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Avaliação da ocorrência de rotavírus do grupo a após a implantação da vacina oral de rotavírus humano - VORH e análise comparativa das amostras circulantes antes e após a implantação da VORH em Goiânia – Goiás / Evaluation of group a rotavirus occurrence after human rotavirus oral vaccine implantation HROV and comparative analysis of circulating samples before and after HROV implantation in Goiânia - Goiás dataAlmeida , Tâmera Nunes Vieira 16 April 2011 (has links)
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Previous issue date: 2011-04-16 / Conselho Nacional de Pesquisa e Desenvolvimento Científico e Tecnológico - CNPq / The group A rotaviruses (RVA) are recognized as the main viral agents of acute childhood gastroenteritis, and due to the high morbidity-mortality rates vaccination has being considered the best alternative for prevention and control of RVA. In Brazil, in March, 2006 the Ministry of Health included the human rotavirus oral vaccine – VORH, which was developed from a monovalent attenuated strain G1P[8], in the National Immunization Program. In this context, the present study aimed at the investigation of the occurrence of RVA infections in the city of Goiânia after the implementation of the VORH, as well as the comparative analysis of the RVA circulating strains during the pre- and post-vaccination periods. For the RVA identification, 65 fecal samples obtained from children with acute gastroenteritis, in the period from 2008 to 2009, were tested by an immunoenzymatic assay and by polyacrilamide gel electrophoresis, with a total detection rate of 16.9% (11/65). After molecular characterization, the G2 genotype was identified in 10 samples, and four of those were considered as G2P[4] genotype. For the comparative analysis, the G2P[4] samples, as well as other 15 samples, obtained in the pre- and post-vaccination periods, were submitted to genomic sequencing of the coding regions for the proteins VP6, VP7 and NSP4. The molecular characterization of the VP7 gene showed that the G1 samples belonged to lineages I and II, sublineages d and b, respectively, and that all the G2 samples belonged to lineage II, with the differentiation of three sublineages, a, c and d, which were correlated with the collection periods. Regarding the VP6 genogroups and the NSP4 genotypes, a predominance of genogroup I and genotype A in postvaccination period was observed, whereas a predominance of genogroup II and genotype B was identified in the period before de vaccine implementation. The association between the G and P genotypes with VP6 genogroups and NSP4 genotypes revealed the predominance of the G1-P[8]-II-B combination in the pre-vaccination period, and the association G2-P[4]-I-A in the post-vaccination period, which suggests the substitution of these combinations after the implementation of the VORH. / Rotavírus do grupo A (RVA) são reconhecidos como os principais agentes virais da gastroenterite aguda infantil e, devido aos relevantes índices de morbi-mortalidade, a vacinação tem sido considerada a melhor alternativa para a prevenção e o controle de RVA. No Brasil, em março de 2006 o Ministério da Saúde adicionou ao Programa Nacional de Imunização a Vacina Oral de Rotavírus Humano (VORH), a qual foi desenvolvida a partir de uma amostra monovalente atenuada G1P[8]. Neste contexto, o presente estudo objetivou a investigação da ocorrência das infecções por RVA na cidade de Goiânia após a implantação da VORH, bem como proceder a uma análise comparativa das amostras de RVA circulantes nos períodos pré e pós-vacinal. Para identificação de RVA, 65 espécimes fecais coletados no
período de 2008 a 2009 de crianças com gastroenterite aguda, foram submetidos ao Ensaio Imunoenzimático e Eletroforese em Gel de Poliacrilamida, sendo observado um índice total de detecção de 16,9% (11/65). Após caracterização molecular, o genótipo G2 foi identificado em 10 amostras, sendo que quatro destas foram definidas como G2P[4]. Para análise comparativa, as amostras G2P[4], bem como outras 15 amostras coletadas nos períodos pré e pós-vacinal, foram submetidas ao sequenciamento genômico para as regiões codificantes das proteínas VP6, VP7 e NSP4. A caracterização molecular do gene de VP7 mostrou que as amostras G1 pertenciam às linhagens I e II, sublinhagens d e b, respectivamente, e que todas as amostras G2 pertencem à linhagem II, com a diferenciação de três sublinhagens, a, c e d, as quais foram correlacionadas com os períodos de coleta. Considerando os genogrupos de VP6 e genótipos de NSP4 identificados, observou-se predominância para genogrupo I e genótipo A no período pós-vacinal, enquanto, genogrupo II e genótipo B foram identificados com maior frequência antes da implantação da vacina. A associação entre os genótipos G e P com genogrupos de VP6 e genótipos de NSP4 revelou predominância da combinação G1-P[8]II-B no período pré-vacinal e da associação G2-P[4]-I-A no período pós-vacinal o que sugere uma substituição destas combinações após a implantação da VORH.
