Electronic theses and dissertations (ETDs) are an evolving genre of graduate student research that is gaining widespread acceptance among universities in the international community. ETDs are also beginning to diffuse slowly among American universities; however, a number of issues continue to work against more rapid adoption among intitutions in the United States. This dissertation examines ETDs as an evolving electronic research genre by (1) historicizing the situated development of its predecessor, the traditional print dissertation, in nineteenth century German and American Universities; (2) reporting on the current state of the Networked Digital Library of Electronic Theses and Dissertations, an initiative of Virginia Polytechnic University; (3) analyzing ETDs as a technological innovation undergoing the diffusion process according to Emmet Roger's Diffusion of Innovation Theory; and (4) presenting the results of an ETD pilot project case study carried out at the University of South Florida.

The dissertation is devoted to analysis of current practice and trends in providing repositories of electronic theses and dissertation (ETDs) in terms of their management, searching and dissemination. The first part presents terminology and the current state of access to ETDs in Czech and foreign repositories and includes results of a survey of the state of access to ETDs in the Czech Republic which was completed in 2014 by all public universities. In the second part, a metadata standard is presented, particularly the possibility of mapping EVSKP-MS metadata elements to other metadata formats and utilization within the OAI-PMH protocol. The issue of access to ETDs is dealt with further in terms of metrics for an evaluation of usage of distributed ETDs. Searching for ETDs is also described in case studies as are recommendations for public tenders for a discovery service and for creating an ETD metadata search server and an associated user interface with faceted search. The final part of the thesis focuses on the issue of plagiarism. This incorporates a presentation and analysis of the most important plagiarism detection systems and a case study of the development of the portal Validátor VŠE to provide access to results of document analysis.

Erythroid terminal differentiation couples sequential cell divisions with progressive reductions in cell size. The erythropoietin receptor (EpoR) is essential for erythroblast survival, but its other functions are not well characterized. I used Epor−/− mouse erythroblasts endowed with survival signaling to identify novel non-redundant EpoR functions. I found that, paradoxically, EpoR signaling increases red cell size while also increasing the number and speed of erythroblast cell cycles. Specifically, I found that high levels of EpoR signaling increase the size and shorten the cycle of early erythroblasts, which are amongst the fastest cycling somatic cells. I confirmed the effect of erythropoietin (Epo) on red cell size in human volunteers, whose mean corpuscular volume (MCV) increases following Epo administration. Our work shows that EpoR signaling alters the expected inverse relationship between cell cycle length and cell size. Further, diagnostic interpretations of increased MCV should now include high Epo levels and hypoxic stress. The ability of EpoR signaling to increase cell size in rapidly cycling early erythroblasts suggests that these cells have exceptionally efficient EpoR-driven mechanisms for growth. I found evidence for this in ongoing work, where Epor−/− and Stat5−/− single-cell transcriptomes show dysregulated expression of ribosomal proteins and rRNA transcription and processing genes. Global rates of ribosomal rRNA transcription and protein synthesis increase in an EpoR dependent manner during a narrow developmental window in early ETD, coincident with the time of cell cycle shortening. Our work therefore suggests EpoR-driven regulation of ribosome biogenesis and translation orchestrating rapid cycling and cell growth during early ETD.

No description available.

The aim of this study was to identify what were the requirements placed on the design of distance education programmes as regards discipline or dialogue and how did these factors impact on student-support in the South African National Defence Force (SANDF). Education in general is used to classical behavioural objective that outlines precisely for the student what has to be done and is one way of structuring the learning materials. The South African National Defence Force (SANDF), by its very nature, is very familiar with this formal structure and style of doing things. It prescribes the way teaching has to happen and how the outcomes have to be achieved and at times in a very formal way. Opposed to the above is dialogue that calls for a move away from the prescriptiveness of doing something. Doing and thinking now becomes more open through dialogue. Education stakeholders now debate the value of certain content, since content is no more fixed, the admission of students into the programme is not fixed any more and the way examinations are set is also not fixed or prescriptive. There is now a move away from the disciplinary way of thinking, that is, thinking in terms of fixed boundaries or discipline any longer – dialogue has opened up options and opportunities. This research is based on the belief that distance education problems in the Department of Defence (DoD) are as result of outdated and inadequate instructional or programme design methods or approaches, and thus lack student-support. The four sub-research questions that emanate from the main research question as posed in this research are summarized as follows: (1) What is the distance learning teaching and learning character of the South African National Defence Force (SANDF)? (2) What is the role dialogue in the design of teaching and learning? (3) How are ‘outcomes’ in transactional distance or dialogue achieved? (4) What is the role of dialogue in student empowerment or student support? The design of this research was based on qualitative approach. The feasibility of the research was assured by focusing on distance learning institutions and practitioners. Literature study and document analysis was utilized as data-collection method. Face-to-face interviews with focused groups and individual interviews utilizing unstructured, open-ended questions on interview schedules were also conducted. In addition, anonymous student reports collected by programme managers at the end of a programme replaced the unavailability of student interviews were utilised. The findings of the study were that the character of structural design of distance learning programmes in the South African National Defence Force (SANDF) resembles that of the disciplinary approach, and is thus prescriptive. Structure, in terms of the teaching and learning strategies and the substance of the content is largely the mode of practice in the SANDF’s distance education system. Communication finds its way into the distance learning system of the Department of Defence as authoritative power source. The main function of dialogue in the system is to vest the interest of this organization as programme directors and instructors are not fully emancipated. Students and instructors find it difficult to engage constructively academically. Learner-to-learner interaction and freedom of academic discourse is hampered as the result of authoritarian and prescriptive doctrine of a structured curriculum. It is then concluded that student support in the South African National Defence Force (SANDF) distance education settings does not address requirements of dialogue. / Thesis (PhD)--University of Pretoria, 2011. / Science, Mathematics and Technology Education / unrestricted

No description available.

