Orientador: Francisco Maugeri Filho / Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia de Alimentos / Made available in DSpace on 2018-08-14T20:03:20Z (GMT). No. of bitstreams: 1 Mondragon-Bernal_OlgaLucia_D.pdf: 3071124 bytes, checksum: 5b74f16ca67880acdcfbbd92df382fb9 (MD5) Previous issue date: 2009 / Resumo: É reportado que problemas como a disbiose intestinal, que consiste no desequilíbrio da flora intestinal causada por diversos fatores da vida moderna, aumentaram bruscamente nos últimos anos. Há, portanto uma tendência mundial em reconhecer o problema de disbiose intestinal e a busca por parte dos consumidores conscientes de dietas saudáveis que melhorem tal equilíbrio. O extrato hidrossolúvel de soja é uma matéria-prima com grande potencial para o desenvolvimento de alimentos com apelo saudável como bebidas fermentadas funcionais simbióticas (probióticos e prebióticos). No Laboratório de Engenharia de Bioprocessos da Faculdade de Engenharia de Alimentos da UNICAMP desenvolveu-se, em 2004, um alimento à base de extrato hidrossolúvel de soja contendo bifidobactérias, lactobacilos e prebióticos em simbiose. Mostrou-se que o extrato de soja é um meio adequado para cultivo de probióticos resultando em alta concentração de células (>10 logUFC/mL) e de oligossacarídeos no produto final. Porém, apesar do alimento simbiótico ter apresentado boas características funcionais, este não seria bem aceito pelo consumidor, já que suas características sensoriais foram insatisfatórias. Durante a vida de prateleira foi observado que o produto apresentava também sinérese e outras mudanças pela alta atividade microbiana. Devido aos problemas apresentados, este novo estudo visou a otimização sensorial do alimento simbiótico a base de extrato hidrossolúvel de soja, além da análise das mudanças ocorridas durante a vida-deprateleira, dos efeitos de diversas variáveis na estabilidade do produto e finalmente a avaliação dos efeitos probióticos através da resistência às condições simuladas do trato gastrointestinal. Assim sendo, foram obtidos protótipos de alimentos simbióticos fermentados a base de soja, adoçados com sacarose ou na versão diet em sacarose. Estes produtos apresentaram melhora no sabor e doçura com aceitação e intenção de compra pelo público alvo. Produtos com alto teor de extrato de soja (>8% m/v), frutooligossacarídeos (>2% m/v) e/ou polidextrose (> 2% m/v) adoçados com sacarose (12% m/v), ou com associação dos edulcorantes hipocalóricos acessulfame-k e sucralose em proporção 25:75 m/m (0,024% m/v), fermentados por quatro bactérias lácticas probióticas L. acidophilus LAC4, L. paracasei subsp paracasei LBC81, L. rhamnosus LR32 and B. longum BL04 (em proporção 15:15:10:60 respectivamente), e, sem adição do agente tamponante lactato de cálcio, apresentaram boas características de estabilidade durante 30 dias de vida-deprateleria e com características funcionais de resistência às condições gastrointestinais simuladas do trato digestivo humano. Os produtos desenvolvidos neste projeto inexistem no mercado brasileiro e viriam suprir a lacuna existente de alimentos apropriados para pessoas que sofrem de disbiose intestinal e outras disfunções relacionadas com o consumo de leite de bovino e derivados / Abstract: Problems as intestinal dysbiosis, that is imbalances in intestinal flora caused by many aspects of modern life, have been growing largely in recent years. There is a worldwide trend in recognizing intestinal dysbiosis as a disease and the conscientious consumers of the importance of healthful diets have been searching for foods that improve this balance. The hydrosoluble soy extract is a raw material with great potential in the food development with a healthy appeal as the synbiotics functional and fermented drinks (with probiotics and prebiotics substances. In the Bioprocess Engineering Laboratory of the Food Engineering College at UNICAMP it was developed, in 2004, a foodstuff from hydrosoluble soy extract, containing Bifidobacterium, Lactobacilli strains and prebiotic in synbiosis. It was shown that the soy extract is a good broth for probiotics culture resulting in high counting (> 10 logUFC/mL) in the final product and of oligosaccharides. However, although that the synbiotic food presented good functional characteristics, this would not be well accepted for the consumer, due to its sensorial characteristics were unsatisfactory. During the shelf life it was observed that the product also presented syneresis and other changes caused by the high bacteria activity. For the mentioned problems the goals of this new study were the sensorial optimization of the synbiotic food from soymilk, analysis of the changes during shelf life, effects of many variables in the product stability and finally the determination of probiotic effects by the resistance to simulated conditions of gastrointestinal tract. Thus food prototypes of fermented synbiotic foods from soymilk were prepared, sweetened with sucrose or in the version diet in sucrose. These products presented improvement in the flavor and sweetness with acceptance and purchasing intent for the target consumers. Products with high concentration of soymilk (> 8% m/v), fructooligosaccharides (> 2% m/v) and/or polidextrose (> 2% m/v) sweetened