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Selective IgA Deficiency Mimicking Churg-Strauss Syndrome and Hypereosinophilic Syndrome: A Case ReportBAN, NOBUTARO, YAMAMURA, MASAHIRO, SATO, JUICHI, SUZUKI, TOMIO, HASHIMOTO, NAOZUMI, ANDO, TAKAFUMI, SATO, MOTOKI, TAKAMI, YUICHIRO, TAKEMOTO, AYUMU, FUKUTA, MAMIKO, KONDO, TAKESHI, TAKAHASHI, NORIYUKI 02 1900 (has links)
No description available.
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Genetic characterization of Canadian group A human rotavirus strains collected in multiple paediatric hospitals from 2007-2010McDermid, Andrew 28 August 2012 (has links)
Group A rotaviruses are a major cause of acute gastroenteritis in children. Almost all children are infected by the age of 5 years old. Rotavirus disease causes around 600,000 deaths per year. VP4 (P) and VP7 (G) genotypes were analyzed for prevalence and potential antigenicity, as they are known to elicit a neutralizing antibody response during infection. This study predicted the effectiveness of two recently licensed rotavirus vaccines based on Canadian surveillance.
271 out of 348 diarrhea samples from 8 paediatric hospital were successfully genotyped by PCR. Canadian rotavirus genotypes were found to be mostly G1P[8] followed by G3P[8], G2P[4], G9P[8], G4P[8], and G9P[4], between 2007 and 2010.
Reassortment and motif analysis was done with a subset of rotavirus-positive samples. There were no unusual reassortment events found in Canadian strains. Variations amongst strains were commonly genotype-specific, but otherwise rare. In conclusion, rotavirus vaccine escape is presently unlikely amongst Canadian strains.
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Genetic characterization of Canadian group A human rotavirus strains collected in multiple paediatric hospitals from 2007-2010McDermid, Andrew 28 August 2012 (has links)
Group A rotaviruses are a major cause of acute gastroenteritis in children. Almost all children are infected by the age of 5 years old. Rotavirus disease causes around 600,000 deaths per year. VP4 (P) and VP7 (G) genotypes were analyzed for prevalence and potential antigenicity, as they are known to elicit a neutralizing antibody response during infection. This study predicted the effectiveness of two recently licensed rotavirus vaccines based on Canadian surveillance.
271 out of 348 diarrhea samples from 8 paediatric hospital were successfully genotyped by PCR. Canadian rotavirus genotypes were found to be mostly G1P[8] followed by G3P[8], G2P[4], G9P[8], G4P[8], and G9P[4], between 2007 and 2010.
Reassortment and motif analysis was done with a subset of rotavirus-positive samples. There were no unusual reassortment events found in Canadian strains. Variations amongst strains were commonly genotype-specific, but otherwise rare. In conclusion, rotavirus vaccine escape is presently unlikely amongst Canadian strains.
