teve por objetivos: estudar a eficiência da RT-PCR para a detecção rápida e especifica do ZLCV em cucurbitáceas; avaliar os danos causados pelo ZLCV em abobrinha de moita em campo e a reação de sete espécies/variedades de cucurbitáceas à infecção natural A detecção do ZLCV por RT-PCR foi estudada utilizando um par de oligonucleotídeos iniciadores, desenhados com base na seqüência do S-RNA do ZLCV (AF067069). Quatro espécies de tospovírus (TSWV, TCSV, GRSV e CSNV) e outros vírus que infectam cucurbitáceas (PRSV-W-1, PRSV-W-C, ZYMV-M, ZYMV-Atibaia e CMV) foram incluídos no teste. Na reação de RT-PCR foi obtido um fragmento de aproximadamente 350 pb, amplificado somente a partir de RNA total extraído de planta infectada com o ZLCV. A seqüência obtida desse fragmento apresentou 98,2 % de identidade com a seqüência de nucleotídeos do S-RNA do ZLCV depositada no GenBank. Os danos causados pelo ZLCV em abobrinha de moita &#39;Caserta&#39; foram avaliados em campo na ESALQ/USP, Piracicaba-SP, onde esse vírus é freqüente. As plantas foram monitoradas semanalmente quanto à infecção pelo ZLCV por meio dos sintomas e por PTA-ELISA. As plantas foram agrupadas em função da época de aparecimento dos sintomas do ZLCV, avaliando a produção de frutos comerciais (FC) e não comerciais (FNC) de cada grupo e comparando com a de plantas que permaneceram sem sintomas até o final do experimento. As plantas que apresentaram sintomas até os 23 dias após a emergência (DAE) não produziram qualquer tipo de frutos. FC foram colhidos de plantas que apresentaram sintomas a partir dos 42 DAE. Mesmo assim, houve redução de 78,5 % na produção de FC. Plantas que mostraram sintomas por ocasião da última colheita (55 DAE) apresentaram redução na produção de FC de 9,6 %. A infecção com o ZLCV até o início da frutificação inviabiliza a produção de FC de abobrinha de moita &#39;Caserta&#39;. A reação de sete espécies/variedades de cucurbitáceas à infecção com o ZLCV foi avaliada em campo, por meio da infecção natural e em casa de vegetação, onde as plantas foram duplamente inoculadas mecanicamente com o ZLCV no estádio cotiledonar. A avaliação foi feita com base no monitoramento dos sintomas e por PTA-ELISA. A abobrinha de moita &#39;Caserta&#39; e a abóbora híbrida &#39;Takaiama&#39; apresentaram alta suscetibilidade ao ZLCV. O pepino &#39;Safira&#39; apresentou baixa infecção em campo e intermediária em casa de vegetação. Enquanto que a melancia &#39;Crimson Sweet&#39;, o maxixe do Norte, a abóbora rasteira &#39;Menina Brasileira&#39; e a moranga &#39;Alice&#39; apresentaram valores menores de infecção. A moranga &#39;Exposição&#39; foi altamente resistente, pois não foi infectada nos ensaios em campo e em casa de vegetação. / Zucchini lethal chlorosis virus is a specie of the Genus Tospovirus, transmitted by thrips (Frankliniella zucchini), which infects some species of the family Cucurbitaceae. The occurrence of this Tospovirus has already been reported for several Brazilian states and its incidence in cucurbit crops has increased in the last years in some regions. Considering the importance of this Tospovirus for cucurbit crops, very little is known about the damage caused by this virus and the reaction of the different species of cucurbits to infection. This work aimed: to study the efficiency of the RT-PCR for the fast and specific detection of ZLCV, to evaluate the damage caused by this virus on zucchini squash under field condition and the reaction of seven species/varieties of cucurbits to infection with this Tospovirus. The detection of ZLCV by RT-PCR was studied using a pair of primers designed based on the nucleotide sequence of the SRNA of ZLCV (AF067069). Four other Tospovirus species (TSWV, TCSV, GRSV and CSNV) and other virus that infect cucurbits (mild strain PRSV-W-1, wild strain PRSV-WC, mild strain ZYMV-M, wild strain ZYMV-Atibaia and CMV) were included in this test. The RT-PCR reaction generated a fragment of approximately 350 bp, only amplified from total RNA extracted from plant infected with ZLCV. The sequence of