with sucrose (12% m/v), or with mixture of the hipocaloric sweeteners acesulfame-k and sucralose in the ratio 25:75 m/m (0.024% m/v), fermented by four probiotic bacteria L. acidophilus LAC4, L. paracasei subsp paracasei LBC81, L. rhamnosus LR32 and B. longum BL04 (in ratio 15:15:10:60 respectively), and, without addition of the calcium lactate buffer agent, presented good characteristics of stability during 30 days of shelf life and good functional resistance to the simulated gastrointestinal conditions of the human digestive tract. The developed products in this work do not exist in the Brazilian market and would come to supply options of adequate food for people with intestinal dysbiosis and disorders or dysfunctions related to bovine milk and derivatives consumption / Doutorado / Doutor em Engenharia de Alimentos

Background Clinical usable assessment methods to quantify mobility, balance, stability and postural control functions together in a full kinetic chain movement are sparse. Normative data of such dynamic functions in different group of athletes are  still lacking and therefore the relationship between dynamic functional mobility and overuse injuries are also unknown. The prevalence of overuse injuries among adolescent athletes are continuously high and team gymnastic is one example of a sport with multiple and underestimated overuse injuries.   Aim The first aim of study was to establish normative data of dynamic functional mobility in a group of elite team gymnasts. The second aim was to investigate ongoing overuse injuries and evaluate associations between ongoing overuse injuries and dynamic functional mobility in the group.   Method A descriptive cross sectional study including 31 female elite team gymnasts 16-19 years old were conducted. “The hand reach star excursion balance test” (HSEBT) was used to measure dynamic functional mobility in 20 different movement patterns. The "Oslo Sports Trauma Research Center Overuse Injury Questionnaire"(OSTRC) was used to record and analyse severity of ongoing overuse injuries in the group. Pearson correlation analysis was used to determine the relationship between the scoring in the HSEBT- tests and scoring on the OSTRC.   Results A majority of the participants presented with scores near the maximum values on the HSEBT. Further,  97% of the subjects had an ongoing overuse injury. Severe injuries, affecting participation in sport were present in 67%. Correlations was found between prevalence of severe injury in the lower back and lower scoring on the right leg in a rotational movement pattern (r= -0,42) whereas prevalence of severe injury in the hip was associated with extreme high mobility in a sidebending pattern in both legs (r= 0,50, 0,49). There was also a relationship between individuals with multiple severe overuse injuries and dynamic functional mobility in an extended movement pattern of the left leg (r= -0,36, -0,38).   Conclusion Normative data of dynamic functional mobility according to the HSEBT can provide clinicians with reference points to compare elite female team gymnasts. There was an indication of association between limited mobility in some of the included tests and prevalence of overuse injuries in the lower back and hip. This study included a small sample and therefore conclusions have to be interpreted carefully.

Dėl didėjančio integrinių schemų sudėtingumo ir darbinių dažnių vėlinimo gedimų nustatymas tampa svarbia schemų kūrimo dalimi. Programiniai schemų prototipai leidžia atlikti schemų testavimą ankstyvojoje stadijoje. Šiame darbe yra pateikiama vėlinimo gedimų nustatymo metodų analizė ir jų palyginimas. Tyrimo objektu pasirinktas perėjimo gedimų modelis. Dokumente aprašomas AntiRandom metodo pritaikymo galimybės funkcinių testų generavimui. Taip pat yra trumpai apžvelgiami egzistuojantys sprendimai rinkoje. Projektavimo skyriuje yra aprašoma suprojektuota ir realizuota sistema, kuri susideda iš dviejų posistemių: funkcinių testų generatoriaus bei rezultatų kaupimo ir analizės posistemės. Funkcinių testų generatoriuje realizuoti du atsitiktinio ir AntiRandom metodai. Paskutinėje dokumento dalyje yra pateiktas atliktas eksperimentinis tyrimas su realizuota sistema. Taip pat yra pateikiami eksperimentinio tyrimo metu pasiekti rezultatai bei padarytos viso darbo išvados. / The increasing complexity of integrated circuits and operating frequency led delay fault identification to become an important part of the schemes development. Software prototypes allow to start testing phase at an early stage. This work covers the delay fault detection method analysis and comparison. For the study is selected transition fault identification. The paper describes the AntiRandom method and customization possibilities for the functional test generation. There is also a brief overview of an existing solutions on the market. The design section describes the designed and implemented system which consists of two subsystems: functional tests generator and results storage and analysis subsystem. Functional test generator has two random methods and customized AntiRandom method. The last part of the document covers an experimental study for the created system. It consists of results of the experiments and conclusions of the whole work.

