The Abraham solvation parameter model is a good approach for analyzing and predicting biological activities and partitioning coefficients. The general solvation equation has been used to predict the solute property (SP) behavior of drug compounds between biological barriers. Gas chromatography (GC) retention time can be used to predict molecular descriptors, such as E, S, A, B & L for existing and newly developed drug compounds. In this research, six columns of different stationary phases were used to predict the Abraham molecular descriptors more accurately. The six stationary phases used were 5% phenylmethyl polysiloxane, 6% cyanopropylphenyl 94% dimethylpolysiloxane, 5% diphenyl 95% dimethylpolysiloxane, 100% dimethylpolysiloxane, polyethylene glycol and 35% diphenyl 65% dimethylpolysiloxane. Retention times (RT) of 75 compounds have been measured and logarithm of experimental average retention time Ln(RTexp) are calculated. The Abraham solvation model is then applied to predict the process coefficients of these compounds using the literature values of the molecular descriptors (Acree Compilation descriptors). Six correlation equations are built up as a training set for each of the six columns. The six equations are then used to predict the molecular descriptors of the illegal drugs as a test set. This work shows the ability to extract molecular information from a new compound by utilizing commonly used GC columns available with the desired stationary phases. One can simply run the new compound in GC using these columns to get the retention time. Plugging in the retention time into the developed equations for each of the column will predict the molecular descriptors for the test compound and will give some information about the properties of the compound.

Illegal drug use is perceived as immoral, criminogenic, and an unhealthy practice for decades under the discourse sustaining drug prohibition. Those who apply prohibition laws on the front lines are narcotic police officers, particularly the ones who work in narcotic squads. Based on the specific context in which these individuals work in, perceptions and meanings on drug prohibition and illegal drug use will emerge. This project will explore drug enforcement officer’s perceptions on Canadian drug legislation and illegal drug use through the mobilization of Maurice Merleau-Ponty’s interpretation of phenomenology and social problems theory.

Wastewater-based epidemiology can be used to analyse substances in wastewater and serve as a tool to examine the illegal drug consumption in a population. The aim of this study was to analyse concentrations of illegal drugs in wastewater from Öns wastewater treatment plant in Umeå, Sweden and i) compare concentrations of illegal drugs with previous studies from 11 and 9 years ago, ii) examine the weekly variation and iii) examine how Umeå's levels of drugs in wastewater relate to other cities in Sweden and Europe. The method used is flow proportional sampling. Three samples were collected on Monday (24-hours), Wednesday (24-hours) and a combined sample from the weekend (Friday, Saturday, Sunday, i.e., 72-hours), the samples were transferred to vials containing sodium thiosulfate (Na2S2O3), they were transported refrigerated to a laboratory in Prague, Czech Republic, where the analysis was performed. This study gives strong indications that cocaine use has increased in Umeå over the past decade and is thus in line with the increasing trend of cocaine being measured in wastewater in other European cities. This study also provides indications that the use of amphetamine has increased in Umeå over the last decade and supports previously observed trends of high amphetamine levels in Sweden in comparison with the rest of Europe. The analysis indicates higher cocaine use on weekends compared to weekdays, while amphetamine use was more evenly distributed over the week.

Victims of teen dating violence (TDV) in the United States engage in risk behaviors that increase their vulnerability to ill health. Although teen dating violence affects millions of adolescents of diverse ethnic backgrounds, there is a higher prevalence of TDV among Blacks and Latinos. In order to develop effective interventions for diverse populations, it is critical to understand the risk behaviors associated with different victims of TDV. The purpose of this thesis is to determine whether there is a difference between the risk behaviors (alcohol abuse, illegal drug use and perilous sexual intercourse) engaged in by Black, Latino and White adolescent victims of TDV. The national 2005 Youth Risk Behavior Survey (YRBS) was the source of data. This thesis hypothesizes that there are different risk behaviors related to each ethnic group, and aims to provide information to support the development of culturally competent TDV interventions.

The thesis research the frequency of illegal drugs use by student sof Univerzity of South Bohemia in the Czech Budějovice. In the theoretical part are characterized by drugs, illegal drugs and the effects of drug use on health, describes the emergence of drug addiction and its types and developmental stages of drug use. Furthermore, illegal drugs are divided into categories according to their effects and further described. The main aim of the practical part is the analysis of illegal drug use by students of the University of South Bohemia. On the basis of a questionnaire compiled data was found and it was statistically analyzed by the method, compares and conclusions were drawn. Over the past year have used an illegal drug 37.83% of respondents, that 2.91% of the respondents use illegal drugs daily. Earlier experience with illegal drugs has 18.78% of students of the University of South Bohemia. Past experience with drugs is more common in women, while use in the last year is much more common in men. The most commonly used substances are cannabinoids, as well as hallucinogens, opiates and finally stimulanci.