this fragment presented 98.2 % identity with the corresponding nucleotide sequence of the S-RNA of ZLCV deposited in the GenBank. The damage caused by ZLCV on zucchini squash (Cucurbita pepo cv. Caserta) was evaluated under field condition. Zucchini squash plants were weekly monitored for the presence of characteristic symptoms induced by ZLCV and PTA-ELISA for virus indexing. Plants were grouped based on the time the symptoms were first seen. Fruits harvested from each plant within each group were classified on marketable (M) and non-marketable (NM) based on the phenotype. Plants that did not show symptoms by the end of the crop were considered still healthy and their yield was used as control. Zucchini squash plants that showed symptoms of ZLCV infection up to 23 days after emergency (DAE) did not yield any fruit. Marketable fruits were first harvested only from plants that showed symptoms 42 DAE. However, the yield of marketable fruits was reduced by 78.5 %, as compared to that from asymptomatic plants. Plants that showed symptoms 55 DAE showed a reduction on the yield of marketable fruit of 9.6%. The reaction of seven species/varieties of cucurbits to infection with ZLCV was evaluated under field and greenhouse conditions. In the field experiment, ZLCV infection occurred naturally. In the greenhouse, plants were twice mechanically inoculated with ZLCV at the cotyledonal stage. Evaluations were based on symptoms expression and PTA-ELISA. Zucchini squash &#39;Caserta&#39; and hybrid squash &#39;Takaiama&#39; were highly susceptible. The cucumber &#39;Safira&#39; presented low percentage of infected plants in the field and intermediate in the greenhouse. Watermelon &#39;Crimson Sweet&#39;, northern gherkin, long neck squash &#39;Menina Brasileira&#39; and winter squash &#39;Alice&#39; presented lower values of infected plants. Winter squash &#39;Exposição&#39; was highly resistant to infection under field and greenhouse conditions.

Made available in DSpace on 2016-01-26T18:56:25Z (GMT). No. of bitstreams: 1 CARLOS_DISSERTACAO_AGRONOMIA_31_05_2012.pdf: 1729858 bytes, checksum: c9d12bae435ce85af2fa614993043588 (MD5) Previous issue date: 2012-05-15 / The aim of this study was to establish norms of the Diagnosis and Recommendation Integrated System (DRIS) in the culture of banana (Musa sp) for the subgroup Cavendish. We used 107 leaf samples from plants on farms in the towns of Andirá and Rancho Alegre, both located in Northern Paraná State, cultivars Nanicão and Grande Naine , with and without irrigation, aged 2 to 10 years. Chemical analysis determined the content of leaf 11 nutrients N, P, K, Ca, Mg, S, B, Cu, Fe, Mn and Zn. DRIS norms have been established for less than average productivity of 75 t ha-1, where it was found differences between the patterns of levels of nutrients and DRIS norms developed in this study. It was recommended the need for reprogramming of the quantities of fertilizer to be used according to the results obtained for the N, Ca, Mg, S, Fe and Zn contents presenting below the pre-established standards tracks. / O objetivo do presente trabalho foi estabelecer normas do Sistema Integrado de Diagnose e Recomendação (DRIS) na cultura da banana (Musa sp) para o sub grupo Cavendish. Foram utilizadas 107 amostras foliares de plantas em lavouras situadas nos municípios de Andirá e Rancho Alegre, ambos localizados na Região Norte do Estado do Paraná, cultivares Nanicão e Grande Naine , com e sem irrigação, idade variando entre 2 a 10 anos. As análises químicas foliares determinaram os teores de 11 nutrientes: N, P, K, Ca, Mg, S, B, Cu, Fe, Mn e Zn. Normas DRIS foram estabelecidas para produtividade média igual ou superior a 75 t ha-1, onde constatou-se divergências entre os teores padrões dos nutrientes e os teores das normas DRIS estabelecidas neste estudo. Recomendou-se a necessidade de reprogramação das quantidades a serem utilizadas de fertilizantes de acordo com os resultados obtidos, para N, Ca, Mg, S, Fe, e Zn que apresentaram índices abaixo das faixas padrões pré estabelecidas.