Introduction: Functional testing which is used in rehabilitation is mainly based on aspection and palpation. It is a subjective examination of a patient and you cannot find out specific physical quantities with this method. If you want to use functional tests in clinical practise it is necessary to determine the reliability of the tests. Aim: To determine the inter-rater reliability for the DNS tests and to create a detailed descriptive statistics and a new evaluation sheet. Materials and methods: There were six experienced evaluators who are trained for the DNS method. We have worked with a mixed group of patients. There were patients with health problems as well as patients without any difficulties (n = 10 women, average age - 34, 5, n = 4 men, average age - 35, 2). We used percentage agreement, Fleiss's kappa coefficients (κ) and P-value. Results: The research of DNS tests reliability is innovative. Evaluators of DNS tests usually agree with each other. In some cases there is a problem with using Fleiss's kappa coefficients (κ) because of the position of relative frequencies. In most tests we found out that the inter-rater reliability is good (κ ≥ 0.80), substantial (0.60 ≤ κ < 0.80) and moderate (0.40 ≤ κ < 0.60). Conclusion: The evaluation of one character in a case of one patient by three...

O objetivo da presente dissertação foi avaliar e comparar o comportamento da movimentação do joelho, nos testes Drop Vertical Jump (Drop), Single Hop (Hop), Triple Hop (Triplo), Cross-over Hop (Cross), Six-Meter Timed Hop (6M) e Sidestep Cutting (Sid), através de análises cinemáticas das rotações e velocidades angulares do joelho, e pela co-ativação muscular do membro inferior, em jogadoras de handebol. O desenho experimental da pesquisa foi um estudo transversal, na qual foram avaliadas 12 participantes (idade média de 21,2±2,4 anos, massa corporal média de 68,9±10,3kg e estatura média de 1,70±0,04m). Antes das avaliações, todas foram demarcadas com 25 marcadores retrorefletivos em proeminências ósseas de interesse. Além disso, foram acoplados 10 sensores de eletromiografia (EMG) (EMG TrignoTM Wireless System), nas musculaturas do reto femoral, bíceps femoral e glúteo médio. Após foram aplicados os seis testes funcionais, em três tentativas válidas com o membro dominante. Os dados da cinemática foram obtidos pelo sistema de captura de movimento VICON (Centennial, CO, EUA) e analisados por rotinas desenvolvidas no software MatLab (Mathworks Inc., Natick, MA, USA). Os ângulos de rotação do joelho, especificamente o valgo do joelho, foram obtidos pelos Ângulos de Euler. Já as velocidades angulares escalares foram geradas pelo quatérnion unitário. E por último, as razões de co-ativação entre o reto femoral/bíceps femoral (RB) e reto femoral/glúteo médio (RG) foram através do sinal da integral normalizada da EMG. A partir disso, foram traçados os momentos das variáveis em cada teste avaliado. Para os ângulos de valgo foram extraídos os valores no contato inicial (CI), 40 e 100 ms após o CI, na flexão máxima (Flexmax) e no valgo máximo do joelho (Valgomax). Para as velocidades angulares foram os mesmos instantes, mais o momento de velocidade positiva (Velpos) e velocidade negativa (Velneg). Para as co-ativações foram os mesmos instantes dos ângulos, mais o momento da força pico de reação do solo (FPRS), por duas plataformas de força (Columbus, EUA). Nos ângulos de valgo houve interação [F(2,220)=11,456; p<0,001] na comparação (momento x testes) revelando diferenças significativas nas comparações pareadas. No CI, no 100ms e na Flexmax o Sid apresentou diferença para quase todos os outros testes, assim como o Drop na Flexmax. Nas velocidades angulares houve interação [F(30,330)=14,476; p<0,001] com diferenças significativas nas comparações pareadas. Nos instantes de 40ms, 100ms, Velpos e Velneg o Drop apresentou diferença para quase todos os testes, assim como o 6M apontou diferença para todos os outros testes no 100ms e Velneg. Houve ainda relação moderada: do Cross no momento de Valgomax nas variáveis ângulo de valgo e a velocidade angular (p=0,032); do Sid no momento 40ms nas variáveis do ângulo de valgo e a coativação RB (p=0,015); e no Hop no momento 100ms nas variáveis de ângulo de valgo e a coativação RG (p=0,029). Contudo, pode-se concluir que os testes funcionais de instabilidade dinâmica do joelho para as variáveis cinemáticas apresentam comportamentos específicos. Além disso, ficou demonstrado que o aumento do valgo do joelho no Cross é influenciado pela rapidez da velocidade angular. Podemos concluir ainda, que a adaptação neuromuscular RB, no Sid - 40ms, sofre a influência direta do ângulo de valgo, e que o sinergismo de RG, no Hop - 100ms, é fundamental para o controle do ângulo de valgo do joelho / The objective of this thesis was evaluate and compare the knee movement behavior, in the tests Drop Vertical Jump (Drop), Single Hop Test (Hop), Triple Hop Test (Triple), Cross-over Hop Test (Cross), Six-Meter Timed Hop Test (6M) e Sidestep Cutting (Sid), through rotation and knee angular speed kinematic analysis, and by the low member muscles co-activation, in female handball players. The experimental research design was a cross-sectional in which were evaluate 12 participants in the average age of 21.2±2.4, average body mass of 68.9±10.3kg and average height of 1.70±0.04m. Before the evaluation all made a 5 minutes warm-up and marked with 25 reflective markers in bony prominences of interest for further kinematic analysis. Besides that, where attached 10 electromyography sensors (EMG TrignoTM Wireless System), recto-femoral muscles, femoral biceps and gluteus medium. After the volunteer preparation where evaluated the six functional tests Drop, Hop, Triple, Cross, 6M and Sidestep Cutting in three valid attempts with the dominant limb. The kinematic data where obtained by the movement capture system VICON (Centennial, CO, EUA) and analyzed by the developed routines using the software MatLab (Mathworks Inc., Natick, MA, USA). The knee rotation angle, specifically the knee valgus, where generated by the sequences of Euler rotation angle. The scalar angular speeds where drawn by unitary quaternion. Finally, the co-activation ratios between the recto-femoral/femoral biceps (RB) and recto-femoral/gluteus medium (RG) where normalized integral sign by EMG. From this where set the variables moments in each evaluated test. To the valgus angle where extracted the initial contact values (CI) through a force platform (Columbus, EUA), 40ms and 100ms after the CI, in maximum flexion (Flexmax) and maximum knee valgus (Valgomax). To angular speeds where the same moments plus the positive speed momentum (Velpos) and negative speed momentum (Velneg). To the co-activation where used the same angle moments plus the moment of force peak ground reaction (FPRS). In the valgus angle there was interaction [F(2,220)=11,456; p<0,001] comparing (moment x tests) revealing significant differences in pairwise comparison. In CI, on 100ms and Flexmax the Sid presented difference to all most all the other tests likewise the Drop on Flexmax. In the angular speed there was the interaction [F(30,330)=14,476; p<0,001] with significant differences in pairwise comparison. In the moment 40ms, 100ms, Velpos and Velneg the Drop presented differences to all most all the other tests likewise the 6M pointed differences to all the other 100ms and Velneg tests. There was also a moderated relation from: Cross in the Valgomax moment in valgus angle variables and angle speed (p=0,032); Sid in 40ms moment the valgus angle variables and the co-activation (p=0,015); Hop in 100ms moment the valgus angles variables and co-activation RG (p=0,029). We can conclude that the knee dynamics instability functional tests in the dynamic valgus critical moments analysis, show that the valgus angle variables and angular velocity specific behaviors in the tests applied. Besides that was established that the knee valgus increase in Cross is influenced by the speed of angular velocity. Also can be concluded that the neuromuscular adaptation RB in SID - 40ms, has a direct influence of valgus angle and the synergism of Hop - 100ms, is fundamental to the knee valgus angle control

O valgo dinâmico de joelho é amplamente relacionado à disfunção e ao mau alinhamento postural e membros inferiores. No entanto, não está estabelecido como o valgo dinâmico de joelho está associado às adaptações cinemáticas de tornozelo e pé e ao comportamento das cargas plantares durante atividades funcionais. Objetivo: Comparar a amplitude articular de dorsiflexão do tornozelo, adução e abdução de retropé, pronação e supinação de subtalar, bem como avaliar a área e a pressão plantar total e do mediopé em diferentes tarefas funcionais utilizadas na avaliação do valgo dinâmico de joelho em indivíduos clinicamente saudáveis de ambos os sexos a partir da avaliação cinemática e baropodométrica. O objetivo foi correlacionar o valor do pico de valgo dinâmico de joelho com as amplitudes de tornozelo, com a área e pressão plantar do pé nestas tarefas. Materiais e métodos: Foram incluídos 30 voluntários sem histórico de lesão ou trauma nos membros inferiores, sendo 15 homens e 15 mulheres. Os