Cette thèse propose différentes méthodes théoriques et numériques pour simuler à coût réduit le comportement des plasmas ou des faisceaux de particules chargées sous l’action d’un champ magnétique fort. Outre le champ magnétique externe, chaque particule est soumise à champ électromagnétique créé par les particules elles-mêmes. Dans les modèles cinétiques, les particules sont représentées par une fonction de distribution f(x,v,t) qui vérifie l’équation de Vlasov. Afin de déterminer le champ électromagnétique, cette équation est couplée aux équations de Maxwell ou de Poisson. L’aspect champ magnétique fort est alors pris en compte par un dimensionnement adéquat qui fait apparaître un paramètre de perturbation singulière 1/ε. / This thesis is devoted to the study of charged particle beams under the action of strong magnetic fields. In addition to the external magnetic field, each particle is submitted to an electromagnetic field created by the particles themselves. In kinetic models, the particles are represented by a distribution function f(x,v,t) solution of the Vlasov equation. To determine the electromagnetic field, this equation is coupled with the Maxwell equations or with the Poisson equation. The strong magnetic field assumption is translated by a scaling wich introduces a singular perturbation parameter 1/ε.

Title from PDF of title page. / Document formatted into pages; contains 215 pages. / Originally submitted in HTML and can be accessed at http://www.lib.usf.edu/ETD-db/theses/available/etd-04102002-122814/unrestricted/default.htm / Thesis (Ph.D.)--University of South Florida, 2002. / Includes bibliographical references. / Text (Electronic thesis) in PDF format. / ABSTRACT: Electronic theses and dissertations (ETDs) are an evolving genre of graduate student research that is gaining widespread acceptance among universities in the international community. ETDs are also beginning to diffuse slowly among American universities; however, a number of issues continue to work against more rapid adoption among intitutions in the United States. / ABSTRACT: This dissertation examines ETDs as an evolving electronic research genre by (1) historicizing the situated development of its predecessor, the traditional print dissertation, in nineteenth century German and American Universities; (2) reporting on the current state of the Networked Digital Library of Electronic Theses and Dissertations, an initiative of Virginia Polytechnic University; (3) analyzing ETDs as a technological innovation undergoing the diffusion process according to Emmet Roger's Diffusion of Innovation Theory; and (4) presenting the results of an ETD pilot project case study carried out at the University of South Florida. / System requirements: World Wide Web browser and PDF reader. / Mode of access: World Wide Web.

Treasure is a feature-length narrative fictional film directed by Chris Williamson as part of the requirements for earning a Master of Fine Arts in Entrepreneurial Digital Cinema from the School of Visual Arts and Design at the University of Central Florida. This thesis is a documentary record of the film production from concept to completion. In this thesis the concerns of authorship are explored from the perspective of the author as the executive producer, writer, and director of the film.

Cette thèse propose différentes méthodes théoriques et numériques pour simuler à coût réduit le comportement des plasmas ou des faisceaux de particules chargées sous l'action d'un champ magnétique fort. Outre le champ magnétique externe, chaque particule est soumise à un champ électromagnétique créé par les particules elles-mêmes. Dans les modèles cinétiques, les particules sont représentées par une fonction de distribution f(x,v,t) qui vérifie l'équation de Vlasov. Afin de déterminer le champ électromagnétique, cette équation est couplée aux équations de Maxwell ou de Poisson. L'aspect champ magnétique fort est alors pris en compte par un adimensionnement adéquat qui fait apparaître un paramètre de perturbation singulière 1/ε. Le premier chapitre de cette thèse est une introduction à la fusion contrôlée par confinement magnétique dans les Tokamaks. Le second chapitre est consacré à la théorie gyrocinétique géométrique. Cette théorie repose sur la géométrie différentielle et la dynamique des systèmes hamiltoniens. L'objectif est de faire une succession de changements de coordonnées afin de se ramener à un système proche du centre-guide historique dans lequel les expressions de la matrice de Poisson et du Hamiltonien permettent une réduction de la dimension des trajectoires. Le chapitre 3 met en pratique les mêmes techniques sur un autre problème, la modélisation paraxiale d'un faisceau de particules chargées. Le dernier chapitre est dédié à un schéma numérique basé sur un intégrateur exponentiel en vitesse. Ce schéma a pour objectif d'approcher numériquement des solutions fortement oscillantes avec une méthode Particle-In-Cell en utilisant un pas de temps beaucoup plus grand que la période d'oscillation rapide. Il est testé sur une équation de Vlasov linéaire ainsi que sur le système de Vlasov-Poisson.