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Epidemiology and control of gastrointestinal nematodes in first-season grazing cattle in Sweden /Dimander, Sten-Olof, January 2003 (has links) (PDF)
Diss. (sammanfattning) Uppsala : Sveriges lantbruksuniv., 2003. / Härtill 4 uppsatser.
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Self-care when suffering from gastroenteritis in Tanzania : Nurses perspective / Egenvård vid gastroenterit i Tanzania : Sjuksköterskors perspektivGärderup, Linnea, Karlsson, Ida January 2019 (has links)
According to World Health Organization 1.5 million people die every year due to diarrhoeal diseases. Diarrhoeal diseases may be caused by a multitude of different reasons, though WHO highlights the fact that 58% of these, are caused by lack of clean water, sanitation and hygiene. A qualitative study conducted with nurses working at different departments at a hospital in Tanzania. Semi-structured interviews were performed with ten nurses and the interviews were analysed through content analysis. The purpose was to describe nurses' experiences of working with self-care for patients suffering from gastroenteritis. Nurses experience that patients need more self-care knowledge, and the common perception is that patients are happy to receive the nurses’ advice regarding basic hygiene. It appears that the nurses find that there are no social structures that can help people maintain good health, despite their own efforts to maintain good health, there is not always prerequisite to maintain it. The community health workers are considered important for all people entitled to experienced health, for human rights and for people to get the right care when they need it. / Titel: Egenvård vid gastroenterit i Tanzania - Sjuksköterskors perspektiv. Enligt Världshälsoorganisationen dör 1,5 miljoner människor varje år på grund av diarrésjukdomar. Diarrésjukdomar kan bero på flera olika orsaker, däremot framhäver Världshälsoorganisationen att 58% av dessa orsakas av brist på rent vatten, sanitär utrustning och hygien. En kvalitativ studie utförd med sjuksköterskor som arbetar vid olika avdelningar på ett sjukhus i Tanzania. Semistrukturerade intervjuer genomfördes med 10 sjuksköterskor och intervjuerna analyserades med en kvalitativ innehållsanalys. Syftet var att beskriva sjuksköterskors upplevelse av arbetet med egenvård för patienter som är drabbade av gastroenterit. Sjuksköterskor beskriver att de upplever att patienter behöver mer kunskaper gällande egenvård, och den gemensamma uppfattningen är att patienterna är tacksamma för att få sjuksköterskans råd angående basal hygien. Det framkommer att sjuksköterskorna upplever att det saknas samhälleliga strukturer som kan hjälpa människor att kunna bibehålla en god hälsa, trots deras egna försök att upprätthålla en god hälsa så finns inte alltid förutsättningen att underhålla den. De lokala hälsoarbetarna som finns anses vara viktiga för alla människors rätt till upplevd hälsa, för mänskliga rättigheter och för att människor ska få rätt vård när de behöver det.
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Detecção de rotavírus em amostras fecais de bovinos e água em propriedades rurais do vale do Paranhana, RSBergamaschi, Bianca January 2012 (has links)
Objetivando aferir uma possível relação entre a contaminação de fontes aquáticas com o manejo de animais, o presente estudo buscou detectar a presença de rotavírus em amostras de fezes bovinas e águas coletadas nos municípios de Rolante, Riozinho e Taquara, no Rio Grande do Sul. Nestas localidades, pertencentes ao Vale do Paranhana, foram coletadas 104 amostras de água de diferentes origens, incluindo água de torneira, açude, poço cavado, poço artesiano, arroio, rio e vertente. As coletas de água foram realizadas nas proximidades das propriedades rurais e nas mesmas. Além disso, foram coletadas 38 amostras de fezes bovinas em propriedades de gado de leite. As amostras de água foram submetidas a um processo de concentração de partículas virais e o RNA foi extraído seguindo metodologia padronizada. Para detecção de RNA genômico, foi empregada a reação de transcriptase reversa seguida de reação em cadeia da polimerase (RT-PCR) tendo como alvo o gene mais conservado dos rotavírus, codificante da proteína VP6. Para avaliar a presença de vírus infeccioso, as