voluntários tiveram o membro inferior dominante avaliado na realização de cinco diferentes tarefas funcionais: descida de degrau, single leg step down, agachamento unipodálico, aterrissagem unipodálica e drop vertical jump. Para a avaliação cinemática foi utilizado o sistema Vicon (Centennial, CO, EUA) com um total de 34 marcadores refletivos bilateralmente, para observação das variáveis cinemáticas tridimensionais de joelho, tornozelo e pé. A área e a pressão plantar foram obtidas do Baropodômetro Matscan System (Tekscan®. South Boston, MA, EUA). Para as análises dos dados cinemáticos e baropodométricos foram considerados o momento do pico de valgo de joelho nas diferentes tarefas funcionais realizadas. Resultados: As amplitudes de dorsiflexão de tornozelo (P = 0,489), adução e abdução do retropé (P = 0,0791), pronação e supinação de retropé (P = 0,163) e pronação e supinação da articulação subtalar (P = 0,305) não foram diferentes entre nenhuma das tarefas realizadas. Quanto as variáveis de área e pressão plantar total do pé, as tarefas de agachamento unipodálico e a descida de degrau apresentaram os maiores valores em comparação as tarefas de aterrissagem unipodálica (p = 0,005 e 0,027; ES = 0,66), drop vertical jump (p = 0,001 e p = 0,001; ES = 0,38) e single leg step down (p = 0,01 e p = 0,007; ES = 0,43). Os menores valores foram observados na tarefa de drop vertical jump com diferenças observadas para todas as tarefas (p<0,05). Já para as variáveis de pressão plantar do mediopé, a maior pressão foi observada na tarefa de descida de degrau que foi diferente de todas as tarefas (p<0,005), exceto a tarefa de agachamento unipodálico (p=0,13 es= 0,306) e as menores pressões foram encontradas na tarefa do drop vertical jump que apresentou diferenças para a tarefa de agachamento unipodálico (p=0,028 es= 0,485), aterrissagem unipodálica (p=0,006 es= 0,687) e descida de degrau (p=0,001 es= 0,257), porém não apresentou diferenças quando comparada a tarefa de single leg step down (p=0,374 es= 0,170). As variáveis de pico de valgo dinâmico de joelho apresentaram baixa correlação com as variáveis de pronação da articulação subtalar, área e pressão total e do mediopé. Conclusão: As tarefas funcionais avaliadas não apresentam diferença na cinemática de tornozelo e pé. A tarefa de descida de degrau levou a uma maior área de contato e maior pressão plantar do pé e a tarefa de drop vertical jump apresentou menor área de contato e menor pressão plantar do pé. Não houve correlação do pico de valgo dinâmico de joelho, com as amplitudes de tornozelo e pé, bem como a área e a pressão plantar do pé. / Dynamic knee valgus is largely related to the dysfunction and poor postural alignment of this articulation. However, isn\'t established how dynamic knee valgus can be associated with ankle and foot kinematic adaptations and the behavior of the plantar loads during functional activities. Objective: To compare the joint amplitude of ankle dorsiflexion, adduction and abduction of rearfoot, pronation and supination of midfoot, as well as to evaluate the total and midfoot area and pressure in different functional tasks used in the evaluation of dynamic knee valgus in clinically healthy individuals of both sexes from the kinematic and baropodometric evaluation. Besides that, the goal was to correlate the value of the dynamic knee valgus peak with the ankle amplitudes, with the foot area and foot pressure in these tasks. Materials and methods: It included 30 volunteers with no history of injury or trauma in the lower limbs, 15 men and 15 women. The volunteers had the dominant lower limb evaluated in performing five different functional tasks: step descent, single leg step down, single leg squat, unipodal landing and drop vertical jump. For the kinematic evaluation, the Vicon system (Centennial, CO, USA) with a total of 34 markers were used bilaterally to observe the three-dimensional knee, ankle and foot kinematics variables. The area and plantar pressure were obtained from the Matscan System Baropodometer (Tekscan®, South Boston, MA, USA). For the analysis of the kinematic and baropodometric data, the moment of the knee valgus peak was considered in the different functional tasks performed. Results: Results: The amplitudes of ankle dorsiflexion (P = 0.489), adduction and abduction of the rearfoot (P = 0.0791), pronation and supination of the rearfoot (P = 0.163) and pronation and supination of the subtalar joint (P = 0.305) did not Were different between any of the tasks performed. Regarding the variables of area and total foot pressure of the foot, the tasks of unipodal