Made available in DSpace on 2016-07-18T17:51:09Z (GMT). No. of bitstreams: 1 CARLOS_DISSERTACAO_AGRONOMIA_31_05_2012.pdf: 1729858 bytes, checksum: c9d12bae435ce85af2fa614993043588 (MD5) Previous issue date: 2012-05-15 / The aim of this study was to establish norms of the Diagnosis and Recommendation Integrated System (DRIS) in the culture of banana (Musa sp) for the subgroup Cavendish. We used 107 leaf samples from plants on farms in the towns of Andirá and Rancho Alegre, both located in Northern Paraná State, cultivars Nanicão and Grande Naine , with and without irrigation, aged 2 to 10 years. Chemical analysis determined the content of leaf 11 nutrients N, P, K, Ca, Mg, S, B, Cu, Fe, Mn and Zn. DRIS norms have been established for less than average productivity of 75 t ha-1, where it was found differences between the patterns of levels of nutrients and DRIS norms developed in this study. It was recommended the need for reprogramming of the quantities of fertilizer to be used according to the results obtained for the N, Ca, Mg, S, Fe and Zn contents presenting below the pre-established standards tracks. / O objetivo do presente trabalho foi estabelecer normas do Sistema Integrado de Diagnose e Recomendação (DRIS) na cultura da banana (Musa sp) para o sub grupo Cavendish. Foram utilizadas 107 amostras foliares de plantas em lavouras situadas nos municípios de Andirá e Rancho Alegre, ambos localizados na Região Norte do Estado do Paraná, cultivares Nanicão e Grande Naine , com e sem irrigação, idade variando entre 2 a 10 anos. As análises químicas foliares determinaram os teores de 11 nutrientes: N, P, K, Ca, Mg, S, B, Cu, Fe, Mn e Zn. Normas DRIS foram estabelecidas para produtividade média igual ou superior a 75 t ha-1, onde constatou-se divergências entre os teores padrões dos nutrientes e os teores das normas DRIS estabelecidas neste estudo. Recomendou-se a necessidade de reprogramação das quantidades a serem utilizadas de fertilizantes de acordo com os resultados obtidos, para N, Ca, Mg, S, Fe, e Zn que apresentaram índices abaixo das faixas padrões pré estabelecidas.

Please read the abstract in the section 00front of this document Please cite as follows: Opperman JA, 2002, Die emosionele belewenis van 'n beenmurgoorplanting : 'n Maatskaplike Werk perspektief, MA dissertation, University of Pretoria, Pretoria, viewed yymmdd < http://upetd.up.ac.za/thesis/available/etd- 07252005-110248/ > / Dissertation (MA (Social Work))--University of Pretoria, 2002. / Social Work and Criminology / MA (Social Work) / unrestricted

Inherited disorders of platelet function are a rare and heterogeneous group of diseases usually characterised by a mild to moderate bleeding tendency. Typical bleeding symptoms are easy bruising, epistaxis, menorrhagia as well as mucocutaneous and perioperative bleeding. The performance of platelet function diagnostics in children is hampered by age-dependent restriction of blood sample size, poor venous access, and the lack of reproducible test reference ranges for children of different age groups. Platelet function testing is limited to specialised centres, because platelet function test procedures are complicated and time-consuming, which most likely results in a relevant number of undiagnosed and incorrectly classified children with clinically relevant platelet function defects. Evaluation of bleeding history and bleeding symptoms is essential for a rational step-bystep approach to diagnosis. Platelet function diagnostics should be preceded by the exclusion of thrombocytopenia, von Willebrand disease, and secondary haemostasis defects. Light transmission aggregometry is still considered the standard for the assessment of platelet function. Every effort should be made to classify the specific platelet function defect in the patient, because this is essential for accurate treatment and counselling. / Angeborene Thrombozytenfunktionsstörungen stellen eine seltene und heterogene Gruppe von Erkrankungen dar, welche