amostras foram inoculadas em células MA-104, HEp-2 e CRIB. Das amostras de água, 25 (24%) continham genoma de rotavírus, sendo 8,6% amostras do município de Rolante, 4,8% de Riozinho e 10,6% amostras coletadas em Taquara. Estas 25 amostras contendo genoma viral foram subsequentemente submetidas ao isolamento em cultivos celulares, em nenhuma delas foi observado efeito citopático característico de rotavírus (CPE). A extração de RNA desses cultivos, após três passagens consecutivas, não revelou a presença de genoma viral. Em relação às amostras de fezes examinadas, em nenhuma delas foi detectada a presença de genoma de rotavírus. Conclui-se que o isolamento, como empregado no presente estudo, não teve sensibilidade suficiente para viabilizar seu uso como técnica para identificar rotavírus como contaminante de águas. Vinte e quatro por cento das amostras de água continham rotavírus, mas sua origem ainda deve ser determinada. / The aim of present study was to assess a possible relationship between the contamination of water sources with animal husbandry in the region. In the localities belonging to Paranhana valley, the municipalities of Taquara, Rolante e Riozinho, were collected 104 water samples from different sources including tap water, ponds, dug wells, boreholes, streams, river and slopes. The water samplings were conducted in the vicinity of farms and on them. In addition, 38 fecal samples were collected from cattle dung from animals on propertie of dairy in Taquara.Water samples were subjected to a process of viral particles concentration and RNA extraction following standard methodology. For genomic RNA detection, were used reverse transcriptase followed by polymerase chain reaction (RT-PCR) targeting the most conserved gene of rotaviruses, gene encoded the viral protein 6 (VP6).To evaluate the presence of infective viruses samples were inoculated on MA-104 cells, HEp-2 and CRIB. Of all water samples, 25 (24%) contained genome of rotavirus, 8,66% samples from Rolante, 4,81% samples from Riozinho and 10, 59 samples collected on Taquara. The 25 samples containing viral genome which all were subsequently subjected to isolation in cultured cells, none were observed cytopathic effect typical of rotavirus (CPE). RNA extraction of these inoculations after three consecutive passages did not reveal the presence of rotavirus genomes. Regarding the stool samples, none were detected presence of rotavirus genome. Viral isolation, as used in this study did not have sufficient sensitivity to enable its use as a technique for rotavirus identification as water contamination.
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Determinación de la ausencia de la infección de Aujeszky, gastroenteritis transmisible y coronavirus respiratorio en la principal zona de producción porcina de ColombiaRojas Morea, Diego Ricardo January 2018 (has links)
Tesis para optar al Grado de Magíster en Ciencias Animales y Veterinarias / El sector porcícola en Colombia ha venido creciendo de manera sostenida por encima del 6% anual desde 2010, sumado al incremento del consumo per cápita que ha pasado de 3.3 Kg/ hab/año en el año 2004 a 8.6 Kg/hab /año en el año 2016.
Este crecimiento, está acompañado de mejores indicadores de productividad y mejores condiciones de bioseguridad. Debido a esto la Asociación Colombiana de Porcicultores con el acompañamiento y aval de la Autoridad Sanitaria – ICA ha estructurado un trabajo conjunto para el mejoramiento del estatus sanitario nacional fundamentado en la evaluación de ciertas enfermedades que generan problemas clínicos, tienen un impacto económico en la producción porcina nacional y limitan el proceso exportador de productos derivados de los porcinos.
En la actualidad Colombia cuenta con la principal región de producción porcícola reconocida por la Organización Mundial de Sanidad Animal – OIE como libre de Peste Porcina Clásica, la cual comprende los departamentos de Antioquia, Caldas, Quindío, Risaralda, Valle del Cauca y Norte del Cauca. Esta zona concentra el 70% de la porcicultura tecnificada del país y cuenta con una serie de barreras geográficas y medidas sanitarias que le posicionan como una zona estratégica para el desarrollo de la porcicultura nacional y la consolida como una región con potencial para la exportación de carne de cerdo y sus productos.