squatting and stair descent presented the highest values in comparison to the tasks of unipodal landing (p = 0.005 and 0.027; ES = 0.66), drop vertical jump (P = 0.001 and p = 0.001, ES = 0.38) and single leg step down (p = 0.01 and p = 0.007, ES = 0.43). The lowest values were observed in the drop vertical jump task with differences observed for all tasks (p <0.05). For the midfoot plantar pressure variables, the greatest pressure was observed in the task of stair descent that was different from all tasks (p <0.005), except for the one-legged squat task (p = 0.13 and 0.306) (P = 0.028 es = 0,485), unipodal landing (p = 0,006 es = 0,687), and lowering of the step (p = 0.001 es = 0.257), but did not present differences when compared to single leg step down task (p = 0.344 es = 0.170). The variables of dynamic knee dynamic valgus presented a low correlation with the variables of pronation of the subtalar joint, area and total pressure and midfoot.Conclusion: The functional tasks evaluated don\'t present differences in ankle and foot kinematics. The task of step descent led to a greater area of contact and greater plantar pressure and the task of drop vertical jump had a lower area of contact and lower foot pressure of the foot. There was not a correlation of the dynamic knee valgus peak with the ankle and foot amplitudes, as well as foot area and pressure.

Um dos fatores que podem contribuir para as lesões na articulação do joelho é a incapacidade do indivíduo em manter durante atividades funcionais, um bom alinhamento entre os segmentos corporais tais como tronco, quadril e joelho. Na maioria das vezes o aumento do valgo dinâmico de joelho é apontado como um fator etiológico de lesões nessa articulação e sua identificação precoceé importante, bem como de outros fatores biomecânicos. Os testes funcionais para avaliação do valgo são importantes ferramentas para analisar o alinhamento dinâmico entre os segmentos corporais, porém ainda não há na literatura subsídios cinesiológicos que comparem a amplitude articular do joelho, quadril e tronco nas principais tarefas funcionais e utilizadas na prática clínica. Da mesma forma, a relação da cinemática desses segmentos com o torque dos músculos estabilizadores do quadril e joelho ainda é controverso. Objetivos: Comparar os valores angulares dados pela cinemática de tronco, quadril e joelho em cinco diferentes tarefas funcionais utilizadas para avaliação do valgo dinâmicoe correlacionar com o pico de torque de joelho e quadril. Materiais e Métodos: 30 voluntários saudáveis sem historia de dor ou disfunção em membros inferiores, de ambos os sexos (15 homens e 15 mulheres) com idade de 18 a 35 anos realizaram os testes de força muscular isométrica para todos os grupos musculares de joelho e quadril utilizando o Dinamômetro isocinéticoBiodex®. Entre 3 a 7 dias após o teste de força muscular foi realizada a análise cinemática de tronco, quadril e joelho utilizando o Sistema VICON (Centennial, CO, EUA) durante a realização de cinco diferentes tarefas funcionais para avaliação do valgo dinâmico de joelho, sendo elas: descida de degrau, singlelegstepdown, agachamento unipodal, aterrissagem unipodal, drop vertical jump. Resultados: A tarefa dedrop vertical jump apresentou os maiores valores de pico de valgo(média: 20,1º p<=0,04), rotação interna de joelho(média: 9,7º p<=0,003), flexão de quadril(média: 38,8º p<=0,001) e menores valores de rotação de tronco (média: 0,07º p<=0,009). A tarefa de single legstepdown apresentou maiores valores de flexão de tronco (média: 10,2º p<=0,002) em relação às outras tarefas funcionais. Foi observada uma correlação negativa e fraca do pico de torque de rotadores externos de quadril e inclinação ipsilateral de tronco(R= - 0,36; p=0,049) na tarefa de descida de degrau. Não houve evidências de correlação entre o pico de torque de abdutores, adutores, rotadores internos,rotadores externos, flexores, extensores de quadril e flexores e extensores de joelho com a cinemática de joelho, quadril e tronco nas tarefas funcionais de agachamento unipodal, aterrissagem unipodal, drop vertical jump e singlelegstepdown. Conclusão:A compreensão das variáveis cinesiológicas de joelho, quadril e troncoé fundamental para direcionar o clínico na escolha do teste funcional para avaliação do valgo dinâmico.Todas as tarefas analisadas são efetivas para avaliar o valgo dinâmico, porém adrop vertical jumpparece demandar mais estratégias de joelho e quadril, e a tarefasingle legstepdown apresentou maiores alterações cinesiológicasde tronco. Além disso, o pico de torque de quadril e joelho não exerceu influência