meist durch eine leichte bis mittelschwere Blutungsneigung auffallen. Typische Blutungssymptome sind Hämatomneigung, Epistaxis, Menorrhagien sowie Schleimhaut- und perioperative Blutungen. Die Durchführung der Thrombozytenfunktionsdiagnostik bei Kindern wird erschwert durch die altersabhängig begrenzte Blutprobenmenge, schwierige Venenverhältnisse und das Fehlen von Referenzbereichen für Kinder unterschiedlichen Alters. Aufgrund der meist komplizierten und zeitaufwendigen Tests ist die Thrombozytendiagnostik auf spezialisierte Zentren begrenzt. Mit hoher Wahrscheinlichkeit wird eine relevante Anzahl von Kindern mit nichtdiagnostizierten bzw. unkorrekt klassifizierten, klinisch relevanten Thrombozytopathien übersehen. Die Erhebung der Blutungsanamnese und die Bewertung der Blutungssymptome sind erforderlich für eine stufenweise erfolgreiche Gerinnungsdiagnostik. Vor Durchführung einer Thrombozytenfunktionsdiagnostik sollten das Vorliegen einer Thrombozytopenie, einer von-Willebrand-Erkrankung und sekundärer Gerinnungsstörungen ausgeschlossen werden. Die Lichttransmissionsaggregometrie gilt noch immer als Standardmethode für die Beurteilung der Thrombozytenfunktion. Nach Möglichkeit sollte stets versucht werden, den vorliegenden spezifischen Thrombozytenfunktionsdefekt zu klassifizieren, da dies für eine adäquate Behandlung und eine gezielte genetische Beratung notwendig ist. / Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.

Automotive diagnosis data are useful for the automotive OEMs and third parties in order to analyze the vehicle performance and driving behavior. This data can be access and read in real time situation using the On-Board Diagnosis system which is located inside the vehicle and is accessible by its socket. However, as the diagnosis data are in real time and not being stored, analyzing them is not easy. Therefore, in this project, a program on Raspberry Pi will be developed which is going to read diagnosis data and store them in a cloud database. The cloud database will handle the data storage and keep the data for further analysis and evaluations. The database will be accessible everywhere as it is using cloud technology. On the other hand, in order to provide easy and meaningful access to the data, a web application is developed in order to visualize the data by means of Graphs, Texts, and maps.

Background: Although the relationship between body weight and blood pressure (BP) is well established, there is a lack of data regarding the impact of obesity on the prevalence of hypertension in primary care practice. The objective of this study was to assess the prevalence of hypertension and the diagnosis, treatment status, and control rates of hypertension in obese patients as compared to patients with normal weight. Methods: A cross-sectional point prevalence study of 45,125 unselected consecutive primary care attendees was conducted in a representative nationwide sample of 1912 primary care physicians in Germany (HYDRA). Results: Blood pressure levels were consistently higher in obese patients. Overall prevalence of hypertension (blood pressure ≥140/90 mm Hg or on antihypertensive medication) in normal weight patients was 34.3%, in overweight participants 60.6%, in grade 1 obesity 72.9%, in grade 2 obesity 77.1%, and in grade 3 obesity 74.1%. The odds ratio (OR) for good BP control (<140/90 mm Hg) in diagnosed and treated patients was 0.8 (95% confidence interval [CI] 0.7– 0.9) in overweight patients, 0.6 (95% CI 0.6–0.7) in grade 1, 0.5 (95% CI 0.4–0.6) in grade 2, and 0.7 (95% CI 0.5– 0.9) in grade 3 obese patients. Conclusions: The increasing prevalence of hypertension in obese patients and the low control rates in overweight and obese patients document the challenge that hypertension control in obese patients imposes on the primary care physician. These results highlight the need for specific evidence-based guidelines for the pharmacologic management of obesity-related hypertension in primary practice.