El objetivo del presente trabajo es demostrar la ausencia de la enfermedad de Aujeszky, Gastroenteritis Transmisible y Coronavirus Respiratorio, en la principal zona de producción porcícola tecnificada conformada por los departamentos de Antioquia, Caldas, Quindío, Risaralda, Valle del Cauca y Norte del Cauca a través de un estudio sero epidemiológico.
En total se tomaron 2930 muestras en 486 predios para la enfermedad de Aujeszky y 1038 muestras en 165 predios para TGEV y Coronavirus respiratorio, con un 1% de prevalencia predial, una sensibilidad de la prueba diagnóstica del 100% y un 95% de nivel de confianza. Las técnicas diagnósticas empleadas fueron ELISA y como prueba confirmatoria se empleó la técnica de seroneutralización para Aujeszky y RT – PCR para TGEV – coronavirus.
Los resultados del estudio permiten inferir la ausencia de infección por virus de la enfermedad de Aujeszky, Gastroenteritis Transmisible y Coronavirus Respiratorio porcino en los departamentos que conforman la principal región de producción porcícola de Colombia con un nivel de confianza del 95% / The pork sector in Colombia has been growing steadily above 6% per year since 2010, added to the increase in per capita consumption that has gone from 3.3 Kg / inhabitant / year in 2004 to 8.6 Kg / inhabitant / year in the year 2016.
This growth is accompanied by better productivity indicators and better biosecurity conditions. Due to this, the Colombian Association of Producers with the support and endorsement of the Health Authority - ICA has structured a joint work for the improvement of the national sanitary status based on the evaluation of certain diseases that generate clinical problems, have an economic impact on the production swine and limit the export process of porcine products.
Currently, Colombia has the main pig production region recognized by the World Organization for Animal Health - OIE as free of Classical Swine Fever, which includes the departments of Antioquia, Caldas, Quindío, Risaralda, Valle del Cauca and Norte del Cauca. This area concentrates 70% of the country's technically-procured swine and has a series of geographical barriers and sanitary measures that position it as a strategic area for the development of national pork production and consolidates it as a region with potential for meat exports of pork and its products.
he objective of the present work is to demonstrate the absence of Aujeszky's disease, Transmissible Gastroenteritis and Respiratory Coronavirus, in the main area of high-tech porcine production formed by the departments of Antioquia, Caldas, Quindío, Risaralda, Valle del Cauca and Norte del Cauca through a sero epidemiological study.
A total of 2930 samples were taken in 486 farms for Aujeszky's disease and 1038 samples in 165 farms for TGEV and respiratory Coronavirus, with a 1% prevalence of predials, a sensitivity of the diagnostic test of 100% and a 95% level of trust. The diagnostic techniques used were ELISA and as a confirmatory test the sero neutralization technique was used for Aujeszky and RT - PCR for TGEV - coronavirus.
The final results allow to infer the absence of infection by Aujeszky's disease virus, Transmissible Gastroenteritis and Porcine Respiratory Coronavirus in the departments that make up the main pig production region of Colombia with a confidence level of 95%.