Drug taking brings a many complications for whole society - not only in health district but also in social and economics. The purpose of this work was charting and regarting theoretic knowledges in dope problematic of pupils in primary schools and primary practical schools and find out which group is more in danger. In solving of drug problematic I am taking accound most important very qualitative drug prevention as in families as in effective preventative programmes, good work of pedagogues and in enough of out of school activities for impletion of free time puppy fat.

Introduction: The Police in Sundsvall has identified a problem of an open drug market in the inner city of Sundsvall. Behind an open drug market there is an organization that consists of several steps. Internet also contributes to a drug trafficking. There is research about how the illegal drugs arrive to Sweden, but no research about what happens with the drugs after they have entered Sweden. Aim: The study aimed to examine how the national drug trafficking provides an illegal local drug market in Sundsvall with illegal drugs in a medium sized city in the middle of Sweden. In order to do so, the researchers studied the most common illegal drugs that are transported to the local market and how the illegal drugs arrive to the local market. Method: This study has a mixed method design and are divided into three parts. The first part is quantitative and consists of statistics from the Board of Customs. The second part is qualitative and consists of interviews with professionals from the Police and Customs and also with former drugs dealers and one heavy user. The third part is also qualitative and consists of interviews from Postnord, DHL, the Customs and the Police. Results: It was concluded in the results that cannabis and amphetamine were the most common illegal drugs on the local market in Sundsvall. It was also found that there are no specific routes that the illegal drugs are transported along to Sundsvall. It rather depends on the contacts that each local seller in Sundsvall has. Internet and the logistic companies were found to play an important role regarding the means for transportation. Discussion: The consequences and underlying causes of the phenomena was discussed. Also, two criminological theories were applied in order to explain what motivates people to involve in the transportation of illegal drugs to the local market and thus why illegal drugs are transported. / <p>2017-06-01</p>

The problem with which this investigation is concerned is discovering if there are any differences in knowledge and sources of knowledge about illegal drugs between rural and metropolitan high school seniors. The term "drugs" in this project includes those defined by law as illegal and also those drugs subject to abuse through misuse. The report concludes that both correct drug knowledge and attitudes toward drugs seem to depend upon the degree to which drugs have entered into the community and their availability. Since no actual differences in knowledge were discovered, the indication is that possibly rural and metropolitan areas can no longer be separated as to the reasons for, or the extent of, certain social problems.

People who use illegal drugs all too often experience stigma and discrimination, criminalization and marginalization in Canada. Substance use has both immediate and chronic health consequences that may require healthcare. However, people who use illegal drugs often experience difficulty accessing equitable care, and stigma has been identified as a key barrier to access. This study explores the provision of health care by nurses in an emergency department for people who use illegal drugs, and the impact of hospital policies and procedures on nurses’ capacity to provide care. The study uses data from in-depth interviews with nurses and policy leaders, and analyses policy documents discussed by nurses in the interviews. This study found that neoliberal policies that result in downsizing of social programs means that patients come to emergency departments with a broad set of health and socials needs that extend beyond what nurses can do. The study also uncovered a lack of cultural safety for Aboriginal patients seeking care. Finally, the study discovered the existence of a culture of stigma in the emergency department. The culture of stigma is transmitted and taken up through individual attitudes, relations of power, intake and treatment protocols, critical policy absences and problematic policy. This study concludes with recommendations for policy development and for future research in this area. / Graduate / 0680 / 0573 / 0569 / heyriver@shaw.ca

People who use illegal drugs all too often experience stigma and discrimination, criminalization and marginalization in Canada. Substance use has both immediate and chronic health consequences that may require healthcare. However, people who use illegal drugs often experience difficulty accessing equitable care, and stigma has been identified as a key barrier to access. This study explores the provision of health care by nurses in an emergency department for people who use illegal drugs, and the impact of hospital policies and procedures on nurses’ capacity to provide care. The study uses data from in-depth interviews with nurses and policy leaders, and analyses policy documents discussed by nurses in the interviews. This study found that neoliberal policies that result in downsizing of social programs means that patients come to emergency departments with a broad set of health and socials needs that extend beyond what nurses can do. The study also uncovered a lack of cultural safety for Aboriginal patients seeking care. Finally, the study discovered the existence of a culture of stigma in the emergency department. The culture of stigma is transmitted and taken up through individual attitudes, relations of power, intake and treatment protocols, critical policy absences and problematic policy. This study concludes with recommendations for policy development and for future research in this area. / Graduate / 0680 / 0573 / 0569 / heyriver@shaw.ca