no desempenho dos testes em indivíduos saudáveis / One of the factors that can contribute to injuries in the knee joint is the individual\'s inability to maintain an alignment between the body segments such as trunk, hip and knee during functional activities. Most of the time the dynamic knee valgus has been suggested as an etiologic factor that contributefor this joint injuries and early identification along with biomechanical factors associated with knee joint injuries is important. The functional tests for knee valgus evaluation are important tools for assessing the dynamic alignment between body segments, but there is no kinesiological subsidies in the literature that compare knee, hip and trunk in most of the described functional tasks used in the clinical practice and their relationship with the hip and knee strengthin healthy subjects. This study aimsto compare the angle values by the trunk, hip and knee kinematics in five different functional tasks used to evaluate the dynamic valgus and correlate this with the muscle\'s torque of the hip and knee. A sample of 30 healthy volunteers (15 men and 15 women) aged 18 to 35, with no history of pain or dysfunction in the lower limbs, performed a isometric muscle strength tests for all theknee and hip groups muscles using an isokinetic dynamometer Biodex®. Between 3 and 7 days after the muscle strength testing trunk, hip and knee kinematic analysis was performedduring five different functional tasks for evaluating the dynamic knee valgus using the Vicon system (Centennial, CO, USA).The functional tests were: stair descent, single-leg step down, single leg squat, single leg landing, drop vertical jump. ANOVA repeated measures was used to verify the differencesin the tasks for knee, hip and trunk kinematics and Pearson\'s correlation was used to verify correlations between hip and knee muscle\'s torque and knee, hip and trunk kinematics. The drop vertical jump task showed the highest peak values of valgus (average: 20.1º p<=0,04), internal rotation of the knee (average: 9,7º p<=0,003), hip flexion (mean: 38,8º p<=0,001) and lower trunk rotation values (mean 0,07º p<=0,009). The single leg step down task showed greater trunk flexion values (mean: 10,2º p<=0,002) in relation to all functional tasks. It was observed a negative and weak correlation of thehip external rotators torque and ipsilateral trunk lean (R = - 0.36, p = 0.049) in stair descent task. There was no evidence of correlation between peak torque of the hip abductors, adductors, internal rotators, external rotators, flexors and extensors and flexors, extensors of the knee with knee, hip and trunk kinematics in the single leg squat, landing, drop vertical jump and single-leg step down. For choosing a functional task to evaluate the dynamic valgus is crucial to the clinicians understand the kinesiological variables of knee, hip and trunk. All assessed tasks are effective to evaluate the dynamic knee valgus, although the drop vertical jump task requires more adjustments in the knee and hip, and the single leg step down task has higher kinesiological changes in the trunk.In addition, knee and hip peak of torque had no influence on the performance of the tests in healthy individuals

Magistro darbe analizuojamas funkcinio testo sudarymas aukštame abstrakcijos lygmenyje. Toks testo kūrimo būdas leidžia vystyti testą ankstyvuose projektavimo etapuose lygiagrečiai su kitomis projektavimo proceso veiklomis. Realizuojamas funkcinis vėlinimo testo sudarymo algoritmas pagal pokyčius išėjimuose, kuris remiasi tik programinio prototipo pirminių įėjimų ir pirminių išėjimų reikšmėmis. Atliekami eksperimentai. Eksperimento metu atliekami testinių rinkinių generavimai 35 loginėms schemoms pasinaudojant 15 skirtingos spartos procesorių. Gauti testo greitaveikos bei kokybės rezultatai parodė jog algoritmas pakankamai spartus ir gebantis rasti visus reikalingus rinkinius funkcinio vėlinimo testo sudarymui. / This work studies the test generation in functional level of the circuits. Such an approach allows developing the test at the early stages of the design process in parallel with other activities of this process. Created test generation algorithm of the functional test that is based solely on the primary input values and the primary output values of the programming prototype. The experiment contains 35 logic schemas processed test generation algorithm on 15 different powers CPU. The results of experiment shows that suggested algorithm is capable to find all needed pairs to complete functional test and the speed of algorithm is measurable at the same time.