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Detecção de rotavírus em amostras fecais de bovinos e água em propriedades rurais do vale do Paranhana, RSBergamaschi, Bianca January 2012 (has links)
Objetivando aferir uma possível relação entre a contaminação de fontes aquáticas com o manejo de animais, o presente estudo buscou detectar a presença de rotavírus em amostras de fezes bovinas e águas coletadas nos municípios de Rolante, Riozinho e Taquara, no Rio Grande do Sul. Nestas localidades, pertencentes ao Vale do Paranhana, foram coletadas 104 amostras de água de diferentes origens, incluindo água de torneira, açude, poço cavado, poço artesiano, arroio, rio e vertente. As coletas de água foram realizadas nas proximidades das propriedades rurais e nas mesmas. Além disso, foram coletadas 38 amostras de fezes bovinas em propriedades de gado de leite. As amostras de água foram submetidas a um processo de concentração de partículas virais e o RNA foi extraído seguindo metodologia padronizada. Para detecção de RNA genômico, foi empregada a reação de transcriptase reversa seguida de reação em cadeia da polimerase (RT-PCR) tendo como alvo o gene mais conservado dos rotavírus, codificante da proteína VP6. Para avaliar a presença de vírus infeccioso, as amostras foram inoculadas em células MA-104, HEp-2 e CRIB. Das amostras de água, 25 (24%) continham genoma de rotavírus, sendo 8,6% amostras do município de Rolante, 4,8% de Riozinho e 10,6% amostras coletadas em Taquara. Estas 25 amostras contendo genoma viral foram subsequentemente submetidas ao isolamento em cultivos celulares, em nenhuma delas foi observado efeito citopático característico de rotavírus (CPE). A extração de RNA desses cultivos, após três passagens consecutivas, não revelou a presença de genoma viral. Em relação às amostras de fezes examinadas, em nenhuma delas foi detectada a presença de genoma de rotavírus. Conclui-se que o isolamento, como empregado no presente estudo, não teve sensibilidade suficiente para viabilizar seu uso como técnica para identificar rotavírus como contaminante de águas. Vinte e quatro por cento das amostras de água continham rotavírus, mas sua origem ainda deve ser determinada. / The aim of present study was to assess a possible relationship between the contamination of water sources with animal husbandry in the region. In the localities belonging to Paranhana valley, the municipalities of Taquara, Rolante e Riozinho, were collected 104 water samples from different sources including tap water, ponds, dug wells, boreholes, streams, river and slopes. The water samplings were conducted in the vicinity of farms and on them. In addition, 38 fecal samples were collected from cattle dung from animals on propertie of dairy in Taquara.Water samples were subjected to a process of viral particles concentration and RNA extraction following standard methodology. For genomic RNA detection, were used reverse transcriptase followed by polymerase chain reaction (RT-PCR) targeting the most conserved gene of rotaviruses, gene encoded the viral protein 6 (VP6).To evaluate the presence of infective viruses samples were inoculated on MA-104 cells, HEp-2 and CRIB. Of all water samples, 25 (24%) contained genome of rotavirus, 8,66% samples from Rolante, 4,81% samples from Riozinho and 10, 59 samples collected on Taquara. The 25 samples containing viral genome which all were subsequently subjected to isolation in cultured cells, none were observed cytopathic effect typical of rotavirus (CPE). RNA extraction of these inoculations after three consecutive passages did not reveal the presence of rotavirus genomes. Regarding the stool samples, none were detected presence of rotavirus genome. Viral isolation, as used in this study did not have sufficient sensitivity to enable its use as a technique for rotavirus identification as water contamination.
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AnÃlise das doenÃas de veiculaÃÃo hÃdrica prevalentes em crianÃas no municÃpio de Crato-CE / Analysis of water release prevalent diseases in children in the municipality of Crato-CEAna Raquel Bezerra Saraiva 26 April 2013 (has links)
FundaÃÃo Cearense de Apoio ao Desenvolvimento Cientifico e TecnolÃgico / As doenÃas de veiculaÃÃo hÃdrica sÃo consideradas surtos caracterÃsticos de regiÃes, em que o abastecimento de Ãgua potÃvel e a estrutura sanitÃria encontram-se desorganizados e atà mesmo inexistentes. Objetivou-se traÃar um diagnÃstico das doenÃas de veiculaÃÃo hÃdrica prevalentes em crianÃas (na faixa etÃria de 0 a 4 anos) na cidade de Crato/CE. Trata-se de uma pesquisa quantitativa, do tipo documental, desenvolvida no municÃpio de Crato - CE. Com relaÃÃo ao nÃmero de crianÃas atendidas pelas Equipes de SaÃde da FamÃlia viu-se que na zona rural, no ano de 2010, 2096 crianÃas e na zona urbana 4812, jà no ano de 2011 na zona rural, 2012 crianÃas e na zona urbana 4319. A coleta pÃblica passou a atender 78,7% das famÃlias, com reduÃÃo na dispersÃo do resÃduo sÃlido em cÃu aberto para 10%. Houve um aumento das canalizaÃÃes das residÃncias passando para 35,6% das famÃlias, bem como um aumento do acesso à Ãgua prÃpria para consumo humano passando em mÃdia para 83,4% das famÃlias. Percebe-se que a Zona Rural, nos distritos de Campo Alegre, Monte Alverne e Dom Quintino, encontra-se recebendo Ãgua de outras fontes que nÃo a Rede PÃblica o que compromete a qualidade da saÃde. No ano de 2010, ocorreram 55 casos de dengue, com um de FHD, 6 casos de Leishmaniose Tegumentar, um caso de Hepatite A. No ano de 2011 foi possÃvel evidenciar 21 casos de Dengue, um caso de FHD, 4 casos de Leishmaniose Tegumentar, e uma notificaÃÃo de Hepatite A. Quanto a Gastroenterite, no ano de 2010 e 2011, foram acometidas 1039 e 930 crianÃas respectivamente, jà no HMSFA nos respectivos anos, foram atendidas 1043 e 766 crianÃas. Percebe-se que as DVH sÃo encontradas em regiÃes em que nÃo hà planejamento urbano, acesso à Ãgua de qualidade, distribuiÃÃo desigual de renda, ausÃncia de saneamento bÃsico, bem como, estÃo relacionadas com o desenvolvimento In-SustentÃvel. Dessa maneira, todas as suas formas de transmissÃo e contÃgio poderiam ser quebradas melhorando a renda, a moradia, o saneamento, serviÃos essenciais que possibilitam a qualidade de vida da populaÃÃo. Cabe, assim, aos gestores, observar a cadeia das DVH e trabalhar para que as comunidades recebam a assistÃncia com acesso igual e de qualidade, favorecendo a saÃde. / The water-borne diseases are considered outbreaks from regions in which the drinking water supply and sanitary conditions are unorganized or even inexistent. The main aim of this work was to raise up a diagnosis about the water-borne diseases from Crato, CE. The documental quantitative research observed that in 2010 there were 2096 children attended by the Family health team in the countryside of the city, while there were 4812 in the urban area. In 2011, 2012 and 4319 children were attended in the countryside and urban area, respectively. The garbage gathering attended 78.9% with a reduction of the waste open to 10%. There was an increasing in the houses with sewage up to 36.5% with the families being attended, as well as there was an increasing of the access to own water to human consumption getting 83.4% of the families in average. It was observed the districts of Campo Alegre, Monte Alverne and Dom Quintino, in the countryside, get water from other sources than the public one. This implicates the health quality. Thus, it was observed that in 2010 it occuried 55 cases of dengue, being one of FHD; 6 cases of Cutaneous Leishmaniasis and one of Hepatitis A. In 2011, occurred 21 cases of dengue, being one of FHD; 4 cases of Cutaneous Leishmaniasis and one of Hepatitis A. It was registered 1039 and 930 cases of children with gastroenteritis in 2010 and 2011, respectively. In the same period, 1043 and 766 children were attended in the HMSFA. We can observe that the water-borne diseases are really related to regions that have not urban planning, access to good quality water, income distribution, sanitation, as well as they are related with the non- sustainable development. Thus, all the transmission and contamination ways could be pull out getting improvements in the conditions cite above. Therefore, it is up to managers observe the water-borne diseases chain and to work to pull out this conditions to improve the health conditions.
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