Rupture of the anterior cruciate ligament (ACL) increases anterior-posterior (AP) laxity. The treatment aims to reduce or teach the patient to control this instability. Altered kinematics due to absent ligament function may result in knee arthrosis. This study evaluated the clinical and functional results of reconstructive surgery. Roentgen stereophotogrammetry (RSA) was used to analyse the stabilising effect of knee braces, reconstructive surgery and the kinematics of the knee with and without weight-bearing. The stability of the knees were assessed in 86 patients with ACL injuries before and/or after reconstructive surgery with the RSA technique and with the KT-1000 arthrometer The KT- 1000 (89 N) recorded smaller side to side differences than the RSA set-up without any correlation between the methods. The effect of three different braces on the AP and rotatory laxity was studied on patients with ACL injuries. The ECKO and the modified Lenox Hill reduced the instability with about one third. The SKB had no significant effect. None of the braces decreased the internal rotatory laxity but the Lenox Hill reduced the external rotatory laxity. Thirty-two patients with old ACL tears were treated with surgical reconstruction using the over the top technique (OTT) with or without augmentation. A small reduction in AP laxity was observed at the 6 month follow-up, The AP laxity was almost the same two years after as before surgery. No correlation was observed between the stability and knee function. Fifty-four patients with old unilateral anterior cruciate ligament injuries were randomised either to the over the top (OTT) or the isometric femoral tunnel position (ISO) at ACL reconstructive surgery. Seven of 24 (ISO) and 9 of 25 (OTT) had "normal" laxity two years after surgery. The patients operated with the ISO technique did not have better subjective knee function, muscle strength, functional performance or knee stability than patients operated with the OTT technique. The knee kinematics in patients with chronic unilateral ACL ruptures were examined during active extension in the supine position (13 patients) and during extension and weight-bearing (13 patients). The tibia displaced at an average 1.9 mm more anteriorly and 0.8 mm distally in the injured than in the intact knees during active extension. During extension and weightbearing the tibia was about 2 mm more posteriorly positioned than in the intact knee. The ACL rupture did not affect tibial rotations. Conclusions: The RSA recorded larger side to side differences in ACL injured and reconstructed patients than the KT-1000 arthrometer. Some knee braces are able to reduce AP laxity in ACL injured knees. No correlation was observed after surgery between knee laxity and functional scoring or tests. ACL reconstructions with isometric graft position on the femoral side did not offer any advantages compared to the over the top placement. Altered knee kinematics in the ACL injured knees were observed during knee extension with and without weight-bearing. / <p>Diss. (sammanfattning) Umeå : Umeå universitet, 1993, härtill 6 uppsatser</p> / digitalisering@umu

Activity and fitness levels decline through the years from 30 to 60 years of age. Minimal research is available regarding functional assessment tools in this population. Reliable functional tools are needed to reintroduce individuals to appropriate physical activity levels following an injury and to maintain high levels of participation through their lifespan. The purposes of this study were multiple: 1) determine if three functional tests correspond with neuromotor fitness levels, 2) establish a model of functional tests, activity levels and descriptive data that distinguishes the most from the least fit, 3) describe expected mean functional test performances, and 4) demonstrate the reliability of the three functional tests in a sample of 30-60 year olds. 63 females and 38 males completed activity surveys, a neuromotor fitness test, the star excursion balance test (SEBT), the four square step test (FSST), and the Biering-Sorensen test of trunk extensor muscle endurance. Moderate to high reliability of the functional tests was determined with 29 subjects. The SEBT (r=.97), FSST (r=.88) and the Biering-Sorensen test (r=.64) were reliable. All functional tests were able to distinguish between the most fit and least fit with regards to the fitness tests. A model of the body mass index and the FSST predicted 25% of the variance in fitness level. Functional test means are reported by 10-year age groups and represent expected performance values.Health care professionals can use this information to compare their patients to this group of healthy individuals. This will allow them to have some idea of how well a person with an injury is performing relative to a healthy individual. Additionally the combination of a persons BMI plus their FSST gives the health care professional some information about an individual level of neuromuscular fitness so that the health care professional can guide their patients toward an appropriate level of physical activity after their injury or illness.